<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="https://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRC1</accession>
    <name>C1KRC1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Translation initiation factor IF-1, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">infA</name>
        <name evidence="10" type="ORF">MicpuC_chl20</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="10"/>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the IF-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRC1"/>
    <dbReference type="STRING" id="564608.C1KRC1"/>
    <dbReference type="OMA" id="EGHQCLC"/>
    <dbReference type="OrthoDB" id="1714886at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000002">
        <property type="entry name" value="Translation initiation factor IF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 7 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00068272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACO50753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="85" mass="9577" checksum="AFF5EBF33B026A8D" modified="2009-05-26" version="1">MSDRELIEMEGTVIESLPNAMFQVELENGFQVLAHISGKIRRNSIKILLGDRVIVELTPYDLTKGRITYRLRNTDKGNPGTSKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGN7</accession>
    <name>C1MGN7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_49881</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054809.1">
        <property type="nucleotide sequence ID" value="XM_003054763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGN7"/>
    <dbReference type="STRING" id="564608.C1MGN7"/>
    <dbReference type="GeneID" id="9680609"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49881"/>
    <dbReference type="eggNOG" id="KOG0804">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WADASCP"/>
    <dbReference type="OrthoDB" id="273556at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16457">
        <property type="entry name" value="RING-H2_BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011422">
        <property type="entry name" value="BRAP2/ETP1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047243">
        <property type="entry name" value="RING-H2_BRAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007:SF7">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07576">
        <property type="entry name" value="BRAP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="228"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="7">
        <location>
            <begin position="265"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="18"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="349"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="602"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="369"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="605"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="648" mass="68869" checksum="16CD0794194CFF3E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH02</accession>
    <name>C1MH02_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_13078</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055409.1">
        <property type="nucleotide sequence ID" value="XM_003055363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH02"/>
    <dbReference type="STRING" id="564608.C1MH02"/>
    <dbReference type="GeneID" id="9680560"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13078"/>
    <dbReference type="eggNOG" id="KOG2343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="269405at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057983">
        <property type="entry name" value="NAA35-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007244">
        <property type="entry name" value="Naa35_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373">
        <property type="entry name" value="GLUCOSE REPRESSIBLE PROTEIN MAK10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373:SF0">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04112">
        <property type="entry name" value="Mak10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAA35-like N-terminal" evidence="1">
        <location>
            <begin position="27"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="159" mass="17176" checksum="9E5BB45834E48B99" modified="2009-05-26" version="1" fragment="single">RPPRAMGPSWVPVDDVLAAATTRMTSGELVHGATFDLFASMSAITVGDRKMDVGVEGGMDGLAPPFQTSEKLVAAGRAPLELTDEEQIYVFDALLACEATWHSGQSLAVSIYTCLYMHDFDRLEASSSPVTRAYFDAVRSDVATVRNAVSLGDVWEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH71</accession>
    <name>C1MH71_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_50072</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054902.1">
        <property type="nucleotide sequence ID" value="XM_003054856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH71"/>
    <dbReference type="STRING" id="564608.C1MH71"/>
    <dbReference type="GeneID" id="9680794"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50072"/>
    <dbReference type="eggNOG" id="KOG1700">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6129702at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09443">
        <property type="entry name" value="LIM_Ltd-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09358">
        <property type="entry name" value="LIM_Mical_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000002">
        <property type="entry name" value="LIM domain and actin-binding 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24206">
        <property type="entry name" value="OS06G0237300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="28"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="140"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="304"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="490"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="415"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="553" mass="57990" checksum="52C1D5361013B122" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHK1</accession>
    <name>C1MHK1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50226</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055507.1">
        <property type="nucleotide sequence ID" value="XM_003055461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHK1"/>
    <dbReference type="GeneID" id="9680568"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50226"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="482" mass="53783" checksum="280A077ADA316A48" modified="2009-05-26" version="1">MVHVSLEDDWHILKVRDRARHDTASESPASFRRSTACCVIPDLLTTIILLSRDNTLQADLDTTLSHAQVYYALRKLLRSASPVFHITCDGQVLTDANACWLVKTGSVVKIQPGEAPAHLKAQRGVTVIDKNAPPPGVTSAGAAPPVTITSSTPRRVTPDTGARRLEGGWKPKAKEGADFGATRKSGNGRRNLDRRDAPATTVRVPVAGVHSSLRQELASEDLSAWMRSYKSEEDAFSSSALLAETRYNEVVKSTESLGTPNLVRTREVCRLLEAIVMRFGRFRGITRKLLDDVFHSVFEDPNAPNAEPYFLKHSRVQNQLREQRCKNALLDKEVAGVQANSAKRFAFIQRTLANVFNQSMVSAFRKWRTEVQQISAKKEVLRNMTAKARRTISRKALGHWRVCAVLCRLEKAYVVVKEKTDASEQLREKASERERERDAASHEVDVMKNQMQLLQKKLAETEARAVAAETELAKHKAVDDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHN6</accession>
    <name>C1MHN6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">U6 snRNA-associated Sm-like protein LSm5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LSM5</name>
        <name evidence="12" type="ORF">MICPUCDRAFT_13524</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054987.1">
        <property type="nucleotide sequence ID" value="XM_003054941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHN6"/>
    <dbReference type="STRING" id="564608.C1MHN6"/>
    <dbReference type="GeneID" id="9680578"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13524"/>
    <dbReference type="eggNOG" id="KOG1775">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YETTPQG"/>
    <dbReference type="OrthoDB" id="429711at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01732">
        <property type="entry name" value="LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000003">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033871">
        <property type="entry name" value="LSm5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971:SF0">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="9"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH60239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="88" mass="9837" checksum="A85709A253B78AE9" modified="2009-05-26" version="1">MATNPSQLLPSELVDRCVGSRIWVIMKGEKEMVGTLRGFDVYVNMVLEDVIEYEMTPEGKRVTKLDQILLNGNNIALLVPGGMPDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHW5</accession>
    <name>C1MHW5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_46272</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055026.1">
        <property type="nucleotide sequence ID" value="XM_003054980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHW5"/>
    <dbReference type="STRING" id="564608.C1MHW5"/>
    <dbReference type="GeneID" id="9681130"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46272"/>
    <dbReference type="eggNOG" id="ENOG502QWFV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="566980at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057228">
        <property type="entry name" value="DUF7906"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31515:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31515">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25483">
        <property type="entry name" value="DUF7906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002911945" evidence="2">
        <location>
            <begin position="37"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7906" evidence="3">
        <location>
            <begin position="107"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="797"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="797"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="979" mass="103270" checksum="DE9F72CE22E8E928" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHY4</accession>
    <name>C1MHY4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_50366</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055037.1">
        <property type="nucleotide sequence ID" value="XM_003054991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHY4"/>
    <dbReference type="GeneID" id="9681138"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50366"/>
    <dbReference type="OrthoDB" id="10678271at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="316" mass="35882" checksum="1496387A32C40A8D" modified="2009-05-26" version="1">MASSDDMARLDVSTDLACVILSKIHDVPTRAALMCVSRVWREAGKEKTSFPKELDFTTVPNLANATYEKIAAFMDRIEGIHIRLPPGSEWPRKKLHDGVALDRMRLKGTTVASWELTPLDFYVKHDRRKVRAFDNGPFDVWCCGNNCDTILDNERKHSVCIACDGKDTHVLCVGCADADTYHMFCEKCNAFDCNENYMEECANCEGWICMECSFICNQCDKTFCYDCNFGMCCSGSYKWKNGKACYRTYCEDCAFGEIFFCEACQGDWCEKCNDSFVCFGSDEQKGCSVTRCVDCQSHGWTRELDELAKARRRAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI11</accession>
    <name>C1MI11_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_37998</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxin-11 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055585.1">
        <property type="nucleotide sequence ID" value="XM_003055539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI11"/>
    <dbReference type="STRING" id="564608.C1MI11"/>
    <dbReference type="GeneID" id="9681042"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37998"/>
    <dbReference type="eggNOG" id="KOG4186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VSTHKNW"/>
    <dbReference type="OrthoDB" id="411017at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044375">
        <property type="term" value="P:regulation of peroxisome size"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF50">
        <property type="entry name" value="PEROXIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="346" mass="37485" checksum="89118F1922D99FF8" modified="2009-05-26" version="1">MSDVVSEASSAPSLSDVDDDDDDRHRVVAGPASSARSSRGPPPLKPASSSRLTSPPPESKPSPDVLDHAVDFLKTRDGMDKMLKLMRYAAALTALATTNAKLSKLERYTALTRKFLRLGRFLGNAKELRDLSRTSRRLSRLGATATAGGDDIARQRHRASVTVNNLAIACQGVQLAYNLLEQGNWATRTRLVTNERWKRTFSVGANYAELAVCFFSAQLHALALRDLDRRAREIADAMEARRRVAAAAAAKGAFAPRRRPWKKSDGVSYDELDDEVLDALLANVARERWTRRVNLAQDALDAAAVAGDVVGGGNAFQRPVVVGALGLLSAMFGAYDKWVATAPASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI50</accession>
    <name>C1MI50_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50438</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055068.1">
        <property type="nucleotide sequence ID" value="XM_003055022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI50"/>
    <dbReference type="STRING" id="564608.C1MI50"/>
    <dbReference type="GeneID" id="9681173"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50438"/>
    <dbReference type="eggNOG" id="ENOG502SBK5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="224" mass="24761" checksum="143EF5F5C861D714" modified="2009-05-26" version="1">MRTHSSSGFNTIPENVAAVVLSHLTDPEDRVRLAAVSKVWRDAEKGGVVSLPGTSSELSELGQEFRSAHKHGKAIYWFEKSADHGDPEGMFWFASYTFAGYTGGACTEENYNKAVHWWKRASELGHAEATKMVATCYEDGHGVERDFAKAIEWHVKAAELGCGFSASWLGSAHLYGRHGLTPNTKEALKWFRLALELGDANAREPWWEVSRINAHVLEAELAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI54</accession>
    <name>C1MI54_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50442</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055607.1">
        <property type="nucleotide sequence ID" value="XM_003055561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI54"/>
    <dbReference type="GeneID" id="9680934"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50442"/>
    <dbReference type="OMA" id="CNCEAYA"/>
    <dbReference type="OrthoDB" id="514794at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011692">
        <property type="entry name" value="Stress_up-reg_Nod19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33390">
        <property type="entry name" value="STRESS UP-REGULATED NOD 19 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33390:SF1">
        <property type="entry name" value="STRESS UP-REGULATED NOD 19 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07712">
        <property type="entry name" value="SURNod19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910253" evidence="2">
        <location>
            <begin position="18"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="3">
        <location>
            <begin position="611"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="766" mass="80959" checksum="8F1DACEAC9C1A37D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIU8</accession>
    <name>C1MIU8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_38171</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">PML body</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055726.1">
        <property type="nucleotide sequence ID" value="XM_003055680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIU8"/>
    <dbReference type="STRING" id="564608.C1MIU8"/>
    <dbReference type="GeneID" id="9681036"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38171"/>
    <dbReference type="eggNOG" id="KOG2756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VESFNCK"/>
    <dbReference type="OrthoDB" id="9975959at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070260">
        <property type="term" value="F:5'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09080">
        <property type="entry name" value="TDP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051547">
        <property type="entry name" value="TDP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15822">
        <property type="entry name" value="TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15822:SF4">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="12">
        <location>
            <begin position="287"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="198"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH60978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="566" mass="60363" checksum="E7C18D31D07A8078" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIV2</accession>
    <name>C1MIV2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase HISN3, chloroplastic</fullName>
            <ecNumber evidence="7">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-proFAR isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_50705</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="7"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055727.1">
        <property type="nucleotide sequence ID" value="XM_003055681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIV2"/>
    <dbReference type="STRING" id="564608.C1MIV2"/>
    <dbReference type="GeneID" id="9680361"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50705"/>
    <dbReference type="eggNOG" id="KOG3055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SSHFCVR"/>
    <dbReference type="OrthoDB" id="446074at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04723">
        <property type="entry name" value="HisA_HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011858">
        <property type="entry name" value="His6/HISN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02129">
        <property type="entry name" value="hisA_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090:SF2">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="20"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="322" mass="34730" checksum="B8C841A8DAD0C1A1" modified="2009-05-26" version="1">MSAAVHLGGVRAPVRVARASRVDRRPTRAGRATSASAAISSSEKNVPRAGRFPPGIDIHQGRVKQIVGGTLKDAPHGSPASETPETNFQTETSSAEFARMYRRDDVRGGHVIMLSRDDATLQAAMDAVSAFPNGLQVGGGVTAETAAPLLDAGASHVIVTSYVFRDGMVDQERLDALVAAVGKERVVLDLSCRKKGDEYYVVTDRWQKWTDLKVDEETMRELAKHCDEFLVHGVDVEGMKLGVDEELVRRLGVRSPIPVTYAGGARSLDDLELVRRPGGGRVDVTVGSALDCFGGELKYDDVVAWHDHQKTLAGIVCDDPEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ36</accession>
    <name>C1MJ36_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50794</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055766.1">
        <property type="nucleotide sequence ID" value="XM_003055720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ36"/>
    <dbReference type="GeneID" id="9680546"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50794"/>
    <dbReference type="eggNOG" id="KOG1919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GEHHSYK"/>
    <dbReference type="OrthoDB" id="424794at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF52">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="2">
        <location>
            <begin position="168"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH61018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="483" mass="51233" checksum="191F9A2135D5B554" modified="2009-05-26" version="1">MASMLRRVVTASTGGGGGASASAGAGASANARTTRALRLTDAPPPTPLPPRVKHVVLGPDAFGPAATIVASALGLPDVDARYARQLIEFGAVYYSDVPPPRPRAASGSGSSSSTNNKRDPSATPQRVKSANRVVHPGGYLRVHVHPKRFPAARATDWRRAIIAAGDAFVVVDKPAGVNVGFTVDNAKECVAQCVARALGDAFAENGSDSSSTDSSTECSSWGWADATPLIVTHRLDAATSGVLVLARDVEFARHFNDALRERKVQKTYACVSEARVPVGVMEHWTDPEDATRGPRRHVMRPPREGDTPWEERGGGGGETSTSIAEERAEKAAATTSKQKKSQRQKKRERRLAKAEEFVHPDGRRRCVLRVLTCEEVKIPGEKAGDAPPRYESTVELVTGRTHQIRAQFAASGAPLLGDVLYGGARVGRGTGEGEGEGEAPRVLGNDDALCLHASEIRVDVAGPLGRSGTTFKASPPWWRRGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJJ7</accession>
    <name>C1MJJ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54984</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055832.1">
        <property type="nucleotide sequence ID" value="XM_003055786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJJ7"/>
    <dbReference type="GeneID" id="9681866"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54984"/>
    <dbReference type="OrthoDB" id="7250310at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="210" mass="22866" checksum="626FDB0D1427782F" modified="2009-05-26" version="1">MATAAWTASPTRALAPSRRASSSSSSSSSAASSSSSSSSSSSRSSFRRWRGGCRTRLASRMARATSKRDDDDAADAVATSENVGDKAKSALTELVVRPFTSFIVERVLSPLYETRDAKRDECGPGMYTDPRTETCVFICRERRLYAHDGEGIVDRFVRFFVNKLTGAGGDCDVGFFYDPATRACVPICKPGYVYDPTVKKCVAMEDELRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJM2</accession>
    <name>C1MJM2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_71043</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056237.1">
        <property type="nucleotide sequence ID" value="XM_003056191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJM2"/>
    <dbReference type="STRING" id="564608.C1MJM2"/>
    <dbReference type="GeneID" id="9681874"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_71043"/>
    <dbReference type="eggNOG" id="ENOG502RZEV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TSKSASW"/>
    <dbReference type="OrthoDB" id="495741at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021995">
        <property type="entry name" value="DUF3593"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019634">
        <property type="entry name" value="Uncharacterised_Ycf49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33833">
        <property type="entry name" value="NUCLEOLAR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33833:SF3">
        <property type="entry name" value="YCF49-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10693">
        <property type="entry name" value="DUF2499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12159">
        <property type="entry name" value="DUF3593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="623" mass="64431" checksum="E591BFB654E987DC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJQ5</accession>
    <name>C1MJQ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PDZ domain protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55055</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055861.1">
        <property type="nucleotide sequence ID" value="XM_003055815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJQ5"/>
    <dbReference type="GeneID" id="9681280"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55055"/>
    <dbReference type="OrthoDB" id="10033291at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="67"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="179" mass="17947" checksum="F05467A3C49FF654" modified="2009-05-26" version="1">MGQVQRPSVLVRARPDLDDDLASARAASARAAAAAALASVVAAASIHLARATPPAIAAAASASEASGYVGVGLEVYVAPDGYPTVIEFLPTKTSGPAHDAGVRINDKIAAVNGAETRAMRCLADVASALRGGGAGGDAVELTLLRRRGRTTETVAASVTRVGGITPNPRSCFVSSCARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJU1</accession>
    <name>C1MJU1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55095</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055877.1">
        <property type="nucleotide sequence ID" value="XM_003055831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJU1"/>
    <dbReference type="STRING" id="564608.C1MJU1"/>
    <dbReference type="GeneID" id="9681644"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55095"/>
    <dbReference type="OrthoDB" id="2021042at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="275" mass="30029" checksum="4C50AF2DF5E6A45D" modified="2009-05-26" version="1">MASAAAAPRAPLVASGPRPSPRPRDGDRRRAPPRPRRGVLVVECRNRILFREDEVSRRPDGVAAARLARDDPRATHVRDVLKLALGDTLRVGVINDAPAVATVVAEGGGDDATLALEWRARRDDDDDDDDDDDARDASRRSIADGPTIELLLACPRPKALRRMWTSLAQLGVRVVTITPAWKARLVHLIQANNNAGPRARSRPPTPRFGFNSDAHAATPAFRLRLTPFNAFLSTPRAKTPKDYFGASSLLSRETVESGAFCERPHVFHPPLGFNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJV2</accession>
    <name>C1MJV2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_46496</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055885.1">
        <property type="nucleotide sequence ID" value="XM_003055839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJV2"/>
    <dbReference type="STRING" id="564608.C1MJV2"/>
    <dbReference type="GeneID" id="9681645"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46496"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000778">
        <property type="entry name" value="Cyt_b245_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00466">
        <property type="entry name" value="GP91PHOX"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="589"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="317"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="865" mass="98505" checksum="A5B17F7AF14F56E1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJY7</accession>
    <name>C1MJY7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_55151</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055901.1">
        <property type="nucleotide sequence ID" value="XM_003055855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJY7"/>
    <dbReference type="STRING" id="564608.C1MJY7"/>
    <dbReference type="GeneID" id="9681294"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55151"/>
    <dbReference type="OrthoDB" id="2015333at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF170">
        <property type="entry name" value="DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="4">
        <location>
            <begin position="270"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="310"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="379" mass="40435" checksum="915FEA59EF04CFE9" modified="2009-05-26" version="1">MNRTNAFSRGRRRPQAHGALGAALGAAALLNPALAYFREPPQPSAKPKPKRLAHALLGWIVVIGGGANVVLGRHAAADSKYDDVLDENVSLAQEAAGWTIAAVGVVGLLASISSRGGGGGRRRFTSSDGLNSNSNSETTTAWPSMTKEDVARCELYFDHVRDDGAGAGDGDVPRARESRVVEFLMKSGLPLATLRDVWTHIEAETDADGGVARIAFSKAFYLAEIATRGATIPPREDPTDSKIPWPRVLAELESDESDRDERWPAMTTEDAALKMRAFDALARRAGSGTGDAAATLEPRVARDVFLESGLPESVLADVYDAADEDGDGELSLYEFSCAMYLVERATRGCAPPPSASALPVETFASVRSAIERRRSKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK23</accession>
    <name>C1MK23_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_64179</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056315.1">
        <property type="nucleotide sequence ID" value="XM_003056269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK23"/>
    <dbReference type="STRING" id="564608.C1MK23"/>
    <dbReference type="GeneID" id="9681825"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64179"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="520"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="590" mass="66222" checksum="33A8E3CE4022C467" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKC1</accession>
    <name>C1MKC1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CYCA1</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_31383</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin AB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055968.1">
        <property type="nucleotide sequence ID" value="XM_003055922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKC1"/>
    <dbReference type="STRING" id="564608.C1MKC1"/>
    <dbReference type="GeneID" id="9681686"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31383"/>
    <dbReference type="eggNOG" id="KOG0654">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GAIRMKY"/>
    <dbReference type="OrthoDB" id="498396at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044772">
        <property type="term" value="P:mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20506">
        <property type="entry name" value="CYCLIN_AtCycA-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000013">
        <property type="entry name" value="Cyclin A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000167">
        <property type="entry name" value="Mitotic cyclin 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046965">
        <property type="entry name" value="Cyclin_A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0195">Cyclin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="124"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="7">
        <location>
            <begin position="217"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="221"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="341" mass="38856" checksum="BF679BBF9B311FE6" modified="2009-05-26" version="1">MSLLRTTQSFNYGDDSKQSREVFGELTNTTKYMGSVSQRSERRIGCTKNHAGVRKRNATPVKTAQNTWRDIDSMHSDDPLMCSEYVDDIYTNLQKSEVVLYPLSDYIEKVQTDISSTMRGILVDWLVEVAEEYKLSDDTLFLSVLYLDRCLSIRTVARSRLQLLGITCMLVASKYEEIYAPQVDEFCYITDNTYTREDVLSMERIVLDSLNFDLTHPTTKTFLRRCLSAAESDVKVDFLAGFLSELALLEYTFLRYSQSTIAAASVSLALMTLGRSPWSKTLEHYTHMFPCDLRECVQALHTCHLAAQQSSLSAVREKYSQMKFKCVSLIKPVDSCAEYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKW3</accession>
    <name>C1MKW3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_64664</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056066.1">
        <property type="nucleotide sequence ID" value="XM_003056020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKW3"/>
    <dbReference type="STRING" id="564608.C1MKW3"/>
    <dbReference type="GeneID" id="9681538"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64664"/>
    <dbReference type="eggNOG" id="KOG1154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NLAFPPH"/>
    <dbReference type="OrthoDB" id="409889at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009084">
        <property type="term" value="P:glutamine family amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd21157">
        <property type="entry name" value="PUA_G5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000006">
        <property type="entry name" value="Glutamate 5-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF3">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/glutamate/uridylate kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="10">
        <location>
            <begin position="204"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="323"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH59442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="354" mass="38324" checksum="1262A8CA00191EC9" modified="2009-05-26" version="1">MASIGMVRLMRMYDDFFTSVSQPIAQVLVSLDNLMDRTQYLNAQRTFQALLARDVIPIVNENDTIAVQDLKFGDNDTLSAHIASLTDADYLFLLTDVDGLYTGNPVNDPEATIIPLVENIEDLVVDTSDGAGTKFGTGGMATKIHAARLATASGCHTVVMHSNQLCHLTDIVINGASYGTLFLAVPQPLVGRKRWILLQKPADGQIVVNQKAEVALNNDKSLYGTHIISVAGSFTADEAVPLFITDSEGELREFGRAIVNYSSNECEKLIGQQSDDFFDIVGYSGAESVAHRNNICLWIPGGEEANLMDFPEINMETHPSVTDLNELLSEKPKTPPPFSTSGSASGDSPKAPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKW7</accession>
    <name>C1MKW7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64672</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056457.1">
        <property type="nucleotide sequence ID" value="XM_003056411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKW7"/>
    <dbReference type="GeneID" id="9681372"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64672"/>
    <dbReference type="eggNOG" id="KOG2933">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TMKDFGL"/>
    <dbReference type="OrthoDB" id="63891at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024395">
        <property type="entry name" value="CLASP_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567:SF62">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567">
        <property type="entry name" value="CLASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12348">
        <property type="entry name" value="CLASP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CLASP N-terminal" evidence="1">
        <location>
            <begin position="115"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="296" mass="33380" checksum="420E76C3B4E406CA" modified="2009-05-26" version="1">MINTEEEVTQCTGEIENNFSSRVEPRRVTVNQAGTRLPTGVEPEAIDVTVYYTRAEDLTPLHSPGCEATALLVQINSVNWTTVCSALTTARRLAIYHPNELKLVLDTVMPHLKLHIASLRSSVCKTALICATDFLKAFGELMFIHLQSGSPSLLAILLQKAALDKRFVMDEAKRTLSMMINAMPCKVLLNMLFLHVRDTNCKVRAIVAKYLTETVEKALCERERGIECCIDYNHEYLLQAVATFVNDRQPGARESARQLLSKLKDTYYHDTSSDEWFRFVERSLGKPTAIKILRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML85</accession>
    <name>C1ML85_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49474</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEBP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056514.1">
        <property type="nucleotide sequence ID" value="XM_003056468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML85"/>
    <dbReference type="GeneID" id="9681769"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49474"/>
    <dbReference type="eggNOG" id="ENOG502SFNB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AMYPPTQ"/>
    <dbReference type="OrthoDB" id="511660at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="entry name" value="Regulatory factor, effector binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="HEME-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220:SF58">
        <property type="entry name" value="SOUL HEME-BINDING FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="Probable bacterial effector-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="225" mass="24658" checksum="40BA9E4BD24B42A2" modified="2009-05-26" version="1">MATSSISIALTPASACPHAHPRRYPHRRQGSSTISLHRRSFSLLASTNRSNPDVPYQVLRVTDTYELRIYAAYYVACAPYSNREQGIASLMGYLEGGNERGTTFRATQPLVMRYVQNPEDKNSVGISSKTMELSLGKGVNNPPLSNQENVTVRIAGGELLAVVPFTGIATPELTARWRESLTSALIADGITLAEPGAFRLATYGQLYSLKPRLNELILHVKLPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLU4</accession>
    <name>C1MLU4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_38739</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056824.1">
        <property type="nucleotide sequence ID" value="XM_003056778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLU4"/>
    <dbReference type="GeneID" id="9682720"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38739"/>
    <dbReference type="OMA" id="WIACCAN"/>
    <dbReference type="OrthoDB" id="10563568at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="139"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="471" mass="52111" checksum="AAF17B9121F9A861" modified="2009-05-26" version="1">MPPCFNADADRAMMTQDARAEPEVAPEIVPAPPPRESDAREDVVAALAEALECEDKRLVRRFAATRAWDYDATMKLLREYVTWRKRVGLDDGSLCRAPGVRRELRKRHTMRLLNPKDARRRDRDADAAAAAAAANDEQRLTFLELHTPAMWPTACDVDGSPVIYTNMRQYQRGVGKAVENTFVWILETVCGEMDDAASAAAAAVPATLEGERADARDREMHGGKFTIFLDLSSCDHVPLHAFFSIGRVLQNAVKKGFRGRLRNVYVFPTGRGSRALLKILKPFLGKYTPPKVKLVPKEDKERLCEIFTRETLPPHLGGTSKLMAVDLEAEAAEEDVAAAAAAAAAVAPGAAASDADGDEHHHEDLKWFLKVPAFNFVVLVAMTAHCATHGPTFGRAARDEKAKEKFETDDGDVRRARLRRYLAPVVRNSVMWHLIGREGLGIKWSALWSAGVTVFFGIVRRFTSAEGRGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM93</accession>
    <name>C1MM93_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_62412</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057361.1">
        <property type="nucleotide sequence ID" value="XM_003057315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM93"/>
    <dbReference type="GeneID" id="9682332"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62412"/>
    <dbReference type="OMA" id="SGWDEAP"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33734">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING GPI-ANCHORED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33734:SF22">
        <property type="entry name" value="MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="54"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="264" mass="28011" checksum="E20437E375280435" modified="2009-05-26" version="1">MNALTTSATTLKSVALTAKRASRGVAVSSRAATTTPRRGARLCVRAAARGGGPSVYVVQKGESLWSIAQKQNVSLEELQRVNYNALGGKDVIYPGQQIVVPGAAARGPSSGGRMPAVPAFAKPTPSSGGRSSSYAPSSSSSSSTSYSSYSSYAPSKAAALPAPRAAKNGSLVTAGAFFLALAVGIYIFKQDDVPATMRFDESQGEGYGDDQYYDEQQYNQQYDQQYDQGYGQQQQGYGQQQQQQRGEWGGAQQQGYGSPPEWNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMD7</accession>
    <name>C1MMD7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56491</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056912.1">
        <property type="nucleotide sequence ID" value="XM_003056866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMD7"/>
    <dbReference type="STRING" id="564608.C1MMD7"/>
    <dbReference type="GeneID" id="9682825"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56491"/>
    <dbReference type="eggNOG" id="KOG0531">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WKIEMAE"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040091">
        <property type="entry name" value="LRRC56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22708">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22708:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="254"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="342"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="392"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="557"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="607"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="363"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="505"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="521"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="563"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="649"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="696"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="733" mass="75409" checksum="D55202FEBFE9FEA1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNP7</accession>
    <name>C1MNP7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55984</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057146.1">
        <property type="nucleotide sequence ID" value="XM_003057100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNP7"/>
    <dbReference type="GeneID" id="9682585"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55984"/>
    <dbReference type="OMA" id="REHANAH"/>
    <dbReference type="OrthoDB" id="248222at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="372" mass="39514" checksum="438B084217A7F479" modified="2009-05-26" version="1">MCDGGVRERCARVVQCPPPGAGQPIASERQRPFLNRAVRDEKGRCPAPTDDGRGIRDVEDADTAPRVTTPSPHAAAAMSAAQPPPAQVKNALGALKKQRSENRSHRRSLSGGTLDLSPEALAAPMKAMHVGGSRGASPSPASSPSTSPTGTTMTAHEKLKAASKHRRLSNGRASPTPYDLHASGDADAKARDVGDGKSPTSSASGPAFEWLLRRQMEVEMMFRGEKPATWRQCDVVRVRDVVARFAAFFVDLHAAAASLPGASASSNRFGVGGGGGGEPSSSCAPSTLFQELLHRVSGVNAGRSMDEQKREGNVPMHQAKVLDRRHRTNDECAGMDESLGRERVMNLVASVKARSIVHWSPYGRVRVVNANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNT7</accession>
    <name>C1MNT7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56026</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056702.1">
        <property type="nucleotide sequence ID" value="XM_003056656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNT7"/>
    <dbReference type="GeneID" id="9682607"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56026"/>
    <dbReference type="eggNOG" id="ENOG502SS1E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2019034at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="450" mass="48916" checksum="BD8B20666203BF29" modified="2009-05-26" version="1">MAAGRGAPAALPDDAELLAILRADPRLASVLEDPERYRLQVLLTEVAPASDGDGDDDGAHSAPCEATTTTTTTRTTTTRATLRRRAYRADAEYFYPASAVKIYGAVVALFQLQLMASQGVAVVELDTPLAFESRTAPVAASNDAPPPKSAAAPPLGCSAPTTMRREISALFHVSDNEAFNRCYDVAGRTLMWEWANSESLNPPFRGPRILHRLFSEAKGTDDGGSFPGVWARVGRDGDEDAWRRVLCRRHDVCGHLVGDAKRESVGKAHVAADGTVVDEPLDCSARNRASLASLQDTLIRLTRPEFDESNFKLTETHRRFVLAAAAGSPRDSPDPSARDDAATFPNNYNKFFVDGVTRAVGGDGSRVRITNKCGQAFGFSVDNAFVEWIGGGEDEDENRNKNPFYLAAAIETNANGVVNDDVYEYADVAEPFMDALAETVARWVWREREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNZ1</accession>
    <name>C1MNZ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_56082</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057196.1">
        <property type="nucleotide sequence ID" value="XM_003057150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNZ1"/>
    <dbReference type="GeneID" id="9682635"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56082"/>
    <dbReference type="OrthoDB" id="2384430at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="144" mass="16703" checksum="B5EDE90F1C73E131" modified="2009-05-26" version="1">MRTRSRTGFNVIPENCAAVVFSHLGDDPRDRIALAQVSRVWRDAERTDASLPVAPSALIELAHDVGKQQYHELYWMSKAADLGDAEAMYWLGRFFEGRADEIEEYEEQTWMLYLTKAYQWFERASECGHAEASELFRRRRVSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP15</accession>
    <name>C1MP15_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="14">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MICPUCDRAFT_46639</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the BRE1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="14"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056742.1">
        <property type="nucleotide sequence ID" value="XM_003056696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP15"/>
    <dbReference type="STRING" id="564608.C1MP15"/>
    <dbReference type="GeneID" id="9682645"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46639"/>
    <dbReference type="eggNOG" id="KOG0978">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CEEEIAG"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033503">
        <property type="term" value="C:HULC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 14 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="785"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="91"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="274"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="706"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="357"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="707"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="719"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH58387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="837" mass="89003" checksum="7F042ED48F0142F6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPT4</accession>
    <name>C1MPT4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RHOMBOID-like protein</fullName>
            <ecNumber evidence="10">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_39188</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serine protease involved in intramembrane proteolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="10"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057639.1">
        <property type="nucleotide sequence ID" value="XM_003057593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPT4"/>
    <dbReference type="STRING" id="564608.C1MPT4"/>
    <dbReference type="GeneID" id="9683445"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39188"/>
    <dbReference type="OrthoDB" id="497508at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002610">
        <property type="entry name" value="Peptidase_S54_rhomboid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936:SF69">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936">
        <property type="entry name" value="RHOMBOID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="12">
        <location>
            <begin position="207"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH57590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="350" mass="37286" checksum="D83E7C6F0DF1A9E6" modified="2009-05-26" version="1">MAHARVARPGVALVTSSRARGRLSRARATTPRVFAPRSQRRRAARVGASADDRDGDAVGPIEDADDVLRALDSVLGVSAAEVAADAAREREEEEAAAEDKRRRLEAAAAADAKKKRAEDVADEASADDDDDDDDDDDADADPPPWLWWSDRALYDVPTVFPTAALTFLALHLVVFVGDYALYAAGVGNGGDLFLRVAEVDDAVITYSQWWRPFTSCLADYGLVHFAVANLGLIVIGLEANAVLGTWPFVAIYVLSGAVGSLVTTATDADTNLTVGGGDALLGVVGAMCVYILINVEPDWNRAGCYTRCITMGVVATALLWLGGMPTIGSEHVVRRVFSRYTGSRTIAFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQD4</accession>
    <name>C1MQD4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57249</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MDM20/NAA25 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058109.1">
        <property type="nucleotide sequence ID" value="XM_003058063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQD4"/>
    <dbReference type="STRING" id="564608.C1MQD4"/>
    <dbReference type="GeneID" id="9683175"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57249"/>
    <dbReference type="eggNOG" id="KOG2053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAQDMRR"/>
    <dbReference type="OrthoDB" id="1874341at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019183">
        <property type="entry name" value="NAA25_NatB_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF3">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09797">
        <property type="entry name" value="NatB_MDM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1060" mass="110662" checksum="10C2AAD46B4A785C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR47</accession>
    <name>C1MR47_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_57523</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058240.1">
        <property type="nucleotide sequence ID" value="XM_003058194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR47"/>
    <dbReference type="STRING" id="564608.C1MR47"/>
    <dbReference type="GeneID" id="9683307"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57523"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="383" mass="42825" checksum="9852272B1D6875BF" modified="2009-05-26" version="1">MAAPPVPDPIDRRNLSVAFEDANPALAGQTFAPTPTAPTPTRTGMFRSDAISNDPAAYVGRELRPRNSAYTPIATRTTNGDLMGWKQPEVQPAPEPRKWESTGLKFTQRESTTTNALYPRYEVTPEKPPPRKEWQPNGLKFTDRSQTTSNQLMPGYAPEPPEVNEARKWEPTGINFVQRSSTTNNQMFQKPEMHVELPPPRKEWLPNGLKFTDRSQTTSNQLMPGYAPEPPEVHEARKWEPTGIKFTQRESTTNSQLFKPPEVKLFKPVGIAVEDDKVQNLLHGDHTPPCSVSRSFTTTRTGQTEVAIRLVRGWSKYASQCEHLCVLDMDNIPPGPPGKQEIVVTVSMDKNGKLFAEVKDVHSGMTDTWSEYDGVEDYPEGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR69</accession>
    <name>C1MR69_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_33182</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This protein binds RuBisCO small and large subunits and is implicated in the assembly of the enzyme oligomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Oligomer of probably six alpha and six beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057879.1">
        <property type="nucleotide sequence ID" value="XM_003057833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR69"/>
    <dbReference type="STRING" id="564608.C1MR69"/>
    <dbReference type="GeneID" id="9683317"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33182"/>
    <dbReference type="eggNOG" id="KOG0356">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MKIVMAG"/>
    <dbReference type="OrthoDB" id="1733909at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009488">
        <property type="entry name" value="PRK12850.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009489">
        <property type="entry name" value="PRK12851.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00058559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00062746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="593" mass="62800" checksum="838F8D290620E5D9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRG4</accession>
    <name>C1MRG4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome b6-f complex subunit IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PETD</name>
        <name evidence="14" type="ORF">MICPUCDRAFT_44239</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Thylakoid</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058303.1">
        <property type="nucleotide sequence ID" value="XM_003058257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRG4"/>
    <dbReference type="STRING" id="564608.C1MRG4"/>
    <dbReference type="GeneID" id="9683741"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44239"/>
    <dbReference type="eggNOG" id="KOG4663">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KKGMGHN"/>
    <dbReference type="OrthoDB" id="244at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042651">
        <property type="term" value="C:thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00290">
        <property type="entry name" value="cytochrome_b_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.980:FF:000001">
        <property type="entry name" value="Cytochrome b6-f complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.510:FF:000002">
        <property type="entry name" value="Cytochrome b6-f complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.980">
        <property type="entry name" value="plastocyanin oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01344">
        <property type="entry name" value="Cytb6_f_subIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005798">
        <property type="entry name" value="Cyt_b/b6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036150">
        <property type="entry name" value="Cyt_b/b6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005870">
        <property type="entry name" value="Cyt_b6/f_cplx_suIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048260">
        <property type="entry name" value="Cytochrome_b_C_euk/bac"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01156">
        <property type="entry name" value="cytb6_f_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19271">
        <property type="entry name" value="CYTOCHROME B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19271:SF40">
        <property type="entry name" value="CYTOCHROME B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00032">
        <property type="entry name" value="Cytochrom_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000033">
        <property type="entry name" value="B6f_17K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81648">
        <property type="entry name" value="a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51003">
        <property type="entry name" value="CYTB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b/b6 C-terminal region profile" evidence="13">
        <location>
            <begin position="64"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH58254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="159" mass="17364" checksum="6A0D23F3CACF7223" modified="2009-05-26" version="1">MPVAKPDLSDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIALSIGLAVMEPTMLGEPADPFATPLEILPEWYFFPTFNALRVIPNKLLGVLSMAAVPVGLITVPFLESINKFQNPFRRPVATSVFLIGTFYAIWMGIGATMPIDKAISLGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRN2</accession>
    <name>C1MRN2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Protein disulfide-isomerase</fullName>
            <ecNumber evidence="4 12">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_44321</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4 12"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058538.1">
        <property type="nucleotide sequence ID" value="XM_003058492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRN2"/>
    <dbReference type="STRING" id="564608.C1MRN2"/>
    <dbReference type="GeneID" id="9684343"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44321"/>
    <dbReference type="eggNOG" id="KOG0190">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HRTQDSV"/>
    <dbReference type="OrthoDB" id="494975at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02995">
        <property type="entry name" value="PDI_a_PDI_a'_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000107">
        <property type="entry name" value="Protein disulfide-isomerase 5-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005792">
        <property type="entry name" value="Prot_disulphide_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01130">
        <property type="entry name" value="ER_PDI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF132">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005124869" description="Protein disulfide-isomerase" evidence="12">
        <location>
            <begin position="25"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="13">
        <location>
            <begin position="6"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="13">
        <location>
            <begin position="375"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="56"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="426"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605792-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH56993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="513" mass="57151" checksum="8F41BB621CCC13E3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRS6</accession>
    <name>C1MRS6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68277</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058561.1">
        <property type="nucleotide sequence ID" value="XM_003058515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRS6"/>
    <dbReference type="GeneID" id="9684000"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68277"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="199" mass="22332" checksum="07EC045973C2F7ED" modified="2009-05-26" version="1">MYAGVGVHRDVRGATVQLERALERSQDASEAFAPLMALIGLRCSHFVENVVASAREASTRAYRVYRFFKRPEEPWKAMRRKDPPAPARDAEKARLKEANARALNERDRKATRRSDPRRLQPVFRSTEDAVLVVLCACVVLLLYTRFVVMRRYETLASRGARREDAGWIGAQILYAGAGLACAVAILIGITVYDFAVSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSA8</accession>
    <name>C1MSA8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Threonylcarbamoyl-AMP synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_5503</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059019.1">
        <property type="nucleotide sequence ID" value="XM_003058973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSA8"/>
    <dbReference type="STRING" id="564608.C1MSA8"/>
    <dbReference type="GeneID" id="9684458"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5503"/>
    <dbReference type="eggNOG" id="KOG3051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PLTQGWE"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="Sua5-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052532">
        <property type="entry name" value="SUA5_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42828">
        <property type="entry name" value="DHBP SYNTHASE RIBB-LIKE ALPHA/BETA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42828:SF3">
        <property type="entry name" value="THREONYLCARBAMOYL-AMP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="2">
        <location>
            <begin position="21"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="245" mass="26361" checksum="BCC8BA6A63298D7D" modified="2009-05-26" version="1" fragment="single">PRAPSQSKTLFVTVEPDASDDWRLDEIADVIRGGGVGIIPTDTKYAFVADLESRDAVQTLYRLKDAGVGKPMSVLVRGFSDIDAYTQGFPDNVVAGRTQPFKLARQCLPGPYTFILQAGKAMPKICLQDPSTKSKSCKARKTVGVRFSADPVCRALLSRLDRPLLASTVPCEVDGDGIEYAQDPAVMCDDYESEGLLAFVIDCGVRENPPSTVIDLSGGAAKLLRRGAGDASAWVEDDEEETLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSC0</accession>
    <name>C1MSC0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_68414</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059026.1">
        <property type="nucleotide sequence ID" value="XM_003058980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSC0"/>
    <dbReference type="GeneID" id="9684465"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68414"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="499" mass="53754" checksum="E9098D26BE793D38" modified="2009-05-26" version="1">METLKDTCCEDSVRLTSPGLPRRGRGGVDGGDAGLSTAVCGLRAGLAGPWARRLGEALPALTRKLIESGAPQPAVNKFAYNATLLAWVVASDQTPKASPNCVGISNFTYYPPIHAMRANPREEATLGESPYGDAEYDYGFTTSPPRSETSGEALSKRDEFFLQEGLLAPPAALGLRASSIKEMHEVLKDVTVWARDCVCARLTKPSDPVNIWNKELFTALAAAQDFVKMFEQEAMRSRSVATLVCVTMLLKQVNERRGKERARLLGGRLKDCDPESELHDYDDRLRDGVRFEVLRTLESHDAIFVPGRRAGELPTFGLWETPGTTEDATQPIKIATSFPTIRYGDSDRPTARIIDVNPTVSVWSIVEEYGSNGDSAYHLYARASPVAAAMHHVLNAIAAAVEHIKTAAWISTGSSSYGDAAAHDAVRTALTAGGASSSSSPLRSLIVAFGVIHAAAVALRVAAPPVDVPEDVVSPYPAKEVRSIHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSF2</accession>
    <name>C1MSF2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_47422</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058668.1">
        <property type="nucleotide sequence ID" value="XM_003058622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSF2"/>
    <dbReference type="GeneID" id="9684483"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47422"/>
    <dbReference type="OrthoDB" id="553254at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="8">
        <location>
            <begin position="132"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="562"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="651" mass="68148" checksum="5A6B3E2D80BFB36B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSG2</accession>
    <name>C1MSG2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58473</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058674.1">
        <property type="nucleotide sequence ID" value="XM_003058628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSG2"/>
    <dbReference type="GeneID" id="9684113"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58473"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057039">
        <property type="entry name" value="At5g52880_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24104">
        <property type="entry name" value="At5g52880_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="180"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="382" mass="40404" checksum="0E5B09860E67721A" modified="2009-05-26" version="1">MPRDRGGGGLAPRRRRATEFGAPAAGAKGDGVVASRSRYESLAISRGLARHANDDPHREEAFTRAALELAHVLRACYASSSKDAREAMTRDAIAGASRAAHLATSRQLAASHALRRAAVATLPSKRREAFERAHAAAAVTRARDAKKRRARAAEAEAEAEAEEEELDDDAPDDAASPTTTTRARDLPDDVLRAVFDRLNPWDLGRCAATCARWRALVAGAERAWKRGCEDAATTAAAAERTRSALGDAASWRDAFVALVATSTSTSTSRAGARDGGRRTAPAIAEPSGRAWCERCETYRWTWDDGGDGGVAWPAGHRDSHRVRTGAMGAAFVVDRVLGGGGDGDSDSDSDSDSDSDSDGGGGGGGEATDVARRMRLWRIRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSX0</accession>
    <name>C1MSX0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_8378</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058755.1">
        <property type="nucleotide sequence ID" value="XM_003058709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSX0"/>
    <dbReference type="GeneID" id="9683790"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8378"/>
    <dbReference type="eggNOG" id="KOG1153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="640735at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="6">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="154" mass="15310" checksum="C00248E06B6B6482" modified="2009-05-26" version="1" fragment="single">HGTHVASVATGFGLGVARCATTHPVRVFNADGRGTTARVLDGLRWVADRVKNGTSGGALRPAVALLSIGGTRSSVLNAAVDALSDASDVVVVVAAGNQGEDACAHSPASSRRAIAVGAVDATDRRLGFSNYGPCVDVFAPGTDVRGAVSASVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSZ0</accession>
    <name>C1MSZ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_57876</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058404.1">
        <property type="nucleotide sequence ID" value="XM_003058358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSZ0"/>
    <dbReference type="GeneID" id="9684205"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57876"/>
    <dbReference type="eggNOG" id="ENOG502S1N3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EYDKIRW"/>
    <dbReference type="OrthoDB" id="525072at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="166" mass="19463" checksum="1BED2C3F7B680A40" modified="2009-05-26" version="1">MVKINDPTEKEEEEKKDWTHAYAEDLRADIYTEVNPSPKATVHQREWRKILNGDPVEINPSVGAGLKVMTINEWSSRWKQNDRFPDCLACQSVSTKEHHFTQTWCRGKRQFESELLCSDCHMFSWRSYSDPDFMLPEEYDKIRWEKMVEAKATGKPIVRDSAKAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT97</accession>
    <name>C1MT97_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosyltransferase family 64 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_16819</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 64 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058826.1">
        <property type="nucleotide sequence ID" value="XM_003058780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT97"/>
    <dbReference type="STRING" id="564608.C1MT97"/>
    <dbReference type="GeneID" id="9683890"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16819"/>
    <dbReference type="eggNOG" id="KOG1022">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CEDIGLN"/>
    <dbReference type="OrthoDB" id="5954868at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015338">
        <property type="entry name" value="GT64_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48261">
        <property type="entry name" value="ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48261:SF2">
        <property type="entry name" value="ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09258">
        <property type="entry name" value="Glyco_transf_64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase 64" evidence="6">
        <location>
            <begin position="51"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="37618" checksum="A4EF229AAD0FA789" modified="2009-05-26" version="1">MWAVTGDLTSRIGSDCAPPTRGAETTISKTALRELAYEGDSTVAGEDDRQFTLLLNTFKRRDLLKRAIKHYLSCDDVGEIRVVWSEPDPPPDPTDRDARLYYGDDPSKEVRYQRHPTTSIQNRFEPPSAGVDGDATSGKLKHTAVFNVDEDVRLPCKALTRGFDAWRANREQLVGFYPRNHVRSDRGCGYRYAWNDLELWRGGEFSIILTKAAFMHAKYLNTYSKGLPREAREYIDRRKNCEDIAMQILVTKTTGIPPVYKALPMFYYVWAKLGGIGVPGISKNAGHHDERGACVTDLSRMIGAEAPGTDTPLLRAPLKEWRRHAPGSIRAWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTL6</accession>
    <name>C1MTL6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68202</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058514.1">
        <property type="nucleotide sequence ID" value="XM_003058468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTL6"/>
    <dbReference type="GeneID" id="9683953"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68202"/>
    <dbReference type="OMA" id="AYFAMER"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="426" mass="46656" checksum="D7DCD2142654A101" modified="2009-05-26" version="1">MTSAAPALAPHLAMEAARRPHAARRLGMNVPQPAVQRFDVPRVAEGDLQVRALELERRPKAARRLGYVASFAEPRGAYIPDNWRINLSRRFFFRSLRLTLPLLPPADVPTMSAQDTNYYKMEVDRRHRAAKRIGEVRYLSVDVTEPTAFAPLPFARTAAALMEIERRPKAARRVGTFRAPALADAPPPPAMAAMDTAAFAMEVSRRRVAARRSGIVKLPRRASPRNLPSVDVADTAFYDMELDRRPRAAARLTTKASGPTSAPLDAFAELSKIAADDLMKRRAPSAFDDASFDKSNPSRGASATAPNPFASLERMLESTLDISGSKSRGSSLRGADNFNTTATGGGVRRQNSSTHLRRVGSNASMGVNNVVQHRPGRHVHCDEEGESGDVVCVLYGADDEPEDVVMTVPREQLEEQMRRMAAATSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTR1</accession>
    <name>C1MTR1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58516</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059362.1">
        <property type="nucleotide sequence ID" value="XM_003059316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTR1"/>
    <dbReference type="GeneID" id="9684552"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58516"/>
    <dbReference type="OMA" id="WSCMLEG"/>
    <dbReference type="OrthoDB" id="496751at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="342" mass="35700" checksum="70AD602C382A72DE" modified="2009-05-26" version="1">MPNDDDRRKCAPDPTAAREVVVEDGFKYKKRKSAAPGAAAAAPAPAPAAAPAGGVIHASAVAAAGGGPVGPGPAPTPADDLPDDYPGFHIHDKIPTDLPEDERFQMLIEEICEMQCKEEKARLIAEHGAELGTKIAKQLEGALSEFQLKVEEMVVRGDIKFGPGGDGDGDGDGDGVGDALLDVRDAKEEAMTAVMTQLENELEQWNEIEKQVAEEGSGPSEAEEALAKVDAEEAMNAVKVLMEAEAAATAAGTAGEGEAVVIPGHLREAVEEAKRKLGMQAEGLTALCDGVEALCVRAERACEVFSGALAENDFKGLPHVNSPHNLIKSLVASKKAEKDEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTS9</accession>
    <name>C1MTS9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58538</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059371.1">
        <property type="nucleotide sequence ID" value="XM_003059325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTS9"/>
    <dbReference type="GeneID" id="9684518"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58538"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="85" mass="9245" checksum="F8AC03803164F900" modified="2009-05-26" version="1">MSSMNDYFRSSKSSTPPNSAGKTVTHGPVPPAPKKKAPTRSRVGDPELDATKRRLDFIDDDDDDDAAEREGNETRAVADAPTTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTZ1</accession>
    <name>C1MTZ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58608</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059104.1">
        <property type="nucleotide sequence ID" value="XM_003059058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTZ1"/>
    <dbReference type="GeneID" id="9684846"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58608"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="322" mass="34466" checksum="E40C08B618CC773D" modified="2009-05-26" version="1">MSRAWTTRPQRAPPPRAAMPPLGGGGGGATPTPTPTPTSSSLDVFRLLVPELATRALTPSVVRGVASDARAIVRVDRVHGVHERIVLVADDDAAARRETRERGRGRGVEREEPTPAQRALLALHQLASARALALAPRAPPPPLRLLLTRREGAWLRERGVVAWARDVAGAAVRAYAAAAAAAAAEDEVLEIGAWPPLALGAALRAVTTGLLTMREEERDVDAAAVRVPRRFEFGFEFAPPRGVPPGFRPVPPTPPRGPAERAVTDHLRVAVELVATGVIGKKGEHLTRVRNTSRAKVWSFGVRVRGWFSPAAAPFLFDFAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUE4</accession>
    <name>C1MUE4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_49622</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059180.1">
        <property type="nucleotide sequence ID" value="XM_003059134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUE4"/>
    <dbReference type="STRING" id="564608.C1MUE4"/>
    <dbReference type="GeneID" id="9684620"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49622"/>
    <dbReference type="eggNOG" id="KOG3406">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAEHQIP"/>
    <dbReference type="OrthoDB" id="10249311at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000019">
        <property type="entry name" value="40S ribosomal protein S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000530">
        <property type="entry name" value="Ribosomal_eS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047860">
        <property type="entry name" value="Ribosomal_eS12_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11843">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00972">
        <property type="entry name" value="RIBSOMALS12E"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01189">
        <property type="entry name" value="RIBOSOMAL_S12E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="6">
        <location>
            <begin position="28"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="144" mass="15711" checksum="F4794F76C29AE368" modified="2009-05-26" version="1">MAEEEEPVVMEETAEEAAAEEPMDLMSALQMVLKKALAEDGLHRGLREACKAIESRKALLCVLAQDCDQADYTKLIQALCNEVNVHLIRVPQAVQLGEWAGLCKLDAEGTARKVVKCSCVVVSDYGEETEGLAMLQEFLKNASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVA6</accession>
    <name>C1MVA6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59121</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059341.1">
        <property type="nucleotide sequence ID" value="XM_003059295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVA6"/>
    <dbReference type="GeneID" id="9685074"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59121"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="221" mass="23545" checksum="338767371648F5FE" modified="2009-05-26" version="1">MPPESALASSRESADDWVSGPFDLSGDDDDGASTDDRESADDARVPDRSIDRPERASPASRAANAADAAFDDDAGARAWMALCEEAMTGGFREREAWDDETTALLSRARRLARGGVRGEKAEEGKEKDDDDDDGDDDDDDGDDDAARPAREDENARRRSVSNLLRPQNIPPSAALVLVGVLLGVLLGVFAASTNAVPASSRSPSLRRVPRHTGPHTTAFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVC5</accession>
    <name>C1MVC5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_59142</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059644.1">
        <property type="nucleotide sequence ID" value="XM_003059598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVC5"/>
    <dbReference type="GeneID" id="9684790"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59142"/>
    <dbReference type="OMA" id="NMQFGAN"/>
    <dbReference type="OrthoDB" id="10674457at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="578"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="432"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="691"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="630"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="726" mass="76472" checksum="AA722C28B295F85F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW23</accession>
    <name>C1MW23_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59596</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060139.1">
        <property type="nucleotide sequence ID" value="XM_003060093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW23"/>
    <dbReference type="STRING" id="564608.C1MW23"/>
    <dbReference type="GeneID" id="9685290"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59596"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="123" mass="13165" checksum="B90E622ACE474870" modified="2009-05-26" version="1">MLTADNLAIITEGDDRGGGGEGGPGSDDDSEGEWEEYDEDGDDGEGDGEGGAAFGEEWRQNIRRKGETPEEKRARKAAVKAGRRDARAAKKGLKQTFKQEEREMGKKQGAGDVRAGLSVRPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWJ6</accession>
    <name>C1MWJ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40749</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060229.1">
        <property type="nucleotide sequence ID" value="XM_003060183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWJ6"/>
    <dbReference type="GeneID" id="9685373"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40749"/>
    <dbReference type="OrthoDB" id="406368at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40429">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40429:SF1">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="430" mass="45385" checksum="8BA45095859AC467" modified="2009-05-26" version="1">MDVEAPPTPSADAAVAANDANANANDTITPRDPLLASDASKLSMRTSPSAFAGERASMQRSQFGEQVEAGKRTSPSVGFATASRFPWLEKPDSPKAPRPPSYAVPGPGAYAPAAAVGDQARSDRLIHHAGSRTTAFTLVPIRPRRRGERRSLRTFSPGGHFSPHRVPRFQSRHTAMPFNSASDAFRLHPDVASNDALNDPPQILAERRTCPRAAFGKAHRFATAPKRNRAPDPGTYPLPPSLGKQPDSTKETGATISFTRGSREVSSGAVEAGRDAPPSTRYTLKDSLTNSPYKSIAFTRDKRAIGDGAKKRADERDGGSGPGPGAFRAERSVGPQTRSGRRRAPSASFGTCYRDQAAKASLSREQASAILGGRMGPGPAVEPPGPGGLGAQIRSARRSAPSVGFTRGKRFGKGEDAGKVDTPGPGSYRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX43</accession>
    <name>C1MX43_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68992</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060625.1">
        <property type="nucleotide sequence ID" value="XM_003060579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX43"/>
    <dbReference type="GeneID" id="9685772"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68992"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910539" evidence="1">
        <location>
            <begin position="34"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="123" mass="13317" checksum="56B14DF85F32194B" modified="2009-05-26" version="1">MMRPSSPASTIKALVLALVVVLALSSAPLPVEAASVRVVPFSFEVGLSGLSVRSFTPWVRRDLCLAYTNFLKIDRKVRAPRASPLARWIRPQPRTPSESATPCSLFLPTTSTHSFSAHVSALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXE1</accession>
    <name>C1MXE1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_40950</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060678.1">
        <property type="nucleotide sequence ID" value="XM_003060632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXE1"/>
    <dbReference type="STRING" id="564608.C1MXE1"/>
    <dbReference type="GeneID" id="9685817"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40950"/>
    <dbReference type="eggNOG" id="KOG1864">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANFGNTC"/>
    <dbReference type="OrthoDB" id="27652at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02663">
        <property type="entry name" value="Peptidase_C19G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF733">
        <property type="entry name" value="RE52890P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="6">
        <location>
            <begin position="23"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="376" mass="41723" checksum="59E32CE25E73D7D2" modified="2009-05-26" version="1">MGNSANKLEKAFAGDIPDGERYFGLENFGNTCYANSVLQALYFCQPFRDRVLRYHAELAKDHEENLLTCLGELFASIAGQKKRTGVFAPKKFIARLKKDNELFRSFMHQDAHEFLNYVLNECVEILEKEHRAAHPTPAGASAPPITTWIHDIFQGQLTNQTRCLWCENVTSRKEAFLDLSLDVEQNASVTSCLRTFSSNETLDSADKFQCDACGGLQEAHKRMLVKTAPPVLAMHLKRFKYIESLGRHKKLMHRVVFPDELKLNNMEDDLPGTPDAAYGLFAVVVHVGSGPNHGHYVCLVKSHGQWLTYDDDDVQLADASALQNVFGSTREHGGSNTEHGYILFYAREDVAGGGMGGVGLGRPGVAGRMAAALRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXV6</accession>
    <name>C1MXV6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60305</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060763.1">
        <property type="nucleotide sequence ID" value="XM_003060717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXV6"/>
    <dbReference type="GeneID" id="9686200"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60305"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912140" evidence="2">
        <location>
            <begin position="27"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="267" mass="29068" checksum="1B47639B77D48950" modified="2009-05-26" version="1">MRARVLNIAFALLALAILRASTPADAFNANYVNELSTAHAEEGYRDGGGGSGSGGEPKRVKIPVSTRGHIPDDWYSGEKSMDLHVGTLTVRRADATRGDARSLARSIGRSIDRSSPRRDSIPTRTVLPFPSSQRSPPPSPQPTRPRIPQEEEKSDLHTPRHWRCNSCQGVAHTITRRLRAATTTDATDPTINLTTPRRLTEAEAIDVVEKTCADAADEIWTAYGSIGLASGINFFFGPGVEPPPREEQARSTHWTPYDRVGVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY46</accession>
    <name>C1MY46_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47984</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060807.1">
        <property type="nucleotide sequence ID" value="XM_003060761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY46"/>
    <dbReference type="GeneID" id="9685943"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47984"/>
    <dbReference type="eggNOG" id="ENOG502QVM2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PGRSEYA"/>
    <dbReference type="OrthoDB" id="498529at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47876:SF2">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47876">
        <property type="entry name" value="OS08G0260000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="265"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="363" mass="38382" checksum="FC6BF9088312C140" modified="2009-05-26" version="1">MSHAASTRCPLASRHALLGRARSSLGASSSAAAAAAAASPRPLAAGVSSRRRQTPRPPVSRSRAPTRCVSTPERSAKDPRARVALDPSVVAVRETTTSGELRASAAARALSFYEYPPDRSEYSVRAHRNMRIDAEWDAIGEKIAGTDVAFKNCRVSCLVAALPLLEDGAAPEGFGIDDGVHPASVARDGDPPPGTIVLGTLDVNQGVTLPAEELAGKFPRDDDPVRPGTDTSQDGRGPGEEKKKKTQTGDTGDAGAGETGVRATRYRRAYLSNVCVLPQARRLGLGKRLMRRAMEVAEGWGVEEMYVHVVSDNHGAKSFYEDFGFVVESEETAAFAAGLSRPPRIILRKSVGVEGASAEEASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYA9</accession>
    <name>C1MYA9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_18858</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060250.1">
        <property type="nucleotide sequence ID" value="XM_003060204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYA9"/>
    <dbReference type="GeneID" id="9685692"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18858"/>
    <dbReference type="eggNOG" id="KOG2508">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YWHDMEF"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF99">
        <property type="entry name" value="BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="148"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="345" mass="38689" checksum="5BA24A2B07563BBA" modified="2009-05-26" version="1">MSSDADDDNGDPRDARDLFKWLSREVRDLSCARAVPRVDGSGGVDALAFLRDHVARNSPCVISNAIDHWPALTRWKDPSYLADVMGDAVVSVNVTPNGRGDALLDTDGWRVFVAPEERRETFRDFLRELNDDSRRRGDDSHPPVVRYISKQCGSLLDEFPALTRDCERELEWATAAFGAPPDAVNLWCGDDRAVTTFHKDHYENVYCVVTGTKTFALLPPCDGARLKPREAPAATFEDAPRNRFALRLERPARSVAWSSVDVDDLARDGYPPPLLVDVHAGEILYLPALWHHRVSQRRGKDGEPCAAVNFWHDMAFDDRHACARFLDEARARFEVATDPTETSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYL2</accession>
    <name>C1MYL2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Microtubule end binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">EB1</name>
        <name evidence="14" type="ORF">MICPUCDRAFT_68917</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
            <location evidence="8">Cytoskeleton</location>
            <location evidence="8">Phragmoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAPRE family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060294.1">
        <property type="nucleotide sequence ID" value="XM_003060248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYL2"/>
    <dbReference type="STRING" id="564608.C1MYL2"/>
    <dbReference type="GeneID" id="9686025"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68917"/>
    <dbReference type="eggNOG" id="KOG3000">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WIKRFWD"/>
    <dbReference type="OrthoDB" id="2119228at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009524">
        <property type="term" value="C:phragmoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009652">
        <property type="term" value="P:thigmotropism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000028">
        <property type="entry name" value="RP/EB family microtubule-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004953">
        <property type="entry name" value="EB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036133">
        <property type="entry name" value="EB1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027328">
        <property type="entry name" value="MAPRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10623">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03271">
        <property type="entry name" value="EB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140612">
        <property type="entry name" value="EB1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51230">
        <property type="entry name" value="EB1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="12">
        <location>
            <begin position="15"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="EB1 C-terminal" evidence="13">
        <location>
            <begin position="187"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="122"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="306"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="154"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00060413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH55063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="359" mass="37753" checksum="E3E5002FD994C2D7" modified="2009-05-26" version="1">MANASSIGLQNPAFFVGRAELLDWVNGLLNLRLTKVEQVASGAVHCQILDACHPGVVNMSKVNFDAKSEYDMVNNYKTLQTVFDKLKITRMIEVSKLVKGRPLDNLEFLQWMKAYYDTATGGVRPEDYDGEERRACSKGGKKASGGGGGGGGAKPAASRPAASRPAASTASKPASTASKPASTASSTAAANAAAVKELTAECAELKLAVERTEQEREFYFEKLQDIEFLCQRPEFASQTLAKVVEKILYFTEGKPDVEAIIAECGEEAAATAAAAAAPSPAEPLSTPATEDDLDTTVEAVVENMESLTVAPETETETETSEAAASDAPTATLSDSPLCTQLSGDLSGSADRSPLAEVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYP0</accession>
    <name>C1MYP0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_19397</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060308.1">
        <property type="nucleotide sequence ID" value="XM_003060262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYP0"/>
    <dbReference type="STRING" id="564608.C1MYP0"/>
    <dbReference type="GeneID" id="9686039"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19397"/>
    <dbReference type="eggNOG" id="KOG2049">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HITRILH"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000237">
        <property type="entry name" value="Pumilio homolog 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF13">
        <property type="entry name" value="PUMILIO HOMOLOGY DOMAIN FAMILY MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="4">
        <location>
            <begin position="1"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="46"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="121"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="157"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="193"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="268"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00058490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="37185" checksum="2CC065ACEBE5BF1A" modified="2009-05-26" version="1">MDARFGSVDECLGQIGVLARDQHGCRFLQRKFDDEGEDAVNKCYDEIIAEVVDLMMDPFGNYLVQKLLECCNDEQRTGILKAGDGVPELVSVALNTHGTRAVQKLVETLRTPEHIRLATEALKPGVVTLIKDLNGNHVIQRCLQRLEAEDNQFVYDAAKACSVEIATHRHGCCVLQRCVDHAADSQRRALVNEIAAQALVLSQDPFGNYVVQYILDLGLPWANAEVMVRLGGAYAELSMQKFSSNVVEKCLKLAGQELEEHRNVVVREIMSSPLLDRLLMDPYGNYVVQSTLTVTKGSLHAELVERIRPHLPLIKNSPFGKRILRLLLESKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYT5</accession>
    <name>C1MYT5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_34797</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>diphosphate + H2O = 2 phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061095.1">
        <property type="nucleotide sequence ID" value="XM_003061049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYT5"/>
    <dbReference type="STRING" id="564608.C1MYT5"/>
    <dbReference type="GeneID" id="9686279"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34797"/>
    <dbReference type="eggNOG" id="KOG1626">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LYANEQK"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.80.10:FF:000007">
        <property type="entry name" value="Inorganic pyrophosphatase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="279" mass="31095" checksum="31A899ADE9B37119" modified="2009-05-26" version="1">MAIVRAAAPKPAAARQFARAPSALVAIAPNRHRAFRASVAAKAAYGKDEKGDYPSLDYRIFFKDGEKAISPWHDVPLYNADGTCNFICEIPKETKAKMEVATDEPLTPIKQDTKKGKLRDYPYNINWNYGMLPRTWEDPGHEHPEMKVMGDNDPVDVVEIGSAQREMGSVVPVKPVGVYAMIDDGELDWKVIAIAADDPKAKDVNDVADVEKHFPGELEKIRVWFRDYKTPDGKPQNAFGLNDECMDKAYTMAVIEETSGFYDKLKSGARENDKGLSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ84</accession>
    <name>C1MZ84_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60639</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061170.1">
        <property type="nucleotide sequence ID" value="XM_003061124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ84"/>
    <dbReference type="GeneID" id="9686353"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60639"/>
    <dbReference type="OMA" id="IMVEHES"/>
    <dbReference type="OrthoDB" id="10671920at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="585"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="77"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="226"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="367"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="461"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="594"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="610"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="680" mass="72755" checksum="54357CA6F74FB589" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZD1</accession>
    <name>C1MZD1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_19705</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060938.1">
        <property type="nucleotide sequence ID" value="XM_003060892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZD1"/>
    <dbReference type="STRING" id="564608.C1MZD1"/>
    <dbReference type="GeneID" id="9686632"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19705"/>
    <dbReference type="eggNOG" id="ENOG502RP77">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QPFKCGP"/>
    <dbReference type="OrthoDB" id="549173at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA/CobB_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002204">
        <property type="entry name" value="PRK01077.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="COBYRINATE A,C-DIAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873:SF1">
        <property type="entry name" value="COBYRINATE A,C-DIAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51274">
        <property type="entry name" value="GATASE_COBBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobQ/CobB/MinD/ParA nucleotide binding" evidence="7">
        <location>
            <begin position="4"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="CobB/CobQ-like glutamine amidotransferase" evidence="8">
        <location>
            <begin position="273"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="427" mass="43619" checksum="D55EA6A0C04272D7" modified="2009-05-26" version="1" fragment="single">MKVIVFAGTQAGVGKTTVAVGVMAALRQRGLRVQGFKVGPDLTDPLLHEAATGRPSYNLDGWMLSKEYNLGRVRRASIDADVAIVEGAEGLFDGVEGDERGSTGEIAKWLGAPVILVLDCASLRPRSAAAVLKGCLAFDDEVVVAGVVLNNTKNEAHAKIIRDAITAADLGVEVYGAVRTLESADGATNFLTTGRGGVSGASSVDRRRQLAIVANKALMAGGGTSLGQSQVVAGGNEDGGAIGHALGHLRGVGGNAASHLIPRTFSGGGGGVRIGVARDAAFCHYYRENLALLEAAGAELVAFSPLAGDSLPTGCKGILFGGGYPEQHANALASNRPLRMAITAFAAGGGVIYGECGGLVFLSQSLTPLEGSTPRPMCGLAPFSTRGVATEHSGYATVTIRQGCPLFPAGAKVRGQVCRNSEIASEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZI2</accession>
    <name>C1MZI2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynein light chain Tctex2b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_19963</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dynein light chain Tctex-type family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060958.1">
        <property type="nucleotide sequence ID" value="XM_003060912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZI2"/>
    <dbReference type="STRING" id="564608.C1MZI2"/>
    <dbReference type="GeneID" id="9686397"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19963"/>
    <dbReference type="eggNOG" id="KOG4108">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YVIRPNF"/>
    <dbReference type="OrthoDB" id="10260741at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21459">
        <property type="entry name" value="DLC-like_TCTEX1D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.40:FF:000003">
        <property type="entry name" value="tctex1 domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF7">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="122" mass="13800" checksum="DE363C8EE78EDC28" modified="2009-05-26" version="1">MHVDRSRCPALASPLRPRFKPGAVKAIIAECLKDKLAGKPYDPDECSMWAREISDEIKQRVKKLGYERYKIVCQVVVGEQKGEGVRMGARCFWDPKTDNYAEEVFTSESIFACGAAFGIYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZI6</accession>
    <name>C1MZI6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_44647</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061226.1">
        <property type="nucleotide sequence ID" value="XM_003061180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZI6"/>
    <dbReference type="STRING" id="564608.C1MZI6"/>
    <dbReference type="MEROPS" id="M24.009"/>
    <dbReference type="GeneID" id="9686399"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44647"/>
    <dbReference type="eggNOG" id="KOG2413">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EPGMILS"/>
    <dbReference type="OrthoDB" id="9995434at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.350.10:FF:000003">
        <property type="entry name" value="Xaa-pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000007">
        <property type="entry name" value="Xaa-Pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="6">
        <location>
            <begin position="277"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24 C-terminal" evidence="8">
        <location>
            <begin position="504"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="573" mass="62381" checksum="882731E9D88D7F50" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N025</accession>
    <name>C1N025_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_60944</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="function">
        <text evidence="2">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061052.1">
        <property type="nucleotide sequence ID" value="XM_003061006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N025"/>
    <dbReference type="STRING" id="564608.C1N025"/>
    <dbReference type="MEROPS" id="T01.A10"/>
    <dbReference type="GeneID" id="9686762"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60944"/>
    <dbReference type="eggNOG" id="KOG0175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NLGMAMQ"/>
    <dbReference type="OrthoDB" id="37597at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03761">
        <property type="entry name" value="proteasome_beta_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000034">
        <property type="entry name" value="Proteasome subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF3">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="7 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH54702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="286" mass="31299" checksum="805C32D03A1A73D0" modified="2009-05-26" version="1">MKLDFSVLDAPTRKIDAEIAECAAEINSDVHAQNFKLPMVENYDSFQREVVDYVKPNHGTTTLGFIFEHGVVIAVDSRASQGPYISSQTVKKVIEINPYLLGTMAGGAADCQFWQRNLGIQCRLHELENGKRISVSGASKLLSNTLYGYRGQGLSMGTMVAGWDLNGPGLYYVDSDGTRLKGKRFSVGSGSLFAYGVLDQGYRWDLSVEDACELGRRAIYHATFRDAFSGGTVSVYHVGPDGWTKMSGTDVGELHYEYYPADPIATEAEAEGGGEEPESMETSEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1N059</accession>
    <name>C1N059_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial</fullName>
            <ecNumber evidence="17">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MICPUCDRAFT_48178</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 17">Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="17">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="17">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="17">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of complex II composed of eight subunits in plants: four classical SDH subunits SDH1, SDH2, SDH3 and SDH4 (a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.), as well as four subunits unknown in mitochondria from bacteria and heterotrophic eukaryotes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 17">Mitochondrion inner membrane</location>
            <topology evidence="2 17">Peripheral membrane protein</topology>
            <orientation evidence="2 17">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="17"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061071.1">
        <property type="nucleotide sequence ID" value="XM_003061025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N059"/>
    <dbReference type="STRING" id="564608.C1N059"/>
    <dbReference type="GeneID" id="9686777"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48178"/>
    <dbReference type="eggNOG" id="KOG3049">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DGQYFGP"/>
    <dbReference type="OrthoDB" id="1696654at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045273">
        <property type="term" value="C:respiratory chain complex II (succinate dehydrogenase)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000007">
        <property type="entry name" value="Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000001">
        <property type="entry name" value="Succinate dehydrogenase iron-sulfur subunit SdhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050573">
        <property type="entry name" value="SDH/FRD_Iron-Sulfur"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004616">
        <property type="entry name" value="PRK05950.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921:SF29">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13534">
        <property type="entry name" value="Fer4_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="15 17" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7 17" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 17" id="KW-0408">Iron</keyword>
    <keyword evidence="14 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="18">
        <location>
            <begin position="61"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="19">
        <location>
            <begin position="197"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEH54721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="295" mass="32261" checksum="3936ADC997919643" modified="2009-05-26" version="1">MLAAFAKRAAGIASRASASSLASARSSAQFDVARVVTTSAPAAAAAEAAASSASSKPSNLQEFQIYRWDPETGGKPRYQTYKVDTNACGPMMLDVLFKIKDEQDNSLSFRRSCREGICGSCAMNIDGVNTLACLCKVDKSSDAPLKIAPLPHMFVVRDLVVDMANFYAQYKSIEPYLQTADGSEVLKGTEYHQSKEDRAKLDGLYECILCACCSTSCPSYWWNSDQYLGPAVLMQAYRWIIDSRDGKTEERLDKVNDAMKLFRCHTIMNCSKVCPKSLNPAHAIAKVKAMVTAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N080</accession>
    <name>C1N080_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_35156</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH55000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061350.1">
        <property type="nucleotide sequence ID" value="XM_003061304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N080"/>
    <dbReference type="GeneID" id="9686789"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35156"/>
    <dbReference type="eggNOG" id="KOG2417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IEIGVHW"/>
    <dbReference type="OrthoDB" id="264392at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010427">
        <property type="term" value="F:abscisic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025969">
        <property type="entry name" value="ABA_GPCR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022535">
        <property type="entry name" value="Golgi_pH-regulator_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015672">
        <property type="entry name" value="GPHR/GTG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 89-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948:SF0">
        <property type="entry name" value="GOLGI PH REGULATOR A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12430">
        <property type="entry name" value="ABA_GPCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12537">
        <property type="entry name" value="GPHR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Golgi pH regulator conserved" evidence="7">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Abscisic acid G-protein coupled receptor-like" evidence="6">
        <location>
            <begin position="157"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH55000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="386" mass="41440" checksum="B88A8E7FEE335A59" modified="2009-05-26" version="1">MGLFTMAQAVSRMGVIGVTMLAALSGFGAVHFPYTCLSFFARNVGEGELRAMQRRLLQATETVVSRKKKRALLLVELEDVRRGGREVGVDNGGDNPKPGMFRRFTNIGASFGASGRAKTIELQLDALDAEITALDHVTRSLFTETHEVRNARERAAESRTSWGALKNIMGWITSFACLWRVLVGTAHLLFKSGGAARTDPITTALSYAIVHRAGKGDAWDVRTLSQYLSLALIGFLVACSMRNFVWGMDRLFFAVGGGGGTSAMLVLFVTEIQGLYFLSSVLLIRDNLPERYRALITEALGADVKFVFYQSFYELIFLAAAALSIIILYAHRLHTMSVSSSTAGAGLGGGGGGDLSNAKRPGRGSAVPLAGVLCGVGVEDEKLAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0A2</accession>
    <name>C1N0A2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_50944</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061597.1">
        <property type="nucleotide sequence ID" value="XM_003061551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0A2"/>
    <dbReference type="GeneID" id="9686800"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50944"/>
    <dbReference type="OMA" id="FAIKCER"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF109">
        <property type="entry name" value="RIBOSOMAL LYSINE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="318" mass="34550" checksum="26ABF02218236191" modified="2009-05-26" version="1">MQIDFSADGFDFATSVGYERAVGDGEPIVLCGVPLVVEQTRDVDDDGGTGNVLWAGGVQLARELERGVARDELKWRLLLAEMDPRDGRRKEEDHLRSAPRAIELGAGCAGLPGVVLALRFGMRVTLTEHPLMIPTLTRNLESIKAQVNALAGAGSIEEDAVNAVNAIEIRALDWGDDDALAELAGGPGYQARSIHWSPYDPVGVLVVWADAGYRGDNALLLRAAIACVSPCGGIVLACEALRSETVTRTFRRRFGECGLFVVEILGEGGDSSETWTFTMRWQRKAEGIKAREAMASKRYVSKRVMRDEDEGSWGWGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0N5</accession>
    <name>C1N0N5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_62883</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061418.1">
        <property type="nucleotide sequence ID" value="XM_003061372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0N5"/>
    <dbReference type="STRING" id="564608.C1N0N5"/>
    <dbReference type="GeneID" id="9687113"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62883"/>
    <dbReference type="eggNOG" id="KOG0619">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="171"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="182"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="835" mass="88923" checksum="DE7D643EA64D0617" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1C5</accession>
    <name>C1N1C5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_11175</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061542.1">
        <property type="nucleotide sequence ID" value="XM_003061496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1C5"/>
    <dbReference type="STRING" id="564608.C1N1C5"/>
    <dbReference type="GeneID" id="9687229"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11175"/>
    <dbReference type="eggNOG" id="KOG1153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PEMWAKG"/>
    <dbReference type="OrthoDB" id="640735at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="6">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="222" mass="22379" checksum="805D54F0990D0D8E" modified="2009-05-26" version="1" fragment="single">GRGVHVYSLDTGVGVTHEDFTPHGRVESGWNFVGCDGKVFDASGHGTHVAATAVGATSGIAKCASLTPVQILDGEGRGSSSDVLSALDWVLEREIPPGHRKVVSMSVGGPRSEAVNAAVRDLTSLGVVVVAAAGNEREDARGVSPASEPTALTVGSTACRVAKTDGARCAGDAMSPFSNYGPVVDVFAPGSDVRSAWKTSDASYRVVSGTSMAAPLVAGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1F2</accession>
    <name>C1N1F2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PSII 6.1 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PSBW2</name>
        <name evidence="10" type="ORF">MICPUCDRAFT_51380</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the psbW family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061552.1">
        <property type="nucleotide sequence ID" value="XM_003061506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1F2"/>
    <dbReference type="STRING" id="564608.C1N1F2"/>
    <dbReference type="GeneID" id="9687246"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51380"/>
    <dbReference type="eggNOG" id="ENOG502SDRE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VMARECK"/>
    <dbReference type="OrthoDB" id="2017665at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042549">
        <property type="term" value="P:photosystem II stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009806">
        <property type="entry name" value="PSII_PsbW_class2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34552">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER W PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34552:SF1">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER W PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07123">
        <property type="entry name" value="PsbW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="119" mass="12195" checksum="0D8DE7FB4BE4A628" modified="2009-05-26" version="1">MACMSLSMSKALVAKPLARKVQARKAVVSKATVAKAQAPTKAVLSAAVVSLAAQALPALAVVDERLNGDGTGLILGLNDELLGFVLLTIPTLIFSQFYAAQKDEGIEAGGKNDDSGLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1S4</accession>
    <name>C1N1S4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_2195</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062170.1">
        <property type="nucleotide sequence ID" value="XM_003062124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1S4"/>
    <dbReference type="STRING" id="564608.C1N1S4"/>
    <dbReference type="GeneID" id="9687609"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2195"/>
    <dbReference type="eggNOG" id="KOG3628">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DEPGHTD"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22754:SF32">
        <property type="entry name" value="DISCO-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22754">
        <property type="entry name" value="DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="468" mass="49503" checksum="66E834DB016A49F3" modified="2009-05-26" version="1" fragment="single">PSPNPGDVAFVQYTSGSTSAPKGVVITHANVTHNCASIRRNFRVTAADVEVTWLPQYHDMGLVGAYLVPLTIPAAECDSNTPPPRTTCVSVSPVAFMRDPLVWARVASRYRATMTQAPDFAYRLCAARFNALPIHAREALGLDLSSLRHCLNAAERIDPRTSAVFAAAFEACGYSPGAMFHGYGLAESVVYVCDGPSRSISICGSSLERDKRAVVVVATGIDGRASSVVDVRRVASVGAPRGDVEVCVVHAARRARCADGEVGEIWVRSASIASGFWRRDGGDADDDGAFGATLADDVDGKRGGAFLRTGDEGFARDGELFVTGRSKDLIVVGGRNFAPEDIERTIRDADASEGWGDGTGASRARGALRPGSIAAFSIERDGSTTDESIGVIAETRDDAISASLAGVVVDGVRAVISQTHGVSVRREDVLLLRARTAPRTTSGKLRRRACAEAFRDGTLSVVDAMKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1T7</accession>
    <name>C1N1T7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51728</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062176.1">
        <property type="nucleotide sequence ID" value="XM_003062130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1T7"/>
    <dbReference type="GeneID" id="9687410"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51728"/>
    <dbReference type="OrthoDB" id="2012651at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="118" mass="12539" checksum="2ED4B7815306FA42" modified="2009-05-26" version="1">MCPIKPGAAVPTKPGVYWRDTSAWVRYADASATKIRLAEAQASLAKKEAPGSPRGPLDRAPSPAPSPSASSSPWLCETIVDLGDIGPSWLGGGSYRVDLARREQISPRGFVRPLLIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2F4</accession>
    <name>C1N2F4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_51508</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062078.1">
        <property type="nucleotide sequence ID" value="XM_003062032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2F4"/>
    <dbReference type="STRING" id="564608.C1N2F4"/>
    <dbReference type="GeneID" id="9687304"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51508"/>
    <dbReference type="eggNOG" id="KOG2831">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NPARWVV"/>
    <dbReference type="OrthoDB" id="564078at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13593">
        <property type="entry name" value="PBP2_HisGL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP-PRT_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403:SF10">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE ATP-PRTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP phosphoribosyltransferase catalytic" evidence="14">
        <location>
            <begin position="149"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine biosynthesis HisG C-terminal" evidence="15">
        <location>
            <begin position="317"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH53790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="391" mass="42468" checksum="6158BD79ECD19FEF" modified="2009-05-26" version="1">MSILVKVLSYTCTQPLSSLGYFLKKCTTSDRHSTRSDLNARSRARRSTKIRAAINPPYDLGIESAAPDESSSDVWSPAVDPLGTDFSSNAVPAAMTGKDKNCVRFGFPKGSLQKSTEELFARAGLPVKVKDRNYFPTVDDDGLSLVLFRSQEIPRYVADNVLDAGICGRDWIVENGSDVIEVAELKYSKATSNPARWVVAVPEDSPVRTAEDLEGTMIASELVNTTQRFFLDRDIHGVKVEYSWGATEVKASLPGVGAIVDITETGSSLRANKLREVATILESTTRLIANKDAWEDPIKRARIEDLALLLQGAIDGKKKVGLKMNLPTASVPELSAQLPSEKSPTVSPLLDADYCAVEVVVDEGTAKDLIPVVRRMGATGIVTYPINLSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N360</accession>
    <name>C1N360_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_52048</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062323.1">
        <property type="nucleotide sequence ID" value="XM_003062277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N360"/>
    <dbReference type="GeneID" id="9687993"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52048"/>
    <dbReference type="eggNOG" id="ENOG502S2DJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FMETGGM"/>
    <dbReference type="OrthoDB" id="1716650at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003832">
        <property type="entry name" value="DUF212"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31446">
        <property type="entry name" value="ACID PHOSPHATASE/VANADIUM-DEPENDENT HALOPEROXIDASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31446:SF29">
        <property type="entry name" value="ACID PHOSPHATASE_VANADIUM-DEPENDENT HALOPEROXIDASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02681">
        <property type="entry name" value="DUF212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="151" mass="15861" checksum="004A4DFE8F8099AB" modified="2009-05-26" version="1">MSPLGRGMPALVSSPALMAALLAFTYTTGKLDWTRVVGSGGMPSSHTSLVVGLATAVGLKESLDSSLFALCLVFSLVVMYDATGVRLHAGRQAEVLNEMIMNLPANHPVADARPLRDSLGHTPVQVGVGAVVGLLVGYLHYSSWVTQWGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3B9</accession>
    <name>C1N3B9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52114</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062352.1">
        <property type="nucleotide sequence ID" value="XM_003062306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3B9"/>
    <dbReference type="GeneID" id="9688023"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52114"/>
    <dbReference type="eggNOG" id="ENOG502S3IU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="185493at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="309" mass="32827" checksum="BAC88E52113C7A8C" modified="2009-05-26" version="1">MPACAALRGLVSARVVLHRARLALGAPVASSSSSSSSSSSSRRRGATASRGGRPRVPADRRAASSSSSSGDLEPRLPTGTRDRERAMGKIVSETAAHSRYLTVFDRVVEFDRRASYTSSDADPPSAVSTRVSYDVVGHPRNDFKFAVVFPFHSADATVTIVSEYCQGTNGRCVSLPTGGFDPTRHATLRDAAVAELAEEARLDGERVVECLVKGGDIGEANVESGGHPGFLESKWCANRFKPFLAVDATALSAADAATAHARDAEEFSMTTERVSVERLRELMRGGDMMVPSIVTANLALEKLAKDGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3E3</accession>
    <name>C1N3E3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_52141</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062364.1">
        <property type="nucleotide sequence ID" value="XM_003062318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3E3"/>
    <dbReference type="GeneID" id="9687804"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52141"/>
    <dbReference type="OMA" id="WAHLECA"/>
    <dbReference type="OrthoDB" id="7459479at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="41"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="260"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="275"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="459" mass="49567" checksum="49720AF2CF233CD4" modified="2009-05-26" version="1">MTTAAAEGRESPSRAPATCRHWLRARACLYGDSCKFAHPPDDAARSSVDDVESCRRPNGDGDGSTRRRRRRSRVRKRGKCGFMRRFLLDTYGVETLQSGVVVDVGGGRGELSFELENLNDVRCVVVDPQPLKVSRLEAKLRGGWYHRTAPLQRYNTRDAEGTARDGDEGGDDDRTGAGAGAAARRPAHWRLLWSPSLWSGDVGPTRTSVYRAWAAARTVRFFESGSGKETRAAAAAGGGGGAHDASSALVSRALKRLDDADVDVETARPRRPNDDTDAAADDDERCECGGRDDPSTTPEGVRPRDEVLKERRSPRERGRMGTSHDDAAAACDAFPPDAACDAFPPDAATVAAALASCSILVGMHPDQATEWIVDYALEHRKPFAVVPCCVCPTAFPRRRTSAGGAVITHDDFVAYLTRKGEDGEIASARLGFEGKDVVVYSTYGRRGGREDSARSQRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4R1</accession>
    <name>C1N4R1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52651</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062835.1">
        <property type="nucleotide sequence ID" value="XM_003062789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4R1"/>
    <dbReference type="GeneID" id="9688482"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52651"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="1">
        <location>
            <begin position="26"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="134" mass="14546" checksum="227D0AED7C0A09A4" modified="2009-05-26" version="1">MSTNSDNFDEDFAFTRAHVGESLNLACAVDGSRVSMKALELAFSLMRQKERGDTLTLVHVPDRTSRAPASASPAHIRSECELKCADARIDAKFVLAEPEKGGSVITAIADAAERVRSISHWFPYDRVGVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4Z3</accession>
    <name>C1N4Z3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52732</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062878.1">
        <property type="nucleotide sequence ID" value="XM_003062832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4Z3"/>
    <dbReference type="STRING" id="564608.C1N4Z3"/>
    <dbReference type="GeneID" id="9688521"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52732"/>
    <dbReference type="eggNOG" id="ENOG502RI4W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CKVSQLR"/>
    <dbReference type="OrthoDB" id="552188at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460:SF38">
        <property type="entry name" value="KINETOPLAST-ASSOCIATED PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="715"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="946" mass="97967" checksum="8A8E253A62863EA0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N515</accession>
    <name>C1N515_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66907</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063090.1">
        <property type="nucleotide sequence ID" value="XM_003063044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N515"/>
    <dbReference type="GeneID" id="9688331"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66907"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="219" mass="22260" checksum="1FC4CAA0652C14B9" modified="2009-05-26" version="1">MTRIFRRVGGFFFSAGGDVARGIDTARRVARAASVPNPPPPLASSRTRHGIARVRRRARRAPRSQPRAPPARRARVATVAASDATAPRRRRREAPADAVALSRASATTTTTTTTTTTLVAAGANLLFAGAALADDGGGGVNPLAFLAIVVPLAAFAFVKGSEGGGGGGGGGGGGGGGDDGGARERSQKSVDSENYQKNLTIAGGERTRKGRKPPKPKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N536</accession>
    <name>C1N536_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_52786</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062904.1">
        <property type="nucleotide sequence ID" value="XM_003062858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N536"/>
    <dbReference type="GeneID" id="9688538"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52786"/>
    <dbReference type="OMA" id="HGYWSPH"/>
    <dbReference type="OrthoDB" id="438715at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039210">
        <property type="entry name" value="OGFOD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14650:SF1">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14650">
        <property type="entry name" value="PROLYL HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="5">
        <location>
            <begin position="92"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="321" mass="33805" checksum="4AAD87673FA5CF70" modified="2009-05-26" version="1">MRGGGDVLRVGTAAWSAARDAWRDRAAASARALIASRTSAAKSPSTISTRFEHLATGSHPTPTRTTRRTRDGRDVSSVDALPPWPPGASPRPGRSRRHVIDGAFDARDVARLERVAATALDPLRDRARGDACVTVGRASESLLGEDAHVVMTRVLREMRVAAEDALRGDEGGKEDVALHPVGGLLTHIRAATTGGDGDDAATAAGGGREEHGYWSPHVDKANVPEYDISAVLYLSSGAGGGSDDDADAEDADFEGGEFAFLDGDDDDGVRRKRVVTPRRGRLVVFSSGEENVHAVGKVTRGGRSTLSLWLSGDARVAAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N585</accession>
    <name>C1N585_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mediator of RNA polymerase II transcription subunit 31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_21963</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Mediator complex subunit 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063127.1">
        <property type="nucleotide sequence ID" value="XM_003063081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N585"/>
    <dbReference type="STRING" id="564608.C1N585"/>
    <dbReference type="GeneID" id="9688364"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21963"/>
    <dbReference type="eggNOG" id="KOG4086">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QGILNQP"/>
    <dbReference type="OrthoDB" id="10257739at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1340">
        <property type="entry name" value="Mediator of RNA polymerase II, submodule Med31 (Soh1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038089">
        <property type="entry name" value="Med31_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008831">
        <property type="entry name" value="Mediator_Med31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13186">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05669">
        <property type="entry name" value="Med31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0010">Activator</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="146" mass="15989" checksum="8F64A1C2662D5696" modified="2009-05-26" version="1">MAPTAAETRAAEIATGLPNDKRFILELEFVMALANPRYVHHLAVNDILDDPAFVAYLDYLSYWTRPEYARFVQYPHALYFLEQLEDPAFRAAMRNPRACEHVFAAQYYHWQNARTDRANAKIAAEAAAAAAGGGGGGGGGREAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5K0</accession>
    <name>C1N5K0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52950</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063171.1">
        <property type="nucleotide sequence ID" value="XM_003063125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5K0"/>
    <dbReference type="GeneID" id="9688816"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52950"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="728" mass="78428" checksum="35653822B1C6EA19" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5P5</accession>
    <name>C1N5P5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_52989</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063194.1">
        <property type="nucleotide sequence ID" value="XM_003063148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5P5"/>
    <dbReference type="STRING" id="564608.C1N5P5"/>
    <dbReference type="GeneID" id="9688838"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52989"/>
    <dbReference type="eggNOG" id="KOG4419">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CTLNGDF"/>
    <dbReference type="OrthoDB" id="10252235at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="814"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="15"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="473"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="883"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="902" mass="93071" checksum="C199A3B97BD8826B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N620</accession>
    <name>C1N620_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53127</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063257.1">
        <property type="nucleotide sequence ID" value="XM_003063211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N620"/>
    <dbReference type="STRING" id="564608.C1N620"/>
    <dbReference type="GeneID" id="9688900"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53127"/>
    <dbReference type="OMA" id="FFCGYKS"/>
    <dbReference type="OrthoDB" id="10594112at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.340">
        <property type="entry name" value="Nucleoplasmin core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041232">
        <property type="entry name" value="NPL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17800">
        <property type="entry name" value="NPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoplasmin-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="443" mass="44917" checksum="67C814DA50EFF958" modified="2009-05-26" version="1">MPQFFGIEIPKGQSKKFAADEGDAIVVCQAALGLKPKQDERVTVFVKTADSPELAIGTLRMGSCDQFSLGTGLTFSSGETVTVRHTGSTSVFLTGRIEDDFDDDFPMSDSDGEGDDGKPSEPPAKAAKAKAKAAPAPAPAAAESESESESESESEDGDAPSDDSDESESDDAEDPKEKTKKLAAAAAAAKPADDASDSEEDDESEEEEGEDSEDDASDDSSSDEEDEGKPSAAKKPPASASKKPPTPAAESESESESESEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDKDAPAPTGGDSDSDSEEDDESDSEEDGSDDSDGSDSDSDDEKPGEKRKASGGGGRGGGTPKTAKVADGRSGGGGRGGGGGGGRGGFSPGGRGGRGGFSPGGRGGRGGFSPGGRGGRGGRGGGGRGFSPGGRGGGGRGRGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6C1</accession>
    <name>C1N6C1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_22242</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063312.1">
        <property type="nucleotide sequence ID" value="XM_003063266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6C1"/>
    <dbReference type="STRING" id="564608.C1N6C1"/>
    <dbReference type="GeneID" id="9688946"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22242"/>
    <dbReference type="eggNOG" id="KOG0446">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DGHYRNI"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF223">
        <property type="entry name" value="PROTEIN 1C, PUTATIVE, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="23"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="526"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="499"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH52448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="614" mass="66876" checksum="5956DDA157C8B009" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6U4</accession>
    <name>C1N6U4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Queuosine 5'-phosphate N-glycosylase/hydrolase</fullName>
            <ecNumber evidence="6">3.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 6">Queuosine-nucleotide N-glycosylase/hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_53443</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>queuosine 5'-phosphate + H2O = queuine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:75387"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:194371"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5 6">
            <dbReference type="Rhea" id="RHEA:75388"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the QNG1 protein family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="6"/>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063614.1">
        <property type="nucleotide sequence ID" value="XM_003063568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6U4"/>
    <dbReference type="STRING" id="564608.C1N6U4"/>
    <dbReference type="GeneID" id="9689233"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53443"/>
    <dbReference type="eggNOG" id="KOG2524">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FATEYNG"/>
    <dbReference type="OrthoDB" id="416777at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019438">
        <property type="entry name" value="Q_salvage"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314:SF0">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10343">
        <property type="entry name" value="Q_salvage"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="383" mass="42371" checksum="9B988A6686F04A03" modified="2009-05-26" version="1">MAACAAVRESTARVAAAATHVAIDDTVIAKLVDEMPPEVVATMLGPRDFDVDEIHFLDASDEDLTARYLLCVDAINFCFWPDHDGDGGASLLAWQRDFGCDDKQLAGDPDLLYWQNAFKGDAKPKDLSGDKQGLEYEHVAGGLKRALTRDDDALDVDKLKAMTGTRLRELLKWPRPLPLEEERARLLREVGTQLDVLWDGSAAKMIRAARQSAPALVDIVAKTFPGFRDVAVYARDGMQCFLYKRAQIFVGDVWGRFGGAGLGDFADSIKELTMFADYRVPVVLRNLGVLRYDENLSVKVDRAVGTIPAGSDEEVEIRACSVQAVERIRALLEKRLEVEHELQPVAGLGPGLTSVAIDWYLWGVGEKDRDEGPPHHRTITVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N708</accession>
    <name>C1N708_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Early light induced protein-like 6, chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CBR/ELIP1</name>
        <name evidence="1" type="ORF">MICPUCDRAFT_48963</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063824.1">
        <property type="nucleotide sequence ID" value="XM_003063778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N708"/>
    <dbReference type="STRING" id="564608.C1N708"/>
    <dbReference type="GeneID" id="9689265"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48963"/>
    <dbReference type="OMA" id="ARKEMIH"/>
    <dbReference type="OrthoDB" id="513190at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="17742" checksum="C4F33EA687513B10" modified="2009-05-26" version="1">MFALASSSASVSARATSPNRASSGARGAAVVAAAGVEPIPASEAMKLAESGKVAKRKGFVETMGFAGWAPEVINGRVAQIAFVAGAAAEAVTGETLPAQAHDHVFSLAFASSLIALASFMPNVQGEKYTSEPESKGAFGPFSPGKELLHGRLAMVGLAAWIAIESHTGVAFFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N727</accession>
    <name>C1N727_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_1244</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063659.1">
        <property type="nucleotide sequence ID" value="XM_003063613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N727"/>
    <dbReference type="STRING" id="564608.C1N727"/>
    <dbReference type="GeneID" id="9689100"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_1244"/>
    <dbReference type="eggNOG" id="KOG1000">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FTLHRAR"/>
    <dbReference type="OrthoDB" id="2801544at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18010">
        <property type="entry name" value="DEXHc_HARP_SMARCAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010003">
        <property type="entry name" value="HARP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766:SF3">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07443">
        <property type="entry name" value="HARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51467">
        <property type="entry name" value="HARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HARP" evidence="7">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="111"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="374"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="518" mass="56466" checksum="E5DF95A43D2C6856" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7C8</accession>
    <name>C1N7C8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65946</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063876.1">
        <property type="nucleotide sequence ID" value="XM_003063830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7C8"/>
    <dbReference type="STRING" id="564608.C1N7C8"/>
    <dbReference type="GeneID" id="9689155"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65946"/>
    <dbReference type="eggNOG" id="KOG1454">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SSPREIW"/>
    <dbReference type="OrthoDB" id="498673at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689:SF8">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="244" mass="25782" checksum="5FE5BC9299D5A91C" modified="2009-05-26" version="1">MGALAVALAAGEGGIDDVVLVAPAIVPKRRRKNTERQPARKRLWTRPLGVLIALASAVARVVVAALARALSPFLVLFLRKIVRNAAFWREGLASAVGSPMRRVMRDDRSWTDGYRRPSVVTGWDRGMARVVLSAATGGLDGVAATARDGARRVARAVSGEESGEEDAAEALARSGARVLIVHGDEDVIVPALPRAELVVVRGCGHMPHEECPDVFLDAVRAFLRKGERGGDGDDAGAGAGVEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8M8</accession>
    <name>C1N8M8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_66433</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-3' exonuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064110.1">
        <property type="nucleotide sequence ID" value="XM_003064064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8M8"/>
    <dbReference type="STRING" id="564608.C1N8M8"/>
    <dbReference type="GeneID" id="9689737"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66433"/>
    <dbReference type="eggNOG" id="KOG2044">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="496718at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="3">
        <location>
            <begin position="75"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="335" mass="36256" checksum="19DFFC1EBE0EF021" modified="2009-05-26" version="1">MAGMADPGGGGRWRAVASSSSASSTSASSASLSSTIIHLMNHRRSAVVARRPSDDDETRRRGRGSLATMRGVGSGFGKWMQKTYPECFETHGGLRGQGDGGGGRGGRGRGGRGTAGRGGGRPVDPQRTQLGTYDHVYVDVNNVLHVAAHHTKTEEAFFKKLFALLDRTMRLTRPQYTVTLALDGPAPIAKTITQRRRRIRLSSGEKVPLSEDAPRLLKIGLTPGSTLALRIDRALEYYAATRLLSRNHLPRGVLFEISGTRVPGEGEVKVLRSMKTREKNARFKGHSHLIVSEDSDALLLALTAEPANVFVLSSKVRSISHWSPYDPVRVVNAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8W9</accession>
    <name>C1N8W9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43431</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064348.1">
        <property type="nucleotide sequence ID" value="XM_003064302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8W9"/>
    <dbReference type="GeneID" id="9689789"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43431"/>
    <dbReference type="OMA" id="RKDAKQW"/>
    <dbReference type="OrthoDB" id="194772at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136:SF1">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rubredoxin-like" evidence="2">
        <location>
            <begin position="56"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="144" mass="15179" checksum="4B3B5B214E4A7774" modified="2009-05-26" version="1">MSFAVSAPVTSARPAFLGGASALRASSKSAARTPAGRTSTTTMAFFGMGAAKQPPGVAMVCRDCGYVYRGTDFNDLPKDYKCPPCGSGKNAFRPEKKMDYKKDGFNAPGIRAAKRENKKAFEAKRAAARKAAEGGGKKKGLFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9B3</accession>
    <name>C1N9B3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54434</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064424.1">
        <property type="nucleotide sequence ID" value="XM_003064378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9B3"/>
    <dbReference type="GeneID" id="9690029"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54434"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="297" mass="31387" checksum="0191A287548F6438" modified="2009-05-26" version="1">MGKANSKHRPGGPCCGEDLADLARVDASADDVDENEDERGGGGGGRGGRWTVLSESEAAGAAAATAAIARASGDAAPPPPPPPPSSPPAPSPSPRPPPPTDREEEEKEEEEAKVVVASPSPSPPPSPRRADADPVDVFLAIDETGVVRATLRVKHRAVCRLATRPASSAATRPPAPAATRRDASRFFVDDSDLYPGGMHQPVDPSIPMAIKTHQIDTLEASARARDDERLYPCGMHQPVEPHPPATTAAGQVRRVLYTGSHTTPFAWWTPILKDFARRVSPPTPPFQYPPSTPFNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9W8</accession>
    <name>C1N9W8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54670</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064806.1">
        <property type="nucleotide sequence ID" value="XM_003064760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9W8"/>
    <dbReference type="GeneID" id="9690129"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54670"/>
    <dbReference type="OrthoDB" id="10406639at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="242" mass="25112" checksum="C4EF53002D594C4E" modified="2009-05-26" version="1">MERPSQDPLKLLGLPGAPVDVDGKVTWENHPAMRSNDVAMRAKIMSMRCDPSRFPAGDAARDKLRAVAEDAHAAVLAAAATLQDPDARKAALTLAVQRRVDEMRRVDQGGEEEGGETHGGGALLPEGGYVTATGVHFAAGAAIARVADAARASETGHGPMMNPALAVGRAMAAANKAGDERKSEGKSERERGGEGEGEGEGDEARERARAGAGGGGGGGEREGKVDLSALRDKLKKKRPSFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Y4</accession>
    <name>C1N9Y4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49303</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064813.1">
        <property type="nucleotide sequence ID" value="XM_003064767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Y4"/>
    <dbReference type="STRING" id="564608.C1N9Y4"/>
    <dbReference type="GeneID" id="9690254"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49303"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037386">
        <property type="entry name" value="CCDC40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275:SF8">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="215" mass="24192" checksum="20A13FBD4CC0E43A" modified="2009-05-26" version="1">MRKEINRMEHKHGELKRRQEKLIQEMEKAIYKRQLIQTKALSAAARNEGGSSSSSASLKGRAAKKDEMTKAGLKKACAALKKSIRETESGGAEADARIERLEDDGVCAATEADRFSAEIERLRVEESTLRAERDAKAREREVLQLEAAKSARMRKRFEDVVEGRHRVLASDEDVVADLEKARRRREKLLSAVEDACEAAPHLWPSLERALTLLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Z3</accession>
    <name>C1N9Z3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54697</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064698.1">
        <property type="nucleotide sequence ID" value="XM_003064652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Z3"/>
    <dbReference type="STRING" id="564608.C1N9Z3"/>
    <dbReference type="GeneID" id="9690262"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54697"/>
    <dbReference type="eggNOG" id="KOG2595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="206700at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045913">
        <property type="entry name" value="TBC20/Gyp8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913:SF7">
        <property type="entry name" value="RE60063P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 20/GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="568" mass="63002" checksum="89F80986305C6E4C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA02</accession>
    <name>C1NA02_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_67796</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064824.1">
        <property type="nucleotide sequence ID" value="XM_003064778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA02"/>
    <dbReference type="GeneID" id="9690145"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67796"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="311" mass="34190" checksum="EB00A7A4F733D1EE" modified="2009-05-26" version="1">MAVARAWDAETRREKRIRALTRRHRWKAERRAMRAIVDAWRWEVLTSKSTKKEAKDDDGIRGGGGVPPAAVEEARVSLRVCVIQPPPPPPMPSASMRESRETQTPTAARAKIFHREEETTTAPATRTFLVKKTKKKRPAIHSAVKRWHGAAYAPPTRPKPKPASTLVTPRRIRRETGETALVSPPKTAAWDASIYKPPETATPPPWMPLGDSPAMASVAAAAKAALKSARRREPLPATPSDDTFAGLDLGDPTDDDEEPPAPKRVPGRGGGAPKVRAKYWVSSRGGSRVDARAARRSDAHYEHYDVARNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRD1</accession>
    <name>C1KRD1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 25">Photosystem I P700 chlorophyll a apoprotein A1</fullName>
            <ecNumber evidence="4 25">1.97.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="25">PSI-A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="23 25">PsaA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="primary">psaA</name>
        <name evidence="27" type="ORF">MicpuC_chl33</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="27"/>
    <reference evidence="28" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="28">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 25">PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24 25">
            <text>reduced [plastocyanin] + hnu + oxidized [2Fe-2S]-[ferredoxin] = oxidized [plastocyanin] + reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:30407"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10039"/>
            <dbReference type="Rhea" id="RHEA-COMP:10040"/>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <dbReference type="ChEBI" id="CHEBI:30212"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
            <dbReference type="EC" id="1.97.1.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="22 25">The PsaA/B heterodimer binds the P700 chlorophyll special pair and subsequent electron acceptors. PSI consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The eukaryotic PSI reaction center is composed of at least 11 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 25">Plastid</location>
            <location evidence="2 25">Chloroplast thylakoid membrane</location>
            <topology evidence="2 25">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 25">Belongs to the PsaA/PsaB family.</text>
    </comment>
    <dbReference type="EC" id="1.97.1.12" evidence="4 25"/>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRD1"/>
    <dbReference type="STRING" id="564608.C1KRD1"/>
    <dbReference type="OMA" id="TWAFFHA"/>
    <dbReference type="OrthoDB" id="15at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1130.10:FF:000001">
        <property type="entry name" value="Photosystem I P700 chlorophyll a apoprotein A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1130.10">
        <property type="entry name" value="Photosystem I PsaA/PsaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00458">
        <property type="entry name" value="PSI_PsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006243">
        <property type="entry name" value="PSI_PsaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001280">
        <property type="entry name" value="PSI_PsaA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020586">
        <property type="entry name" value="PSI_PsaA/B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036408">
        <property type="entry name" value="PSI_PsaA/B_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01335">
        <property type="entry name" value="psaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30128">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN, OMPA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30128:SF19">
        <property type="entry name" value="PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00223">
        <property type="entry name" value="PsaA_PsaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002905">
        <property type="entry name" value="PSI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00257">
        <property type="entry name" value="PHOTSYSPSAAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81558">
        <property type="entry name" value="Photosystem I subunits PsaA/PsaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00419">
        <property type="entry name" value="PHOTOSYSTEM_I_PSAAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 25" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 25" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="27" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="16 25" id="KW-0157">Chromophore</keyword>
    <keyword evidence="14 25" id="KW-0249">Electron transport</keyword>
    <keyword evidence="18 25" id="KW-0408">Iron</keyword>
    <keyword evidence="19 25" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13 25" id="KW-0460">Magnesium</keyword>
    <keyword evidence="21 25 26" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 25" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17 25" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 25" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="12 25" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="27" id="KW-0934">Plastid</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20 25" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="10 25 26" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15 25 26" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 25" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="533"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="592"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="665"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="728"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="575"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="584"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="25">
        <location>
            <position position="676"/>
        </location>
        <ligand>
            <name>chlorophyll a'</name>
            <dbReference type="ChEBI" id="CHEBI:189419"/>
            <label>A1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="25">
        <location>
            <position position="684"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>A3</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="692"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>A3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="693"/>
        </location>
        <ligand>
            <name>phylloquinone</name>
            <dbReference type="ChEBI" id="CHEBI:18067"/>
            <label>A</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00026002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00031004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00048912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="ACO50763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="751" mass="83260" checksum="B40E88A4F058E680" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGR4</accession>
    <name>C1MGR4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_13509</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055364.1">
        <property type="nucleotide sequence ID" value="XM_003055318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGR4"/>
    <dbReference type="STRING" id="564608.C1MGR4"/>
    <dbReference type="GeneID" id="9680231"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13509"/>
    <dbReference type="eggNOG" id="KOG4254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GPSFYCG"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016116">
        <property type="term" value="P:carotenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045892">
        <property type="entry name" value="CrtISO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313:SF3">
        <property type="entry name" value="PROLYCOPENE ISOMERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="62"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="571" mass="60663" checksum="4EA4DC04CACB82AA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHI2</accession>
    <name>C1MHI2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50207</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054957.1">
        <property type="nucleotide sequence ID" value="XM_003054911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHI2"/>
    <dbReference type="GeneID" id="9680686"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50207"/>
    <dbReference type="eggNOG" id="KOG0001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YAGKQMA"/>
    <dbReference type="OrthoDB" id="472at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01806">
        <property type="entry name" value="Ubl_NEDD8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000023">
        <property type="entry name" value="NEDD8 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038738">
        <property type="entry name" value="Nedd8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="77" mass="8655" checksum="0A972D5887103346" modified="2009-05-26" version="1">MIKVKTLTGKEIEIDIEPTDSIERIKERVEEKEGIPPVQQRLIFGGKQMNDDKIAKDFNIEGGSVLHLVLALRGGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHN7</accession>
    <name>C1MHN7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_46251</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tectonic family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055523.1">
        <property type="nucleotide sequence ID" value="XM_003055477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHN7"/>
    <dbReference type="STRING" id="564608.C1MHN7"/>
    <dbReference type="GeneID" id="9680901"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46251"/>
    <dbReference type="OMA" id="LNGAQIC"/>
    <dbReference type="OrthoDB" id="2104337at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040354">
        <property type="entry name" value="TCTN1-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011677">
        <property type="entry name" value="TCTN1-3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057724">
        <property type="entry name" value="TCTN1-3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14611:SF2">
        <property type="entry name" value="TECTONIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14611">
        <property type="entry name" value="TECTONIC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25752">
        <property type="entry name" value="DUF1619_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07773">
        <property type="entry name" value="TCTN_DUF1619"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002911936" evidence="6">
        <location>
            <begin position="35"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="745"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="Tectonic-1-3 N-terminal" evidence="8">
        <location>
            <begin position="60"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Tectonic-1-3" evidence="7">
        <location>
            <begin position="438"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="772" mass="80012" checksum="40E3259C3C3B4E65" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIB3</accession>
    <name>C1MIB3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Chloroplast envelope protein translocase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">TIC55-6</name>
        <name evidence="16" type="ORF">MICPUCDRAFT_50506</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055098.1">
        <property type="nucleotide sequence ID" value="XM_003055052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIB3"/>
    <dbReference type="STRING" id="564608.C1MIB3"/>
    <dbReference type="GeneID" id="9680335"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50506"/>
    <dbReference type="eggNOG" id="ENOG502QQ8U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KIDWRHE"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010277">
        <property type="term" value="F:chlorophyllide a oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.380.10">
        <property type="entry name" value="Naphthalene 1,2-dioxygenase Alpha Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050584">
        <property type="entry name" value="Cholesterol_7-desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013626">
        <property type="entry name" value="PaO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266:SF32">
        <property type="entry name" value="CHOLESTEROL 7-DESATURASE NVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266">
        <property type="entry name" value="IRON-SULFUR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08417">
        <property type="entry name" value="PaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="16" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="16" id="KW-0946">Virion</keyword>
    <feature type="domain" description="Rieske" evidence="15">
        <location>
            <begin position="101"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH60350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="662" mass="71732" checksum="D6BE365EC013F1D9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIM1</accession>
    <name>C1MIM1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_50620</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055155.1">
        <property type="nucleotide sequence ID" value="XM_003055109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIM1"/>
    <dbReference type="GeneID" id="9680708"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50620"/>
    <dbReference type="eggNOG" id="KOG2615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EVIPLWA"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="535"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="634"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="274"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="406"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="665" mass="69879" checksum="9EC81FE3123E3A4A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIS3</accession>
    <name>C1MIS3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_6513</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055182.1">
        <property type="nucleotide sequence ID" value="XM_003055136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIS3"/>
    <dbReference type="STRING" id="564608.C1MIS3"/>
    <dbReference type="ESTHER" id="9chlo-c1mis3">
        <property type="family name" value="Duf_1350"/>
    </dbReference>
    <dbReference type="GeneID" id="9680737"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6513"/>
    <dbReference type="eggNOG" id="ENOG502SRV8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3980at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010765">
        <property type="entry name" value="DUF1350"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34127">
        <property type="entry name" value="OS04G0405600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34127:SF1">
        <property type="entry name" value="OS04G0405600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07082">
        <property type="entry name" value="DUF1350"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="231" mass="24681" checksum="3CCAD81B6BA039FB" modified="2009-05-26" version="1" fragment="single">WEEIDGSYVRAPSGRAWGVVHFIGGAVLGSYPHIAYDAFLSRVSDDAGVVVVATPYDLGVDHGKISRECATKLNRAWAAFATREGYDLANTPVFAFGHSLGCKLHLVAACGDGEGDGDGESAAAKRAGHLFVAFNNATAADSVRLLEKFAKELRAASAAGLDFTPSPAETLERAKRGFESPRATLLSFEEDDLDQNDELMEVLRHRYAMTTVSGDAPVSAVRLRGTHLTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK15</accession>
    <name>C1MK15_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_64169</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PDCD4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056312.1">
        <property type="nucleotide sequence ID" value="XM_003056266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK15"/>
    <dbReference type="STRING" id="564608.C1MK15"/>
    <dbReference type="GeneID" id="9681914"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64169"/>
    <dbReference type="eggNOG" id="KOG0403">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="414546at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039778">
        <property type="entry name" value="PDCD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12626">
        <property type="entry name" value="PROGRAMMED CELL DEATH 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12626:SF0">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="MI" evidence="6">
        <location>
            <begin position="9"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="MI" evidence="6">
        <location>
            <begin position="189"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="466" mass="50338" checksum="A02DF7446884EF1B" modified="2009-05-26" version="1" fragment="single">MPGTMTELDFKRECESMVREYFTHGVMADVLTSVLDLLDRAETPTPLGHTRLLNPSTTRPAVVKRAVVASLDRGPREREMAARFLQALAVHEVIAPAHLEAGFDLILQDLDSLVIDVPRVPTELSHFISRAVVDGVVSRKFLDDSADAEGVDITSHQVAVTARGALRQPGGESHVRAVWGGPEGTTADAARREMRNLLEEYISSGDVAEASRRLAELGVPFYHHEFVRRALTHAIESFAVNSQRPRTITRLLGYLNATGLVSGTQFAKGFARVATSLTEITLDVPDARERFEELVGVAKDEGLLPAALSAWASLRDCGVRGSKELTGCDGLKPVGDNRSLRGHMLRLDSAPDLIQLAEIVGGSRSPVEVDTESNSTEIPAALHLSPANERGKCANERSTTASVLSPESMYIMDDGSHKNESVGIAPAIGKAIIDRCNGALSSASVPNGNQLNSGWSGFRVMRTKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK31</accession>
    <name>C1MK31_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55196</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055921.1">
        <property type="nucleotide sequence ID" value="XM_003055875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK31"/>
    <dbReference type="GeneID" id="9681460"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55196"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910503" evidence="2">
        <location>
            <begin position="24"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="162" mass="17278" checksum="9EF1BE1E0462C581" modified="2009-05-26" version="1">MARIAHLLLLALALSALSSPRLALGVDLSLAALHARAGCAEHTYPYAWSGTHPSHAHASGTAPAPHHSTPDPHHDGGEEAYVDAYDSPPTAPGIDIVTPHTPAAVCDTTQFTEQLPELLPSLPRASQCRRHRNSVATPSRTRSARTKTLRCPRAYATETRSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK43</accession>
    <name>C1MK43_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55205</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055927.1">
        <property type="nucleotide sequence ID" value="XM_003055881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK43"/>
    <dbReference type="GeneID" id="9681921"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55205"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="19478" checksum="6BA7DDB26DFC3C55" modified="2009-05-26" version="1">MSRGRMPRRPFVTATSPTSLHSCATARTTRSWVRTLLPPALPSLWLRMWWTALCVNVALPHSAWWRASFRSMRTLMAAGIEAELEANLVSHVSGGELPGLRERDHRVPGGRAFAPERVHGYRDLGGELADVWVRGVQVHVQMYGSIYTLYNVGCTRTPVHVYNVVTVQYVYCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK66</accession>
    <name>C1MK66_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_14140</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055945.1">
        <property type="nucleotide sequence ID" value="XM_003055899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK66"/>
    <dbReference type="STRING" id="564608.C1MK66"/>
    <dbReference type="GeneID" id="9681313"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14140"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="515324at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="5">
        <location>
            <begin position="94"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="224" mass="24386" checksum="53612B3909776E79" modified="2009-05-26" version="1" fragment="single">MNTIQRVLGHEIDPHKPLIEAGIDSLSMTELGQAIEIDIGVSLPTTVAFDYPTVSAIASFVSDKMGFSTTDTSACCTNAPPRGREFENTYRKSIDLAVVMGIGCRFAGKGKSDSDSLGKFWQLISSGGDAITTVPLDRWDVDTDTTAFGICRRRDPYTERYSRHGSFVSDIDHFDCLFFDVSNAEATAIDPQQRMILKVVVDAMYGAGMTKDLSRGSNTAVYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK77</accession>
    <name>C1MK77_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64253</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056335.1">
        <property type="nucleotide sequence ID" value="XM_003056289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK77"/>
    <dbReference type="GeneID" id="9681317"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64253"/>
    <dbReference type="eggNOG" id="KOG2977">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GWPEDYD"/>
    <dbReference type="OrthoDB" id="497480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22916">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22916:SF3">
        <property type="entry name" value="UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="1">
        <location>
            <begin position="133"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="1">
        <location>
            <begin position="220"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="529" mass="59363" checksum="39E70B98D3058B4D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKC0</accession>
    <name>C1MKC0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="10">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_24753</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="10"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056361.1">
        <property type="nucleotide sequence ID" value="XM_003056315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKC0"/>
    <dbReference type="STRING" id="564608.C1MKC0"/>
    <dbReference type="GeneID" id="9681484"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_24753"/>
    <dbReference type="eggNOG" id="KOG0376">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IHKKYAF"/>
    <dbReference type="OrthoDB" id="445564at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07417">
        <property type="entry name" value="MPP_PP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041753">
        <property type="entry name" value="PP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013235">
        <property type="entry name" value="PPP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051134">
        <property type="entry name" value="PPP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08321">
        <property type="entry name" value="PPP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033096">
        <property type="entry name" value="PPPtase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="11">
        <location>
            <begin position="290"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="8">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR033096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH59737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="483" mass="54250" checksum="FCB80A7D43A682ED" modified="2009-05-26" version="1">MEAPTPQSAQDTTIACNPIQLNALKTAANILFNERKYAKAVVAYSKALQVSPTSAVLLANRALAHLHLENYASAFDDSSLAIRLDPGYVKGYYRRGSSNFILGKFGSALKDFEKVVQLQPRNLEGKKKVRECELALRKQRFEYAIRVPESVLVKVSDSIELDTITVENTYDGPRLGENHTVTANFVKDMILQFKNCKAIHLRRYAYEILLQTNLHICSVPSLLGKHITVCGDIHGQFFDLCNIFELNGEPSEDNPYLFNGDFVDRGSFSVEVVLTLFAFMCLCPESLRLIRGNHETSAMNKLYGFDGEVRAKYNGKLADLFQEIFCCLPLGCVLGKKVFIVHGGLFSKDGVKVEDLKSIDRFHEPPDEGPFCEMLWSDPCCEPGRYPSKRGIGIAFGPDVTKKFIIENNLELVIRSHEVKDDGFEIEHDGSLITVFSAPNYCDQMENKGAFIRFESDMVPHITTFNAVNHPPVRPMQFAPHIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKY7</accession>
    <name>C1MKY7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55508</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056467.1">
        <property type="nucleotide sequence ID" value="XM_003056421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKY7"/>
    <dbReference type="GeneID" id="9681378"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55508"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="107" mass="11646" checksum="17CA81A06D46561A" modified="2009-05-26" version="1">MGAVTYYGNAQKIYVATDAAIGVGLGLVAGGAWKVHVALGNTQEGRNVPREELSAQDGRVLLRQRSSVLESQSCWLHTGICKKSGKIVHVRAPPKVTSPFRRRVRYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML08</accession>
    <name>C1ML08_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">B-type asparagine synthetase chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ASNB</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_25035</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056475.1">
        <property type="nucleotide sequence ID" value="XM_003056429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML08"/>
    <dbReference type="STRING" id="564608.C1ML08"/>
    <dbReference type="GeneID" id="9681548"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25035"/>
    <dbReference type="eggNOG" id="KOG0571">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HHEYLFT"/>
    <dbReference type="OrthoDB" id="409189at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050795">
        <property type="entry name" value="Asn_Synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006949">
        <property type="entry name" value="PRK09431.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772:SF2">
        <property type="entry name" value="ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="5">
        <location>
            <begin position="79"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="622" mass="69345" checksum="1B5DFF8BC4416B0B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML63</accession>
    <name>C1ML63_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55590</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056119.1">
        <property type="nucleotide sequence ID" value="XM_003056073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML63"/>
    <dbReference type="STRING" id="564608.C1ML63"/>
    <dbReference type="GeneID" id="9681762"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55590"/>
    <dbReference type="eggNOG" id="ENOG502T1WK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="608866at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052450">
        <property type="entry name" value="TRBD-Containing_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734:SF1">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1 TERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="140"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="257" mass="28945" checksum="CBC2F65C74665414" modified="2009-05-26" version="1">MSTPAEVNNANYDYSFENDEDPTVNCTITIRWDGNDMPLRVPQTTCTNTRIKDIISLKTCGRLLPNRMHLSYNGVEVGLHPPGTLISDLGVGVDSALLTLTILPEVSTSTHISRRVDMPAILPLHKITNSFKNVKRKRVRAQGNNERFTREEAEALVTGVSSYGIGNWVIILKQHFKNSARSSVDLKDKWRNMCAAAFRPHGFKFRVSYFTPDFLAKVRSVQAEAEQRSRLMAKSQELELRDKKNARLAKLAELTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML69</accession>
    <name>C1ML69_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM7</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">MCM7</name>
        <name evidence="14" type="ORF">MICPUCDRAFT_49470</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056122.1">
        <property type="nucleotide sequence ID" value="XM_003056076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML69"/>
    <dbReference type="STRING" id="564608.C1ML69"/>
    <dbReference type="GeneID" id="9681563"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49470"/>
    <dbReference type="eggNOG" id="KOG0482">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AQHVTYV"/>
    <dbReference type="OrthoDB" id="3207464at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17758">
        <property type="entry name" value="MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000826">
        <property type="entry name" value="Replicative DNA helicase Mcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008050">
        <property type="entry name" value="MCM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01663">
        <property type="entry name" value="MCMPROTEIN7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="331"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH59498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="723" mass="79931" checksum="29FBCE2DEBB743CA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLE6</accession>
    <name>C1MLE6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_55685</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056153.1">
        <property type="nucleotide sequence ID" value="XM_003056107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLE6"/>
    <dbReference type="STRING" id="564608.C1MLE6"/>
    <dbReference type="GeneID" id="9682029"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55685"/>
    <dbReference type="eggNOG" id="ENOG502QSWS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CSSFDMF"/>
    <dbReference type="OrthoDB" id="2017201at2759"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43692">
        <property type="entry name" value="UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43692:SF1">
        <property type="entry name" value="UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21799">
        <property type="entry name" value="MurD-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51984">
        <property type="entry name" value="MurCD N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur ligase central" evidence="7">
        <location>
            <begin position="229"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="647" mass="69776" checksum="011E29B95E7DFE15" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLL6</accession>
    <name>C1MLL6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 28 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_55758</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the VPS28 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056188.1">
        <property type="nucleotide sequence ID" value="XM_003056142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLL6"/>
    <dbReference type="STRING" id="564608.C1MLL6"/>
    <dbReference type="GeneID" id="9682045"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55758"/>
    <dbReference type="eggNOG" id="KOG3284">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CDEFPTV"/>
    <dbReference type="OrthoDB" id="2671at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1130:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 28 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007143">
        <property type="entry name" value="Vps28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017899">
        <property type="entry name" value="VPS28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037206">
        <property type="entry name" value="VPS28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017898">
        <property type="entry name" value="VPS28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038358">
        <property type="entry name" value="VPS28_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03997">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017535">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140427">
        <property type="entry name" value="VPS28 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51310">
        <property type="entry name" value="VPS28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51313">
        <property type="entry name" value="VPS28_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0967">Endosome</keyword>
    <keyword evidence="4 5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS28 N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="VPS28 C-terminal" evidence="7">
        <location>
            <begin position="108"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="206" mass="23753" checksum="B3E6E56C51C24990" modified="2009-05-26" version="1">MEPVQQEERRFLSNKSERKLFDTFANLFALIKTVDKLEKAYVSSAADSDRYEAACAELITKYKTFRSSCADIVPDLHQFMWGNHPRHRLHVGFPATIEHRVSRCGDRDSAVSVAESVHHFIGAMDTLKLNMAAKDQVSPILFDLIQSLYKVPQLPADFTGRALLQRWFDQLEQMRASDRLHEDEVRQLLFDIESAYNTFMQLIGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLX7</accession>
    <name>C1MLX7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_62293</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056840.1">
        <property type="nucleotide sequence ID" value="XM_003056794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLX7"/>
    <dbReference type="GeneID" id="9682737"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62293"/>
    <dbReference type="OMA" id="QVAKPWF"/>
    <dbReference type="OrthoDB" id="10266130at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="204" mass="21189" checksum="C2BAD95BB833F263" modified="2009-05-26" version="1">MAPPSIPPTRGVFVRLGDQVAKPWFPLVIIALSAASCFAIFLSGAVTALFISACVARGKGRFAHVALANALGVALGFGIFIVIVKQRGMDAIRASYPSLFASTHWGYMEGVIARSGWGGVAALAAPLPLHPLVLMGMLSGMSSFSILSAAFAGRFAKYYVMGLVATRGEGVLAAMRGERRSGGKEADDAAPAAAGDEDESKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MME1</accession>
    <name>C1MME1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_32463</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057388.1">
        <property type="nucleotide sequence ID" value="XM_003057342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MME1"/>
    <dbReference type="STRING" id="564608.C1MME1"/>
    <dbReference type="GeneID" id="9682827"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32463"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ISAYWGR"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF117">
        <property type="entry name" value="UNUSUAL PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="134"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="646" mass="70491" checksum="8F053B8CF8AC8343" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMX7</accession>
    <name>C1MMX7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_38988</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057486.1">
        <property type="nucleotide sequence ID" value="XM_003057440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMX7"/>
    <dbReference type="STRING" id="564608.C1MMX7"/>
    <dbReference type="GeneID" id="9682925"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38988"/>
    <dbReference type="eggNOG" id="KOG0838">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NEFTTIR"/>
    <dbReference type="OrthoDB" id="241340at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002938">
        <property type="term" value="P:tRNA guanine ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18092">
        <property type="entry name" value="SpoU-like_TrmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033671">
        <property type="entry name" value="TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43453">
        <property type="entry name" value="RRNA METHYLASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43453:SF3">
        <property type="entry name" value="TRNA_RRNA METHYLTRANSFERASE SPOU TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="6">
        <location>
            <begin position="134"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="285"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="411" mass="45401" checksum="2641854018CEBB2A" modified="2009-05-26" version="1">MDARDDDPNDADAAGLPNRLLRKAETAIQGRTSRVLVVIERCTDEHNYSAVIRTAEALGVQHVWLIDPVDVDLDAVGSDDDDGGGGDDGERDDDDEEEEEEEERAQKKKPGRRTRPWSRTRHGDAARDAHKLFARRANEFTTIREFATTAACVAALREDGRTIWATDLSQRAVCLTESALRAARGDDATSASASVVPEKLAIVFGTESVGCTEEILAAADLRVYLPLRGFADSLNLSVAAALVMHELFRLCPEAIGAMDEAERASLREDWFSRLAAQRIRTPDEARAAKERKRALTKVRHKLNRNTPRTPEVEARMEALRAEEARLKEEEEDATARALVRAKAAVAPFLSRPPATLRDMRRPDDHREAFVCHKIRARNKDNWAGMPAVKGSGGVVDEAWGELAGRKNTGEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN20</accession>
    <name>C1MN20_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_56747</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057027.1">
        <property type="nucleotide sequence ID" value="XM_003056981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN20"/>
    <dbReference type="STRING" id="564608.C1MN20"/>
    <dbReference type="GeneID" id="9682943"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56747"/>
    <dbReference type="eggNOG" id="ENOG502QUAD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MWRTTVA"/>
    <dbReference type="OrthoDB" id="5818554at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051178">
        <property type="entry name" value="TfdA_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779:SF3">
        <property type="entry name" value="(3R)-3-[(CARBOXYMETHYL)AMINO]FATTY ACID OXYGENASE_DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779">
        <property type="entry name" value="DIOXYGENASE RV0097-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="6">
        <location>
            <begin position="8"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="315" mass="34780" checksum="146ABD6D1B349D9A" modified="2009-05-26" version="1">MERPFSASPEARRATLNDALTSSHGLVLLRGGLERITPRELVDISRAIGRGEVETNPGVDAKFLEADAREVQRIGNVVDAITGEPRAMFARAPPLPVDPTCGKTSLTYDPKTRSPVWHTDQAFRDPPPYASVLYCKTAPPPGAGGATIFADVTAAYAALPEDKRLELERYRAVCSYAHHNAKVRKRGTPSYPLLTPEQRAEHPPVYQPLVLTNAATGEKSVYGFNSSVCAVVAEGETLSQEALDIYDLQGEEHESVSRIMYDDLLPHCTRPEFVYEHEWMEGDALIWDNMRTIHAATPLEDGSHAREMWRTTVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNM8</accession>
    <name>C1MNM8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_11302</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057136.1">
        <property type="nucleotide sequence ID" value="XM_003057090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNM8"/>
    <dbReference type="STRING" id="564608.C1MNM8"/>
    <dbReference type="GeneID" id="9682575"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11302"/>
    <dbReference type="eggNOG" id="KOG1680">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AWIDTHA"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43802">
        <property type="entry name" value="ENOYL-COA HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43802:SF1">
        <property type="entry name" value="IP11341P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="151" mass="15832" checksum="90B8010A73B12FD3" modified="2009-05-26" version="1" fragment="single">VAVVTIDAPSTSNAITRPMLVHLARAFRELRDAENPAVRACVLAARGRKAFSAGIDLSAAEDVFKMDANDLTNDIVHQMERCDFLIVGAINGVAVNAGFELALACDVLVCSPRAAWIDTHAKLGLLPSWGLSAKLPRIVGAKAANAVSLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNW9</accession>
    <name>C1MNW9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46623</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057184.1">
        <property type="nucleotide sequence ID" value="XM_003057138.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9682168"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46623"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031982">
        <property type="term" value="C:vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072318">
        <property type="term" value="P:clathrin coat disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172">
        <property type="entry name" value="AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172:SF19">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="472"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="797"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1203"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1305"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1369"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="797"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="866"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="911"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="937"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1203"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1334"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1369"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1432"/>
            <end position="1444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1478" mass="157694" checksum="91D474A44502035D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNY9</accession>
    <name>C1MNY9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_62089</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057194.1">
        <property type="nucleotide sequence ID" value="XM_003057148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNY9"/>
    <dbReference type="GeneID" id="9682077"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62089"/>
    <dbReference type="OrthoDB" id="6152977at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="651" mass="67214" checksum="A0A0F9F9E7DBDBAB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP02</accession>
    <name>C1MP02_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_46633</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056734.1">
        <property type="nucleotide sequence ID" value="XM_003056688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP02"/>
    <dbReference type="STRING" id="564608.C1MP02"/>
    <dbReference type="GeneID" id="9682173"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46633"/>
    <dbReference type="eggNOG" id="KOG4417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CSIHRIP"/>
    <dbReference type="OrthoDB" id="20018at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016891">
        <property type="term" value="F:RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06559">
        <property type="entry name" value="Endonuclease_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2170.10">
        <property type="entry name" value="archaeoglobus fulgidus dsm 4304 superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007581">
        <property type="entry name" value="Endonuclease-V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28511">
        <property type="entry name" value="ENDONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28511:SF1">
        <property type="entry name" value="ENDONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04493">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="220" mass="23058" checksum="94E4C97E88DFAFEC" modified="2009-05-26" version="1" fragment="single">MGATFTFNGAPLTLIGGVDASYPATETDDAVAVACLAVLSFPSLETVRLDFEPFAPAAEYVPGRLADRELPPYLALLRRCPRPLAPQCVFVDGNGVLHPERFGIACRLGVDAATPTIGVAKNLLRVDGVDARARSKRDRDASDVGEVELVDDSGTVVGVALSGHDVAGVVTKPVYVSAGAGMDLATATALTRACSRHRVPEPIRAADVASRAWLREHQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP39</accession>
    <name>C1MP39_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_56136</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057218.1">
        <property type="nucleotide sequence ID" value="XM_003057172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP39"/>
    <dbReference type="STRING" id="564608.C1MP39"/>
    <dbReference type="GeneID" id="9682657"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56136"/>
    <dbReference type="eggNOG" id="ENOG502RRFG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FDMANHD"/>
    <dbReference type="OrthoDB" id="498498at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF154">
        <property type="entry name" value="GRIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="536"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="536"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="563" mass="61506" checksum="B525706FA88F591B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP53</accession>
    <name>C1MP53_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_56150</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057224.1">
        <property type="nucleotide sequence ID" value="XM_003057178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP53"/>
    <dbReference type="STRING" id="564608.C1MP53"/>
    <dbReference type="GeneID" id="9682201"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56150"/>
    <dbReference type="eggNOG" id="ENOG502S4FE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WEAQVER"/>
    <dbReference type="OrthoDB" id="523796at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36052">
        <property type="entry name" value="EXCITATORY AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36052:SF1">
        <property type="entry name" value="EXCITATORY AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="85" mass="9398" checksum="FFEC7EC83D05231A" modified="2009-05-26" version="1">MPFATTATMAGAAMGFGTQLFINALRKLPLLRNPWEHVLWTGGGVWAANAMAEWEVKLTEEVKAMQAERQAANARFMESIKSSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP74</accession>
    <name>C1MP74_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56171</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056772.1">
        <property type="nucleotide sequence ID" value="XM_003056726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP74"/>
    <dbReference type="GeneID" id="9682211"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56171"/>
    <dbReference type="OMA" id="CASAMCE"/>
    <dbReference type="OrthoDB" id="497431at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="484" mass="53622" checksum="0DC8BEE106875EAE" modified="2009-05-26" version="1">MDSEEDATRREVEVTLLAVAPSPTGGDDVEEILGVTDLERDPTKRERRCVRSSVGPQAGRRVRLRIPPSGGRVASVSIARRDVVALVRVGDLSLRAEIKPPLPTDHRADDPPIERQLGSLKADGVAVQLRFARRRRDDAAGETEAGDDGGARSTTTTTTTTTFEYEIIDGAFTADELTMEGIDALHAAGEVAATSARDAAALPQPTARTARSEEIWLPRKLKPDDEGYDERNPEKIAYDPRGKDRIEELLFETRQMAERHERDGRDWCGPLRAKINAKLKKLHALRARAGFIRELRKRLGNANEVVTEEMVRVLKATAIVQQVKHTVDGKVSSVEKEKQVTDGGEAFFDELGVDVDDLEGKTSSELLADLGVTQRACLRAQESANAMHDEITQRYELDRYESGVETRDVLENGVRRVDMEAILGRRAEKEDVDKTLEIPLVERMKLVGGYDVEQMKQDGTFVALPRLADVTGEEAWGLNIDVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPK8</accession>
    <name>C1MPK8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_12066</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057972.1">
        <property type="nucleotide sequence ID" value="XM_003057926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPK8"/>
    <dbReference type="STRING" id="564608.C1MPK8"/>
    <dbReference type="GeneID" id="9683082"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12066"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DGHITMN"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="5"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="71" mass="7695" checksum="D1B8227AB59300D4" modified="2009-05-26" version="1" fragment="single">GGAEITEAEVREAFAAFDEDGDGLLDARDVKSFFEALGQTVSTREASEMLRTVDGDGDGRVNFEEFFDLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPZ6</accession>
    <name>C1MPZ6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_16454</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058036.1">
        <property type="nucleotide sequence ID" value="XM_003057990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPZ6"/>
    <dbReference type="STRING" id="564608.C1MPZ6"/>
    <dbReference type="GeneID" id="9683474"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16454"/>
    <dbReference type="eggNOG" id="KOG0939">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WRANTIY"/>
    <dbReference type="OrthoDB" id="512896at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF429">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SU(DX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="150" mass="15513" checksum="C60EE5D55B1D8533" modified="2009-05-26" version="1">MGGTAKIDVDEWRANTIYEGGYDADSPQVRWLWRLVGKFTPEERTLLLKFVTGSSRMPAGGFAQLQGMNGVRLFEVMRVAAGWTEGGGGGGGGGGGGGGGGGGGGGGSYALPTASTCFNTLRLPAYPSYDVLEQQVTTALRHGVEGFAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ90</accession>
    <name>C1MQ90_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57203</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057716.1">
        <property type="nucleotide sequence ID" value="XM_003057670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ90"/>
    <dbReference type="GeneID" id="9683524"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57203"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="563"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="567"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="637" mass="68462" checksum="F846643FA3CFF962" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQC0</accession>
    <name>C1MQC0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57234</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057730.1">
        <property type="nucleotide sequence ID" value="XM_003057684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQC0"/>
    <dbReference type="GeneID" id="9683540"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57234"/>
    <dbReference type="OMA" id="MISISAN"/>
    <dbReference type="OrthoDB" id="10684106at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="485"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="412"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="276"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="551" mass="57888" checksum="AF8DA56AF8807A9C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQX1</accession>
    <name>C1MQX1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_57443</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057829.1">
        <property type="nucleotide sequence ID" value="XM_003057783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQX1"/>
    <dbReference type="STRING" id="564608.C1MQX1"/>
    <dbReference type="GeneID" id="9683642"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57443"/>
    <dbReference type="eggNOG" id="KOG2519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DGVECEC"/>
    <dbReference type="OrthoDB" id="2959108at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09869">
        <property type="entry name" value="PIN_GEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF59">
        <property type="entry name" value="FI23547P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="2">
        <location>
            <begin position="131"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="703"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="794"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="806" mass="85131" checksum="E9BAB3D13074E670" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR61</accession>
    <name>C1MR61_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_33180</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058248.1">
        <property type="nucleotide sequence ID" value="XM_003058202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR61"/>
    <dbReference type="STRING" id="564608.C1MR61"/>
    <dbReference type="GeneID" id="9683313"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33180"/>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MEDTHIM"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="27"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="443" mass="47054" checksum="3F75A48C3CD0486D" modified="2009-05-26" version="1">MEEARLTPDQPSSSEAAFPPHAPTALRSGEHGEMGRRNSMEDAIARVEDVDVSGRGDDGGPLAFYVICDGHGGSAAAEYVSKYLVKNITADERFRKDPSVAMRDAFSRTDAEFKSVMDADECSGSTALALCVSGSECFVANAGDCRAVLSRHGTAIDLSADQRPSTSVERARIEAAGGYVEDGYINGHLGVARAFGDFHIDGLKGGADGKPGPLIVTPEVETRTLTTQDEFIVLACDGLWDVFSSQNAIDFTRIALRGHNDPEIAARELCNEALRRDSADNVSVIVVCLSRDKPPDKATEHARIAPPRSQFSRTISNEGLSELQRALKSDNEAAKKSPGLQRVRSINPHSGGGGGGEGLSLGHLSNFSEELESLHVDGDDTMELSDDGIRRIRRHSVMDGSGGGEDDHLSPLVECPETGSPYSTIDGDASPHTLLGEHVGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS46</accession>
    <name>C1MS46_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_39933</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058983.1">
        <property type="nucleotide sequence ID" value="XM_003058937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS46"/>
    <dbReference type="STRING" id="564608.C1MS46"/>
    <dbReference type="GeneID" id="9684062"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39933"/>
    <dbReference type="OMA" id="CWVHVRK"/>
    <dbReference type="OrthoDB" id="567237at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009:SF22">
        <property type="entry name" value="LD43819P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="3">
        <location>
            <begin position="61"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="237"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="265" mass="29524" checksum="D375350F5E6984B7" modified="2009-05-26" version="1">MPIDYSKFDNIDTDDDSDDDDARTKKKPQETPSSKPAASAAPSSAASDASAQQHKNFHFDETKLDDWGVKRMRELLHKAVVRDRIAHEDIELDLDVKLVERVITGECWVHVRKGKKVCGYDFDIKLDWAGKVGDGMPIHGFLETNFTVDDDDFDFVFGVKQEVPFKDAVFDALRAVFVRACDRFVKELSEKGPKMEARTGAGWTGEANVQVGQYTKYEEGPDGVKNLQERARAMTVGEGGEGADDHAAGEGNKHQRRLHTSAPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSB2</accession>
    <name>C1MSB2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_33697</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059021.1">
        <property type="nucleotide sequence ID" value="XM_003058975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSB2"/>
    <dbReference type="STRING" id="564608.C1MSB2"/>
    <dbReference type="GeneID" id="9684090"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33697"/>
    <dbReference type="eggNOG" id="KOG1120">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LYIYGMQ"/>
    <dbReference type="OrthoDB" id="333486at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.300.12:FF:000001">
        <property type="entry name" value="Iron-binding protein IscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050322">
        <property type="entry name" value="Fe-S_cluster_asmbl/transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072:SF41">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="3">
        <location>
            <begin position="21"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00057984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="128" mass="14379" checksum="B2FEF2B23F7A96C8" modified="2009-05-26" version="1">MSALREVAKTARSRRVRKQAMELTAAAASRIRELLTKREKQYLKIGVRTRGCNGMTYTMNYADESDKGKFDEVVTHEESGVKVIIDPGALMHVIGTKMDFVEDRLRSEFVFENPNAKGECGCGESFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSH2</accession>
    <name>C1MSH2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58485</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058679.1">
        <property type="nucleotide sequence ID" value="XM_003058633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSH2"/>
    <dbReference type="GeneID" id="9684492"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58485"/>
    <dbReference type="OrthoDB" id="548912at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF52">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="493" mass="53978" checksum="DD374F8A192E03A3" modified="2009-05-26" version="1">MAISRAAADEDKFRKMIAPTVRSSCALLPRETTMSPAGADDDPSKYLGRRVEVHWANDDPPTWYPGVVARYDPRRKDARYRVDYDDGADEWVDFPEPTVRFLDPEPAPEPAATSPAKRKMTVGVKRAAPSTAASPRADPMIGDDISVPIVASAKKGTCKGGADAAGAKKRRPAAASGKKRAKAKANDDGDAAVVDSKCDESLWTRAARATTASPDGALMPSTLKVLETFAGAGGLHMHGDATHGPSGVAVALESVAAIDIVKDACDTYSHNFPGVNVMHIGISRCLATARRLQRLKTRDCDARCDGESCASAPHEPVGELEDVNDDITRVLDFRITDDATHMREEDVRRIKGNKKGSSTKDKQMLDEVTALEVTGKKPLPWIEWLVENHRGDTWWERDSSEGRLEHGARVYMRADEHPEVYEEFAEFDEGSDFEECEYAPFGPHKFPLPGDVHVVTGGPPCQGWSGFNHTRSTSDQLAELMEHPENRLICRFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT21</accession>
    <name>C1MT21_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_57910</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058783.1">
        <property type="nucleotide sequence ID" value="XM_003058737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT21"/>
    <dbReference type="STRING" id="564608.C1MT21"/>
    <dbReference type="GeneID" id="9684222"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57910"/>
    <dbReference type="eggNOG" id="ENOG502RZCC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WARANEC"/>
    <dbReference type="OrthoDB" id="494131at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="420" mass="46058" checksum="5C5BE6022C966135" modified="2009-05-26" version="1">MSPSRPKKRALLVGAGDEIAGDGSTSADLDAGSRLERFAADAPDVFAAHVLSRLDSGDLAVLATVNLKMRDVVFASPVEHDVRDVAAVRRELGRLPNFVGSSSRLAWAKDQRGCPWNAKTFMCIAEGGNVEVAKWAKARGCPWDAWTCAWASSGGHLRMLQWARANGCPWDERACHDAAAGGHLEVLQWARANGAPWDELTCKKAARGGQLEVLQWARANGCPWDVRTCNAAAEGGHLEVLQWARANECPWDEWTCAYAAGEGHLEVLQWARANGAPWDEWTCAFAASGGHLEVMQWACANGCPWDERTCHEAALGGHLEVLKWARANDAPWDEETCHEAAGGGHLEVLKWARVNGAPWDERTCADAARGGHLEVLQWARANDAPWDPEECKARAWIRMHGDVLRWIAAEVRWRPYQGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT55</accession>
    <name>C1MT55_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68060</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058431.1">
        <property type="nucleotide sequence ID" value="XM_003058385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT55"/>
    <dbReference type="GeneID" id="9683869"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68060"/>
    <dbReference type="eggNOG" id="ENOG502RY2Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RQMYNDI"/>
    <dbReference type="OrthoDB" id="44735at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46732">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE LA (LON) DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46732:SF8">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE LA (LON) DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="445" mass="48609" checksum="CB991758F8A65007" modified="2009-05-26" version="1">MTCTMRATPVAFARALTRPAARRGLSSGSHGASSSSSSSPWRRLAPATSASRAPRFFPAPPLPTRNPAAFRVFAGGPDGPSGPISDDERTPTRDYASEISWIARADATKEDEEVDPAAQPDVMVMPVFPLGSTAYMPHSDHVLNIFEPRYRQMYSDILFNGSRRFAVPVSDPKSGRLAAVAPIFYLEDLKEVSEQTADAVKYVCSHKVIGRVRIDRTINDKAASDRSTYLKAVVEPMEDGDDDEDLSTREGILSERFATIIQNQTKLQEPVRFTENLIDTLSASRGEDGLWRLAGLWQSLLQNRIGAKESELSNEIQTLLRNYLAKQGTELQNKVAVQFDALPGDVKAEFTRLQTQYREEAAPMVSAALYPFALLVQCDTHGARLEVFGEMLEEEEARLRAKLALQSLFSSASAPGGEATEEAEVEGTEDADGKKSDDAGGSESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTS5</accession>
    <name>C1MTS5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58533</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059074.1">
        <property type="nucleotide sequence ID" value="XM_003059028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTS5"/>
    <dbReference type="GeneID" id="9684810"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58533"/>
    <dbReference type="OMA" id="NDRCMYF"/>
    <dbReference type="OrthoDB" id="10011777at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="38"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="151" mass="16731" checksum="22AE5F12163F0AAE" modified="2009-05-26" version="1">MATASRSAFITGRALSRAAPTRARRTAGVVRAAKEGRQSLFVTVTVKEGKMDEYNELIQGHITNCFANDRCMYFDYGIPVDGDPNVVHLYEVYEDEAAYKEHKASAHLKDYVEKAEALTSSTTTMKLLTLAQYGSVNCNYAGECELSGEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTT6</accession>
    <name>C1MTT6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_40057</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059079.1">
        <property type="nucleotide sequence ID" value="XM_003059033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTT6"/>
    <dbReference type="STRING" id="564608.C1MTT6"/>
    <dbReference type="GeneID" id="9684816"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40057"/>
    <dbReference type="eggNOG" id="ENOG502QQMS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VKEGYFR"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="107"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="345"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="445"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="464"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="508"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="564"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="577"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="640"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="680" mass="71648" checksum="6030A5767033261F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTW0</accession>
    <name>C1MTW0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58573</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059387.1">
        <property type="nucleotide sequence ID" value="XM_003059341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTW0"/>
    <dbReference type="GeneID" id="9684558"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58573"/>
    <dbReference type="eggNOG" id="ENOG502SYQ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DHPCGPC"/>
    <dbReference type="OrthoDB" id="512205at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025354">
        <property type="entry name" value="DUF4258"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14076">
        <property type="entry name" value="DUF4258"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="168" mass="18368" checksum="9CEECECB18FD1E32" modified="2009-05-26" version="1">MAPPPIPGGRGGGRGRGKGGYKGRMGKRFKKEKDGGDKPKRKKTGFGVVGVLGLFASLLGAMTALAVRETKKTSQKSDDVRRRLLSRPRAYSKHAACRMDCRKVTDEDAENTLHRGALSDRHSTPSARPCPRWALEDGRVRAVWAECRDETRLVTVIDTVTDHPCGPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU85</accession>
    <name>C1MU85_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58707</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059452.1">
        <property type="nucleotide sequence ID" value="XM_003059406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU85"/>
    <dbReference type="STRING" id="564608.C1MU85"/>
    <dbReference type="GeneID" id="9684892"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58707"/>
    <dbReference type="eggNOG" id="KOG1426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF466">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="235"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="486"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="487"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="631" mass="67709" checksum="B67C7D461C7F345B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUG6</accession>
    <name>C1MUG6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_69563</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059491.1">
        <property type="nucleotide sequence ID" value="XM_003059445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUG6"/>
    <dbReference type="GeneID" id="9684931"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69563"/>
    <dbReference type="OrthoDB" id="10688918at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="521" mass="50643" checksum="85DD9FE2AB416DFF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV31</accession>
    <name>C1MV31_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59038</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059299.1">
        <property type="nucleotide sequence ID" value="XM_003059253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV31"/>
    <dbReference type="STRING" id="564608.C1MV31"/>
    <dbReference type="GeneID" id="9684739"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59038"/>
    <dbReference type="eggNOG" id="KOG2102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NEPRCAV"/>
    <dbReference type="OrthoDB" id="2285229at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056404">
        <property type="entry name" value="HTH_RNase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF42">
        <property type="entry name" value="RIBONUCLEASE II, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23161">
        <property type="entry name" value="HTH_RNase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="2">
        <location>
            <begin position="129"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="636" mass="68867" checksum="378A49B7215D2CCF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV52</accession>
    <name>C1MV52_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_40349</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059606.1">
        <property type="nucleotide sequence ID" value="XM_003059560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV52"/>
    <dbReference type="GeneID" id="9684755"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40349"/>
    <dbReference type="OrthoDB" id="1935339at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="76"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="128"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="219"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="248" mass="26617" checksum="721D37BF2E4709D5" modified="2009-05-26" version="1">MASRKRARPSSSSLPLETPGVRHAWWGRDRDRVVDDDGGGGGADDAARAILDPLPLPFSAARTMGGKLASNARARCKLCDGEQSRDDMALLSGCNHALCVDCVEGWATRRARNCPICKVAFDGWYHGGDGGDGARGEDGGDGENGENGGKARERRFHKLPPLPEGGVVARTPARSSRALTFDLADAKKPRRRGALFSSEPEPETETEGTEDGEDDDEMREALRMEASAAKKERSRVGSARENDARVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV67</accession>
    <name>C1MV67_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_18187</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059322.1">
        <property type="nucleotide sequence ID" value="XM_003059276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV67"/>
    <dbReference type="STRING" id="564608.C1MV67"/>
    <dbReference type="GeneID" id="9685054"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18187"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FCGRELD"/>
    <dbReference type="OrthoDB" id="10250130at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019760">
        <property type="term" value="P:glucosinolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435:SF4">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="355" mass="36944" checksum="9BDC7B9CE02B3EC8" modified="2009-05-26" version="1">MAPDPHHVTWRARSPANAPIARSSHGASVINNTLYVFGGEHVARTPIDSVVHALDLTDPNAAFVAIDGGANAPPPRVGHAQASIENVFYVFGGRRGVEMNESPLNDLWAFDVESREWTDLSGGAGDVPCPRSFHVATAARGKLYVFGGCGPADAGRLADLHEYDVASKTWTKLPGSDAIESRGGAGFSSTTDGSTLVIAGGFAGREMKDIHAYDIASKTWRARPAPAPLRPRSVWPVMAFTCYGDHVIGFGGEVDPSERGHDGAGGFANDVVAIEVRTGDAKTLPLGRGGLGAGVGGGDGEEETAVPAPRGWTAAAEWRREGAIVLFGGLSGSDAAPERLGDVQIGYIDRGGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVB6</accession>
    <name>C1MVB6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59132</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059638.1">
        <property type="nucleotide sequence ID" value="XM_003059592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVB6"/>
    <dbReference type="GeneID" id="9684787"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59132"/>
    <dbReference type="OrthoDB" id="498291at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="86" mass="9375" checksum="E476ADFEDC55BE23" modified="2009-05-26" version="1">MNTDTIIRDNAAYLASAGQARSSWSPDTVPDGKSSKGRMLEGYLQNAERCVVKEGYGAFNEMDAETRKEWKAISCTQGLVSPADPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVN2</accession>
    <name>C1MVN2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">3-oxoacyl-[acyl-carrier-protein] synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MICPUCDRAFT_49639</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15 17">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060067.1">
        <property type="nucleotide sequence ID" value="XM_003060021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVN2"/>
    <dbReference type="STRING" id="564608.C1MVN2"/>
    <dbReference type="GeneID" id="9685505"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49639"/>
    <dbReference type="eggNOG" id="KOG1394">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QAGWMPT"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000027">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier-protein] synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004970">
        <property type="entry name" value="PRK06333.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005589">
        <property type="entry name" value="PRK07314.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF336">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11 15" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 15" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="18">
        <location>
            <begin position="52"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="16">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH56019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="467" mass="49147" checksum="C771A469E03134EE" modified="2009-05-26" version="1">MAALASSTIIGARGVVANRRVISARTSAGSGSRAAGRRTIVVVNMARETDPKKRIVVTGMGLCSVFGNDYDKFYDKLLAGESGVDMIDRFDTEDFPTKFAAQIKDFDNEGFIDKKNARRMDNCLQYALVSGNKALLDAGLDDDAIEKLDKTRVGVLAGSGMGGLTVFQDGVKALVEKGPKKITPFFIPYAITNMGGALLAIEKGFMGPNYSISTACATANYCFHAAANHIRKGEADIIVAGGVEAPIIPVGLGGFVACRALSSNNDNYKGASRPWDKGRDGFVMGEGAGLLVLESLESAQKRGARIHAEYLGGAVTCDAHHMTDPRPDGSGVGLCITKAVEDAGIDISEINYINAHATSTLVGDVAEVNAVKKAFNNKLDGVKMNGTKSMVGHCLGAAAGVEAVATIMAIKTGWLHPTINQEDSIDEVADIDTCPNVKVEHEVKVAISNSFGFGGHNSSCVFAPFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVP8</accession>
    <name>C1MVP8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein light chain roadblock</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ODA-LC7B</name>
        <name evidence="12" type="ORF">MICPUCDRAFT_59459</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
            <location evidence="1 10">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GAMAD family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060077.1">
        <property type="nucleotide sequence ID" value="XM_003060031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVP8"/>
    <dbReference type="STRING" id="564608.C1MVP8"/>
    <dbReference type="GeneID" id="9685227"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59459"/>
    <dbReference type="eggNOG" id="KOG4115">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NNSTIEY"/>
    <dbReference type="OrthoDB" id="9985637at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.30:FF:000011">
        <property type="entry name" value="Dynein light chain roadblock"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016561">
        <property type="entry name" value="DYNLRB1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009998">
        <property type="entry name" value="DLC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 10" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="11">
        <location>
            <begin position="4"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH56029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="109" mass="11984" checksum="E6972AFCCD4E8988" modified="2009-05-26" version="1">MSEVEATLQRINGHKGVLGTIIVNDEGEPIRATTICDADGTPVEDQEGTVAKYAELIPQLASMARSMVRDLDPQNNLQFLRIRSKQHEIMVHSDAEFTLIVIQNPAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVY6</accession>
    <name>C1MVY6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59558</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060120.1">
        <property type="nucleotide sequence ID" value="XM_003060074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVY6"/>
    <dbReference type="STRING" id="564608.C1MVY6"/>
    <dbReference type="GeneID" id="9685272"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59558"/>
    <dbReference type="eggNOG" id="KOG1823">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AFWQEAY"/>
    <dbReference type="OrthoDB" id="360653at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052575">
        <property type="entry name" value="SSU_processome_comp_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046523">
        <property type="entry name" value="UTP20_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695:SF11">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20416">
        <property type="entry name" value="UTP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20" evidence="2">
        <location>
            <begin position="20"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="845"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="847"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1043"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1062" mass="114792" checksum="EBC0BBF5CC423AC9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWF1</accession>
    <name>C1MWF1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_12148</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060205.1">
        <property type="nucleotide sequence ID" value="XM_003060159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWF1"/>
    <dbReference type="STRING" id="564608.C1MWF1"/>
    <dbReference type="GeneID" id="9685643"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12148"/>
    <dbReference type="eggNOG" id="KOG0230">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="443981at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000285">
        <property type="term" value="F:1-phosphatidylinositol-3-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748:SF7">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="5">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="64" mass="7250" checksum="887809FCA05EC8A4" modified="2009-05-26" version="1" fragment="single">PRFWIDERACKSCYECDRRFGPTARKHHCRACGRVFCARCSSNALPPDRDPDGAPARVCGVCYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWF2</accession>
    <name>C1MWF2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59744</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059913.1">
        <property type="nucleotide sequence ID" value="XM_003059867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWF2"/>
    <dbReference type="STRING" id="564608.C1MWF2"/>
    <dbReference type="GeneID" id="9685644"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59744"/>
    <dbReference type="OMA" id="FRNDSHA"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="282"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="424" mass="46104" checksum="97556DB9B5742140" modified="2009-05-26" version="1">MSAVSSGALARAQWGAVRGLNRASETVRPRRARRRRANEFIPIRNAASRTRVEMKRGSLTRPPRRPPSPPQQPSSTARPRGAAVIRCGRSKKAKEAAKADKKAGKKASPAVSKQAKDKARKAAAAAMREVVSKQGRAYDRIVKEMDRDQYREYVLSVRHAPPEDSTSAPIAVLGDWLPICEVVVADKRAYEAQKFFKENNMTIPETEQQSVTAEQIEGVPAIKAMIPCLGPDIIGMTHAMAGAAVKDVDVSELEFGIEQWGSFENAVDGLEAQASSKARFAAAAKVLSVSVDDDAKDVKARYRKLIATEHPDRNPDASLEKFNAIKEAYELMSDRGGQSGATFEGLGDKAKRDFVTLEGVHAGVTSGGGAVSCDVDTNAIEVALRSLTIYDRIKTCFSARNVSLQARSIHWFPYDRVGEVDADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWP4</accession>
    <name>C1MWP4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Laminin-type egf-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_70859</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059662.1">
        <property type="nucleotide sequence ID" value="XM_003059616.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MWP4"/>
    <dbReference type="GeneID" id="9685401"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70859"/>
    <dbReference type="eggNOG" id="KOG1218">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1225">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HGTCQYD"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.300.10">
        <property type="entry name" value="Tie2 ligand-binding domain superfamily"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051216">
        <property type="entry name" value="Teneurin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11219">
        <property type="entry name" value="TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11219:SF69">
        <property type="entry name" value="TENEURIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00011">
        <property type="entry name" value="EGFLAMININ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 4" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910533" evidence="5">
        <location>
            <begin position="41"/>
            <end position="2729"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="531"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="765"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="955"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="1746"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="2615"/>
            <end position="2652"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="560"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="789"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="983"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="1770"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="2642"/>
            <end position="2651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2729" mass="293406" checksum="D2D0C9B42CAB316F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWR2</accession>
    <name>C1MWR2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_40446</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059969.1">
        <property type="nucleotide sequence ID" value="XM_003059923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWR2"/>
    <dbReference type="STRING" id="564608.C1MWR2"/>
    <dbReference type="GeneID" id="9685130"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40446"/>
    <dbReference type="eggNOG" id="ENOG502S9MK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="78101at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055310">
        <property type="entry name" value="CEP112"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027831">
        <property type="entry name" value="DUF4485"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18871">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 112 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18871:SF2">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 112 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14846">
        <property type="entry name" value="DUF4485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4485" evidence="2">
        <location>
            <begin position="50"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="496" mass="53181" checksum="A7C2C009F601A0B6" modified="2009-05-26" version="1">MSFSFPGVREDFFRAGVKLSPARGERASYGASPQLGPGHGTLEHERRCALDDAFRNATHEISTRLAMVARAPRIRCEAWIKKLSEPEKNAAWKKNRNNHARLLLHQLGVGRLEAPFDKMPYDGRLAMLPPHALYCLAFGGGGGGGGLSGGSGRWNARRASKECSNDRRRGPFLESVGKTSYRSLLDDFGPIGGGPNSPTTRASLEDLLRRAEASCAMTAMTTSADPAAAAYSAAMEDIAVPLSERTKRATDAAKRAKADADADASASGGGFSRSKSKTIVTPTKRERGRGSTTGGAGGGGGGVVVVGDSEHVNELGAIRERCRELEYRCDARAFSFLSSRANDDDQSRSSTSSSTLTDRGPPRVVRLGRAEEIATASRRESELAKEALLKTQKAKGDELKALRIAHKKEIDQLIETFERRRSGDVGDMLRGDAAGTGTGTGTGGTPRRAAARSLPAYSPIPKDPRKSAEEFESYLKKFQEQTAELKLHAKFATAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWU6</accession>
    <name>C1MWU6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_18672</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059984.1">
        <property type="nucleotide sequence ID" value="XM_003059938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWU6"/>
    <dbReference type="STRING" id="564608.C1MWU6"/>
    <dbReference type="GeneID" id="9685150"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18672"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KINTECG"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46463:SF10">
        <property type="entry name" value="OS01G0926200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46463">
        <property type="entry name" value="ZINC FINGER, RING/FYVE/PHD-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="5"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH55936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="62" mass="7202" checksum="98A5BFDCDAC3811B" modified="2009-05-26" version="1" fragment="single">DEDSCPICFEAYDDENPKMPLRCEHHFHLGCVFEWFERSELCPVCEEKMEFAPSVGMTLSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWY9</accession>
    <name>C1MWY9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65339</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059715.1">
        <property type="nucleotide sequence ID" value="XM_003059669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWY9"/>
    <dbReference type="GeneID" id="9685093"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65339"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="488" mass="53859" checksum="FB8168DD36D2F93F" modified="2009-05-26" version="1">MHRSHAERELEIRGHEWTRRNEAAAAKLASDALEHATNAVEAETDRLPLPDLAASLREKIERIARRHVDEFNAKTSPVADTAAAQDALIELKKTNAERLASSLEQNARQWHKALAPVSEAALETLNFDRTCVRAIRAAWSVTDAKLNADAVRRCAREIIPWALKRDAANAWIDAFEHRRAEIIAEHSRSSLLRKRPRNVMIVNMTSATVREVAKVFVNDDVSERLAAARVKFRCVLLTTLCVVVASAWLHVTSKPRHRRVDVSDNDVTDEDVDDAFVPDVDADAPGSDRAWVTIDREEAAAAEAAAAAAADAERVVAADADITPPRAKTPTPPHLVDLTGGDANLPNPVVFNATQPLPDEDAGEERFDLVDGTESDSPGWAEISPPRSPTPPPPLQMTVSDIMREINRVRDGDADAMARVLAFHVHPDVRHLVSAAETHSMGGADARTVAEWHVRVLGYVRLRTDDDEEAWLRAPYVTSVLRRYADRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXJ4</accession>
    <name>C1MXJ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_18994</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the mTERF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060703.1">
        <property type="nucleotide sequence ID" value="XM_003060657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXJ4"/>
    <dbReference type="STRING" id="564608.C1MXJ4"/>
    <dbReference type="GeneID" id="9685845"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18994"/>
    <dbReference type="eggNOG" id="ENOG502QYF3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TRASECD"/>
    <dbReference type="OrthoDB" id="431485at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.70.10">
        <property type="entry name" value="Transcription termination factor 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003690">
        <property type="entry name" value="MTERF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038538">
        <property type="entry name" value="MTERF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02536">
        <property type="entry name" value="mTERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0806">Transcription termination</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="129" mass="14478" checksum="AEC82969134F6357" modified="2009-05-26" version="1">MDLVGVDDEKAEKTLIRAFGWGAQSYWRNEKTEEIPDADAVEARIAYLVEIGIAEDKVAEILTKVPEVLGCDVAERLEPNVAHIEKNYFMKRGTKNFANYILRVPQVLGNNLDCVGDCAGECNRCWARC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXM5</accession>
    <name>C1MXM5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_60215</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060423.1">
        <property type="nucleotide sequence ID" value="XM_003060377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXM5"/>
    <dbReference type="GeneID" id="9685861"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60215"/>
    <dbReference type="OMA" id="CIASAWH"/>
    <dbReference type="OrthoDB" id="5981480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="14"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="59"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="412" mass="45812" checksum="2725CF40A7B18135" modified="2009-05-26" version="1">MSTLTKRRASAETCANCGKTSAKLLKCLGCKSALRGRRYCDKKCQKKHFSKEHKDECRLVDLKAAADDAKDAYMKAMRKAEKEIAARDRDKANKHFREAIEACEDARERYKKLGPRALGMELELCVTLCTCHVNLGEYDAAEPYVEAALLAGEVAKTVKIEPDGVEEPLWCGQGQRICGESTTDADGDPRATQETYDDMIEKCIASAWHARHGARMSAAIKGEIIAQCAVCGEDVEGLEADPNLLTCDALSCRHLVHAKCLPNGMADFRPRDRGLGGGDHPDVVTCKICVETGAPRYKNGRSFTEIREDEKREKAEKRNEKKFNEMFGDPTSDEPAAGMFRRESATPEEAREAVLVVQERMRHLINDRGLPDEKKEEYGKMFADAGYDLDKIMTLDPGLEFGGLPPRARGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXU4</accession>
    <name>C1MXU4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60292</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060454.1">
        <property type="nucleotide sequence ID" value="XM_003060408.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9686193"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60292"/>
    <dbReference type="OMA" id="VECEDSI"/>
    <dbReference type="OrthoDB" id="10693176at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="965"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1758"/>
            <end position="1788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="982"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1760"/>
            <end position="1774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1908" mass="191292" checksum="9BCE3B0FB8F65F72" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYM9</accession>
    <name>C1MYM9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome c peroxidase, mitochondrial</fullName>
            <ecNumber evidence="5">1.11.1.11</ecNumber>
            <ecNumber evidence="13">1.11.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MICPUCDRAFT_34503</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.11" evidence="5"/>
    <dbReference type="EC" id="1.11.1.5" evidence="13"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060303.1">
        <property type="nucleotide sequence ID" value="XM_003060257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYM9"/>
    <dbReference type="STRING" id="564608.C1MYM9"/>
    <dbReference type="GeneID" id="9686033"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34503"/>
    <dbReference type="eggNOG" id="ENOG502QR1E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KMTKNYP"/>
    <dbReference type="OrthoDB" id="2859658at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016688">
        <property type="term" value="F:L-ascorbate peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="17">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00039063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH55072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="279" mass="30527" checksum="1152F71C4589E23D" modified="2009-05-26" version="1">MKKDADFGPTMVRLAWHSSGTYDKMTKTGGNGGGTIRFKEELAHGGNAGLDKAVKRLEPIKKRHPDVRRVPIYTGPHTTAWADLIAYVGVVSIETMGGPAIPFAYGRVDEMDPGKVTPDGRLPDADKGDGPGPKTRAGIREVFNRMGFDDQEIVALSGAHALGRCHADASGYVGPWSGTPTLFNNSYFVLLKGLKWTPNDKAAKFQARSIAHWSPYDRYTDPSGNLMMLPSDIALIEDPKFKKYVDVYAKDQKKFFDDFSKAFNKLETLGTSGLTPLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ63</accession>
    <name>C1MZ63_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_7301</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061159.1">
        <property type="nucleotide sequence ID" value="XM_003061113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ63"/>
    <dbReference type="STRING" id="564608.C1MZ63"/>
    <dbReference type="GeneID" id="9686343"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7301"/>
    <dbReference type="eggNOG" id="KOG1225">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000001">
        <property type="entry name" value="Tenascin C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="2">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="90" mass="9722" checksum="FDC8D21D54742B87" modified="2009-05-26" version="1" fragment="single">CPKDCSRHGSCVYNFCVCDTGYTGFDCSNVSCPDDVCYFDYLGHSQVCDQCNNRGICNGFTGSCECQFPASGESCRAFDCLNDCNGNGIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZG6</accession>
    <name>C1MZG6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_28304</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060951.1">
        <property type="nucleotide sequence ID" value="XM_003060905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZG6"/>
    <dbReference type="STRING" id="564608.C1MZG6"/>
    <dbReference type="GeneID" id="9686654"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_28304"/>
    <dbReference type="eggNOG" id="ENOG502RZX4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MAANPKY"/>
    <dbReference type="OrthoDB" id="10267664at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058127">
        <property type="entry name" value="DedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032818">
        <property type="entry name" value="DedA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008102">
        <property type="entry name" value="PRK10847.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30353">
        <property type="entry name" value="INNER MEMBRANE PROTEIN DEDA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30353:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="7">
        <location>
            <begin position="47"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="223" mass="24182" checksum="6A12B6C970891967" modified="2009-05-26" version="1">MWKKAIGWVLHLDKHLAGMFASYGTIAYAILFAIVFCETGLVVTPFLPGDSLLFATGALGASGALNFPLTMAMLFSAAVLGDAVNYGVGNWAGANFMVKYPKVFKKEYVEKTKKFYEKYGGKTVVMARFFPIVRTFAPFVAGVANMTYATFFTYNVMGAAVWICSFMSMGYFFGQIPAVQENFALTVIGIIVLSLVPVIVEIINAKKEESESESEGGEAAAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N063</accession>
    <name>C1N063_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_70812</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061073.1">
        <property type="nucleotide sequence ID" value="XM_003061027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N063"/>
    <dbReference type="STRING" id="564608.C1N063"/>
    <dbReference type="GeneID" id="9686779"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70812"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MYTGSAL"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000281">
        <property type="entry name" value="Cyclin-dependent kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF254">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="9"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="121"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH54723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="442" mass="50609" checksum="A1707FF244465F7E" modified="2009-05-26" version="1">MGHSINEAYEKLEKIGQGTYGKVYKARDRSTGRLVALKKTRLEVRVSFSRAFARRARRRRPRSGRRCRGFFCSKPRAMVFIAGGTAARCARSRGRASRASRLSRDARPLRVHEGSARLRYPRTRSNRARRGRFRGEATREKKARPTRALTRPHPPPRLSPRHQMEEEGVPSTALREVSLLQMLSESAFIVRLLKVEHVEEDGKAMLYLVFEYLDQDLKNFMDLTGRGPANPLAKSVVQDFMYQLCLGCAHLHRHGVMHRDLKPQNLLVDKAKNVIKVADLGLGRAFSVPVKSYTHEIVTLWYRAPEVLLGGSHYSTPVDIWSVGCIFAELARKQPLFPGDSELQQLLHVFKLLGTPSEETWPGVTRLRDWHEFPQWQAQDLSKVIPQLDAHGIDLMKKMLVYDPAKRIHATEALEHPYFDSLDKSRYAKIEASFEKENRKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N064</accession>
    <name>C1N064_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_60986</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061074.1">
        <property type="nucleotide sequence ID" value="XM_003061028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N064"/>
    <dbReference type="STRING" id="564608.C1N064"/>
    <dbReference type="GeneID" id="9686513"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60986"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LTDIMEP"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11046">
        <property type="entry name" value="CYP97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="503"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="557" mass="61678" checksum="A09572D9609564D4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0P3</accession>
    <name>C1N0P3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_8530</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061422.1">
        <property type="nucleotide sequence ID" value="XM_003061376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0P3"/>
    <dbReference type="STRING" id="564608.C1N0P3"/>
    <dbReference type="GeneID" id="9686862"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8530"/>
    <dbReference type="eggNOG" id="KOG4161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HALRWWY"/>
    <dbReference type="OrthoDB" id="10265068at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045138">
        <property type="entry name" value="MeCP2/MBD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074:SF0">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN PROTEIN 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074">
        <property type="entry name" value="METHYL-CPG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="164" mass="18086" checksum="71E2EBC68B9F23DA" modified="2009-05-26" version="1" fragment="single">WAPPRSPFGLLEEILFEDEWKLLTACMLLNCTTRLQVDRALWRLFLLAPTPEEARRTGLDAIEDVLAPLGLHRKRARAFVRLSEDYLAATRPRGEALEANGGGGGGDGGLFSTRTKLAAPAASLHGVGAYASDAHAMFCDGLMGVAPRDHALRWWYAWAVERRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0P7</accession>
    <name>C1N0P7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51101</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061426.1">
        <property type="nucleotide sequence ID" value="XM_003061380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0P7"/>
    <dbReference type="GeneID" id="9686866"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51101"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="106" mass="10795" checksum="BAEF5DC2023AA6F4" modified="2009-05-26" version="1">MPRHIAHFHSVVELDASAGNGVVGDARGVAPVVVACASPDSLAPNQYRRGVAAAFASCHVVNGMRRVFGVVRAAAVGSARRPSGVCGGGGGDDDARGRIRKPTEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0V0</accession>
    <name>C1N0V0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Molybdate synthesis cofactor protein CNX5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CNX5</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_51160</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061701.1">
        <property type="nucleotide sequence ID" value="XM_003061655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0V0"/>
    <dbReference type="STRING" id="564608.C1N0V0"/>
    <dbReference type="GeneID" id="9686896"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51160"/>
    <dbReference type="eggNOG" id="KOG2017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10261062at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00757">
        <property type="entry name" value="ThiF_MoeB_HesA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000033">
        <property type="entry name" value="Adenylyltransferase and sulfurtransferase MOCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF102">
        <property type="entry name" value="ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="5">
        <location>
            <begin position="385"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="511" mass="54373" checksum="B922DABC4B4D6350" modified="2009-05-26" version="1">MPAPSSKRRRTSSSSADADAADADADAALPPAARWTGALSSADASRYARHVSLPSFGALKQAALHRARVLIVGLGGLGSPASMYLVSSGLGSVTLADADVVELSNIHRQIAHRESAVGLAKVASAAATLRAMNSRCDVRTVEARLAPANALDLVRGHDVVLDCTDDVKTRYVISDACASAGVPLVAAAAVGTEGQLTVYCRASAKSVGGVAANTSEKETVAALPLDEEEEEVPPCYRCVFPTPPATRDCASCAGSGVLGPVPGVMGVLQATECIKVLTKHLGRGGGERTLAGRLLMYDAFGGGSMFTHVKLRKRRADCVACGADGTSSGGAWMKTYDYDAFINGNNACAAVKKEAGEEGDGRELYARNLERITPTELREMLTTPTGRGLDVVDVRPRGLYDAAALPGARHVSEYVFPNLWCERPDVMNAAWDRKKPTIVFVCSRGIASKRAAEKYAREIYDEYTTLRDERRKGRTVYGEPELPENMVRILDVVGGMERWRADVDPTFPKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0Z1</accession>
    <name>C1N0Z1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51200</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061480.1">
        <property type="nucleotide sequence ID" value="XM_003061434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0Z1"/>
    <dbReference type="GeneID" id="9687157"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51200"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="203" mass="21733" checksum="83E42FB4CB7326B9" modified="2009-05-26" version="1">MQRSHQARKHRTQHDKTEEGRWDAGPIPAENPSKPSRRKTVRLGLGLDGKAEVFIVNKRVGEESPVGSAMNLIHPADASGPGAGPSPFKRDAADAGAPGTRSAGDGSVRAPRESSGESSSDITEEDDDIASAVKATLRSLNEYEHEHAPGRGDEKAGATRGWNAELASRQKSRNLDDVLSASDRETMLRCVLYTGSHTTPSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N178</accession>
    <name>C1N178_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_9699</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061765.1">
        <property type="nucleotide sequence ID" value="XM_003061719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N178"/>
    <dbReference type="STRING" id="564608.C1N178"/>
    <dbReference type="GeneID" id="9687204"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9699"/>
    <dbReference type="OMA" id="WEAGWQD"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15241:SF304">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15241">
        <property type="entry name" value="TRANSFORMER-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="2"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="75" mass="8397" checksum="420C9907391ED2A0" modified="2009-05-26" version="1" fragment="single">GFALYVSNVAWEAGWQDLKDHFARFGRVSFADVARDRDTGRSLGRGIVRFDDEASARRAIVYGNGTVFMGREINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1D6</accession>
    <name>C1N1D6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_3958</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lariat debranching enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061797.1">
        <property type="nucleotide sequence ID" value="XM_003061751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1D6"/>
    <dbReference type="STRING" id="564608.C1N1D6"/>
    <dbReference type="GeneID" id="9687236"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3958"/>
    <dbReference type="eggNOG" id="KOG2863">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CHGEIET"/>
    <dbReference type="OrthoDB" id="494375at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008419">
        <property type="term" value="F:RNA lariat debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00844">
        <property type="entry name" value="MPP_Dbr1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000035">
        <property type="entry name" value="Lariat debranching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007708">
        <property type="entry name" value="DBR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041816">
        <property type="entry name" value="Dbr1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849:SF0">
        <property type="entry name" value="LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849">
        <property type="entry name" value="RNA LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05011">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="13">
        <location>
            <begin position="1"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Lariat debranching enzyme C-terminal" evidence="14">
        <location>
            <begin position="242"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF05011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH54427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="294" mass="33035" checksum="B707D9039B06DE74" modified="2009-05-26" version="1" fragment="single">MKIAVEGCCHGELDKIYAAMKHLERAEGIVIDLLICCGDFQAIRNVDDVECMSVPNKYKELGTFHSYYSGAKVAPYPTLFIGGNHEASNYLWELYHGGYVAPNVYYMGHAGVINFGDLRVGGLSGIFKGGDYRKGHHERAPYAGHDVKTAYHVREFDVQRLAMLKEHVDVFLSHDWPRGVARHGEMDDLIRKKKFLADELRSNTLGSPPGETLLHALKPSYWFSAHLHVKFAAMVRHHGGGVTKFLALDKCLPRRDFMQIVDLPEKDASGGFRLDPEWLSIVKANHLAQSLTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N254</accession>
    <name>C1N254_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_29032</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).</text>
            <dbReference type="EC" id="3.4.21.92"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062231.1">
        <property type="nucleotide sequence ID" value="XM_003062185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N254"/>
    <dbReference type="STRING" id="564608.C1N254"/>
    <dbReference type="GeneID" id="9687472"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29032"/>
    <dbReference type="eggNOG" id="KOG0840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TIHMHPT"/>
    <dbReference type="OrthoDB" id="2017408at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF11">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="181"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="195" mass="20589" checksum="E8B420ADF45CF344" modified="2009-05-26" version="1">MGQRRIFLNGRVDDKSAHSLVGKMLFLDAVDPETPIVLYVNSGGGVVTSGLAIYDVMQHVRPPVYTVCIGHAESMAAVLLCAGEKGHRYVLPNARVMVHQPHHVISGQTTDILIKATKAEHTRTTLRDIIAKHSGRSAGEVIGVLERDTYMTAAEAVTFGLADEVITHIGELGVPTKVPSGDGGGGGEKASNGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N265</accession>
    <name>C1N265_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_51864</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062236.1">
        <property type="nucleotide sequence ID" value="XM_003062190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N265"/>
    <dbReference type="GeneID" id="9687478"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51864"/>
    <dbReference type="eggNOG" id="KOG3021">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FIVMDHL"/>
    <dbReference type="OrthoDB" id="496295at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102193">
        <property type="term" value="F:protein-ribulosamine 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="166"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="182"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="391" mass="42667" checksum="E17CC0842FD4EE13" modified="2009-05-26" version="1">MASVAPPRVAVPFPRARARARSRRASAAASASASSHPPGGVAEWIETNLPDAGAVTRSISLGGSGWAEFSSHECESGAKYFAKTSRRDAEMFMGEGAGLSALHATATLVIPRVYHAGSLPEGSREGRSFIVMDHLGAFCTPVPVRPRPRGERRSLRTFSPGVSLRPGSLAFNPDAPRRLSTPLMTPFNSTPTFARTERPSDFGARGDQAEFGASLARMHLAEPAVAEARDDGMFGFSVNNTIGDTPQPNAWGSDWVEFFREKRIRHQLKLARDSTLSELGEAVVENMPRWFAPCGEIRPSILHGDLWSGNIGTVGGRPSAFDPAVYYGHSEAEFGMSWCAGFTQAMNPKTEEHFEERRKLYQLYHYLNHYNLFGGGYKGTCVDIMKSLADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N335</accession>
    <name>C1N335_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_48511</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062539.1">
        <property type="nucleotide sequence ID" value="XM_003062493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N335"/>
    <dbReference type="GeneID" id="9687979"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48511"/>
    <dbReference type="eggNOG" id="ENOG502QUBG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498055at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058936">
        <property type="entry name" value="At4g15545-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058935">
        <property type="entry name" value="At4g15545-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47383:SF8">
        <property type="entry name" value="OS01G0768300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47383">
        <property type="entry name" value="OS03G0659800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25972">
        <property type="entry name" value="At4g15545_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="At4g15545-like C-terminal" evidence="3">
        <location>
            <begin position="226"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="149"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="163"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="620" mass="65068" checksum="15FC2EF3E542792F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3C9</accession>
    <name>C1N3C9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_42163</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062587.1">
        <property type="nucleotide sequence ID" value="XM_003062541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3C9"/>
    <dbReference type="STRING" id="564608.C1N3C9"/>
    <dbReference type="GeneID" id="9687798"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42163"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="121"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="287"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="542"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="565"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="601"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="639"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="648" mass="69081" checksum="FFFCDEB131752F83" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4F2</accession>
    <name>C1N4F2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_42406</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062779.1">
        <property type="nucleotide sequence ID" value="XM_003062733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4F2"/>
    <dbReference type="STRING" id="564608.C1N4F2"/>
    <dbReference type="GeneID" id="9688429"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42406"/>
    <dbReference type="eggNOG" id="KOG1426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498720at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF408">
        <property type="entry name" value="OS09G0560450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="354"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="4">
        <location>
            <begin position="355"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="411"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="465"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="517"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="776"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="828"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="257"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="872"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="876"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1003" mass="103716" checksum="B27ADE79BAC8288F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4G5</accession>
    <name>C1N4G5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52548</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062785.1">
        <property type="nucleotide sequence ID" value="XM_003062739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4G5"/>
    <dbReference type="GeneID" id="9688436"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52548"/>
    <dbReference type="OMA" id="NRERTYV"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="453" mass="48281" checksum="10E2843C0CC32CF5" modified="2009-05-26" version="1">MATRRRTWTRVGRDVSASTTASTTTTTTTTTTPTRETARFPPKPPQVVTARDLSESDEAAVSRARRANHAVLGGVALAAVVVLLAKRRKNDAKRRDDDDDDDADAAAAKLASEQPRALDVDGAATPPRGAKMTDSAKVTPASGVDAAAAPRPPARRAKKNLFPTRSAATANASSEVEPYESPARDDADAMMTEVVTRAERGEAEVIGDGSNLATIDVLASPPRSPSSDAIAAVVSAKRVLSRAKASRRLRQPGELRVNVLGCRVADFIARRASLDAREEAEERWRDDADALRDADVAARFALKIECDALGDGERIVRGTTRTKYLDYHDEKPGSAASIAAGKNTVTFNQGMTFALPADEKRGGSLRLKLASGCAEHAKARDDDDNLRAPRGSTSRKTLCMSGLVVREVLRAAPVTKEFALYDVDGKEAGHALLSFEWRHAPFEASEADATAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4H2</accession>
    <name>C1N4H2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52555</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062790.1">
        <property type="nucleotide sequence ID" value="XM_003062744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4H2"/>
    <dbReference type="GeneID" id="9688438"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52555"/>
    <dbReference type="OMA" id="TTETWEA"/>
    <dbReference type="OrthoDB" id="10669274at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="435" mass="45672" checksum="4793D06FB8A7A121" modified="2009-05-26" version="1">MSSAALASSSSAFASRRVARASSLVRRAARRRVVVVARSSSNLTTSPPGASSDGGDADADARRRDERTDDVARAVLEFHAAEGNGNGARGRGGERVVPLASFARRYGWSESRAEGVLWQSDVPARAFGVLPVADEDGTSTGAARAARTVDAAVAYEGMWRTFVETDAVVDALARATARGDGDGDGDGARKPARGHLTKRRAFDDALASLRRDHPASCFPEGGASLAAGASSTTARWNEFLRALRRRYGASASAWPFALLTKKIKRRRVYACAAAASFDAEGWTAAGWDVVLRGDARVERGGFGVRGGIGRGGSDASPVAAAKAAVAAASEAAAAAANEYENDDAARLAALEAMDARRVARAATWKVVETTETWEASFAAAAAGEEEEEEEDEEEEEEEEEEEATAAAAAIVAKNNVVAPAMTPAERRRRARLGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N514</accession>
    <name>C1N514_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="29">Flagellar outer dynein arm heavy chain beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="29" type="primary">ODA-DHCB</name>
        <name evidence="29" type="ORF">MICPUCDRAFT_70196</name>
    </gene>
    <organism evidence="30">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="29 30" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="29 30">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062890.1">
        <property type="nucleotide sequence ID" value="XM_003062844.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N514"/>
    <dbReference type="GeneID" id="9688530"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70196"/>
    <dbReference type="eggNOG" id="KOG3595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ICEHMAY"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000003">
        <property type="entry name" value="Dynein axonemal heavy chain 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000003">
        <property type="entry name" value="Dynein axonemal heavy chain 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000001">
        <property type="entry name" value="dynein heavy chain 17, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000002">
        <property type="entry name" value="Dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000009">
        <property type="entry name" value="Dynein heavy chain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000063">
        <property type="entry name" value="dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000002">
        <property type="entry name" value="Dynein heavy chain 9, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000049">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000007">
        <property type="entry name" value="Putative dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF8">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="11 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="9 29" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein heavy chain tail" evidence="19">
        <location>
            <begin position="204"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain linker" evidence="20">
        <location>
            <begin position="1296"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="21">
        <location>
            <begin position="1838"/>
            <end position="2166"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA 5 extension" evidence="25">
        <location>
            <begin position="2323"/>
            <end position="2442"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain 3 AAA+ lid" evidence="26">
        <location>
            <begin position="2658"/>
            <end position="2752"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="23">
        <location>
            <begin position="2802"/>
            <end position="3061"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="22">
        <location>
            <begin position="3074"/>
            <end position="3417"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="24">
        <location>
            <begin position="3443"/>
            <end position="3662"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain region D6 P-loop" evidence="18">
        <location>
            <begin position="3920"/>
            <end position="4039"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="27">
        <location>
            <begin position="4071"/>
            <end position="4216"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="28">
        <location>
            <begin position="4223"/>
            <end position="4515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="169"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="3069"/>
            <end position="3110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="3297"/>
            <end position="3352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF08385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF08393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF17852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF17857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="EEH52829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="4518" mass="511156" checksum="13607401F6727F98" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N524</accession>
    <name>C1N524_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52772</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063093.1">
        <property type="nucleotide sequence ID" value="XM_003063047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N524"/>
    <dbReference type="GeneID" id="9688533"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52772"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="330" mass="33567" checksum="5CD48DD3F4CC46F8" modified="2009-05-26" version="1">MSAPPPSSSSSRPRTSALERFRSKREAGGAVARSLGARFGEEENVEPSSSSADLARGSRGADHHHQRPYPSSGDAAPPRSSTTDRLAALKARRSAARPSSGRVGVASAAPSPAPSRNHDDDDDDLVDASPSSSSLPSAGKPPMTPWSGGSSGSYARRYAATPGGGPLSADRPGSRAHGLTPGQPASRLQNRFAGGGGGLLHRPGSARSNLSTPSSASSHSSRRAPKPPQEPAHVALLRGSVNPKIVFGAPAKSAARGGARSKGGGGGREGGKNYDDDDATEPTTMSVTAAPEGSFAAGGGVTVTMCRPKTARSISRWFPYDPARVVLADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N598</accession>
    <name>C1N598_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_21964</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SNAP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063133.1">
        <property type="nucleotide sequence ID" value="XM_003063087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N598"/>
    <dbReference type="STRING" id="564608.C1N598"/>
    <dbReference type="GeneID" id="9688371"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21964"/>
    <dbReference type="eggNOG" id="KOG1586">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WSVKEYL"/>
    <dbReference type="OrthoDB" id="9984275at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15832">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000049">
        <property type="entry name" value="Alpha-soluble NSF attachment protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF8">
        <property type="entry name" value="ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00448">
        <property type="entry name" value="NSFATTACHMNT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="293" mass="32471" checksum="84B6ACA6F82FD60A" modified="2009-05-26" version="1">MTDYAAKADEFMKKAQKKLKAGMFASMFGNKYEEASELLEKACNNYKLAKMWREAADAFALLADCHLKCDSKHEAAQAHVEAANANKKVDPAAAIASLRVAISHFTDMGRLSIAAKHLKDIAEQYEKDEKEDDACEAYMQAADLYGGEEVSTAANNCKLKVAELSASLERYPLAIEVFEEVAKASVSNNLLRFSVKGYLLNAGLCRLCSQEPVGVKNALERYEDLDPSFSTSREHTLLADLSSAAEEGDQEKFTAVLAEYDSMSRLDPWKTKLLLRAKKKIAKDVEEEEDDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5B2</accession>
    <name>C1N5B2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_52878</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063141.1">
        <property type="nucleotide sequence ID" value="XM_003063095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5B2"/>
    <dbReference type="GeneID" id="9688581"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52878"/>
    <dbReference type="eggNOG" id="ENOG502QV4U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GYRLDHN"/>
    <dbReference type="OrthoDB" id="2328924at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF15">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="392" mass="43973" checksum="E97C835E06CEFEFE" modified="2009-05-26" version="1">MCHDGAALNPFRGRKDAARMSDEDKFLFDTNGFVVVRGVFGADDLRRFHAAIDAHADRIHERKGQLRLTANRTPLSGDGVTGRKDLAGFLGWETPHREPFRDVLTHPRLLPYLHELVGPGYRLDHNPLLILQDPGSEGFEFHGGSTLDSGEWNHPLGYQFNHGKMRCNLLAFAVHLTDVKEGEGGFCVIRGSHKSNYACPAAIKRYERAVEHAHQPAIDAGDVVVFTEATTHGTLPWRGASQRRNVIYRFSPATNAYGRGCALASVARIFHPIPVSNVDRDVRSTDPRRRSLRASQVRRERVAERVSGGHDGRAGAFDTNVNFTHRSLSTFDRVSFQLTDELLAQRSVMNPPYHPRLNRTVVAEDGVRAIEAAPREKHKVDFDRAVFKQDYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5E4</accession>
    <name>C1N5E4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53304</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063345.1">
        <property type="nucleotide sequence ID" value="XM_003063299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5E4"/>
    <dbReference type="GeneID" id="9688785"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53304"/>
    <dbReference type="OrthoDB" id="568421at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910759" evidence="1">
        <location>
            <begin position="26"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="274" mass="29011" checksum="56D36C36D8AA95EC" modified="2009-05-26" version="1">MSPRVVLRRALACLVVLAAAPTARASSDAAADADAWRLDFSEQGPHDVSVARVAILRAPPAIPTDGGVPTTGGEPGEVAVYFPTSPTRTARERGGEKLACVLFAHPTHGYRFETWASNNAKLLTHLASRGVVVVTPTRVGELSGAGADAPIAGGLLPGAQFVRTLFPRYQRFLLHALSQVMRRSETRDDGFFAPLRGAIDPFRAATMGFSVGGALAIYVAEEAQRAMPGRVKAVVALAPTVGDIEYGEEQFALRAHRLTTPLLMTAGRNDGAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5L5</accession>
    <name>C1N5L5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_63700</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063180.1">
        <property type="nucleotide sequence ID" value="XM_003063134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5L5"/>
    <dbReference type="GeneID" id="9688620"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63700"/>
    <dbReference type="eggNOG" id="KOG1981">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NEAIMHE"/>
    <dbReference type="OrthoDB" id="514638at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF11">
        <property type="entry name" value="LD23868P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="626"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="872" mass="91304" checksum="523D7E93219CFB70" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5Y8</accession>
    <name>C1N5Y8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_22338</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063445.1">
        <property type="nucleotide sequence ID" value="XM_003063399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5Y8"/>
    <dbReference type="STRING" id="564608.C1N5Y8"/>
    <dbReference type="GeneID" id="9688681"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22338"/>
    <dbReference type="OMA" id="AESWWNQ"/>
    <dbReference type="OrthoDB" id="89176at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="entry name" value="Chorismate lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002800">
        <property type="entry name" value="Rv2949c-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01947">
        <property type="entry name" value="Rv2949c-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="Chorismate lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="192" mass="21499" checksum="CC7CFF20E664D1FD" modified="2009-05-26" version="1">MGRGGALGPLLSPPWRVMLLSDGSVTRHLQLLTDGKVSAEAETPVPVRPYHTGSHTTARLLQREVDLCRGADGVPLVYASSWWTIDAAKRFNILQARIHPPADGGASERAVWMNLSDKRTELFREVRRMYLGDSVALENAWGVRGPFWARHYIFWAGNRPLCVIYEVFSPTLEAYLGAFYTKVFHPSLGFNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6D7</accession>
    <name>C1N6D7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63933</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063516.1">
        <property type="nucleotide sequence ID" value="XM_003063470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6D7"/>
    <dbReference type="STRING" id="564608.C1N6D7"/>
    <dbReference type="GeneID" id="9688955"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63933"/>
    <dbReference type="eggNOG" id="KOG1408">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6154712at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052779">
        <property type="entry name" value="WDR62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589:SF1">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="792" mass="80583" checksum="B2EEACC8F4F6CB55" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6H0</accession>
    <name>C1N6H0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53284</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063336.1">
        <property type="nucleotide sequence ID" value="XM_003063290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6H0"/>
    <dbReference type="STRING" id="564608.C1N6H0"/>
    <dbReference type="GeneID" id="9688971"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53284"/>
    <dbReference type="eggNOG" id="KOG2914">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NADCHIC"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044999">
        <property type="entry name" value="CbbY-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42896:SF4">
        <property type="entry name" value="OS08G0485900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42896">
        <property type="entry name" value="XYLULOSE-1,5-BISPHOSPHATE (XUBP) PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="318" mass="33976" checksum="E98B4AD086C11EDD" modified="2009-05-26" version="1">MPAAAAAAAAASASAASRAAPLSTPRASRRAAPRAAARCAASNTTNARFALLFDCDGVIVETEELHRRAYNASFEHYELTIDGVPLSWSVEYYDVLANTWHFGKNGWPKSPRFFSGALPACEDDENALVDALQDKKTEFYKKIVEETAEARPGVLRLMDEAIADPSIAVGICSAATKAGFEKVVNSVVGPERLSKLDVIMAGDDVTRKKPDPLIYNLAREKVGLPASKCVVVEDSLVGLRAAVGADMPARSVHWSPYDRVRAAHACLITPCPSSDVPDFKKEGAMAVCDDRKGLEGPPRVTVKGLFPEGAESPSFEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6P1</accession>
    <name>C1N6P1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Chloroplast envelope protein translocase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">TOC86</name>
        <name evidence="19" type="ORF">MICPUCDRAFT_48918</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Plastid</location>
            <location evidence="15">Chloroplast outer membrane</location>
            <topology evidence="15">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. TOC159 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063586.1">
        <property type="nucleotide sequence ID" value="XM_003063540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6P1"/>
    <dbReference type="STRING" id="564608.C1N6P1"/>
    <dbReference type="GeneID" id="9689208"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48918"/>
    <dbReference type="eggNOG" id="ENOG502QR60">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TKLENRW"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009707">
        <property type="term" value="C:chloroplast outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045036">
        <property type="term" value="P:protein targeting to chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000413">
        <property type="entry name" value="Translocase of chloroplast 120, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006703">
        <property type="entry name" value="G_AIG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045058">
        <property type="entry name" value="GIMA/IAN/Toc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024283">
        <property type="entry name" value="TOC159_MAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903">
        <property type="entry name" value="GTPASE, IMAP FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903:SF135">
        <property type="entry name" value="TRANSLOCASE OF CHLOROPLAST 120, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04548">
        <property type="entry name" value="AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11886">
        <property type="entry name" value="TOC159_MAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51720">
        <property type="entry name" value="G_AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1002">Plastid outer membrane</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="19" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="19" id="KW-0946">Virion</keyword>
    <feature type="domain" description="AIG1-type G" evidence="18">
        <location>
            <begin position="262"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="108"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH51959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="827" mass="87462" checksum="5C71009A9C9661C5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N718</accession>
    <name>C1N718_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42999</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063653.1">
        <property type="nucleotide sequence ID" value="XM_003063607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N718"/>
    <dbReference type="GeneID" id="9689094"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42999"/>
    <dbReference type="eggNOG" id="ENOG502ST2Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WVPIFEQ"/>
    <dbReference type="OrthoDB" id="10577008at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="436" mass="50091" checksum="DD0216F2D5F185BF" modified="2009-05-26" version="1">MALDDPNTTKSSIETMKKALADTLAKRMLAKFIAPNAPAPDVVTITAIVREEVDGFMNNTGSVKESEIAALERRIKDRITGGKVAGRRFGAPVVDEWAEISKWQAKENDRVQAEKLASYKASQRKMKEELDAQVAEKARKKLLEKEEVVADKVDVTRRLEEWKLDELEKIAKRTAAVDKLKTDRRAQLEDKAARKAAMEEEKRQEEADLRRALAADYRRKQAEEAAAKRKIAAEIEKLKKSNEETLALRAKQAADDEALDLKYQEMYAEKLRKQEEAYHANLLKMKEKQKSQEAFGNAIGPYKRYMPDEIIEKNAANYDRLAAERDARDAKHQVDLNAAVKKELAEQVKAKQERLDRERDEEARRYARFARVVDTLESAERESRREGFERAVRHKEELEAQMRDNMVRKKVFPMTATEKELNTALLQRVKAEQGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N786</accession>
    <name>C1N786_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_53593</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063854.1">
        <property type="nucleotide sequence ID" value="XM_003063808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N786"/>
    <dbReference type="GeneID" id="9689135"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53593"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="442"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="365"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="709"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="101"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="365"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="722"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="743"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="822" mass="90068" checksum="7D7D1288AA2BD375" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7A1</accession>
    <name>C1N7A1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_53611</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DExH box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063861.1">
        <property type="nucleotide sequence ID" value="XM_003063815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7A1"/>
    <dbReference type="STRING" id="564608.C1N7A1"/>
    <dbReference type="GeneID" id="9689143"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53611"/>
    <dbReference type="eggNOG" id="KOG0920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IVRVRHP"/>
    <dbReference type="OrthoDB" id="5600252at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059023">
        <property type="entry name" value="RNA_hel_CTD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF145">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26026">
        <property type="entry name" value="RNA_hel_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="48"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="437"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="452"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00060772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="658" mass="71420" checksum="9F4F763F9A4641DC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7R5</accession>
    <name>C1N7R5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_30105</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Whirly family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063954.1">
        <property type="nucleotide sequence ID" value="XM_003063908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7R5"/>
    <dbReference type="GeneID" id="9689395"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30105"/>
    <dbReference type="eggNOG" id="ENOG502QRRY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="511009at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.31.10">
        <property type="entry name" value="Transcriptional Coactivator Pc4, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009044">
        <property type="entry name" value="ssDNA-bd_transcriptional_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013742">
        <property type="entry name" value="Whirly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31745">
        <property type="entry name" value="SINGLE-STRANDED DNA-BINDING PROTEIN WHY2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31745:SF1">
        <property type="entry name" value="SINGLE-STRANDED DNA-BINDING PROTEIN WHY2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08536">
        <property type="entry name" value="Whirly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54447">
        <property type="entry name" value="ssDNA-binding transcriptional regulator domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="302" mass="32763" checksum="5C4CDAC563102BF3" modified="2009-05-26" version="1">MSLARAFRTRSATSLARAAAHRASSSSFHSQQQQRQQQQRQPRPSGGGAPPTPQTPPQGAASPGFAAKPFQGVPNFSSASANAPAYQQRFEQRAQQQQQQQYGGGGGGGQQQQQQQQRPPPQQKQRYAAERGGDAGAPKVYCNFAIHKSKTAVQMSAIKPTFELLPNGSKQKKRDGAMFLEFAPVAAGAGQKQYDWSRKQSISLSPLEFMELSEALAANRGVNFFHDPWMGTSRQGETTKSLKAEPMPDGSGGIFLNLTVASGGGRVEKLNIAVSFQEFAVFRELARYLVPRLTGFSEQFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N881</accession>
    <name>C1N881_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53984</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064223.1">
        <property type="nucleotide sequence ID" value="XM_003064177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N881"/>
    <dbReference type="GeneID" id="9689477"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53984"/>
    <dbReference type="OMA" id="FFWIAKE"/>
    <dbReference type="OrthoDB" id="10632037at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="383" mass="39348" checksum="3E8E2A7A62CC8275" modified="2009-05-26" version="1">MSAAAATRGAPPPPSRARPRARRRRVLARAPRASSATTADADATRDVDDDDDEMEIRRMRAWCDATSRGVDASPSDVAAFNALVDAVVARTTTSASTSTSTSSLANTRWRLLGCAQRTLPSPGAWLASPFFWIAKEAQQESYRLATSAPDLFPPFKLAARLSAGMDAPKTGEMWIDAFGKREVRAGFPFGVIESFLNGFAVAFRAGDATLEFGDDDGDDGGGGDGETTTTTTMMTSRVRVDFGDGAVVGDLVTECVVGLAEETGGGDDATATTRRKMASLVSTRFENTGVVALDGVAVPSGAIMKTLMSPSPSLRERTTGARGHPGVPYAAAIVVVGGGTAGGGTAGGGTAGGGGEAEAEAYLVATAGSCEATSTALLYERVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8C5</accession>
    <name>C1N8C5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43296</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064058.1">
        <property type="nucleotide sequence ID" value="XM_003064012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8C5"/>
    <dbReference type="GeneID" id="9689686"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43296"/>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317">
        <property type="entry name" value="BLR8090 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317:SF1">
        <property type="entry name" value="ZINC-RIBBON DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="2">
        <location>
            <begin position="32"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="2">
        <location>
            <begin position="100"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="168" mass="19459" checksum="1559A3467446B328" modified="2009-05-26" version="1">MRTGPKGKPFLEWCAENGKRGERLANEFREELPTELTKASNYKAKWKCLKCKHVWRAEMNSRTKSERPKGCPKCAHNAPASKTKNFLAWCEKKGELGKKLSREYVDKDKPPTAVTYASHYRALWKCGRCSHEWRTRVADRTKSVRPTGCPECNPPGTNRYTKKRERVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9L8</accession>
    <name>C1N9L8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54533</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH50967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064633.1">
        <property type="nucleotide sequence ID" value="XM_003064587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9L8"/>
    <dbReference type="GeneID" id="9690311"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54533"/>
    <dbReference type="OrthoDB" id="502528at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="638"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="674"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="750"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="827"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="846"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="870"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1064"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH50967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1252" mass="137792" checksum="1402976AFB098171" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9R6</accession>
    <name>C1N9R6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_45095</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064781.1">
        <property type="nucleotide sequence ID" value="XM_003064735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9R6"/>
    <dbReference type="GeneID" id="9690102"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45095"/>
    <dbReference type="eggNOG" id="KOG0061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PWLAWIK"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF41">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH51115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="556" mass="59084" checksum="CAE194180DE29F94" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA39</accession>
    <name>C1NA39_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54750</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064842.1">
        <property type="nucleotide sequence ID" value="XM_003064796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA39"/>
    <dbReference type="GeneID" id="9690164"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54750"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="229" mass="24632" checksum="B82B59F5AC8BB1EC" modified="2009-05-26" version="1">MSDADPRRLTFEEATTRRGDGADEDVPEWLRLKRAKGAALRERLPKRSSGSTTSTPPVAARRASPPSWTPSPGSSGGRPRSSSSRVVELGVLDRFRLTATLVEEDEGGGEEEEEEDGDVDSDSASSSSGGLEREDLRMRVPEVFDADAATLAGGVPARPSRSPRKVEPMDGSTSSSRPPPPPTALTSLEFPETDRRAAAFQARCDEVLRAVDEEIERRRGMTSGVARIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAE8</accession>
    <name>C1NAE8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54872</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064951.1">
        <property type="nucleotide sequence ID" value="XM_003064905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAE8"/>
    <dbReference type="GeneID" id="9690333"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54872"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="235" mass="26349" checksum="F0F89155028F26FF" modified="2009-05-26" version="1">MPSFRLTTAREPTTPPESYPLVENLTPEKSALVERILAKSPDFATRKRKERDVPFRVTDAARVTLERNNCPRAAIDACASKEDVEKLFDDYVYAITGPQAAFLKDFGIDVSEVKTRDVASALIRKMKYKLPATEKQMREHARIYRRDNITGETPVGLTEAAASSLIHDLNNMLPITGLQRDSLMFNGLPDHEIPESFNAASAMLARFERKTPADTQQRRVAQAIRRSEGAISLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRB1</accession>
    <name>C1KRB1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="9">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MicpuC_chl3</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="11"/>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="9"/>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRB1"/>
    <dbReference type="STRING" id="564608.C1KRB1"/>
    <dbReference type="OMA" id="WGERTLP"/>
    <dbReference type="OrthoDB" id="1862828at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF54">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4 11" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="10">
        <location>
            <begin position="358"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACO50743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="782" mass="89276" checksum="11FB8C5AFDCB6684" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGK1</accession>
    <name>C1MGK1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_49844</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055335.1">
        <property type="nucleotide sequence ID" value="XM_003055289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGK1"/>
    <dbReference type="STRING" id="564608.C1MGK1"/>
    <dbReference type="GeneID" id="9680559"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49844"/>
    <dbReference type="eggNOG" id="KOG3987">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PYMHYVE"/>
    <dbReference type="OrthoDB" id="199041at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106370">
        <property type="term" value="F:protein-L-histidine N-pros-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007884">
        <property type="entry name" value="METL9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12890">
        <property type="entry name" value="DREV PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12890:SF0">
        <property type="entry name" value="PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05219">
        <property type="entry name" value="DREV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="336" mass="35963" checksum="85FA8F8B52FEFEC6" modified="2009-05-26" version="1">MELVRSWLGVPADGAVETLSVMCAHCNAKLTPTQLDYDCVRARLPDELNRAFAPLERDDATNAFLMRSSRRPYVVNWGASVACSYLRKRMSLTDANAILGRGKMHVLSRAHVEDLLGRKRASNGGGGGDAGCGGGGGGGGVLLDVGAGEGEVTEKLRDGGCFDAVVATEVSPPMVKRLKDKRFDCVIGAADVSGVFDAARNENVKRLSPDGFDAIALLNVLDRCDTPFTLLSQLRGMLRPGVGRLLLAVVIPFRPFVEDGNSNRPPRERLPLPSDGGWEDGVSKLWSLVLKPAGFKIERLARVPYISEGDQKHGAYVLDDAIFVLSPASGDDDDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGY0</accession>
    <name>C1MGY0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartyl aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_43781</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.</text>
            <dbReference type="EC" id="3.4.11.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M18 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.21" evidence="4"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055398.1">
        <property type="nucleotide sequence ID" value="XM_003055352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGY0"/>
    <dbReference type="STRING" id="564608.C1MGY0"/>
    <dbReference type="MEROPS" id="M18.A01"/>
    <dbReference type="GeneID" id="9681026"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43781"/>
    <dbReference type="eggNOG" id="KOG2596">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LLDTHYY"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.250.10:FF:000001">
        <property type="entry name" value="Aspartyl aminopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002759">
        <property type="entry name" value="PRK02813.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF3">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH60650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="476" mass="51432" checksum="4B2AD045FA8DF58D" modified="2009-05-26" version="1">MASSVPSEIPAIATELVDYLNASWTSFHATSESSRMLAAAGFERLSEKESWDLKPGGKYFFTRNMSSIVAFAVGEKYAPGNGFNIIGAHTDSPCPKLKPVSAIKKGGFLSVGVQTYGGGLWHTWFDRDLSVGGKVLLRRASAKGRLSHELVRVDRPIIRIPTLAIHLDRNVNTEGFKPNTETQFAPVLATAIRGELEQETAKKKKKKKPAHHPLLLAVLAEELNCDPDEIVDFELEVCDTQPSVIGGAAREFIYSGRLDNLASSFCALKALLHAGGGDGDLENETGVRMIALFDNEEVGSDSTAGAGGTMVADTVNRTARALCGGADAAEGLVERTLRRSFLVSADMAHALHPNYMDKHESNHSPKMHAGVVVKHNANQRYATTATTATLFRECAAKEGIPTQDFVVRNDMGCGSTIGPILSTNLGVRTVDVGVPQLSMHSVREMCGTEDIDVCFRHFRAFFDHFAEIDANADDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH28</accession>
    <name>C1MH28_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50029</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054880.1">
        <property type="nucleotide sequence ID" value="XM_003054834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH28"/>
    <dbReference type="STRING" id="564608.C1MH28"/>
    <dbReference type="GeneID" id="9680838"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50029"/>
    <dbReference type="eggNOG" id="KOG0910">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42985at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43601">
        <property type="entry name" value="THIOREDOXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43601:SF3">
        <property type="entry name" value="THIOREDOXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="45"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="210" mass="22099" checksum="D90A7DB6285872D3" modified="2009-05-26" version="1">MPLASSLTSARALRGDAAAARASSRRRPSARDASSSSLLPSARRIARGRSSPAVRASGSPFDKLEIWDAERAECALAEGGTAVVSFGTTWCGPCAVLKPELEQLARAMDDVRAVADVVVAKLDAEEAPALASAHAVGAYPTTLWLREGAEVHRLEGSLPASALVQLTAMHLLDAEAEEFLRAEQPKWFAPTPLEPMEMASASRAAPGMLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH72</accession>
    <name>C1MH72_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_30731</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055443.1">
        <property type="nucleotide sequence ID" value="XM_003055397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH72"/>
    <dbReference type="STRING" id="564608.C1MH72"/>
    <dbReference type="GeneID" id="9680854"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30731"/>
    <dbReference type="eggNOG" id="KOG4232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF19">
        <property type="entry name" value="DELTA(5) FATTY ACID DESATURASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="12"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="427" mass="47569" checksum="C41E21760F5043FC" modified="2009-05-26" version="1">MKRVDTAKDVGAKTFTARELLATATSGKDDRLLIAIDGRVHDVTGWTKHHPGGATLLKQHAGHDASDVFAAFHAPEVYRKLRAFDVGADLKKQNRARELAAFRDLRERVRKEGLFEPSYAHMFGTFLRLFVIGAFAAVFSFAPNSTPRGRILGAALLGLFWQQSLLIAHDACHRVMTTNTKVDKWIGSVFGTLIGGVGAAWWNMEHCEHHCVTQVVGGDPSAGAAPVLCLELQTKGLPKIGRALVKLQALYYVPVCIFIGRFNLHLISILKAPSKGKALDVALMTGYMSYVYGLTRLVPESERWRWFMIANAVCGVLHLILNMNHYPMPMLSFPESQALGWLRFQCVTTMNIASSSLTGWYYGGLEWQIEHHLFPTMPRHNLRKVSHRVKELCLANGVPYHVAEGGFWDANWSVMKTLHDVARGLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH85</accession>
    <name>C1MH85_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_2718</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054910.1">
        <property type="nucleotide sequence ID" value="XM_003054864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH85"/>
    <dbReference type="STRING" id="564608.C1MH85"/>
    <dbReference type="GeneID" id="9680788"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2718"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FTKGEKW"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46699:SF5">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46699">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE STN8, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="16"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="362" mass="40114" checksum="5F6CEC19C2A25C7B" modified="2009-05-26" version="1" fragment="single">LALRVHAGAKYKRTDVEVERQIGEGSFGIVYQGKIAKVKKDVVLKRPKLTVEGAAELQEVEAWMNDRVTRDARGSCADFLGSFRVTPDESYLHSSSEGVVAKEGLWLVWRYEGDRTLAQYMAQPDYPAGIAKVMLGKEGNNLRGDASVELEVTQATMRQIFKNLRVVHTAGLIHRDIKPHNLVLTNEDRFKLIDLGACACFRTGMNFAPDETIMDPKYAPPEEFLIPSDDAPDIRKLFGPVALAAGSAAWVQHKPDRFDMYSAGVVMMQLALPSLRTNNGLMTFNRGLKRVGYDLFLWRDANKSQLKRSQTAVLDAGNGAGWDLARELLRPRAYDEDAATAASAAAEKQRAKKGEDEEGTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHA2</accession>
    <name>C1MHA2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_61269</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055454.1">
        <property type="nucleotide sequence ID" value="XM_003055408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHA2"/>
    <dbReference type="GeneID" id="9680886"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61269"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="67"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="191" mass="20094" checksum="9F323A48B5CD4BCB" modified="2009-05-26" version="1">METLDVDVGVVMCPSADSEPREKSAHAAAARGIRTSSSAPPPTPPPPPTRGAPTRVRGGDDGHATCGWVFHRDDVFARPLLARLLTALANEPAVKRVKGVLRLGSEWVAPAVAVGGDGRTRVALEPAAYRRDSRIEIIATNVAARGEIIKGEGEDDRVVDGDVVDRAGEAARANDWDAVESAIVATLKPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHI0</accession>
    <name>C1MHI0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_50205</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054956.1">
        <property type="nucleotide sequence ID" value="XM_003054910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHI0"/>
    <dbReference type="GeneID" id="9680679"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50205"/>
    <dbReference type="OMA" id="FECHAIS"/>
    <dbReference type="OrthoDB" id="10588274at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="473" mass="49444" checksum="2F35215EE8663576" modified="2009-05-26" version="1">MDGRANHGLDPWDFKHSGKIATFAEDDPFECHAISVSNDGTRLAAAGASPRSPAAAVARIFSVRARESSLEATITAEGAIGATSVALSRDAVFLGCADGSLWSFDFPTGVLTRHEPHPALAALPRRRRPIRNPFASGDREPRSIRRLIFVGDGHLVGSVSNHGVLPVWGRARERDAAPGELPDASPSAFHDDPSFSKEDGAFIHLASHGDFLYSTSIDAKGLRAWSCDSIGGRLWESERLAAGRGVHLAGIAVLPRREVPPLIATCVSSLIRGTSYAEPDTTLKIALVDGDSGRELRRYAVEGVGATNRFIDCSSLTGGGGGTLLFLAHKDGSIWIHAARNGAQVAALHGHATWSGTSGHHRVLPTCVAAGSDGEFFYSATTDGKAVHRWTVGPPRVWSRDTHARFPSAFKATVRALVTAVHAREARGGGGGGGGASVLAAAAGIDGEVSEDGSGAPALWGKGFAELCAIDLG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-10-19" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIE8</accession>
    <name>GATB1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName>Glutamyl-tRNA(Gln) amidotransferase subunit B-1, chloroplastic/mitochondrial</fullName>
            <shortName evidence="1">Glu-AdT subunit B-1</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">GATB-1</name>
        <name type="ORF">MICPUCDRAFT_50541</name>
    </gene>
    <organism>
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">This protein may be expected to contain an N-terminal transit peptide but none has been predicted.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055655.1">
        <property type="nucleotide sequence ID" value="XM_003055609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIE8"/>
    <dbReference type="SMR" id="C1MIE8"/>
    <dbReference type="STRING" id="564608.C1MIE8"/>
    <dbReference type="GeneID" id="9680990"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50541"/>
    <dbReference type="eggNOG" id="KOG2438">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ARKWWMG"/>
    <dbReference type="OrthoDB" id="1722066at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.410:FF:000001">
        <property type="entry name" value="Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="GatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004012">
        <property type="entry name" value="PRK05477.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004014">
        <property type="entry name" value="PRK05477.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF0">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0150">Chloroplast</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0934">Plastid</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000413225" description="Glutamyl-tRNA(Gln) amidotransferase subunit B-1, chloroplastic/mitochondrial">
        <location>
            <begin position="1"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03147"/>
        </source>
    </evidence>
    <sequence length="545" mass="58917" checksum="8F8864E4D48D22EE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIF6</accession>
    <name>C1MIF6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_24405</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055121.1">
        <property type="nucleotide sequence ID" value="XM_003055075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIF6"/>
    <dbReference type="STRING" id="564608.C1MIF6"/>
    <dbReference type="GeneID" id="9680930"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_24405"/>
    <dbReference type="eggNOG" id="KOG1371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YGTAGMK"/>
    <dbReference type="OrthoDB" id="494308at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05255">
        <property type="entry name" value="SQD1_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="2">
        <location>
            <begin position="93"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="489" mass="53694" checksum="2EBC80EDACF319C4" modified="2009-05-26" version="1">MSAFTMAASAVGVKVTTTAKRASAKRATAKASSSAFSARKASLNGVSLAAFAAPSVAASKSSQIRALRSAVFAAAKADRSKADDPDAGKGQRVMIIGGDGYCGWATALHLSNRGYEVCIVDNLCRRGMDDSLGFNSLTPIRGIHERVRKWKEVSGKDIELFIGDVCDYEFLSATFKKFEPTAAVHFGEQRSAPYSMMDRTKAVFTQTNNVMGNINLMYAIKEFAPDCHLIKLGTMGEYGTPNIDIEEGYLTVEHNGRTDTLPYPKQGNSFYHLSKCHDSTNMIFCTKAWQMRTTDLNQGVVYGVATEETMMDPALINRLDYDAVFGTALNRFCIQAAVGHPMTVYGKGGQTRGFLDIRDTVRCIQIACDNPADKGEMRIYNQFTEQFSVNELAALITEAGKKIGLDPQVINVPNPRTEMEEHYYNAKNSKLQDLGLEPHLMSDALMDSLLKIIIEYKDRVDKSLILPGVNWTESASVGQQLEKAEKVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIQ0</accession>
    <name>C1MIQ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50652</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055169.1">
        <property type="nucleotide sequence ID" value="XM_003055123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIQ0"/>
    <dbReference type="GeneID" id="9680727"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50652"/>
    <dbReference type="eggNOG" id="ENOG502S9A5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43521at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="365" mass="39357" checksum="F989FBA057D79B45" modified="2009-05-26" version="1">MAAAMATTSATALVASRRAATDASALSSRDALRAAPLAPSRRRPGGAAAIFFRSGGRASSSNASSATTASASNAAGGDPWWKPPATPRAAGATEPRAGAGGLSRSAPRATGGGVVSGASERSGAAERRRAPPLAAPGAPSRVADYTRSGGSLQITRELLQRARRARADRSRRTRQEESVFSRSGGFVYARDFFSPDDFRVVREACETLRASLATERRACAKQRLGVMIPREHVVHRAFMNQTVADRISRLVGKDLQPADVPVEFRVYPPGSAMDWHQDVALYTEPQYELVFTLDNTSDSQTQWQDGEGARRGGWTEPNSVIVVRAESVIHRVTPITKGERSIVKFAFTSTLEKTREYYENLQTYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIT2</accession>
    <name>C1MIT2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_50685</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Protein transport. Probably involved in vesicular traffic.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055718.1">
        <property type="nucleotide sequence ID" value="XM_003055672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIT2"/>
    <dbReference type="STRING" id="564608.C1MIT2"/>
    <dbReference type="GeneID" id="9680740"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50685"/>
    <dbReference type="eggNOG" id="KOG0098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CEAIFIA"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01866">
        <property type="entry name" value="Rab2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000263">
        <property type="entry name" value="Ras-related protein RABB1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="219" mass="23577" checksum="7F5AB243F4E7C0D4" modified="2009-05-26" version="1">MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQHVHDLTIGVEFGSRLVAIGEKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFEHLTSWLEDARQHANPNMTVTLVGNKSDAEASRVVSTEEGEAFAREHGLAFLETSAQTSEGVEEVFTSTAAAICAKIDDGLDVNNESNGIKPGYGGARGGGIRSGGGGVVDVGVQPARRSEGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIY8</accession>
    <name>C1MIY8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_61760</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055219.1">
        <property type="nucleotide sequence ID" value="XM_003055173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIY8"/>
    <dbReference type="GeneID" id="9680975"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61760"/>
    <dbReference type="OMA" id="CASTRFR"/>
    <dbReference type="OrthoDB" id="10626342at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="222"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="547" mass="59509" checksum="57A4642957AC7432" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ80</accession>
    <name>C1MJ80_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_46434</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055787.1">
        <property type="nucleotide sequence ID" value="XM_003055741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ80"/>
    <dbReference type="GeneID" id="9680538"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46434"/>
    <dbReference type="OMA" id="WRAIVYV"/>
    <dbReference type="OrthoDB" id="10494877at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH61039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="313" mass="33206" checksum="CB947B0641F6B2CB" modified="2009-05-26" version="1">MAPGGDHVANARDASIRGEAPDDGVFLDDRARAVLGGRKRARETSGHPTNEDDDTPTDSPAPTPGVIPTPEQGTPMISVDGVKKKRNSKPKRIQFGEPPPGVINIAIDPPNGRYNKNGVCHHKASGKWRAIVYVNKKQVNLGYFTTKEESEETVRRAREFGLPPGFVNCRAHAQPKRSAINGVNWDKHCKRWLARVYEPTKDGKKGKEHKVGYYDDEEEAGRAIIARRKELGLPEKSTRKKREKKTGTGTVAAAAAAGAAASLATIGVGGGGGGSGAGAVEASVNFDGLVDLGAVEAMTVGGALGVPPPRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJL4</accession>
    <name>C1MJL4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_55006</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055840.1">
        <property type="nucleotide sequence ID" value="XM_003055794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJL4"/>
    <dbReference type="STRING" id="564608.C1MJL4"/>
    <dbReference type="GeneID" id="9681410"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55006"/>
    <dbReference type="eggNOG" id="KOG0054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="60"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="479" mass="52894" checksum="F94C068F69B1FAD6" modified="2009-05-26" version="1">MDNDPQYLEHGTNMATELETKMNAVERVKEYVDLPEESEHDTDPVIAAALPHSWPAKGLLEVSDLRMRYRPSLPLVLKDVTFVAAAGEKLGICGRTGSGKSSLFLALFRIIEPAGGVIKIDGVDVSTLGLHQLRSKMAMIPQGAFSFFLSHLLFLKDFSRRISLPTPRFQYPSSTPFNSASDAFQLHPDVASYGQTPSSDPFMFAGTIRNNLDPFDEHDDAAVWSALEQVGLKHMAEDAAKKLDMEVVDNGGNFSLGQARSITTPDFLSRRASLSAHPTVSTPDTPRRLSTPSDAPSQLQRQLLCMGRALLRNSRVLMMDEATASVDMDSDALIQKTVREAFAACTTLTIAHRLNTVRLLPIRPRWRGERRSLRTFAGVSLSPPLAFNPRPRRLSTPSDAFQRAQVMDSDKVAFLDDGELVEFGEPEELLKNPKGKFTALVNRTGEKQSKFLRTMSTRAHESRLARIASESEIADAVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJU4</accession>
    <name>C1MJU4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_11783</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055880.1">
        <property type="nucleotide sequence ID" value="XM_003055834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJU4"/>
    <dbReference type="GeneID" id="9681437"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11783"/>
    <dbReference type="OrthoDB" id="206985at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="71" mass="7712" checksum="62145D0FD008E4E2" modified="2009-05-26" version="1" fragment="single">GIDFLGIGYDLLNGNPHGDVDTPIDPGFRAPVVSLTYCEGDDTQCATRDLRDLQPIEGWDLPEFACTQAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJX0</accession>
    <name>C1MJX0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55133</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056284.1">
        <property type="nucleotide sequence ID" value="XM_003056238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJX0"/>
    <dbReference type="GeneID" id="9681899"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55133"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="68" mass="7289" checksum="D65AE55BE827C768" modified="2009-05-26" version="1">MSELVGSRALADGDVTDSARSSASYEFATRIIESNLVHLCDPGVEVTNKPHERCTVVRGASCPKARLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKC9</accession>
    <name>C1MKC9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_31393</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056364.1">
        <property type="nucleotide sequence ID" value="XM_003056318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKC9"/>
    <dbReference type="STRING" id="564608.C1MKC9"/>
    <dbReference type="GeneID" id="9681488"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31393"/>
    <dbReference type="eggNOG" id="KOG0616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DRFPHDQ"/>
    <dbReference type="OrthoDB" id="497971at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000024">
        <property type="entry name" value="Probable serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="25"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH59740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="352" mass="39718" checksum="CE9B727D5F97AFDA" modified="2009-05-26" version="1">MSSEEYQALLSAETAEAAKDPFEGYTFVKQLGVGLTGSVYKCWKPNLSKAGVQDKEKPYVAVAVKIMDKAQILDINETEHVTRESSIMKAVCRHPFIITMSESFQTPSALCIVMEYAAVKDLFFMIHELGALSLFQTRAYFVQVVLALDHVHHKGFVYRDLKPENLLVRDDGYLRLTDFGFAKALKPGERAYTVCGTPDYLSPEALRHHGCNRAADFWAVGILLFEMMAGYPPFYGQTHSDLYRRITEGKHRTFPNTMSPHAQDLIRQLLRQEEGERIGMGAGGIQAIRSHPFFKGFSWSAVLEQRVDMTLPSKIEPDADLGPEDITEPCEVPCLTELYNLTDEEQKLFEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKY9</accession>
    <name>C1MKY9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64711</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056468.1">
        <property type="nucleotide sequence ID" value="XM_003056422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKY9"/>
    <dbReference type="STRING" id="564608.C1MKY9"/>
    <dbReference type="GeneID" id="9681379"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64711"/>
    <dbReference type="OrthoDB" id="2017782at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051966">
        <property type="entry name" value="RPAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423:SF1">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="223" mass="25983" checksum="16369F8443742939" modified="2009-05-26" version="1">MIFIYYFHYAYCTRVLFYTVRVALQRCRLVIPSYESTSVQRSNVVLPEGHQARHAVMTVEVQHRVRETALDFDVFLEDLKQWTREVQQKDKALRCLEFALDKKEECRTSAPASAKYIPVKVRARARLLLDNAEGEFENRDSSKHGTFLEELLKIGNGCFRKREYDSAILHYSRYIQTHRNSSAAFANRAMCHMNNKCWALAEVDCTYALEVDPNNVKVGQIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML65</accession>
    <name>C1ML65_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_55592</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056120.1">
        <property type="nucleotide sequence ID" value="XM_003056074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML65"/>
    <dbReference type="STRING" id="564608.C1ML65"/>
    <dbReference type="GeneID" id="9681763"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55592"/>
    <dbReference type="eggNOG" id="ENOG502QW1B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AFERIVW"/>
    <dbReference type="OrthoDB" id="297739at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF83">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="599"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="642"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="698"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="758"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="805"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="838"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="885"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="4">
        <location>
            <begin position="301"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="3">
        <location>
            <begin position="596"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="970" mass="108766" checksum="BF474C2FD60FBED9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML70</accession>
    <name>C1ML70_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_9314</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056123.1">
        <property type="nucleotide sequence ID" value="XM_003056077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML70"/>
    <dbReference type="STRING" id="564608.C1ML70"/>
    <dbReference type="GeneID" id="9681401"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9314"/>
    <dbReference type="eggNOG" id="KOG1590">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FLQHFWG"/>
    <dbReference type="OrthoDB" id="1697690at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="94" mass="10410" checksum="7E4548ECA431C77F" modified="2009-05-26" version="1" fragment="single">MHNSAFARWVASPTGPKTTHFWGPVANWGFVLAGLNDTTKSPELVSAPMTGALVVYSGLFMRFAWRVQPRNAILFACHACNASVQGYNLQRWAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML81</accession>
    <name>C1ML81_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Large ribosomal subunit protein uL2m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_31769</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056128.1">
        <property type="nucleotide sequence ID" value="XM_003056082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML81"/>
    <dbReference type="STRING" id="564608.C1ML81"/>
    <dbReference type="GeneID" id="9682009"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31769"/>
    <dbReference type="eggNOG" id="KOG0438">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="563959at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000001">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_uL2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_uL2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_uL2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF72">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="11">
        <location>
            <begin position="172"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="10">
        <location>
            <begin position="257"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="355"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="403"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00069872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH59504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="413" mass="45383" checksum="05516E371CFF1461" modified="2009-05-26" version="1">MLFATYFSRIGSVAVKSSLPGARALIQLHCNKSLPLRREGHSAALLGCVRTTDVFLRSGAVLSSSCSIRHARSADVTAAYLFQHVKSRCITSFSTPSSRNSTAAERFAARTGAFHHRRPRLTRAYDRTVENTLKVCKPTSPGQRGRIITVRTELWKGKPYRPLTRGIAKTGGRGRLGRITVWHRGGGHKRRYRVVDFNKHRLRGSLGTVCRVEYDPNRTARIALVRHEGHKGPVYVLATDTMKSGDTIIADNDDQEIRPGNSMPLERMPLGTVIHNIELRPGQGGKLVRAAGAAATLIKKGNHGYAVVRLPSGEQRLVLARCYATVGIISNRSHQNRKLGKAGARRWLGVRPTVRGVSMNPVDHPHGGGEGRTSGGRPSSTPWGIQTKGKRTRNSKHSDLYRVARRSTGRKGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM98</accession>
    <name>C1MM98_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46766</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056895.1">
        <property type="nucleotide sequence ID" value="XM_003056849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM98"/>
    <dbReference type="STRING" id="564608.C1MM98"/>
    <dbReference type="GeneID" id="9682334"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46766"/>
    <dbReference type="eggNOG" id="ENOG502S5JE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498868at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="619" mass="65712" checksum="F3DB8089D1C1A9F9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMQ9</accession>
    <name>C1MMQ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_15135</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057448.1">
        <property type="nucleotide sequence ID" value="XM_003057402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMQ9"/>
    <dbReference type="STRING" id="564608.C1MMQ9"/>
    <dbReference type="GeneID" id="9682411"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15135"/>
    <dbReference type="eggNOG" id="KOG1018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VGPWRKD"/>
    <dbReference type="OrthoDB" id="659at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF149">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="6"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="189" mass="20126" checksum="6FDA8C358862042A" modified="2009-05-26" version="1">MAAFTADDERHMRAALAEATAALDRWEVPVGCVLVLDNEIVARGSNRTNERRNGTRHAEFEAIDALLAAHANDANAARFEDCVLYVTCEPCIMCAGALSLLGCRAVVYGCGNDKFGGNGSILSDGGDAAASNGARGARRTYPSVGGLFAEDAVELLRRFYVRGNPKAPKPHRTLTSESLAIRERRGADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMX8</accession>
    <name>C1MMX8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Condensin complex component, non-smc subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_56701</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CND1 (condensin subunit 1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057002.1">
        <property type="nucleotide sequence ID" value="XM_003056956.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MMX8"/>
    <dbReference type="GeneID" id="9682926"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56701"/>
    <dbReference type="eggNOG" id="KOG0414">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CPLEKLW"/>
    <dbReference type="OrthoDB" id="436262at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000779">
        <property type="term" value="C:condensed chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010032">
        <property type="term" value="P:meiotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032682">
        <property type="entry name" value="Cnd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007673">
        <property type="entry name" value="Condensin_cplx_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024324">
        <property type="entry name" value="Condensin_cplx_su1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF2">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12717">
        <property type="entry name" value="Cnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12922">
        <property type="entry name" value="Cnd1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017127">
        <property type="entry name" value="Condensin_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin complex subunit 1 N-terminal" evidence="12">
        <location>
            <begin position="83"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="11">
        <location>
            <begin position="1138"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="577"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1395"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="370"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="381"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="580"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="597"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1416"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1447"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1498"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1525"/>
            <end position="1534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH58647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1534" mass="162177" checksum="D24355603E8BE896" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNP1</accession>
    <name>C1MNP1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55979</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056682.1">
        <property type="nucleotide sequence ID" value="XM_003056636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNP1"/>
    <dbReference type="GeneID" id="9682114"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55979"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="74" mass="7839" checksum="BE781B1442071B25" modified="2009-05-26" version="1">MAAAIRFLKRGEIDEDDDVFSRLSPEVGLGEISWVAPPMREPGEDSETDPEARGDGAIAEAAAEEVGGGVKNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNP4</accession>
    <name>C1MNP4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sm protein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_9282</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056683.1">
        <property type="nucleotide sequence ID" value="XM_003056637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNP4"/>
    <dbReference type="STRING" id="564608.C1MNP4"/>
    <dbReference type="GeneID" id="9682583"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9282"/>
    <dbReference type="eggNOG" id="KOG3482">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GYMNVQL"/>
    <dbReference type="OrthoDB" id="409625at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01722">
        <property type="entry name" value="Sm_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000011">
        <property type="entry name" value="small nuclear ribonucleoprotein F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034100">
        <property type="entry name" value="Sm_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="8"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH58328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="84" mass="9240" checksum="F33119BACF1F1DC0" modified="2009-05-26" version="1" fragment="single">MAATVPVNPKPFLNQLTGKAIIVKLKWGMEYKGYLVSTDAYMNLQLASTEEYIDGKFAGNLGEVLIRCNNVLYLRGAPEDEEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNT9</accession>
    <name>C1MNT9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56028</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057169.1">
        <property type="nucleotide sequence ID" value="XM_003057123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNT9"/>
    <dbReference type="GeneID" id="9682608"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56028"/>
    <dbReference type="OrthoDB" id="414028at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="369" mass="40441" checksum="DC3DEBC08DD13600" modified="2009-05-26" version="1">MAPLYAVAFRPKSVAAGARRLARLAPPHVRHQAGVVVLSWLLVVTSGRARRAEKLFEYPAYFAWEVGAAWTVVAFAFVAACSALSFSTLNRDELAEETDDEHENDLVEERSSTPTTPRRRLTGAIGERRTETPLRSTEKRRTGWRRVITNRRAGTLPAAFIAVASACAYLGVRTYPAFAMFSNLAIEGGRTNHWIALHVLPKALTWTAPDADVDVSTLGNYYGAHVGIVVLDTDVDALKTAQVNLAPLLPTHAKEALRRAGADLDFHITPPPGSWPYGPTEETFRPFALPLAEARRRVAGVVGGRSPGDGFVTYRWVAGGRVVGATKTMKVAGGKARGGDEVLARPLPRWRAWLHRYRSFSLDESPCRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP68</accession>
    <name>C1MP68_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56165</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056768.1">
        <property type="nucleotide sequence ID" value="XM_003056722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP68"/>
    <dbReference type="GeneID" id="9682207"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56165"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="75" mass="7380" checksum="11D88B88B3948200" modified="2009-05-26" version="1">MEGGGVAGLAAMRSKMAGRGRGIDPTRPLQRMEEGGAGRGLGGLKKSSSGGGGGSTGTLLESVRYLEQGGKLSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPJ3</accession>
    <name>C1MPJ3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_56926</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057967.1">
        <property type="nucleotide sequence ID" value="XM_003057921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPJ3"/>
    <dbReference type="STRING" id="564608.C1MPJ3"/>
    <dbReference type="GeneID" id="9683023"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56926"/>
    <dbReference type="eggNOG" id="KOG2693">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FYIVERV"/>
    <dbReference type="OrthoDB" id="200954at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950">
        <property type="entry name" value="ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950:SF16">
        <property type="entry name" value="ZINC TRANSPORTER ZIP13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="166"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="438" mass="45362" checksum="BF577EA570A1E06A" modified="2009-05-26" version="1">MPSSYVRRARFDVRGFGVARLCAHALGASLATSLASLVAIAILPLLCLRVRRGGGGGGGAKRKKKTDAAADADAAARLTIPPALSALLGAFAVGALLGDAFLHQLPHAYASVRGDDARAGGHDHDHDHGGGSLLRAAIEQRIGLCACGGVVAFYIVERVVRALGSSCRGRRQHQHQNGPHHRRRHHHRAAARKKKDGDADGEEEREDGGGAATTTKRRTAARRRRAAGATSPSPPPPAARARRVAEEAFDDDDDDDDNLHVLLAEEKKVVGVMNLLADAAHNFTDGVVVGASFVVGGPRRGWAKTALILAHEIPQELGDFGALTHAGFTVARALFYNFLSALASVVGTAVALLIGGAAFVGREGGTEALSDGDADATRWMACADAFVAGGFAYAACGTAMAEMQRAGMGWRGEVGRVVAVVVGVATCALGHVASGCRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPR7</accession>
    <name>C1MPR7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57009</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057631.1">
        <property type="nucleotide sequence ID" value="XM_003057585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPR7"/>
    <dbReference type="GeneID" id="9683079"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57009"/>
    <dbReference type="OrthoDB" id="497422at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00293">
        <property type="entry name" value="USP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="1">
        <location>
            <begin position="92"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="146" mass="16412" checksum="EF760F9F593915C1" modified="2009-05-26" version="1">MDVKAQEALWAAAVLQNEQMLDGIYKKLRARHGEWTFTSLGFDFVRDTFLKGVRGWCGVSPTLTKGDMADAGDEMTPFPQPIELDCVFDTTWLPVAEEVKNIAERRGVKLLIVAHHPKKIWEQWLAGSVSKYLIDEATMPVVVVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPY3</accession>
    <name>C1MPY3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57087</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057667.1">
        <property type="nucleotide sequence ID" value="XM_003057621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPY3"/>
    <dbReference type="STRING" id="564608.C1MPY3"/>
    <dbReference type="GeneID" id="9683118"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57087"/>
    <dbReference type="OMA" id="ARMMEEN"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="615" mass="68357" checksum="7AC1202F3A6FE84E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ50</accession>
    <name>C1MQ50_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_7077</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058065.1">
        <property type="nucleotide sequence ID" value="XM_003058019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ50"/>
    <dbReference type="STRING" id="564608.C1MQ50"/>
    <dbReference type="GeneID" id="9683503"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7077"/>
    <dbReference type="eggNOG" id="ENOG502QUTY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PTPEWNK"/>
    <dbReference type="OrthoDB" id="1916780at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="169" mass="18818" checksum="0CDBA19544774759" modified="2009-05-26" version="1" fragment="single">FFGEATTSSSYGGYGGNENNFDKFKYYYEIPEGWVPDTVNKVEKSTNGTDSRWVNPKNKDQKVYCVTLTGYNKLKEDRTGILGDLALSDYNLQDALTGADSTIVNEREENGQTYVDFDLLGYFGAIYATVTVYGGRVYALFSICPESLLESGSEQAMRMRKSFGTIAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQJ0</accession>
    <name>C1MQJ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57309</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058133.1">
        <property type="nucleotide sequence ID" value="XM_003058087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQJ0"/>
    <dbReference type="STRING" id="564608.C1MQJ0"/>
    <dbReference type="GeneID" id="9683207"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57309"/>
    <dbReference type="OMA" id="WFERIDV"/>
    <dbReference type="OrthoDB" id="10691097at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
        <property type="entry name" value="PHEROMONE SHUTDOWN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530:SF7">
        <property type="entry name" value="TRAB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="619" mass="63923" checksum="D0386AEB5E5607E8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQY7</accession>
    <name>C1MQY7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LHCP4</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_57460</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057837.1">
        <property type="nucleotide sequence ID" value="XM_003057791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQY7"/>
    <dbReference type="STRING" id="564608.C1MQY7"/>
    <dbReference type="GeneID" id="9683650"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57460"/>
    <dbReference type="OMA" id="HCRLAMG"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="237" mass="24932" checksum="5174CFAD5DC0E299" modified="2009-05-26" version="1">MAALTMSASLVKVALPTAGARKTTARRAAVKVSANLWPEPGTYPGAPDADTVSPLGNDDVLSMNKAAEYEVIHGRWAMLAIPGIVAQEQATGVPWYDTGALCTPASCLENYSFPGAPAPLAPEGSGAPYFWAVLAFEVVAVGLAEAYRGGIVSPPKGFPEPSLYPGGRFDPLGFAEKGDLEKLKLQELKHCRLAMGAFLGCLVQKEFTGVGPVANLTSHISDPTHNFFGSQTAPWNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR24</accession>
    <name>C1MR24_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_16180</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057855.1">
        <property type="nucleotide sequence ID" value="XM_003057809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR24"/>
    <dbReference type="GeneID" id="9683293"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16180"/>
    <dbReference type="OrthoDB" id="496415at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013111">
        <property type="entry name" value="EGF_extracell"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07974">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epidermal growth factor-like" evidence="2">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="85" mass="9522" checksum="0C60C51D8DF4A229" modified="2009-05-26" version="1" fragment="single">MDPFYRDATPSRGVAERARNFPQELRALEQRERHLLSLFGEAQVECTGHGACDYGAGQCYCASRYFGTACEYTFCKNDCAGHGRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRJ2</accession>
    <name>C1MRJ2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57673</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057937.1">
        <property type="nucleotide sequence ID" value="XM_003057891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRJ2"/>
    <dbReference type="STRING" id="564608.C1MRJ2"/>
    <dbReference type="GeneID" id="9683375"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57673"/>
    <dbReference type="OrthoDB" id="542001at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF30">
        <property type="entry name" value="ACETYL-HYDROLASE LIPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="120"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="248" mass="26379" checksum="C79EA4AF18C3DB71" modified="2009-05-26" version="1">MARYGGGALRKSRTKGAFPDSWSLPFAVGVELLAGFLEAVTITEDEMIGVRAGDERALRAIGAYVKVLRGAMAVGVPPLPCFSLSVVDPSRGGTRAERVRANGVPAVWLTPPQYASTKTIMWMHGGAFIFCHTGTHARLLSSLGAAADAKVLSVEYSLCPDEGRYADMLREVTRAYEWLVDADGGGADPKDVVVGGDSAGGHLALGLIAELAKKKREEEDGGGGARENQVRSIHWSPYDRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRJ3</accession>
    <name>C1MRJ3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57674</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057938.1">
        <property type="nucleotide sequence ID" value="XM_003057892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRJ3"/>
    <dbReference type="GeneID" id="9683376"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57674"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="150" mass="16064" checksum="E5333C381349EE83" modified="2009-05-26" version="1">MPSGVLLMSPWLDPEREHPDTAKAWSDADSGDSFDYLRGVEGSLKTVADLVFGCDVDGVCDESIARCLVRGDVWDDADVAYPPVFVQYGGAEVLAAESRTFARVVNASRSSMVVELEEWADMPHVFQVFDAVAAAGGDAIASAAAFVKRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRL8</accession>
    <name>C1MRL8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_39830</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058897.1">
        <property type="nucleotide sequence ID" value="XM_003058851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRL8"/>
    <dbReference type="GeneID" id="9683970"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39830"/>
    <dbReference type="OrthoDB" id="10653132at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="285"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="56"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="358"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="556" mass="56088" checksum="123720335CA2D0F8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRR2</accession>
    <name>C1MRR2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_58196</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058919.1">
        <property type="nucleotide sequence ID" value="XM_003058873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRR2"/>
    <dbReference type="GeneID" id="9683992"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58196"/>
    <dbReference type="eggNOG" id="ENOG502S6HQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="195057at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39188">
        <property type="entry name" value="MEMBRANE-ASSOCIATED ZINC METALLOPROTEASE M50B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39188:SF3">
        <property type="entry name" value="STAGE IV SPORULATION PROTEIN FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M50" evidence="14">
        <location>
            <begin position="216"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="295"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH57374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="446" mass="46565" checksum="45BC6CD25EC6D699" modified="2009-05-26" version="1">MATLRRLAASGLAGEVLAAVGVSSRGAAFARTAASSAFRPRAPWTRAPTNARSSPTRLLHVGTRAHQPVVKATAAPLTARGALETLGVRTPWRPGALASPTSGVATRRVSHHFKWRKQVPRRPSPGVAGALVPSARRHLWTNSRVPPGGSGAGGTIGSLIRAARKFGAALALPFVLLWKYKFAALSALKLTKLSSLASLALSTAAYAALYGVPYGVGIMAQIVIHESGHAIALMRYGVPFQPMVFVPLMGAYVSHAGMLSAWKNAFVALAGPFAGGVGALGLYLMGVALTESEGGETASSRERRLGRTPNVRDRARDRVRERGAEKTTAQLCHALADFGCMINLFNLLPMGMLDGGQVAAVLHPSLLVAGCAVGSYMAYDGQINNPIVYLIILGGWYQVASRAMGWSQPNPAAAHLSPRGKAIVFGAYAGLAARGCTGRGGNLRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS76</accession>
    <name>C1MS76_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58376</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059000.1">
        <property type="nucleotide sequence ID" value="XM_003058954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS76"/>
    <dbReference type="GeneID" id="9684439"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58376"/>
    <dbReference type="eggNOG" id="ENOG502QWSX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="185024at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="313" mass="33386" checksum="7A79A4D8727A2008" modified="2009-05-26" version="1">MAATVATMDGSLGFDAVVVCTSNAAQEAYWQERLERTRGQAAKKGAVIVAVHEDWASDGAGNGLGTLYAYAKARAQAMARVDGAVDLDAMLAEGKTVGIYHTAGKGTRLAPLPGAENNNKPGVKLPSLVTVEGARADDPPTTSELTILEAVIRQTGCYAPRRAGRCSVFWGDQIFVPSAGHLPSGAHHADILARMGPMPTEEEWAAKGLEKYGLIAVNAADEAAQVEKVSYDTAMKLLGSFGEVKRVGPSLGSFSLGAEMLRMLLEEFATELEEKRAKMDSDPHLWMPMTLDKARSISHWSPYDRVGDVDAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSB1</accession>
    <name>C1MSB1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Gliding motility related cam kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_58417</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058650.1">
        <property type="nucleotide sequence ID" value="XM_003058604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSB1"/>
    <dbReference type="STRING" id="564608.C1MSB1"/>
    <dbReference type="GeneID" id="9684460"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58417"/>
    <dbReference type="eggNOG" id="KOG0032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EMAYLAP"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000315">
        <property type="entry name" value="Calcium-dependent protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0140">cGMP</keyword>
    <keyword evidence="7" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="62"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="352"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="469"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH57105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="499" mass="54394" checksum="AEA6B137A30FE459" modified="2009-05-26" version="1">MGSKASKAKNKVKNGGVQSATAGSTPPSSRDPSARGGSQNSRRNSLDREQTLKNVRKVQDVYEMKSVLGTGGYAVVWGAVHKRTRQEYAIKVMKATSSSNPNDDEVSVDEIRNEIEVMKRIEHPNIVHVREYFVQNGKFYIVMGWLKGGELLDALLDLGNYTEQDAKVIARQLLEALSYMHVNNVIHRDLKLENLLLARPNDISSVVIADFGLARKAVNARQVFTTQCGTPSYVAPEILLGQSYTPAVNVWSMGVILYTLLIGSFPYAHSDQQTLFRIICSGKFQTSQPEWEQIGPEVKDLLRGLLCVDVKERLTAADALNHAWFTADNDASSKNLKASRARLHTFADSMKLQVKTFEPGAFLVRQGELGHEVYLIREGTCDVTVANANGSVSKVATRGKGDFIGEMAVSSEDGDAAAKPRTASVRAVDFVSATVLSKADMQWAVDHDYSLEGEIRSVIEARRAELDDASHRGGNEYSPDGGGGGADALGDGVAAMELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT96</accession>
    <name>C1MT96_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protofilament ribbon protein of flagellar microtubules</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RIB72</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_33490</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058450.1">
        <property type="nucleotide sequence ID" value="XM_003058404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT96"/>
    <dbReference type="STRING" id="564608.C1MT96"/>
    <dbReference type="GeneID" id="9684265"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33490"/>
    <dbReference type="eggNOG" id="KOG0043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RFSCKQP"/>
    <dbReference type="OrthoDB" id="10255210at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.170:FF:000002">
        <property type="entry name" value="EF-hand domain (C-terminal) containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.170:FF:000001">
        <property type="entry name" value="EF-hand domain containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.170:FF:000004">
        <property type="entry name" value="EF-hand domain containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.170">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006602">
        <property type="entry name" value="DM10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040193">
        <property type="entry name" value="EFHC1/EFHC2/EFHB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086">
        <property type="entry name" value="EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086:SF9">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06565">
        <property type="entry name" value="DM10_dom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00676">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51336">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DM10" evidence="7">
        <location>
            <begin position="76"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="DM10" evidence="7">
        <location>
            <begin position="246"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="DM10" evidence="7">
        <location>
            <begin position="417"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="621" mass="69299" checksum="1932E1EC6E75DC4D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTC3</accession>
    <name>C1MTC3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_39753</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058463.1">
        <property type="nucleotide sequence ID" value="XM_003058417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTC3"/>
    <dbReference type="GeneID" id="9683902"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39753"/>
    <dbReference type="eggNOG" id="KOG1676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MIMELQT"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02393">
        <property type="entry name" value="KH-I_PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="158"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="240"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="319"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="421"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="642"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="675" mass="65573" checksum="E66F990DD96D5195" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTI8</accession>
    <name>C1MTI8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pub domain/WLM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_70863</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058871.1">
        <property type="nucleotide sequence ID" value="XM_003058825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTI8"/>
    <dbReference type="STRING" id="564608.C1MTI8"/>
    <dbReference type="MEROPS" id="M80.A02"/>
    <dbReference type="GeneID" id="9683936"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70863"/>
    <dbReference type="eggNOG" id="KOG4842">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="49605at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10463">
        <property type="entry name" value="PUB_WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47796:SF1">
        <property type="entry name" value="OS08G0500800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47796">
        <property type="entry name" value="ZINC METALLOPROTEINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WLM" evidence="2">
        <location>
            <begin position="148"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="626" mass="63759" checksum="4EA3706C691C1DAC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTN9</accession>
    <name>C1MTN9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_17183</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058525.1">
        <property type="nucleotide sequence ID" value="XM_003058479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTN9"/>
    <dbReference type="STRING" id="564608.C1MTN9"/>
    <dbReference type="MEROPS" id="T01.986"/>
    <dbReference type="GeneID" id="9684333"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17183"/>
    <dbReference type="eggNOG" id="KOG0179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CSGCWCD"/>
    <dbReference type="OrthoDB" id="268479at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03757">
        <property type="entry name" value="proteasome_beta_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000027">
        <property type="entry name" value="Proteasome subunit beta type-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="220" mass="24476" checksum="5DBD6E7FAFAFAEBA" modified="2009-05-26" version="1">MRQNWSPYDNNGGTVLAVAGEDYVVCAADTRMSTGYSVLTRDYKKIEKMTEKCVMASAGFMADAVTLKKTLKARCVSYEFQNNKEMGCVSFAQMLSNTLYYRRFFPYYTFNIVAGLDKEGKGAVFTYDAVGSYERTNYSCQGSGQGLIMPVLDNQLKTVSPLVLPAQSSATPLSESEAVDLVKDCFATAGERDIYTGDSVEIWIINKDGLRKEYQDLKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUB1</accession>
    <name>C1MUB1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_9869</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059465.1">
        <property type="nucleotide sequence ID" value="XM_003059419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUB1"/>
    <dbReference type="STRING" id="564608.C1MUB1"/>
    <dbReference type="GeneID" id="9684605"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9869"/>
    <dbReference type="eggNOG" id="KOG4628">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IRECCIC"/>
    <dbReference type="OrthoDB" id="21204at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051653">
        <property type="entry name" value="E3_ligase_sorting_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168:SF1">
        <property type="entry name" value="OS02G0798600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168">
        <property type="entry name" value="RING ZINC FINGER DOMAIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="4"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="50" mass="5643" checksum="57B6442B75E301D9" modified="2009-05-26" version="1" fragment="single">AKTCTFCLDDYDDGDALRTLPECGHQFHVDCVDPWLTTKRACCPVCKHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUH5</accession>
    <name>C1MUH5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58808</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059199.1">
        <property type="nucleotide sequence ID" value="XM_003059153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUH5"/>
    <dbReference type="STRING" id="564608.C1MUH5"/>
    <dbReference type="GeneID" id="9684935"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58808"/>
    <dbReference type="eggNOG" id="KOG2134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19045at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046404">
        <property type="term" value="F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046403">
        <property type="term" value="F:polynucleotide 3'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006551">
        <property type="entry name" value="Polynucleotide_phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01664">
        <property type="entry name" value="DNA-3'-Pase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="288" mass="30060" checksum="AF91567184A6BBED" modified="2009-05-26" version="1">MENFFKRKDPPPGAPAGGPNPKTACTSSTSPSSSSAPRWSTHHDALLARTEAACAPCAKIAAFDLDDTLQKTRSGQKGYMVTDVNDFVDWSADVAPTLRRLHATGYKIVIFSNQGGVKGAMTGKRADVVRRRIDAFARAAGVPLQAFCATQKGVDKDPRSYRKPGAGMWKLATSAAFNGGVEVNVAECFFVGDAAGRAGDFSASDKEFAAGAGVRFMTPEEAFNAPGCAPAGPGDGGGREDGEGAAEDANTKMESAVCAKEGGEGVIVIDDDDDEVDKKMASLRDDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV21</accession>
    <name>C1MV21_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="11">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MICPUCDRAFT_34035</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="11"/>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059599.1">
        <property type="nucleotide sequence ID" value="XM_003059553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV21"/>
    <dbReference type="STRING" id="564608.C1MV21"/>
    <dbReference type="GeneID" id="9685039"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34035"/>
    <dbReference type="eggNOG" id="KOG0944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FVPCEHT"/>
    <dbReference type="OrthoDB" id="361536at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14386">
        <property type="entry name" value="UBA2_UBP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000086">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016652">
        <property type="entry name" value="Ubiquitinyl_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041432">
        <property type="entry name" value="UBP13_Znf-UBP_var"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF664">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17807">
        <property type="entry name" value="zf-UBP_var"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016308">
        <property type="entry name" value="UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 11" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10 11 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="18">
        <location>
            <begin position="164"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="17">
        <location>
            <begin position="324"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="639"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="714"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="502"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="612"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="694"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="769"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="769"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="12">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="815"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH56731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="854" mass="91106" checksum="E6A701DBB24FECFC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVA3</accession>
    <name>C1MVA3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_45625</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059632.1">
        <property type="nucleotide sequence ID" value="XM_003059586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVA3"/>
    <dbReference type="STRING" id="564608.C1MVA3"/>
    <dbReference type="GeneID" id="9684780"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45625"/>
    <dbReference type="eggNOG" id="KOG2903">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YQLFVSY"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03190">
        <property type="entry name" value="GST_C_Omega_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047047">
        <property type="entry name" value="GST_Omega-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="GLUTATHIONYL-HYDROQUINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015753">
        <property type="entry name" value="GST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="157"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="143"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="316" mass="35902" checksum="8885DDBBB1A032A2" modified="2009-05-26" version="1">MQVHLTGFLEHNAAAGRYHLYVSYACPWASRCLSVLGLKGIGRDVVSVSSVHPTWAKTRPDDVDDAHCGWRFWREDDDDDATVSNPAGVGAFPGGAKYNCTADDLHGVTYVRDLYDMVNAPKGTRFTVPILWDKKTNSIVSNESADIIRDLYTQFDAFAKNPDLDLYPEALRDEIDAVNEWVYHGINNGGAYEEAVNELFRCLDRAEEILSKRRYIAGDVLTEADVRLFPTLVRFDEVYVVYFKCNRKFIHQYPNLHNYVLDVYQTPGMRESVDMWHIKTHYFTSHPGLNQHAVVPVGPGVDLDAPHDRARFEKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVG3</accession>
    <name>C1MVG3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_59368</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in intercistronic processing of primary transcripts from chloroplast operons. The endonucleolytic activity of the enzyme depends on the number of phosphates at the 5' end, is inhibited by structured RNA, and preferentially cleaves A/U-rich sequences.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase E/G family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059746.1">
        <property type="nucleotide sequence ID" value="XM_003059700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVG3"/>
    <dbReference type="STRING" id="564608.C1MVG3"/>
    <dbReference type="GeneID" id="9685472"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59368"/>
    <dbReference type="eggNOG" id="ENOG502QPXM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AWLAYGK"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001:SF1">
        <property type="entry name" value="RIBONUCLEASE E_G-LIKE PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding protein AU-1/Ribonuclease E/G" evidence="11">
        <location>
            <begin position="573"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="103"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="203"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="350"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="423"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="863"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="107"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="431"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="868"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="899"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="914"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="985"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="1031"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1050"/>
            <end position="1060"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH55698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1060" mass="111128" checksum="51A76FFB93CE453F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVJ5</accession>
    <name>C1MVJ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_27563</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060048.1">
        <property type="nucleotide sequence ID" value="XM_003060002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVJ5"/>
    <dbReference type="STRING" id="564608.C1MVJ5"/>
    <dbReference type="GeneID" id="9685203"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27563"/>
    <dbReference type="eggNOG" id="KOG0374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SERGPMW"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546:SF4">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="278" mass="29963" checksum="6EAD545745B13151" modified="2009-05-26" version="1" fragment="single">MKALECAKVMDKTGKWCGGDTVVVQVGDILDRGDNELAIMRKFRALAKDARAAGGDFIVINGNHEIMNVLGDFRYVTKGAYGECARYTEKKRLAQIAKLGEENVEPPPETPEGVNPQTYAGLLARRALFLPGGEMAVKMASNPTVLQVDDTVFAHAGIDESHVEYGFARINAEVSQWMAGSRAQPPKHVLEEKGVVWTREYGGADAGQTSEAAACRRLEKALDATGAKRIVIGHTPQQKGVNSGCGGKVWRADVGASRGIYGNTPQVIEIVNGRVRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVL2</accession>
    <name>C1MVL2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59418</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060057.1">
        <property type="nucleotide sequence ID" value="XM_003060011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVL2"/>
    <dbReference type="GeneID" id="9685211"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59418"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="403" mass="44136" checksum="79BACF31D3063EEA" modified="2009-05-26" version="1">MSATDPTPPAAKRARRAAAPPSPPSPSPSPPAPSPFERFAAVARDGAKFELLKRLDPLSRGMLARTCRAWRDDVEFFGLASAGVAGSRKLRARAFVNTVERVRWATANGLTLDARVAALAARRGKLDVLKYLQTAGCALDARAVAAAARGGHLDVIEWAIERGCATDARACAQAARGGHLDLLKTLRAKTNFPWDASTPSAAARGGRLDVVRWLDEQKCPRDEKAVCAMAARSGNVELVKWVISRYEWDVWTPGLAARGGHVEILRLVWATKPDCFNDVVSMCAAKGGHWRVMDWISNHRRHAIQMWSHRVFEGWIAPYAAEHGRAFFDKTVESCGGPVNLVYLNGLKCAISAVATGNVDLLLRINELAHRKNPVSLYYDIATGAERRNITMEDLNPLRKQHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWF9</accession>
    <name>C1MWF9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59752</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059917.1">
        <property type="nucleotide sequence ID" value="XM_003059871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWF9"/>
    <dbReference type="GeneID" id="9685356"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59752"/>
    <dbReference type="OMA" id="YACHELP"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="712" mass="77019" checksum="349D54A2F1A48A70" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWN8</accession>
    <name>C1MWN8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_45632</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059958.1">
        <property type="nucleotide sequence ID" value="XM_003059912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWN8"/>
    <dbReference type="GeneID" id="9685117"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45632"/>
    <dbReference type="eggNOG" id="KOG1277">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WKETQIP"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF168">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007360923" description="Transmembrane 9 superfamily member" evidence="9">
        <location>
            <begin position="28"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="505"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="539"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="575"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH55910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="614" mass="70154" checksum="B4780C5E34322A3A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX34</accession>
    <name>C1MX34_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_19041</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA2 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060621.1">
        <property type="nucleotide sequence ID" value="XM_003060575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX34"/>
    <dbReference type="STRING" id="564608.C1MX34"/>
    <dbReference type="GeneID" id="9685767"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19041"/>
    <dbReference type="eggNOG" id="KOG3446">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FIEQQYV"/>
    <dbReference type="OrthoDB" id="10250268at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016464">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12878:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12878">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005822">
        <property type="entry name" value="NDUA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH55390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="95" mass="10226" checksum="2D43ABED54A0C46D" modified="2009-05-26" version="1">MSKAAFAGLKAVQEIRFHLCQTSKGSEGVRNFLLKSYKAMKAASPTTPILIREASGVEGGFVARYDFGVEKKFSLEGLDAKAVEKEVTGVLKQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXD3</accession>
    <name>C1MXD3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_40945</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060375.1">
        <property type="nucleotide sequence ID" value="XM_003060329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXD3"/>
    <dbReference type="GeneID" id="9686111"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40945"/>
    <dbReference type="OMA" id="ATEMMHE"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="339"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="236"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="373" mass="38164" checksum="B25F548A26AB640E" modified="2009-05-26" version="1">MIRRPKEHFPAANGADGARANGAKVTSSSFFPPSSHPGAANGGATRRVDAAGGAGRNNFAAPPRQPVAAPRTRRDGVGGASGAEADPNPLRAGAPSSGAGAGGWVSTRGQLHPRDGGGAAGMAAARSRAPYLPRSPPSSTSSAAAQTDAIDPSTASTPNAQLRFQASLQRELRDAKEELVRAQLENVALASRLRESSSPGASSRRGAESDVTCGTIAGMLSEEDADERRRELLEAIRDERDARGRVEERARALEAELSAKDDKLRAATEMMHEMREALVEAYDGTAHGAGRDAGPAGTTTRGGKSGADDDDDAAAATATAATATAVSPGDMAAGAVKGVVSLVGVLVGTAGFELVWPLVLAALWLRYQLWSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXE0</accession>
    <name>C1MXE0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60123</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060378.1">
        <property type="nucleotide sequence ID" value="XM_003060332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXE0"/>
    <dbReference type="GeneID" id="9686115"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60123"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="143" mass="15286" checksum="CD77E8DC1DE38383" modified="2009-05-26" version="1">MPPKAKPICMYENCDAPAVRVCIARCGRILCDAHGSLIDPGYVDDAGGKWYQACNACDAAVCQHCGGGEGLGIPCSYSLINGNNKCEGCARNKRPAKKKPKKAPKKKAPKKAPKKDPKKEKRIPGHGKNLAPKKTLEKKSSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXX4</accession>
    <name>C1MXX4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_69232</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060466.1">
        <property type="nucleotide sequence ID" value="XM_003060420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXX4"/>
    <dbReference type="STRING" id="564608.C1MXX4"/>
    <dbReference type="GeneID" id="9686211"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69232"/>
    <dbReference type="OMA" id="EARYIVQ"/>
    <dbReference type="OrthoDB" id="513812at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20261">
        <property type="entry name" value="Complex1_LYR_LYRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045294">
        <property type="entry name" value="Complex1_LYR_LYRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040330">
        <property type="entry name" value="LYRM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14273">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14273:SF0">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="3">
        <location>
            <begin position="56"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="145"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="217" mass="23268" checksum="C70DC7729E1A79FE" modified="2009-05-26" version="1">MLKGYFHRKSRSKAFNTSCTTLYSGASSTLPIDFVAAHIERRAPPPPREAMASTRQRALSLMRSMLRCSMGWQGDRGRREAEYIVLETSKAFRARRDATDPALVERYLREGEERLYMANNYKIAYARLPHVALGGGGDVKNVLPPAQMPGDDDAGGSGGGRWTGGGDGGSRGGHVGGSLRLASASTPVNPRLNAARAAARAKRAAMSKATATDEADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYG8</accession>
    <name>C1MYG8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_69312</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060827.1">
        <property type="nucleotide sequence ID" value="XM_003060781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYG8"/>
    <dbReference type="STRING" id="564608.C1MYG8"/>
    <dbReference type="GeneID" id="9685964"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69312"/>
    <dbReference type="eggNOG" id="KOG2194">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF22">
        <property type="entry name" value="ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="5">
        <location>
            <begin position="2"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="682" mass="70512" checksum="463934495F78EDC5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYJ1</accession>
    <name>C1MYJ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_34472</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060576.1">
        <property type="nucleotide sequence ID" value="XM_003060530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYJ1"/>
    <dbReference type="STRING" id="564608.C1MYJ1"/>
    <dbReference type="GeneID" id="9686270"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34472"/>
    <dbReference type="eggNOG" id="ENOG502QPKQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KSAMCWV"/>
    <dbReference type="OrthoDB" id="73273at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31652">
        <property type="entry name" value="LIMR FAMILY PROTEIN DDB_G0283707-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31652:SF0">
        <property type="entry name" value="LIMR FAMILY PROTEIN DDB_G0283707-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="479"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="518" mass="56942" checksum="2E5D3D7D73469DF4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYR1</accession>
    <name>C1MYR1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_19362</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060319.1">
        <property type="nucleotide sequence ID" value="XM_003060273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYR1"/>
    <dbReference type="STRING" id="564608.C1MYR1"/>
    <dbReference type="GeneID" id="9685757"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19362"/>
    <dbReference type="eggNOG" id="KOG2175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YHRYMIS"/>
    <dbReference type="OrthoDB" id="27483at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072542">
        <property type="term" value="F:protein phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055236">
        <property type="entry name" value="EVH1_PP4R3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006887">
        <property type="entry name" value="P4R3-like_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051137">
        <property type="entry name" value="PP4R3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318">
        <property type="entry name" value="ATP SYNTHASE GAMMA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22972">
        <property type="entry name" value="EVH1_PP4R3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04802">
        <property type="entry name" value="PP4R3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PP4R3 EVH1-like" evidence="5">
        <location>
            <begin position="22"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central" evidence="4">
        <location>
            <begin position="155"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="641"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="664"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="682"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="693"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="725"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="760"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="776"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="790" mass="87639" checksum="AC013ED480B1216E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYT7</accession>
    <name>C1MYT7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_60478</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0696 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061096.1">
        <property type="nucleotide sequence ID" value="XM_003061050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYT7"/>
    <dbReference type="GeneID" id="9686280"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60478"/>
    <dbReference type="OMA" id="ATYAGMY"/>
    <dbReference type="OrthoDB" id="6434934at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015034">
        <property type="entry name" value="Bles03"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014905">
        <property type="entry name" value="HIRAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977:SF1">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08797">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIRAN" evidence="4">
        <location>
            <begin position="73"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="397" mass="42171" checksum="7B94898EF8698AEC" modified="2009-05-26" version="1">MPLMLKRQYDALAAAATGDAPKKSALEPERAPVVEISNDERATDENENAVVVIDDDDNDAPRDAVVSARLVGSMRHRAARARLAHGAKLRLRRDDGNAHDPNAVAVDVLSSSVGDPIHAGFVKATQAAVLAPALDSGALTVVACVVDAPRGVDALPTKDVPVRFTLRRRSADDASAASVLELLGLPYDVPSSVGELVSPKLLDGKFAEPMSHRWLTHYDFTKPSVFAALNPVTEASPEKEWVYVNGRDENVSSEDAASAHTYSGKWMIMGVKSDVIDRYFVECAKAVEAGEVVAAKAPAGGGEGGVGVLILYTKDFRDRVEAERAGVALKRRFGSGVHLKYKTDSATYAGMYATGGGKGGGKTCCYEMKSGSLTMDVDERVYTECLKLAENGGGDYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ48</accession>
    <name>C1MZ48_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial carrier family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_34885</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061153.1">
        <property type="nucleotide sequence ID" value="XM_003061107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ48"/>
    <dbReference type="STRING" id="564608.C1MZ48"/>
    <dbReference type="GeneID" id="9686334"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34885"/>
    <dbReference type="eggNOG" id="KOG0766">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WGIYEEL"/>
    <dbReference type="OrthoDB" id="1924968at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015187">
        <property type="term" value="F:glycine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904983">
        <property type="term" value="P:glycine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181:SF3">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="19"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="123"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="222"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="309" mass="33060" checksum="49C89E9666382ADE" modified="2009-05-26" version="1">MGRQRDDGGETSETKRSPESGVTSFLAGSSAGLVSSGILQPFEVIKTRMQAHKLRPGSINKSMFKTAGCVVRDEGIRGLWSGVTASCVRTAAGAGLYFLLLERVTKEVNARFPESPNASQSSVALMKTFAVGAVSRSLAATLLCPLTVVKTRMEYTSMSGTAYTGVTNALVTIGRTEGMRGLFSGLGSTLLRDAPFSGLNLVVYTQTRKMMQDMRAKEGRAMTPFDTFVAGAISGGVATFLTHPPDVLRTRIQLRSVNVTFASVVADEGIRALWVGSLPRIARRTLQQAMTWSLYEYVAKNLGGTALSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZY8</accession>
    <name>C1MZY8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Set domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60905</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061302.1">
        <property type="nucleotide sequence ID" value="XM_003061256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZY8"/>
    <dbReference type="GeneID" id="9686475"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60905"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TFRSWLW"/>
    <dbReference type="OrthoDB" id="497755at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF91">
        <property type="entry name" value="PROTEIN SET DOMAIN GROUP 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="32"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="536" mass="57325" checksum="DA12608816879255" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N035</accession>
    <name>C1N035_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_41448</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061326.1">
        <property type="nucleotide sequence ID" value="XM_003061280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N035"/>
    <dbReference type="GeneID" id="9686498"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41448"/>
    <dbReference type="eggNOG" id="KOG2365">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FTVNIAR"/>
    <dbReference type="OrthoDB" id="552492at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 245"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="559"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="585"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="634"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="115"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="297"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="676"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="676"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="702"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="746" mass="75138" checksum="10BB86DADB5D8736" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0B9</accession>
    <name>C1N0B9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_20475</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061608.1">
        <property type="nucleotide sequence ID" value="XM_003061562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0B9"/>
    <dbReference type="STRING" id="564608.C1N0B9"/>
    <dbReference type="GeneID" id="9687047"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20475"/>
    <dbReference type="eggNOG" id="KOG3497">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MCHVDLI"/>
    <dbReference type="OrthoDB" id="10258858at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000024">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023580">
        <property type="entry name" value="RNA_pol_su_RPB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020789">
        <property type="entry name" value="RNA_pol_suN_Zn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000268">
        <property type="entry name" value="RPABC5/Rpb10"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003089">
        <property type="entry name" value="PRK04016.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431:SF9">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT 10-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01194">
        <property type="entry name" value="RNA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005653">
        <property type="entry name" value="RNA_pol_N/8_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46924">
        <property type="entry name" value="RNA polymerase subunit RPB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01112">
        <property type="entry name" value="RNA_POL_N_8KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="74" mass="8686" checksum="A63AD743E0569A5E" modified="2009-05-26" version="1">MIIPVRCFTCGKVIGNKWDTYLDLLQADYSERDALDALDLNRYCCRRMLMCHVDLIEKLLNYNTLERVDANAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0I4</accession>
    <name>C1N0I4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48218</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061395.1">
        <property type="nucleotide sequence ID" value="XM_003061349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0I4"/>
    <dbReference type="STRING" id="564608.C1N0I4"/>
    <dbReference type="GeneID" id="9687085"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48218"/>
    <dbReference type="eggNOG" id="ENOG502QQBM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YEKRLPW"/>
    <dbReference type="OrthoDB" id="45571at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35757">
        <property type="entry name" value="THERMOSOME SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35757:SF1">
        <property type="entry name" value="THERMOSOME SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="507" mass="54161" checksum="94F7EE291121A759" modified="2009-05-26" version="1">MSSASRLARASTASTSSPSPSPSPRRRPATRAPRRARSVRRGVVAEDREGREKRVSAPAPAPAFAAPPRLARAARPEPPKEYLRLVELADGGWELQSATATFRAPRGDDDDDDDDAVEISLTSTVHVGEPSYYAALQEECDARYDAVLFELITSEENLRPGRAPPPRDADGTRRRRDKNSDSDDDDFLPALAARLSPTPDARALAEAHGLRAQLDALDLQRDRWFVADLPRSVLMRAQVEAGERGAQLSRDDASAAASAAALPPALEALVVTATGRAGGGPARQLTRSMCWLVPCPEAHLLLLDWVWGGGRPAPALGATLDAIASGDVMAARRLAFAQMIVSAQAKGAVGGGADVPVLVLRRNDAAIECVRKAAATRGVNRIALLYGGLHMPGLTSKVMNELGYEITGAPSWRAVWKIDGPSSRSAVARSRSAVWRWAALPLLLLVDGADWAFTLSDVAASPATAAIEIGLYVVRHGAVYYGLGKWVLEWNRQLFDDRGGGGERGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0J2</accession>
    <name>C1N0J2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Glycosyltransferase family 28 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_4541</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061400.1">
        <property type="nucleotide sequence ID" value="XM_003061354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0J2"/>
    <dbReference type="STRING" id="564608.C1N0J2"/>
    <dbReference type="GeneID" id="9686839"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4541"/>
    <dbReference type="eggNOG" id="ENOG502QT0H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AADMMLC"/>
    <dbReference type="OrthoDB" id="20273at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03785">
        <property type="entry name" value="GT28_MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015:SF22">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="10">
        <location>
            <begin position="3"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 28 C-terminal" evidence="11">
        <location>
            <begin position="200"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH54030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="383" mass="40052" checksum="0A21FE8FED1A8E7A" modified="2009-05-26" version="1" fragment="single">LRVLFAAGGTGGHVFPAIAIADELTRLAREGGLPPPFARVRCDFAGTSTRRESTAVPSAGYSLSVVPVAELARPWASSPTNLTLPFRLAAATRAAMSLVDKLRPHVVVGTGGYVSLPTCVAAVLKRVPLVIQEQNAVPGVANAILARAATTRCAAFASAADALGGKCVVRGNPTRASLRVMTKTVARERLQRPGDENEKVLVVLGGSLGAAAVNDAIAAAAPALLASFPNLRILWQCGEKALAGTREKHAEVTSHPRVLLTPFVRDVDVAYAAADLVVARAGAVTCAELLATRTPSVLIPSPNVAEDHQTANAVEMEANGAATVVREAELREGWIEFAAATKALLVDDERLGRMREAAGRADTPDAARRIAFDVIHAAKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0Q0</accession>
    <name>C1N0Q0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">HlyC/CorC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_1575</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061678.1">
        <property type="nucleotide sequence ID" value="XM_003061632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0Q0"/>
    <dbReference type="STRING" id="564608.C1N0Q0"/>
    <dbReference type="GeneID" id="9686869"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_1575"/>
    <dbReference type="eggNOG" id="KOG2118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TIGRQHP"/>
    <dbReference type="OrthoDB" id="5353557at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.580.10:FF:000002">
        <property type="entry name" value="Magnesium/cobalt efflux protein CorC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22777">
        <property type="entry name" value="HEMOLYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22777:SF17">
        <property type="entry name" value="UPF0053 PROTEIN SLL0260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="CNNM transmembrane" evidence="10">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="192"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="259"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH54308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="402" mass="43912" checksum="66A124B9AC8F4893" modified="2009-05-26" version="1" fragment="single">LLVVYAFFAISETAITTLWPWKVREISDQEGPDSPFTLLRRDINRFLTTILIGSTVSGIASATVATEAALTIWGEGGVGPMTLALTLVTLVCCEIAPKSIAVQHAAAVARVVIPVIATLSHFVYPLGRVCAGAVNFVFSLFGIRGSAEPFVSEEELKLVLSGAAKSGQVDSDESEMIQNVLEMSETPVREVMTPLVRVVGVDQSASLHELQKIWREHRYSRVPVYNDRIDNIVGVVYSMRLLEYDMGAEMLSKVSVEGLTQKPPFYVPESMSVVKLMRELLARKTHMCIVVNEFGGTIGIATFEDCVEEIVGEIYDETDDREPASSDYVRAVKGQTDVYDVDYRAQVSDLGDALGVDIPSSALYDTVGGFTCDCFDRIPATGETILITLPAQTGYLEDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0Y6</accession>
    <name>C1N0Y6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL4m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_20384</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061477.1">
        <property type="nucleotide sequence ID" value="XM_003061431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0Y6"/>
    <dbReference type="STRING" id="564608.C1N0Y6"/>
    <dbReference type="GeneID" id="9686917"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20384"/>
    <dbReference type="eggNOG" id="KOG1624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EFYYPDA"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_uL4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF6">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="42"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="218"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="252" mass="28030" checksum="1508FB78E70EFDF5" modified="2009-05-26" version="1" fragment="single">DKTLPVFTIDGTPTGETLILPGRHFDQPLRVDLVHRVVHWQRNKARKGRKKTKTRGEVSGTTRKARPQKGGGRARVGSLRAPQMRGGGVAHGPVVRSYETALNKRVRRAGLKVALSAKLAEGRVMLVRSTHDGVEPKTKWLDERLDKLLGNQSLAAGERSHSTWISNAKRASRNMPYVHVMHQRGLNVYDILRYRSLAMTPDALRELVRRLDAPLKPGRMTREDRLVVDEDADPLAPPAPEARDPGVELPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N103</accession>
    <name>C1N103_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51212</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061487.1">
        <property type="nucleotide sequence ID" value="XM_003061441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N103"/>
    <dbReference type="GeneID" id="9686927"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51212"/>
    <dbReference type="OrthoDB" id="496430at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="330" mass="35947" checksum="6CF8FD39509BBE7C" modified="2009-05-26" version="1">MATSLAAAAASVAPRATARPARPRAAARGVRGGSRSVVVRGKKGAWAKEFDPDYEKDKEVVEITAEAEGWPGLAKDTEVETYNILTKLTGPLNITWNGIGVIQVPKGATRRRAKPFRLRVDLHHLLICLVVRVELYRPRARLATDHDGAGAAASVAPRATARPARPRAAARGVRGGSRSVVVRGKKGAWAKEFDPDYEKDKEVVEITAEAEGWPGLAKDTEVETYNILTKLTGPLNITWNGIGVIQVPKGADKKESGNVCKTVLVQRKEQVLAECDRLYPKMKGKPKDYVIQLFEDPYADPVDLSAVPPAGLEPVPAEIKYMPKGKRYPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N200</accession>
    <name>C1N200_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_51794</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062206.1">
        <property type="nucleotide sequence ID" value="XM_003062160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N200"/>
    <dbReference type="GeneID" id="9687443"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51794"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MIGCTTA"/>
    <dbReference type="OrthoDB" id="10261634at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="9"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="361" mass="37271" checksum="930BD9AA913D949E" modified="2009-05-26" version="1">MAAVAETARLAATIVLYVALNSSLNLLNRYTLGHAGFRYPVLLTCAHLAFQTLALAPVVLGGGASPKGGKASSWSNALASHEETVMKHWRGIAAIGVLMAANVALNNASLLHLQISYNQVIRASTPVVCAACAVFVEGVVPKPSEALGLVLVTAGVMSTVGASSGAGGGGDAGSQKTGHETLGVAFAASATLANALLMTLSGKLMGGDRIDALKLTFYVSPVVLLALLPVGMHAEWDSMTEKYAIASVSATEPDFVAGEPLTRLILLGCVIAVCYNWVHNKIISVTSATTTTVLGNVKVVTIMLSSRMLFGETKDWTLGMVAGAGVALFGFALYSAAKLRTKLEKEKAEDARGGATQRGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2J5</accession>
    <name>C1N2J5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_41830</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061885.1">
        <property type="nucleotide sequence ID" value="XM_003061839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2J5"/>
    <dbReference type="GeneID" id="9687325"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41830"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="401"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="800"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="871" mass="90361" checksum="B8DB165B61E5D32F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2S5</accession>
    <name>C1N2S5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_21119</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062135.1">
        <property type="nucleotide sequence ID" value="XM_003062089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2S5"/>
    <dbReference type="STRING" id="564608.C1N2S5"/>
    <dbReference type="GeneID" id="9687368"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21119"/>
    <dbReference type="eggNOG" id="KOG1113">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WSPPHHP"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000006">
        <property type="entry name" value="cAMP-dependent protein kinase type I-alpha regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0114">cAMP</keyword>
    <keyword evidence="3 7" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="56"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="181"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000548-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH53847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="314" mass="33820" checksum="97B27AEA49E15145" modified="2009-05-26" version="1">MNASCVRPSFVSHSDRGGGARRSSRGEPEPPSPNSRAAKTAAQRDEVRARVRDNILFKDLDAAPLEELVDAAFEVSYPAGAVVIEQGDEGDNFYVVADGVADAAVRGKIAGDAPTTVQVLEPGASFGELSLMYNSPRAATVTARTACRLWALDRETFRDIACVSSQRTRKTREGFLERVPVLSALTAAERSRVADAIETKSFARGDAVVSQGEDGDAFYIVERGQAAAAREGVDARERDVEVKRYVPGDYFGELALLTEKRRAATVRAVSDVLVCAVVSRATFTRLMGSCETIMKRNIESYKEIMMTLGGVGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2S6</accession>
    <name>C1N2S6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Inner dynein arm heavy chain 1-alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">IA1-DHC1A</name>
        <name evidence="19" type="ORF">MICPUCDRAFT_35522</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061928.1">
        <property type="nucleotide sequence ID" value="XM_003061882.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N2S6"/>
    <dbReference type="GeneID" id="9687575"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35522"/>
    <dbReference type="eggNOG" id="KOG3595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VGEAMYG"/>
    <dbReference type="OrthoDB" id="64868at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000153">
        <property type="entry name" value="Dynein axonemal heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000005">
        <property type="entry name" value="Dynein axonemal heavy chain 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000005">
        <property type="entry name" value="Dynein axonemal heavy chain 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000007">
        <property type="entry name" value="Dynein axonemal heavy chain 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000006">
        <property type="entry name" value="Dynein axonemal heavy chain 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000008">
        <property type="entry name" value="Dynein heavy chain 10, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000002">
        <property type="entry name" value="dynein heavy chain 17, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000001">
        <property type="entry name" value="dynein heavy chain 17, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000063">
        <property type="entry name" value="dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000049">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF63">
        <property type="entry name" value="DYNEIN AXONEMAL HEAVY CHAIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="11 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="1968"/>
            <end position="2106"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="2252"/>
            <end position="2402"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="2606"/>
            <end position="2969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="61"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="3958"/>
            <end position="4023"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="501"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="3266"/>
            <end position="3297"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="3431"/>
            <end position="3500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="3994"/>
            <end position="4023"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH53640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="4697" mass="529942" checksum="D64B9FC05FAE7BA1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N317</accession>
    <name>C1N317_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">F-ATPase gamma subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ATPC</name>
        <name evidence="11" type="ORF">MICPUCDRAFT_48500</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast thylakoid membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062301.1">
        <property type="nucleotide sequence ID" value="XM_003062255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N317"/>
    <dbReference type="STRING" id="564608.C1N317"/>
    <dbReference type="GeneID" id="9687972"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48500"/>
    <dbReference type="eggNOG" id="KOG1531">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VMQFEQD"/>
    <dbReference type="OrthoDB" id="239812at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1380.10:FF:000006">
        <property type="entry name" value="ATP synthase gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.80:FF:000003">
        <property type="entry name" value="ATP synthase gamma chain, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.80:FF:000004">
        <property type="entry name" value="ATP synthase gamma chain, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.80">
        <property type="entry name" value="ATP synthase, gamma subunit, helix hairpin domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004145">
        <property type="entry name" value="PRK05621.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="ATP SYNTHASE GAMMA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693:SF41">
        <property type="entry name" value="ATP SYNTHASE GAMMA CHAIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="ATP synthase (F1-ATPase), gamma subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="8" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="365" mass="39453" checksum="016EE2015CC62950" modified="2009-05-26" version="1">MAVKPTVATPLASKKSAFAGRGVAAVAPKTATGGRASLQVLAASQKEMRDRISSVNSTKKITEAMKLVAAAKVRRAQDAVINARPFSESLVKVLFAINTRLAGEDVDVPLCDVRPVKTVLLLVCTGDRGLCGGFNNFIIKKAEERVAELKTQGVAAKLVTIGKKGSVYFKRRKDQYDLVKTFDMGQAPKTEEAQAIADEVYSEFVGEEVDKVELVYSRFVSLINSDPSIQTLLPLSKEGEICDVNGTCVDAQNDIIFSLTTEDGKFAVKGEPVETEVAGFEGVMQFEQDPNQILDALLPLYMNSQILRALQESLASELAARMNAMSNASDNAKDLSKRLTLEYNRKRQAKITAEIIELVAGASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N365</accession>
    <name>C1N365_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52054</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062327.1">
        <property type="nucleotide sequence ID" value="XM_003062281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N365"/>
    <dbReference type="STRING" id="564608.C1N365"/>
    <dbReference type="GeneID" id="9687767"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52054"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="180"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="243" mass="24841" checksum="3F7D40490626C274" modified="2009-05-26" version="1">MAVLNDDDYLDVETIIAGRDKATESAAKKYRERAAAAAAAAANAAERAYKDATRAEKEREPLVRVVPGPPIGDLAGDGPAAMAGMARSSSSATATANATTAERIETPPGRFPPTFLIAGCADVTVPWFESAEFHWALHDADVPSRVLLYLKENHVGFVLDWRPKPGASIRDEKADRDGDAAAAGASASASAPAAGETAPVALSAVGMGERASGGASGGGNGVAGGGIDDLGDHHRDILRLVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1N376</accession>
    <name>C1N376_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_48526</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062559.1">
        <property type="nucleotide sequence ID" value="XM_003062513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N376"/>
    <dbReference type="STRING" id="564608.C1N376"/>
    <dbReference type="GeneID" id="9687999"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48526"/>
    <dbReference type="eggNOG" id="KOG2012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.180">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, FCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12550">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2660">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, SCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.60">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, UFD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042302">
        <property type="entry name" value="E1_FCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018965">
        <property type="entry name" value="Ub-activating_enz_E1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038252">
        <property type="entry name" value="UBA_E1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042063">
        <property type="entry name" value="Ubi_acti_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF29">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09358">
        <property type="entry name" value="E1_UFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00985">
        <property type="entry name" value="UBA_e1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-activating enzyme E1 C-terminal" evidence="5">
        <location>
            <begin position="971"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="819"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="822"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1149" mass="121937" checksum="61AAA4B9050B6EA1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3D7</accession>
    <name>C1N3D7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_68616</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062592.1">
        <property type="nucleotide sequence ID" value="XM_003062546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3D7"/>
    <dbReference type="STRING" id="564608.C1N3D7"/>
    <dbReference type="GeneID" id="9687801"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68616"/>
    <dbReference type="eggNOG" id="ENOG502R7NG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052390">
        <property type="entry name" value="tRNA_nt/polyA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47788:SF1">
        <property type="entry name" value="A-ADDING TRNA NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47788">
        <property type="entry name" value="POLYA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="416"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="608" mass="64794" checksum="2B5F1805F59D1F59" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3X6</accession>
    <name>C1N3X6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_68764</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062691.1">
        <property type="nucleotide sequence ID" value="XM_003062645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3X6"/>
    <dbReference type="GeneID" id="9687891"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68764"/>
    <dbReference type="eggNOG" id="ENOG502S1TJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PGDWQVF"/>
    <dbReference type="OrthoDB" id="8026949at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053021">
        <property type="entry name" value="Chloroplast_ADK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35509">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (DUF1995)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35509:SF4">
        <property type="entry name" value="DUF1995 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1995" evidence="2">
        <location>
            <begin position="50"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="305" mass="33368" checksum="FEDCC287F4E7416F" modified="2009-05-26" version="1">MMASAVHRHSVVSSRRGGARLGSRARAPRAAKRASVARAAFEVGEGPRLPRSPREQAKQAAEAVARAAASGKKFFSIEFSLPLIGATDLDDWPGGVRQQYQAVAPMVGEFLKRVGGDDNADVKQQVIDDSDAVVVLKTPAAKAMVFLTAETLPELKKLAAAEEKTGGTLAIVNSQIMNGEGSNLISDLGIGPWKKKNEDFLATFEQAYWISEQRIQGETIRLLKSYPYPWSLYVLTDMNANDTEPKFIQTFDEKPSYKELEAILMKREGSVAAMSIIDRVKREATFNATSVSQKPNNQSMDEGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N449</accession>
    <name>C1N449_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_4239</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062484.1">
        <property type="nucleotide sequence ID" value="XM_003062438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N449"/>
    <dbReference type="STRING" id="564608.C1N449"/>
    <dbReference type="GeneID" id="9687924"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4239"/>
    <dbReference type="eggNOG" id="KOG2153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="496971at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="2">
        <location>
            <begin position="98"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="292" mass="31234" checksum="62FD801027F6EA7F" modified="2009-05-26" version="1" fragment="single">EKSLERDMSEAAGRMDNAAKRKLQSKMLLATFEMYFRVLKNAASPVPAKRLPLMTPALIGLGKFTHLISVNFMEDLMEVFRKLLAGDALSADQKARTLLCACEILSGHGEALHVDTGEFHRQLYAMLAKPSDWTGGGDDDAKLDAGALRIKTLQRFLAGYKQVDQNRVAAFAKRLAGTALASEAGEAVGALGVARQLLAAYPKTRCLLENEKVGVGAFDPNLDDPETCVGLAAVLWDLSLLRSHYHPAVAAAASEVAGMPLQGAVATALGSHAPAELARLHSTTRGTFRPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N477</accession>
    <name>C1N477_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52441</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062743.1">
        <property type="nucleotide sequence ID" value="XM_003062697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N477"/>
    <dbReference type="GeneID" id="9687940"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52441"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF116">
        <property type="entry name" value="F21J9.27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="628" mass="66602" checksum="71BC5AE50A9E881C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N493</accession>
    <name>C1N493_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52465</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062750.1">
        <property type="nucleotide sequence ID" value="XM_003062704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N493"/>
    <dbReference type="GeneID" id="9688399"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52465"/>
    <dbReference type="OMA" id="NENEEEX"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="225" mass="25311" checksum="0EAF4C94B0287EF7" modified="2009-05-26" version="1">MGLFGKLARKKTTTKTKKESSAQRAHREEMRAQREAYDAMAARIAAEARALYARKDACLRCNDAFDALESDESEDDTSDEESDEDEDVDVDSDDVSSEEDDTSDEDAYDSDDDGGGRRLKKKTAKDDDDDDDDDDDDDDDAASEDDADEPERDDTRRAFAAAMTLVDVYRAEPIWCFPPPKRAKKEERDAIYVVESGEVDVEVERKARSIHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4C1</accession>
    <name>C1N4C1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mastigoneme-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_71069</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062974.1">
        <property type="nucleotide sequence ID" value="XM_003062928.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N4C1"/>
    <dbReference type="GeneID" id="9688203"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_71069"/>
    <dbReference type="eggNOG" id="KOG0941">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAERSHH"/>
    <dbReference type="OrthoDB" id="527488at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00185">
        <property type="entry name" value="TNFRSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006212">
        <property type="entry name" value="Furin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001368">
        <property type="entry name" value="TNFR/NGFR_Cys_rich_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN,N-TERMINAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967:SF1">
        <property type="entry name" value="KERATIN-ASSOCIATED PROTEIN 16-1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00261">
        <property type="entry name" value="FU"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00208">
        <property type="entry name" value="TNFR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910752" evidence="3">
        <location>
            <begin position="28"/>
            <end position="3898"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="2388"/>
            <end position="2441"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="2446"/>
            <end position="2495"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="2496"/>
            <end position="2568"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="2741"/>
            <end position="2802"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="2803"/>
            <end position="2854"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="4">
        <location>
            <begin position="3115"/>
            <end position="3146"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="4">
        <location>
            <begin position="3169"/>
            <end position="3200"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="4">
        <location>
            <begin position="3240"/>
            <end position="3271"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="4">
        <location>
            <begin position="3417"/>
            <end position="3448"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="4">
        <location>
            <begin position="3451"/>
            <end position="3485"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="4">
        <location>
            <begin position="3670"/>
            <end position="3706"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="4">
        <location>
            <begin position="3723"/>
            <end position="3757"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="4">
        <location>
            <begin position="3777"/>
            <end position="3811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="646"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="715"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="884"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="944"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2589"/>
            <end position="2619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="658"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="948"/>
            <end position="960"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="3898" mass="402862" checksum="BA8980A44F7A87D6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5X0</accession>
    <name>C1N5X0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_36328</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063230.1">
        <property type="nucleotide sequence ID" value="XM_003063184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5X0"/>
    <dbReference type="STRING" id="564608.C1N5X0"/>
    <dbReference type="GeneID" id="9688670"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36328"/>
    <dbReference type="eggNOG" id="KOG2150">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CECKIES"/>
    <dbReference type="OrthoDB" id="293823at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012270">
        <property type="entry name" value="CCR4-NOT_su3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007207">
        <property type="entry name" value="Not_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04065">
        <property type="entry name" value="Not3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005290">
        <property type="entry name" value="NOT_su_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-Not complex component Not N-terminal" evidence="10">
        <location>
            <begin position="4"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="271"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH52366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="360" mass="39568" checksum="F7A253E23A0C41A8" modified="2009-05-26" version="1" fragment="single">MADRRKLQAEIDRTLKKIEEGVEVFDRIFDKVTEAENQSLKEKHEARPPSRALLRSAELKKEIKKLQRFRDQVKQWAGSNDVKDKNPLLEARRTIEREMERFKVVEKETKTKAFSKEGLARAASSKDPKEKAREDARDWLNRATDGLNEQMEAFEAEVETISSEKKGKKSAKSNPRLGHLEESIQRHLQHVARLELVLRLIDNEALAPEDAEDLKDLIEDYLERNQDDFDEFADPEEMYEDLNLDELDEIKQMAHEVAHSAPTVVEKVIEKVEAAESKKEGGDAGGGGGGGGDSNANATAAAAASAKTAAKPPKTPEKTLPTPVLGGDKKLPAPLGLSTAGPQSQGGGGEGGAVKVLPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6H9</accession>
    <name>C1N6H9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48886</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063535.1">
        <property type="nucleotide sequence ID" value="XM_003063489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6H9"/>
    <dbReference type="GeneID" id="9688974"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48886"/>
    <dbReference type="OMA" id="AERNCEC"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910766" evidence="2">
        <location>
            <begin position="17"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="530"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="595" mass="60073" checksum="F79E881EB6791A1F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6R3</accession>
    <name>C1N6R3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_9123</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063596.1">
        <property type="nucleotide sequence ID" value="XM_003063550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6R3"/>
    <dbReference type="STRING" id="564608.C1N6R3"/>
    <dbReference type="GeneID" id="9689037"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9123"/>
    <dbReference type="eggNOG" id="KOG1698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TITVYYE"/>
    <dbReference type="OrthoDB" id="432645at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_bL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="Ribosomal_bL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680:SF9">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="113" mass="12735" checksum="93A10A1DF9039FFD" modified="2009-05-26" version="1" fragment="single">FVERVNAPQMKDDLIPFRVGMTCKVGVTVVEGGKSRVQPYEGIIIAIHRAGVATTITVRKSFQGYGVERIFPIHSPLCTFEEIRGAGKPKVRRAKLYYLRNLVGKQAKLKMRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6X7</accession>
    <name>C1N6X7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_29887</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063808.1">
        <property type="nucleotide sequence ID" value="XM_003063762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6X7"/>
    <dbReference type="STRING" id="564608.C1N6X7"/>
    <dbReference type="GeneID" id="9689072"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29887"/>
    <dbReference type="eggNOG" id="KOG0043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6360546at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.170">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006602">
        <property type="entry name" value="DM10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040193">
        <property type="entry name" value="EFHC1/EFHC2/EFHB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086">
        <property type="entry name" value="EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086:SF9">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06565">
        <property type="entry name" value="DM10_dom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00676">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51336">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DM10" evidence="8">
        <location>
            <begin position="109"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="DM10" evidence="8">
        <location>
            <begin position="294"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="DM10" evidence="8">
        <location>
            <begin position="479"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="46"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="628" mass="69152" checksum="B9CE68C7C6962AD0" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7H9</accession>
    <name>C1N7H9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial fission process protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial 18 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_22869</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063902.1">
        <property type="nucleotide sequence ID" value="XM_003063856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7H9"/>
    <dbReference type="GeneID" id="9689343"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22869"/>
    <dbReference type="eggNOG" id="KOG3945">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AINRICY"/>
    <dbReference type="OrthoDB" id="424969at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019560">
        <property type="entry name" value="Mitochondrial_18_kDa_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001:SF2">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10558">
        <property type="entry name" value="MTP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="206" mass="21629" checksum="27CE3678F9A5AC06" modified="2009-05-26" version="1">MTVVANSGEKDPNAPYDIYRDSPLRYMGYANEVGEAFAAFVGETGVVASYGVAALYVFADTFDKGKKAYEGEADEDQKVKRGAIVTLDTLTWQLLASVFWPGSFIRVMVNTTTVALSLAHLDGIEVNGFDVSKAIPTIVGLGTIPFIVKPIDGTIDTAMEMSVTKALNGKIEGVQDAGVALATISACLVVPPTLFSVAAAIKAIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7S2</accession>
    <name>C1N7S2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_43164</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063957.1">
        <property type="nucleotide sequence ID" value="XM_003063911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7S2"/>
    <dbReference type="GeneID" id="9689584"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43164"/>
    <dbReference type="OMA" id="ICLWENA"/>
    <dbReference type="OrthoDB" id="496634at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="19945" checksum="E29130FB75316F8E" modified="2009-05-26" version="1">MLAIVYVSAFVVAAWAPFAYHHRAVHGVVNPTHLALTLFNAINLLICLWENALYLHVKKIRKKYLAMKRTLGHGTFPPKLCLFEDVSLRDALTYEHWGIVWATYSLLDPSYSDQMLYGTVLYFGNYLKNQYYRGTSAAYVGLVVAMNAIWIVFPAAWMWMCWGMIRTGSLDALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Z8</accession>
    <name>C1N7Z8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_49091</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063993.1">
        <property type="nucleotide sequence ID" value="XM_003063947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Z8"/>
    <dbReference type="STRING" id="564608.C1N7Z8"/>
    <dbReference type="GeneID" id="9689624"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49091"/>
    <dbReference type="OMA" id="NEQHTHA"/>
    <dbReference type="OrthoDB" id="1932806at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="200"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="391"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="54"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="281"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="581"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="635"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="137"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="312"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="581"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="608"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="635"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="717"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="734"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="771"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="786"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1016" mass="111508" checksum="43773B0B16E90116" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N802</accession>
    <name>C1N802_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53894</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064184.1">
        <property type="nucleotide sequence ID" value="XM_003064138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N802"/>
    <dbReference type="STRING" id="564608.C1N802"/>
    <dbReference type="GeneID" id="9689437"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53894"/>
    <dbReference type="eggNOG" id="ENOG502S19X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FLFTWPD"/>
    <dbReference type="OrthoDB" id="25620at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="370" mass="39147" checksum="83D7242CB319850F" modified="2009-05-26" version="1">MTSSLASRAPAATPTPSPRAHRARPRVASLPRAAAAAVRVPRFPSSRRRGSSRRDRRAVVLVPRASNDDGDGAAPKEELDFVTRVVMNVFGKDVLDDPAPAGLKRMTKEDWPDQWPALCDQGVVAAILPTDDTDELKLARAVLKQSQLETLPLGCAFDADVHGWRSAAFHLQLDGQGAAVLVAVAEDGTVFGAYNPKGWLGYGEWLDAISAFLFVYPRVGPLGLGGSGGTPVKLGKVGGSGMAIIDEMNASPKWGPDGLAFNIDQRVARSRLGTYYDTMPNGSKSLFGGGVSKGGGTVGLKSLRVYVGLGESDLARDYEPNMFQWKKGELEEVRKNDPKPTGSVDEGDGGGRGGGGTGGMFGGIKMPWDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8B4</accession>
    <name>C1N8B4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_7426</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064052.1">
        <property type="nucleotide sequence ID" value="XM_003064006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8B4"/>
    <dbReference type="STRING" id="564608.C1N8B4"/>
    <dbReference type="GeneID" id="9689681"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7426"/>
    <dbReference type="eggNOG" id="KOG3420">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DVVYSIH"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008988">
        <property type="term" value="F:rRNA (adenine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051720">
        <property type="entry name" value="rRNA_MeTrfase/Polyamine_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23290">
        <property type="entry name" value="RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23290:SF0">
        <property type="entry name" value="RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="218" mass="23796" checksum="00365672AC3BE103" modified="2009-05-26" version="1" fragment="single">MKLKHLESLLQDIEPFRDPNVHLEQYPTGAHLAACVLHAAAERDDVDGRVVVDLGVGGGVLGIAASMMGAKRVVGVDVDPAAIELARENCDAFDPPIEIELRLGKTATPSSSDASDPNRALRADTVVMNPPFGTRRKGADMGFLRAALGVTRRGGAVYSLHKSSTRAHVERHALVVLRAKSAEVLAELRYELPRVYSHHRRDAVDIEVDLWRFEPPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8K7</accession>
    <name>C1N8K7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_43350</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064283.1">
        <property type="nucleotide sequence ID" value="XM_003064237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8K7"/>
    <dbReference type="GeneID" id="9689543"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43350"/>
    <dbReference type="eggNOG" id="ENOG502SYQH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317">
        <property type="entry name" value="BLR8090 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317:SF1">
        <property type="entry name" value="ZINC-RIBBON DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="25"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="101"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="177"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="254"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="330"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="407"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="473" mass="53571" checksum="E52635AEECE194F1" modified="2009-05-26" version="1">MTPHEERPGSLVKWCGENGERGQRLLLEYRDDEKLPSEVMALSSYNALWRCAECEHEWKAGVCSRTRSDAAAECMRCRGCSARGISFRVWCDANGERGKSLLEEYVDTDRGPMDVTRASGYKALWKCATCEHEWRTKICNRTTANNPTGCPKCPGFVARSNKFQVWCDANGERGKKLLEEYVDTDRGPTDVTHGSKYKALWKCATCEHEWRAKMNNRMRANNPSGCPACSGYTATSTKNFQVWCEENGERGKKLLEEYVDTDRGPTDVTHGSSYKALWKCATCEHEWWATMNHHTRANNPAGCPSCSRYAARSTFRVWCDANGEIGKKFLEEYVNTDRGPMDVTRASAYKALWKCATCEHEWRAKVGSRTNSRRPCGCPKCANHLPLSKTNNFQAWCDANGERGKTLLEEYIDPDRGPTRVTNGSTYKALWKCATCEHEWRTTLNCRTLSGRPTGCPANCRKKRKRHSPATTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N962</accession>
    <name>C1N962_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54376</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064563.1">
        <property type="nucleotide sequence ID" value="XM_003064517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N962"/>
    <dbReference type="GeneID" id="9690004"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54376"/>
    <dbReference type="OMA" id="FREWREM"/>
    <dbReference type="OrthoDB" id="498000at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="54"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="274" mass="30433" checksum="6A4306344EE9AFD7" modified="2009-05-26" version="1">MTPPPIFEPAGDWFDPEIRRFVRIDAADPPPKRAALFVGSSIFREWREIRDFDADFAPTRVINRAFGGSTTEDLLRVVDAIATPHDPEIIVYYCGSNDVNEGRGAAAIRDAFAAFCDRGETASHTTPFAWCTPFLKDFSRRHSSPALPFQRLTVGPRVERILFVSVCKAPQKMPVWDEVDAVNDAMRAHCAANAPRLTYVEVNPGLFEEGSSSPGSPPRPRFNLYREDGLHFVDRAYDDVLLPVIKAALERALGEVKAARGEGEAAHLPPGMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9H0</accession>
    <name>C1N9H0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54501</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064452.1">
        <property type="nucleotide sequence ID" value="XM_003064406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9H0"/>
    <dbReference type="STRING" id="564608.C1N9H0"/>
    <dbReference type="GeneID" id="9689893"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54501"/>
    <dbReference type="OMA" id="ANTRHEY"/>
    <dbReference type="OrthoDB" id="546434at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47852">
        <property type="entry name" value="OS06G0298400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47852:SF2">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="123"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="565"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="529"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="601" mass="61707" checksum="81AE1D29733EFF5A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9L4</accession>
    <name>C1N9L4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54174</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064474.1">
        <property type="nucleotide sequence ID" value="XM_003064428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9L4"/>
    <dbReference type="GeneID" id="9689915"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54174"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="325" mass="35491" checksum="884097AC7DEE3D4F" modified="2009-05-26" version="1">MASMPRVRSGGGRAMKIVTTLRWSQYVQSRINLSESIKPVGEKIWSLCSVCLLFPSFHVRVEGRPRFRGGAVFAARADPARVWLRDGTLRGTFTQRARIDDDGASVTTKARDGARSQHQSGLTLPPTINLRAEMPRRDADAEPASADADDVDGAMEDHTTEPTDEREILSWFLYDCGSSPIGVTAISFWSLLITLLAKEQAAGNAEGIAWRKVHAAGDVCEGVCYGTAGCLRYDRDLYPSMEFERPDGMDSACEWFPVNGDVGPNDVDYGTVVVFCNVSAQLACGLILVFFGTLGDFGSFRYKGLGAFESHWSPYDRVGVANADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAG9</accession>
    <name>C1NAG9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66071</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064907.1">
        <property type="nucleotide sequence ID" value="XM_003064861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAG9"/>
    <dbReference type="GeneID" id="9690347"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66071"/>
    <dbReference type="OrthoDB" id="503245at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="393" mass="44649" checksum="2DE17A78CE6749B4" modified="2009-05-26" version="1">MANENRQGCRGRRKKRTRNVRTILYTLLTCALGWFLTYVSSHASERGFRARKLPRGKCKTFVFSETARGNSALFFRHGTLKCTGEKFGRLGNRLMIITNMINFAEKNCCNVLVDEDVVPGWNPAPLFLRQVSLCDLAHTEKMTCTPKSRFDWFFQGLDPPNFLPVQLGDCALQSLKTYFKIDERSALGEQCPTSPHAVLHVRAGDIVAGTYDSISGTYHPSPGVHPDYWVYPTSYYTSAIREIRRQSDKKIYVICENMDNPSCEFFAKISGVYTNIEFRVGRALLDDLHILLCASEVATSFGSFQLIFGLSEKIEKLHTFVLEEPPDKKCLTHLSSSFYSNLFVPQAVFHWITDSAERKSFSQAVKPWHNTALQRHIIDANRSITTCSSRILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAM8</accession>
    <name>C1NAM8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_23888</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663755">
        <property type="protein sequence ID" value="EEH50842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAM8"/>
    <dbReference type="eggNOG" id="ENOG502R8RC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2020507at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH50842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="55" mass="6374" checksum="E17C73B9CD081C4B" modified="2009-05-26" version="1" fragment="single">QVLDCSPTNRERELGLDRRETVIQPSTRGTVDSHNWSSRLVEKPVARSYRALDYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGI8</accession>
    <name>C1MGI8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_61058</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054782.1">
        <property type="nucleotide sequence ID" value="XM_003054736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGI8"/>
    <dbReference type="STRING" id="564608.C1MGI8"/>
    <dbReference type="GeneID" id="9680582"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61058"/>
    <dbReference type="eggNOG" id="ENOG502RXQF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="549476at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05162">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047365">
        <property type="entry name" value="Tudor_AtPTM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21743">
        <property type="entry name" value="PTM_DIR17_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="4">
        <location>
            <begin position="210"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="318"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="384"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="430"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="746" mass="76504" checksum="5E33D4DB27F75699" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGS8</accession>
    <name>C1MGS8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein YUH87</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">YUH87</name>
        <name evidence="10" type="ORF">MICPUCDRAFT_70659</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054828.1">
        <property type="nucleotide sequence ID" value="XM_003054782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGS8"/>
    <dbReference type="STRING" id="564608.C1MGS8"/>
    <dbReference type="GeneID" id="9680802"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70659"/>
    <dbReference type="eggNOG" id="ENOG502RZTC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MCALLHE"/>
    <dbReference type="OrthoDB" id="1368at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="378"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="454" mass="50492" checksum="946F2CAE645C0C89" modified="2009-05-26" version="1">MSAVTARLPAGGRARARIPARRRDRAPATVATATRGGGGFSRKKVHIIPPTLRTLDALRPRRRGDAVIARDADADGGGGGSPPVNELPMVKQQASGLGLQCMPKARMNDEVARIDPGLNQLLVSEGSTISRFFTQDEWERHRGVGRYWRHLFSTCKSTIFLRILETVIWITLSAAALCAYNLVLVPKFSLPTLTIPPIVHQLSGSVLSLSLVFRTNNANRRVIDARSILGKISKCTRDLTRMCMYIPNEGGCRFEILNQLRAFPYAFEAHVRKGRTRKSKKDPTAFKSEPLPLLTRALGERDARRLLERSHENVARQVLLDMSTILQRALTIGMSTQMHQQCEIICKELSDCLANAEKILYTPIPIAYTRHTSRSLTIWLLTLPLALWSLMGMSMIPSVFLIAYLMLGVDEIGIEIEEPFCVLPVRPIAEMCDSEIVNSFDQALAAPDFKPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGU1</accession>
    <name>C1MGU1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein kinase ATM</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_30638</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054836.1">
        <property type="nucleotide sequence ID" value="XM_003054790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGU1"/>
    <dbReference type="STRING" id="564608.C1MGU1"/>
    <dbReference type="GeneID" id="9681084"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30638"/>
    <dbReference type="eggNOG" id="KOG0892">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SETRIRC"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05171">
        <property type="entry name" value="PIKKc_ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000023">
        <property type="entry name" value="Serine/threonine-protein kinase ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038980">
        <property type="entry name" value="ATM_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044107">
        <property type="entry name" value="PIKKc_ATM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="15">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="14">
        <location>
            <begin position="190"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="16">
        <location>
            <begin position="508"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH60088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="540" mass="60015" checksum="DB341F5D3EB8E633" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGU3</accession>
    <name>C1MGU3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-intron lyase</fullName>
            <ecNumber evidence="2">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SEN2</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_70667</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.</text>
            <dbReference type="EC" id="4.6.1.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055379.1">
        <property type="nucleotide sequence ID" value="XM_003055333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGU3"/>
    <dbReference type="STRING" id="564608.C1MGU3"/>
    <dbReference type="GeneID" id="9681243"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70667"/>
    <dbReference type="eggNOG" id="KOG4685">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CCEDAYY"/>
    <dbReference type="OrthoDB" id="10249562at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000214">
        <property type="term" value="C:tRNA-intron endonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006676">
        <property type="entry name" value="tRNA_splic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="5">
        <location>
            <begin position="186"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="311" mass="33788" checksum="44F4D515F6A846D6" modified="2009-05-26" version="1">MPPVADTRVHFKRGKRRAAAKQPSPAECLRVLSACDLHGVLHRGAVWLRCARKLAYLLERVCLGRRARGSSGRGAPCFFRNVVGDERGGDSADDDPIVRLSPEEAFYVVWCLGSLTVHAPRDAADDAADGAENQIQNPERNAPPPPSLTPLTIDELWRALLTAGMSGVNAAIAAPRFVAAAASQIHFRSAGWLPRSGLQYGADLVLYRNHPSLVHSDCCVVVKPSSAIVSRASGVFGEGGELEKDSRWIEVQAASRLCVQVNKRLVFATLDVAGGDADFLDPECLKRLSVNEMEVTRFNPDRHLTRGERPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHP0</accession>
    <name>C1MHP0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_37930</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055525.1">
        <property type="nucleotide sequence ID" value="XM_003055479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHP0"/>
    <dbReference type="STRING" id="564608.C1MHP0"/>
    <dbReference type="GeneID" id="9680840"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37930"/>
    <dbReference type="eggNOG" id="ENOG502QUUE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TPMLIHA"/>
    <dbReference type="OrthoDB" id="414267at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02516">
        <property type="entry name" value="CDP-ME_synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000003">
        <property type="entry name" value="2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001228">
        <property type="entry name" value="IspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050088">
        <property type="entry name" value="IspD/TarI_cytidylyltransf_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00453">
        <property type="entry name" value="ispD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32125">
        <property type="entry name" value="2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32125:SF4">
        <property type="entry name" value="2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00069967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="205" mass="22902" checksum="7C3BC03BA8D37A49" modified="2009-05-26" version="1">MPKQYLPLLGTPIALYSLKKFAEMDEVGEIVVVCDPSYRDVFEECAVSKPVKFALPGKERQDSVFNGLSEVRDGAALAAIHDSARPLVSLDDARRCFQDAMEHGAAVLAVKCKATVKEANDDLSIAKTLDRSKLWEMQTPQVIKPEILKEGFKLVNEKGYEVTDDVSIVEFMGRRVQITEGSYVNIKVTTPEDMFIAERLMNEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHX1</accession>
    <name>C1MHX1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_50352</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055566.1">
        <property type="nucleotide sequence ID" value="XM_003055520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHX1"/>
    <dbReference type="STRING" id="564608.C1MHX1"/>
    <dbReference type="GeneID" id="9681133"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50352"/>
    <dbReference type="OrthoDB" id="19714at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039924">
        <property type="entry name" value="ICln/Lot5/Saf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399">
        <property type="entry name" value="CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399:SF0">
        <property type="entry name" value="METHYLOSOME SUBUNIT PICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03517">
        <property type="entry name" value="Voldacs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="162" mass="16411" checksum="4CC02AB1F3908E7C" modified="2009-05-26" version="1">MHAVSRGGGDGGFDRPCIYAQVEGAPPDGVKTGGEEKEKEEEEEEEDGGGGGGVGVDDFDEMTELRLVPTDPSALDDVFNTMSECAAMNPDDDDDDDDDGGGGGGGGGFYYDEAAVANGAGAAERAAALARLDALLVTDGDAGDAVDAAIANDPGRFEDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHY1</accession>
    <name>C1MHY1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_50363</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055036.1">
        <property type="nucleotide sequence ID" value="XM_003054990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHY1"/>
    <dbReference type="STRING" id="564608.C1MHY1"/>
    <dbReference type="GeneID" id="9680425"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50363"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CVISAPP"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46151">
        <property type="entry name" value="NEP1-INTERACTING PROTEIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46151:SF18">
        <property type="entry name" value="NEP1-INTERACTING PROTEIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="62"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="17894" checksum="B8D70B4907AF9E20" modified="2009-05-26" version="1">MTSLVAADVDAMTYEELLETFGPGVEGVAGAPAAAIDAVPTSTLAADYAWKDAISDVEASSCRVCLDEFRVGEKVKALPSCGHRFHAPCIDKWLLGRNACPMCRVGLPETLCAMATGVSASAASAAAAGSAAGSRGEEEDVVAAAVAPSSAGWFEWARPSVVAPSSWFGRGRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIR7</accession>
    <name>C1MIR7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-intron lyase</fullName>
            <ecNumber evidence="2">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_50670</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.</text>
            <dbReference type="EC" id="4.6.1.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055179.1">
        <property type="nucleotide sequence ID" value="XM_003055133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIR7"/>
    <dbReference type="STRING" id="564608.C1MIR7"/>
    <dbReference type="GeneID" id="9680907"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50670"/>
    <dbReference type="eggNOG" id="KOG4133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GWGVKPK"/>
    <dbReference type="OrthoDB" id="498344at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059049">
        <property type="entry name" value="TSEN34_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26577">
        <property type="entry name" value="TSEN34_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TSEN34 N-terminal" evidence="8">
        <location>
            <begin position="8"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="7">
        <location>
            <begin position="180"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="87"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF26577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="315" mass="33220" checksum="503BE952508F59E1" modified="2009-05-26" version="1">MATADGPIRVQVSDDDTGLVWSAEEYHRLRTRHRVVGALVGGLPGFRQQDSVHGLPARLSPEEVTLALHRGWVTLYVARDAVAAAATAAERAPPPPAAKRPTVANKGWGVKPKGGFHNQKRLKTTKSLASDADAGWERVLNTSFVEIPLRAPSDAPDDADAGPDASSPEWSYPRTDAQRRRFAVFSDLHARGLTMTAGVKFGSDYLAYPGEPMAYHACFTVKVCDGDERMRARELSAASRMSHAARKNLVLATATAAAAATAAATGATAGGGGGEVGDDASPPPPPPPPRVMKVSYVTVTPDIEQSKGGRVERGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIY2</accession>
    <name>C1MIY2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CCT-theta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_31125</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055741.1">
        <property type="nucleotide sequence ID" value="XM_003055695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIY2"/>
    <dbReference type="STRING" id="564608.C1MIY2"/>
    <dbReference type="GeneID" id="9680969"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31125"/>
    <dbReference type="eggNOG" id="KOG0362">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WGLKYAV"/>
    <dbReference type="OrthoDB" id="1748577at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03341">
        <property type="entry name" value="TCP1_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000008">
        <property type="entry name" value="T-complex protein 1 subunit theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012721">
        <property type="entry name" value="Chap_CCT_theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02346">
        <property type="entry name" value="chap_CCT_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="541" mass="58692" checksum="107580930D6A7739" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJF4</accession>
    <name>C1MJF4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nuclear nucleic acid-binding protein C1D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_8873</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer and homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the C1D family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055305.1">
        <property type="nucleotide sequence ID" value="XM_003055259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJF4"/>
    <dbReference type="STRING" id="564608.C1MJF4"/>
    <dbReference type="GeneID" id="9680526"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8873"/>
    <dbReference type="eggNOG" id="KOG4835">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1421013at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011082">
        <property type="entry name" value="Exosome-assoc_fac/DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341:SF3">
        <property type="entry name" value="NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341">
        <property type="entry name" value="SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="89" mass="10013" checksum="7F9BDFA47FAEB014" modified="2009-05-26" version="1" fragment="single">PDDIKEQLTKYEAAIAAVEEKLEPLLRVKKDDLDAALTPLERAKVHVALANATTTMFCMYLKAVGLDPAEHAAKYELERVELYRAKVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJU6</accession>
    <name>C1MJU6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_38373</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056273.1">
        <property type="nucleotide sequence ID" value="XM_003056227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJU6"/>
    <dbReference type="STRING" id="564608.C1MJU6"/>
    <dbReference type="GeneID" id="9681286"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38373"/>
    <dbReference type="eggNOG" id="KOG1558">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LKDDIWC"/>
    <dbReference type="OrthoDB" id="261960at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053000">
        <property type="entry name" value="WSS1-like_metalloprotease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622:SF1">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WLM" evidence="7">
        <location>
            <begin position="19"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="374"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="164"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="250"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="266"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="415" mass="44595" checksum="C7DC94F525BE5B8C" modified="2009-05-26" version="1">MPPPRRPARTPARTPASSSSSSSETHRVHEIATLGRADDATARRLLERCAWHVQPIMRARRWRVATLLEMKPEQRDRVGDNYNRGERVRIKLRNPASDTGWYDLGHVVLVMLHELVHNDIGPHNRAFFKLLDEITAECEDLTARGVGGTGVGFDAPGAKLGHRGGWGGLETRSAKDAAKDAAERRARASAVMGPPGGRRLGGGETTEEIRKPAAAAAAAAAAAERRARGEDFAQRWGLLDDVVVLSDDDDDDVVCGDAPPPPPPPRARKVLKDRRSPRRRGRTGTSANGVENGRGVARTCPCCAAALDALDARAADAHARTCEEMAEGAKGEGVKTEKKRDRGAAATGDDVIVIDDDDDDDDDGRRRGRGRAAAAAAWRCRACTLDNPADASNCRACETWRFSRGAPAASRPTIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK00</accession>
    <name>C1MK00_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_8681</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055906.1">
        <property type="nucleotide sequence ID" value="XM_003055860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK00"/>
    <dbReference type="STRING" id="564608.C1MK00"/>
    <dbReference type="GeneID" id="9681909"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8681"/>
    <dbReference type="eggNOG" id="KOG0731">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANFVEMF"/>
    <dbReference type="OrthoDB" id="534441at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF113">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE FTSH 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="95" mass="10118" checksum="B9EFAF0F7141FC8E" modified="2009-05-26" version="1" fragment="single">IPRGTLLAGAPGTGKSLLARAIAGESNVPFIQCSTANFVEMFVGVGAKRARELFQVARENQPCIIFIDEIDAVGKQRGGGGFPSNDEREQTINQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKJ3</accession>
    <name>C1MKJ3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">monogalactosyldiacylglycerol synthase</fullName>
            <ecNumber evidence="2">2.4.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_45255</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.46" evidence="2"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056007.1">
        <property type="nucleotide sequence ID" value="XM_003055961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKJ3"/>
    <dbReference type="STRING" id="564608.C1MKJ3"/>
    <dbReference type="GeneID" id="9681956"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45255"/>
    <dbReference type="eggNOG" id="ENOG502QPXV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IHPYWIN"/>
    <dbReference type="OrthoDB" id="200404at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046509">
        <property type="term" value="F:1,2-diacylglycerol 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009695">
        <property type="entry name" value="Diacylglyc_glucosyltr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050519">
        <property type="entry name" value="Glycosyltransf_28_UgtP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43025">
        <property type="entry name" value="MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43025:SF3">
        <property type="entry name" value="MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06925">
        <property type="entry name" value="MGDG_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Diacylglycerol glucosyltransferase N-terminal" evidence="7">
        <location>
            <begin position="132"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 28 C-terminal" evidence="6">
        <location>
            <begin position="331"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="499" mass="54128" checksum="DAD7AB3A04B4764C" modified="2009-05-26" version="1">MDSSSVCFFPGSSGVYSAGRVVNTQPSIVAYQHAYLVGAIAGRSLRARAKAREQLTHSATLLFGGNACFFGLEHGMFASDEVATVFTGNTGGTGSWSSSEGSLEFTREPAPVSSLAIKKHVMCLMSDTGGGHRASAQALKDGFEIMFGDSFAIHVVDLWSSSSPWPLCNMPKSYFFLVKNPWLWRLSFRCSEPEILHEALFTGYTALVGRRFAKAFHENEPSLIVSVHPLMQHVPLKVLARMKAESSFVAARVPFTTVVTDLTRCHRTWFHRHVDKCFVATQLVAAQAMSYGLVANQLACHGLPIRPAFNAESLPKVELRRLLQLDLTASTVMLVGGGEGMGKLEATAEALSQTLSPGHQIVVICGRNEKLARTLAARTWPLKMVIKGFVNNMSEYMSACDCIITKAGPGTIAEALICGLPILLNGFIPCQEEGNVSFVLENGVGAFSEDPVEISQIISRWFKSDGIELNSMSSKAKSLGRPEATFNIVRDLAGMSTTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKP1</accession>
    <name>C1MKP1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_38461</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056029.1">
        <property type="nucleotide sequence ID" value="XM_003055983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKP1"/>
    <dbReference type="GeneID" id="9681352"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38461"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="623"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="805"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="319"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="845"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="856" mass="94773" checksum="7C0A29BEB324BAA0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLE2</accession>
    <name>C1MLE2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Porphobilinogen deaminase, chloroplastic</fullName>
            <ecNumber evidence="7">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Hydroxymethylbilane synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">HEMC</name>
        <name evidence="17" type="ORF">MICPUCDRAFT_31842</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the HMBS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="7"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056550.1">
        <property type="nucleotide sequence ID" value="XM_003056504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLE2"/>
    <dbReference type="STRING" id="564608.C1MLE2"/>
    <dbReference type="GeneID" id="9681583"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31842"/>
    <dbReference type="eggNOG" id="KOG2892">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LWQANHI"/>
    <dbReference type="OrthoDB" id="564646at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13648">
        <property type="entry name" value="PBP2_PBGD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.40:FF:000001">
        <property type="entry name" value="Porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000004">
        <property type="entry name" value="Porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000101">
        <property type="entry name" value="Porphobilinogen deaminase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="entry name" value="Porphobilinogen deaminase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557:SF0">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobilinogen deaminase N-terminal" evidence="15">
        <location>
            <begin position="63"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobilinogen deaminase C-terminal" evidence="16">
        <location>
            <begin position="288"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00074324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH59926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="376" mass="40896" checksum="6B9C177AB00B65D5" modified="2009-05-26" version="1">MASVAITASFSASVDFTSVSTRKLSFRSKFLSVSPPLAASSAHRTSRNRNVVRVVAEVDEPIVKIGTRGSPLALAQAYMTRDLLKKNFVELSEEGALEICIIKTTGDKVLDQPLADIGGKGLFTRELDVALLDGRIDIAVHSMKDVPTYLPEGSILPCMLPREDVRDAFISVKYDDLSELPDGALVGTASLRRQSQLLAKFPTLKCVNFRGNVQSRIRKLQEGVVDCTLLAIAGLNRMDMTEHATKILETDVMLPAVAQGAIGIACRTGDSRQLEFLEKLNHEETRIAVECERAFLASLDGSCRTPIAGYAYKSGNNLEFRGLVASLDGKQILETTRSSNWSFTDAIDAGKDAGNELKALAPSEFFENLLEHGGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLK1</accession>
    <name>C1MLK1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">COP9 signalosome complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FUS12</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_70801</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056181.1">
        <property type="nucleotide sequence ID" value="XM_003056135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLK1"/>
    <dbReference type="STRING" id="564608.C1MLK1"/>
    <dbReference type="GeneID" id="9682043"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70801"/>
    <dbReference type="eggNOG" id="KOG1464">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SEENWKD"/>
    <dbReference type="OrthoDB" id="194139at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000006">
        <property type="entry name" value="COP9 signalosome complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="241"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="439" mass="50532" checksum="017547DB554BA114" modified="2009-05-26" version="1">MTDDELEDYGFEYSDEDPDEADVDAENQYYFAKALLEAGSFKDAFDGFSAVLVMEKEPGEWGFKALKQIVKLHLKHGDYEDMLITYRQLLKYVSSAVTRNYSEKVLNSIIDAVSVSPNAMFRQEFYETTLCTLEDDKNARLCFKTNLKLCNLWLSMKEFVRVGKLIKKLHQACLKNDGSFDQQKGTQILEVYAIEIQMYTEQKNNKRLKETYLRALTVTSAIPHPHILGIIRECGGKMHMAERQWGEAATDFFESFKSYDEAGQSRRIQSLKYLVIANMLMESDVNPFDAQETRSFRSDPEVVVITSLVSAYHRNSISDFEALLITNNQHIIEDPFIHDYVEELLKNLRTQVLLKLIKPYTRVRFSVISSELNIPEVDVEALLVCLVLDSRVEADIDQTTQTVALGAYMHACRGSRNRGWEKWAAFIKAHTRIQTLRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLK3</accession>
    <name>C1MLK3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-disulfide reductase (NADPH)</fullName>
            <ecNumber evidence="2">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">TR</name>
        <name evidence="16" type="ORF">MICPUCDRAFT_70201</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="2"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056182.1">
        <property type="nucleotide sequence ID" value="XM_003056136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLK3"/>
    <dbReference type="STRING" id="564608.C1MLK3"/>
    <dbReference type="GeneID" id="9681800"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70201"/>
    <dbReference type="eggNOG" id="KOG4716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MPTKYDL"/>
    <dbReference type="OrthoDB" id="5956163at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000190">
        <property type="entry name" value="Thioredoxin reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000004">
        <property type="entry name" value="Thioredoxin reductase 1, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006338">
        <property type="entry name" value="Thioredoxin/glutathione_Rdtase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01438">
        <property type="entry name" value="TGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF8">
        <property type="entry name" value="THIOREDOXIN-DISULFIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="3 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0712">Selenocysteine</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="15">
        <location>
            <begin position="10"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="14">
        <location>
            <begin position="362"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="472"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="193"/>
            <end position="200"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="56"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH59558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="497" mass="53668" checksum="C717A3635ADD364A" modified="2009-05-26" version="1">MSTNLQAFDYDLVVVGGGSGGLATAKEAAKLGAKVACLDFVKPSPAGTSWGLGGTCVNVGCIPKKLMHQAGILGESFSDAREFGWKLRSDGHDWSKMVNGIQDHIGSLNFGYRTALRDNNVTYINAFGSFIDEHTITATKKNGKVDKITSERFVIAVGGRPSYLDVPGARECCITSDDVFSLPKPPGKTLCVGASYISLETAGFLTALGYDTTVAIRSVPLRGFDSEIAEMVVSHMERHGTNFMRDSQPVAFEKAADGQIKVSIKNTVFGSEFAAVFDTVILAVGRMAVTEGLNLATAGVHVNPKNGKIPAVDEVTNVPHIFAIGYVLDTRQELTPVAIKAGVRLARRLYSGSTEKMDYSLVPTTVFTPQEYGCIGMSEEQAIEMYGEENVEVYHSYFKPLEWTINHEALDGVAHREDNSCYSKLITNLSDDERVIGFHYIGPHAGEVTQGYAVAMRMGAKKRDFDGTVGIHPTVSEEFTTLSITKRSGVDAAKKGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLL5</accession>
    <name>C1MLL5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_55757</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056586.1">
        <property type="nucleotide sequence ID" value="XM_003056540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLL5"/>
    <dbReference type="STRING" id="564608.C1MLL5"/>
    <dbReference type="GeneID" id="9681804"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55757"/>
    <dbReference type="eggNOG" id="KOG2945">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NHGAPAR"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039764">
        <property type="entry name" value="HABP4/SERBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006861">
        <property type="entry name" value="HABP4_PAIRBP1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019084">
        <property type="entry name" value="STM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299:SF17">
        <property type="entry name" value="AT19571P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299">
        <property type="entry name" value="HYALURONIC ACID-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09598">
        <property type="entry name" value="Stm1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01233">
        <property type="entry name" value="HABP4_PAI-RBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hyaluronan/mRNA-binding protein" evidence="4">
        <location>
            <begin position="95"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="18"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="221"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="77"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="307" mass="32527" checksum="7C6214966B1E43A2" modified="2009-05-26" version="1">MAFQGANMFALLDEEDGPKPVAATKAPAAKTAPAAKKPAKLPEKHAAPGRGVSAGRGIARTPRAPREFEGEVVGSEGRPRQSGRNDRRDKPRNNDARRNDRQDRSGRGREGLHRGGAGKGGWGKPGEEASLVPEFTAEGEQEEIVPDEPDNEVTLEDYEKAKAERKTALMASLKQKNKGGASKTVDESAFTGMKLTSKDDGVDVLSSFELEGSETIKGKRVRTKNGVQKTILDTGFKTTPSAPADDRGGRGGRGRGDRDSGHGVSRGRGFRDGGRGVVRGARPGNARGSGFSAKIDDDSAFPTLGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLN7</accession>
    <name>C1MLN7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PsbB mRNA maturation factor Mbb1, chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55780</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056197.1">
        <property type="nucleotide sequence ID" value="XM_003056151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLN7"/>
    <dbReference type="STRING" id="564608.C1MLN7"/>
    <dbReference type="GeneID" id="9681809"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55780"/>
    <dbReference type="eggNOG" id="KOG1124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DDASWIM"/>
    <dbReference type="OrthoDB" id="541719at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044624">
        <property type="entry name" value="Mbb1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44917">
        <property type="entry name" value="PROTEIN HIGH CHLOROPHYLL FLUORESCENT 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44917:SF1">
        <property type="entry name" value="PROTEIN HIGH CHLOROPHYLL FLUORESCENT 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13428">
        <property type="entry name" value="TPR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="238"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="586" mass="65136" checksum="0F5B8D457AF941D1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLS9</accession>
    <name>C1MLS9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Voltage-gated ion channel superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MICPUCDRAFT_32293</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056815.1">
        <property type="nucleotide sequence ID" value="XM_003056769.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MLS9"/>
    <dbReference type="GeneID" id="9682254"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32293"/>
    <dbReference type="eggNOG" id="KOG2301">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DPFYHNQ"/>
    <dbReference type="OrthoDB" id="496478at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008331">
        <property type="term" value="F:high voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.350:FF:000009">
        <property type="entry name" value="Voltage-dependent T-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031649">
        <property type="entry name" value="GPHH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002077">
        <property type="entry name" value="VDCCAlpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF7">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16905">
        <property type="entry name" value="GPHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00167">
        <property type="entry name" value="CACHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 15" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="3 15" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="8 15" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="151"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="513"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="542"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="638"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="682"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="719"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="783"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="899"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1017"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1054"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1104"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1203"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="18">
        <location>
            <begin position="37"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="18">
        <location>
            <begin position="343"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="18">
        <location>
            <begin position="636"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="18">
        <location>
            <begin position="987"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="domain" description="Voltage-dependent L-type calcium channel IQ-associated" evidence="19">
        <location>
            <begin position="1248"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="577"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="577"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="873"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF16905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEH58460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1405" mass="158600" checksum="29D30311C37ED255" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLV3</accession>
    <name>C1MLV3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_38745</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056830.1">
        <property type="nucleotide sequence ID" value="XM_003056784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLV3"/>
    <dbReference type="STRING" id="564608.C1MLV3"/>
    <dbReference type="GeneID" id="9682723"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38745"/>
    <dbReference type="eggNOG" id="KOG2171">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RECAHEC"/>
    <dbReference type="OrthoDB" id="7862313at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="864" mass="85842" checksum="9A9BDBCDDCB14D1F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM88</accession>
    <name>C1MM88_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_15667</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057357.1">
        <property type="nucleotide sequence ID" value="XM_003057311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM88"/>
    <dbReference type="GeneID" id="9682796"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15667"/>
    <dbReference type="eggNOG" id="ENOG502S7DT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MTQPIPP"/>
    <dbReference type="OrthoDB" id="530342at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36776">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36776:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="121" mass="13936" checksum="BF6C8B03C15EC431" modified="2009-05-26" version="1">MRQITRDERDAEIAWLAGMLKLWLDDEWSIQEPHRDLGMRAAEKCTEMRLEGCEEMGSLVMGVAQELIDFDFSDTFVNAFEVANKCSEILMMREGYEVCCINKDDETRQERYDALVAAGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMC0</accession>
    <name>C1MMC0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_49521</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057377.1">
        <property type="nucleotide sequence ID" value="XM_003057331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMC0"/>
    <dbReference type="STRING" id="564608.C1MMC0"/>
    <dbReference type="GeneID" id="9682343"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49521"/>
    <dbReference type="eggNOG" id="KOG0078">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ENIRTWF"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01867">
        <property type="entry name" value="Rab8_Rab10_Rab13_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000308">
        <property type="entry name" value="ras-related protein RABE1c-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="204" mass="22503" checksum="1F9BC141FFCBC1DA" modified="2009-05-26" version="1">MGAVNQQYDHLIKLLLIGDSGVGKSCLLLRFSDDSFTTSFITTIGIDFKIRTVELDGKRVKLQIWDTAGQERFRTITTAYYRGAMGILLTYDVTDETSFNNVRNWMRNIEQHASENVNKILVGNKCDMEDKRVISHARGKALADEFGIPFFETSAKANVKVEDAFFSIARDIKNRLKSDKENAGGGGIKLGSGKGGSGSKSSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMD4</accession>
    <name>C1MMD4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_5571</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057383.1">
        <property type="nucleotide sequence ID" value="XM_003057337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMD4"/>
    <dbReference type="GeneID" id="9682822"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5571"/>
    <dbReference type="eggNOG" id="KOG3019">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YLPWIHI"/>
    <dbReference type="OrthoDB" id="276721at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05242">
        <property type="entry name" value="SDR_a8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013549">
        <property type="entry name" value="DUF1731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010099">
        <property type="entry name" value="SDR39U1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01777">
        <property type="entry name" value="yfcH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11092:SF0">
        <property type="entry name" value="EPIMERASE FAMILY PROTEIN SDR39U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11092">
        <property type="entry name" value="SUGAR NUCLEOTIDE EPIMERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08338">
        <property type="entry name" value="DUF1731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1731" evidence="2">
        <location>
            <begin position="257"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="304" mass="32344" checksum="4C9599162EEB1CD3" modified="2009-05-26" version="1" fragment="single">LRVAISGASGFVGTKLVAKLLAAGHEVLVLARDVNKARSALKPETLPRGVVVFVPLSQWAAAVADVDAVVNLAGEPISTRWSPAIKAEIMASRVKATKRIVDAVEALEERRRPKVLVNASAIGFYGTSENATFDESAPPGGDYLSKVCQSWEQTAMAVENVGVRVVLLRLGIVLDRDGGALGKMLPTFQVFAGGPMGDGSQWFSWIHREDAVGIIMEAISNESMSGPVNVTAPNPVRMGEMCTEIGAALGRPSWLPVPDFAIQALLGEGATVVLRGQKVAPSAVLRSGYKFKYERIDDALKNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MME8</accession>
    <name>C1MME8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46785</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057392.1">
        <property type="nucleotide sequence ID" value="XM_003057346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MME8"/>
    <dbReference type="STRING" id="564608.C1MME8"/>
    <dbReference type="GeneID" id="9682356"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46785"/>
    <dbReference type="eggNOG" id="ENOG502S18V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MFWALTR"/>
    <dbReference type="OrthoDB" id="413408at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035770">
        <property type="term" value="C:ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901259">
        <property type="term" value="P:chloroplast rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000963">
        <property type="term" value="P:mitochondrial RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044528">
        <property type="term" value="P:regulation of mitochondrial mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050870">
        <property type="entry name" value="FAST_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228">
        <property type="entry name" value="FAST LEU-RICH DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228:SF40">
        <property type="entry name" value="LD45607P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="2">
        <location>
            <begin position="929"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="940"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="972"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1039" mass="110669" checksum="B1D8CBB5FE871D36" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMP0</accession>
    <name>C1MMP0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_56602</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I LYR family. SDHAF1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056962.1">
        <property type="nucleotide sequence ID" value="XM_003056916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMP0"/>
    <dbReference type="STRING" id="564608.C1MMP0"/>
    <dbReference type="GeneID" id="9682878"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56602"/>
    <dbReference type="eggNOG" id="KOG4620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VEMYSSP"/>
    <dbReference type="OrthoDB" id="273010at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20268">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045295">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="5">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="81" mass="9060" checksum="03DB5B6F563FDD9D" modified="2009-05-26" version="1">MAPARLSGLAKQVLSLHRSLLRAARSKDATARAAISRQIRDDFERHARLDPRKDVLLVEHLIRAGNKKLAMLRDPNVVGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMR8</accession>
    <name>C1MMR8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_56630</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056976.1">
        <property type="nucleotide sequence ID" value="XM_003056930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMR8"/>
    <dbReference type="GeneID" id="9682415"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56630"/>
    <dbReference type="eggNOG" id="ENOG502S4QX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EWRCKWD"/>
    <dbReference type="OrthoDB" id="497128at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="141" mass="15422" checksum="D39DA00EED2BD4CE" modified="2009-05-26" version="1">MRRALLQIARAHPTRASFLPPALLSQTRKMPTIVDGVDFAHVAREWRCKWDTADDKASLAACQKALATKLDAIKAVPGVVSVQRVVCGGCQDFKVIAKLEAAKFADWEAAAFAPEAEFLKEVEAIPGVKKVETQTFTLEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MND8</accession>
    <name>C1MND8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_5295</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056634.1">
        <property type="nucleotide sequence ID" value="XM_003056588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MND8"/>
    <dbReference type="STRING" id="564608.C1MND8"/>
    <dbReference type="GeneID" id="9682526"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5295"/>
    <dbReference type="eggNOG" id="ENOG502QUQW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IDHQCAF"/>
    <dbReference type="OrthoDB" id="9675250at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008663">
        <property type="term" value="F:2',3'-cyclic-nucleotide 2'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047734">
        <property type="term" value="F:CDP-glycerol diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16509">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16509:SF1">
        <property type="entry name" value="MANGANESE-DEPENDENT ADP-RIBOSE_CDP-ALCOHOL DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="320" mass="35951" checksum="0498290F325B014A" modified="2009-05-26" version="1" fragment="single">SSSPSPDFRFGLLADIQYTDTDDRTNFTGTQVRRYRNSLAVASDAIAFFNRYDDLSFVLHNGDIIDHQCAFDFETDAFKPKRVSYDHLGEVMRVLDDSACKEWVFTVGNHELYNFTRDELRRVLSSHWSPYDRTGSFYYAMRPARGWKVIVLDAYDVSVYGNGRGEGLDRAAVELLCEHNPNCARWVEDNPDVFETERMSGTFPYFQGLEGLGTRRVPFNGAVSEAQLRWLREELIAAKASEERVVVFSHLLVHPASTAKGSGRTLLWNYDAVLAVLEDDAYAANVSAVVSGHQHEGGLHTSEAGTHYVVMESPMLATPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNG4</accession>
    <name>C1MNG4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55886</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057101.1">
        <property type="nucleotide sequence ID" value="XM_003057055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNG4"/>
    <dbReference type="GeneID" id="9682540"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55886"/>
    <dbReference type="OMA" id="WEGAANG"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="214" mass="23446" checksum="ABA7D5CCA544F497" modified="2009-05-26" version="1">MTLARVSVPRPTQLDASEKSHAALESAVATTSRDSAAALLDARSSFSIHLESSLAASRDDAASDHAALVAELAETTKTLDAKARETSIAIMSYDDELRSVAAALEDVKARVGPERDYQIACSRWPVRASVDFIKDVDDDKRRLARRCATVVLNARENARERRMKRYGETFGEVSAFIATSRENQTRRMIETAARVEQVHRRIVGKGGWEGAANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPR4</accession>
    <name>C1MPR4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">lipoyl(octanoyl) transferase</fullName>
            <ecNumber evidence="3">2.3.1.181</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">LIPB</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_70185</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LipB family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="3"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057997.1">
        <property type="nucleotide sequence ID" value="XM_003057951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPR4"/>
    <dbReference type="STRING" id="564608.C1MPR4"/>
    <dbReference type="GeneID" id="9683090"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70185"/>
    <dbReference type="eggNOG" id="KOG0325">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ARRWVTY"/>
    <dbReference type="OrthoDB" id="19908at2759"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993:SF7">
        <property type="entry name" value="LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993">
        <property type="entry name" value="OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="6">
        <location>
            <begin position="124"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="377" mass="40463" checksum="F86B3E61C2BF89DA" modified="2009-05-26" version="1">MAKDAAAKKVPGGGGVESTVKKIAKKIAGKGRRDAAKKPVAAKAAAAIDASNNIVSDDPAPNDAVNVDTKTIDFYDMSDTLTPYVEAWEWQKTLVDARLRSLDPKNAEHEVAEAKRRGDPPPIFQDRDCLILVQHPPVVTLGTGSTSDNLKFDPEDVNAPFAVHRTERGGEATYHGPGQLVIYPVFNLREHQTDLHWYMRSLEEVAIKAMRELGVENPGRVEGLTGAWANVPPSGAQEKEAASTPLAEKPHKVAAIGVRARRWVTYHGMAFNVCPDLNDFTSIVPCGIGDRPVGSIAQLLAKREGIVSTEEGSYGGGGDGGGEVFEDAALMATSKSALLKAFESVFKVDLNKRGGPPPLRALKAGDKIKCDSCRYLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPZ0</accession>
    <name>C1MPZ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_39219</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058033.1">
        <property type="nucleotide sequence ID" value="XM_003057987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPZ0"/>
    <dbReference type="STRING" id="564608.C1MPZ0"/>
    <dbReference type="GeneID" id="9683471"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39219"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42462at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="575" mass="63144" checksum="AC991060470557CE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR58</accession>
    <name>C1MR58_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_10647</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057873.1">
        <property type="nucleotide sequence ID" value="XM_003057827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR58"/>
    <dbReference type="STRING" id="564608.C1MR58"/>
    <dbReference type="GeneID" id="9683685"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_10647"/>
    <dbReference type="eggNOG" id="KOG1549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GTSRKWL"/>
    <dbReference type="OrthoDB" id="7403325at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586:SF24">
        <property type="entry name" value="BLR4730 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="5">
        <location>
            <begin position="5"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="375" mass="40811" checksum="228F53EA534045BA" modified="2009-05-26" version="1" fragment="single">DVAHFNSAGSSPPPKPVLDAQLEYLAVEANLGGYETAELSKRELRRPYAELATMLGCERDEIAITQSATSAWQLAFSSLERTFARGDRVLVARAEYASNYIAYLQASERTGVVVEVIPSDAYGQVDADALDATLSDASKGKCRLVSIVHVPTSSGLVNDAVAIGAVAKKHGVPYLLDACQSVGQMPVNVNEIGCDFLCGTGRKYLRGPRGIGFLYARGETVEAMNLVPAYMDLHGATWEETETYEPAEGAKRFEQYEVSFAAKVGLGAAVAYANAIGVDAGWRRTRYLAETLRVGLRDVKRVVVHDQGEVQCGIVTFTVGGVSPFDVRRRLARDGVKVWTSNVKNNTKLEHEREEGTPEVVVRASVHYFNTEEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR82</accession>
    <name>C1MR82_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_39493</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057885.1">
        <property type="nucleotide sequence ID" value="XM_003057839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR82"/>
    <dbReference type="STRING" id="564608.C1MR82"/>
    <dbReference type="GeneID" id="9683697"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39493"/>
    <dbReference type="eggNOG" id="KOG2044">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="542656at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000003">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF41">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="7">
        <location>
            <begin position="14"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="287"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="398" mass="42934" checksum="A35BDF44A2125A4C" modified="2009-05-26" version="1">MDGNTCPVDCSAPNPNGQEFDNLYLDMNGIIHPCFHPEDRPAPTTEEEVFECIFDYIDRLFAMIRPRKLLYMAIDGVAPRAKMNQQRSRRFRAAQEAQEKEEEEEKLRETLRAEGVKVPDKVKSEAFDSNVITPGTPFMGRLSAALQYYVHQRLNTDPGWRGVKVIMSDASVPGEGEHKAMHYIRQQRGLNGFDPNTRHVVYGLDADLIMLALATHEPNFHILREVVFQKNAPPPDVPSTRDQIMGEGAPGSMYGGNRGGPGPGLSQGAHRLLQASVHAGVGGGGASGVMQYGHHPGPGPGGMPLGGHRGPYGGGPPLAQQGYPGPPPPGPPMMYGHQGQQYPGPPQMGGFPGPPPRGQQYPGYPGPPGPPRGGGNSFAALGNLPPRGGNNDPRYTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRI0</accession>
    <name>C1MRI0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_39551</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057930.1">
        <property type="nucleotide sequence ID" value="XM_003057884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRI0"/>
    <dbReference type="STRING" id="564608.C1MRI0"/>
    <dbReference type="GeneID" id="9683750"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39551"/>
    <dbReference type="eggNOG" id="KOG0667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QARIIHC"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF17">
        <property type="entry name" value="HOMEODOMAIN INTERACTING PROTEIN KINASE, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="107"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="490"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="578"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="586"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="605" mass="63972" checksum="0D6EF66124CCD1F1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRY2</accession>
    <name>C1MRY2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58274</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058587.1">
        <property type="nucleotide sequence ID" value="XM_003058541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRY2"/>
    <dbReference type="GeneID" id="9684394"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58274"/>
    <dbReference type="eggNOG" id="ENOG502S5TI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CWQPMGV"/>
    <dbReference type="OrthoDB" id="567951at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="371" mass="40598" checksum="CD2F17B7D7BB081B" modified="2009-05-26" version="1">MARSATRVEHPRPPARDDAASASSSALPSSRDIEAEFGLYAGDECDVEIDDEGDVRCACEGCARWKAYVSGTLGPPHPTWPQYEVFTREHMRALAEYLSKRARAYADEDEDEDRPRRRALEVLEVGAGDGRLSRALNDECAAIARASPSRGVSVTVRPTDDGSLGLARGDRVVRDGAPEPPERVDAAAALERYRPTIVLACWQPMGVDWTAAMRACDAVREYVLVGETDDGVCGRPWETWGYRGGGGGGGGGGGDGDDSDDDDDARRVSYEIEAAFSGDFETDVAAFRLAMRRDPHVAAVVNGSRTEKEDSDDADSDDEPPPHEKDGFARVDLKDVSARQICRTDERWRARRQSRTVSFRRVGKEDGRNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSW1</accession>
    <name>C1MSW1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_5818</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058390.1">
        <property type="nucleotide sequence ID" value="XM_003058344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSW1"/>
    <dbReference type="STRING" id="564608.C1MSW1"/>
    <dbReference type="GeneID" id="9684190"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5818"/>
    <dbReference type="eggNOG" id="KOG1260">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905:SF2">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13714">
        <property type="entry name" value="PEP_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="289" mass="30219" checksum="422C6A08840634E6" modified="2009-05-26" version="1" fragment="single">ASALRDVLSKDGCELMPGVYDALGARLLAANDFQCAFMSGYGVAASRLGDPDVGLADLTAMTDAGTAVCRAAGAMPVVGDGDAGFGGVANVRRTVLAYHAAGFAAVSIEDQIFPKRCAFSDGMRVVSRAEAVARVAAAVDARDEIRARGGDFMIVARTDARLASDGGGGAFEEAMWRCAAFEDLGADVVYFEGPDGEREMEAFNARVATPFTMLAQVEKPGRKLLTPTECANLGYDAVLHGLTLLSASVRGVNAAIEAMKEGNRAVGDELLTPFDALYEAVGFEEHYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT42</accession>
    <name>C1MT42_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_17460</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058426.1">
        <property type="nucleotide sequence ID" value="XM_003058380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT42"/>
    <dbReference type="STRING" id="564608.C1MT42"/>
    <dbReference type="GeneID" id="9684235"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17460"/>
    <dbReference type="eggNOG" id="KOG1423">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YVIDHRL"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043024">
        <property type="term" value="F:ribosomal small subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22534">
        <property type="entry name" value="KH-II_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTPase_Era-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="GTPASE ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698:SF1">
        <property type="entry name" value="GTPASE ERA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="5">
        <location>
            <begin position="4"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="4">
        <location>
            <begin position="12"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="4">
        <location>
            <begin position="38"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="4">
        <location>
            <begin position="59"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="4">
        <location>
            <begin position="144"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="4">
        <location>
            <begin position="176"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="322" mass="36252" checksum="6093F79E784DA31C" modified="2009-05-26" version="1" fragment="single">EAQKTITVGIVGVPNAGKSQLTNTLAGSQVSAVSPKTNTTRIETLATITKRETQVILVDLPGVVGREHYRNGVHEKKVSSAWSAAADCDALVFIVDAHRQLSRPDPRVVRLIARARESLDAMKTEAEKLEGDGALRVPSFLALNKLDLFEPWERDRVKALARQLSKLHDFARVFPISAKRGKGTDALLRGLIEIAPTKPWAFDPTQVTDKTSIDQAIEVVRECVYQRLHKELPYNIVPIHDEWENRRDGSVKIEQYLVVDNVGVKQIVVGRRGSTIGQIGIRARVLLEKMWDKRVHLILNVRVRKKNNTVRGRLRPEEFEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTD3</accession>
    <name>C1MTD3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_7713</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058468.1">
        <property type="nucleotide sequence ID" value="XM_003058422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTD3"/>
    <dbReference type="STRING" id="564608.C1MTD3"/>
    <dbReference type="GeneID" id="9683907"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7713"/>
    <dbReference type="eggNOG" id="KOG2397">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NARHEFT"/>
    <dbReference type="OrthoDB" id="28322at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017177">
        <property type="term" value="C:glucosidase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039794">
        <property type="entry name" value="Gtb1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036607">
        <property type="entry name" value="PRKCSH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12630:SF17">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12630">
        <property type="entry name" value="N-LINKED OLIGOSACCHARIDE PROCESSING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13015">
        <property type="entry name" value="PRKCSH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="MRH" evidence="3">
        <location>
            <begin position="44"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="145" mass="16045" checksum="24C99E4593077CAA" modified="2009-05-26" version="1" fragment="single">ANRLRDAWSADATALRETEDALRENEARLTRFMGEDDEYAYMVGECYEAKVDKYVYEACPFGKASQDSTSLGTMQDIDRASPRTFKFTGGEGCWNGPARSLTATARCGAENKLAEVIETSRCEYVATLVTPAACAEDEERAAREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTH2</accession>
    <name>C1MTH2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58068</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058863.1">
        <property type="nucleotide sequence ID" value="XM_003058817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTH2"/>
    <dbReference type="GeneID" id="9683928"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58068"/>
    <dbReference type="OMA" id="FGMEHYF"/>
    <dbReference type="OrthoDB" id="5561579at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="109" mass="11584" checksum="2D26BC0F35498F05" modified="2009-05-26" version="1">MFGWYRRAFIDTGSSAPLTHVMAGVWAMAFGMEHYFHHKYHSHSEAAHPATEGGDAAAPSAAAAAAKPADDEKPRTMEELKKEVEELRGDVAAMKKAVAPPAPAPAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTI3</accession>
    <name>C1MTI3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase</fullName>
            <ecNumber evidence="4 15">2.7.4.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MICPUCDRAFT_17536</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:37459"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:37460"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:10276"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:10277"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 15">Cytoplasm</location>
            <location evidence="2 15">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the histidine acid phosphatase family. VIP1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="4 15"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058868.1">
        <property type="nucleotide sequence ID" value="XM_003058822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTI3"/>
    <dbReference type="STRING" id="564608.C1MTI3"/>
    <dbReference type="GeneID" id="9683934"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17536"/>
    <dbReference type="eggNOG" id="KOG1057">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IQERWCC"/>
    <dbReference type="OrthoDB" id="18042at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033857">
        <property type="term" value="F:5-diphosphoinositol pentakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052723">
        <property type="term" value="F:inositol hexakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052843">
        <property type="term" value="F:inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000036">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11950:FF:000002">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037446">
        <property type="entry name" value="His_Pase_VIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040557">
        <property type="entry name" value="VIP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750">
        <property type="entry name" value="DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750:SF9">
        <property type="entry name" value="INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18086">
        <property type="entry name" value="PPIP5K2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VIP1 N-terminal" evidence="18">
        <location>
            <begin position="9"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp fold RimK-type" evidence="17">
        <location>
            <begin position="224"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="357"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="506"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="843"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1018"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1104"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="868"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1112"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1152"/>
            <end position="1162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00071668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF18086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH57323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1171" mass="130785" checksum="996283FCCE77F791" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU48</accession>
    <name>C1MU48_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58666</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059132.1">
        <property type="nucleotide sequence ID" value="XM_003059086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU48"/>
    <dbReference type="GeneID" id="9684875"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58666"/>
    <dbReference type="eggNOG" id="ENOG502SZH7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="561" mass="57536" checksum="528D2C7BBBDDB4C6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU91</accession>
    <name>C1MU91_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protochlorophyllide reductase</fullName>
            <ecNumber evidence="3">1.3.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PORB/C</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_17564</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.33" evidence="3"/>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059455.1">
        <property type="nucleotide sequence ID" value="XM_003059409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU91"/>
    <dbReference type="STRING" id="564608.C1MU91"/>
    <dbReference type="GeneID" id="9684595"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17564"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HDPAQKS"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="UniPathway" id="UPA00668"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016630">
        <property type="term" value="F:protochlorophyllide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005979">
        <property type="entry name" value="Prochl_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44419:SF19">
        <property type="entry name" value="PROTOCHLOROPHYLLIDE REDUCTASE A, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44419">
        <property type="entry name" value="PROTOCHLOROPHYLLIDE REDUCTASE C, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="435" mass="44633" checksum="F6D7DAEF5D9E007C" modified="2009-05-26" version="1">MTSQHLHARVARANAARGLRARVVAPAGRSIATARRSAIAVSAARAETDDAASAPASASSRRDVVLGGALALASSALAATTPVAIADEAPTTTETTTTTTRDRKSVVVTGSNSGIGLDGAAKLAARGYDVTLACRTLAKAQAAKASIEATAAANGVVLTGSLTPAECDLASLDSIRAFAASRRAAPLDALVLNAGVEFSGDNTVRRTADGFEITVGVNHLGHFLLTNLLLPDLEAAASASPQSDGTTPRVVVTASEVHDPASPGGNVGLGAGLGDLRGLAENGAAFEMLDGSPYDADKAYKDSKLCNVLFARELQRRLRDAGSVVTVNTFGPGLITRTGLFRAQNPLFVKVFDFATNEIFHVAETVDGGGDCLVRMVTDAELEGVGDVYYNNGIAPGEGKTGHKFERGDVSAEAMDGEKGKALWAYSERLVGLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUN6</accession>
    <name>C1MUN6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58876</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059528.1">
        <property type="nucleotide sequence ID" value="XM_003059482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUN6"/>
    <dbReference type="GeneID" id="9684968"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58876"/>
    <dbReference type="OrthoDB" id="495322at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="300" mass="31699" checksum="0ED76C7A6FA269F1" modified="2009-05-26" version="1">MTSPLALVASSAARAGPSKAGKRNRGSRRVAARGTAAPSKPKKKIVESSKRTPKRDAPERAAADMAHAITDEDSYPAFLVEYLEMACRPSPEPTSRREALSRAAAACSLGAVSSMMSFPTQPAAAIYNKDLDIPITDPTQAMATVFAARAAVQDVLAQIADFEETCPAPVFPCDLSQLSVKASTRVSGPLKRALPTLSEAYGADPYAVQDIIQSVSTCEAMLYANNARVKVDFKGPTTFFNLVDDSIEALLRECPEEAVAAGRARYDACDLSVAPEAEGEIECRLARAISSGARPKGGMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUT2</accession>
    <name>C1MUT2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ethanolamine-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="10">2.7.7.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">CTP:phosphoethanolamine cytidylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_17727</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.14" evidence="10"/>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059553.1">
        <property type="nucleotide sequence ID" value="XM_003059507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUT2"/>
    <dbReference type="STRING" id="564608.C1MUT2"/>
    <dbReference type="GeneID" id="9684688"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17727"/>
    <dbReference type="eggNOG" id="KOG2803">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FESNNWV"/>
    <dbReference type="OrthoDB" id="40021at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00742"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004306">
        <property type="term" value="F:ethanolamine-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02174">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041723">
        <property type="entry name" value="CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044608">
        <property type="entry name" value="Ect1/PCYT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780:SF2">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Cytidyltransferase-like" evidence="13">
        <location>
            <begin position="84"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Cytidyltransferase-like" evidence="13">
        <location>
            <begin position="283"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH56685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="457" mass="49731" checksum="D5CD4A7BC8A60082" modified="2009-05-26" version="1">MTTPRQRLDDAVKIINTFLKEKDIPPSTAIAAAVAGVTTLVGASVYLYPETFLGIRRGSFSMGIAGMLQRHAARRRARKPIRVYMDGCFDLTHFGHANALRQAKACGDVLVVGLVPDAEIRRCKGPPVLNDAERLAVVESCKWVDEMILDVPYDINEQFMNELWHKHKIDYIVHGDDPCLLPDGSDAYAAPKREGRFKTIKRTEGVSTTDIVGRMLSASKAAENDLAKTPGSKSPFKKSKKSAVVEDVAEPAKKEHFCTTSRRVLQFSDGGKKPSDEDVVVYVHGAFDTFHAGHVDLLKSARALGTFVIVGVHDDAAVSSYAGAHYPILNVNERSLGVMACRHADEVIIGAPEVVTRDLLATFNVAFVVAEDSAARSPNAPAPAPPADPNAVPRALGIFREIKRGDGPGADITTKEIVSRIVENRAAFEERNKRKGASEAKYYELKNAGEIESATEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUX4</accession>
    <name>C1MUX4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58967</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059266.1">
        <property type="nucleotide sequence ID" value="XM_003059220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUX4"/>
    <dbReference type="GeneID" id="9684706"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58967"/>
    <dbReference type="eggNOG" id="ENOG502QSFR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10249775at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042507">
        <property type="entry name" value="TBC1D19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16110">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16110:SF1">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="326"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="618" mass="67011" checksum="82E9268E2F8D95D2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV41</accession>
    <name>C1MV41_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_7385</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059306.1">
        <property type="nucleotide sequence ID" value="XM_003059260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV41"/>
    <dbReference type="STRING" id="564608.C1MV41"/>
    <dbReference type="GeneID" id="9685044"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7385"/>
    <dbReference type="eggNOG" id="KOG2056">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LMSNIAD"/>
    <dbReference type="OrthoDB" id="4033880at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03571">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276:SF45">
        <property type="entry name" value="CLATHRIN INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276">
        <property type="entry name" value="EPSIN/ENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="3">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="116" mass="13686" checksum="8515BD064D98CBF6" modified="2009-05-26" version="1" fragment="single">NDVEIAVMDATDNEKWGPHGADLKKIANLTRDRENLHYVMKTLRRRLEHRDEEWRHVYKALTVMEYLVAHGAEDCVRELRRDARDLERLSGFKYKEPNGRDQGINVRQKSQTIVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVH1</accession>
    <name>C1MVH1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59376</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060037.1">
        <property type="nucleotide sequence ID" value="XM_003059991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVH1"/>
    <dbReference type="STRING" id="564608.C1MVH1"/>
    <dbReference type="GeneID" id="9685190"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59376"/>
    <dbReference type="eggNOG" id="ENOG502QS0D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NSKNCDE"/>
    <dbReference type="OrthoDB" id="10259720at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036159">
        <property type="term" value="P:inner dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033290">
        <property type="entry name" value="CCDC39"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18962">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18962:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24161">
        <property type="entry name" value="CCDC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="210"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="308"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="427"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="502"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="677"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="890" mass="100675" checksum="4EAC2BF13679BF4F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVH3</accession>
    <name>C1MVH3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65392</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059752.1">
        <property type="nucleotide sequence ID" value="XM_003059706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVH3"/>
    <dbReference type="GeneID" id="9685191"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65392"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33487">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33487:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="841" mass="88871" checksum="BFB1CDBDE41EFEE4" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVQ7</accession>
    <name>C1MVQ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_27600</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059791.1">
        <property type="nucleotide sequence ID" value="XM_003059745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVQ7"/>
    <dbReference type="STRING" id="564608.C1MVQ7"/>
    <dbReference type="GeneID" id="9685521"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27600"/>
    <dbReference type="eggNOG" id="KOG3961">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IPIKXNS"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019399">
        <property type="entry name" value="Parkin_co-regulated_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21207:SF2">
        <property type="entry name" value="PARKIN COREGULATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21207">
        <property type="entry name" value="PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10274">
        <property type="entry name" value="ParcG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="200" mass="22792" checksum="C0F1DC6D04D58735" modified="2009-05-26" version="1" fragment="single">MSHRWPTTKPGTSEYLKRGDGEKIKSGRRRLARSKNVISWKVDVEKLDFHHYLPIFMDGVREKEEPYRFLAVKGVEDLLKAGGQKILPVIPQLIIPIKTALNTRDPSVVCIVVQLLQKLVVSAELVGEALVPYYRQILPILNLFKNRNNNVGDAIDYGQRKKACMGELILDTLQLFETYGGEDAFINIKYMVPTYESCIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW14</accession>
    <name>C1MW14_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65533</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059846.1">
        <property type="nucleotide sequence ID" value="XM_003059800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW14"/>
    <dbReference type="GeneID" id="9685573"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65533"/>
    <dbReference type="eggNOG" id="ENOG502SFSY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GQMEDVA"/>
    <dbReference type="OrthoDB" id="4535at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="715" mass="74470" checksum="9AC697B15BE81F68" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWG4</accession>
    <name>C1MWG4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59757</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060211.1">
        <property type="nucleotide sequence ID" value="XM_003060165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWG4"/>
    <dbReference type="GeneID" id="9685359"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59757"/>
    <dbReference type="eggNOG" id="ENOG502S137">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TQVIMFT"/>
    <dbReference type="OrthoDB" id="105136at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="663" mass="73136" checksum="4ECCEC7B339D8FBE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX85</accession>
    <name>C1MX85_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_19393</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060351.1">
        <property type="nucleotide sequence ID" value="XM_003060305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX85"/>
    <dbReference type="STRING" id="564608.C1MX85"/>
    <dbReference type="GeneID" id="9686087"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19393"/>
    <dbReference type="eggNOG" id="ENOG502QVXR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RENTHDR"/>
    <dbReference type="OrthoDB" id="206108at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.601.10">
        <property type="entry name" value="RNA Polymerase Primary Sigma Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050239">
        <property type="entry name" value="Sigma-70_RNA_pol_init_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30603">
        <property type="entry name" value="RNA POLYMERASE SIGMA FACTOR RPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30603:SF47">
        <property type="entry name" value="RNA POLYMERASE SIGMA FACTOR SIGD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="Sigma2 domain of RNA polymerase sigma factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="Sigma3 and sigma4 domains of RNA polymerase sigma factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA polymerase sigma-70 region 2" evidence="8">
        <location>
            <begin position="70"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase sigma-70 region 3" evidence="7">
        <location>
            <begin position="158"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase sigma-70 region 4" evidence="9">
        <location>
            <begin position="263"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="362"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH55120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="425" mass="45748" checksum="95B30BC53A893360" modified="2009-05-26" version="1" fragment="single">GRGKLLTADEEKELGGAIQQLLRIEAMENELVEASIAEELRRDKAAAAAADRGEIVTAIDAGQNARRQLVVKNVGLAYSIARDVFEKLNHADRGLLSVSDLAQEGCAGLAQAADKFDPSRGYKFSTYAYNWTRKYVVNAIQNNGRTIRLPIHMHEIMQRAKKATRELTQKHGRAPTDEEMSRTLGVPVSRVQEINDWARSTLSLDVGGGGRSSDDGDGGAEGMMDGIVFALGSKDGKDGMLSPHEAAEADMEADLLRRDLEEAFATLLPREAFVLRHRFGLAAAASTALGTLLGVSHETIRTYERRALEKLKQPSRAARFVRYLDKEDVERYTEAQGAKGAEELANALSAALVAADAKAGGGRIARRRNPATTPSPMIDLASDGGGGGGGGKAAATTKPRRARRPRKVDKSAESEATVEMTVEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXG1</accession>
    <name>C1MXG1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60146</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060686.1">
        <property type="nucleotide sequence ID" value="XM_003060640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXG1"/>
    <dbReference type="GeneID" id="9685829"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60146"/>
    <dbReference type="OMA" id="REDAKWG"/>
    <dbReference type="OrthoDB" id="10561944at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="315" mass="35025" checksum="141D6B8C2E7FD48E" modified="2009-05-26" version="1">MSSSTVASRAIPRARTRSVAWRALVPGSREFAAPSARASRRTSRGRDRAAAAGAAVAFVKPKGEWPRVNVAGERSWKGIQFDELSFEVKKCEDGAAATALVDEFVRSDGLTPEFLETCVDLTVLAHKQRRPAEEIAMLQELAVYLMREHRRRACPPEVFFADELLRTFDSETVAAAMRGDEAASIRVRNVRDALVRAFEHGVADVDDPDDDAPAVRLSQSVFMTHLERTRFRCVEDARRERSVAMDVVGADELGAFYTLVPIRPQVMRAYEPAGIDTMEEIRMSRDALLEAASRVETLAKMFKEHVWKGGGASER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXL3</accession>
    <name>C1MXL3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60202</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060418.1">
        <property type="nucleotide sequence ID" value="XM_003060372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXL3"/>
    <dbReference type="GeneID" id="9686148"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60202"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="341" mass="36171" checksum="5658FC9D48F916B4" modified="2009-05-26" version="1">MKTHAPIKQTQKARGRGSTLARANAVAARARFLRNREIPPSASVRAFRLAAPFRSPASFIRLTSRLALSPSRRRRRRPQPPARASAGARAALTPVAISPLFTVDGSELARARGPIDRPAATRRPPTTKHGGRRRVAAAATPPPDASTSSVCADKETRARRHDLMRDVAKRRVRGGDGGDDDANANACSVATVTVLRVDARVPFGAGKKRGDGPPRPIAEDRARATVDVPSSILPLYRAEPQRRPNAVTPAFNPGKIQPPSTRRDAFATRPTRAAAAAAARGRTSTASSSVLPPVDDLHIGGERAAAVEATERGAAATTTRAKNAIRYVLSHTGSHTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXL7</accession>
    <name>C1MXL7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucose-6-phosphate dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="3">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_18868</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060713.1">
        <property type="nucleotide sequence ID" value="XM_003060667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXL7"/>
    <dbReference type="STRING" id="564608.C1MXL7"/>
    <dbReference type="GeneID" id="9686150"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18868"/>
    <dbReference type="eggNOG" id="KOG0563">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HEEMYMK"/>
    <dbReference type="OrthoDB" id="60984at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF0">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="9">
        <location>
            <begin position="17"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="222"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="426"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="387"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="391"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH55482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="587" mass="64046" checksum="C44A2F21163F7BBA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXM0</accession>
    <name>C1MXM0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_60210</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060715.1">
        <property type="nucleotide sequence ID" value="XM_003060669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXM0"/>
    <dbReference type="STRING" id="564608.C1MXM0"/>
    <dbReference type="GeneID" id="9685859"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60210"/>
    <dbReference type="OMA" id="VYRWEIP"/>
    <dbReference type="OrthoDB" id="10249065at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="408"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="460"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="352"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="362"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="499"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="651" mass="68118" checksum="B04F05A4338E95C4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXR2</accession>
    <name>C1MXR2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47939</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060442.1">
        <property type="nucleotide sequence ID" value="XM_003060396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXR2"/>
    <dbReference type="STRING" id="564608.C1MXR2"/>
    <dbReference type="GeneID" id="9686173"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47939"/>
    <dbReference type="eggNOG" id="ENOG502QRFW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SEIRMHP"/>
    <dbReference type="OrthoDB" id="525079at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="497" mass="53117" checksum="CDB3896551EBD0C8" modified="2009-05-26" version="1">MGSGAAEASSSLGTPPRTPVHPDDAILLVGGYTHADLLAHTPRDVDASHARGVHVLRVCGVTGGMTRLSTNAIGPNVAFITRSPTNPQILYATTERIDDEGEVITLRITPEFTLREVSRVKTGGRSTCYVNFCKNKEYMMVVSYWDAKVSMLRVGPDGRPASPRSVIMQPEAKYVDDKRPTREEHWKFRQRWPHSHCCVTEPYTNLVHFVVDLGLDRVFAYRVCRVSGSLVLKGSVGLPRGKGPRHLLFHPTLRTAYLVNELDSTVSCFRVNLPASWVSSEATVAAAADAAISAPPPMEQECDTPGAALELIQCISSLPVSEQGKTTITPQGVWKAASHSSEIRMHPSGAYFVVGNRGHDSIATYAVDQRTGSIALVGITPSGGECPRNFNWTGGGAFLVVGCQNSNRMCAFRFDAATGSLTLAAALEGVASPNYVCSVPMSAVPELVTAAAPADATPTCVNDAIARVKSFEIGGIHHSHHGSASSDFDVAPASLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY11</accession>
    <name>C1MY11_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60359</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic/archaeal RNase P protein component 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060483.1">
        <property type="nucleotide sequence ID" value="XM_003060437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY11"/>
    <dbReference type="STRING" id="564608.C1MY11"/>
    <dbReference type="GeneID" id="9686231"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60359"/>
    <dbReference type="OMA" id="TETHEGR"/>
    <dbReference type="OrthoDB" id="10618287at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030681">
        <property type="term" value="C:multimeric ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3250">
        <property type="entry name" value="Ribonuclease P, Pop5 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002759">
        <property type="entry name" value="Pop5/Rpp14/Rnp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038085">
        <property type="entry name" value="Rnp2-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15441">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15441:SF1">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01900">
        <property type="entry name" value="RNase_P_Rpp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160350">
        <property type="entry name" value="Rnp2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="153" mass="16040" checksum="1D10BBC3B489E184" modified="2009-05-26" version="1">MAPPADGANASFDGPSYHIPQRTLDLRCDSAYFRVRMELSGESAAETSSRQTFQTAVTHALVRAHGVVGGAIPIEHLGFFAPAAAATATATTTSGGEGIIKCHVDDVDVLRSSLSLLTETHEGRGCRLIVVDVAETLTRIAKPTTSRTAFDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY28</accession>
    <name>C1MY28_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_41093</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060493.1">
        <property type="nucleotide sequence ID" value="XM_003060447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY28"/>
    <dbReference type="STRING" id="564608.C1MY28"/>
    <dbReference type="GeneID" id="9685931"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41093"/>
    <dbReference type="eggNOG" id="KOG3487">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RYMNQFI"/>
    <dbReference type="OrthoDB" id="10252102at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14825">
        <property type="entry name" value="TRAPPC2_sedlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="136" mass="15297" checksum="7643408BEE4F77C1" modified="2009-05-26" version="1">MVGLATFTIVSNADVPLYEANLGQTPKREDAAHLQEFVAHAALDVVDERRWETPQTNLKLVDRFNDLLVYAHVTAGGTRFVLLHDARNEESVRAFFAEAHELYVKAALNPFHDADSPIECAAFDDRVRALGRKYFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYM2</accession>
    <name>C1MYM2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_1495</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060299.1">
        <property type="nucleotide sequence ID" value="XM_003060253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYM2"/>
    <dbReference type="STRING" id="564608.C1MYM2"/>
    <dbReference type="GeneID" id="9686030"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_1495"/>
    <dbReference type="eggNOG" id="KOG4203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DGQYSIM"/>
    <dbReference type="OrthoDB" id="10257085at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02028">
        <property type="entry name" value="UMPK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="1">
        <location>
            <begin position="227"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="407" mass="45956" checksum="6A243DD62A17598C" modified="2009-05-26" version="1" fragment="single">QMTSIDEQLSFDKGFFLTIRAIQLLKQNAHDRPILVGIAGPSGAGKTVFCQKIQDFMPGIAVLSMDMYNDASMLLDGNFDDPRLTDYDLLNKNLSDLKAGKTIEAPIYDFKTSTRVGSRTVECPASKVIIVEGIYALSDRLRPLQDLRVSISGGVHFDLVKRVMRDIDRSGQQPEDIIHQAQSLVWNDHQISETVYPMYKAFIEPDLRSAHLKVYNSFNPFAGFQDPTYILKSDEVVDEAMAREVLSSDGFKHEEETEVTDIYLLPPGDDPETCTSWLRMRNRDGHYTLMFEETVCDGDVMISPRINFEVGVRILGGLMALGYEVGAIMKRLSKSWSDELLTIKVDWIEGLDRSYTQIQGKVRAAVEEAGTKLGLDGTYVPHSFIEQVQLERMTDELREMTAEMKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYT2</accession>
    <name>C1MYT2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipocalin/cytosolic fatty-acid binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41142</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060838.1">
        <property type="nucleotide sequence ID" value="XM_003060792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYT2"/>
    <dbReference type="STRING" id="564608.C1MYT2"/>
    <dbReference type="GeneID" id="9686533"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41142"/>
    <dbReference type="eggNOG" id="ENOG502S9PN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TISIWNT"/>
    <dbReference type="OrthoDB" id="565904at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912257" description="Lipocalin/cytosolic fatty-acid binding domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="25969" checksum="126CB29597A2EBF4" modified="2009-05-26" version="1">MPPPPPPSTLARALAASLALVLLNAPSNAQAGGRRGAAAEPCAPVSTASPFDLDAYAAHAWYVQQQQVVRYQPRESLYCVRASYRVNDDDAVDVYNTANVGGVDGPPQNSDGFRLRAVIDPDADDDAPSKLRVGPRFLPRFLYGPYWVVAVSPSEPRDESDPVGPGYDWAIVSGGQPTIPTGDDGKCRTGSGQNDSGFWLFTREKIASEATLEEMRAVASEKGFDLSALEPVTHEGCEYPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYX4</accession>
    <name>C1MYX4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_45744</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <location evidence="2">Coated pit</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061115.1">
        <property type="nucleotide sequence ID" value="XM_003061069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYX4"/>
    <dbReference type="STRING" id="564608.C1MYX4"/>
    <dbReference type="GeneID" id="9686298"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45744"/>
    <dbReference type="eggNOG" id="KOG0935">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IVCIENE"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030122">
        <property type="term" value="C:AP-2 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14833">
        <property type="entry name" value="AP2_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000004">
        <property type="entry name" value="AP complex subunit sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027156">
        <property type="entry name" value="APS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0168">Coated pit</keyword>
    <keyword evidence="6" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="11">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH54765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="154" mass="18557" checksum="EB78933DB1DC44BC" modified="2009-05-26" version="1">MIRFLLMQNRQGKTRLAKYYVPLDDDEKHQLEYEVHRLVVNRDPKFTNFVEFRNYKIIYRRYAGLFFSLCVDVNDNELALLEAIHLFVEVLDHYFGSVCELDLVFNFHKAYTVIDEFILAGEIQARSIHWSPYDRETSKKQIMERLEELEKVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ43</accession>
    <name>C1MZ43_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60596</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060892.1">
        <property type="nucleotide sequence ID" value="XM_003060846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ43"/>
    <dbReference type="GeneID" id="9686590"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60596"/>
    <dbReference type="eggNOG" id="ENOG502SFH0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FMNDIHE"/>
    <dbReference type="OrthoDB" id="497711at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056683">
        <property type="entry name" value="DUF7781"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25003">
        <property type="entry name" value="DUF7781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7781" evidence="2">
        <location>
            <begin position="74"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="266" mass="30070" checksum="FA8414579702B5E1" modified="2009-05-26" version="1">MSEDGELLDYDSASTTPRSSEYDDADVQIRAESESETPPTRRRSPARRPNSALAAALGRAERAREGVEDFMNDIHEAYSFDLDPEYRVKVVKRFDGIALGARYDLKSRVFKVKVKEAPRRDESDGRFKFWKVFKKAEYAPEGGVAEVFTRPLRWGILSLQAIGGYKQETGNFSFRWKATSTVWETARGEVMRRTERDVNDRLSAALRWDLDVRPPKAEGGVSTGEGGESRAMDIDIGSYHVAVPRVELKLDLSGETEAARRRREGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ64</accession>
    <name>C1MZ64_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63299</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060904.1">
        <property type="nucleotide sequence ID" value="XM_003060858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ64"/>
    <dbReference type="STRING" id="564608.C1MZ64"/>
    <dbReference type="GeneID" id="9686599"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63299"/>
    <dbReference type="eggNOG" id="ENOG502QVNS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MTWPRVP"/>
    <dbReference type="OrthoDB" id="549381at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14873">
        <property type="entry name" value="OS06G0694100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14873:SF1">
        <property type="entry name" value="OS06G0694100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="505" mass="52937" checksum="96A57166189E0F66" modified="2009-05-26" version="1">MNLLRAILGVLPDKERHPPRKPRDERREGADIPARSSVDVPPPPPSGKRPPLIIELIDDDEPAGRGTAGVENEDGGEPQSTSLNDDTDMEIMSVATAAALAAAAYAKAATVHGAGGLPGWSSPEAAEAARVLLQRTFASRASGATTSSGSEYSDFTREILAKCLSEAAPSIAHCLAQEPEQRWAGESSARDKRAPGPPTPELPVDISATLQPASVETSVIAAVRLHWLLSTAGYPWVGRVGSGKDGGVGGVVSRVVPCILRAMDHNSPAVRREGCAALVALVAAVTRTEMRWHGAALLDAAANTLGGSGTEVFGAAAAAHVRATIAVSSDDPHEPKLANALAVMIDAANSRSHEPLVAAAWVIEAPALISAAKLSTAPHLNRLFPPLLSWLHARDDDTALGAASCLELICTMTWPRVPAHAAELWSDIARAYSEADVRGDDAFVFKFRAALTRVADVVQLAAGENFEAAWRRDGDPVPPALEPLVAHLEGLPGRVASTEWSRPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ82</accession>
    <name>C1MZ82_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60637</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060912.1">
        <property type="nucleotide sequence ID" value="XM_003060866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ82"/>
    <dbReference type="GeneID" id="9686609"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60637"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20401">
        <property type="entry name" value="Tudor_AtPTM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047365">
        <property type="entry name" value="Tudor_AtPTM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21743">
        <property type="entry name" value="PTM_DIR17_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTM/DIR17-like Tudor" evidence="2">
        <location>
            <begin position="424"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="558" mass="62360" checksum="DDE512560F276080" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZE0</accession>
    <name>C1MZE0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL30m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_60697</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061199.1">
        <property type="nucleotide sequence ID" value="XM_003061153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZE0"/>
    <dbReference type="STRING" id="564608.C1MZE0"/>
    <dbReference type="GeneID" id="9686638"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60697"/>
    <dbReference type="eggNOG" id="ENOG502S266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QKEANHR"/>
    <dbReference type="OrthoDB" id="509901at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_uL30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="5">
        <location>
            <begin position="3"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="84" mass="9525" checksum="5AE16089F27DF43B" modified="2009-05-26" version="1">MLYVTLRRGLAGKSKEYLKTLETLGLKRRFQVVEIPNNPASRGQISKVKHLVSVETAPQRAARIAAQEAKHAYREPIVFKHSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZM9</accession>
    <name>C1MZM9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_60788</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060980.1">
        <property type="nucleotide sequence ID" value="XM_003060934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZM9"/>
    <dbReference type="STRING" id="564608.C1MZM9"/>
    <dbReference type="MEROPS" id="C78.A02"/>
    <dbReference type="GeneID" id="9686688"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60788"/>
    <dbReference type="eggNOG" id="KOG2433">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="417506at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071567">
        <property type="term" value="F:deUFMylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012462">
        <property type="entry name" value="UFSP1/2_DUB_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48153">
        <property type="entry name" value="UFM1-SPECIFIC PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48153:SF2">
        <property type="entry name" value="UFM1-SPECIFIC PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07910">
        <property type="entry name" value="Peptidase_C78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UFSP1/2/DUB catalytic" evidence="3">
        <location>
            <begin position="498"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="689" mass="71394" checksum="EF9A50EF4AC5C5DA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZW1</accession>
    <name>C1MZW1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phosphoribosylformylglycinamidine cyclo-ligase</fullName>
            <ecNumber evidence="2">6.3.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_44665</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.1" evidence="2"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061023.1">
        <property type="nucleotide sequence ID" value="XM_003060977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZW1"/>
    <dbReference type="STRING" id="564608.C1MZW1"/>
    <dbReference type="GeneID" id="9686727"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44665"/>
    <dbReference type="eggNOG" id="KOG0237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CMHADGA"/>
    <dbReference type="OrthoDB" id="2018833at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004641">
        <property type="term" value="F:phosphoribosylformylglycinamidine cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046084">
        <property type="term" value="P:adenine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004733">
        <property type="entry name" value="PurM_cligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520:SF12">
        <property type="entry name" value="TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520">
        <property type="entry name" value="TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PurM-like N-terminal" evidence="6">
        <location>
            <begin position="39"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="7">
        <location>
            <begin position="174"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="388" mass="41863" checksum="2B2535D328207EF5" modified="2009-05-26" version="1">MARGVSADKEDVHAAIANVDKGLFPKAFCKVVPDLLTGDEEYCACMHADGAGTKSSLAYMYWKETGDLSVWRGIAQDAVIMNTDDLLCIGCVDNILLSSTIGRNKSLIPGEVLKALIGGTEDVLTTMRENGVGILSTGGETADVGDLVRTVIVDSTVTARMKRADVISNDAIAPGDVIVGMESYGQATYESEYNGGMGSNGLTSARHDVFGKYLASKYPESYDAAVPEDLVYSGKYVLTDVEPETGMTVGKLVLSPTRTYAPVIKKLLDVVDRKKIHGMVHCSGGAQSKVGHFLNDGLHVIKDDMLPVPPLFRLIQDCSGTEWEEMYKVFNCGHRMEVYCDAATAEEVIRVSESFNVKAQVVGRVEACEGKSKVTVKSEHGEFTYDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1N143</accession>
    <name>C1N143_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_20636</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061745.1">
        <property type="nucleotide sequence ID" value="XM_003061699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N143"/>
    <dbReference type="STRING" id="564608.C1N143"/>
    <dbReference type="GeneID" id="9687184"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20636"/>
    <dbReference type="eggNOG" id="KOG4280">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DIDCANA"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000083">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF36">
        <property type="entry name" value="KINESIN HEAVY CHAIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 6 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="46"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="431"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="580"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="147"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH54375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="621" mass="69608" checksum="D30B23FBB7D8A9C3" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>C1N248</accession>
    <name>C1N248_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 12">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_37587</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 12"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062229.1">
        <property type="nucleotide sequence ID" value="XM_003062183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N248"/>
    <dbReference type="STRING" id="564608.C1N248"/>
    <dbReference type="GeneID" id="9687468"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37587"/>
    <dbReference type="eggNOG" id="KOG1494">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MNPLVTE"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF47">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="8"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="152"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="13"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="122"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH53941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="319" mass="32927" checksum="5175DEF904C1791B" modified="2009-05-26" version="1">MTQTRGYKVAVLGAAGGIGQPCGLLMKMNPLVTELSLYDIAGTPGVAADVSHINTAAQVKGYAGDAELGAALKDADLVIIPAGVPRKPGMTREDLFKINAGIVAGLTEACATHCPNAMINMISNPVNSTVPIAAEVLKKRGAYDPKKLFGVTTLDVVRAKTFYAEKNGLETAKVDVPVVGGHAGITILPLLSQATPKAEMDAATIEALTKRTQDGGTEVVAAKAGKGSATLSMAYAGAVFADSCLRAKNGEAGVVECTYVESNVTDARFFASKVTLGKEGVETIHGLGELTPYEKAGLDGMMAELNDSINKGVEFAKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N263</accession>
    <name>C1N263_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_70124</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062036.1">
        <property type="nucleotide sequence ID" value="XM_003061990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N263"/>
    <dbReference type="GeneID" id="9687675"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70124"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="176" mass="19597" checksum="BFC81E74172764F2" modified="2009-05-26" version="1">MMRSATIAPTTTFAATRVRPPPFSSPRARVALVAPAGEEKRKMLTDEGNTAIQHRRRPPPPPPPPPLPFSLPRARPDPFAARAHPSPSRRRARSVRSPTDVSSPPPRRPVHPPVLLPSPPVGARARACAPRPQPRTPDARPRRRPARARIDPGDARVLTRRRRARARRERVARRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2I0</accession>
    <name>C1N2I0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51535</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062093.1">
        <property type="nucleotide sequence ID" value="XM_003062047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2I0"/>
    <dbReference type="STRING" id="564608.C1N2I0"/>
    <dbReference type="GeneID" id="9687532"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51535"/>
    <dbReference type="eggNOG" id="KOG1552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="446723at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="499" mass="51981" checksum="EFCC65DF931C7AD1" modified="2009-05-26" version="1">MPPAPSAPAVAAEDDDRGGGGGCECHCVETCAVGVVLARFGCAPSAMGSAFAFYPPNPPTYGVHDGVGFAHGRKVATYDDPRVQRAWGGVFNAFEVDLVRRASSSKGSDEDEMANVAVVSRGVAPDARCVLILAHGNALDLGTAAPFALEMHDALDVGVVAFDYTGYGPNVRGDASGWAGSDDGDVDATEKRARASAAKWKPSIEAAKADLIAVVDWVVTARRVRPERVVVVGQSVGSGPAVAYAAAAAGEKKRQKGSGAFYLTLVPIRPRWREGRYRHHPIGGLVLVSPLLSGLRVIAPYGGWCAPHQVCAPCDVFRNDRLASEIACPTLVVHGERDETIAASHGRGLHARLVGSAVNDDFAAPLWVPTAGHDDVVDLDRSSAFVARVRGFVDAVARRANRKSDGGGGGGGKGKGTEEQMTAVAPSRQRMAKPTPPAPRRDGGLLPAYLSAHPPLSIPTLGAFQRHLTPLNSTPTFACMERPGGAPVRVAPAPPDASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2T1</accession>
    <name>C1N2T1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_28857</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062139.1">
        <property type="nucleotide sequence ID" value="XM_003062093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2T1"/>
    <dbReference type="STRING" id="564608.C1N2T1"/>
    <dbReference type="GeneID" id="9687578"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_28857"/>
    <dbReference type="eggNOG" id="ENOG502QTMX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTLYADH"/>
    <dbReference type="OrthoDB" id="1386367at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053022">
        <property type="entry name" value="Chloroplast_translocon_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007452">
        <property type="entry name" value="TamB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34457">
        <property type="entry name" value="EMBRYO DEFECTIVE 2410"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34457:SF3">
        <property type="entry name" value="PROTEIN TIC236, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04357">
        <property type="entry name" value="TamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Translocation and assembly module TamB C-terminal" evidence="5">
        <location>
            <begin position="576"/>
            <end position="941"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="957" mass="100723" checksum="44896532E4EE352C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2T5</accession>
    <name>C1N2T5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_35527</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062141.1">
        <property type="nucleotide sequence ID" value="XM_003062095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2T5"/>
    <dbReference type="STRING" id="564608.C1N2T5"/>
    <dbReference type="GeneID" id="9687372"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35527"/>
    <dbReference type="eggNOG" id="KOG0079">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KMWGQPS"/>
    <dbReference type="OrthoDB" id="265044at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="190" mass="20917" checksum="9B1094A53DB62253" modified="2009-05-26" version="1">MSVTLRAKVAILGDRAVGKTAFTQMFHSKGKLFPKNYKLTGGMDVVVAPVPIEGTKAVVELYVCDVSGHEMFSDMMPILLENVNMVILVYDQSSRESFDKCASCLEALKAVPSNKGKAIRGVLVGNKYDLLRRRGVSVEEATRWAESRQLVFMETSALPPGKDIAAPFKWCANAFHESYEARLVQLDNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2T6</accession>
    <name>C1N2T6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">General transcription factor IIH subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_21068</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the GTF2H2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061932.1">
        <property type="nucleotide sequence ID" value="XM_003061886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2T6"/>
    <dbReference type="STRING" id="564608.C1N2T6"/>
    <dbReference type="GeneID" id="9687581"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21068"/>
    <dbReference type="eggNOG" id="KOG2807">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="INWVEVP"/>
    <dbReference type="OrthoDB" id="284275at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000015">
        <property type="entry name" value="General transcription factor IIH subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007198">
        <property type="entry name" value="Ssl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004595">
        <property type="entry name" value="TFIIH_C1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012170">
        <property type="entry name" value="TFIIH_SSL1/p44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00622">
        <property type="entry name" value="ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07975">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04056">
        <property type="entry name" value="Ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015919">
        <property type="entry name" value="TFIIH_SSL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01047">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="12">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR015919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR015919-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH53644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="404" mass="44860" checksum="AA44E0E3C839B078" modified="2009-05-26" version="1">MYGEPEDDDLAAEEQASSLRAFEKHYQSENTWEDLVEDESGMLRVTTGDKGYREKRRKIALAASNSHVCKGMIRFVYVVLDLSQAVNEEDMRPSRLAVISSLMYKFFREFFNQNPLSQLGLVVTRNGIAERVTELSGNPETHIAALKENLDAAGDMSIQNSLEQVHASLVQLPMYGSREVLFVVSALSTCDPGNVHTAIAAAKNAKIRVSVVSVAAEMHVCRRMTEETGGIFGVAQSQHHLEELLMAHAPPPPLNEESTKPSLVEMGFPQKRPLDKDAFFSGRGGDYVCPRCKSRVEELPSQCTVCKLTLVSSAHLARSYHHLFPVPPFTEGFGLDDEGKRHTSCFACYVDFEEGNESTSNENAPSVCPKCKKTFCFVCDVYIHEKLHNCPGCELVKFLAEEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N327</accession>
    <name>C1N327_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_52010</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062306.1">
        <property type="nucleotide sequence ID" value="XM_003062260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N327"/>
    <dbReference type="STRING" id="564608.C1N327"/>
    <dbReference type="GeneID" id="9687977"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52010"/>
    <dbReference type="eggNOG" id="ENOG502QRYX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FQKFECQ"/>
    <dbReference type="OrthoDB" id="550273at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="4">
        <location>
            <begin position="66"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="249"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="324" mass="33250" checksum="D32DEAD0B4AB47F0" modified="2009-05-26" version="1">MASLPAAAPSLSRAPALAPRAAAPASSSSRRAAARRRAVARAAAPSPDLATDATTTTTTTTRRDAAKRALRYATEGTYRGALASTSDRAAVEEAQVALEAFAAGTPLDRAVLAGRWRLLYTTASDVLSVIRLGRDVGVVDVGDVFQSFDDAGKIQNEIRLSVPFLLAPATRGKPGGVSLKVDADYRVVGDRTLSLVFNEAKVSEVRISDAVEAALAPALLPRGSLNRQVLLAIREFELKFPLRSALSSMGGGGGSDGDGDGDGAVGGGNDDAETRDASAARGGGGGGAPVGAYLISYVDEDTLVGRANGTGTFIFQREGDFEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3I9</accession>
    <name>C1N3I9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_52191</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062383.1">
        <property type="nucleotide sequence ID" value="XM_003062337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3I9"/>
    <dbReference type="STRING" id="564608.C1N3I9"/>
    <dbReference type="GeneID" id="9688062"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52191"/>
    <dbReference type="eggNOG" id="KOG2159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CEEREWL"/>
    <dbReference type="OrthoDB" id="445712at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CC tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000019">
        <property type="entry name" value="tRNA nucleotidyltransferase cca2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3090.10">
        <property type="entry name" value="cca-adding enzyme, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734:SF5">
        <property type="entry name" value="CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734">
        <property type="entry name" value="TRNA-NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly A polymerase head" evidence="6">
        <location>
            <begin position="169"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="729" mass="78886" checksum="C831A5B4BDCD6D5A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3N0</accession>
    <name>C1N3N0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_35904</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062643.1">
        <property type="nucleotide sequence ID" value="XM_003062597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3N0"/>
    <dbReference type="STRING" id="564608.C1N3N0"/>
    <dbReference type="GeneID" id="9687843"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35904"/>
    <dbReference type="eggNOG" id="KOG0900">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IHKRVIH"/>
    <dbReference type="OrthoDB" id="10248551at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.600:FF:000002">
        <property type="entry name" value="40S ribosomal protein S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_uS10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005729">
        <property type="entry name" value="Ribosomal_uS10_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01046">
        <property type="entry name" value="uS10_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="4">
        <location>
            <begin position="25"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="123" mass="13564" checksum="28FD0A30510402C4" modified="2009-05-26" version="1">MSAPYKAPGGKGEEGGEAARVHRIRITLTSKNVANLEKVCADLIRGAKEKRLKVKGPVRMPTKRLKLTVRKSPCGEGTNTWDRFELRIHKRLIDLHSPADVVKQITSISIEPGVEVEVTIVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4A0</accession>
    <name>C1N4A0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_21980</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062961.1">
        <property type="nucleotide sequence ID" value="XM_003062915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4A0"/>
    <dbReference type="STRING" id="564608.C1N4A0"/>
    <dbReference type="GeneID" id="9688195"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21980"/>
    <dbReference type="eggNOG" id="KOG2484">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VINRRDM"/>
    <dbReference type="OrthoDB" id="269151at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01856">
        <property type="entry name" value="YlqF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001189">
        <property type="entry name" value="DAR GTPase 3 chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019991">
        <property type="entry name" value="GTP-bd_ribosome_bgen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016478">
        <property type="entry name" value="GTPase_MTG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03596">
        <property type="entry name" value="GTPase_YlqF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782:SF5">
        <property type="entry name" value="DAR GTPASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006230">
        <property type="entry name" value="MG442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="4">
        <location>
            <begin position="132"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="66"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006230-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="337" mass="37066" checksum="AEED861D9DC4745F" modified="2009-05-26" version="1" fragment="single">SLLSSLQVRLVQWYPGHIAKAERALREQLRGVDAVVEVRDLRIPLATTHPEIPNWIGGKLRVLVLNRADMVSDGERQRWVAWFKKNGEKHVVLTDAKSGKGVNRVKEVALLVSEEVNAKRAAKGLMPRPVRTAIIGYPNVGKSALINRLTNSKACASAPRPGVTRNLRWVRVGGDLDLLDSPGVLPPRLADQAAATRLAMANDIGEASYLSSNVAAQLFDEMKTLPQWTTRKRFKLDAIPDAMTGEDFVIAVAEKMSSDDLERAGTRILIDFRSGALGAFCLEPAPRKGDDYADASEMGKPKRVVMDAPTEVKLGHGYYDARDEVELRELGADVDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4B4</accession>
    <name>C1N4B4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66718</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062759.1">
        <property type="nucleotide sequence ID" value="XM_003062713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4B4"/>
    <dbReference type="GeneID" id="9688199"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66718"/>
    <dbReference type="OMA" id="KFRIWRT"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="295" mass="31448" checksum="A7843F8307310A67" modified="2009-05-26" version="1">MTAEAGAKALDAILALTAPRRRDAATAFIPRATGIGGAGRRRRSVARVAGAVRRERSGDGGGEFDAAAGGARLRRAGADRAAGVAERARYARRGLRAAVAARDRGATRGVGRPRARDHGARGGRPRRRRRGRASDRGGGASHARARGVVGRRRRRRRVARRARAAPLRRDQGRPPVGRRRRGPRRRRRRGGAPAGPGDDSQGRGAVRGRLRSGDCPRDVPTRVLAVAAVGGCGDRGGLGRRREGGRGARRGRVERAARDVFDARDALAAAAATPRRVAGDRERRRPTVSETILLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4B9</accession>
    <name>C1N4B9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_52496</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062973.1">
        <property type="nucleotide sequence ID" value="XM_003062927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4B9"/>
    <dbReference type="GeneID" id="9688413"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52496"/>
    <dbReference type="eggNOG" id="ENOG502STCE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="425081at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="281" mass="29652" checksum="DE596D4CAA3AE184" modified="2009-05-26" version="1">MTSSSSSPPPPPVERELESVVVLDAVVARAGVDDAAPGAASADAERPPPSPPIFSAPHGVFLHRASALKVPEEWTSFLAEEFARACDGVAIAWSKDERVRSRAARDAVPGRIDPNCCDPASDASHPFGVLLRRHAAAHPGALHVDVHGRRDPEGDALVDIGRGDVDVGTGALRGASDDERSRAFAERVRRAVSRRLRAFLATTWGGDGDGDGFEVNDDPVLAGARADGMHTMSQRGVELGLVSVQLELSLRLRNALRADGDATRGFAHAVLAAWEECRSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4I4</accession>
    <name>C1N4I4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_42420</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062797.1">
        <property type="nucleotide sequence ID" value="XM_003062751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4I4"/>
    <dbReference type="STRING" id="564608.C1N4I4"/>
    <dbReference type="GeneID" id="9688237"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42420"/>
    <dbReference type="OMA" id="QRDECER"/>
    <dbReference type="OrthoDB" id="552102at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="232"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="345"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="564"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="624" mass="67349" checksum="BF142178BB1C85EA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5A2</accession>
    <name>C1N5A2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42593</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062931.1">
        <property type="nucleotide sequence ID" value="XM_003062885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5A2"/>
    <dbReference type="STRING" id="564608.C1N5A2"/>
    <dbReference type="GeneID" id="9688577"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42593"/>
    <dbReference type="eggNOG" id="ENOG502QU6A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ILCDVWG"/>
    <dbReference type="OrthoDB" id="426235at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF90">
        <property type="entry name" value="OS08G0542600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="404" mass="42272" checksum="3AC994AAE474B29B" modified="2009-05-26" version="1">MSRASTPSLAAAAASSPSPSSPSPSSRGGGDHRGSHHHHPPRRFATTPLTGVRDLVREGKTIWLLDQFGVLHDGKTAYPAAIHATKRLYDAGAKLYVISNSSRRSAKTLAKLEPMGFDPAWFAGAITSGEMTWRALEARDAFEGSAEADARGPKPFAGDKVLHFTWSERGSIALDGLGLTTVTSPDDADFIVAHGTEAVNGAGDTDAQRAAGIELKAMEDMRGLLRRAARRNIPMMVANPDYVTVGGEGGALMKMPGTLARWYEEALESESESDGEGEDGTPTGTGTGGVVHLMGKPNKIIYDEVFRMASDGGGGARRTISMENVVAVGDSLEHDVIGAQNAGCDVVFVCGGIHADDLGMDPAALTGDGVGDGAAVPFPPAEAIERVARAHDAAPTYAVPVFKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5A9</accession>
    <name>C1N5A9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein CUP999</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CUP999</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_70684</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063139.1">
        <property type="nucleotide sequence ID" value="XM_003063093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5A9"/>
    <dbReference type="STRING" id="564608.C1N5A9"/>
    <dbReference type="GeneID" id="9688376"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70684"/>
    <dbReference type="eggNOG" id="ENOG502RXQI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ERLICHD"/>
    <dbReference type="OrthoDB" id="2016911at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35699">
        <property type="entry name" value="F2J10.10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35699:SF1">
        <property type="entry name" value="F2J10.10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="236" mass="24853" checksum="C4A2696BF1AFBD1D" modified="2009-05-26" version="1">MAFAAPTVALAPRAARARGVASVASARRVAVSAPATAKTTTTRSSRLAIRVDRWPRRRATTTTTTTTTTTTTRATSGDDDVASDGDADATSSAFAEELKRRRAAEENGDETGASARGGGGGGSDKWAGGADRDAPRFAPRDDGARGVETEQLKRSRSINNEGLDGFPSRAGELVKLGLTSFLSFGPLIAIFSVVFVASYLLLGSDFIHGGEATTYRYVPPEVLLNEETVDRMVPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5S3</accession>
    <name>C1N5S3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48807</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063206.1">
        <property type="nucleotide sequence ID" value="XM_003063160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5S3"/>
    <dbReference type="STRING" id="564608.C1N5S3"/>
    <dbReference type="GeneID" id="9688854"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48807"/>
    <dbReference type="OMA" id="WARCHTA"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051647">
        <property type="entry name" value="Mediator_comp_sub12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46007:SF8">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46007">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="641"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="411"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="703" mass="68681" checksum="EF1774539198BC45" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5V4</accession>
    <name>C1N5V4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="11">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MICPUCDRAFT_36311</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="11"/>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063430.1">
        <property type="nucleotide sequence ID" value="XM_003063384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5V4"/>
    <dbReference type="STRING" id="564608.C1N5V4"/>
    <dbReference type="GeneID" id="9688662"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36311"/>
    <dbReference type="eggNOG" id="ENOG502QV7D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RFGQRNF"/>
    <dbReference type="OrthoDB" id="1718875at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008760">
        <property type="term" value="F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019277">
        <property type="term" value="P:UDP-N-acetylgalactosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01555">
        <property type="entry name" value="UdpNAET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="entry name" value="Enolpyruvate transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050068">
        <property type="entry name" value="MurA_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005750">
        <property type="entry name" value="UDP_GlcNAc_COvinyl_MurA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43783">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43783:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Enolpyruvate transferase" evidence="17">
        <location>
            <begin position="96"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="47"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="402"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00039754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH52566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="588" mass="58961" checksum="D516B0D3C4DD7FA7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N626</accession>
    <name>C1N626_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_48843</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM192 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063461.1">
        <property type="nucleotide sequence ID" value="XM_003063415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N626"/>
    <dbReference type="GeneID" id="9688703"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48843"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029399">
        <property type="entry name" value="TMEM192"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31592">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31592:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="430"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="297"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="430"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="456"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="469"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="511" mass="53806" checksum="94B8CB5E4F3A3C36" modified="2009-05-26" version="1">MASLSPMTAAMSRGFARDPPPPSLAEPLLPRSTPPTGHARRRRDDDDDDASSDSNAVARGAALPLTPPRRDAAFGDVAVSAASDAETDDGFVPWADATPFAYVALVLCVALAAARLGDVRDARSPALLSMALLALAGAMQPLLCASLTKARRAGYLDFYLSSRRAFRAPFAIASVGTATACLASILLGVFVDPEDGASASTLIRVPDRIARALLPGYQTRAPSPFVVASATAFVAFGFECVALLIALGVIIARTRRHRRAGTPPDAKSALNPPNAAGDDDDDDETGRARGGWSPSFDFKRGVRRGETTESVSDAQAELNRYMCDQVSELGREVLRLRRVVARRETMARGVGHARAMAASAATTSQVAAAAAGDATPAEAVTRAAHAAALNLVQAELKATRAELARREREASRLRELDFARSEEATRLRRALEEKERRAEEAKSAGAAEEKEEISREAGPGPASGEAPAPAVPPPPADADPPVSPSKKKTYPEPKRVTDAVAKMNDAFGMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6I9</accession>
    <name>C1N6I9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_42879</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063749.1">
        <property type="nucleotide sequence ID" value="XM_003063703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6I9"/>
    <dbReference type="STRING" id="564608.C1N6I9"/>
    <dbReference type="GeneID" id="9688999"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42879"/>
    <dbReference type="OrthoDB" id="513770at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="entry name" value="YqgF/RNase H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025086">
        <property type="entry name" value="SDE2/SF3A3_SAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13297">
        <property type="entry name" value="SDE2_2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDE2/SF3A3 SAP" evidence="2">
        <location>
            <begin position="184"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="296" mass="31928" checksum="58392ADF53AA1928" modified="2009-05-26" version="1">MATAAVGAAAARGATPSPRRRRQRPCSEEDNTPTRWRWRRVVVVADATRVRAGKRSDWDLLHDELRASSSSSSSSHRVALGVDYGRRRTGLAVSSTGASPIPLAVIPSVPPHELVRAVVDAARRERATEIIVGLPTQPAASEARRRTATGRARSCSKKNSTHAAAPAVVELPSAWRATDSTTTPFEDAEAVAEALGMDELRDGLTSLGMKAGGDERERAARAWALIAAGGDLRAVPDGMFRGGAVGKRERIDENMRAIRGGRRRRRRVARPRRLPVRRDAHLERRGGGGARVREGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6R8</accession>
    <name>C1N6R8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53413</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063600.1">
        <property type="nucleotide sequence ID" value="XM_003063554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6R8"/>
    <dbReference type="STRING" id="564608.C1N6R8"/>
    <dbReference type="GeneID" id="9689041"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53413"/>
    <dbReference type="eggNOG" id="ENOG502QSXW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31801">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31801:SF1">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="845"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="751"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="759"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="863" mass="92688" checksum="47948E5EFF9B1052" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7A5</accession>
    <name>C1N7A5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_36663</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VPS53 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063863.1">
        <property type="nucleotide sequence ID" value="XM_003063817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7A5"/>
    <dbReference type="STRING" id="564608.C1N7A5"/>
    <dbReference type="GeneID" id="9689145"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36663"/>
    <dbReference type="eggNOG" id="KOG2180">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YKFAEAK"/>
    <dbReference type="OrthoDB" id="10261632at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039766">
        <property type="entry name" value="Vps53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031745">
        <property type="entry name" value="Vps53_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007234">
        <property type="entry name" value="Vps53_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16854">
        <property type="entry name" value="VPS53_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04100">
        <property type="entry name" value="Vps53_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps53 N-terminal" evidence="9">
        <location>
            <begin position="28"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Vps53 C-terminal" evidence="10">
        <location>
            <begin position="687"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="354"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="818"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="916"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="78"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="833"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="917"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH52236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="939" mass="99476" checksum="D7C93C7217DE0BC5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7H4</accession>
    <name>C1N7H4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_53695</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063737.1">
        <property type="nucleotide sequence ID" value="XM_003063691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7H4"/>
    <dbReference type="GeneID" id="9689340"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53695"/>
    <dbReference type="eggNOG" id="ENOG502QVAR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="423069at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="4">
        <location>
            <begin position="102"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="264" mass="29036" checksum="4C15262E0B914B7B" modified="2009-05-26" version="1">MATTTHASAMAAATRARARGTTPSTSAPPTSASSRARPLAAARRRRDGATAAPTPHTIDYSTRRRRGYTSTTTLRATTTTTTTTAASAYEAFPEKWDVLRLAAEQRRGVGHSEEDRAAMEAAIDALVAAAAKRESDPHPATSPKRLTARWRLVWTSEKETLFLLEKFTAEAYQVIDVIGRKLANEVVFKGNGSVFVVDSAMNIASESKCAFDFIGARYEFDNPFKWVLRLPPVGRGWFENVYVDETMRCARDSRGDTLVVVRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7K0</accession>
    <name>C1N7K0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53724</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063915.1">
        <property type="nucleotide sequence ID" value="XM_003063869.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9689188"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53724"/>
    <dbReference type="OMA" id="WARSAFH"/>
    <dbReference type="OrthoDB" id="47388at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030572">
        <property type="term" value="F:phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00138">
        <property type="entry name" value="PLDc_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248:SF22">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="419"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="485"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="856" mass="90213" checksum="E010ECB969AA492B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7K3</accession>
    <name>C1N7K3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_49037</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063917.1">
        <property type="nucleotide sequence ID" value="XM_003063871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7K3"/>
    <dbReference type="STRING" id="564608.C1N7K3"/>
    <dbReference type="GeneID" id="9689555"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49037"/>
    <dbReference type="eggNOG" id="KOG0020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YMLQETS"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000005">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000005">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.790:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910781" evidence="7">
        <location>
            <begin position="27"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="8">
        <location>
            <begin position="70"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="260"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="472"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="775"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="260"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="474"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="780"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="145"/>
            <end position="146"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="165"/>
            <end position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="820" mass="92782" checksum="F0E6C6459E5B3F93" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Q0</accession>
    <name>C1N7Q0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Highly cold-shock DNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_53785</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064131.1">
        <property type="nucleotide sequence ID" value="XM_003064085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Q0"/>
    <dbReference type="STRING" id="564608.C1N7Q0"/>
    <dbReference type="GeneID" id="9689572"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53785"/>
    <dbReference type="eggNOG" id="KOG2494">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GQTGHMA"/>
    <dbReference type="OrthoDB" id="422005at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12675">
        <property type="entry name" value="MUSCLEBLIND-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12675:SF12">
        <property type="entry name" value="PROTEIN MUSCLEBLIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CSD" evidence="8">
        <location>
            <begin position="74"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="122"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="272"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="273"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="290"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="325" mass="34929" checksum="D0E2C8D8EB86E639" modified="2009-05-26" version="1">MGSPSRSRSPPNRSRSRSPAKDSPTRGGGGSPPPARDRSRSRSRSRGRSRSRSRSPPRGGDRSRSPPRGGSGARKSGIAGRWNDRGFGFITPDGGGEDVFCHFSAIKDGNMLSEGSRVDYDESFDDRKGKPRAENVTGGIQGNDRGPPREAGICRDFQRGNCTRGPGCRFSHGCVIARDRASERSTAAIHSRSLSHLEFFSNRMNFPPRPAVAIDRLTPPPPPPLAPLLGFSDDRGGGGGYGGGGYGGGGRSNECFDFQKGRCTRGDSCRFSHGGGGGGGGGGGGYGGGYDRDRYDDRDRDRYDDRRGGDRYDSYDRYDRSYDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Z4</accession>
    <name>C1N7Z4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.258</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_3334</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29527"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="Rhea" id="RHEA-COMP:19517"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="ChEBI" id="CHEBI:132516"/>
            <dbReference type="EC" id="2.4.1.258"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:29528"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.258" evidence="3"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063992.1">
        <property type="nucleotide sequence ID" value="XM_003063946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Z4"/>
    <dbReference type="STRING" id="564608.C1N7Z4"/>
    <dbReference type="GeneID" id="9689621"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3334"/>
    <dbReference type="eggNOG" id="KOG2762">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PERYGIH"/>
    <dbReference type="OrthoDB" id="20028at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052925">
        <property type="term" value="F:dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007873">
        <property type="entry name" value="Glycosyltransferase_ALG3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646:SF0">
        <property type="entry name" value="DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646">
        <property type="entry name" value="NOT56 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05208">
        <property type="entry name" value="ALG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910783" description="dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH51614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="400" mass="44055" checksum="380CEAAEBCF0289B" modified="2009-05-26" version="1" fragment="single">VARVLVVLDALLSVAIVRRVAYTNIDWNAYMGEARGYASGERDYAKLRGDTGPLVYPAGFLYLYDALRRVTDDGADVRRAQMIFVVVYAAHQAAAMAVTVKARVVPPWALSLLCVSKRIHSVFALRMFNDGVCSLVAWVAIWLAQSKRFVAAAVALSVAASVKMNALLFLPPFLVLLVGHERVSTACVAVGAFVGVQVVVGWPFLSTYPREYVGRAFELGRKFTYEWTVNWKFVSIETFSSDAFSLGLLLAHVAILFAFAHARWYRRGGGFFPAFFVDFFERARTDAAASKRLKSLTAADVVCAMAEGNFIGIVFARSLHYQFYAWYFHSLPLLLWSISSNGSRRGGKGGGRLRRALAVAARVGAMGAIEWCWNVYPSTPTSSLVLFATHAALLMSLWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N862</accession>
    <name>C1N862_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_23095</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064211.1">
        <property type="nucleotide sequence ID" value="XM_003064165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N862"/>
    <dbReference type="STRING" id="564608.C1N862"/>
    <dbReference type="GeneID" id="9689470"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23095"/>
    <dbReference type="eggNOG" id="KOG0776">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GKQMRPM"/>
    <dbReference type="OrthoDB" id="9927103at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010236">
        <property type="term" value="P:plastoquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02749">
        <property type="entry name" value="prenyl_cyano"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF69">
        <property type="entry name" value="ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="324" mass="35627" checksum="FBD7A47CB64FE25A" modified="2009-05-26" version="1">MDIDAITAPVMADMEQMRMNLRDIVGRKNPLLLAAADQIFGAGGKRLRPVLVFLVARSTAQLMDMPEITDRQRRLAEITEMIHTASLVHDDVLDDCDTRRGAQTIHTLYGTRVAILAGDFLFAQSSWYLANLDNLEVIKLISQVIADFADGEISQAGALFNCDVTLEGYLEKSHNKTASLIAASCKSAAVFSEVSEDIKVDMYEYGKHLGLAFQVVDDILDFTQTEEQLGKPQGQDLASGNLTAPTIFALRRDASLRALVESQFKTEGDLEKAIAIVNEVGIEDARTLAREEADMALAALKGLPEGEAKQSLVDMVQYILERIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9T9</accession>
    <name>C1N9T9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_67762</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064673.1">
        <property type="nucleotide sequence ID" value="XM_003064627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9T9"/>
    <dbReference type="GeneID" id="9690114"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67762"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="390" mass="43573" checksum="5EDD769B752067A0" modified="2009-05-26" version="1">MSPSRNSGWSTNFSNAAIASSSRFCAAFSRFEYTPAYIPFSNRSCSKRFSSSSPLATDLSLFSRSSRSVIATSSRSKASRAALVSSRFPSANRRPRSRSLVAMPRSLPTHSMKNALHPRHAYVSEKKAQVPARMRSFPDRFFSVTSFAHRFVASTLLQNPCRAHSRSHTSSPSVRLDRMRRSHWRSAHTETKSRWAITRSQISSGRRGRCVVVVVVVVGGGGDIARARFFAIPAAAASRVFPPSPRPLLGRGVEQPIERRALGVDAVEDLPSKLRGEPNRVVAHGEALARVSVGRRARGRARRRLRARGLDERGLDERGRARLRRSRSRALRHGRKTARKGVRAVGEGIDRKIWTLSRLRARRLRFILSEGSIARRRRTPERPATVVPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Z2</accession>
    <name>C1N9Z2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_67790</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064820.1">
        <property type="nucleotide sequence ID" value="XM_003064774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Z2"/>
    <dbReference type="STRING" id="564608.C1N9Z2"/>
    <dbReference type="GeneID" id="9690261"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67790"/>
    <dbReference type="eggNOG" id="KOG1860">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NWRENET"/>
    <dbReference type="OrthoDB" id="264795at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="2">
        <location>
            <begin position="207"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="635" mass="68027" checksum="C35792D900242765" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAH2</accession>
    <name>C1NAH2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54905</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064959.1">
        <property type="nucleotide sequence ID" value="XM_003064913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAH2"/>
    <dbReference type="GeneID" id="9690400"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54905"/>
    <dbReference type="OrthoDB" id="10351758at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH50939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="357" mass="40357" checksum="1C5EF3491E1896AC" modified="2009-05-26" version="1">MARTKCTPRDIGGVYKAYRSGPANIPVYVFPGGTRNWSTVAPTMRSLARTKVIYVTRDELSGLKRKPTSMSALYGYERRVRDIEAGDLSATDGTRVLQGVPTLPVNFTEAQLREYQNACANLKSSPDYESFRAALITGEINAKKALGFMHLAADAKSTEVEKDAYLTVARFIATAKHRMRDSKDFTGELPDVPEETRRHVMKLIGECGFTGSLRSAFELDFVRTKLRVVGAKGQNMFINVLRREGRTDAVFCPGYATTKAFAELVGLDKKARDYAKRKGKECRDRFHPPTEADRYRPWTCRPRIQHHRELVPYVAELIHGYYVVYLTDIDTQWHGDVGEDEVMWAATEVKGKKRGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAI7</accession>
    <name>C1NAI7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66090</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064915.1">
        <property type="nucleotide sequence ID" value="XM_003064869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAI7"/>
    <dbReference type="GeneID" id="9690409"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66090"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="85" mass="10153" checksum="244FBCB6A9B296CD" modified="2009-05-26" version="1">MARALVAMVWVRVFLRLEEVSQPLFQPLFEPFFKTSIPRLYFVPSQIVVFVIHYALFLVFVRPLYTFAEENIYDELFKFLTMIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRB8</accession>
    <name>C1KRB8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS9c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">30S ribosomal protein S9, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MicpuC_chl17</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="7"/>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRB8"/>
    <dbReference type="STRING" id="564608.C1KRB8"/>
    <dbReference type="OMA" id="IQINQVD"/>
    <dbReference type="OrthoDB" id="10254627at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_uS9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001099">
        <property type="entry name" value="PRK00132.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACO50750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="128" mass="14362" checksum="1376A50117111C2F" modified="2009-05-26" version="1">MQQIWSATGRRKRASAQVRIASPGTGTIQINQVDAQVYLQGKYPTILKPLQLFQLEEKCDVFIQTTGGGLTGQADAIRLGCARALCLMDQTYRSELKAQGYLTRNALKKERKKYGLKKARKAPQFSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGP4</accession>
    <name>C1MGP4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49888</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054813.1">
        <property type="nucleotide sequence ID" value="XM_003054767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGP4"/>
    <dbReference type="STRING" id="564608.C1MGP4"/>
    <dbReference type="GeneID" id="9680707"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49888"/>
    <dbReference type="OMA" id="NRAPQIM"/>
    <dbReference type="OrthoDB" id="202195at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33417">
        <property type="entry name" value="G-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="98" mass="11200" checksum="5C7E77756F8DC808" modified="2009-05-26" version="1">MSRVAAQKTWQQIWIRPEVFPIVAAIGSAGTLCVFFCGRQISSSPGFRTFKDARKNECIPEDAKRVKEGISWRENLVRRTVRGMNPQIFPGLNDWMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHF4</accession>
    <name>C1MHF4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">G2-like myb family transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_61323</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054945.1">
        <property type="nucleotide sequence ID" value="XM_003054899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHF4"/>
    <dbReference type="STRING" id="564608.C1MHF4"/>
    <dbReference type="GeneID" id="9680330"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61323"/>
    <dbReference type="eggNOG" id="ENOG502QXMH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="551907at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000007">
        <property type="entry name" value="Two-component response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025756">
        <property type="entry name" value="Myb_CC_LHEQLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046955">
        <property type="entry name" value="PHR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31499:SF79">
        <property type="entry name" value="HTH MYB-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31499">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR PHL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14379">
        <property type="entry name" value="Myb_CC_LHEQLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="149"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="205"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="427" mass="45316" checksum="5EC4D9FAD8374281" modified="2009-05-26" version="1">MTRMSGIEDDSFSYSFLLISGQLRDPTRLTPRPQTSSAPLGAGGGAAAASGMNTSGTFWPSDLDLDLESSDFLDSLLLGGEMMTTQQQHHHAGDERLGHGPVPLGARAAGEDHDPRVVLAERDAGDGLLPRALADERREPVARAVVASNNNKQRLRWTPELHKMFVDAVKRLGGLDLATPKGIMQLMDVEGMSIQHVKSHLQKYRLQDSGGGASEFRVSPDASASGKRPRSEEDDAGGNGKDGNNSAGKTRRRPSAAERSAARLRAAEEKAREERDAARSMAAAAAAAAAAAVERQNVELALLTGDAAGARDALEMSSHHAASHVGGAYDDVLDLVAGPGESGDGDGAWGDVLHDHAIVGAAGDDVGLVDDVGSDPEAAAAMLKQLELQKKLHEHLMSQRRLQQQVEAHGVYLETILDQQKRRRGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHQ7</accession>
    <name>C1MHQ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50287</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055536.1">
        <property type="nucleotide sequence ID" value="XM_003055490.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9680598"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50287"/>
    <dbReference type="OMA" id="ESYPRVE"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025883">
        <property type="entry name" value="Cadherin-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12733">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910250" evidence="2">
        <location>
            <begin position="26"/>
            <end position="2035"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin-like beta-sandwich-like" evidence="3">
        <location>
            <begin position="209"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin-like beta-sandwich-like" evidence="3">
        <location>
            <begin position="300"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin-like beta-sandwich-like" evidence="3">
        <location>
            <begin position="449"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin-like beta-sandwich-like" evidence="3">
        <location>
            <begin position="569"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin-like beta-sandwich-like" evidence="3">
        <location>
            <begin position="664"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin-like beta-sandwich-like" evidence="3">
        <location>
            <begin position="781"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin-like beta-sandwich-like" evidence="3">
        <location>
            <begin position="993"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin-like beta-sandwich-like" evidence="3">
        <location>
            <begin position="1564"/>
            <end position="1647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1676"/>
            <end position="1695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2035" mass="216615" checksum="B721FA19D2A4E273" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHT7</accession>
    <name>C1MHT7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_12811</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055012.1">
        <property type="nucleotide sequence ID" value="XM_003054966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHT7"/>
    <dbReference type="GeneID" id="9680305"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12811"/>
    <dbReference type="eggNOG" id="KOG2632">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SIHRTAN"/>
    <dbReference type="OrthoDB" id="10257275at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF1">
        <property type="entry name" value="RHOMBOID PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="9">
        <location>
            <begin position="55"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="231" mass="24324" checksum="91134864922104E7" modified="2009-05-26" version="1" fragment="single">MDAHGARAGDWYSSLPFGTRGVFTICVASYVLCVLVGFDDFARACVAPRHVLATGEVYRALTAPFFHGSLLHLALNMTAFVGTASGLERSLGTTQFALIVLLFALVAAAYHVALATAAALVGFTGAPMECAIGLSGIIFGLIVVDTHLSAIERRSVFGFFDVPSGWYPLGLLLFIQVIAPAVSFLGHAAGLLAGLTYVRGYLNPVLPSPAAIESFEAWPAMAAATRRRGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI33</accession>
    <name>C1MI33_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_50418</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055060.1">
        <property type="nucleotide sequence ID" value="XM_003055014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI33"/>
    <dbReference type="GeneID" id="9681164"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50418"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032053">
        <property type="entry name" value="Ribosomal_mS34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28589">
        <property type="entry name" value="28S RIBOSOMAL PROTEIN S34, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28589:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16053">
        <property type="entry name" value="MRP-S34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="75" mass="8703" checksum="BC34EBC80B1C3B33" modified="2009-05-26" version="1">MVKTLPDWGVGAKVAKGKWKHCGAENSFWTITRVRPRTSRSGKVWGNLTWKGEEKEDKLDVRIPHATRTTSRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI73</accession>
    <name>C1MI73_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50462</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055619.1">
        <property type="nucleotide sequence ID" value="XM_003055573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI73"/>
    <dbReference type="GeneID" id="9680204"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50462"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="195" mass="21329" checksum="F332C4390611F80B" modified="2009-05-26" version="1">MILARPRLALFALPVSPPSRRRRVAVAPLAASKKKKKQQPSDVGDSQDPVPVVEPSRTTKKEHWVEDSEDDGPLLDVDAGAKPRSVRGKNKKPVKTTASPAQKRAVTTPYGGRRATRPLRYGAVKIDTTRPTQVPGLVSRGSSWVSINCAFEDFPFDDFVDFVASVNDAVSETMASKVDASAERKDDDLNEDDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIG3</accession>
    <name>C1MIG3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46336</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055125.1">
        <property type="nucleotide sequence ID" value="XM_003055079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIG3"/>
    <dbReference type="GeneID" id="9680432"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46336"/>
    <dbReference type="eggNOG" id="KOG1437">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CPNDDAF"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050839">
        <property type="term" value="F:cell adhesion molecule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="48"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="177" mass="18044" checksum="CBC828196F46DC59" modified="2009-05-26" version="1">MAFALSKTASLVATPKASSKIARRGAVVVRAEKVAHGKGGEEGGRSFANDAFGMVAKNANYGLFAAAVTKGGHEGTMTSPGPITVFCPNDDAFGDLCQKIGVSKMDLMNDPRIPAIVGTHIVQGALTLADMEGKTLTTMAGNSITVSGGAVNGVSFKKNDIKVDNGIVHAVNAVISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ67</accession>
    <name>C1MJ67_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50829</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055780.1">
        <property type="nucleotide sequence ID" value="XM_003055734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ67"/>
    <dbReference type="GeneID" id="9680288"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50829"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH61032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="142" mass="14944" checksum="398BE92342F747F8" modified="2009-05-26" version="1">MWRKGHTRPGATEPVTLCNACGILYKRGWFCAHCEHVYRKPDDDPVDAPAWIGCDHCDGWAHYDCELRHAPEAVLPPPPPPPPAMGGEEEGAEDAAPGGADVGENADAAAAAAAAPETETVSVAGLLTCVLYTGPHTTAFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ77</accession>
    <name>C1MJ77_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoenolpyruvate carboxylase</fullName>
            <ecNumber evidence="4">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_31189</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>oxaloacetate + phosphate = phosphoenolpyruvate + hydrogencarbonate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="4"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055786.1">
        <property type="nucleotide sequence ID" value="XM_003055740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ77"/>
    <dbReference type="STRING" id="564608.C1MJ77"/>
    <dbReference type="GeneID" id="9680445"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31189"/>
    <dbReference type="eggNOG" id="ENOG502QPVS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RANYEDT"/>
    <dbReference type="OrthoDB" id="1365747at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.90:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.90">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000584">
        <property type="entry name" value="PRK00009.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523:SF33">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="10">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH61038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="991" mass="111195" checksum="5DCE4D79BCA95010" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJS5</accession>
    <name>C1MJS5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_38361</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056262.1">
        <property type="nucleotide sequence ID" value="XM_003056216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJS5"/>
    <dbReference type="GeneID" id="9681283"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38361"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="669"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="706"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="786"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="920"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="930"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="962"/>
            <end position="971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="971" mass="107811" checksum="18B900B84C956BA4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJX2</accession>
    <name>C1MJX2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_64114</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055895.1">
        <property type="nucleotide sequence ID" value="XM_003055849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJX2"/>
    <dbReference type="GeneID" id="9681649"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64114"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="337" mass="37315" checksum="0DACC4337767CC73" modified="2009-05-26" version="1">MRARRARREDAAGSGRDGDRGGRDDAATADAAAAREDDDDDVGLFREWRRAMTAPREDQEAFGRARAITRVRPRLSPSIHSSIASVSPPRRRWRAHPTARRMEDVHGALVLIFILFAFVMDLWRHPFTRVTLRLQQNFLTCFVVNVVALSLPLLRARAGIAPATRPALVRATYVVFACTMTGLIAHVGTTITRPVPIKYRYCFNAYVALFTQLAWDTPRLPRNASASMSMPRIVATIPTFMARVGIYIRWNGRGPYRCNLLGVCSGTPGPNHLGFPTTWLGCLSDVSVTAFVMTLAEAKLALSWRLWRRQVRRQEDAASASASECHRGGGGGARGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJY5</accession>
    <name>C1MJY5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55149</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056294.1">
        <property type="nucleotide sequence ID" value="XM_003056248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJY5"/>
    <dbReference type="GeneID" id="9681904"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55149"/>
    <dbReference type="OMA" id="CERERSY"/>
    <dbReference type="OrthoDB" id="10610177at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="598"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="866"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="913" mass="101708" checksum="871F3038290F219A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKC2</accession>
    <name>C1MKC2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_14046</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055969.1">
        <property type="nucleotide sequence ID" value="XM_003055923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKC2"/>
    <dbReference type="STRING" id="564608.C1MKC2"/>
    <dbReference type="GeneID" id="9681485"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14046"/>
    <dbReference type="eggNOG" id="KOG0737">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTNICVL"/>
    <dbReference type="OrthoDB" id="10254455at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000538">
        <property type="entry name" value="ATPase family AAA domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051701">
        <property type="entry name" value="Mito_OM_Translocase_MSP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644:SF3">
        <property type="entry name" value="FI08533P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="120"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="327" mass="36373" checksum="C9024229EEA25CF6" modified="2009-05-26" version="1" fragment="single">MAGQRQREPGMLPDIIFSLAMLAISVIPLHFFLKQLDPTRADREAAAKKKKLIARRLGRPDIVTNQFEDVIAGDVVNPDSITTTFAQIGGLEETKRALQEIVILPLLRPELFKSGNLLRPVKGCMLYGPPGTGKTMLAKALAKECDACFINVRASTLQSKWFGDANKLVAAVFSLAWKLQPSIIFIDEVDSFLGSRKTNEHEASTSMKTEFMTMWDGFQTNEHARVMVLAATNRPWEVDDAILRRLPRSFEVALPDKVNRIEILKVFLRDENVESGFFGMNETSPVTKIAAATERYSGSDLEELCKAAAYGPVRDVLAAEQRARTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKD2</accession>
    <name>C1MKD2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_49418</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056366.1">
        <property type="nucleotide sequence ID" value="XM_003056320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKD2"/>
    <dbReference type="STRING" id="564608.C1MKD2"/>
    <dbReference type="GeneID" id="9681327"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49418"/>
    <dbReference type="eggNOG" id="KOG2484">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FKLDGLW"/>
    <dbReference type="OrthoDB" id="444945at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051239">
        <property type="term" value="P:regulation of multicellular organismal process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04178">
        <property type="entry name" value="Nucleostemin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1580.10:FF:000002">
        <property type="entry name" value="Guanine nucleotide-binding protein-like 3 (nucleolar)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000571">
        <property type="entry name" value="Guanine nucleotide-binding protein-like NSN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014813">
        <property type="entry name" value="Gnl3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF30">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08701">
        <property type="entry name" value="GN3L_Grn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="7">
        <location>
            <begin position="151"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="504"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="605" mass="66881" checksum="DFFA7E9D814E8504" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKK7</accession>
    <name>C1MKK7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55373</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056012.1">
        <property type="nucleotide sequence ID" value="XM_003055966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKK7"/>
    <dbReference type="GeneID" id="9681344"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55373"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="618" mass="64027" checksum="2D69B2E63154FA94" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKY8</accession>
    <name>C1MKY8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_25020</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056079.1">
        <property type="nucleotide sequence ID" value="XM_003056033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKY8"/>
    <dbReference type="STRING" id="564608.C1MKY8"/>
    <dbReference type="GeneID" id="9681990"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25020"/>
    <dbReference type="eggNOG" id="KOG0346">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NASEQCV"/>
    <dbReference type="OrthoDB" id="1191041at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF21">
        <property type="entry name" value="DEAD-BOX HELICASE 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="13">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="38"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="267"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="535"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="544"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="583"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH59455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="598" mass="66002" checksum="A2CC65401E8E3184" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLI9</accession>
    <name>C1MLI9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ly 5'-AMP-activated protein kinase beta-1 subunit-related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BAMPK</name>
        <name evidence="2" type="ORF">MICPUCDRAFT_55729</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056174.1">
        <property type="nucleotide sequence ID" value="XM_003056128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLI9"/>
    <dbReference type="STRING" id="564608.C1MLI9"/>
    <dbReference type="GeneID" id="9682040"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55729"/>
    <dbReference type="eggNOG" id="KOG1616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="531008at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47342">
        <property type="entry name" value="PROTEIN PTST, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47342:SF1">
        <property type="entry name" value="PROTEIN PTST, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AMP-activated protein kinase glycogen-binding" evidence="1">
        <location>
            <begin position="303"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="383" mass="42308" checksum="AB32A44E8B0BB954" modified="2009-05-26" version="1">MTSEALTSSHSVLPIFKRHSPASKILARYSLAEPSSSLSARCASLPVTHRTPNRCRQRCRLAPSEVTFAIGRQLQTSGQVCLANTCTKNRRAYRNNLVAYCVTDENTSDISRPDSDTFKKRVAAAAAALRSGQANESRRKTISFLDQASENGSTENVPMRVGKVKLPSDKKSTKSDLLTPLSENEEQMAASQRRLFDQMVTLRTRLNERLAASNKFAMFLESTLATRDKDIKHANERLVAALLEIESLKHIAIEAVEAAESESKTKEQVVARLDTLTKRLDLMHSALRRDVKNIDAACIKCVPIRWVGMASDIRIMGSFDNWTKGIAMSPEFIEGGNNVFVADLMLTSGTYEIKFVVDGIWQTAPEWATTGEGLGANNLIVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLS5</accession>
    <name>C1MLS5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_56252</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057273.1">
        <property type="nucleotide sequence ID" value="XM_003057227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLS5"/>
    <dbReference type="STRING" id="564608.C1MLS5"/>
    <dbReference type="MEROPS" id="T03.025"/>
    <dbReference type="GeneID" id="9682252"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56252"/>
    <dbReference type="eggNOG" id="KOG2410">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EGNMVSY"/>
    <dbReference type="OrthoDB" id="2015213at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052896">
        <property type="entry name" value="GGT-like_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43881">
        <property type="entry name" value="GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43881:SF1">
        <property type="entry name" value="GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="594" mass="61451" checksum="FB12EDCBF0464A0B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM02</accession>
    <name>C1MM02_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56350</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057309.1">
        <property type="nucleotide sequence ID" value="XM_003057263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM02"/>
    <dbReference type="GeneID" id="9682748"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56350"/>
    <dbReference type="OrthoDB" id="10503284at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="104" mass="11213" checksum="F1EFDAAE8A4E5AF5" modified="2009-05-26" version="1">MATPTLPSDLELRKAEAEKRNRAVWKYIAPENDVTPTWSYGQEKLAYYPPAPGTIDTKHRKQSGEFMQFANKALMLGVDLKATSAGGSSGGAKSRTAPGGGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM55</accession>
    <name>C1MM55_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Anion exchanger family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AE_3</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_25768</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anion exchanger (TC 2.A.31.3) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057340.1">
        <property type="nucleotide sequence ID" value="XM_003057294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM55"/>
    <dbReference type="STRING" id="564608.C1MM55"/>
    <dbReference type="GeneID" id="9682779"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25768"/>
    <dbReference type="eggNOG" id="KOG1172">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FWERITI"/>
    <dbReference type="OrthoDB" id="1735926at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005452">
        <property type="term" value="F:solute:inorganic anion antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050801">
        <property type="term" value="P:monoatomic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.570">
        <property type="entry name" value="Helical hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011531">
        <property type="entry name" value="HCO3_transpt-like_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003020">
        <property type="entry name" value="HCO3_transpt_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453">
        <property type="entry name" value="ANION EXCHANGE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453:SF127">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 4 MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00955">
        <property type="entry name" value="HCO3_cotransp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="7">
        <location>
            <begin position="2"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="7">
        <location>
            <begin position="162"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="533" mass="58000" checksum="00E349DD714334AA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MME3</accession>
    <name>C1MME3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56498</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057390.1">
        <property type="nucleotide sequence ID" value="XM_003057344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MME3"/>
    <dbReference type="GeneID" id="9682829"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56498"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="57" mass="6371" checksum="F5AC90BB2596E44C" modified="2009-05-26" version="1">MSKEPSTGKIIHRKQIDYTLLWPIALAPVIPVLGIALRCVSSRTRTRTRPTTAVRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMK3</accession>
    <name>C1MMK3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_38911</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056943.1">
        <property type="nucleotide sequence ID" value="XM_003056897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMK3"/>
    <dbReference type="GeneID" id="9682860"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38911"/>
    <dbReference type="eggNOG" id="ENOG502RVZZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RIVQNKW"/>
    <dbReference type="OrthoDB" id="496967at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="2">
        <location>
            <begin position="216"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="766"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="769"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="782"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="793" mass="84038" checksum="E1049D48DE43682D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP75</accession>
    <name>C1MP75_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_56172</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the adrenodoxin/putidaredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057235.1">
        <property type="nucleotide sequence ID" value="XM_003057189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP75"/>
    <dbReference type="STRING" id="564608.C1MP75"/>
    <dbReference type="GeneID" id="9682212"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56172"/>
    <dbReference type="eggNOG" id="ENOG502RXME">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CGGMGNC"/>
    <dbReference type="OrthoDB" id="5987010at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426:SF65">
        <property type="entry name" value="FERREDOXIN-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="FERREDOXIN/ADRENODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="8">
        <location>
            <begin position="91"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="19"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="163" mass="16780" checksum="FBAA5B2648A11E16" modified="2009-05-26" version="1">MAATLATLPASSSALAARRGGASVTTRRASAHPARATPSSRSRSAALVARASVVRVEFTPSDGGDVIVTDVTKASVLRDVALGDKVQLYEGMAKLLNCGGMGNCGTCKVRVTEGMELLSPRTDAENGKLKGLGEDWRLACQCLVGGDTAPEGAVLKVVNKPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP97</accession>
    <name>C1MP97_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_46672</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057247.1">
        <property type="nucleotide sequence ID" value="XM_003057201.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MP97"/>
    <dbReference type="GeneID" id="9682222"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46672"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0619">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WIRTGHT"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056290">
        <property type="entry name" value="CEPT76/DRC7_peptidase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033551">
        <property type="entry name" value="DRC7/lobo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056292">
        <property type="entry name" value="DRC7_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056291">
        <property type="entry name" value="MORN_DRC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35249">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35249:SF2">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24656">
        <property type="entry name" value="CEPT76_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24671">
        <property type="entry name" value="DRC7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24667">
        <property type="entry name" value="MORN_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="875"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="538"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1053"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="842"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1057"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1088"/>
            <end position="1111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1596" mass="179590" checksum="515D8F2FF2F52676" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPG0</accession>
    <name>C1MPG0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_67030</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057570.1">
        <property type="nucleotide sequence ID" value="XM_003057524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPG0"/>
    <dbReference type="GeneID" id="9683033"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67030"/>
    <dbReference type="OMA" id="CCACACD"/>
    <dbReference type="OrthoDB" id="1045822at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="225" mass="23438" checksum="F4A5CDC32A985050" modified="2009-05-26" version="1">MSNYQPVPTSGAHPDVPGAGYPLAVEWSDGLGGCFADCGVCCMGWWPLGCAQHLFATNVRAEGSEPYSSAFVKALGLTLVFPTLTSAIATTSATAAQAMSPLNTIAHCVFACYGMAHRQEMRRRFNIRGTDCCCDCCACACDGNSEKTDDFCVYLWCAACAICQEARHVRRYSLGIRARRGGGGGMSAGGSGYGPVGGAHGAMDVPVATVIRQGNISPGNTSKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPI4</accession>
    <name>C1MPI4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Photosystem I subunit VI, chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PSAH</name>
        <name evidence="11" type="ORF">MICPUCDRAFT_70928</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Possible role could be the docking of the LHC I antenna complex to the core complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast thylakoid membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the psaH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057963.1">
        <property type="nucleotide sequence ID" value="XM_003057917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPI4"/>
    <dbReference type="STRING" id="564608.C1MPI4"/>
    <dbReference type="GeneID" id="9683058"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70928"/>
    <dbReference type="eggNOG" id="ENOG502RXI9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KWDLYGS"/>
    <dbReference type="OrthoDB" id="496139at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
        <property type="term" value="C:photosystem I reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004928">
        <property type="entry name" value="PSI_PsaH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34787">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT VI-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34787:SF1">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT VI-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03244">
        <property type="entry name" value="PSI_PsaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH57914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="128" mass="13354" checksum="4EBE8A19DCB67987" modified="2009-05-26" version="1">MAFSLAASTSTFAGAKVAVKPVAARRASRATAAKAKYGDESVYFDLGDVESTTGAWDVYGEASTARYPGQQEAFFEKGLGRREAMYSFLALAGPAACLVFGGKGAKDAKLPITVGPQKEAPLGPRDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPR6</accession>
    <name>C1MPR6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57008</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057630.1">
        <property type="nucleotide sequence ID" value="XM_003057584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPR6"/>
    <dbReference type="GeneID" id="9683083"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57008"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="270"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="441" mass="47224" checksum="7945FBB85CFA5069" modified="2009-05-26" version="1">MSASVPSCLPRAIAALRGRVARVRALSSSSPVAAARAALFARPASTLSTTSPTTAPRARRRRVVVRARPSDNEWNVSAAAAAAGGGDGPGRSADTADARAEQLADDAEEAPRKKKLSDLSKFTSAPAAAASPEEKARVDPQLADDSEDEDQDVIAVSFSSADEDPDALLIVDETAEDAAAAAAEEAERGGEAGKPTPPRVGEEGTAAAKEASERRVAANRDRPIVARVLVEYGWKAEPDYQDRSPSAYFRGQTGYSKFYPPEARDYVYARHLMVAVDGTKESERAVEFTVEHLCRSGDLLHLMHVSVDTPPLPTSTTGAPNIIAGLEPQIGTSHHVHTPAPPRSKSESSSSRASSSELEDPRLPSSDPLPKRGESYDWHDSPLRGWSSTPNVWSDVSDADASPAPPEGGLWETRPMYDDTWAPNWLRQSRVRRPLVVARDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ62</accession>
    <name>C1MQ62_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Phosphoribulokinase</fullName>
            <ecNumber evidence="15">2.7.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_49540</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19365"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; Calvin cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the phosphoribulokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.19" evidence="15"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058071.1">
        <property type="nucleotide sequence ID" value="XM_003058025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ62"/>
    <dbReference type="STRING" id="564608.C1MQ62"/>
    <dbReference type="GeneID" id="9683141"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49540"/>
    <dbReference type="eggNOG" id="KOG4203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GLKMRAT"/>
    <dbReference type="OrthoDB" id="738517at2759"/>
    <dbReference type="UniPathway" id="UPA00116"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008974">
        <property type="term" value="F:phosphoribulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019253">
        <property type="term" value="P:reductive pentose-phosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02026">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000619">
        <property type="entry name" value="Phosphoribulokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006082">
        <property type="entry name" value="PRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005655">
        <property type="entry name" value="PRK07429.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00478">
        <property type="entry name" value="PHRIBLKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00567">
        <property type="entry name" value="PHOSPHORIBULOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0113">Calvin cycle</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="16">
        <location>
            <begin position="37"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH58022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="376" mass="42094" checksum="D8165BC7DD13B8D2" modified="2009-05-26" version="1">MATMTMSATCAQPLAARKVRAAKRNVVTRAARDGPVIIGLAADSGCGKSTFMRRMTSLFGGKATPPEGGNPDSNTLISDTTTVLCLDDYHLNDRNGRKESGLTALNLKEQNFDLMYDQVKALKEGKAVEKPIYNHVTGVFDPAEKIESPDILILEGLHPFADERVRDMFDFKIYLDISDDVKFAWKIQRDMAERGHSLESIKASIEARKPDFDEFVDPQKQYSDVIIQVLPTQLIPDDNEGKILRVRMIMKEGVENFDAPYLFDEGSTISWIPCGRKLTCSYPGIKFFYGPDTFFGEEVSVLEMDGQFDKLEELIYVESHLSNTSTKFYGEITQQMLKYQNGPGSNNGTGLFQTLCGLKVRELYERISEKEVVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ83</accession>
    <name>C1MQ83_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_67291</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057712.1">
        <property type="nucleotide sequence ID" value="XM_003057666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ83"/>
    <dbReference type="STRING" id="564608.C1MQ83"/>
    <dbReference type="GeneID" id="9683521"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67291"/>
    <dbReference type="eggNOG" id="ENOG502QUNI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TMDEIAY"/>
    <dbReference type="OrthoDB" id="1923031at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33825">
        <property type="entry name" value="CHITINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33825:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="225" mass="23287" checksum="73909ECCD297279B" modified="2009-05-26" version="1">MQMPRGAHAAAAATALDGGVFVAPAALTFAAGVVACVLGSALSAFLLAFIPTLRALKGAANEIADLAATIREEVPDTLAAVRLSGLELTDCLEEVGELTSEVNSGVKGTGRVLTMGVDTAGTLGKYAAETVRVVVPEVRKRATPLVQKARRAAEVNVERSLEENAQTEEYSGPVVVAAARATKSGVQYARGALRAAGVARQVGRLYKTARDWNQAGVVETQNDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQK0</accession>
    <name>C1MQK0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57319</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058139.1">
        <property type="nucleotide sequence ID" value="XM_003058093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQK0"/>
    <dbReference type="GeneID" id="9683211"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57319"/>
    <dbReference type="OrthoDB" id="564430at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="188" mass="21572" checksum="419507BD57EFBBA0" modified="2009-05-26" version="1">MPVPYTGGVEAQQVRVVVETRRGRPRVRALVAFDVAVARVVSRRAGAEPVRATRPLPFPPRLRRHSFISARVRQADEAKLKKFEDYAENGGGGKEAQELLAEMRDHTEKLAKLRKHEDPRMSFNTPEFKEFSRKFTENFKRNFGKPIEWGMVKKYPWSEPQLQKLDVPVDPDGNPWPLDDAGKPILKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQM4</accession>
    <name>C1MQM4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_49549</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058151.1">
        <property type="nucleotide sequence ID" value="XM_003058105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQM4"/>
    <dbReference type="STRING" id="564608.C1MQM4"/>
    <dbReference type="GeneID" id="9683223"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49549"/>
    <dbReference type="eggNOG" id="KOG0327">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FGCQALV"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17939">
        <property type="entry name" value="DEADc_EIF4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000089">
        <property type="entry name" value="Eukaryotic initiation factor 4A-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="14">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="71"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="252"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH58102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="413" mass="46835" checksum="EAC3436D56031879" modified="2009-05-26" version="1">MSGEGGFNDEAYDSGMQALLAEEKGEDGEMTITDWTEVHESFDAMNLHENLLRGIYAYGFEKPSAIQQRGIVPFTKGLDVIQQAQSGTGKTATFCAGVLQQLDYEKEECQALVLAPTRELAQQIEKVMRALGDYLNVKCHACVGGTSVREDQRILQSGVHVVVGTPGRVYDMLRRRALKPDHIKIFSLDEADEMLSRGFKDQIYDIFQLLPSKLQVGVFSATMPPEALEITRKFMTKPVRILVKRDELTLEGIKQFYVNVDKEDWKLDTLCDLYETLAITQSVIFANTRRKVDWLTDKMRARDFTVSATHGDMDQNTRDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINFDLPTQPENYLHRIGRSGRFGRKGVAINFVTKDDERLLQDVQRFYQTVFEELPSNVADLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQM5</accession>
    <name>C1MQM5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_57345</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057785.1">
        <property type="nucleotide sequence ID" value="XM_003057739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQM5"/>
    <dbReference type="GeneID" id="9683590"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57345"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MEWVLHS"/>
    <dbReference type="OrthoDB" id="5547497at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="77"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="321" mass="34447" checksum="0B8FD45B619E00A2" modified="2009-05-26" version="1">MENAYGKRTTDAFAWTLNISTSVAIVMANKQLMGTAGHGFVFATTLCGLHFACTSGIRFLDGKNENNRADGSAMMVPPREIFLFVVVAIASIVALNFSLMLNTIGFYQVCKLAQIPTMCLLEAIFLGRQFGRKTIQAILIVLVGVGVATVSDMEMNFAGTVAALIGVSCTSAQQIAVSYLQKKHSVSSNFLLAKTSPYMAAAMLGLGPFLDRIVVNEWVTEYEWTEGAVVFLAASCALAVLVNISSFMCIGRFSAVSFQVIGHVKTVLVFFFGFVCFSAPITHRNILGCSLAVMGMIYYSRVQLAEKAQAASRGGALGEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQN8</accession>
    <name>C1MQN8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_16280</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF-assemblin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057791.1">
        <property type="nucleotide sequence ID" value="XM_003057745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQN8"/>
    <dbReference type="STRING" id="564608.C1MQN8"/>
    <dbReference type="GeneID" id="9683597"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16280"/>
    <dbReference type="OMA" id="QNYCDEQ"/>
    <dbReference type="OrthoDB" id="436841at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008374">
        <property type="entry name" value="SF_assemblin/giardin_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412:SF1">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06705">
        <property type="entry name" value="SF-assemblin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01799">
        <property type="entry name" value="SFASSEMBLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="79"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="289" mass="31925" checksum="E539DC1721439983" modified="2009-05-26" version="1">MTARDSRPSALENLAAAENSAPPSPLALTSSAGAVATFRSAEAAAPANRLAHVSERFARFYSDLENEKASRREVETGRRNALYDQVQRLELELENETKRRADADEETRRAIERELKNFERAAETRVQDALAGVKSTLDTLASSLAELHAGLREEREQRRVDVEHLASSVVAKVDECASAVDDERVDRLRREAATLRRVGEDVLRLQEKVDGERSVREAALADVSSAVAELRRAKRGDEDAFHVVALGEIAAAAINAEKEERVAEDESIVRAINEYTRALQDGLRIVNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQN9</accession>
    <name>C1MQN9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cysteine dioxygenase</fullName>
            <ecNumber evidence="2">1.13.11.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_57359</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-cysteine + O2 = 3-sulfino-L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20441"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:61085"/>
            <dbReference type="EC" id="1.13.11.20"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:20442"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.20" evidence="2"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057792.1">
        <property type="nucleotide sequence ID" value="XM_003057746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQN9"/>
    <dbReference type="GeneID" id="9683230"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57359"/>
    <dbReference type="eggNOG" id="KOG4281">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GHAWLVE"/>
    <dbReference type="OrthoDB" id="271433at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017172">
        <property type="term" value="F:cysteine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070483">
        <property type="term" value="P:detection of hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20289">
        <property type="entry name" value="cupin_ADO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012864">
        <property type="entry name" value="PCO/ADO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22966">
        <property type="entry name" value="2-AMINOETHANETHIOL DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22966:SF61">
        <property type="entry name" value="2-AMINOETHANETHIOL DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07847">
        <property type="entry name" value="PCO_ADO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="70"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="324" mass="34386" checksum="82D2F787DBC30480" modified="2009-05-26" version="1">MAREASWSDGPDGARRRTPPDAPHGPVVALYDKCVATLPSVPGVRPVHDDHVRAIMPYLEAVTARDLALEVPDEAKTPPSTSTSRLDRAGLRGGGGGGGGGDGDFFRRGERERVGERERERSSPSSSPEPGARRGLEYLHLHEDLAFTLGVFKFLAAGDAIPTHDHPGMTVMSKILYGAVHVKSYDWVVAPEDEGKPPPPVPVGTPRLARVVRDGVVAAGTTPLALFPTRGGNVHGFTAITPTAMLDVQAPPYALGAGRDCHYFHEVSEGPGGEPAGAGYAWLAAAPSQPESFRIDHGTYRGPKFGSNATEGGYYTYEGGHMMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQP0</accession>
    <name>C1MQP0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_16010</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057793.1">
        <property type="nucleotide sequence ID" value="XM_003057747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQP0"/>
    <dbReference type="STRING" id="564608.C1MQP0"/>
    <dbReference type="GeneID" id="9683231"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16010"/>
    <dbReference type="eggNOG" id="KOG0062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANDVAPC"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="56"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="290"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH57744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="560" mass="60409" checksum="79E3DE22DA61F379" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR26</accession>
    <name>C1MR26_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_26511</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057856.1">
        <property type="nucleotide sequence ID" value="XM_003057810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR26"/>
    <dbReference type="STRING" id="564608.C1MR26"/>
    <dbReference type="GeneID" id="9683670"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26511"/>
    <dbReference type="eggNOG" id="KOG4028">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DVAYWCH"/>
    <dbReference type="OrthoDB" id="184109at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010796">
        <property type="entry name" value="C2_B9-type_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968">
        <property type="entry name" value="B9 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968:SF6">
        <property type="entry name" value="B9 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07162">
        <property type="entry name" value="B9-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51381">
        <property type="entry name" value="C2_B9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="176" mass="19393" checksum="94532578B41572BD" modified="2009-05-26" version="1">MAELHVVGEIVGAHGFEDRNLFCKWGVEAGSMWDLVEGEAGGQTQCDYPPDGEPGVVWAHPVDLHYATKSLIGWPKMWFQVWCLDVHGAKDLAGYGFCHVPTSPGMHEVEVATWVPEGSGIEKLTAFFVGGRPRLKFEEVIHSPGDRFRLQTRAAGVIKLQLGVCVRDFAKYAVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR35</accession>
    <name>C1MR35_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57510</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057861.1">
        <property type="nucleotide sequence ID" value="XM_003057815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR35"/>
    <dbReference type="STRING" id="564608.C1MR35"/>
    <dbReference type="GeneID" id="9683299"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57510"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PWHETTC"/>
    <dbReference type="OrthoDB" id="498371at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="434" mass="46920" checksum="9F932DE4470FE4BE" modified="2009-05-26" version="1">MNRGGVDDNTGDGSTSANLDNDAPPLLERFAAVARDVLYVHILPRLDSGDLAVLATVNRKMRDVVFESPVEHDVRDVAAVRRELARVPNFVGSIGRLTWAKDQRGCPWDARTFTCIARGGNVEVARWAKERGCPWNGGTCAFAAEGGHLEMLQWLRANGAPWEESTCAFAAGGGHLEVLQWARANGAPWNERTCANAAKGGHLEVLQWARANGAPWYEWTCTYAARGGHLEVLQWARANGCPWHETTCAWAACGGHLEVLQWARANGCPWHETTCAWAACGGHLEVLQWARANGCPWDSFTCTGAAKGGHVEVLQWAVANGCPWDSWQTCANAAKGGHLEVLQWARANGAPWDNEGTCANAAKGGHLEVLQWARANGAPWHETTCTYAAIYGHLEVLQWARANGAPLHNGGICVHAASGGHLEVLQWARANGVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR59</accession>
    <name>C1MR59_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_33176</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058247.1">
        <property type="nucleotide sequence ID" value="XM_003058201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR59"/>
    <dbReference type="STRING" id="564608.C1MR59"/>
    <dbReference type="GeneID" id="9683312"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33176"/>
    <dbReference type="eggNOG" id="KOG2381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CENSAEY"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044571">
        <property type="entry name" value="P4KG1-8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45800">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45800:SF4">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE GAMMA 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="234"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="323"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="500"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="411"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="422"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="540"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="831" mass="89098" checksum="9CEB65FE47E40518" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR70</accession>
    <name>C1MR70_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57548</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057880.1">
        <property type="nucleotide sequence ID" value="XM_003057834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR70"/>
    <dbReference type="GeneID" id="9683318"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57548"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912052" evidence="2">
        <location>
            <begin position="28"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="145" mass="14428" checksum="FEE1A44E6FDD3055" modified="2009-05-26" version="1">MKEWYKWWFCVAAVLAVLAHCASPVAATYYGTYCVEPAVWYDVDGVCVYPGTPQYTVVVNRPGYVGAGAVGFAAGKASNYRPNYGRPDRPGGPGGDRPGRGSGGPSTRPSAGRGGGSVGGGGRGGGGRGGGGRGGGGRGGGGRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRG7</accession>
    <name>C1MRG7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vacuolar iron transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_57647</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Fe(2+)(in) = Fe(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:28486"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:28487"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057924.1">
        <property type="nucleotide sequence ID" value="XM_003057878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRG7"/>
    <dbReference type="STRING" id="564608.C1MRG7"/>
    <dbReference type="GeneID" id="9683743"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57647"/>
    <dbReference type="eggNOG" id="KOG4473">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PWKGEYA"/>
    <dbReference type="OrthoDB" id="73465at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02434">
        <property type="entry name" value="Nodulin-21_like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="FE(2+)/MN(2+) TRANSPORTER PCL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH57875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="279" mass="29321" checksum="DAD3F77E2BBCD6B4" modified="2009-05-26" version="1">MASASEVRQRGSGPGRDLNAARVAYDALDVDLSRVAHDAKKAHGSAEAHAGASGKYVKSLVFGGLDGIITTFAVVAASVGGSLGSDVILLMGFANLVADGLSMGFGDYLSSKAEFEYTRAEHKREKWELDNYPEGEKREMVELYVARGMTEADAENVIDVMAKYPNFFLDVMMVEELGLMPPDDGESPAKNGLVTFLAFVCFGFVPLTSYVLAGVTGASADANFIAACVLTALMMLALGAAKAKFTNQSTTRSAALMLLNGSIAATAAYLVSWGISSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRY8</accession>
    <name>C1MRY8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58280</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058958.1">
        <property type="nucleotide sequence ID" value="XM_003058912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRY8"/>
    <dbReference type="GeneID" id="9684029"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58280"/>
    <dbReference type="eggNOG" id="ENOG502S875">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WEGCFLT"/>
    <dbReference type="OrthoDB" id="511368at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703:SF2">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="357" mass="38464" checksum="307A0EE8F891BB14" modified="2009-05-26" version="1">MAHSEDVVVVANGAVLAGLALASPADFIRESAPRGAYTAGRAEFGKGMGWWSAHLARLRRSLRAMRERDPGCFELGSEIPADDDTLATWVAPSVKLALDAIDAKTLANAKPCDAVKPPKQAKQHCVVIIVAPAPSGYDVFVHASPLQIRVDEFYRGVDVAVLGPPRRNPAAKDTNWVRDRRQLEARKREAAADEVILADDDGEVLLEGLVTNLFVVVETEDPGGGHLPRRHAAFTAPTTRCLPGLARQAVLDALDAEGIPWEERAPTASERSEWSEAFVTNAVKLARPVRTLRWPRGIPGKLEVEFGPCAGSGEKPRGDSEWKSEVKCELDASPGPVCQAVLRRLNASMASDVGPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-05-03" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS05</accession>
    <name>C1MS05_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_39909</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058966.1">
        <property type="nucleotide sequence ID" value="XM_003058920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS05"/>
    <dbReference type="GeneID" id="9684038"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39909"/>
    <dbReference type="OMA" id="NHEYGRY"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910628" evidence="1">
        <location>
            <begin position="25"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="209" mass="21999" checksum="2C2B624FFF276073" modified="2009-05-26" version="1">MARLSSIALVALVFAFAFAGAANAQGVPRPTTEAASGRGFRDSYYKEPIKEPYYKEPIHHACVGVEIAKDGETYSPCGKFDKCCDGFFCRVDAPLFAKLPYKEITGPVDSLAQATSNLNQCCIPEDALDVTELVCPAEFFDSTAGTCSLNAANNAGYTWAGTGGSALNELACLCCDGVIRRDGYRNNAKITCNVPGTGNAGGTCPQPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS54</accession>
    <name>C1MS54_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_39937</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058987.1">
        <property type="nucleotide sequence ID" value="XM_003058941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS54"/>
    <dbReference type="GeneID" id="9684426"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39937"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="53"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="212" mass="22272" checksum="C03F61F5EA6BC3EA" modified="2009-05-26" version="1">MSRLRAATRTIDAGSGSSAFNPFAAVARLLARLARAVFETLVTLVLRRILGERETFDCPLVTVSDVIDAHGLSDVGLLKVDVERAELDVLRGVREEHWPLVRQVAMEVHDGGGEGVASTSSASLASSAAGASASSASKKTQTGKRRTTVADAAAPSTAGRLEEVTSLLVNAGGFDPRRIFVEQHAGLEGSTLWNVYATRAEGYDVASSYDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSK9</accession>
    <name>C1MSK9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="8">5.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_39596</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.-" evidence="8"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058341.1">
        <property type="nucleotide sequence ID" value="XM_003058295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSK9"/>
    <dbReference type="STRING" id="564608.C1MSK9"/>
    <dbReference type="GeneID" id="9684137"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39596"/>
    <dbReference type="eggNOG" id="KOG1371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAPVNPY"/>
    <dbReference type="OrthoDB" id="9402762at2759"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007956">
        <property type="entry name" value="PRK10675.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF47">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="9">
        <location>
            <begin position="10"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="357" mass="38462" checksum="5AA35203E34A8046" modified="2009-05-26" version="1">MAALERATVLVTGGAGYIGSHTVTQLLTAGCVVHVVDNLDNSSEESLRRVRELVGEEKAAKLTFHECDILDAVKMDKAFAAAGKVDAVIHFAGLKAVGESVAKPMRYYRNNIVGTMALVDVMERHGCRKIIFSSSATVYGEPATVPCTEEFPTAALNPYGRTKLFVEHILTDMQAASPEWKVILLRYFNPVGAHPSGRIGEDPKGIPNNLMPFIQQVAVGRRPVLSVFGDDYKTADGTGRRDYIHVMDVADGHAAALTKIVDDASMPDGCVTVNLGTGKSTSVLELVAAFAKASGKEIPTKIVARRPGDAAEVYAQTEKAKEVFGWEAKLDIERCCVDQWKWASANPYGYGTEADAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSQ7</accession>
    <name>C1MSQ7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_2158</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058367.1">
        <property type="nucleotide sequence ID" value="XM_003058321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSQ7"/>
    <dbReference type="STRING" id="564608.C1MSQ7"/>
    <dbReference type="GeneID" id="9684159"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2158"/>
    <dbReference type="eggNOG" id="KOG0339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MRRTIEP"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="93"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="316"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="494" mass="51668" checksum="7ADE67423F37D27F" modified="2009-05-26" version="1" fragment="single">RRTIEPLGRVDHAAAAYAPFQKKFHPRDNPDVAAWSERDVEARRRALDVQIVGRDPPRMIERFGQCGGVDAVTLRTLKQRGYESPTPIQACALPALLRGRDVLGIAKTGSGKTAAFLIPATHHCLAQPEIAKGDGPIVLTLAPVRELAAQIVSEARRFGKPHGVRVVGVFGGASKQDQFKDLRAGGEIAIGTPGRVVDLCKTKNGLSLTRVTFLVLDEADRMLDLGFEASVRSICDAIRPDRQAAMFSATMPPRVRGLVRDVLTGNGEGEEGGGGGGGGGGGGWLTITVGRPGGANADVAQTVDVVAPGEASRVAWLRERIHAFVDEGQVIVFASRKQAVDDVVATLREAGVRAEGVHGDMDQARPCLHWALSAFKKGDAHALVATDVAARGLDIPSVRTVVSLHPPRDVESHVHRIGRTGRAGDTDGRAFTLVDASTPGKFLSDLVQNLRGAAQHVSGALLKLTARRGGGKGGGGGGGGGGARSKVGGLGIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT78</accession>
    <name>C1MT78_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_57965</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058439.1">
        <property type="nucleotide sequence ID" value="XM_003058393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT78"/>
    <dbReference type="GeneID" id="9683877"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57965"/>
    <dbReference type="OMA" id="QRWISAW"/>
    <dbReference type="OrthoDB" id="10639245at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="437"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="160"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="472" mass="49052" checksum="6B159224E4EB90CA" modified="2009-05-26" version="1">MRLAHARPRLAATATASTSTSEPATAGVRASSSLAARRRRVSVVVALRRRTPSRARVVRPLAALPEEISGLARRPGHVQRADAPANALRGDATANARLVSSNPSNPVVSNLAAARAAAPAPPPTPNAVTVTLPASAIFALTLGSVAACGTVFMLAVAPALRAMERASVAAERAAEASEKAMLEFEKLSAQTAEDLPKTLAEMEAAGQEWDELGEELRELLARVERWGQFSGAEEALTKLTTSVLEEPTRVIDEAESYIKRLSDDFTRTLNQLSDWDKDLRSSVERAAFSEAWERQGNGEKKLLSSDADGGKGGGGREDGGKASPLLLLARQRQAVADAIAVAEAATADAQAATAELMSGGGVDADGDAIAAMEGKAESVTTALREALLAVEEAKEASRSFDDGDGDGDGDGDAARSSGLLALERELERKRDAAVERALKGSVDADGDADGDAADAEEGDRGPNDSGDNAFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTE0</accession>
    <name>C1MTE0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58036</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058472.1">
        <property type="nucleotide sequence ID" value="XM_003058426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTE0"/>
    <dbReference type="STRING" id="564608.C1MTE0"/>
    <dbReference type="GeneID" id="9683911"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58036"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="676"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="184"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="324"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="684"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="707"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="745"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="760"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="788"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="818"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="840"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="887" mass="94995" checksum="6577FEFBAC1C9D1D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTU1</accession>
    <name>C1MTU1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58550</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059080.1">
        <property type="nucleotide sequence ID" value="XM_003059034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTU1"/>
    <dbReference type="GeneID" id="9684820"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58550"/>
    <dbReference type="eggNOG" id="ENOG502S4AS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VAYVTVW"/>
    <dbReference type="OrthoDB" id="503863at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36059">
        <property type="entry name" value="OS02G0175800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36059:SF2">
        <property type="entry name" value="OS02G0175800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="85" mass="9689" checksum="EA7750D52286AD6F" modified="2009-05-26" version="1">MAAQFIRQLGALKVKEVPDFLARKLSAENVTRNATTFMEEYRVRYINTGSPAPIFHVLGGVFTMAYITCWPAEYRHMIAAREGKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTY6</accession>
    <name>C1MTY6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_8703</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059100.1">
        <property type="nucleotide sequence ID" value="XM_003059054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTY6"/>
    <dbReference type="STRING" id="564608.C1MTY6"/>
    <dbReference type="GeneID" id="9684845"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8703"/>
    <dbReference type="eggNOG" id="KOG3267">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10255963at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047_YjbQ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615:SF16">
        <property type="entry name" value="SECONDARY THIAMINE-PHOSPHATE SYNTHASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YJBQ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004681">
        <property type="entry name" value="UCP004681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01314">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="137" mass="14965" checksum="B44EBF3BC64E6E4A" modified="2009-05-26" version="1" fragment="single">LEYATLRGIQLIDVTADVRARVKAAGIENGVVNVLSRHTTTAVTINEAEGRLMDDVRQYLTRLAPPGDPYLHNDLHLRRVPVVEPENAHSHLLSMLIGNSETIPVVDGELALGTWQSVMLVELDGPRTRTLGVQVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU08</accession>
    <name>C1MU08_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_17567</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059413.1">
        <property type="nucleotide sequence ID" value="XM_003059367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU08"/>
    <dbReference type="STRING" id="564608.C1MU08"/>
    <dbReference type="GeneID" id="9684573"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17567"/>
    <dbReference type="eggNOG" id="KOG2355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GGKHMVP"/>
    <dbReference type="OrthoDB" id="6512918at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00267">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158:SF12">
        <property type="entry name" value="ABC TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158">
        <property type="entry name" value="SKFA PEPTIDE EXPORT ATP-BINDING PROTEIN SKFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="68"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="379" mass="40534" checksum="9615CBD1182DF1E9" modified="2009-05-26" version="1">METAGPFAALAAQQKRAKTTEDDDASAAAECDVSIAPAVANAAAKPSSPLPSASPASTAPGAAPRWGVAVNDLDWSYPGIDGQPVAGQPPLIKNFNLKLAPGSCCLLLGANGAGKTTLLKILGGKHMVPKEKVLIHGREAFYDTGLTTSGQLSYIGGDWQRDVAFAGYGVTLAGDFPASKMLNSIPGVDEARRKKIIEVLDIDPTWRMHQVSDGQRRRVQLAYGLMIPYSVLLLDEITVDLDVLGRADLMAFLRQECMERSVTIVYATHIFDGLEQFASHVAFVAGGELRFCEPIEKIDGLRDLEPGALLSTVEGWLRKEAEIKREALAKKGIVPKKVFEYVRNSGWGSGRTASTVSFGPELGMKHEGIKGSSNAVMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU17</accession>
    <name>C1MU17_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_17833</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MnmG family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059418.1">
        <property type="nucleotide sequence ID" value="XM_003059372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU17"/>
    <dbReference type="STRING" id="564608.C1MU17"/>
    <dbReference type="GeneID" id="9684569"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17833"/>
    <dbReference type="eggNOG" id="KOG2311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RFPGRTH"/>
    <dbReference type="OrthoDB" id="3329at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070899">
        <property type="term" value="P:mitochondrial tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.570:FF:000001">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000002">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="entry name" value="GidA associated domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047001">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00136">
        <property type="entry name" value="mnmG_gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="GLUCOSE INHIBITED DIVISION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PROTEIN MTO1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="SAM_GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM01228">
        <property type="entry name" value="GIDA_assoc_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain" evidence="6">
        <location>
            <begin position="564"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="640"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="663" mass="69232" checksum="A562756CE25DC160" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUD9</accession>
    <name>C1MUD9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58768</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059177.1">
        <property type="nucleotide sequence ID" value="XM_003059131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUD9"/>
    <dbReference type="GeneID" id="9684921"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58768"/>
    <dbReference type="OMA" id="MAKAKCV"/>
    <dbReference type="OrthoDB" id="439983at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="85" mass="9073" checksum="1679CA65FFE49B5E" modified="2009-05-26" version="1">MSAATAFLTTPVRASAVAKRATTKRAVAALAAAKETTPVVKAEDFKCPLTCEEKSNDATTHEMAKAKCVHPERPVSKACQDCPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUM3</accession>
    <name>C1MUM3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_27286</name>
        <name evidence="11" type="ORF">MICPUCDRAFT_48264</name>
        <name evidence="12" type="ORF">MICPUCDRAFT_48289</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059221.1">
        <property type="nucleotide sequence ID" value="XM_003059175.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061708.1">
        <property type="nucleotide sequence ID" value="XM_003061662.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061754.1">
        <property type="nucleotide sequence ID" value="XM_003061708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUM3"/>
    <dbReference type="STRING" id="564608.C1MUM3"/>
    <dbReference type="GeneID" id="9684961"/>
    <dbReference type="GeneID" id="9686907"/>
    <dbReference type="GeneID" id="9686953"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27286"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48264"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48289"/>
    <dbReference type="eggNOG" id="KOG1745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANDCAIH"/>
    <dbReference type="OrthoDB" id="494251at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000078">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000044">
        <property type="entry name" value="Histone H3.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="10">
        <location>
            <begin position="44"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH54338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH54384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH56353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="136" mass="15356" checksum="0709922BE2E9E3C6" modified="2009-05-26" version="1">MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAILALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUR1</accession>
    <name>C1MUR1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_40266</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059542.1">
        <property type="nucleotide sequence ID" value="XM_003059496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUR1"/>
    <dbReference type="STRING" id="564608.C1MUR1"/>
    <dbReference type="GeneID" id="9684982"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40266"/>
    <dbReference type="eggNOG" id="KOG2445">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EWECTAR"/>
    <dbReference type="OrthoDB" id="364224at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF3">
        <property type="entry name" value="NUCLEOPORIN SEH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="328"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="296"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="377" mass="37870" checksum="EE6C2C5EF5F2BE6E" modified="2009-05-26" version="1">MDAEDETAVANDDAVQVHGTALETRGEVTDTAYDTSGTRMATCTSTGAIHVFDREGGEDGSPGVWRQSAGWLAHDRGASATSITFAGAEFGRCVASAASDGTVCVWREVLRAPGADAAAAALAAAEDGAAPWERCGFLRANASAVTAIAFAPAAFGLQVACGGDDGVVRFYSPADTLALAGWELCNEHEALTPGARVTALAWCRPAGADGGGGDRTGGAPMLAVALSWPGSGTNDARVLTYDDANMRWRITSTLYAGGATVSALAWAPRTNVADAAETIAAALGRDAGVFRVHGGDGAGGGGDASARAAPPGGGVGEGGDRRSELAASLSHPAAVASMDWNAVGNTLATSAMDGVVRMWAANAQTGAWEARAQLVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUW7</accession>
    <name>C1MUW7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_58959</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059573.1">
        <property type="nucleotide sequence ID" value="XM_003059527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUW7"/>
    <dbReference type="STRING" id="564608.C1MUW7"/>
    <dbReference type="GeneID" id="9685013"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58959"/>
    <dbReference type="eggNOG" id="KOG0032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HDRSITH"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0140">cGMP</keyword>
    <keyword evidence="6" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="73"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="359"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="525"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="562" mass="61901" checksum="8B031BFA8EE02664" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUX9</accession>
    <name>C1MUX9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Set domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58974</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059578.1">
        <property type="nucleotide sequence ID" value="XM_003059532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUX9"/>
    <dbReference type="STRING" id="564608.C1MUX9"/>
    <dbReference type="GeneID" id="9684710"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58974"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FHAWERS"/>
    <dbReference type="OrthoDB" id="514820at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF298">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE ATXR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="41"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="394" mass="40554" checksum="19129B848AE4FF0B" modified="2009-05-26" version="1">MAAARRGACVSIARARRLFFSCAVARSTERAASEDDARGSPSFAIPDGAPFFLGKTDASGRGLFASRAIARGELILRAPPLVAHPALDAIADVCYACLRRIPSATAQTRDDGSGPKKPAPVAAEVPDGARFCGERCATDASARFHAWERSVGDALAPLRRRCEDHGGLKFPLLAARLAFAVLSSSVAARDADALCRVNFPPGVAPEDWLEEHAMLKVALSRGLAIRRLADARGGGTGGGGGGGGGDAQLAAAASDREREARVVDGALTPEWYVGVVGRMHLNAFRVEIPAIVDGGRGGGGAGAGGCGHEHGGERGGERGGERVSSSSAFRDAMEAALSSVASGRGTGSALYGLPSMLNHSCDPSVDAAWTYGDATLVLTARRDVAAGEELRISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVA1</accession>
    <name>C1MVA1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59114</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059338.1">
        <property type="nucleotide sequence ID" value="XM_003059292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVA1"/>
    <dbReference type="GeneID" id="9684778"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59114"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="86" mass="8896" checksum="C0A02F458D6C36D7" modified="2009-05-26" version="1">MDNYPQTWTGGVFTCVAHACVRNPEPRAMNDVGGDGGEGGGGGGVVGGFTDFVAESGRSLGGAFGKIGELMPTRWSREMDKMGINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVT3</accession>
    <name>C1MVT3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxisomal ATPase PEX6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Peroxin-6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_18687</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059803.1">
        <property type="nucleotide sequence ID" value="XM_003059757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVT3"/>
    <dbReference type="STRING" id="564608.C1MVT3"/>
    <dbReference type="GeneID" id="9685535"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18687"/>
    <dbReference type="eggNOG" id="KOG0736">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PRDHINF"/>
    <dbReference type="OrthoDB" id="498881at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000109">
        <property type="entry name" value="Peroxisomal biogenesis factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF9">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="42"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH55755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="339" mass="35059" checksum="1D4D1008939AD4D6" modified="2009-05-26" version="1" fragment="single">VPTTSWSDVGGLEDVKAAIREIVELPLKRKALVRRVTGGVGGRSGALLYGPPGTGKTLLAKAVATECAFLSVKGPELVNMYVGESERNVREVFERARDAAPCVVFFDELDALAPARGAGADSGGVMDRVVSQARSVLDGANAAAARDDDAGGLLFVVGATNRPDLVDSALLRPGRFDRLLYVGVDASVDGRARVLTALTRKFTFEEEEWGRASGGGGGGGGGAGAGSGRSRVVEKLARMIPARFTGADVYALCADAWTRAAKRAIAVGEASGGGGGEEEDEEEDGSDARGDGGAVVVVVRGSDFVDALGELTPSLTDEDVAHYARMREGFEGGRSGRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVU5</accession>
    <name>C1MVU5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA:m(4)X modification enzyme TRM13</fullName>
            <ecNumber evidence="1">2.1.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_5259</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(4) in tRNA(His) + S-adenosyl-L-methionine = 2'-O-methyladenosine(4) in tRNA(His) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43196"/>
            <dbReference type="Rhea" id="RHEA-COMP:10401"/>
            <dbReference type="Rhea" id="RHEA-COMP:10402"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74477"/>
            <dbReference type="EC" id="2.1.1.225"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(4) in tRNA(Gly)(GCC) + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA(Gly)(GCC) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43192"/>
            <dbReference type="Rhea" id="RHEA-COMP:10399"/>
            <dbReference type="Rhea" id="RHEA-COMP:10400"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.225"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(4) in tRNA(Pro) + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA(Pro) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32767"/>
            <dbReference type="Rhea" id="RHEA-COMP:10397"/>
            <dbReference type="Rhea" id="RHEA-COMP:10398"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.225"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase TRM13 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.225" evidence="1"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060100.1">
        <property type="nucleotide sequence ID" value="XM_003060054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVU5"/>
    <dbReference type="STRING" id="564608.C1MVU5"/>
    <dbReference type="GeneID" id="9685251"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5259"/>
    <dbReference type="eggNOG" id="KOG2811">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="258806at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106050">
        <property type="term" value="F:tRNA 2'-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007871">
        <property type="entry name" value="Methyltransferase_TRM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039044">
        <property type="entry name" value="Trm13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12998">
        <property type="entry name" value="TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12998:SF0">
        <property type="entry name" value="TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05206">
        <property type="entry name" value="TRM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Methyltransferase TRM13" evidence="3">
        <location>
            <begin position="9"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="248" mass="25638" checksum="2DC2B79426870E17" modified="2009-05-26" version="1" fragment="single">PFNARHATQQAAIVSLMASAGLVEETRPRGPGTEAAAAAAAAVARPPVYVELGAGRGYLSHFLCEAYGPRDVVLVERRTYRNKAERSIRREPTTAENPGSDPAAAVVCERLKVDIKDLDVAGVGVVDGRDVVFTGKHLCGGATDLALRSVFGRRSTSDGSGDGDGDGDGDGDGDGDGDGDGDGSGSGDGGGFGGTKITFTTKGVAIATCCHHRCDWRAYVNKAFVKRLGFKSAEFALLAKMSSWATDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW03</accession>
    <name>C1MW03_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65518</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060128.1">
        <property type="nucleotide sequence ID" value="XM_003060082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW03"/>
    <dbReference type="GeneID" id="9685566"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65518"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="162" mass="18372" checksum="64BBD16122B2C863" modified="2009-05-26" version="1">MCASGTRPTMRCRIDAVARALAARRRAAYRGRGGRSRGRARGEGSARRDDGSRERARAARERRFRAVPSRRAPRCDLRGPPRIGRGRTRRIAFVGRCVFLVIKYGVLSRFAKIQKTLPPPLVLSRERAASFPRRARDRSIDRSITRRPSLRTALESRPPPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW15</accession>
    <name>C1MW15_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_59589</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060135.1">
        <property type="nucleotide sequence ID" value="XM_003060089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW15"/>
    <dbReference type="STRING" id="564608.C1MW15"/>
    <dbReference type="GeneID" id="9685286"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59589"/>
    <dbReference type="OMA" id="CPITKVM"/>
    <dbReference type="OrthoDB" id="629492at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052085">
        <property type="entry name" value="WD-SAM-U-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573:SF1">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="3">
        <location>
            <begin position="75"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="500" mass="53425" checksum="868DDBE0AF093210" modified="2009-05-26" version="1">MSIFDALRRDADLRRRRGARDGDGDGDVDAVGDAVVEREEGSDAAGAPPPFDARDASNASAAAAAAAAAAADDDDEPEALCCPITKVMLRDPVFLAGSGNTYERDAIERFWRGSGGSRGRKRDPLTNARVANASLFTNWDKRREVQAWLSRNEGKVPEGWASRDDVPPAKETTDDARRRSKNGGGGGGGARRWATIAVAFVVSSIVIVAFQAGAVERAWRRGWEWRRSIGWRAPHSGGGGGGGDDGDSGLFFGGSTNREMKTRLRWESALIERFGEDRFKTMAPIAPPHGSRIRAMSGPHGELAILIPPGGVFNAGAVAETAFTGAWTAITAAWTYGAMIGPSPLFALFSVPFWGVGAHLGKTVAAAMFESTRVDFVPPAAAPAAPPPGDVHRRGLRPPPAREELGRFHYSREAFGRELARADGPLGAISGLNVVTRTHVNDVPTTTLNLFVGVETYEMGVGVSEVEQRWMRATALEALARARVFLPRGGGRREFVSRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWB1</accession>
    <name>C1MWB1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59697</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059893.1">
        <property type="nucleotide sequence ID" value="XM_003059847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWB1"/>
    <dbReference type="GeneID" id="9685623"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59697"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="203" mass="22228" checksum="4C8A66C2A995F201" modified="2009-05-26" version="1">MSGRPARIRVSKAKVKAARCDALAEYRTELDFRKQKRGQRKCFFRVEKLSFTDGRTELGLESRLRLSLQLPEEPDRQGRAEIVRWAPGIPLAATRRRARGGGMSATARSAALLGLLGLGVGVNVYGAYYVLALNGQAPATFVVGGASAIGDGRDLWAQTAAAAAAEERSAAEKKKKEEGENGRRWWKPWRGRSRVTSGEDVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWI5</accession>
    <name>C1MWI5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_18468</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060222.1">
        <property type="nucleotide sequence ID" value="XM_003060176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWI5"/>
    <dbReference type="STRING" id="564608.C1MWI5"/>
    <dbReference type="GeneID" id="9685369"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18468"/>
    <dbReference type="eggNOG" id="KOG0167">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2016400at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16655">
        <property type="entry name" value="RING-Ubox_WDSUB1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052085">
        <property type="entry name" value="WD-SAM-U-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573:SF1">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U-box" evidence="1">
        <location>
            <begin position="25"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="99" mass="11193" checksum="C507CD6F5D7FD589" modified="2009-05-26" version="1" fragment="single">MGIPQLGFVTGLLYAVRRAGRARADPPDSLRCPITQELFRDPVVVTQTGYTYDRDAIERWLRQKTPPTDPSSNVELYATDIVPNWALRDATNEWCARNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWQ8</accession>
    <name>C1MWQ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_65271</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059670.1">
        <property type="nucleotide sequence ID" value="XM_003059624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWQ8"/>
    <dbReference type="STRING" id="564608.C1MWQ8"/>
    <dbReference type="GeneID" id="9685407"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65271"/>
    <dbReference type="eggNOG" id="KOG0975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EWTIDND"/>
    <dbReference type="OrthoDB" id="25921at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050571">
        <property type="entry name" value="Class-IV_PLP-Dep_Aminotrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42743">
        <property type="entry name" value="AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42743:SF22">
        <property type="entry name" value="D-AMINO-ACID TRANSAMINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="438" mass="46629" checksum="D80829A28F3E63E4" modified="2009-05-26" version="1">MSAPARCPLAATATGRKLERAAAAAAAAARARGRRRRRRAHPPRPRWTTAVAAASSPSPSPPSDDDDDDIPVLDAAGVHARLASRTHDAAKDTFAAFYSSWTGCITTDPAAIVLPFDDHMVHRGHGVFDTAHLENGALHLLDRHLARFKRSMAAARVPPPFGDGDGDGDDCAEKMKAIILRVAAASGVRDHGQVRYYASAGPGGFALSREECVRSVFYVVVVRKKRRAGAGEKPKRLRVVTTPIPMKPGVFATTKTTNYLPNALVVADAIDKRADVGLWVTENGFVGEGPSMNVAFLVPADDAGGGGGGDEEDETVCGEAFKTNKKWKLVSPPTSNILAGCTVARVAELVNDAKVLEHLNVAAFEFRDVGVEEGKRARETMLIGSVIHVAPVVEWDGEAVGDETTTETPIADALHAAVVRDIATNVPELTPVPYELYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX08</accession>
    <name>C1MX08_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59320</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060014.1">
        <property type="nucleotide sequence ID" value="XM_003059968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX08"/>
    <dbReference type="STRING" id="564608.C1MX08"/>
    <dbReference type="GeneID" id="9685102"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59320"/>
    <dbReference type="eggNOG" id="KOG3017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VGANQIF"/>
    <dbReference type="OrthoDB" id="2015857at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37231">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37231:SF2">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="184" mass="18875" checksum="A88BD535DD9B9B9B" modified="2009-05-26" version="1">MSSALLAARVVPPRALRIARVASRPTRARRVATHPVVAGLKDLDKDLAKVSPSRTRDALAGDDRELRRQAIVGVGGCVSCAIMGYSLYTLRHTGCGLPPGPGGLVGAAEGLSYLYVCALVAYSAVKKVRTGSGLPEGPGGVLGLAEGLAYLLALGGVYCLLGQVEDFGFIPNAVPVEGGPCFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXB0</accession>
    <name>C1MXB0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60090</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060661.1">
        <property type="nucleotide sequence ID" value="XM_003060615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXB0"/>
    <dbReference type="GeneID" id="9685803"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60090"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="296" mass="31569" checksum="5696D4508F93FC21" modified="2009-05-26" version="1">MAVDAEGGPPPAGEDDGAGELYWRSRANAKDAELRLLRALVGASSRVRFEAKSPSSEARPSEDASTSPRPPPPPPPPPPPSVANTPLSSPLVASPLATARRAREEEDAATAIASARAIEHLQTELLRREAQARRTAAALARAKEDGETRDARVAALCERWERAAAETRAAHEDEVGALRMENDELKLRVDEADARAATAEAELSRATAARDTALAELALERRLAEADAERERRRRREAPVTPPRLVFTPPPPPPGPRFGGTAGDAKTPPPVPREAQLAAVLGGGREPLFIPAVDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXK0</accession>
    <name>C1MXK0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-methionine-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_34655</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060410.1">
        <property type="nucleotide sequence ID" value="XM_003060364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXK0"/>
    <dbReference type="STRING" id="564608.C1MXK0"/>
    <dbReference type="GeneID" id="9686143"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34655"/>
    <dbReference type="eggNOG" id="KOG1635">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TEKMFWR"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050162">
        <property type="entry name" value="MsrA_MetSO_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42799">
        <property type="entry name" value="MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42799:SF2">
        <property type="entry name" value="MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="8">
        <location>
            <begin position="49"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="258" mass="28115" checksum="67A5031A2F65AB71" modified="2009-05-26" version="1">MLNGGGAKSALIDEKDALPGRKEEMKVTNKHYVLGNPIKEPFPDNLETCVFATGCFWGTEKMFWRVPGVYSTSVGYCSGHTQNPTYEEVCSGRTAHTEAVQVAWDPKIVSFADLLAMHWTCHDPTQGMRQGNDSGTQYRSGIYCSTAKQLEVAKDSAKAYAAALEAAGRSGKITSDLIGPEGNTVYYFAEDYHQQYLAKPNARPYCSAQPTGVPVPETWLKANGAKLSAGYWAKYGPRPGCTIQVANEPVPLEEAMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXM6</accession>
    <name>C1MXM6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60216</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060424.1">
        <property type="nucleotide sequence ID" value="XM_003060378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXM6"/>
    <dbReference type="GeneID" id="9685862"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60216"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="456" mass="47633" checksum="211D1B61E44CE0D0" modified="2009-05-26" version="1">MVAKNPKKRKTAATTPTKDDAKSPRGGRGKSRVVAATATIRKKTPRAKSPSAAGRARARVGKSASAKSPAAKLPTSPAAGRGRKHTPRKPRAARAALSPPSQNAKKKTTRARKLAEAKKAPKKSPKKARPPSSKKPTKEAARVVRAGGVAKSPKKKKRRPSSAKKVKPRPKKRPASASKAPPSDASASSRKSDEKKAADKTKKTKAALAVRAGRVAKSPASKQKKQQQQQRRQPKMKQHAKPKPKPKPARLRPPPAPANSTQMIMHQYNAGLAKSGGAKKTVRVRGGRIDTFGSLLPARARATTTATRPPVAPKKGGAATATATATATARTKAKAKARTKAKKRAPPPSSSSRGMMFSPTPSAGTGGDYAIPERAGAFGASRLPSDVFTPGGGARAARDDDEVSNASTWLGEEEEEERKGGGGGGGGARGRPNRAASCLTSPRIAWTPASPALHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYG2</accession>
    <name>C1MYG2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41121</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060824.1">
        <property type="nucleotide sequence ID" value="XM_003060778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYG2"/>
    <dbReference type="GeneID" id="9685961"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41121"/>
    <dbReference type="OMA" id="DARGPME"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="163" mass="15196" checksum="CE9B4C59B2697373" modified="2009-05-26" version="1">MSTSIAGGSSAVGGSSSSAASASSSSSSSASASASGGSAFSGSTGVVAGASSSAAGASGSGAAAAGSGSSGFAGSSAGAASTFGGVFSAAAVGSGGAEPGGGIGGGGRGDRSSIWVTTRREDARARRVRGGGDDDARGPMEEQNVRERRRRRRSRAAHLFPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYJ9</accession>
    <name>C1MYJ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59925</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060288.1">
        <property type="nucleotide sequence ID" value="XM_003060242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYJ9"/>
    <dbReference type="GeneID" id="9686018"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59925"/>
    <dbReference type="eggNOG" id="KOG3116">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="437973at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13917">
        <property type="entry name" value="zf-CCHC_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="19535" checksum="C80A18462897386C" modified="2009-05-26" version="1">MWRARPSGGGGAGTAAGAGGRPQCQRCLKFGKWTFECCKDASSRVYVSRPSRTAQLKNPKVRQRFADAADQPPDLRKEEKERRAAIIGKVKGPRAKRHRRSIDRSDRAGDERADRARARRSRARTRARCSRRRRRRRRRQVRAGGARADGDRRAGAVCGGVPSPPPLRSKVVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYK5</accession>
    <name>C1MYK5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_47835</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060583.1">
        <property type="nucleotide sequence ID" value="XM_003060537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYK5"/>
    <dbReference type="STRING" id="564608.C1MYK5"/>
    <dbReference type="GeneID" id="9685739"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47835"/>
    <dbReference type="eggNOG" id="ENOG502S8TT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GLAMESF"/>
    <dbReference type="OrthoDB" id="4214675at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050417">
        <property type="entry name" value="Sugar_Epim/Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43489:SF7">
        <property type="entry name" value="3-DEHYDRO-D-GULOSIDE 4-EPIMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43489">
        <property type="entry name" value="ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="3">
        <location>
            <begin position="118"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="390" mass="42172" checksum="6C446C02F035435A" modified="2009-05-26" version="1">MSSTFATCAARATLPSPLSSRRRRDGAPRASRARVALASSSSSSSSSSRSDRDSKPDRKSDAIPPLAKAQAPSFDERRATDDPDRPPAPITPNKLGVHALVFTGAWDEPAATLACAGAKRAGYDIIEIPLLSPSAVDGAMTKRVVEAHGLQATTSLGLRFDADVSSADDEIAARGEALLNDALEKTIQMGGTHMCGILYSALGKYDKPVTKRGYENSIAAIKRVARRANDAGVILGLEVVNRYETNVLNTAAQAMEFISEVNEDNVRVHLDSYHMCIEERSLRQAVNTCGDKLGYVHVGESHRGQLGTGNVDFCRLFYGLAEIQYRGPITFESFSGKVVSEDLSNTLCVWRDLWEDSDALAKHARDYVERAIEAAAGAHDNTRVIVGDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYW7</accession>
    <name>C1MYW7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_7192</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061112.1">
        <property type="nucleotide sequence ID" value="XM_003061066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYW7"/>
    <dbReference type="STRING" id="564608.C1MYW7"/>
    <dbReference type="GeneID" id="9686551"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7192"/>
    <dbReference type="eggNOG" id="KOG0838">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YQHVRHH"/>
    <dbReference type="OrthoDB" id="270651at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18096">
        <property type="entry name" value="SpoU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051259">
        <property type="entry name" value="rRNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191:SF7">
        <property type="entry name" value="OBP33PEP LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="3">
        <location>
            <begin position="2"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="184" mass="20028" checksum="76C54F10E208586F" modified="2009-05-26" version="1" fragment="single">YFIVHNIAKKHNVGTIARCATAFGVRAVVLVGAKAYNTFGCKGASNHVDFLHYPSLHAAREGLTAPPHRVRKIMGVEIMDDAVAIDERPFEGSTAFIMGNEGDGLTDAQKAICDGFVYIRQHGVGTASLNVSVAASIVMHHFALWAAYPERGREGEKFVVAERRLRTAKRGVVGDAPEEVRARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZU6</accession>
    <name>C1MZU6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Resistance-nodulation-cell division superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_48131</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the dispatched family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061014.1">
        <property type="nucleotide sequence ID" value="XM_003060968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZU6"/>
    <dbReference type="STRING" id="564608.C1MZU6"/>
    <dbReference type="GeneID" id="9686721"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48131"/>
    <dbReference type="eggNOG" id="KOG3664">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PFFYCRI"/>
    <dbReference type="OrthoDB" id="429851at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052081">
        <property type="entry name" value="Dispatched_Hh_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45951">
        <property type="entry name" value="PROTEIN DISPATCHED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="10" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="469"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="671"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="981"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1005"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1038"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1080"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1110"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="9">
        <location>
            <begin position="388"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="562"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="570"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="588"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="633"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1156" mass="125951" checksum="E7ED9A59A51B0573" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N085</accession>
    <name>C1N085_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_19761</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061082.1">
        <property type="nucleotide sequence ID" value="XM_003061036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N085"/>
    <dbReference type="STRING" id="564608.C1N085"/>
    <dbReference type="GeneID" id="9686792"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19761"/>
    <dbReference type="eggNOG" id="ENOG502QSHE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VAWVGSE"/>
    <dbReference type="OrthoDB" id="3501663at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912290" evidence="2">
        <location>
            <begin position="27"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase 3" evidence="3">
        <location>
            <begin position="140"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="644" mass="67532" checksum="318D1E93617E2DAD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0U6</accession>
    <name>C1N0U6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_20290</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061454.1">
        <property type="nucleotide sequence ID" value="XM_003061408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0U6"/>
    <dbReference type="STRING" id="564608.C1N0U6"/>
    <dbReference type="GeneID" id="9687138"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20290"/>
    <dbReference type="eggNOG" id="ENOG502QU6Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CFLKDYA"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF2">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="475" mass="51492" checksum="50E6A49D255E679E" modified="2009-05-26" version="1">MRAERLSRLAALEAGHRAASSAPPLSICDGDGDAEEDEEEAARRDGCAARLPLVPDGCAAAESDDRAAAGDAATPSASGGGHGGEPEPHPPPPLGLLNRPRQCYACKRRYRELHAFYASLCPECADLNWTKRRQTADLRGRVCVVTGARVKIGYRIALKLLRCGATVVATTRFPADATSRFEREADHETWRDRLAVCAMDLRDLPGLERLCERFVETLPRLDVIVNNACQTVRRPPAYYAHLLAKEAEAEAGGMRCVLYTGWMAPSAAASQLSVLPGDALDASTAAKHFPAGALDVNGQQVDLRMKHSWTMKLGEVETPELLEVLAVNAAAPFVLNGKLRALMARTAAMGRRDPADARAFIVNVSAMEGKFYRHKTANHPHTNMAKAALNMMTATAAADYAADRIYMNSVDTGWINDENPLETAARIARDHAFQTPIDEEDAAARCLAPVIEGCVPGSGTPPFGKFFKDYRESEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N166</accession>
    <name>C1N166_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63022</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061515.1">
        <property type="nucleotide sequence ID" value="XM_003061469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N166"/>
    <dbReference type="GeneID" id="9687197"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63022"/>
    <dbReference type="OMA" id="GFDWEAY"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="653" mass="68423" checksum="F946D4C0C0A7426C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N186</accession>
    <name>C1N186_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51305</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061769.1">
        <property type="nucleotide sequence ID" value="XM_003061723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N186"/>
    <dbReference type="GeneID" id="9686964"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51305"/>
    <dbReference type="OMA" id="PRTFERQ"/>
    <dbReference type="OrthoDB" id="10566837at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="164" mass="18601" checksum="91C6F18E44BD336E" modified="2009-05-26" version="1">MTSETSSETSSEVGASPTSEEEWVNPFPVPREPGHQVPRTFERQEAGTHVQIKLANEEFGQRMDVQEMMMKVMQATICSCPEDPLQFITDYLERELTGEGNEAIKNGFVDPNETNVHDYAGNVKFQIVLHRLSSALIEFKPEGDPLSFAVEYLKKLKEDPEPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N213</accession>
    <name>C1N213_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_41978</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus outer membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TMEM53 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062010.1">
        <property type="nucleotide sequence ID" value="XM_003061964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N213"/>
    <dbReference type="GeneID" id="9687450"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41978"/>
    <dbReference type="OMA" id="PLYLMFM"/>
    <dbReference type="OrthoDB" id="564271at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005640">
        <property type="term" value="C:nuclear outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008547">
        <property type="entry name" value="DUF829_TMEM53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265:SF30">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05705">
        <property type="entry name" value="DUF829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="288" mass="32505" checksum="5A1CBFE67BC05D15" modified="2009-05-26" version="1">MPRLDDKFKVESPSIPQNASFVVLCGWYKAKDAQLKRYSDVLRANGAVVLRTIMPPEDVYTLRESKRIENARALLAATREVRDARGYQELPLYLMFMSNGGCNFHAAMSSEKMLSDEGEFADLHHAIDVLGGGLIFDSCPCYLDTKIATKVFTMGMPSALARVASCAFRLSCALAAAANFVTRGYAPPLQYEPFWRKVRDAPPRRELYLFSEADDICVADKVDELVRERVRAGAAVKAKRWEKGRHVAHLYGENRKEYLALIEEFMRPSRMSCGLEFYLGEFSDVVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2W1</accession>
    <name>C1N2W1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_11074</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062274.1">
        <property type="nucleotide sequence ID" value="XM_003062228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2W1"/>
    <dbReference type="STRING" id="564608.C1N2W1"/>
    <dbReference type="GeneID" id="9687943"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11074"/>
    <dbReference type="eggNOG" id="KOG0589">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YKCHYGE"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="7"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="288" mass="32315" checksum="766059FA35A5FB24" modified="2009-05-26" version="1" fragment="single">PTVVGPYEVTRKIGEGGYGKIFLARRLARRVGRAIDDDEVVLKQVKLPTKKLEREMCLREVSIMKGAHHPCVLECTESFVDGGSVYIAMPHCTGGDLASLLRRHKKRGRRVPERVVLDWFAQIILGVEHLHSHDTLHRDLKSQNVFLRRDHLPVAGGAHRDEGAHASHHRGRSRVALGDFGIARELRFDDGGGGADAMARTFVGTPVFMAPEMFKRKPYDHKADVWAAGCVLYEMMQLSEPFRARTMGELTRLKPKPLPSEYGADLRDLCARMLAKNPDDRPTAREVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2X5</accession>
    <name>C1N2X5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51955</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062282.1">
        <property type="nucleotide sequence ID" value="XM_003062236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2X5"/>
    <dbReference type="GeneID" id="9687949"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51955"/>
    <dbReference type="OMA" id="VNDEACD"/>
    <dbReference type="OrthoDB" id="10643662at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02142">
        <property type="entry name" value="McbC_SagB-like_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="entry name" value="NADH Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052544">
        <property type="entry name" value="Bacteriocin_Proc_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43745">
        <property type="entry name" value="NITROREDUCTASE MJ1384-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43745:SF2">
        <property type="entry name" value="NITROREDUCTASE MJ1384-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="FMN-dependent nitroreductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="171"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="485" mass="51647" checksum="D1DB58A684664188" modified="2009-05-26" version="1">MRVRAVRAVRVPPLAPASVARSRRAAIRRARLPARAPPTPRVFSFEGEAATEDVLESSADRGEPSTTTTTTTTTMKTTTAPRAARSSSAAHAGTRAVEERPGAPPTPSARYPTVTAVDYEKVPPNATRLPPPDLHGHDSPRFEEGPSLSIPALGAFQLHLTPFNSTVEEVISRRRSCRDFAPPPLGLVHLYEIAQLCWAGQGLTAPEEAPDKYGHAGAASRAAPSGGCLYPLNLYVVVAPGGRVGGLDPGAYRYLPASHALCALSPKGDERCADDAASRRATRRTPNHTFVFDTWKYCNSIRIHQSRTRATDTRASSSHCRAEIENLGEAVCFDAAAADGVHGALARSTSAQANSTEYQTWIDDSAVVVLVTGNVRATAKHGGLYRRFATELVTTEAGMVAENVVLQATSLGLGATPIGAFDARAIHRTLPLKETGEDPLVMLAVGVPKGSFREHHGHGRAEDEQSARAAEVAAKGEETARRTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3A2</accession>
    <name>C1N3A2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_7787</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062574.1">
        <property type="nucleotide sequence ID" value="XM_003062528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3A2"/>
    <dbReference type="STRING" id="564608.C1N3A2"/>
    <dbReference type="GeneID" id="9687784"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7787"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.320">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="127" mass="14481" checksum="91697903CAA799AE" modified="2009-05-26" version="1" fragment="single">PHGPMAKIILWDQIARNCFRGTAKAFEFDDKALELARTMARDDDLVEKLPPAYVHFVCSPFTHSERIEDHDLGFHVYEGLAKRCPEVAGFAEGAMKSHRDVIARFGRYPHRNAKQGRESTAEELAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3M3</accession>
    <name>C1N3M3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52227</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062641.1">
        <property type="nucleotide sequence ID" value="XM_003062595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3M3"/>
    <dbReference type="STRING" id="564608.C1N3M3"/>
    <dbReference type="GeneID" id="9688081"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52227"/>
    <dbReference type="eggNOG" id="KOG0717">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="495069at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044648">
        <property type="entry name" value="JJJ1_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45495">
        <property type="entry name" value="DNAJ PROTEIN JJJ1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45495:SF1">
        <property type="entry name" value="DNAJ PROTEIN JJJ1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="9"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="94" mass="10529" checksum="1AEC752C640066FE" modified="2009-05-26" version="1">MQRPQRVRSHYDILGVARDASLDDLKRAYRKLALVLHPDKRVDGVSEEEAVVRFQTLVEAFKVRSVTGGDAGGRRNGSPRTAPAIRIEDKSESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3Z3</accession>
    <name>C1N3Z3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52350</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062457.1">
        <property type="nucleotide sequence ID" value="XM_003062411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3Z3"/>
    <dbReference type="GeneID" id="9688142"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52350"/>
    <dbReference type="OMA" id="HTNETTA"/>
    <dbReference type="OrthoDB" id="498809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="227" mass="22870" checksum="74668643D01967EA" modified="2009-05-26" version="1">MRRAIALAARRALVAAEPLAGADATRTTTTRARVLAPLAFHATQTRDLSARARGRSRGSRRAVGARPPPPAGGDPNDPWERVEDRATGQIYWWNVQTNETTPLGAPKPPPGTSANVPTTTGGHPSHPPAQQQQQSRGILGGLGSIVAEGMAFGTGSALAHRAIGSMFGGGGYGGGGGAAPAPGGEAPSDAAAAAGSEAGGGWGDDFDDVDDSGGGFFDGFDMGDFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4B3</accession>
    <name>C1N4B3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66717</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062758.1">
        <property type="nucleotide sequence ID" value="XM_003062712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4B3"/>
    <dbReference type="GeneID" id="9688411"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66717"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="186" mass="20813" checksum="9139230AB30C972C" modified="2009-05-26" version="1">MAHPGRARGDPSDRGGDSRRAAAAVGAARRGGGPEGRAAVPDPRPDPRAGDGRDHAVDLPGRKRRRGPNRRRRRRRRRRRRRRDAPRARAVRSPQPPALRRAPPPLPPGAPPRRRRPRARRRALRARQPRPLRVRRPSRRRASTRARAAVRASPAAGPPRPRVRSLPRPPRADVRGDQGAMSARRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4I5</accession>
    <name>C1N4I5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_52565</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063003.1">
        <property type="nucleotide sequence ID" value="XM_003062957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4I5"/>
    <dbReference type="GeneID" id="9688238"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52565"/>
    <dbReference type="OrthoDB" id="10632680at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910754" evidence="2">
        <location>
            <begin position="38"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="3">
        <location>
            <begin position="62"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="779"/>
            <end position="799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="827" mass="83364" checksum="C830BCC474508C0E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4L0</accession>
    <name>C1N4L0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52598</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062809.1">
        <property type="nucleotide sequence ID" value="XM_003062763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4L0"/>
    <dbReference type="GeneID" id="9688249"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52598"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="94" mass="9489" checksum="DE7FFE4F8369B224" modified="2009-05-26" version="1">MPRGGNAAASSSSPAPAPGDGGGVVIPGINDGTLHGGDTVFYLGAHDDAKETHRVKPVCGTALMFRHGAACAPHASEAVQRGIKIVLRSDVVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4P0</accession>
    <name>C1N4P0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribonuclease Z</fullName>
            <ecNumber evidence="4">3.1.26.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_71073</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase Z family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="4"/>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063032.1">
        <property type="nucleotide sequence ID" value="XM_003062986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4P0"/>
    <dbReference type="STRING" id="564608.C1N4P0"/>
    <dbReference type="GeneID" id="9688472"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_71073"/>
    <dbReference type="eggNOG" id="KOG2121">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QCVWISH"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990180">
        <property type="term" value="P:mitochondrial tRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07718">
        <property type="entry name" value="RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047151">
        <property type="entry name" value="RNZ2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553:SF70">
        <property type="entry name" value="RIBONUCLEASE Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="12">
        <location>
            <begin position="539"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="114"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="178"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="654"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="200"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="661"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH52971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="866" mass="90424" checksum="5A8A6A368F38A602" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N552</accession>
    <name>C1N552_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acyl-[acyl-carrier-protein] hydrolase</fullName>
            <ecNumber evidence="11">3.1.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_52801</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Plays an essential role in chain termination during de novo fatty acid synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Plastid</location>
            <location evidence="1 11">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the acyl-ACP thioesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.-" evidence="11"/>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062912.1">
        <property type="nucleotide sequence ID" value="XM_003062866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N552"/>
    <dbReference type="STRING" id="564608.C1N552"/>
    <dbReference type="GeneID" id="9688546"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52801"/>
    <dbReference type="eggNOG" id="ENOG502QTE3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WVITRIH"/>
    <dbReference type="OrthoDB" id="618395at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016297">
        <property type="term" value="F:fatty acyl-[ACP] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049427">
        <property type="entry name" value="Acyl-ACP_TE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002864">
        <property type="entry name" value="Acyl-ACP_thioesterase_NHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045023">
        <property type="entry name" value="FATA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31727">
        <property type="entry name" value="OLEOYL-ACYL CARRIER PROTEIN THIOESTERASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31727:SF6">
        <property type="entry name" value="OLEOYL-ACYL CARRIER PROTEIN THIOESTERASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01643">
        <property type="entry name" value="Acyl-ACP_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20791">
        <property type="entry name" value="Acyl-ACP_TE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10 11" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 11" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-ACP thioesterase N-terminal hotdog" evidence="13">
        <location>
            <begin position="108"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-ACP thioesterase-like C-terminal" evidence="14">
        <location>
            <begin position="289"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="371"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="17"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF20791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH52851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="405" mass="44784" checksum="59C987376BF4AC49" modified="2009-05-26" version="1">MAVPALATAQTATIRVSSRARAPRASAASSSRGASPTTPSSPVTMKASSSARASASSGPCATSKVRPRSRTRLRAIESDTARSAKQHAVDTDLEVPEWHSRSLIEDGRAFTETFPVRFDEVGPNKKTTMRTIASMLQECACNHAQGIWGRSQAMPADMKAQNLGWVCTRLHIVVDEYPAWGDMVEVRTWFDSQGKIAARRDWDMYYCTGDEEPNEQCASVGRATSQWVAFNIAKRKLARIPATVIPQFREQARKTRALKNTPVMGDDYDPDKLPDVREMSGAIAPTTQSVRRNDLDMNGHVNNVVYTEWLLEAVPHYMWNEFELTELVLEFREECGYGDLVDAVSANEKRVRTEFGQENAGVSMAHMLLRKSKGGSGDGAPTEVVRARTVWKARPRSPDLPAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5M2</accession>
    <name>C1N5M2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDP-D-glucose phosphorylase 1</fullName>
            <ecNumber evidence="5">2.7.7.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_63706</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GDP-alpha-D-glucose + phosphate = alpha-D-glucose 1-phosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:30387"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:62230"/>
            <dbReference type="EC" id="2.7.7.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GDPGP1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.78" evidence="5"/>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063182.1">
        <property type="nucleotide sequence ID" value="XM_003063136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5M2"/>
    <dbReference type="STRING" id="564608.C1N5M2"/>
    <dbReference type="GeneID" id="9688827"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63706"/>
    <dbReference type="eggNOG" id="KOG2720">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="417175at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080048">
        <property type="term" value="F:GDP-D-glucose phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026506">
        <property type="entry name" value="GDPGP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058865">
        <property type="entry name" value="GDPGP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058866">
        <property type="entry name" value="GDPGP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20884">
        <property type="entry name" value="GDP-D-GLUCOSE PHOSPHORYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20884:SF8">
        <property type="entry name" value="GDP-D-GLUCOSE PHOSPHORYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26216">
        <property type="entry name" value="GDPGP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26217">
        <property type="entry name" value="GDPGP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GDPGP1-like N-terminal" evidence="15">
        <location>
            <begin position="140"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="GDPGP1-like C-terminal" evidence="14">
        <location>
            <begin position="350"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="531"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF26216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF26217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH52318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="607" mass="64026" checksum="FE59BF60870E9EB1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N609</accession>
    <name>C1N609_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63829</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063456.1">
        <property type="nucleotide sequence ID" value="XM_003063410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N609"/>
    <dbReference type="GeneID" id="9688895"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63829"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF12">
        <property type="entry name" value="AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="670" mass="71344" checksum="3DA0429169960921" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7C7</accession>
    <name>C1N7C7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_30002</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063713.1">
        <property type="nucleotide sequence ID" value="XM_003063667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7C7"/>
    <dbReference type="STRING" id="564608.C1N7C7"/>
    <dbReference type="GeneID" id="9689317"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30002"/>
    <dbReference type="eggNOG" id="KOG0894">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FTNYHPE"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="5"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="150" mass="16706" checksum="70ED2AC059D09B9F" modified="2009-05-26" version="1" fragment="single">MSKKTSKVRLQKEMRAFVQDPPPFIPRVHVNERNMLEWHLLMEGPHGTPFEDGWYVAKLKFPGEYPFKPPSIFMCTPNGRFATGTRLCLSMSDFHPESWNPGWSVATVAKGLLSFMLEDAVTTGAVVTTGVEQDARDVQGDVPGARGRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7E1</accession>
    <name>C1N7E1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65966</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063719.1">
        <property type="nucleotide sequence ID" value="XM_003063673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7E1"/>
    <dbReference type="STRING" id="564608.C1N7E1"/>
    <dbReference type="GeneID" id="9689160"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65966"/>
    <dbReference type="eggNOG" id="ENOG502QSEG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YHFPRYP"/>
    <dbReference type="OrthoDB" id="497615at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053285">
        <property type="entry name" value="Thylakoid_lumenal_pentapeptide"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47121">
        <property type="entry name" value="THYLAKOID LUMENAL PROTEIN TL20.3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47121:SF2">
        <property type="entry name" value="THYLAKOID LUMENAL PROTEIN TL20.3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="277" mass="28676" checksum="ADFC7E7041BAE5E4" modified="2009-05-26" version="1">MALVLGGNARVARAPRAVVAAKKTRKTVGAARCRASSSSSSSSDDDAVVVASVGTTTTTSWIDRAKGVATAACAAAALLVSSPAAHAELNAREANRGGEFNRGSAQQFGGYDLRNEDVVGKYGADLRLSNFTGAEMRGAKLRGANLTGAYLMKAVAFEADFEGANLSDALMDRAVLNSANFRDAILTRVVLTSSDLGDAKIDGADFSDALIDKSQQQKLCQYASGTNSVTGVSTRRSLNCGGGVRTSSPSRYMTDETSAKPEAAFDASRFSAYGTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7N7</accession>
    <name>C1N7N7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53771</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063936.1">
        <property type="nucleotide sequence ID" value="XM_003063890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7N7"/>
    <dbReference type="STRING" id="564608.C1N7N7"/>
    <dbReference type="GeneID" id="9689377"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53771"/>
    <dbReference type="OrthoDB" id="498670at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="191" mass="20504" checksum="3435891EAB5BAB90" modified="2009-05-26" version="1">MDPRPSARLTSLQRSLRDLVFQRWLDGRCEDRADTHKAVGAVDLFVPFFPLDRAAVEAVVASHLRRVLSHTGPHTTALAWARSVRRARAGELRGLSWDTRVIEFLASQVEFERGYAIEGGKEAPAVLSRFVTRAIRKLTTARGGGGGGGGGGGLSGARVRLAVADDGNELVASVESEEEEEEEARAAAGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8A1</accession>
    <name>C1N8A1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43279</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064045.1">
        <property type="nucleotide sequence ID" value="XM_003063999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8A1"/>
    <dbReference type="GeneID" id="9689675"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43279"/>
    <dbReference type="OMA" id="GAGNHMA"/>
    <dbReference type="OrthoDB" id="10687528at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014840">
        <property type="entry name" value="HRD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08729">
        <property type="entry name" value="HUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hpc2-related" evidence="2">
        <location>
            <begin position="116"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="509" mass="52696" checksum="077BC8E419D15BBF" modified="2009-05-26" version="1">MASLRMGGAPPAKANKNAKNGATTGAGNHMAAVIRRIEGFYSAPRCRDSDDDDDEDDEPERENVDDDDDDDDDDDDDASASEGEEIDPNDADAVAAQQARREAKKAAKAKAKAEQKKKRSAGGGYEEWYDLDDDFIDDEELDEYFEENGRKDKLGGKGGDRFYVNKGDIEFVDDGTGAAAAHDRAKRMKMTTVGGGGSKSENFGDFSPEDASLAGNQRAAGLKWSEHEMATLTKGVQRHGRKWMTIKRDREFAPTLRAFSNAAMKARSISTLHKWKMMVREQARANAAGLVAGGGGAGGDGAGAGAGAAGSGSVATAPSPPARPPPEPAPAPQPATAPPPATAPSPADAATVAAMQRAMAAANAAAALRGSPITPAGVTPSPPTDSGGGAAGAGAGAAIKTFVVSKSTASSWTSVHGANGAWSPVLTAAIEDVRAVAETLTPPERGSEPGARLPPLPDALLVPLAEVVKIVKGGDGESALPRGLIKSLMEFMEPFCSATTLQRRMSMMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N982</accession>
    <name>C1N982_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54400</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064574.1">
        <property type="nucleotide sequence ID" value="XM_003064528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N982"/>
    <dbReference type="GeneID" id="9690015"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54400"/>
    <dbReference type="OrthoDB" id="566659at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="82" mass="9376" checksum="9E2CE0165F0BC265" modified="2009-05-26" version="1">MNIKSKKTAEWVGLPAWVVDGDVENVEWFNEVVRTVWPHVGAAAAQKIRSYIEPLLDHDKPKARSVVHWSPYDRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Q1</accession>
    <name>C1N9Q1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_49280</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the cullin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH50987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064653.1">
        <property type="nucleotide sequence ID" value="XM_003064607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Q1"/>
    <dbReference type="STRING" id="564608.C1N9Q1"/>
    <dbReference type="GeneID" id="9690215"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49280"/>
    <dbReference type="eggNOG" id="KOG2167">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NYQEQTW"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000001">
        <property type="entry name" value="Cullin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.130:FF:000001">
        <property type="entry name" value="Cullin 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000035">
        <property type="entry name" value="Ubiquitin ligase subunit CulD, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cullin family profile" evidence="4">
        <location>
            <begin position="440"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH50987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="729" mass="80949" checksum="C151FE7707CA7C13" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA34</accession>
    <name>C1NA34_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54746</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064719.1">
        <property type="nucleotide sequence ID" value="XM_003064673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA34"/>
    <dbReference type="GeneID" id="9690160"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54746"/>
    <dbReference type="OrthoDB" id="1726667at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="515" mass="55428" checksum="E0674797FFD4E7E9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA48</accession>
    <name>C1NA48_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine(9)-N(1))-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.221</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_7027</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>guanosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43156"/>
            <dbReference type="Rhea" id="RHEA-COMP:10367"/>
            <dbReference type="Rhea" id="RHEA-COMP:10368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.221"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.221" evidence="1"/>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064726.1">
        <property type="nucleotide sequence ID" value="XM_003064680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA48"/>
    <dbReference type="STRING" id="564608.C1NA48"/>
    <dbReference type="GeneID" id="9690289"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7027"/>
    <dbReference type="eggNOG" id="KOG2967">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YQIGFHV"/>
    <dbReference type="OrthoDB" id="278300at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052905">
        <property type="term" value="F:tRNA (guanosine(9)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18089">
        <property type="entry name" value="SPOUT_Trm10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028564">
        <property type="entry name" value="MT_TRM10-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038459">
        <property type="entry name" value="MT_TRM10-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007356">
        <property type="entry name" value="tRNA_m1G_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563">
        <property type="entry name" value="TRNA (GUANINE-9-) METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563:SF13">
        <property type="entry name" value="TRNA METHYLTRANSFERASE 10 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51675">
        <property type="entry name" value="SAM_MT_TRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase TRM10-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="160" mass="17615" checksum="C5C51F782414AA33" modified="2009-05-26" version="1" fragment="single">LKSLAKQLSFCYVANCRAATPCRLYLTGLTGAMGEVVERCCSGMANWAVIASEKPYIELLAEQKSKLVYLTADSENELTAFSEDDVYVIGGIVDRNKHKNLTLDKANAQGIRHARLPIRDHLKMTGSHVLTVNQTLDIAHAQMELGDWAAALDRAVPTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAJ4</accession>
    <name>C1NAJ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_66097</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064920.1">
        <property type="nucleotide sequence ID" value="XM_003064874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAJ4"/>
    <dbReference type="GeneID" id="9690360"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66097"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH50900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="96" mass="10734" checksum="CD090BE41FF7901A" modified="2009-05-26" version="1">MISEIRTRHEGQLLLLHGTVIRVGIVQSRDANQLNECIECKHRFFVESEAADLLATCPSASVLFQHVNSSISTCNCTTFCRLVLLVQIARLSRAIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHJ7</accession>
    <name>C1MHJ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50222</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055505.1">
        <property type="nucleotide sequence ID" value="XM_003055459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHJ7"/>
    <dbReference type="GeneID" id="9680258"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50222"/>
    <dbReference type="OMA" id="ANDFMVL"/>
    <dbReference type="OrthoDB" id="550279at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35750">
        <property type="entry name" value="PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35750:SF1">
        <property type="entry name" value="PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="156" mass="17228" checksum="2E730BA40828D700" modified="2009-05-26" version="1">MNFLKRGFKAAKSFIVGVRPRLPFARLVVVEAGNLTRVLSPPPIHAQDDDGSDDSGNEGGGFSHKKQVVVERPRIPVVQYAVSRYGGEPMGGVQGLWWYVKELKIDDDGDIANDFMVLDGDGKDVNEGEERRYKQANVEIRGVSRGNLLLAPYTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHM0</accession>
    <name>C1MHM0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ethanolamine kinase</fullName>
            <ecNumber evidence="3">2.7.1.82</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50248</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.82" evidence="3"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054979.1">
        <property type="nucleotide sequence ID" value="XM_003054933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHM0"/>
    <dbReference type="STRING" id="564608.C1MHM0"/>
    <dbReference type="GeneID" id="9680699"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50248"/>
    <dbReference type="eggNOG" id="KOG4720">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YEAQMCE"/>
    <dbReference type="OrthoDB" id="197421at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF66">
        <property type="entry name" value="ETHANOLAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="364" mass="40756" checksum="18A788D5267225E4" modified="2009-05-26" version="1">MACSALITAADWHAHHARSRHRESRARRSRAASGTGRYEESIRRVVNADNTARLRSEELSKGFCNSVHLVRGVNGDDEALVVKLYSDLSLLRTESDQRGAVDKIASVFGLGPTVWSSTHEGIAHSFVPGRVLEEVDMHTRSDVGVAAARLVARFHSLQVPREFDAERQPLLWKWFDRMLDEIGESDDVGVLPDSVNLDVLRAEVKEMRESITSAGEMFTVVLAHGDLKPANVMLQNDAPVELKLIDLELSGPNYRGFDLMKLFRTNSETFSEEKFAAFLSEYCRAARLDENAVRNIEAETKLFEPLTWLEAAVFFALVVVLGTDAGGPSGDSARWLDLLHSRYDSYLETRQLFAHHMSQLTRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHN2</accession>
    <name>C1MHN2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_12807</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055521.1">
        <property type="nucleotide sequence ID" value="XM_003055475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHN2"/>
    <dbReference type="STRING" id="564608.C1MHN2"/>
    <dbReference type="GeneID" id="9680572"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12807"/>
    <dbReference type="eggNOG" id="KOG4280">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ERCQINT"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030705">
        <property type="term" value="P:cytoskeleton-dependent intracellular transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115:SF9">
        <property type="entry name" value="KINESIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115">
        <property type="entry name" value="KINESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="3">
        <location>
            <begin position="9"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="91"/>
            <end position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="350" mass="38122" checksum="F4F219872B172D91" modified="2009-05-26" version="1" fragment="single">MPAAAEDERVRVFARIRPPQASTLTAAATTKRDDRRVTVSNPTAAISSRREFRVDKVFDATATNEDVYLGVGAPILDAVLAGCHGSILAYGQSGSGKTYSMLNDDGDVAAAGIVPRAAVDLFKRVRFDQAYVYDIAISMVQIYNETAIDLLTNSGASLKATQRKDGAGGFELADCEWRHCRDAVDLLGNFRRGRTNLIYAETKMNRHSSRSHCVLLVRVNRVSRAASSSTDESTGCKLYTQLQGLLTIVDMAGSERAKKSQSQGVRFNEATHINGSLLTFGNVVHALAEKQMHVPFRDSMLTKLLESSLSGRSRTALIVCVAPETEHAHESITSLELAARCMRVESRPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHR8</accession>
    <name>C1MHR8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50298</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055002.1">
        <property type="nucleotide sequence ID" value="XM_003054956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHR8"/>
    <dbReference type="GeneID" id="9681108"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50298"/>
    <dbReference type="OrthoDB" id="126772at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910464" evidence="1">
        <location>
            <begin position="24"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="182" mass="19190" checksum="B1293003D7F6BA27" modified="2009-05-26" version="1">MALADVLLRLALIALLRVGKARADTAVGSRARANATAGSIVSTNATKARASSPAPAPLADADASDDLFACRIVCREERWSPTCCANGTYANGCWNACAISALRRPSCVATPGRCEPSRERFRANDGCVQDCVVDWARTGYAWQDMACGEDGTTYTTACFARCSNVAYTLGECHDVGGGRRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI40</accession>
    <name>C1MI40_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamate-5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="2">1.2.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_30966</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="2"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055063.1">
        <property type="nucleotide sequence ID" value="XM_003055017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI40"/>
    <dbReference type="STRING" id="564608.C1MI40"/>
    <dbReference type="GeneID" id="9681168"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30966"/>
    <dbReference type="eggNOG" id="KOG4165">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KTQRYGT"/>
    <dbReference type="OrthoDB" id="1934954at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001221">
        <property type="entry name" value="PRK00197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063:SF8">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063">
        <property type="entry name" value="GLUTAMATE SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="9"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="464" mass="49729" checksum="8DAFBFED25B95DB8" modified="2009-05-26" version="1">MSTTREKAVAARAASRQLQNLSSDERAELLNRIADALEANEPAILRENELDLKKAAEDGTEPALMNRLKMKPGKIAQLAEGARQIARMEEPLVRPLSKMELADGLMLEQVTAPLGVLLIIFESRPDALPQIAALSIRSGNGLLLKGGKEAAKTNAILHRVIVECFPQFGVAKEAIVLVEGRAEIADILKLNDVVDLVIPRGSNDLVTYIQDNTKIPVLGHADGVCHVYVDPDADIDMACKLCVDSKCDYPAACNALETLLVHSSQLGAGGGYERVAAALDAAGVEKFGGARAAKELSLPPCPALRHEYGTLALTVEIVDSMDEAIEYIHANGSSHTDCIITKDKARAEEFLRRVDSACVFHNASTRFSDGFRFGLGAEVGISTSRIHARGPVGVEGLLTTRWLLRGKGQYSDKDTAVTYTHKKISIGGAWIKRAAEGITAAVGVVNAVNIGLMILAWKKGSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIH2</accession>
    <name>C1MIH2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SNF2 super family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_50566</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055131.1">
        <property type="nucleotide sequence ID" value="XM_003055085.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MIH2"/>
    <dbReference type="GeneID" id="9680248"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50566"/>
    <dbReference type="eggNOG" id="KOG1000">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TNRIHAY"/>
    <dbReference type="OrthoDB" id="2801544at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766:SF5">
        <property type="entry name" value="SNF2 DOMAIN-CONTAINING PROTEIN _ HELICASE DOMAIN-CONTAINING PROTEIN _ HNH ENDONUCLEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="252"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="669"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="571"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="878"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1032"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1268"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1319"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="583"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="882"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1037"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1054"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1270"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1364"/>
            <end position="1387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1408" mass="152408" checksum="685EC066069ECB3C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJT2</accession>
    <name>C1MJT2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64071</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056267.1">
        <property type="nucleotide sequence ID" value="XM_003056221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJT2"/>
    <dbReference type="GeneID" id="9681433"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64071"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="316" mass="34059" checksum="31766C32D1489C2D" modified="2009-05-26" version="1">MHLQVVSTRPDYVERSNTSISTHTLGARARERSRAREGVMSFADTLRNRAGAAGKPTRARDLAPGRGADDDDDDDDDDDDDDARDDRVGDDRRGARADAIANPAAARRADRGVSTWRDVAGIDRDRGGGTRDDDESDAARPSTARFSTGALRRVERVRCADPDAAADAANGGEADADAADADAADAGGGARVRATLPMDWALKSRVAFASSAPFRCLAARAGDGAGGDRGVRAFASGRARDAFNAEERESAAATIARASMTWQHPSSPMEPELVREMRATERGRAFHERRVDAWCVQYKRFSPIARFQHLITSLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK61</accession>
    <name>C1MK61_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_14310</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055940.1">
        <property type="nucleotide sequence ID" value="XM_003055894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK61"/>
    <dbReference type="STRING" id="564608.C1MK61"/>
    <dbReference type="GeneID" id="9681312"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14310"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WEIDAGY"/>
    <dbReference type="OrthoDB" id="515324at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="4">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="236" mass="24432" checksum="8D85E6769E722913" modified="2009-05-26" version="1" fragment="single">MFGFVGPSVVLDTACSSSLVAVHLAQHATARVEAVSAYAAGVQCTLLSGTFSVLNNLNALSPDGRCKTFDIAADGYGRGEAHAAIYTRLFNQSTSQVSKISTNAFITLSGSSVNQDGRASTFTAPFGPSQQVLALKALAEAAIEPNDIRYVSTHGTGTSLGDPIEISAAWRTLKLGRSGACIQSMVTTVGANKSFLGHTEGSAGISGLLMAVCVASNFGFPALRHCYNLNPYISSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK76</accession>
    <name>C1MK76_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64252</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055950.1">
        <property type="nucleotide sequence ID" value="XM_003055904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK76"/>
    <dbReference type="STRING" id="564608.C1MK76"/>
    <dbReference type="GeneID" id="9681927"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64252"/>
    <dbReference type="eggNOG" id="ENOG502SFMF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EINDPGW"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12861:SF3">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12861">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05753">
        <property type="entry name" value="TRAP_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910300" evidence="1">
        <location>
            <begin position="26"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="219" mass="24509" checksum="B097D826535385FA" modified="2009-05-26" version="1">MTAHAANFVRFAFIVFSLFFRVALAHDFTATRAHVILHKAVSAEPLVLGQNFTVTLTAYNRGNIDARSVDIIDAKYDPNVFTILNGASSIMSEFDVVEPGENATFSFELVATRLGVYTLTPAVVTYRASDGEQKTRGTSNDVENLWCVTEMDKSFERVFRIGAYLTLGLARNAEEWKKGAKITTGVLSLLTVNYVLLLLKQFRKEWERRRAIVSLTKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKA4</accession>
    <name>C1MKA4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55256</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056351.1">
        <property type="nucleotide sequence ID" value="XM_003056305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKA4"/>
    <dbReference type="GeneID" id="9681936"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55256"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="125" mass="14284" checksum="7CC55A9BA75ABF7D" modified="2009-05-26" version="1">MSDEVVSETHNVSDAARKTEETLRFYENFERDFEKNFSQADATDTDYSGSGSGSDENENENEDEDAWAERWEREQWAARNEKKTSKASPRRGVASRSLTVRQTPPRQPSALAVSVSARGQPRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKB5</accession>
    <name>C1MKB5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_64293</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056358.1">
        <property type="nucleotide sequence ID" value="XM_003056312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKB5"/>
    <dbReference type="STRING" id="564608.C1MKB5"/>
    <dbReference type="GeneID" id="9681324"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64293"/>
    <dbReference type="eggNOG" id="KOG2604">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DEFELWG"/>
    <dbReference type="OrthoDB" id="296793at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048685">
        <property type="entry name" value="COG3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048320">
        <property type="entry name" value="COG3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007265">
        <property type="entry name" value="COG_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302:SF8">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20671">
        <property type="entry name" value="COG3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04136">
        <property type="entry name" value="COG3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 N-terminal" evidence="10">
        <location>
            <begin position="122"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 C-terminal" evidence="11">
        <location>
            <begin position="294"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="497"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH59734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="819" mass="92963" checksum="D438F3867B60BFEB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKD8</accession>
    <name>C1MKD8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_49421</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. CGFS subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055979.1">
        <property type="nucleotide sequence ID" value="XM_003055933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKD8"/>
    <dbReference type="STRING" id="564608.C1MKD8"/>
    <dbReference type="GeneID" id="9681943"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49421"/>
    <dbReference type="eggNOG" id="KOG0911">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RNAPQCG"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF45">
        <property type="entry name" value="BIFUNCTIONAL MONOTHIOL GLUTAREDOXIN-S16, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="2">
        <location>
            <begin position="199"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="293" mass="33087" checksum="5F15BB624C72907E" modified="2009-05-26" version="1">MTTISSDFSVATALHRCPVPRNTRFCRGCRVVHLPSYSWKVRSATGDQLQYQGSSIIPIVSLSAADFSQVIFPEHPGIYAVYNTTMEIQYIGISRKISSSVKLHKYEMPRYCGFLRFAAIPRATKADLQLLWKQWMQEHLAVSGGLLPPGNVRGNSQWSRRKHLPPKINILLTNGVNSQVNDSTVFQLCREIVESYNIVAFIKGTRKEPECGFSYRVCAILEELSVDFETVDTLDERHNHNLRNVLKDFSDWPTIPQVYYRGSLLGGHDIIEDLYKSGQLKHILVPGSTAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKK0</accession>
    <name>C1MKK0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_55368</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MOZART1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056010.1">
        <property type="nucleotide sequence ID" value="XM_003055964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKK0"/>
    <dbReference type="GeneID" id="9681959"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55368"/>
    <dbReference type="OMA" id="GARDMRD"/>
    <dbReference type="OrthoDB" id="48571at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000931">
        <property type="term" value="C:gamma-tubulin ring complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031021">
        <property type="term" value="C:interphase microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033566">
        <property type="term" value="P:gamma-tubulin complex localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051415">
        <property type="term" value="P:microtubule nucleation by interphase microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022214">
        <property type="entry name" value="MZT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28520">
        <property type="entry name" value="MITOTIC-SPINDLE ORGANIZING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28520:SF2">
        <property type="entry name" value="MITOTIC-SPINDLE ORGANIZING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12554">
        <property type="entry name" value="MOZART1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="59" mass="6581" checksum="86AD0386F39B6535" modified="2009-05-26" version="1">MLSDFTAAFEISQLLECGLDKECLSILVALCENEINSEALVTVVYELRREAAVFRGELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLF0</accession>
    <name>C1MLF0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_31857</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056155.1">
        <property type="nucleotide sequence ID" value="XM_003056109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLF0"/>
    <dbReference type="STRING" id="564608.C1MLF0"/>
    <dbReference type="GeneID" id="9682030"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31857"/>
    <dbReference type="eggNOG" id="KOG2187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GGCKWQH"/>
    <dbReference type="OrthoDB" id="10250660at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000009">
        <property type="entry name" value="23S rRNA (Uracil(1939)-C(5))-methyltransferase RlmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00479">
        <property type="entry name" value="rumA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="RNA M5U METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061:SF30">
        <property type="entry name" value="TRNA (URACIL(54)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="6">
        <location>
            <begin position="39"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="485"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="485"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="549" mass="59546" checksum="149F678667131235" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLI0</accession>
    <name>C1MLI0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_55722</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:14761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="EC" id="2.3.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="5"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056568.1">
        <property type="nucleotide sequence ID" value="XM_003056522.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MLI0"/>
    <dbReference type="GeneID" id="9681592"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55722"/>
    <dbReference type="eggNOG" id="KOG1357">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1358">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YRRMWRT"/>
    <dbReference type="OrthoDB" id="65434at2759"/>
    <dbReference type="UniPathway" id="UPA00222"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1256"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1298"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1330"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1360"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1390"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1430"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="12">
        <location>
            <begin position="144"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="12">
        <location>
            <begin position="608"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="565"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH59944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1617" mass="173584" checksum="66EB06559BB8BAC0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLU6</accession>
    <name>C1MLU6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Small conductance mechanosensitive ion channel family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_56273</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056826.1">
        <property type="nucleotide sequence ID" value="XM_003056780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLU6"/>
    <dbReference type="STRING" id="564608.C1MLU6"/>
    <dbReference type="GeneID" id="9682265"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56273"/>
    <dbReference type="eggNOG" id="ENOG502S0B8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FMPGDEI"/>
    <dbReference type="OrthoDB" id="567160at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056876">
        <property type="entry name" value="Msl2-3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045042">
        <property type="entry name" value="YnaI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43634:SF2">
        <property type="entry name" value="LOW CONDUCTANCE MECHANOSENSITIVE CHANNEL YNAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43634">
        <property type="entry name" value="OW CONDUCTANCE MECHANOSENSITIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24956">
        <property type="entry name" value="Msl2-3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="Mechanosensitive channel protein MscS (YggB), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="Mechanosensitive channel protein MscS (YggB), transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Mechanosensitive ion channel MscS" evidence="10">
        <location>
            <begin position="254"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Mechanosensitive ion channel protein 2/3 C-terminal" evidence="11">
        <location>
            <begin position="330"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="500"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF24956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="548" mass="60810" checksum="D6E0B84A938E1B36" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM10</accession>
    <name>C1MM10_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_56358</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057313.1">
        <property type="nucleotide sequence ID" value="XM_003057267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM10"/>
    <dbReference type="GeneID" id="9682297"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56358"/>
    <dbReference type="OMA" id="DVNLYWM"/>
    <dbReference type="OrthoDB" id="10403118at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="321" mass="35998" checksum="3AFD7F832A08586E" modified="2009-05-26" version="1">MESPPDDDAAPASSDAALLPVGHPVRVKRAGEWLDEWAEILAVKSPPIAESPVARYDVLVKPMIDVTTVSDERGPGVRDGDGNYFRLHTVWYVITDKPYPDEVVELTPETDPDAETKIRAYQKKYEQDGFMRKLYADEKRRTSEVTVRALMNADVERVAAAGPGRVDEVSVPVDVNLYWMKPVLEVMTKYRPTVAKGMTAGWHKPVTFFFHTDKSREAMKNNYEKVLMPSFREGLAPPGGKPLHGGKLYLDGKLLAEDPEKCGFPGYCYEYQHVCVWAVDEQVPFVFVPAGQNYDAEAWKAVYHGRREPPARGCMDACVAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM19</accession>
    <name>C1MM19_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_62352</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056862.1">
        <property type="nucleotide sequence ID" value="XM_003056816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM19"/>
    <dbReference type="GeneID" id="9682301"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62352"/>
    <dbReference type="eggNOG" id="ENOG502SAQJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="39387at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="89"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="184"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="240"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="191"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="261"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="271" mass="30283" checksum="B25A101038F4D1E7" modified="2009-05-26" version="1">MGVWGKKPAAPTPYDLVWGDGVVPSILFGMTALFMVLHPILRTMFPRTMRARGAFLLAFELSCLFPLAYCAYEGYTTWTTGLGAFTTAKARLYATSPGAVRVLQAHLAFEAWDFGVSFFNKTLRAPEMLAHHALAALLCYWALTMPYMHYYAVYFMGVAEISSVPLVLVDAGKYYPDVSKRFPGSTSRYGRTASRSSPRVTSRRSTPGTSPRACSSRTSSSARCRCCGRGSWREGCTTCLRRKPRPGRTRPRRSPTWTRRNASELKRESPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM76</accession>
    <name>C1MM76_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56426</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057351.1">
        <property type="nucleotide sequence ID" value="XM_003057305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM76"/>
    <dbReference type="STRING" id="564608.C1MM76"/>
    <dbReference type="GeneID" id="9682790"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56426"/>
    <dbReference type="eggNOG" id="ENOG502RZFG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5531344at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021067">
        <property type="entry name" value="Glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496:SF10">
        <property type="entry name" value="GLCNAC TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496">
        <property type="entry name" value="GLCNAC TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11397">
        <property type="entry name" value="GlcNAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="251"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="471" mass="51078" checksum="274D234DB86E5A36" modified="2009-05-26" version="1">MTDENDDGRRACPAGARVTLRLPSVISHSDAARDMTFTPAPTQAKRPSWASARDDPPADANTADAKPPPPPPRARRLEAPLLNALGLGAIFRDPDGRDDDADAAAARADETFTHKMCKMCGNVCNAKMTSCTSCCLPLTEPGSYAPATMPKPGAVASDDDATSEDDASSNEGDGDGDGAEPSSSSSPPPPSAMPSNAARAAMERRKLERRRAATEAATAEDEDDESAWWARGWRDLSPPTRARGHDPALRSAYDVLGLPLGAGEDDVRAAYRREARINHPDKGGEPEELERVHDAFDAIALDAWRHDDGARALRDALAAKKEGKRTDADATNGEDEPTRDDDSPPPPKIFVSVCVYRDPEAQFTLRDVFAKATRPERVFVGVSWRYKLPRPPSSSSAPVVIDRMHRDMAPLAYAIEREAAKIKDEEGQRKYLTECMDVQREAQAACDDVEAKVRSIHWSPYDRVGVVNADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMR0</accession>
    <name>C1MMR0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_38948</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056972.1">
        <property type="nucleotide sequence ID" value="XM_003056926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMR0"/>
    <dbReference type="STRING" id="564608.C1MMR0"/>
    <dbReference type="GeneID" id="9682888"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38948"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LKQVWDN"/>
    <dbReference type="OrthoDB" id="512346at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF34">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="458"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="66"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="519"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="545" mass="55425" checksum="C47C107B83375D56" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPA6</accession>
    <name>C1MPA6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Probable glutamyl endopeptidase, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_15371</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Serine-type protease active in vitro against the LHCII N-terminal. Cleaves its substrate on the carboxy-side of Glu residues.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast stroma</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase S9D family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057252.1">
        <property type="nucleotide sequence ID" value="XM_003057206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPA6"/>
    <dbReference type="STRING" id="564608.C1MPA6"/>
    <dbReference type="ESTHER" id="micpc-c1mpa6">
        <property type="family name" value="Glutamyl_Peptidase_S9"/>
    </dbReference>
    <dbReference type="MEROPS" id="S09.021"/>
    <dbReference type="GeneID" id="9682226"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15371"/>
    <dbReference type="eggNOG" id="KOG2100">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WAYPREY"/>
    <dbReference type="OrthoDB" id="43744at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000049">
        <property type="entry name" value="probable glutamyl endopeptidase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF28">
        <property type="entry name" value="GLUTAMYL ENDOPEPTIDASE, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="12">
        <location>
            <begin position="702"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH58897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="877" mass="95984" checksum="3F59B2DB2D9E934D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPG6</accession>
    <name>C1MPG6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_46915</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057954.1">
        <property type="nucleotide sequence ID" value="XM_003057908.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MPG6"/>
    <dbReference type="GeneID" id="9683392"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46915"/>
    <dbReference type="eggNOG" id="KOG0597">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FLTHIYR"/>
    <dbReference type="OrthoDB" id="24822at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000914">
        <property type="term" value="P:phragmoplast assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14010">
        <property type="entry name" value="STKc_ULK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056980">
        <property type="entry name" value="ARM_RUK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056981">
        <property type="entry name" value="HEAT_ULK4_RUNKEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044591">
        <property type="entry name" value="RUK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46562">
        <property type="entry name" value="SERINE/THREONINE-KINASE ULK4-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46562:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ULK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24970">
        <property type="entry name" value="ARM_RUK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23606">
        <property type="entry name" value="HEAT_ULK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="4"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="1">
        <location>
            <begin position="778"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="313"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="365"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="817"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1089"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="365"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="450"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="486"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="546"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="590"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1090"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1592" mass="166786" checksum="080961D06D8C2AB9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPG7</accession>
    <name>C1MPG7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_56898</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057574.1">
        <property type="nucleotide sequence ID" value="XM_003057528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPG7"/>
    <dbReference type="STRING" id="564608.C1MPG7"/>
    <dbReference type="GeneID" id="9683393"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56898"/>
    <dbReference type="eggNOG" id="KOG0075">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PRECKIP"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732:SF7">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="26"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="184" mass="20523" checksum="CCCDFC2DCEC6817C" modified="2009-05-26" version="1">MGPWERLIETVFVRPKRPRVELAVTGLPGAGKTSFAHVLATGSFDPATLPSRAHTYDMTTITKEGFALKVWDVARGGAFQTRWERYCRNCRAVVFVFDASDRDVSHITDAREALHDLMRRSTLHNVPLLVLGNKSDRKNAMTAGECADALRLDDCASVSCARLDGLDYAMDWLAREATPKVKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPQ2</accession>
    <name>C1MPQ2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_56994</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC43A transporter (TC 2.A.1.44) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057621.1">
        <property type="nucleotide sequence ID" value="XM_003057575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPQ2"/>
    <dbReference type="GeneID" id="9683431"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56994"/>
    <dbReference type="eggNOG" id="ENOG502SAB3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LQMIRMN"/>
    <dbReference type="OrthoDB" id="330047at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF2">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="245"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="475" mass="49575" checksum="A596094957265299" modified="2009-05-26" version="1">MPLLERRWGLYSLAFALTSLVAGTVYGWPALRRDLVREGGLTEKELGAVFLAGSWSVNGCRLFSGLARDRFGTRVTACGVLLLCLVGVLLVAFSSSGSFWGLFFGMLLLGVGSGCQLCVQPVTALFREASSTAMATLSGAFQISGVVFLWLSAMSTAGAGRSGAYGFHACCVAVLFALSAAFLPSGGTFARRKKNYEPGGAGEKEGGGDDVEKNGDLAPASAASATAATTGGLTLAKIELVNRDEKRAAPRDDASDDASDASDASDAPSPSPSAPASPGRGRARRELMTSGEYILLLAWFSVIMPPMQYYIMSIGYQLERKGDDDGLYTSLFAVLYGLAAALAPPAGMIADRFGVGVGQGVATSTLAISFLILLSPSLPAQVVGMAFYSVGRLFVFAMYFSNLGRRFGFEHYGALAGTGMLCASFASLLQYPMFTAAVDGGTEGENAVNAGCAAAVAAVFPYTAWLAARERRKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPW6</accession>
    <name>C1MPW6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57066</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057657.1">
        <property type="nucleotide sequence ID" value="XM_003057611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPW6"/>
    <dbReference type="GeneID" id="9683086"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57066"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="84" mass="9346" checksum="A00C21FD66EFEB7F" modified="2009-05-26" version="1">MSKTLHLATPDMTRDGAAEVLQKHKIHHAVVQNIEGKFAGVFSSWDIARECALDAKVRPPSRPVPRDPRARLSHVFPSIPRCVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ17</accession>
    <name>C1MQ17_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SNF2 super family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_67217</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057682.1">
        <property type="nucleotide sequence ID" value="XM_003057636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ17"/>
    <dbReference type="GeneID" id="9683133"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67217"/>
    <dbReference type="OMA" id="RTNASWI"/>
    <dbReference type="OrthoDB" id="495193at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136:SF1">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin-like" evidence="3">
        <location>
            <begin position="95"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="530" mass="56793" checksum="727B69F66C3B4D82" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQD0</accession>
    <name>C1MQD0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57245</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057734.1">
        <property type="nucleotide sequence ID" value="XM_003057688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQD0"/>
    <dbReference type="GeneID" id="9683546"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57245"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="246" mass="27039" checksum="B170B946ACC5DCAF" modified="2009-05-26" version="1">MTTASRPCATLARVGGGGALVAADAFVAFEDPEVQDAVEDARAKVDLLRGVTEARLKKLSRAQLTGIVSDLLAMAARFEFEREERFERMKRETAPPPPPPRRNRSPGGAAGARARASQTPISTTTTTTTTTRRPAETTRRDREWLRVNQRAPPTRVETESAVVIQAHARGYLSRARARENRSRRAREGVDGSAGAPAAKSRTTPLTGPELVAREMARAKMEHLVNEFKERKRRDAAFLEKSARDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQV0</accession>
    <name>C1MQV0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_39409</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057818.1">
        <property type="nucleotide sequence ID" value="XM_003057772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQV0"/>
    <dbReference type="STRING" id="564608.C1MQV0"/>
    <dbReference type="GeneID" id="9683632"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39409"/>
    <dbReference type="eggNOG" id="KOG2043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WAKANQT"/>
    <dbReference type="OrthoDB" id="498698at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17731">
        <property type="entry name" value="BRCT_TopBP1_rpt2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044254">
        <property type="entry name" value="At4g02110-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059215">
        <property type="entry name" value="BRCT2_TopBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47181">
        <property type="entry name" value="BRCA1 C TERMINUS DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47181:SF2">
        <property type="entry name" value="BRCA1 C TERMINUS DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="16"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="120"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="770"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="787"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="810"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="852"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="871"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1201" mass="128217" checksum="25507A3F1662F4B8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQW1</accession>
    <name>C1MQW1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57432</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058199.1">
        <property type="nucleotide sequence ID" value="XM_003058153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQW1"/>
    <dbReference type="GeneID" id="9683637"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57432"/>
    <dbReference type="eggNOG" id="ENOG502SZNJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45013at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="157" mass="17339" checksum="43AE8FB949784967" modified="2009-05-26" version="1">MSDSDDSWDIPEEGTFARVDSEAIAAAEAKAAAEERARAKREADARKDAEAKAAEAKAREEEREERDSEPLILVDITALDPSVHNKHDKNAVNDVDKASKWRRTIEADFRKYSSDATLVANGTVRACSRGVYLPALQQLREDVPGHYWVAVFPPASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRH5</accession>
    <name>C1MRH5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_47177</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058309.1">
        <property type="nucleotide sequence ID" value="XM_003058263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRH5"/>
    <dbReference type="STRING" id="564608.C1MRH5"/>
    <dbReference type="GeneID" id="9683366"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47177"/>
    <dbReference type="OMA" id="LMFCIDG"/>
    <dbReference type="OrthoDB" id="496389at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238">
        <property type="entry name" value="MEMBRANE BOUND PREDICTED REDOX MODULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="THYLAKOID MEMBRANE PROTEIN TERC, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="302"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="315" mass="33782" checksum="2BB8039380055159" modified="2009-05-26" version="1">MSHRSFYDAFFVEVLMSVDNVCLFLRLFDWFGVPRETRPGILLAGTPILFAIRALIFFALDEVYYKIRPLMFVVGVGIACQGLLVLRHLRLARTTNDTRGDDEAVTTKDDEDEEDGGDGDGGEQIARACARVCGCESRMTTYDGSAFVTRTKRGVIALTPMLLCVGVVELFDGSFCVDSVSTVFELEHHHVLTLYLGDVVAACMMRALYPQLAGTVDVFPDLNYSVSAVLVMVGVDMCMGVFGRDIPSVTAACAMAGAFACGICSSVIRGKTCGDVRNIFMRGPCPRPGGGFGGDHNDRGGTRSGGYGSLVAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS26</accession>
    <name>C1MS26_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68349</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058613.1">
        <property type="nucleotide sequence ID" value="XM_003058567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS26"/>
    <dbReference type="GeneID" id="9684052"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68349"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="401" mass="43609" checksum="3D325054D4F09D28" modified="2009-05-26" version="1">MTRPSQGKRRPATPQRVKEAREQFAALSYTPKNEEEALSPSKLDGWEGNASHDPKNAGVKVDLVARRRTDGIFDERHTAVGAGQPKHSKRALAGPGGTREEDEFRSSIKKIEQPPSLTGGERKWKGKAIVRRYDDPTAHQYRGHVDGDGASPHGGVFAPKYPTGGTTYAPPSGEAPAGFNPGREGAIQDGYKAADKLDETIFHPAHQRSHPGERQRDGIEKDGSMVPARRDAYNPQEGMFSETRNTFEHAGEATRSSVTSEGGAMVPARPDQGEYQAQEGIFAENRNVFEHAGKDTKSSLGYGMVPDQQRFEGDANAHLNAHRGKATKSSIRFGPTSPDSSPEQPAIAHVDGGRRKIGGQKTPDSTGAKRPEDGFYRSGFASGMTPRREAARDGKWTMRMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSA1</accession>
    <name>C1MSA1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_58407</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6 7 8">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059014.1">
        <property type="nucleotide sequence ID" value="XM_003058968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSA1"/>
    <dbReference type="STRING" id="564608.C1MSA1"/>
    <dbReference type="GeneID" id="9684086"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58407"/>
    <dbReference type="eggNOG" id="KOG0820">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANYRTWC"/>
    <dbReference type="OrthoDB" id="74991at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000007">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 8" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 7 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="9">
        <location>
            <begin position="44"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH57469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="380" mass="41756" checksum="2C7E9AB34C94978C" modified="2009-05-26" version="1">MSSGIRVAGGIAKHVKKKGAQQAAYQGIQFLKSYGQHILKNPMIVNAIVEKGGVKSTDVVLEIGPGTGNLTMRLLETAKKVIAIEFDPRMVVELERRVSGTPHGHNLKIISGDFLKVDLPYFDVCIANCPYQISSPLVFKLLSHRPMFRSATLMFQREFAMRLCVNPGDPLYCRLSVNAQLLARTTHILKVGKNNFRPPPKVDSSVVRIEPRSPMIDVNFREWDGLVRLCFGRKNKTLGGIFRAKTVLQLIENNYKTYKALQVNNGKGVSAMDMGSGGVGNVSSKMLGAATMGARKKGKFSQKGKKQYGLGADEKMDIDDGDEDGNGITSVDAVTPEFIRGLVEKVLNTDGFVDMRASKMSQDDFLRLLATFNEAGIHFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSC4</accession>
    <name>C1MSC4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58433</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058655.1">
        <property type="nucleotide sequence ID" value="XM_003058609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSC4"/>
    <dbReference type="STRING" id="564608.C1MSC4"/>
    <dbReference type="GeneID" id="9684468"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58433"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="9970274at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF3">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="207" mass="23274" checksum="22E2EF137D077B7B" modified="2009-05-26" version="1">MSFDDIPENAASVVFSHLGEDPIDRVRLAAVSKVWRSAEKAGASSPGTPRAFFDLGEGFYDEGEHEKALYWWCKAIDDRDKGSALARWSVKRCLAKAFESYKRASELGHARATYKVALCYDFGTGVEQDDAKMVEWYVKAADLGDYCAAWQLSTIYEHGWRGVAVNKKEALKWCRVAAELEPHFAKDHQDRIVHLVREVATPRTNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSF7</accession>
    <name>C1MSF7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein transport protein SEC23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MICPUCDRAFT_33721</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasmic vesicle</location>
            <location evidence="11">COPII-coated vesicle membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Endoplasmic reticulum membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the SEC23/SEC24 family. SEC23 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059046.1">
        <property type="nucleotide sequence ID" value="XM_003059000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSF7"/>
    <dbReference type="STRING" id="564608.C1MSF7"/>
    <dbReference type="GeneID" id="9684110"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33721"/>
    <dbReference type="eggNOG" id="KOG1986">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WKMETED"/>
    <dbReference type="OrthoDB" id="10256289at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11287">
        <property type="entry name" value="Sec23_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.730:FF:000005">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.380:FF:000001">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000014">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037364">
        <property type="entry name" value="Sec23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037550">
        <property type="entry name" value="Sec23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141:SF0">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <keyword evidence="5 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="14">
        <location>
            <begin position="56"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="15">
        <location>
            <begin position="123"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="17">
        <location>
            <begin position="429"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="16">
        <location>
            <begin position="560"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="13">
        <location>
            <begin position="677"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH57501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="809" mass="87658" checksum="07A2910240685F09" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSN2</accession>
    <name>C1MSN2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_17472</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058705.1">
        <property type="nucleotide sequence ID" value="XM_003058659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSN2"/>
    <dbReference type="STRING" id="564608.C1MSN2"/>
    <dbReference type="GeneID" id="9683803"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17472"/>
    <dbReference type="eggNOG" id="KOG2961">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CDANEMI"/>
    <dbReference type="OrthoDB" id="198652at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027706">
        <property type="entry name" value="PGP_Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010021">
        <property type="entry name" value="PGPP1/Gep4"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01668">
        <property type="entry name" value="YqeG_hyp_ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF25">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROPHOSPHATASE GEP4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09419">
        <property type="entry name" value="PGP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="176" mass="19515" checksum="64970E146D227803" modified="2009-05-26" version="1">MALGAKRDLAMPHLEVPDVRWIDWDALHAAGFRAIVFDKDNTLTIPYERRIHPPLASALRECKRAFGAANVAVLSNSAGLTQARSDSHWSPYDRVRDALGVGFLRHSSKKPGGSCDALVRRFACEPSQMVMIGDRYMTDVVYGNRHGMLTIRCAPFTDAVRDCSPYDPVRDVNAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSY7</accession>
    <name>C1MSY7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_57873</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058764.1">
        <property type="nucleotide sequence ID" value="XM_003058718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSY7"/>
    <dbReference type="STRING" id="564608.C1MSY7"/>
    <dbReference type="GeneID" id="9683826"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57873"/>
    <dbReference type="eggNOG" id="KOG1174">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MGECYYY"/>
    <dbReference type="OrthoDB" id="308440at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF36">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="453"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="86"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="628" mass="65533" checksum="E3132B1B3719F861" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTN2</accession>
    <name>C1MTN2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Large ribosomal subunit protein bL31c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">50S ribosomal protein L31, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_58133</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058889.1">
        <property type="nucleotide sequence ID" value="XM_003058843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTN2"/>
    <dbReference type="GeneID" id="9684328"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58133"/>
    <dbReference type="OMA" id="MPRKGIH"/>
    <dbReference type="OrthoDB" id="1840965at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="entry name" value="Ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_bL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_bL31_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="83" mass="9380" checksum="2DE20E713E4DD741" modified="2009-05-26" version="1">MPRKGIHPLLYRISIVGTKGATFPWLSAVPFKAGKFFCQTDQDTHVLWTGKKEVKAATGQVAKFKRRFDYLSEAELPGGNKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTP8</accession>
    <name>C1MTP8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_17808</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059357.1">
        <property type="nucleotide sequence ID" value="XM_003059311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTP8"/>
    <dbReference type="STRING" id="564608.C1MTP8"/>
    <dbReference type="GeneID" id="9684797"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17808"/>
    <dbReference type="eggNOG" id="KOG2708">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KRAMAHC"/>
    <dbReference type="OrthoDB" id="10254073at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000105">
        <property type="entry name" value="Probable tRNA N6-adenosine threonylcarbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF14">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gcp-like" evidence="1">
        <location>
            <begin position="20"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="184" mass="20269" checksum="1FA561F6791BC50F" modified="2009-05-26" version="1">MGANRCGSPAPPSNALLVASIEQEAKKGTKFIDLPYAVKGMDVSLSGVLTFAEKEARRVFLTLRMRRGECTAADLCFSLQETIFAMLVEITERTMAHCNTQDVLIVGGVGCNVRLQEMMGEMVKQRGGALYATDDRYCVDNGAMIAYAGLLAFMEGDVTAMKDTTCTQRYRTDDVLVTWRKDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTT3</accession>
    <name>C1MTT3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Set domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58542</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059373.1">
        <property type="nucleotide sequence ID" value="XM_003059327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTT3"/>
    <dbReference type="STRING" id="564608.C1MTT3"/>
    <dbReference type="GeneID" id="9684813"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58542"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WMEVNER"/>
    <dbReference type="OrthoDB" id="513752at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="1"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="740" mass="78303" checksum="474682A78409B4F4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU10</accession>
    <name>C1MU10_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_58628</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS54 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059414.1">
        <property type="nucleotide sequence ID" value="XM_003059368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU10"/>
    <dbReference type="STRING" id="564608.C1MU10"/>
    <dbReference type="GeneID" id="9684566"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58628"/>
    <dbReference type="eggNOG" id="KOG2115">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10259024at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039745">
        <property type="entry name" value="Vps54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012501">
        <property type="entry name" value="Vps54_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07928">
        <property type="entry name" value="Vps54"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 C-terminal" evidence="8">
        <location>
            <begin position="205"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 C-terminal" evidence="8">
        <location>
            <begin position="271"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="521" mass="53062" checksum="5AB31C658A0CB900" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU77</accession>
    <name>C1MU77_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_10111</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059447.1">
        <property type="nucleotide sequence ID" value="XM_003059401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU77"/>
    <dbReference type="GeneID" id="9684887"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_10111"/>
    <dbReference type="eggNOG" id="KOG4150">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LHEGVQY"/>
    <dbReference type="OrthoDB" id="18781at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17923">
        <property type="entry name" value="DEXHc_Hrq1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18797">
        <property type="entry name" value="SF2_C_Hrq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957:SF3">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="MZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="16"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="257"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="711" mass="76566" checksum="D715702803C9A13C" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU95</accession>
    <name>C1MU95_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">acetate--CoA ligase</fullName>
            <ecNumber evidence="1">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_58717</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059156.1">
        <property type="nucleotide sequence ID" value="XM_003059110.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MU95"/>
    <dbReference type="GeneID" id="9684898"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58717"/>
    <dbReference type="eggNOG" id="KOG1175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HYTVEMI"/>
    <dbReference type="OrthoDB" id="203851at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1108"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="41"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="870"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1036"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1074"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1396"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="885"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="903"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1423"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1448"/>
            <end position="1457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1457" mass="155525" checksum="3ED5990E11ECABC8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUA9</accession>
    <name>C1MUA9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA sliding clamp PCNA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_33859</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PCNA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059464.1">
        <property type="nucleotide sequence ID" value="XM_003059418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUA9"/>
    <dbReference type="STRING" id="564608.C1MUA9"/>
    <dbReference type="GeneID" id="9684604"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33859"/>
    <dbReference type="eggNOG" id="KOG1636">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EMKLINM"/>
    <dbReference type="OrthoDB" id="534348at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043626">
        <property type="term" value="C:PCNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019985">
        <property type="term" value="P:translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.70.10.10:FF:000001">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022659">
        <property type="entry name" value="Pr_cel_nuc_antig_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01251">
        <property type="entry name" value="PCNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00293">
        <property type="entry name" value="PCNA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA C-terminal" evidence="9">
        <location>
            <begin position="127"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="263" mass="29215" checksum="9D381FC62C5E4F9E" modified="2009-05-26" version="1">MFEARLVQGSLLKKVLESIKDLVTDANFDCSQNGFALQAMDSSHVSLVALLLRNDGFEHYRCDRPMTMGMNLTNMSKMLKCAGNDDIITMKADDAGDVVTFMFESPEQDKISDFELKLMDIDSEHLGIPDTEYAATVKMPSAEFQRICRDLSSIGDTVTISVSKDGVKFSTTGDIGQANITCRQNTSVDKEEQTVIELQEPVTLTFALRYLNSFTKATPLAPTVQLQMSKELPVVVQYLIADMGYVRYYLAPKIEDEETAGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUL1</accession>
    <name>C1MUL1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biogenesis of lysosome-related organelles complex 1 subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58849</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BLOC1S1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059216.1">
        <property type="nucleotide sequence ID" value="XM_003059170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUL1"/>
    <dbReference type="STRING" id="564608.C1MUL1"/>
    <dbReference type="GeneID" id="9684656"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58849"/>
    <dbReference type="eggNOG" id="KOG3390">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THAMNSA"/>
    <dbReference type="OrthoDB" id="20018at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031083">
        <property type="term" value="C:BLOC-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009395">
        <property type="entry name" value="BLOC1S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13073:SF0">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13073">
        <property type="entry name" value="BLOC-1 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06320">
        <property type="entry name" value="GCN5L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="102" mass="11530" checksum="E967E0AB79F7C117" modified="2009-05-26" version="1">MNDALADAVSGDVHDVFEAQKKIEERSRELREKSVRFASVTGEWTRFLNNFDDALRGIGDFERWVKEVEFDLNNLTGVMKYVEEGAEEERGGADAGDEDGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUT3</accession>
    <name>C1MUT3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_58925</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059248.1">
        <property type="nucleotide sequence ID" value="XM_003059202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUT3"/>
    <dbReference type="STRING" id="564608.C1MUT3"/>
    <dbReference type="GeneID" id="9684994"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58925"/>
    <dbReference type="eggNOG" id="KOG2257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="690928at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052263">
        <property type="entry name" value="GPI_Anchor_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013717">
        <property type="entry name" value="PIG-P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08510">
        <property type="entry name" value="PIG-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PIG-P" evidence="7">
        <location>
            <begin position="27"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="105"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="232" mass="24225" checksum="F33AD31B82B5D066" modified="2009-05-26" version="1">MGRSAAVATSPPASEHPHASSQGASPTEAYGFVGFILSGVAFALYLLWAYVPDDALRALGVACSPDKYWAVALPTWAGVALVYAAVAYESLCMLDVKRPEDVDGMEELSDAGAIPRRSRGDDPEVRARRGASRARVGTPPYRFSSRLVSRRPRVVASSHRDISPRPRLDSSLAPPGSRARDQGPASVRGVPGVISRARGAAARAAASGGGTSVTASSQSRSALGWAAGRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW28</accession>
    <name>C1MW28_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59602</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059852.1">
        <property type="nucleotide sequence ID" value="XM_003059806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW28"/>
    <dbReference type="GeneID" id="9685581"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59602"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="359" mass="39740" checksum="8EC8FDD387138908" modified="2009-05-26" version="1">MSSGGARRLLRAGARAACNARAPRSIERWRAASGARAWGLETSRGADEWEDARLRFGGRWKRSIGASERHRRWTSSSSSTTTTTTPGEDGADAAVDKPTAGGYEYVNARGKMQPTSETRPSPSPSSDAAAEKDAAATTTTTTAREAPADAAENAYREILGITSLFTGPNSAWSVAFKRRPGFEPSALARREANQYRRVITPRVLRPSPPLACKYLDGPAWSCGPCPAARERPETTEVPADGEFRRAGDVTSCNYARRATESACVSNQIIFFRFFYSTTWVASWIILTQYVVSPLLGPLLPLVSGTPWIRFWICFFAAYKLNKHHALQMPRLMFAMHATRQTGWLVGELVGNFRRRRRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWS5</accession>
    <name>C1MWS5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_71053</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059679.1">
        <property type="nucleotide sequence ID" value="XM_003059633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWS5"/>
    <dbReference type="STRING" id="564608.C1MWS5"/>
    <dbReference type="GeneID" id="9685415"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_71053"/>
    <dbReference type="eggNOG" id="KOG0539">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WTIVEYF"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080132">
        <property type="term" value="F:fatty acid 2-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014430">
        <property type="entry name" value="Scs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863:SF1">
        <property type="entry name" value="FATTY ACID 2-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863">
        <property type="entry name" value="FATTY ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="10">
        <location>
            <begin position="6"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="101"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH55631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="459" mass="48499" checksum="5B1194FED9918070" modified="2009-05-26" version="1">MAPSPPRSYTRQDVRDGVRVVKGVRAGVGASLIVVDGGVYDVGGFAHPGGERSLRAFVGGARDASSAFRGDGGRSSVRAHAHSDAARRILARLKVGVLVEDDDVDDDDDDDDDDDAATASEDSDDAAASEDGSTTTTTIDAHGVDLSKPLVAQVGALGDAYESWTREPLLGSGPMRFFKSDVLERASRTRWWVVPTVWLPVAFAAFARGVLGVVAATERGRVGGDDSSDSIAAIAGAGDRDDSDAVAARVVVVVVVVVVVATFFAIGAAAWSVGEYVFHRFVFHRAPRTRAGIVAHFLMHGCHHKSPMDALRLVFPPAPWAAVVAASWLAWTRALAPTPATGAIAFAGCLTAYVHYDCVHYFLHHDATIGAIGEREGGEGGGGGGGRSGWRWGPARGWIRRALIGERGGKSELRSTHMKHHYDDCDVSFGITNRVLDRILGTTPNGDAMKGARAKARVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXI0</accession>
    <name>C1MXI0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 31 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_34641</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060696.1">
        <property type="nucleotide sequence ID" value="XM_003060650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXI0"/>
    <dbReference type="SMR" id="C1MXI0"/>
    <dbReference type="STRING" id="564608.C1MXI0"/>
    <dbReference type="GeneID" id="9685838"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34641"/>
    <dbReference type="eggNOG" id="KOG1065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10070917at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06592">
        <property type="entry name" value="GH31_NET37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050985">
        <property type="entry name" value="Alpha-glycosidase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053">
        <property type="entry name" value="GLYCOSIDASE FAMILY 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053:SF4">
        <property type="entry name" value="MYOGENESIS-REGULATING GLYCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="5">
        <location>
            <begin position="149"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="6">
        <location>
            <begin position="462"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="561" mass="62292" checksum="E2C46B6D7B9BF420" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXT0</accession>
    <name>C1MXT0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Flagellar outer dynein arm intermediate chain 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ODA-IC2</name>
        <name evidence="13" type="ORF">MICPUCDRAFT_49656</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein intermediate chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060449.1">
        <property type="nucleotide sequence ID" value="XM_003060403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXT0"/>
    <dbReference type="STRING" id="564608.C1MXT0"/>
    <dbReference type="GeneID" id="9686184"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49656"/>
    <dbReference type="eggNOG" id="KOG1587">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WDFFYRQ"/>
    <dbReference type="OrthoDB" id="366230at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF7">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="497"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH55218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="566" mass="64420" checksum="CE52AFEEDEC1CB62" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ24</accession>
    <name>C1MZ24_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60577</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060883.1">
        <property type="nucleotide sequence ID" value="XM_003060837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ24"/>
    <dbReference type="GeneID" id="9686322"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60577"/>
    <dbReference type="OMA" id="TETHFAW"/>
    <dbReference type="OrthoDB" id="10611411at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="556" mass="56110" checksum="B78FD4CBE8A8AB37" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ28</accession>
    <name>C1MZ28_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60581</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061142.1">
        <property type="nucleotide sequence ID" value="XM_003061096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ28"/>
    <dbReference type="GeneID" id="9686325"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60581"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035770">
        <property type="term" value="C:ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901259">
        <property type="term" value="P:chloroplast rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000963">
        <property type="term" value="P:mitochondrial RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044528">
        <property type="term" value="P:regulation of mitochondrial mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050870">
        <property type="entry name" value="FAST_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228">
        <property type="entry name" value="FAST LEU-RICH DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228:SF40">
        <property type="entry name" value="LD45607P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="717" mass="73756" checksum="F44AB44A717ECE9B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZK5</accession>
    <name>C1MZK5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_60763</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060969.1">
        <property type="nucleotide sequence ID" value="XM_003060923.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9686675"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60763"/>
    <dbReference type="OMA" id="VYIDTHP"/>
    <dbReference type="OrthoDB" id="10682583at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00603">
        <property type="entry name" value="IPT_PCSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910708" evidence="2">
        <location>
            <begin position="27"/>
            <end position="2303"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="3">
        <location>
            <begin position="650"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="3">
        <location>
            <begin position="1311"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="3">
        <location>
            <begin position="1607"/>
            <end position="1673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="762"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1721"/>
            <end position="1742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="763"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="776"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2303" mass="227426" checksum="35620F49B7C327DC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZT4</accession>
    <name>C1MZT4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_41378</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061275.1">
        <property type="nucleotide sequence ID" value="XM_003061229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZT4"/>
    <dbReference type="STRING" id="564608.C1MZT4"/>
    <dbReference type="GeneID" id="9686714"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41378"/>
    <dbReference type="eggNOG" id="ENOG502SE30">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RWGSITT"/>
    <dbReference type="OrthoDB" id="2017365at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001510">
        <property type="entry name" value="Znf_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00645">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01336">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50064">
        <property type="entry name" value="ZF_PARP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PARP-type" evidence="7">
        <location>
            <begin position="5"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="97"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="207"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="235" mass="25281" checksum="BFB474B25FEABCD6" modified="2009-05-26" version="1">MSNKYVIEHAKSGRSNCRKCKDPIAKDALRWGSITTRDEHDQTYWSHLGCVTEKQFTNALESYESLREIPGVGDDEDILGQVDQAYAATQTSANFDAAQKAQEKADKGSHKVEEKEAKAAEKAKAKKDAAAAKQAEKDAKAKAKEEKERAKEEAKAAKAEQKAAAAAAKKDAAAAAADDDAEAEDDDDEPIAVSKKRKNASMKPAKVFREGNRKSSRKDAIAAEEADAPCSPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZU5</accession>
    <name>C1MZU5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48130</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061281.1">
        <property type="nucleotide sequence ID" value="XM_003061235.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9686453"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48130"/>
    <dbReference type="eggNOG" id="ENOG502SWUX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WSAFVLK"/>
    <dbReference type="OrthoDB" id="552790at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1337"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1359"/>
            <end position="1372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1378" mass="156928" checksum="0A10F1A8E52DE013" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZX0</accession>
    <name>C1MZX0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60881</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061292.1">
        <property type="nucleotide sequence ID" value="XM_003061246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZX0"/>
    <dbReference type="GeneID" id="9686467"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60881"/>
    <dbReference type="OrthoDB" id="497345at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="79" mass="8700" checksum="E373AE3BDBB091EA" modified="2009-05-26" version="1">MVVGSDESYFATFDAVREAYFPRTNEWIGEYPFLDRRAMPAVSARISRDAEDRAAFAERERRERAAGAGGGGYGPGPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N044</accession>
    <name>C1N044_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60964</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061063.1">
        <property type="nucleotide sequence ID" value="XM_003061017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N044"/>
    <dbReference type="GeneID" id="9686770"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60964"/>
    <dbReference type="OrthoDB" id="498371at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="222" mass="25199" checksum="5CF2D84508F8AF7F" modified="2009-05-26" version="1">MGHGVLYCLSIRNEYEVPYVVRKPSPSLGLPTSDDANGEELRRARRASHPPPPPPPPPRATMESRWDNRHIAPFDALPVVPADGPWTPPPHEFEPPRASRPPRPSTATLKVRYAAVRTAEDLRQAIVFAAREDDLHGLRWLLREFPKMPRDDPTPVERAAEHGHFETLKWLRARGWPFSPCAIGAAASEGRLEIVHWLRKDGNVWSGMSNYKQRVHPEYPNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1N079</accession>
    <name>C1N079_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_45789</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061349.1">
        <property type="nucleotide sequence ID" value="XM_003061303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N079"/>
    <dbReference type="STRING" id="564608.C1N079"/>
    <dbReference type="GeneID" id="9686519"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45789"/>
    <dbReference type="eggNOG" id="KOG0053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TTCVQGG"/>
    <dbReference type="OrthoDB" id="494483at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071269">
        <property type="term" value="P:L-homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000035">
        <property type="entry name" value="O-succinylhomoserine sulfhydrylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797">
        <property type="entry name" value="HOMOCYSTEINE/CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797:SF2">
        <property type="entry name" value="HOMOCYSTEINE_CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="432" mass="46602" checksum="95F739386755D3CE" modified="2009-05-26" version="1">MPSGPELKFETLQVHAGQMPDPATNSRAVPIYATTSYTFNDSKHGADLFGLRAFGNIYSRIMNPTNDVFEKRVAALEGGVGAVVVSSGMSAQFLAITTICQVGDNIVSTPSLYGGSYNQFKVTLPRLGINVKFAKDDEPASFEALAIYVETIGNPRFSVPDFRALKAVAKKHGIPVICDNTFGACGYVCQPLRHGADIVVESATKWIGGHGTTVGGVIVDGGTMDWNNGKHPVFTEPSPGYHGLRFWDTFGPTGVLGVNVAFIMRCRVEGLRDVGMCQSPHGSFNFILGLETLSLRMERHCANTLALAKFLEAHPMVTWVSYPGMSDHPYHRRAVEYFRADSFGAVLTFGVKGGLEQGRKFIDAVKLASQLANVGDAKTLVIHPSSTTHEQLTEEEQTASGVTSDMIRVSVGIEHIDDICADFAQALDVAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0E1</accession>
    <name>C1N0E1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">oligopeptidase A</fullName>
            <ecNumber evidence="8">3.4.24.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_35196</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-|-Gly-Pro-Ala is cleaved, but not Z-(Gly)(5).</text>
            <dbReference type="EC" id="3.4.24.70"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.70" evidence="8"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061619.1">
        <property type="nucleotide sequence ID" value="XM_003061573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0E1"/>
    <dbReference type="MEROPS" id="M03.A01"/>
    <dbReference type="GeneID" id="9687058"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35196"/>
    <dbReference type="eggNOG" id="KOG2089">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QPLEGPW"/>
    <dbReference type="OrthoDB" id="534666at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000009">
        <property type="entry name" value="Oligopeptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="entry name" value="Endopeptidase. Chain P, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045666">
        <property type="entry name" value="OpdA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF83">
        <property type="entry name" value="LD37516P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19310">
        <property type="entry name" value="TOP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Oligopeptidase A N-terminal" evidence="12">
        <location>
            <begin position="56"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="11">
        <location>
            <begin position="267"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH54249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="734" mass="79803" checksum="84FBD0B3AA6AE544" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0T7</accession>
    <name>C1N0T7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_62925</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the KTI12 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061694.1">
        <property type="nucleotide sequence ID" value="XM_003061648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0T7"/>
    <dbReference type="STRING" id="564608.C1N0T7"/>
    <dbReference type="GeneID" id="9686890"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62925"/>
    <dbReference type="eggNOG" id="KOG3062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="497371at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013641">
        <property type="entry name" value="KTI12/PSTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12435">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08433">
        <property type="entry name" value="KTI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="372" mass="39084" checksum="511146F9D745E4C1" modified="2009-05-26" version="1">MQVPKSSPPLDGTRGAMGASSRPRDHTSCLVLVCGHPASGKSRAAADIASRVAAAVPDAPAPVVVSEDSLHIARNAGYAHGHAEKNTRASLKSTVDRLLRKDGPIVIVDSGCGIKGFRYELWCIARAAGARHCVVHVDAPIDDARRWNASRRRSDDDDDEKEWGGYDARIFEDLVVRFERPDGKNRWDAPLFTLRPPTATTTTTTNSTPALDDECGEYKDATREETLTAAVAAITGRGIGGGGGDGGGASGGGGNKVLAPCQATQPGLGASALSDTNLRAEMDLGVQEVIDVIVRAEAESGGGGGGRAEYAFGEGLPALRVAAPPSLQQLRRMKRTFLKMVGGGLARTTVARLVVKKMFIEYVAQSAEGSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0W4</accession>
    <name>C1N0W4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51175</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061707.1">
        <property type="nucleotide sequence ID" value="XM_003061661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0W4"/>
    <dbReference type="GeneID" id="9686904"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51175"/>
    <dbReference type="eggNOG" id="ENOG502R1VP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FFPIIMD"/>
    <dbReference type="OrthoDB" id="1921626at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021467">
        <property type="entry name" value="DUF3119"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35550:SF2">
        <property type="entry name" value="OS05G0401200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11317">
        <property type="entry name" value="DUF3119"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="285" mass="30629" checksum="78A1B8AEFFC23A45" modified="2009-05-26" version="1">MHNLVTAPAPARVGASLKVAARSARVSSARTAAVVPVVARHRASIVSTHATEFDGVSIPEPARPPKSLRGASSASSAGARGFVGAAAGAIDVIPGDYRIGGVLLSVAMFLGPVCHLWTQFGVHGLLGGFLAFQASRVRFRFSDTDLDVVFIEPGADDATAASLDTDSSGDNKLQGGGANKWSFDSVVNWEFWFPGFPVLVYYKENQTKAEGQPHFFPIIMDGKKLYEVMLEKMPKSVNEKPPVSEWNLDTAFESTSLGRSIKENLSDEQKEQLKNTTGFPFLDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1F4</accession>
    <name>C1N1F4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51383</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061553.1">
        <property type="nucleotide sequence ID" value="XM_003061507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1F4"/>
    <dbReference type="GeneID" id="9687247"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51383"/>
    <dbReference type="eggNOG" id="ENOG502SUY9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="538085at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="198" mass="20341" checksum="186458C7B99670B0" modified="2009-05-26" version="1">MASFAPSPHALAPPHHPHARRGASSSRASSRAMRHRAVVVAAAPSSSSSKKKNLDGGAIRARWTVDSKYGHKADALAMLGEWIHTVGVAAGLDPAKVSLHTGALGARESAIELTVDQFDGVASLDAFFAAIPHASHRAWGSRFAEHVVDGSPRWEIFRTCVVSPPPPSAGAGAGASLPVAAAKVEHEIAASTDGSGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1P8</accession>
    <name>C1N1P8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51686</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062154.1">
        <property type="nucleotide sequence ID" value="XM_003062108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1P8"/>
    <dbReference type="STRING" id="564608.C1N1P8"/>
    <dbReference type="GeneID" id="9687393"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51686"/>
    <dbReference type="eggNOG" id="ENOG502QQRP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MEFANIH"/>
    <dbReference type="OrthoDB" id="407127at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35759">
        <property type="entry name" value="BNAA09G03860D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35759:SF1">
        <property type="entry name" value="OS07G0673000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="342" mass="35965" checksum="C6F9FF95A8DE9823" modified="2009-05-26" version="1">MASSLARAPSRPSLARAASRATAGPRAAVPRAPASPSPSPSPSPSPSAPRRSVRVGATDAGATDDATGEAWVPARREALASDVVRAMFERDAALEPRLRRIPLPPSRVPRSLTRMLMTNAASGEGGRASSSGSGSGNPFRDATHPRRLRVPDYENALADGCELTPTPRADGARRMRCGAANAYVAELFRRAARCSDDDGDGDGAAAARLSRYDLFHAHVFVRASGGRGGVVGLLMHALEYPRYDDADFPFALGNCQRGSDVAFAPAAAAGRNILWTADAAGRCAFARLDTSETSPLRGLLTVPALHTTYEGDFGDAVLGDLLYFNGVADGRKPKHSVFAFPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1S8</accession>
    <name>C1N1S8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_69996</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061965.1">
        <property type="nucleotide sequence ID" value="XM_003061919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1S8"/>
    <dbReference type="STRING" id="564608.C1N1S8"/>
    <dbReference type="GeneID" id="9687405"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69996"/>
    <dbReference type="eggNOG" id="KOG2045">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041385">
        <property type="entry name" value="SH3_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047007">
        <property type="entry name" value="XRN1_D1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041106">
        <property type="entry name" value="XRN1_D2_D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047008">
        <property type="entry name" value="XRN1_SH3_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18129">
        <property type="entry name" value="SH3_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18334">
        <property type="entry name" value="XRN1_D2_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease Xrn1 D2/D3" evidence="3">
        <location>
            <begin position="80"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 SH3-like" evidence="2">
        <location>
            <begin position="331"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="606"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="724"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="627"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="724"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="736"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="753"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="762" mass="76485" checksum="9B47375F6F84C9A5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N231</accession>
    <name>C1N231_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translocation protein SEC62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_51830</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC62 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062222.1">
        <property type="nucleotide sequence ID" value="XM_003062176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N231"/>
    <dbReference type="STRING" id="564608.C1N231"/>
    <dbReference type="GeneID" id="9687458"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51830"/>
    <dbReference type="eggNOG" id="KOG2927">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EQYNNTE"/>
    <dbReference type="OrthoDB" id="200187at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004728">
        <property type="entry name" value="Sec62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443:SF9">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03839">
        <property type="entry name" value="Sec62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="198"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="369"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH53934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="405" mass="42540" checksum="0EF1109C830D45A3" modified="2009-05-26" version="1">MSSSKASKKAAAAAAAKSGGEPSAASDPIRALAYVLRGNKGPESRSARLQDPRMGDSRVDYFRGKDLFRALRASPEILDEYAPLITGAPTPTVPTAKDRDAQVHAIATQMMKSGYFVRADRVYKTPRPGRTKRVKFPKFLEPVPSASQAFARDGEGFYAWKYDRPMSWTFVCVSFAAAVAVVLMCLFPLSPIWFKKTILYACIGILSTFFVIFSARAMVFALVWIVAGRQFWVLPNISSDEIPLDEIFSPLWAFDDVDANGAVVGYVPLVNRLMGAGSVAAVLYALYWVAPENGSAIKSISKAHGSILDLFDLNDAPKSVAGAVFNATGNETATAGGNDDVNASFGVNATVIVGEDAIEDVDATVAGGGGGDASAAAGEAEAGGGGAGGTAVPSDASRAESKAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N247</accession>
    <name>C1N247_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_51846</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANT/ATPSC lysine N-methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062027.1">
        <property type="nucleotide sequence ID" value="XM_003061981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N247"/>
    <dbReference type="STRING" id="564608.C1N247"/>
    <dbReference type="GeneID" id="9687668"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51846"/>
    <dbReference type="eggNOG" id="ENOG502S237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RPEWCES"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905706">
        <property type="term" value="P:regulation of mitochondrial ATP synthesis coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610:SF11">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="6">
        <location>
            <begin position="36"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="255" mass="27359" checksum="B47D9CE02F1E8A9E" modified="2009-05-26" version="1">MPPGGADYLGPISATPMKMVTEMLAFAGPLSSSDVVYDLGCNDGRVLVEAARAHGCAGVGVEIDARAVAKARQMAKDAGVDALVKIVRGNAVKAAIRDATVVFVYLLPAGNRKIARKLMRELAPGAIVMTYVFKLPEAWWGPWLVASEAAASTRARAAGGVDASAYNKLFKYVVPETKPAWCREGEEEGEEGEEEARRGWAGRIRTRIKILVARLVPIRPRSRGERRFLRTFFSRAAAAGVVAAAAVAAIRPARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N269</accession>
    <name>C1N269_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_51868</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062039.1">
        <property type="nucleotide sequence ID" value="XM_003061993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N269"/>
    <dbReference type="STRING" id="564608.C1N269"/>
    <dbReference type="GeneID" id="9687678"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51868"/>
    <dbReference type="eggNOG" id="ENOG502S1IB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KKTAPPC"/>
    <dbReference type="OrthoDB" id="524655at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="119" mass="12037" checksum="2C5B5EB81C613144" modified="2009-05-26" version="1">MAHTGAGPAAKQAAAKAAAKALGGVGVTLGVAFGGLTALTALATAASRAVVVARKRSAGHVCPRCDGRKYHECSTCRGKRAIEWQPLKGPTMRRLCVCPTCGGKTGLQKCLNCVGQGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2D3</accession>
    <name>C1N2D3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51486</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061854.1">
        <property type="nucleotide sequence ID" value="XM_003061808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2D3"/>
    <dbReference type="GeneID" id="9687506"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51486"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="169" mass="18035" checksum="2F7FF759E64CD487" modified="2009-05-26" version="1">MRWMFIGQIGRTLKAETGETGERRTGESRGAGREKKNSPWPAAAAAAAPPPGLLLLPPPSTERRSPVAAPLPPLLPHPNPLWCREPCATPPLPTLLSPGAWWTPPPPALRAGGSIGPVIPRVYAVLIASTSSLDSSAGWTEGVGYVGGLGFRFRVSRGRRELEDARRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2Q5</accession>
    <name>C1N2Q5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Amino Acid/Auxin permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_51622</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061916.1">
        <property type="nucleotide sequence ID" value="XM_003061870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2Q5"/>
    <dbReference type="STRING" id="564608.C1N2Q5"/>
    <dbReference type="GeneID" id="9687356"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51622"/>
    <dbReference type="eggNOG" id="KOG1305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PRMKPKQ"/>
    <dbReference type="OrthoDB" id="28208at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF458">
        <property type="entry name" value="SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="406"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="11">
        <location>
            <begin position="89"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="744"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="848"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1082"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="811"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="990"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="744"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="776"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="897"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="930"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="954"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="965"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1082"/>
            <end position="1093"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH53628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1107" mass="113684" checksum="7D79E932A38BEDD2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2S7</accession>
    <name>C1N2S7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51642</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062136.1">
        <property type="nucleotide sequence ID" value="XM_003062090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2S7"/>
    <dbReference type="STRING" id="564608.C1N2S7"/>
    <dbReference type="GeneID" id="9687369"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51642"/>
    <dbReference type="eggNOG" id="ENOG502RRFN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VHFQRMR"/>
    <dbReference type="OrthoDB" id="10598538at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027951">
        <property type="entry name" value="Nepro_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14780">
        <property type="entry name" value="NEPRO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolus and neural progenitor protein-like N-terminal" evidence="2">
        <location>
            <begin position="57"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="463" mass="48495" checksum="EE8BB806A8C6C8E4" modified="2009-05-26" version="1">MAGTAPPLPPLPPELRTAVPARSLPDGALASMRRALDALGGGGDENDPSTSAPSLVTALQCDELRRETALWERVMYKSASQHRRAVHFQRMRGLTRHLRAIASLDVGAAAAALRDGLHAGVSERARETALSTPAVRAGAHAMWKLPPRALWEDLARRFRAVARVVADADDAALACAEALSGQTAHSYFVPFALVSVAAVARVRTSLHQLAVDVVASYNALRPLLSDGAMPPPGLGESWWDDAKAPESLKCEWVSVAGASKAVRPNVRAVDGGESSAVGVIDDEDWSWRLMHGLAEGERAERNESNAAVGTATREDLGAAVPRKVRGLEVSIDVDRRDDADDAAAGKAMDAKPLYSTVSGGLGLGVAVERKPEALEVVPASIESLASTLAPPPETIDATTGDTPGGKKRRRPGGAGGVPEASPAAEVGVKKKKKKKKQTTEPAGEGDGKPQSAVERAMALLMGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1N429</accession>
    <name>C1N429_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_48621</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062473.1">
        <property type="nucleotide sequence ID" value="XM_003062427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N429"/>
    <dbReference type="STRING" id="564608.C1N429"/>
    <dbReference type="GeneID" id="9687913"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48621"/>
    <dbReference type="eggNOG" id="KOG0631">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MYQSHAS"/>
    <dbReference type="OrthoDB" id="498899at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF35">
        <property type="entry name" value="L-ARABINOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457">
        <property type="entry name" value="MEVALONATE KINASE/GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="4">
        <location>
            <begin position="50"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="5">
        <location>
            <begin position="381"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="505" mass="52947" checksum="DB9F596AF91A8365" modified="2009-05-26" version="1">MPMDQLLGAADGVASKPMTYDAAKAFFDARSTKTGLEGHTVLSSQWAAYVAGVVLVLFREHGVKFTRNKTVKSNKKAHDTLCAYVESDVPEGAGVASSAALEVATASALLSIAGVTLSPRELSLACQKAENVVVGSPCGVMDQMTVALGVKDELLKISCRPAEFLGTAKLPSACAVVGVDSGEKHSNKERTGPWSAGTDGRARPNLNLHTGSDYACVRVSAFMARRMLQKTYNVGAPPSEVPGAKMRDLSLDDDVDVGLLDDDLSAKPLEYLTEIPPHVWDSPAFAERLPPAGCFMEGKIFLSHFADRHGDEPHTKVHPDGRYDIAGAGAHPVYEHHRCRVFAKLALAARAIESASASSASASGGGFGFDASAAQEETDETLALMGELMYQSHAAYSRLGLGSDATDTIVRACKNVGPNRGVFGAKITGGGRGGVVAVLLRSGAAGAEALELVRREVASVTGKRPRVFEGSSDGAVKFGALDVVVLPAKKAGEDYDPGCVDPDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N440</accession>
    <name>C1N440_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52400</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062726.1">
        <property type="nucleotide sequence ID" value="XM_003062680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N440"/>
    <dbReference type="GeneID" id="9687920"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52400"/>
    <dbReference type="OrthoDB" id="10574155at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="343" mass="36951" checksum="9E6949B3DEA803E0" modified="2009-05-26" version="1">MPPHASWRAPPPPRLSSRVARRRAASIAPAPRAFFDRRAPSPSSSSSSFTLFDLEREIASAPPSTSREATSVLSLPDAVWKVTKDVPLSLRDRAACVVAAEAVQTQCDLGLDGASLVVALAVREALRRNGFDGPGTRVRSGYVSRGAIARAHAWLEIDGRVLDVCDDGLALCEAARRAKVDYGDARAMREAFGDDALLAGEYSPKSRRPLTVLDVKVPVGGVSTKTSAAGLTLTPPPSNVAGAAEAVATNEKFRRVPHTASHTTPFAWCTPFLKKDFAGALSVALCRPMKHPRHQITNQSHHFPPHHPPIKRPSDASWRRRRGGGRMRGRASCPKTSWTRTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4I9</accession>
    <name>C1N4I9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_22152</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062799.1">
        <property type="nucleotide sequence ID" value="XM_003062753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4I9"/>
    <dbReference type="STRING" id="564608.C1N4I9"/>
    <dbReference type="MEROPS" id="T01.P02"/>
    <dbReference type="GeneID" id="9688446"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22152"/>
    <dbReference type="eggNOG" id="KOG0180">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CESLWES"/>
    <dbReference type="OrthoDB" id="204949at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03759">
        <property type="entry name" value="proteasome_beta_type_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033811">
        <property type="entry name" value="Proteasome_beta_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF10">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="206" mass="22828" checksum="51FA303B203E4AD5" modified="2009-05-26" version="1" fragment="single">VSIMSYNGAAIIAMCGKNCVAIASDLRFGINQQQTTAVDMKKIYEIHPHLYVGLSGASESHWSPYDRFAFRHNLYKLREGRDMRPETFANVVSAMLYEKRFGPYYAEPVVAGLDPVTFEPFITGMDLIGAAAPTDNFVVCGNNEESLFGVCESMYKPDLEPEELFEVIAQCLLAGSGRDCLAGWGGVVHVISKDKRITRTLKGRMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4J5</accession>
    <name>C1N4J5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="4">2.3.3.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_36068</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="4"/>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063010.1">
        <property type="nucleotide sequence ID" value="XM_003062964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4J5"/>
    <dbReference type="STRING" id="564608.C1N4J5"/>
    <dbReference type="GeneID" id="9688450"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36068"/>
    <dbReference type="eggNOG" id="KOG2367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTMRMLV"/>
    <dbReference type="OrthoDB" id="2015253at2759"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010177">
        <property type="term" value="F:methylthioalkylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07940">
        <property type="entry name" value="DRE_TIM_IPMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.260:FF:000001">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000010">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01025">
        <property type="entry name" value="LeuA_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054691">
        <property type="entry name" value="LeuA/HCS_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005671">
        <property type="entry name" value="LeuA_bact_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00973">
        <property type="entry name" value="leuA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002086">
        <property type="entry name" value="PRK00915.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF9">
        <property type="entry name" value="2-ISOPROPYLMALATE SYNTHASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22617">
        <property type="entry name" value="HCS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="11">
        <location>
            <begin position="87"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="630"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH52949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="649" mass="68524" checksum="F5474FC8FBBDB864" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4R3</accession>
    <name>C1N4R3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">G2-like myb-transcription factor with a n-terminal response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_52653</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063042.1">
        <property type="nucleotide sequence ID" value="XM_003062996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4R3"/>
    <dbReference type="STRING" id="564608.C1N4R3"/>
    <dbReference type="GeneID" id="9688277"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52653"/>
    <dbReference type="eggNOG" id="KOG1601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MLKRCQY"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009736">
        <property type="term" value="P:cytokinin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17584">
        <property type="entry name" value="REC_typeB_ARR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000007">
        <property type="entry name" value="Two-component response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045279">
        <property type="entry name" value="ARR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43874">
        <property type="entry name" value="TWO-COMPONENT RESPONSE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43874:SF7">
        <property type="entry name" value="TWO-COMPONENT RESPONSE REGULATOR ARR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="16"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="10">
        <location>
            <begin position="241"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="133"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="392"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="480"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="482"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="7">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH52981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="544" mass="55135" checksum="3373D0284FBE3D02" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4X4</accession>
    <name>C1N4X4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_37608</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063071.1">
        <property type="nucleotide sequence ID" value="XM_003063025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4X4"/>
    <dbReference type="STRING" id="564608.C1N4X4"/>
    <dbReference type="GeneID" id="9688309"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37608"/>
    <dbReference type="eggNOG" id="KOG1654">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TYCGENT"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000010">
        <property type="entry name" value="Autophagy-related protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="9">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH53010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="132" mass="15033" checksum="D76D3D53913278C6" modified="2009-05-26" version="1">MSARSTFKQEHALDKRQAEAQRIRDKYPDRIPVIVEKAEKSDIPDLDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFVFVNNVLPPTAALMSAVYDDHRDDDGFLYIAYSGENTFGSALDLDLIALEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5C1</accession>
    <name>C1N5C1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52887</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062941.1">
        <property type="nucleotide sequence ID" value="XM_003062895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5C1"/>
    <dbReference type="STRING" id="564608.C1N5C1"/>
    <dbReference type="GeneID" id="9688586"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52887"/>
    <dbReference type="eggNOG" id="KOG2776">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SRMFYSE"/>
    <dbReference type="OrthoDB" id="5876363at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01089">
        <property type="entry name" value="PA2G4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000029">
        <property type="entry name" value="Proliferation-associated 2G4, a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004545">
        <property type="entry name" value="PA2G4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047113">
        <property type="entry name" value="PA2G4/ARX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00495">
        <property type="entry name" value="crvDNA_42K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804:SF11">
        <property type="entry name" value="PROLIFERATION-ASSOCIATED PROTEIN 2G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804">
        <property type="entry name" value="PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="2">
        <location>
            <begin position="24"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="374" mass="40423" checksum="69E4073CEE043F5E" modified="2009-05-26" version="1">MSDSDSDREEREDETLGNPAVVDKYKVAAEIANKSLAAVIAACVPGAKVVDACALGDKSIEDEAAKFYNKKGADGQKIDKGIAFPTCVSVNNQVCHNSPAPDDDAVIEEGQAVKIDLGAHVDGYVAVVAHTHVVGADDRVPAGAQADVMEAAVVASEAAIRKLRPGASTSDVAKAIETVANDYGVKIVEGVLTHSMKRFVIDGNKVVLNKPTPELKADETTIELNEVYALDIVLSTGEGKPKMQDEKETNVYKRAIEKNYKLKMQASRAVFSEISKKFPTMPFTMRAMGDVRGAKLGLSECMKHELLHEYPVLYEKPGDAVAHVKCTVLVMQNGNDRVTTFAPQVTKSEKELMDEDLKALIAEPLKKKKKKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5K2</accession>
    <name>C1N5K2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52952</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063378.1">
        <property type="nucleotide sequence ID" value="XM_003063332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5K2"/>
    <dbReference type="GeneID" id="9688817"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52952"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="343" mass="37123" checksum="76685467F1B389C8" modified="2009-05-26" version="1">MRRANLNTRRPSLWAPLPPSLRRDSTVRDERDDSFITHDSSSSSSSSSSDDDEEAVRGGVLAGDVSVRGAPRSIERITRRSISSAVPPSPAVASFFPPTPTLTLASPSTSVSIASSPQDTDSERGDDAAAPRAAREEERSPMLPRRGGETRTRKRDRKNVASWLASGLENASSDDDDDDDVTRGNDAEATRRRANREAGAPIAVRDGNGNRNRNRFADHPGNAAADPTLRARRHGHKQKRRASRRDVEGAAEKANRRETRETKRRLARRRAYAPASAALVARLAAMYFAFVVIVLADVFATAMACYVNPGAHVMNDGADATWTAFCLMALIGAPAMAAHLAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5Y7</accession>
    <name>C1N5Y7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_22508</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063240.1">
        <property type="nucleotide sequence ID" value="XM_003063194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5Y7"/>
    <dbReference type="STRING" id="564608.C1N5Y7"/>
    <dbReference type="GeneID" id="9688680"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22508"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IAANKYH"/>
    <dbReference type="OrthoDB" id="509488at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044623">
        <property type="entry name" value="HRD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45084">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45084:SF1">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="540"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="563" mass="60093" checksum="5EAEE7FC7BBEB89D" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N676</accession>
    <name>C1N676_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63891</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063286.1">
        <property type="nucleotide sequence ID" value="XM_003063240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N676"/>
    <dbReference type="GeneID" id="9688927"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63891"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="626" mass="63958" checksum="7030929B4769D71B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6A3</accession>
    <name>C1N6A3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53212</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063497.1">
        <property type="nucleotide sequence ID" value="XM_003063451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6A3"/>
    <dbReference type="GeneID" id="9688744"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53212"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="225" mass="25784" checksum="73DFC2F9D9788209" modified="2009-05-26" version="1">MPRPPRPRTPRRRHRARARVRTGREWDRAYRARTRAARRGFATKVPVKDEPLPTIEEEEMEVLEDDDDDDDDDDDDEVLKKRRSPRERGRMGTSHDDDDDEVDSKEAHVSEYLAEELEAEEDNFAVGGLTGPAHLESKAVGLRSEADGLENTATALREGYARRQRMKVTLRDGVQGLYNFKRRGSRNSFHLQVRELEERALALREKAKELDAQALALREIANGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6J0</accession>
    <name>C1N6J0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Photosystem I reaction center subunit II, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PSAD</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_36482</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center. PSAD may encode the ferredoxin-docking protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Plastid</location>
            <location evidence="1 7">Chloroplast thylakoid membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
            <orientation evidence="1 7">Stromal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PsaD family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063552.1">
        <property type="nucleotide sequence ID" value="XM_003063506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6J0"/>
    <dbReference type="STRING" id="564608.C1N6J0"/>
    <dbReference type="GeneID" id="9689191"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36482"/>
    <dbReference type="eggNOG" id="ENOG502QQIC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MAMATQP"/>
    <dbReference type="OrthoDB" id="44at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
        <property type="term" value="C:photosystem I reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1470.10">
        <property type="entry name" value="Photosystem I PsaD, reaction center subunit II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003685">
        <property type="entry name" value="PsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036579">
        <property type="entry name" value="PsaD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31982:SF5">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31982">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT II-1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02531">
        <property type="entry name" value="PsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64234">
        <property type="entry name" value="Photosystem I subunit PsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="225" mass="24111" checksum="EEC7593A2A8F0813" modified="2009-05-26" version="1">MAAISQAQCVVNVTAAAPAARSRVALRASFSGKSVAAKPAYFAAKRQSVLVRAEEKTAEKAVEKKEEAPWSPPKLNPNTPSPIFGGSTGGLLRKAQVEEFYVLTWEAPKEMIFEMPTGGAAIMRKGPNLLKLARKEQCLALLNSMRAKNKINGCVYRVFPSGEVQYLHPKDGVYPEKVNKGRVGANNNMRSIGKNANPASIKFGGKLGSDGLASDGAGFSRVFDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6R4</accession>
    <name>C1N6R4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SKP1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_36525</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of a SCF (SKP1-cullin-F-box) protein ligase complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SKP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063597.1">
        <property type="nucleotide sequence ID" value="XM_003063551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6R4"/>
    <dbReference type="STRING" id="564608.C1N6R4"/>
    <dbReference type="GeneID" id="9689038"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36525"/>
    <dbReference type="eggNOG" id="KOG1724">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PWAFERR"/>
    <dbReference type="OrthoDB" id="7827685at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009867">
        <property type="term" value="P:jasmonic acid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18322">
        <property type="entry name" value="BTB_POZ_SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000026">
        <property type="entry name" value="E3 ubiquitin ligase complex SCF subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028729">
        <property type="entry name" value="E3_ubiquit_lig_SCF_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="5">
        <location>
            <begin position="8"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="4">
        <location>
            <begin position="106"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR028729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="155" mass="17770" checksum="14E825FEF7B579F1" modified="2009-05-26" version="1">MADDENQQVTLMSSDTEKFMVDQEVAFESETIKNMIEDTGVDAPIPLPNVSSKILAKVIEYCKYHVGGKKSETSEDEQKTFDSEFVKVDQATLFELILAANYLNIKSLLDLTCMTVANMIKGKTPEEIRKTFNIRNDFTPEEEEEVRRENQWAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6X0</accession>
    <name>C1N6X0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_42964</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063804.1">
        <property type="nucleotide sequence ID" value="XM_003063758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6X0"/>
    <dbReference type="STRING" id="564608.C1N6X0"/>
    <dbReference type="GeneID" id="9689069"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42964"/>
    <dbReference type="eggNOG" id="KOG0189">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DREARWW"/>
    <dbReference type="OrthoDB" id="7869097at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46482:SF9">
        <property type="entry name" value="5'-ADENYLYLSULFATE REDUCTASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46482">
        <property type="entry name" value="5'-ADENYLYLSULFATE REDUCTASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="75"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="208" mass="22638" checksum="C4B983071C009CC4" modified="2009-05-26" version="1">MGTPVNKLHEMGYVSIGCAPCTRAVLPGQQEREGRWWWEDGAMKECGLHSGNVSAEDKARSISRRSPYDRVRVVNAAKQDAREATEEDIFVDGSVRALDRAGIDALRGEDAHAKTTLAVLYAPWCPFCQAMEGGYESAAAALGAKGVDVVKFRADGDEKEWSKECLSLASFPTVLLFPEGRAGYVKLGSERRGPESLNIFVESVVGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N731</accession>
    <name>C1N731_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_53535</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DCC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063662.1">
        <property type="nucleotide sequence ID" value="XM_003063616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N731"/>
    <dbReference type="STRING" id="564608.C1N731"/>
    <dbReference type="GeneID" id="9689103"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53535"/>
    <dbReference type="eggNOG" id="KOG0798">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ELRWDWK"/>
    <dbReference type="OrthoDB" id="5199543at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034088">
        <property type="term" value="P:maintenance of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019128">
        <property type="entry name" value="Dcc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395:SF6">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09724">
        <property type="entry name" value="Dcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="82"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="207"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="514" mass="55340" checksum="8F7BD6822375DB9A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N790</accession>
    <name>C1N790_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65910</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063856.1">
        <property type="nucleotide sequence ID" value="XM_003063810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N790"/>
    <dbReference type="GeneID" id="9689137"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65910"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="516" mass="53973" checksum="D5EFF2C7FAA998D0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7C9</accession>
    <name>C1N7C9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53643</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063877.1">
        <property type="nucleotide sequence ID" value="XM_003063831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7C9"/>
    <dbReference type="STRING" id="564608.C1N7C9"/>
    <dbReference type="GeneID" id="9689318"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53643"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689:SF1">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="262" mass="27762" checksum="1D544BD2BA7277E8" modified="2009-05-26" version="1">MPRRRAAARTPTVSSRAVVASASTAAADANAPLFPHLDLDFRARVSPAELARCVAAAAVVTAVCALASTRHPLARALLATTPRAVRVAWALATFVVALFVARWIALEAKEQARLVAAEDAADEDSAFAAVDGVGIVHYKLRAPNNDAKDETDASKRDVATVVSCVHGFGANAYSFERATAAPLADALNAVVVAHDSPGFGLTERPRDLRAYTPRANAKVCRAMLRLAEAKAEDATGSRTPLRRVHILHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7P7</accession>
    <name>C1N7P7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66169</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063945.1">
        <property type="nucleotide sequence ID" value="XM_003063899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7P7"/>
    <dbReference type="GeneID" id="9689386"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66169"/>
    <dbReference type="eggNOG" id="ENOG502SSD2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45996at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13975">
        <property type="entry name" value="gag-asp_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="475" mass="47394" checksum="9319A92ABA84A8ED" modified="2009-05-26" version="1">MLLRAAALASPRAASPRGVASPSARRVARASTRTHLIIPRAHRARGLSPLAATAGDDDDVVDVEATSAPSSSSSSSSSSTLSALDALLGTTPSDDDAPSTSRSYDDDDGAAVISAPILWMSTPGRGASQRAGDNSGGVASALTSAAGAGSVYVAITLGLPDRSTKSQRERGVKGVELDFCVDTACSTNFILPQVAYGLDMQIVGTSPAGQGATGAVSAGQEMLLGTAKLGGNGDDGVAAITGLSAGVVPVPAPGTAGILGRSFLNCFGAVAFEWGGDRERARVDFWQAFDYAEAEKEGGLESFALNELPCGLLAVGVTVNGVSMPALVDTGAPQTIINKAAAERAGVIVGGESGESGESDGDGGGMNPFSGLVKAIKKGRERAMQDRGVMVMGAGGTPERLDRVDGAGVRLKVTGGGADGVDVFCEGVLVGELAAFQAGLGLAPGAPGVILGLDALMSRPRVVMSTAPGSPKIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7U8</accession>
    <name>C1N7U8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_49072</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064154.1">
        <property type="nucleotide sequence ID" value="XM_003064108.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N7U8"/>
    <dbReference type="GeneID" id="9689595"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49072"/>
    <dbReference type="eggNOG" id="ENOG502STTE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RMNQNFE"/>
    <dbReference type="OrthoDB" id="568498at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019902">
        <property type="term" value="F:phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052270">
        <property type="entry name" value="CACF_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22028:SF9">
        <property type="entry name" value="SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22028">
        <property type="entry name" value="SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3953"/>
            <end position="3997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4010"/>
            <end position="4039"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="955"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1842"/>
            <end position="1869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3961"/>
            <end position="3970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="3971"/>
            <end position="3982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3983"/>
            <end position="3995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="4026"/>
            <end position="4039"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="4039" mass="470613" checksum="E1E25FE8DF2F4ABD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7X7</accession>
    <name>C1N7X7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bardet-biedl syndrome 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BBS1</name>
        <name evidence="4" type="ORF">MICPUCDRAFT_36840</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064168.1">
        <property type="nucleotide sequence ID" value="XM_003064122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7X7"/>
    <dbReference type="STRING" id="564608.C1N7X7"/>
    <dbReference type="GeneID" id="9689428"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36840"/>
    <dbReference type="eggNOG" id="ENOG502QS2X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HADRRHY"/>
    <dbReference type="OrthoDB" id="10259809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034464">
        <property type="term" value="C:BBSome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005113">
        <property type="term" value="F:patched binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005119">
        <property type="term" value="F:smoothened binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028784">
        <property type="entry name" value="BBS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032728">
        <property type="entry name" value="BBS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056419">
        <property type="entry name" value="GAE_BBS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20870">
        <property type="entry name" value="BARDET-BIEDL SYNDROME 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20870:SF0">
        <property type="entry name" value="BARDET-BIEDL SYNDROME 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14779">
        <property type="entry name" value="BBS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23304">
        <property type="entry name" value="GAE_BBS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bardet-Biedl syndrome 1 N-terminal" evidence="2">
        <location>
            <begin position="49"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Bardet-Biedl syndrome 1 protein GAE" evidence="3">
        <location>
            <begin position="515"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="621" mass="67835" checksum="6539E9549FCBFEA4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N800</accession>
    <name>C1N800_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_36845</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064183.1">
        <property type="nucleotide sequence ID" value="XM_003064137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N800"/>
    <dbReference type="STRING" id="564608.C1N800"/>
    <dbReference type="GeneID" id="9689436"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36845"/>
    <dbReference type="eggNOG" id="KOG2898">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANHTTVM"/>
    <dbReference type="OrthoDB" id="10051137at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07991">
        <property type="entry name" value="LPLAT_LPCAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045252">
        <property type="entry name" value="LPCAT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063:SF2">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063">
        <property type="entry name" value="PHOSPHOLIPID ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="14">
        <location>
            <begin position="134"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH51805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="343" mass="39767" checksum="00A20399562E394B" modified="2009-05-26" version="1">MRFTEGGNNAVLPRLLDASGVLEDAANAIVDDSFHRCFNYSENPAWNWNFYLFPTWVVGVIVRYFVLFPARFTVFMCSQFLFFSSFGVVHALFRGKTRAKFERKLVKMYAASYIVTWGGVIKYHGPKPNKRAGYVYVANHTSMIDYIILTQMTPFSAIAQQNKGWVGFLQNTAMDAIDCIRFNRTESKDREMVQRRLREHVRDPDRLPLLIFPEGTCVNNEYCVMFKRGAFDLGCKVVPIAIKYNKTFAETFWHSRRQSFTQHLMSLMSSWAVVADVWYMEPQEKRPGEDGIQFAERVRSMICQRAGIKPVPWDGMLKYFKPSPRMCEKRRAEIAASLVKLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N884</accession>
    <name>C1N884_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_53987</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064037.1">
        <property type="nucleotide sequence ID" value="XM_003063991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N884"/>
    <dbReference type="STRING" id="564608.C1N884"/>
    <dbReference type="GeneID" id="9689666"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53987"/>
    <dbReference type="OrthoDB" id="420187at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="357"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="412" mass="45973" checksum="7253D283163FD1FC" modified="2009-05-26" version="1">MPSRPKNVKDLIKKAKGGCAESAFELYMHFNVGTRGVKQNDAEAGSWLEKAAQLGHVTARAICGDTRDDWGQCPENIKALMFKATKQDCGASAWELAQHYELGTGGVGKSNATGEYWLSKSYELKHIPAQLAVAKNDYRAGLDMSRPTSERTNDSQAFISEIFADVAERGDANGEFWLGAVYLHGYGVERDEAKYIELCRSAAEKGDPEAQYWYGKAYHRGIDECLQADWVKHEYWVAKSAGGGYAAAVKELKKMRKVKTEVLDLIVSITGLSLSSEARVAFVFGSPPEHRAVNEFHHVALCFLHGLCGLEKNIRLAKDILKVALFRMEKGSDDVRRDVTEDAITEVKALLKQLRRCSGCGKYAYWTCKLCRGVRYCSRKCQKWHWKHGDGEPHKVHCPRVVTTISESLLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1N892</accession>
    <name>C1N892_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bardet-biedl syndrome 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46012</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064228.1">
        <property type="nucleotide sequence ID" value="XM_003064182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N892"/>
    <dbReference type="STRING" id="564608.C1N892"/>
    <dbReference type="GeneID" id="9689483"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46012"/>
    <dbReference type="eggNOG" id="KOG1129">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QMGVNSA"/>
    <dbReference type="OrthoDB" id="421121at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034464">
        <property type="term" value="C:BBSome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21341">
        <property type="entry name" value="TTC8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028796">
        <property type="entry name" value="BBS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44177">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44177:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="351"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="455"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="505" mass="56191" checksum="A5D7B3957E6727D5" modified="2009-05-26" version="1">MHHLNATRDYDACIDLCTKMLEKNPYDQQAWTRALTAKNWIDETEMEEEGVAEIMMDENATAQVARPGTSFARPNTSASRAGGGVATGLSSFNQGMRPMTRAGAPMTGFARPATAARPSTGSSRDTIETAFRGSGRPGTSRPVSSAARLTRLGTATQLSEPGGPFIDVDKLDLRKYAQKDALARALIEYIMHHDRNPKKAVELASLATVNANFKDWWWKERLGVAYYQLGMYRDAEKQFKSSLKDQPMIKTVLQLAKVYIRIDQPAAAMATYVKGAELFPGETSMLLGQARIHDALNDMHLGVPLYKEVLKWDASNVEAIACLAANHFYTDQPEIALRFYRRLLMMGVNNTELWNNLGLCCFYASQYDMTLACFERAIKMADDEEAPDVWFNVGQVAIGIGDLGLAYQALKIAVSVDSTHAESFNNLGVLELRKGNVEAGRANFEKASREAEHAFEPAYNHALLAFKTGEFQEAYERVEKALECYPEHADSVELKKQLKKHFTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8Q5</accession>
    <name>C1N8Q5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66466</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064316.1">
        <property type="nucleotide sequence ID" value="XM_003064270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8Q5"/>
    <dbReference type="GeneID" id="9689929"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66466"/>
    <dbReference type="OMA" id="PEREINW"/>
    <dbReference type="OrthoDB" id="548304at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031367">
        <property type="entry name" value="CCDC24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28601">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28601:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15669">
        <property type="entry name" value="CCDC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="463" mass="48167" checksum="06E4E5FA16430FE0" modified="2009-05-26" version="1">MGVLDSLDALDAPSTAVPADELRQVKTLLWDIVRVNVAPAEVDEVKRALGTAAVDDNAQLMEEASALATIVGEVRRDVDDGAVARRLYENPARALVEGELRLLVKSIRRTASGDLAEGSGRPPSGRPRSLAARQETEEPEREINWADIGGGGVDDPTRVVDPPKPPPRGAGVDSLLGDALGPAMDARTEKLLVATAKERAMLEYVVGGADALSIRAGTPRTPPSRPASRCHSSRPPSSAGSHTSGAGAPESDGSSSVISDPAAAVARVGADRVTIFDVDAVAAPLRELLIEERAALLDDVEYLRRCLEEEAEIGRRVRAPPPDVTELRNYGAKLRGVLENERERAAHVAKVEKMLAAAPSDGAKKLGRVGKLRSLAKTLHADVGGGGGGDDASARMRDGGDDTSARTRDGVASPEPPAAAPARALIPAPPPAPPPIGARRQPGSGGAPSRPPLGGRRIVVSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8R4</accession>
    <name>C1N8R4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66469</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064320.1">
        <property type="nucleotide sequence ID" value="XM_003064274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8R4"/>
    <dbReference type="GeneID" id="9689934"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66469"/>
    <dbReference type="eggNOG" id="ENOG502S5SR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GVGVFSH"/>
    <dbReference type="OrthoDB" id="497525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="390" mass="41440" checksum="01C7231093512A6E" modified="2009-05-26" version="1">MATAATSVALVASSTRRARRPRWTSCPTRCGASPFGGGEIPPAGGSAFGSATTKTSGSASPFGGAGSSSATDPFETGARRRPLSSVSVSSNDTARRADVDAALIQQPSFTLAGTRDRKPTNETSSPAQPSSSSSSSSTSVSYRAWDDVEVYEVPDDLRRAGSSRVEEHVTFYGLDELFPGSGLGETFNASAAFRTAIRAAMREDMFVPDPSKSDKINTAISSLGCSVMVNWKRSKSGYAALTKVFESNGVRGVTGEAFILALGGLCGTESHGSLIDITGTGRRKERHSWHQDSGLDRRTVMLGFPPSDGFDGVGVFSHAAKLSHPLRRADGDDAEGAVIQWEDFDAGELPVEVIGRPEYRPGHEVMVYCDATHVHSAPDETNRESVWRFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8T6</accession>
    <name>C1N8T6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54234</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064329.1">
        <property type="nucleotide sequence ID" value="XM_003064283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8T6"/>
    <dbReference type="GeneID" id="9689947"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54234"/>
    <dbReference type="eggNOG" id="ENOG502SDGT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RNAMVTA"/>
    <dbReference type="OrthoDB" id="497702at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="804"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="921" mass="99050" checksum="5AE260713CCDAB61" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8X0</accession>
    <name>C1N8X0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66505</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064349.1">
        <property type="nucleotide sequence ID" value="XM_003064303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8X0"/>
    <dbReference type="GeneID" id="9689790"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66505"/>
    <dbReference type="OMA" id="DHQRGPE"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="545" mass="64718" checksum="E13435741017E499" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8X7</accession>
    <name>C1N8X7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_49200</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064355.1">
        <property type="nucleotide sequence ID" value="XM_003064309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8X7"/>
    <dbReference type="GeneID" id="9689796"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49200"/>
    <dbReference type="OrthoDB" id="495350at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="135" mass="14356" checksum="C609852E5EADCED4" modified="2009-05-26" version="1">MSAAAAARTPVIVLPGSGCTPTRECNFYAWFSDALDATRYDARTTNMPDPHVCRERAWLPFIVDPSGPLRAGPGRVARECLGLSAGTAGAEWLELEARDHFFTPPFRELVELLDRSCDAADAAAAAGAGTTTDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N940</accession>
    <name>C1N940_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL22c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_30355</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064550.1">
        <property type="nucleotide sequence ID" value="XM_003064504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N940"/>
    <dbReference type="STRING" id="564608.C1N940"/>
    <dbReference type="GeneID" id="9689830"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30355"/>
    <dbReference type="eggNOG" id="KOG1711">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CNITLKM"/>
    <dbReference type="OrthoDB" id="1840754at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_uL22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_uL22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047867">
        <property type="entry name" value="Ribosomal_uL22_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_uL22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="205" mass="21954" checksum="2B168F260D8DF515" modified="2009-05-26" version="1">MSALSRANVLTVGAASANAAPATKRACVASAARVPARASVAFGDASSRRALALGASRCRAPRDAQRGGFNVVAQAISEPPTEAAPEATNDASGDESEAVCYLNGVHMSPYKVRRVLDVIRGKSYEECLIMLEFMPYRACEPVLNALFSAASNAKNNLGMNKAKLYVSETYADGAGTMKRFHPRAQGRPFPIRKRTCNITLKMKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA03</accession>
    <name>C1NA03_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_67797</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064825.1">
        <property type="nucleotide sequence ID" value="XM_003064779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA03"/>
    <dbReference type="GeneID" id="9690266"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67797"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="192" mass="21603" checksum="9FBB2379A1768937" modified="2009-05-26" version="1">MARAKRRVELGRRFRAWSSWASRSLARRWCDARETRARATAKAFAGWRGRVLPLDRERAAAVVRAAAFATWRAAATRSSRELRETLDAVRASAATDVERAMERAAAAERSSVASLEKTRDVQDALEAFERHAAARDDAKTRELDAVRAQKADAREEIARLERRLSERASEAAVRSYLHRSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA96</accession>
    <name>C1NA96_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_67868</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064756.1">
        <property type="nucleotide sequence ID" value="XM_003064710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA96"/>
    <dbReference type="GeneID" id="9690307"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67868"/>
    <dbReference type="OMA" id="KEWAKIA"/>
    <dbReference type="OrthoDB" id="1932364at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31677">
        <property type="entry name" value="AP2 DOMAIN CLASS TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31677:SF196">
        <property type="entry name" value="ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR ERF109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="101"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="248"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="505" mass="49988" checksum="5FC7D229034DC05B" modified="2009-05-26" version="1">MSSSGDVPISHLHLNGAATAGGESRSHDKGGGGGRGTVADAEGDRGGSDAIGASAQTAAGAKRKAGALVVGTGDRRSGVGAGASSNAGPGRNARRKIGKSGFRGVAFHGVSKKFRARITSNTGDGRQRALGYYETAELAARAYDVAARELGVSADLLNFPTDAETAEGVGNGGADASAPPPADPPPPRKGAGAGRPTKREGVASLELAIVGPNGESEAALVAAAVGDGGGDGGAAVVAVKEGKATATGIKGVRLKGKGSYEARIKVRGNDKRMQLGRFPDARSAMRAYDAAARRAGYCVNRVEATGDLIDTQSLAAIGVACDVLKGVKELTHEEAAKLAIGELPAVPGGVEVVATNSAAIAGGAGGGKKYATFVRVKPGIHEYLGTFDTLEESAKKLKASRPSIRGLGKEWAKIAGGAAGAKEKGGGKGTGTGGGGDDASGGGGSKKPGKKRTLGAKHGIIAEDDGVGDADHRARLVAAEEAGRFGLGGYVAAVADADLGTPRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGF7</accession>
    <name>C1MGF7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial</fullName>
            <ecNumber evidence="8">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="8">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_45127</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>succinate + ATP + CoA = succinyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterooctamer of 4 alpha and 4 beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="8"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054766.1">
        <property type="nucleotide sequence ID" value="XM_003054720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGF7"/>
    <dbReference type="STRING" id="564608.C1MGF7"/>
    <dbReference type="GeneID" id="9680590"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45127"/>
    <dbReference type="eggNOG" id="KOG1255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VIICITE"/>
    <dbReference type="OrthoDB" id="1664372at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009361">
        <property type="term" value="C:succinate-CoA ligase complex (ADP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000005">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004230">
        <property type="entry name" value="PRK05678.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117:SF2">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117">
        <property type="entry name" value="SUCCINYL-COA LIGASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA-binding" evidence="11">
        <location>
            <begin position="20"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="8 9">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="33"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="112"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00061754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH60018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="312" mass="32273" checksum="DE6C5111FBD0F58B" modified="2009-05-26" version="1">MALRRASARALDRIAPPAVFVDKDTKVLVQGFTGKNGTFHSQQAIAYGTRMVGGVTPKKGGSTHLGLPVFNTVAEAKTATGANASAIYVPPPFAAKAILEAVEAELDLVVCITEGIPQHDMIRVKQAMMTQSKTRLIGPNCPGIIKPGECKIGIMPGYIHTPGRIGVVSRSGTLTYEAVYQTTACGLGQSTVVGIGGDPFNGTNFVDCLEKFVKDDQTEGIIMIGEIGGTAEEEAAEFIKASGTTKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAGDKIAALKAAGVTVVPSPAGMGEAMHQIFKERKMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH11</accession>
    <name>C1MH11_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_30690</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055413.1">
        <property type="nucleotide sequence ID" value="XM_003055367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH11"/>
    <dbReference type="STRING" id="564608.C1MH11"/>
    <dbReference type="GeneID" id="9680793"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30690"/>
    <dbReference type="eggNOG" id="KOG0070">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IRQRHWF"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016004">
        <property type="term" value="F:phospholipase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003500">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH60665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="183" mass="20869" checksum="FBD0A6A334792A4B" modified="2009-05-26" version="1">MGLTFTKLFQRLFSKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVSEARDELHRMLNEDELRDAVLLVFANKQDLPNAMTAAEITDKLGLHSIRQRHWFIQSTCATSGEGLYEGLDWLSTNIANAGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHB5</accession>
    <name>C1MHB5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_2423</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054927.1">
        <property type="nucleotide sequence ID" value="XM_003054881.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHB5"/>
    <dbReference type="STRING" id="564608.C1MHB5"/>
    <dbReference type="GeneID" id="9680978"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2423"/>
    <dbReference type="eggNOG" id="KOG0891">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IEWMNDT"/>
    <dbReference type="OrthoDB" id="498235at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004677">
        <property type="term" value="F:DNA-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05172">
        <property type="entry name" value="PIKKc_DNA-PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037706">
        <property type="entry name" value="DNA-PK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF68">
        <property type="entry name" value="DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="2">
        <location>
            <begin position="37"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="3">
        <location>
            <begin position="413"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="445" mass="47284" checksum="4C09B7B71BE644C2" modified="2009-05-26" version="1" fragment="single">VSSSSSTLYRHGVEVPGQYDALVVPPLPNSYAQIVGFEPEVDVFASKQRPKKLIARGGDGREYAFIAKGSEDLRQDDRIQRLFRAMDALLASSPAARSKALRVRTFHVAPLSTRCGLLEFVGGTVPLLHALTSSTKRAQLHSEAHQKTDGGVSADDYLAAMARTPAPEAARALESLSRRAAAEASPGGEQRPPESPALRTTLMNAAGSPDAFLSLRRTYASSLAATSVCGWVAGVGDRHLQNILLDLTDGSLVHIDFGYAFGTATAVLPIPELVPFRATGALLGGLAPNDAKTALRGDMTAAMHALRRGSALLRGVMDVFLREPLIDWQREARQVRVKAGKRVAVAGASGLAGDEGAHVELKIAHAWAKLDLCDPAAVTLAQCAAKHEGSSHWDGMREMVVIAGGGGTQDGKACGSVEEQVERLLRLATDPLVLATSWSGWRPWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHI1</accession>
    <name>C1MHI1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61355</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055498.1">
        <property type="nucleotide sequence ID" value="XM_003055452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHI1"/>
    <dbReference type="GeneID" id="9680234"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61355"/>
    <dbReference type="eggNOG" id="ENOG502R39I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HRIMGVT"/>
    <dbReference type="OrthoDB" id="5403181at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051213">
        <property type="entry name" value="START_lipid_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308:SF56">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="1">
        <location>
            <begin position="265"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="377" mass="40552" checksum="AF7E1DE0A1A9FDBA" modified="2009-05-26" version="1">MFEHVSFSLSVLFSLPSSPLARSRPALASAPVGFLSARELESAVADAESSQGDICASVETELAHVSRVDEVERDIVTKFFGMLTSKEWKHSTTSNGTDIFKLPGERIHRIMGVTRTEASPEEVLGFFSDPQNFKKHFTILDDMFKEGSVVKIGGQGLGLDATGERLHKLGKFAALSIGGKERVGPTDPKEFAVSLLNKIRRSPGGQKIEGLIKKHAGDKGAVAALGELPSSQTSALAQTSIRAEFKDGQFKDLPGHALLHGTFRLPSIVPDRDFVWDQVAMRLPTGSVLVMGQSVNDGDEDVPECVKGHVRGAVLTSGYYVFEDGQGGSKIAFVLQADPKGSLPAWVVNLVAPKQAHNVTRLRKYLDSTVGSSVSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHI8</accession>
    <name>C1MHI8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50213</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054961.1">
        <property type="nucleotide sequence ID" value="XM_003054915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHI8"/>
    <dbReference type="STRING" id="564608.C1MHI8"/>
    <dbReference type="GeneID" id="9680207"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50213"/>
    <dbReference type="eggNOG" id="KOG2777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NACVRRW"/>
    <dbReference type="OrthoDB" id="10268011at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003726">
        <property type="term" value="F:double-stranded RNA adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008251">
        <property type="term" value="F:tRNA-specific adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006382">
        <property type="term" value="P:adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002466">
        <property type="entry name" value="A_deamin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10910:SF62">
        <property type="entry name" value="AT07585P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10910">
        <property type="entry name" value="EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02137">
        <property type="entry name" value="A_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00552">
        <property type="entry name" value="ADEAMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50141">
        <property type="entry name" value="A_DEAMIN_EDITASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A to I editase" evidence="2">
        <location>
            <begin position="79"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="408" mass="43606" checksum="E1341439D266A5EA" modified="2009-05-26" version="1">MTAGGARSAEKVGRRVSTCAFADAIARVSIAAHDAAVASLPDPERARLSSGQTVLASIVVRDGRGGGGENDRARVRVVALGAGTKFMTSSSIDSDARGVRVRDCHAEVLARRALKRFLYAQIDIARARRGTVADARSCVLERDARSNRWSIRPDVTFHMYTSSTPCGNATVKRWARGAKEVFDDALDESTPPPDAKTHEKPSFGSVHEGQLAFTYKRDPTALEDDGGEIRERGGGGGGDAAAGAAVHITGRLLSCSDKLAVWNCVGVQGALLLCENALSSPVYLASVTVGRKFNRAILRRALCCRMHRFRGTDAISAAEDGTAAEPRSRVFALNHPGTMCTAVPFDVGTYAPGEGANFDRADALVWWEGRDGGETRELIDARTGSRSFPRGDDDISGGLFARRRVTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHK7</accession>
    <name>C1MHK7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribokinase</fullName>
            <shortName evidence="9">RK</shortName>
            <ecNumber evidence="9">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_50234</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-ribose + ATP = D-ribose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="9"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054971.1">
        <property type="nucleotide sequence ID" value="XM_003054925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHK7"/>
    <dbReference type="STRING" id="564608.C1MHK7"/>
    <dbReference type="GeneID" id="9680998"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50234"/>
    <dbReference type="eggNOG" id="KOG2855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DYLCPNE"/>
    <dbReference type="OrthoDB" id="415590at2759"/>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="Ribokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584:SF166">
        <property type="entry name" value="RIBOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 9 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 9" id="KW-0630">Potassium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="1 9" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002911912" description="Ribokinase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="11">
        <location>
            <begin position="35"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="12">
        <location>
            <begin position="439"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="42"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="72"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="260"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="294"/>
            <end position="295"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH60223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="721" mass="75727" checksum="B8E920C0578BC75C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI32</accession>
    <name>C1MI32_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">beta-carotene 3-hydroxylase</fullName>
            <ecNumber evidence="4">1.14.15.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CRTR</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_38006</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sterol desaturase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.24" evidence="4"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055596.1">
        <property type="nucleotide sequence ID" value="XM_003055550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI32"/>
    <dbReference type="STRING" id="564608.C1MI32"/>
    <dbReference type="GeneID" id="9681163"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38006"/>
    <dbReference type="eggNOG" id="ENOG502QSIR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="497530at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010291">
        <property type="term" value="F:beta-carotene 3-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016119">
        <property type="term" value="P:carotene metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016123">
        <property type="term" value="P:xanthophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045019">
        <property type="entry name" value="BETA-OHASE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31899">
        <property type="entry name" value="BETA-CAROTENE 3-HYDROXYLASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31899:SF9">
        <property type="entry name" value="BETA-CAROTENE 3-HYDROXYLASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="8">
        <location>
            <begin position="188"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="414" mass="44228" checksum="280EAA9AAAD4BAC4" modified="2009-05-26" version="1">MTTATRACGAPCAARAGVAPRTRAQCAFSRETSARATGVGGWSNGARNARASAVRCVARSKPQNGGVAESAAAAGAVRAGAGKPQLTTARSAIADTNRSVNASQDDSSSNFREPSVTPIAEKKPRRKALTKGEREAQGESYEWAAWVSTCGITSIAITATYLRLLREVTDSGAFPWSELIAQVALIAGAAVGMEFYARFAHKHLWHDSWWTMPQSWRADWNRPIWLLHESHHLPREGAFEANDIFAVSNGVPAFALCAYGFVTPGVFGGLCFGAGLGITLFGIAYMYVHDGMVHKRFPTGPLGKNKYLRQIAAGHTIHHTEKFDGVPWGLFLATQELSAVPGGMEELATVLEAADRKAAREEEEARALAAMGGSVDEGCEEGDICIADQPILRVAEHIPSQNEAPACVLPPKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI63</accession>
    <name>C1MI63_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_50450</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055074.1">
        <property type="nucleotide sequence ID" value="XM_003055028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI63"/>
    <dbReference type="STRING" id="564608.C1MI63"/>
    <dbReference type="GeneID" id="9681180"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50450"/>
    <dbReference type="OMA" id="HWADLWH"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="312" mass="31941" checksum="F6FCE0032506E4B0" modified="2009-05-26" version="1">MPHPLSAHLPMAIGTAVARCGETDVTVVMPTSESDVVDVYSAMGRPDEDPHWADVWHGDVALATAMLEGGGGGGGGGGDAGSTIDVRGRSVINLGAGLGLAGVAAALAGASRVLMTDREPRALWCSLAAARANGLRGAAETLPASCGAPDGVALGPTPKALEPASPAASRCVVDAEIVDWFEPELAPTGFDVVLASDVLYTADAVDAIATLVLRLFSSRGGRAGRFVLADPPGRFPENHARFVRCMEDPGSIPGYAGEALITGASIERVDERIVECVNLVGETMAVKLSTYDITVPSRRARDGSASILSSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIC7</accession>
    <name>C1MIC7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_12843</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055105.1">
        <property type="nucleotide sequence ID" value="XM_003055059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIC7"/>
    <dbReference type="STRING" id="564608.C1MIC7"/>
    <dbReference type="GeneID" id="9680343"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12843"/>
    <dbReference type="eggNOG" id="KOG2649">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CDYHEAK"/>
    <dbReference type="OrthoDB" id="10249045at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057246">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050753">
        <property type="entry name" value="Peptidase_M14_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11532:SF57">
        <property type="entry name" value="CARBOXYPEPTIDASE D, B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11532">
        <property type="entry name" value="PROTEASE M14 CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00132">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910263" evidence="3">
        <location>
            <begin position="27"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="4">
        <location>
            <begin position="67"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="376" mass="39931" checksum="4E093052D8D0640D" modified="2009-05-26" version="1" fragment="single">MTRARRGLLVLVAVALLASATARADALETVDVARPSDGGVVGSDAVPRTKQTIAADADADPTREEWRYRTNEELAAALRALHEGACAGISALSSTGRSVRGVDLPVLEIAVPEEKANSKTGAGGDNGGAKPSFGFIANMHGDEPVGRELALRLARLLCDAHRGVGGGGGDGDDAATLTAAAALVASARLFFVPTMNPDGFATRSRNNANGVDLNRDFPDQFRGGLKLERGDFGGGGDDDDAAGRQPETAAMMRWATNLTAALNFHEGALVANYPWDGTDDGKTRYSRAPDDPAFRRMASAYASAHRGRMIPATAELSIARKSRRPNEERFKGGITNGAAWYPLWGGMQDWHYIVTGTMALTIEVNEVKWPEVRELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MII8</accession>
    <name>C1MII8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_38106</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055137.1">
        <property type="nucleotide sequence ID" value="XM_003055091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MII8"/>
    <dbReference type="STRING" id="564608.C1MII8"/>
    <dbReference type="GeneID" id="9680860"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38106"/>
    <dbReference type="eggNOG" id="KOG2405">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LMFDCRV"/>
    <dbReference type="OrthoDB" id="532819at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040:SF1">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="240"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="516" mass="53203" checksum="5E050B3826A43C98" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIJ4</accession>
    <name>C1MIJ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_38109</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055677.1">
        <property type="nucleotide sequence ID" value="XM_003055631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIJ4"/>
    <dbReference type="GeneID" id="9680543"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38109"/>
    <dbReference type="OMA" id="VVKYALM"/>
    <dbReference type="OrthoDB" id="10671211at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069">
        <property type="entry name" value="GH20023P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069:SF2">
        <property type="entry name" value="GH20023P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="58"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="469"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="247"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="500" mass="51499" checksum="0E9188ED1C6877A4" modified="2009-05-26" version="1">MSAATDWSLTRETLVRVSCVDPLPAPPEYLDDAAVERLRGWDASARDGGGPALGVNCCAVCAASFAAAPSACERCDVVKYCGEACLEKDAATHAPICALASFASRLAAVEMDAIDARAAAAASARACVKNVKLLGKTGTSHILGPRGYGERDSERIDADACASRWGAVLKLAERGNAHVVVPKSAEAATADDDARLAANAAAAKTAKTLNDFASTASYPLSVVAASWLFPVVKYALMLGVSGHRVDDDDDGGGDGGDANESESPTEPAALHVVCGPDADAHALDAPSDVWWLLGAGAALDKPGVDVSLIGEGVAANEMANEYGFAGSSHTPSVKRFAESYETHAAAAARGPCLVFGVGLNIANAWATLRGEEEEEEEEDASETTEEKLNVIGAAAGAVRAARRAGCPLLTSNPTRVDVSYEQEAMEDVFGYELVGMARNPFAYATPELAGVGDVIRRNEWLAAYVPKRSAAAEVGGEGAKRSGDDGGGGGGDAKKAKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIJ5</accession>
    <name>C1MIJ5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetratricopeptide repeat protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_46342</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055141.1">
        <property type="nucleotide sequence ID" value="XM_003055095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIJ5"/>
    <dbReference type="STRING" id="564608.C1MIJ5"/>
    <dbReference type="GeneID" id="9680863"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46342"/>
    <dbReference type="eggNOG" id="ENOG502R2C2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QLAWMSG"/>
    <dbReference type="OrthoDB" id="626167at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051476">
        <property type="entry name" value="Bac_ResReg_Asp_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46630">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46630:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="459" mass="48771" checksum="1BFFC91EB19A8063" modified="2009-05-26" version="1">MDTETILMNHRPPEEPDKQTMSIEALMEGCPAAFIDFYYLTTAGDGVADDQPSAAQVAARLAAGQAADALDAKKIEEFIDDEVDPEHMPFVRDALVHAESSAREGDDAGTQDAFRSIAEFFLKVGDPRKGIFFYEKRLKAARKAKDPAAEMVADGDLGRVYESMGDIPHAIAAYERLVAVAAADGSRDDVSSSRRHLIRAYNAAADAKTREGDGDGAVRFLTSALDVARKEGESDGGVLLEADANYRLGLALARIGEHAAALERQDDHLTLCARKASPVDAVGAGKARRALAASRLAMRDAAIASGETAAAEAHQREAARCLEFFLDGEPPDNGGGGGGGMSAILLAKAREAETEEESGGKGVVRDPGADARAWCTLGKIRSAEGEHAKAASCFEKFFELARGLSDQRLLDVARINLGIARGKVKQEKFMSTVLHAGEDGTKEGSEALGNLLSWKVARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIL7</accession>
    <name>C1MIL7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginyltransferase</fullName>
            <ecNumber evidence="2">2.3.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_46353</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the R-transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.8" evidence="2"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055152.1">
        <property type="nucleotide sequence ID" value="XM_003055106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIL7"/>
    <dbReference type="STRING" id="564608.C1MIL7"/>
    <dbReference type="GeneID" id="9681099"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46353"/>
    <dbReference type="eggNOG" id="KOG1193">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SDRMVYS"/>
    <dbReference type="OrthoDB" id="74183at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004057">
        <property type="term" value="F:arginyl-tRNA--protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007472">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007471">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="ARGININE-TRNA-PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367:SF1">
        <property type="entry name" value="ARGINYL-TRNA--PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04377">
        <property type="entry name" value="ATE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04376">
        <property type="entry name" value="ATE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-end aminoacyl transferase N-terminal" evidence="6">
        <location>
            <begin position="33"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="N-end rule aminoacyl transferase C-terminal" evidence="7">
        <location>
            <begin position="297"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="529"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="641"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="545"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="645"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="664" mass="69917" checksum="289D4096BD96BDE1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIV6</accession>
    <name>C1MIV6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_2596</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055730.1">
        <property type="nucleotide sequence ID" value="XM_003055684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIV6"/>
    <dbReference type="STRING" id="564608.C1MIV6"/>
    <dbReference type="GeneID" id="9680312"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2596"/>
    <dbReference type="eggNOG" id="KOG0411">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DLCFAME"/>
    <dbReference type="OrthoDB" id="15270at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032216">
        <property type="term" value="F:glucosaminyl-phosphatidylinositol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009447">
        <property type="entry name" value="PIGW/GWT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06423">
        <property type="entry name" value="GWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="342" mass="36171" checksum="2ABFCEFEA46A08D0" modified="2009-05-26" version="1" fragment="single">RPYLAAYRAAMTLTTAVAILAVDFSAFPRRLAKTDSTRGVGLMDVGSGSFVLANALASRVARGLTTSSPTLRSTRWWSLIFLACARGLATHAMDYQQPVGEYGRHWNFFATLAVVDLCATATPPPPAFSSFAGLAILVAHQTSLLRGASPSGAGAAGVASSYGEYLLRDVPRGEGLLEQNKEGVGSIPGYVALYFLGAGLGRFVERSLCDAAKRASIRCWAWRWLLSLAVADAAFWAAAMTLHARCQAVSRRTANAAYCAWMLAFNLQVLLAFIAAGLLFPATPPVPKLLAAVNRRLLPTFLVANLLTGAVNGAMDTIHVGTLTAWASMVGYLSVVCVVGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ28</accession>
    <name>C1MJ28_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_38222</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055239.1">
        <property type="nucleotide sequence ID" value="XM_003055193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ28"/>
    <dbReference type="GeneID" id="9680399"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38222"/>
    <dbReference type="OMA" id="HATPRSC"/>
    <dbReference type="OrthoDB" id="406368at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40429">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40429:SF1">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="327" mass="34398" checksum="0FDB68A211F4C79F" modified="2009-05-26" version="1">MGDGRTTARVSPYARKPVYRLTTTMGKQTLSTRKTSFGDGVPFGKGTRDAFDKVYLSAEHAKCTPSNLSPGPAYTLSGCIGEVIDARYPTMPSPKFPSSDRNKLGTTRDSMHVLDPCAKKGISPPGPGKYELAPAVGAQVDSTKHSRPRHSLPRSTREQAQGLYDAATSKYNSAGNAWSPAAKYATVSSVGPQPESVKRTAPAAAFAKGGRWSSDKNAAQRPGPDRYTLPSGGVGKQTADYGATKKVTEPTAIFGTLKRDQRDKVMGGTVGMLSPGPCGSHATPRSCVGRQSSSREPTSPTVKFGTSTREPKLEVGSTGPGPGAYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ31</accession>
    <name>C1MJ31_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50789</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055241.1">
        <property type="nucleotide sequence ID" value="XM_003055195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ31"/>
    <dbReference type="GeneID" id="9680436"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50789"/>
    <dbReference type="OMA" id="LELEWQY"/>
    <dbReference type="OrthoDB" id="497909at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="434" mass="47044" checksum="4524758075515B24" modified="2009-05-26" version="1">MSATTSIAPARCRLCNASSPSTSRRARACAAARSRGARASDRIPTTTTSGADASSKPRDRRRIARPPRASSSADEPNASWDDLSGETGLSAQLRTCDALRKNLGAEMFAVDPSMASPDVVYTSQVHEARGAEQYNALMKAWRPLIKRTLLEFTYDVERAFCPEPGVLLVRWRAEWDGAFNPDAAMLDFVETKFPDYDGEEYRKLKKEVDDVRREWTGEREYSVKGITTIKVNDAGKIVTHEDKVMDKAGNMGLGDGGLGSGSGDWSGNGDRVGSESISDGDAQAKRERDEFAVTVFYNALKPPGVGAVSWFFDVLLELEWQYFRRQVGDDTTAIQSKQEFTNTIWTLLFTVVVLPSSIITWAILVALTSGEIAAPGGGDKYDQLIARDNAIERNQRARTGPQIGGLGGGGGGGGADAGLTPELLRSLYGQKIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJJ4</accession>
    <name>C1MJJ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54981</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056221.1">
        <property type="nucleotide sequence ID" value="XM_003056175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJJ4"/>
    <dbReference type="GeneID" id="9681407"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54981"/>
    <dbReference type="eggNOG" id="ENOG502SGQ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LLITHIM"/>
    <dbReference type="OrthoDB" id="445675at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34730:SF1">
        <property type="entry name" value="PARAQUAT-INDUCIBLE PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34730">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="425" mass="44312" checksum="3BDC196FD58C4239" modified="2009-05-26" version="1">MTPFNAASDAFQLHPDVRSYRTTLDVTVDQKYGFHAFLLATIASLLLGHVATHAHRVDVRASSSSAAAAATASDARPTRNVRHVRRRVVGVAIGASFLLLVVGARARSIAFEFEGLAGFALRVAAANGADAAAVRLLPIRPRSRGARRSLRAFPVVTLHPRFPFNAAANADDVANPRAFSLTSLTTTRGWPRRRSSAASVALFAFALLAPALSLLFFAALLALSLPPRPAAAAAASDDDDDGSDARAADGNRGGRESRRRSAESPPRRKIVNLREALVVAAEISRAWSALDVFVVSALAAATQIRRFAAFILGDACDGVDDVLRRMRSAEENGGGGADILPGMRGVDSCFDVETSLGWGWYVLAAAATLGYVSAAAIGRARFERGGGDEGGDEGGGGDEGDEYASWLDAEERGNGGGGGGGATDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJN9</accession>
    <name>C1MJN9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46476</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056246.1">
        <property type="nucleotide sequence ID" value="XM_003056200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJN9"/>
    <dbReference type="GeneID" id="9681878"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46476"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="361"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="461"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="494" mass="49948" checksum="392B2C280088D9FD" modified="2009-05-26" version="1">MSEREREARDSRVTQRSRQELALEEELTRDLKAIRKAARKQAKSERRGRAAAGAGEEEEDLEEDDDEVSDNNDAFGHSAFGRGAFGRPPPKSPPKRGTLAAAAAELDVAGFMRGRDARKDLDDFLSAEDFGGGAGGGGGSGGDAGEGEKKDTVGHEVSDTVGHHTLYGLRREADRSRAAIETATATATATAATTRGGGGGVGAKEEEEEEEEEAGGEGTVEEDPSVVERRRRDAVLAASGGAVTEADLVGVNFRPPPPSGGAGGDLIFDERGGSGASAAATPSSGSSLNNASASSTAWSTLSWLGGAFGGGASALASGVSHGVAALARGGGGGGAGGGAVAGGATKRVEEKEDEKKEDEAAPAASAGGDPLGASPPPPPPARRSSSSSSSSSPGDSPPSSPRRSEDRAERVEPPRWSPVSPAFVASLDDDDDDDDDDSHDDAAPPPRPESPLNDDDAGWLDASASGDVSGSDSPGGEEGDESAKRKSARRSLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJQ4</accession>
    <name>C1MJQ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55054</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055860.1">
        <property type="nucleotide sequence ID" value="XM_003055814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJQ4"/>
    <dbReference type="GeneID" id="9681634"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55054"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="85" mass="9680" checksum="0E96EEED11932E71" modified="2009-05-26" version="1">MDIHKRQLIHKTPPRRGKERERVSARARGGADGEAVRRGEQRPDRSRVNERTRRSIVRLTGQTKRTLKGKRGRSATTGRRGKSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJQ8</accession>
    <name>C1MJQ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55059</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055862.1">
        <property type="nucleotide sequence ID" value="XM_003055816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJQ8"/>
    <dbReference type="GeneID" id="9681884"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55059"/>
    <dbReference type="OrthoDB" id="1882595at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016636">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010024">
        <property type="term" value="P:phytochromobilin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009249">
        <property type="entry name" value="Ferredoxin-dep_bilin_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039715">
        <property type="entry name" value="ZCCHC10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491">
        <property type="entry name" value="ZCCHC10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491:SF0">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05996">
        <property type="entry name" value="Fe_bilin_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="551"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="650" mass="67631" checksum="CA23A9860F975D01" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKA5</accession>
    <name>C1MKA5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55257</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056352.1">
        <property type="nucleotide sequence ID" value="XM_003056306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKA5"/>
    <dbReference type="STRING" id="564608.C1MKA5"/>
    <dbReference type="GeneID" id="9681680"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55257"/>
    <dbReference type="OMA" id="MFGVADY"/>
    <dbReference type="OrthoDB" id="164285at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="153" mass="17257" checksum="A4EAD73660FB150F" modified="2009-05-26" version="1">MAKSDGAVRRRQAREEREDAIEERRAKAREEKNLCCGVSSLHVFFLLLFFLPTMFGVADYFFKFSEVPGGAHGALDPSQAVWREKLKAFYGENNPGKIGEIPKLLARFLSPRDLVRIVGPSGRRSSMTFPAFDSILFARFFPLHARSAATPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKG8</accession>
    <name>C1MKG8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55333</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056381.1">
        <property type="nucleotide sequence ID" value="XM_003056335.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9681949"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55333"/>
    <dbReference type="eggNOG" id="KOG2177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ATEYHEP"/>
    <dbReference type="OrthoDB" id="125363at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002116">
        <property type="term" value="C:semaphorin receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017154">
        <property type="term" value="F:semaphorin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030334">
        <property type="term" value="P:regulation of cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00603">
        <property type="entry name" value="IPT_PCSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031148">
        <property type="entry name" value="Plexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22625">
        <property type="entry name" value="PLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22625:SF70">
        <property type="entry name" value="PLEXIN A, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00429">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IPT/TIG" evidence="1">
        <location>
            <begin position="429"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="1">
        <location>
            <begin position="1256"/>
            <end position="1343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1346" mass="147418" checksum="E5FDC7298DE42A35" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM20</accession>
    <name>C1MM20_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_14761</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057318.1">
        <property type="nucleotide sequence ID" value="XM_003057272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM20"/>
    <dbReference type="STRING" id="564608.C1MM20"/>
    <dbReference type="GeneID" id="9682302"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14761"/>
    <dbReference type="eggNOG" id="KOG4562">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EENLWPH"/>
    <dbReference type="OrthoDB" id="205198at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1200">
        <property type="entry name" value="MAGE homology domain, winged helix WH1 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1210">
        <property type="entry name" value="MAGE homology domain, winged helix WH2 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037445">
        <property type="entry name" value="MAGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041898">
        <property type="entry name" value="MAGE_WH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041899">
        <property type="entry name" value="MAGE_WH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002190">
        <property type="entry name" value="MHD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736">
        <property type="entry name" value="MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736:SF14">
        <property type="entry name" value="NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01454">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01373">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAGE" evidence="1">
        <location>
            <begin position="13"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="234" mass="25506" checksum="225BA1EEC7637515" modified="2009-05-26" version="1" fragment="single">IASQEKDKLVAEVMRYVLFSQHKDGAPVQRSKISELITTLSPTLKRVNLAGYVIAQAQVKFVKVFGMEMKELSRMAHKKTGKDRTNAPTDPGKEYILKSTLPAAARKRWVDRAEDNAAKAFCITVCALVSISGGMIEEDALWKHLASLGVHQDDEDHPKLGNAKAAIARLCKQRYIMREKASAGGGEDGRDRYGYVLAERALDELGQDGVDAFVQGIMKGAGDDEGEQETGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM54</accession>
    <name>C1MM54_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_38820</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057339.1">
        <property type="nucleotide sequence ID" value="XM_003057293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM54"/>
    <dbReference type="GeneID" id="9682778"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38820"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="142" mass="14185" checksum="75B61815E33B1D93" modified="2009-05-26" version="1">MARSTVLATAVTVISPARDKCAAAVCGADCSLSRSCSSSDAISSFRRRFSALVVSTCDARARSSSAMRASFAAVAAVSSSCARVSVSNRACAAPNDSIAVARVARRFSISPLSVSACDTHVVRSSASGDAAGTRSSAAVAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN65</accession>
    <name>C1MN65_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_39047</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057049.1">
        <property type="nucleotide sequence ID" value="XM_003057003.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MN65"/>
    <dbReference type="GeneID" id="9682966"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39047"/>
    <dbReference type="OMA" id="YDEPKME"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="476"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="612"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="760"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="836"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="871"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="928"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1372"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2020"/>
            <end position="2050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2579"/>
            <end position="2632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2644"/>
            <end position="2673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2724"/>
            <end position="2746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2924"/>
            <end position="2967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2983"/>
            <end position="3031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3055"/>
            <end position="3102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3114"/>
            <end position="3137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3200"/>
            <end position="3219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3576"/>
            <end position="3640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3674"/>
            <end position="3696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3725"/>
            <end position="3764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3825"/>
            <end position="3873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4314"/>
            <end position="4372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4419"/>
            <end position="4469"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1673"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1746"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2233"/>
            <end position="2363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2448"/>
            <end position="2478"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3285"/>
            <end position="3372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3412"/>
            <end position="3492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="482"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="620"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="659"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="696"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="760"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="851"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="876"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="928"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="946"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1381"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1446"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1458"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2029"/>
            <end position="2047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="2582"/>
            <end position="2591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2592"/>
            <end position="2609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2649"/>
            <end position="2673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2733"/>
            <end position="2746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2983"/>
            <end position="2994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3007"/>
            <end position="3031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3055"/>
            <end position="3066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3089"/>
            <end position="3102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3589"/>
            <end position="3621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="3626"/>
            <end position="3635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="3725"/>
            <end position="3738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3739"/>
            <end position="3749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3831"/>
            <end position="3862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="4361"/>
            <end position="4371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="4437"/>
            <end position="4463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="4481" mass="473318" checksum="F1981F3CDA5F77A3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNN2</accession>
    <name>C1MNN2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional lysine-specific demethylase and histidyl-hydroxylase</fullName>
            <ecNumber evidence="3">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_55966</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ROX family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="3"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056677.1">
        <property type="nucleotide sequence ID" value="XM_003056631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNN2"/>
    <dbReference type="STRING" id="564608.C1MNN2"/>
    <dbReference type="GeneID" id="9682099"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55966"/>
    <dbReference type="eggNOG" id="KOG3706">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YLEYMGV"/>
    <dbReference type="OrthoDB" id="425950at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051864">
        <property type="term" value="F:histone H3K36 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032453">
        <property type="term" value="F:histone H3K4 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1500">
        <property type="entry name" value="JmjC domain-containing ribosomal oxygenase (ROX), dimer domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="NO66-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="MINA53 MYC INDUCED NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096:SF8">
        <property type="entry name" value="RIBOSOMAL OXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="JmjC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="5">
        <location>
            <begin position="241"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="451"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="520"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="526"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="639" mass="69764" checksum="033BC90DE8ABFC11" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNQ1</accession>
    <name>C1MNQ1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_55988</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057148.1">
        <property type="nucleotide sequence ID" value="XM_003057102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNQ1"/>
    <dbReference type="STRING" id="564608.C1MNQ1"/>
    <dbReference type="GeneID" id="9682109"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55988"/>
    <dbReference type="eggNOG" id="ENOG502S3MQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SWEERIT"/>
    <dbReference type="OrthoDB" id="507945at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33540">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN TSAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33540:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN TSAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="209"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="280" mass="30881" checksum="C475CFEC6808D908" modified="2009-05-26" version="1">MTSFAVRLPAPPRHRATPSRAAAARGPLCLRASYAASTADATETMGYERVPDEKEDVGGCNLRCASQRATEKVARMLAASARAGDVICLHGDVGAGKSVFSRAYVRAVAEDARLEVPSPTYLLQQVYDAHCERDAKNPKKLAKTSRPPVHHFDLYRVDDDPARAAKRLGLKTSFAEAACVVEWAERLRHLAPAHRLDVYVSMTSGARKAGQVEVKVSDEEDEEEEAGEAGEDGDGEEEEEEEEIDPAFVDARPRLIKLRPRSQEWVARVGRVHEKLMYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP33</accession>
    <name>C1MP33_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56129</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056750.1">
        <property type="nucleotide sequence ID" value="XM_003056704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP33"/>
    <dbReference type="GeneID" id="9682189"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56129"/>
    <dbReference type="OMA" id="KATRTAW"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="257" mass="27919" checksum="289407C424B2BD5C" modified="2009-05-26" version="1">MAVTTPNAKKNPAGVRHLSTPDILAAMMTDSDDDEPAALRAREELKATRTAWDDEEKENPKSPKSPLGKRGDGRGRDARVSSPTKNPLRSLLMNVNRGRDDRGADASSAAAASVVAETFDLRDDEVDRAKQLEVRHHESLKTHGMKPLAPPSRAAAETLAMTSRRRGDASAAIAATASHLAFFALAACWLFVVAVFIDVHGLWLPYYPNAFAVCTDGPRDVVRGAVSLARFMTGVAETPAKVAETGWRAWLSFFWPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPA8</accession>
    <name>C1MPA8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_38698</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol polyphosphate 5-phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056787.1">
        <property type="nucleotide sequence ID" value="XM_003056741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPA8"/>
    <dbReference type="STRING" id="564608.C1MPA8"/>
    <dbReference type="GeneID" id="9682693"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38698"/>
    <dbReference type="eggNOG" id="KOG0565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IMWISSA"/>
    <dbReference type="OrthoDB" id="62798at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF275">
        <property type="entry name" value="LD06095P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="3">
        <location>
            <begin position="34"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="407" mass="44237" checksum="00301872CB750DCE" modified="2009-05-26" version="1">MAADGSPPKGPTPPGALRVNTDAPTVEEDVLDARLLRVVAVTWNMNNRRFPEDVTPMLAPLFDGRTTPGDAESACDVFVVGVQEAPGKKEMEGFSDAVVHALGGFSKFAHLDAVTLDPGGWIQLHLFMRKKLVKYVSDFKVDAVSCGIGKVYGNKGAVGVSFSYAGASMCFLNAHLAAHLEKVKQRNADYHRIVKTMFAPKGRKSRALYDKENAQVARETADADGWGGADDLTSERIYPTAPSQPGTPIDPTRPTPATPKMFGGLFKKKGWSAADGFDLCVFMGDLNYRVEGNRTAVDKVMELGMWEVMHANDQLAVERNAGRAFAGWCEAELTFPPTYKLNRGSATEYDTSAKQRIPSWTDRIMWISSARGRLSCPHGADVYASVPGVRTSDHLPVLARIEVAIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPM5</accession>
    <name>C1MPM5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56960</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057980.1">
        <property type="nucleotide sequence ID" value="XM_003057934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPM5"/>
    <dbReference type="GeneID" id="9683050"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56960"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="243" mass="26015" checksum="241AA0B1E060A26E" modified="2009-05-26" version="1">MRAAPHAASPGRRCAFVRPSDPSSARRDFLLPALIGPAPEGGRRLAGPAESLKSYAAELARRNARARFVVDLQARPSRRPGRRASSRSPRSYFLPNIARPMGCASSTLTKTRISPDGDAGRARVARDSVASVGSAGEAPRGQRAFRETRSTTTTTSTVDDDFETRRAHIDRDAKAARTATAAAVAEARVAAPPICGRAGSGDDRTMMRRPNRNRPSVEVDEAAGFGFRRVLSHTGSHTTPSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPS8</accession>
    <name>C1MPS8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_16529</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CMC family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058003.1">
        <property type="nucleotide sequence ID" value="XM_003057957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPS8"/>
    <dbReference type="STRING" id="564608.C1MPS8"/>
    <dbReference type="GeneID" id="9683441"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16529"/>
    <dbReference type="eggNOG" id="ENOG502SBZE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RVEKYGH"/>
    <dbReference type="OrthoDB" id="532630at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977:SF1">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="87" mass="10191" checksum="3B750A2BBC080C83" modified="2009-05-26" version="1">MHPPLTLENHPLCKDVVIALKRCHRDNPWARAWGACNEQKWALDDCLKKQKLFKFRANHAKAKAQQDRLRRRVEKYGHATTNGQFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPS9</accession>
    <name>C1MPS9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_70902</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057637.1">
        <property type="nucleotide sequence ID" value="XM_003057591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPS9"/>
    <dbReference type="STRING" id="564608.C1MPS9"/>
    <dbReference type="GeneID" id="9683442"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70902"/>
    <dbReference type="eggNOG" id="KOG2509">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EQNCIDR"/>
    <dbReference type="OrthoDB" id="10264585at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000055">
        <property type="entry name" value="Serine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="11">
        <location>
            <begin position="79"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="202"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="289"/>
            <end position="292"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for serine binding" evidence="8">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="376" mass="41632" checksum="3AC5BE17A3298AE8" modified="2009-05-26" version="1">MKGKMDKEKRDALIEEGKALKDELAGLEQELGALETTMQIEGQKIPNDTHPDVPIGGEEVAALRREVGAKRDFSFAVANHVDVGERLGMFDFETGGKVCGSRFVYLTGAGAMLELALINWAMQKVVAKGFKPMVVPDLVRQSTMEKCGFQPRAENTQVYSIQDSELCLAGTAEILLGGVYMDEALEEKQLPIKMAAFSHCFRTEAGAAGAATRGMYRLHQFSKVEMFVVSTPEQSDAIHDELIAIEEEMYDELGFHFKVLDMSSEDLGAPAYRKFDIEAWMPALERYGEISSASNCTDYQARRLNIKYRPNPVDGKKQPLTHCHTLNATACAVPRMIITILENFQEEDGSVRVPEPLQPFMGGLKVLTPEDVAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPU2</accession>
    <name>C1MPU2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_46961</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058009.1">
        <property type="nucleotide sequence ID" value="XM_003057963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPU2"/>
    <dbReference type="STRING" id="564608.C1MPU2"/>
    <dbReference type="GeneID" id="9683072"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46961"/>
    <dbReference type="eggNOG" id="KOG0437">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KFIEWQF"/>
    <dbReference type="OrthoDB" id="10249672at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000001">
        <property type="entry name" value="Leucine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004493">
        <property type="entry name" value="Leu-tRNA-synth_Ia_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055416">
        <property type="entry name" value="RBD_LARS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00395">
        <property type="entry name" value="leuS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794:SF1">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24810">
        <property type="entry name" value="RBD_LARS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="17"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="209"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="11">
        <location>
            <begin position="804"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine--tRNA ligase RagD-binding" evidence="12">
        <location>
            <begin position="902"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF24810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH57960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1060" mass="116106" checksum="9D58DF3F7550D80A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPY2</accession>
    <name>C1MPY2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57086</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057666.1">
        <property type="nucleotide sequence ID" value="XM_003057620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPY2"/>
    <dbReference type="GeneID" id="9683466"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57086"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="12"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="101" mass="11921" checksum="EFB610F307B7BAB4" modified="2009-05-26" version="1">MDIQSMMDEASERERMIYAKFRLYDVDGTGTIDVHEIQELLKELRVVGVANDADRYLVKKLMHELGRDEDGVIDFEEFKVRRAHSLSPRRQLDQLGRRIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQW8</accession>
    <name>C1MQW8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57440</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057827.1">
        <property type="nucleotide sequence ID" value="XM_003057781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQW8"/>
    <dbReference type="GeneID" id="9683641"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57440"/>
    <dbReference type="OMA" id="WAVVPCC"/>
    <dbReference type="OrthoDB" id="568028at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971:SF3">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="499" mass="52287" checksum="7D0516CE52C89C98" modified="2009-05-26" version="1">MSGTRGIVRHGAAFSKHFAACTLDARRSRDDHLGTPDVVADDADADAASEKSRPRAFASADDVVDVVLAAKDGWGRELLAELCDDLGLPRFGADDAKGGASFGTTEVEILACVTETLDAGPDDGGGGGGGGGGGGGDGGGGASGGAPPRCCLHPTELRVRKRGRADGEEGWRTWVAAAADASRDGDGDGDATPRAADVDDATVVDAENTSNPEPEPSKKDSGKKKTHWHKIKKDNRASSFAALLVERFGVETLRLGAGVVDVAGGGGELAFELTTRWGVPCTIIDPRGSGVVLTSKHKRLLRSRAENGAMIDDAWAAASPLARGLRAEWRRRVPESVEHVKRSFDHTVMRDAALARLLRECSAIVGLHPDQATGAIVDAGLVLNKPWAVVPCCVFPKLYPTRADPVAGVAPVRTTDALVRHLMARAPGETRACELRCEGAKTAVWWIPREGEGGKDSAAAAPEGREDWPWPAPPRGTKSGARGPFAMPPGWRAPTDRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR38</accession>
    <name>C1MR38_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_67581</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058236.1">
        <property type="nucleotide sequence ID" value="XM_003058190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR38"/>
    <dbReference type="STRING" id="564608.C1MR38"/>
    <dbReference type="GeneID" id="9683302"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67581"/>
    <dbReference type="eggNOG" id="ENOG502QQ39">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WDTMATH"/>
    <dbReference type="OrthoDB" id="535167at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25828">
        <property type="entry name" value="CC_Cfap43"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="296"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="393"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="528"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH58187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="903" mass="98867" checksum="2B8BFD276BA27F15" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRA6</accession>
    <name>C1MRA6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Palmitoyl-protein thioesterase 1</fullName>
            <ecNumber evidence="1">3.1.2.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Palmitoyl-protein hydrolase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PPT</name>
        <name evidence="10" type="ORF">MICPUCDRAFT_33221</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.2.22" evidence="1"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057898.1">
        <property type="nucleotide sequence ID" value="XM_003057852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRA6"/>
    <dbReference type="STRING" id="564608.C1MRA6"/>
    <dbReference type="GlyCosmos" id="C1MRA6">
        <property type="glycosylation" value="1 site, No reported glycans"/>
    </dbReference>
    <dbReference type="GeneID" id="9683708"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33221"/>
    <dbReference type="eggNOG" id="KOG2541">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AEIACEN"/>
    <dbReference type="OrthoDB" id="10263094at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002472">
        <property type="entry name" value="Palm_thioest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF8">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02089">
        <property type="entry name" value="Palm_thioest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00414">
        <property type="entry name" value="PPTHIESTRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910614" description="Palmitoyl-protein thioesterase 1" evidence="9">
        <location>
            <begin position="20"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="147"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH57849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="398" mass="43365" checksum="4FA3C262EF4B9BD2" modified="2009-05-26" version="1">MRVVLLALAALALASGVDAATPTPTPRARSSSSPTPVVLWHGMGDNCCMGIRGIGELIAREIPGTHVHSVMLGSNPAEDAYRGFVGDVNAQVESQCETLALDARLAGGFHAIGFSQGGQFLRALAQRCGDRLNVRSLITLGGQHQGVAAPPRCGGDATAAAAAAEEEEEEDDGEEEEDDGASSASVGALCRAMTDAIARGAYARFTRDRIVQAQYFKDANDLASYRKHNPFLPDVNNELVDDGGEETRNETYRRNLLRLEKLVLFKWTDDTVVVPRESSWFGTYAENDRGGAIVPLREQRMYAEDWLGLRALDEAGRLKLLEIPGDHMTFTREWFVTNVIDAHLREGGGFKGAAGRWWLGGGPWRGGVRAFARWLRGATTRRRDDDDDDDDDDAYGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRC3</accession>
    <name>C1MRC3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP synthase CF1 delta chain chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ATPD</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_57603</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058280.1">
        <property type="nucleotide sequence ID" value="XM_003058234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRC3"/>
    <dbReference type="STRING" id="564608.C1MRC3"/>
    <dbReference type="GeneID" id="9683343"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57603"/>
    <dbReference type="eggNOG" id="KOG1662">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WFDLEMK"/>
    <dbReference type="OrthoDB" id="1262810at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="230" mass="24223" checksum="939CF8D550F3C7D5" modified="2009-05-26" version="1">MAAVISCSALAARVVSGSATGSRARGAVNLRAVKMTNAKGRGALVVSAASAVASGYASALVEACGDAKALESVHGDMETITAYMAANPSVGTFLSNPTMEAPQKKDVLAKLGKEADFHPFTKNFLNLLVDKKRIGNIEEIAEEFESLYCDSTDTQIATVTSAVKLENEQQFMIAKKIQEMTGAKNIKLKPEVDPSLLGGFVVKYGKDGSGFIDMSVQGQINTIKNEIVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRF3</accession>
    <name>C1MRF3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GPX2</name>
        <name evidence="5" type="ORF">MICPUCDRAFT_70207</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057917.1">
        <property type="nucleotide sequence ID" value="XM_003057871.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MRF3"/>
    <dbReference type="GeneID" id="9683736"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70207"/>
    <dbReference type="eggNOG" id="KOG1651">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PANQFGC"/>
    <dbReference type="OrthoDB" id="446890at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0711">Selenium</keyword>
    <keyword evidence="5" id="KW-0712">Selenocysteine</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-standard amino acid" description="Selenocysteine" evidence="5">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="290" mass="31466" checksum="0D7A50064283A97D" modified="2009-05-26" version="1">MPFALAAPAATPVVAARGRRRAERPRDRGVASVATRASRASDGDAASAIIVVDDVTRRESILSSAALLLALGGASPQRALAAEPIKSSFYDYTVMQYGKPFALSAFANDVTVVLNVASEUPLQNANYPALRSLYEKYHADGFGLIAFPANQFGCQAPGTSEMEREYAYRKFGFEFPVMDKIAVKDKPARCKGVDPASYESFKDDPDAYLTAPLIDDVTSSSPIAPVYAFLKQPPFEGEIPWNYTKFLVGRDGKVLRRYSPGDPLEQGMEKDVKRALAGEPLRAKPRGVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRP2</accession>
    <name>C1MRP2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_17157</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058909.1">
        <property type="nucleotide sequence ID" value="XM_003058863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRP2"/>
    <dbReference type="STRING" id="564608.C1MRP2"/>
    <dbReference type="GeneID" id="9683982"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17157"/>
    <dbReference type="eggNOG" id="KOG3315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YMVKFDD"/>
    <dbReference type="OrthoDB" id="10254842at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990070">
        <property type="term" value="C:TRAPPI protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000002">
        <property type="entry name" value="Trafficking protein particle complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="19277" checksum="1081C3F164E4F528" modified="2009-05-26" version="1" fragment="single">QGRTEVSLSAFAFLFSEIVQYHRTRASSVAELENKLSEAGQGVGSRMLEVLACRDKSNRRENRLQGILQFINTNVWRSLFGKSADSLEIYNDDEYVISDRDLLVNRFISVPKDFGDLNCGAFVAGIVKGVLADAGFEAEVSAYYAPVEGEARPRTNILMKFTSEVLEREARLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS24</accession>
    <name>C1MS24_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68347</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058972.1">
        <property type="nucleotide sequence ID" value="XM_003058926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS24"/>
    <dbReference type="GeneID" id="9684051"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68347"/>
    <dbReference type="OrthoDB" id="43435at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="499" mass="52434" checksum="3B3F1FCC5DE94086" modified="2009-05-26" version="1">MASALLARCRPGTTAPARASTPRRRGSATRARASSRNKNSNASTRGAHTALTAIASIASLLRRRASGGGAAVADAPAEVADPTRTRGEPLPILPDAPSRASDSAKLRTASGAPVQFLGISSEAFARERGEDALDVPARARASGVNYVHVSHKSLERGADLCGLRKLVGDDPVKRKKLFVTLGMSAKTLREIIAAEKKSAEKKKSGEKKSGGDGDGDGKGKGGVLGGVLGGGGAIYGNGSTERAITTHVERCLGALNTSYVDAFFFEDVERGDEVDVVASLRWMRRSLLVVPDKGRAGIDGVVRFVGAGTRDRCVGVRMLRCDKADVGGFGADVAYDYDAAAKASREEGARDTAAADSERPSSSFIGPATRPPCELDFLVARYDMTHVAAERSMFPAALIRDVPVIATPSNARELREAAEASGSMPSESDLLRFASAHPAVRVALASPADAAALRCVLSHTGLHTTALAWWTPILKDFSRRVSPPTPRFQRPPSTPFNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS31</accession>
    <name>C1MS31_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58326</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058615.1">
        <property type="nucleotide sequence ID" value="XM_003058569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS31"/>
    <dbReference type="GeneID" id="9684415"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58326"/>
    <dbReference type="OMA" id="KYKEAFM"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="216" mass="22893" checksum="96D7B5DDE279E104" modified="2009-05-26" version="1">MGIFSKGTRSKGVTLKHKQAGQSKNLQIAKKDRTAAYKYKEAFMKEAMARHLAAATAAVNGESVAPTSSAATTTPTLETKDVAAARARAMAAPKADTTKLGRANVGAKLRSKVDGKLISDPGTYLVGALRFEGRKRPTPKKKKKTGERGEDAGEGGAADDATKIGHLMRPLKGDEIDFATTVDTNVRLPAYARGKKTLAGKRKKNKKKNALAARGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS61</accession>
    <name>C1MS61_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">valine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_47388</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="2"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058990.1">
        <property type="nucleotide sequence ID" value="XM_003058944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS61"/>
    <dbReference type="STRING" id="564608.C1MS61"/>
    <dbReference type="GeneID" id="9684070"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47388"/>
    <dbReference type="eggNOG" id="KOG0432">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RQWYIRN"/>
    <dbReference type="OrthoDB" id="629407at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00817">
        <property type="entry name" value="ValRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.380:FF:000001">
        <property type="entry name" value="Valine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000014">
        <property type="entry name" value="Valine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000126">
        <property type="entry name" value="Valine--tRNA ligase chloroplastic/mitochondrial 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="entry name" value="Valyl-tRNA synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004349">
        <property type="entry name" value="PRK05729.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF93">
        <property type="entry name" value="VALINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="14">
        <location>
            <begin position="107"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="14">
        <location>
            <begin position="214"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="15">
        <location>
            <begin position="775"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="domain" description="Valyl-tRNA synthetase tRNA-binding arm" evidence="16">
        <location>
            <begin position="996"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="999"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH57445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1065" mass="117381" checksum="85C84DBE26776FEB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSC5</accession>
    <name>C1MSC5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58434</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058656.1">
        <property type="nucleotide sequence ID" value="XM_003058610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSC5"/>
    <dbReference type="GeneID" id="9684095"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58434"/>
    <dbReference type="eggNOG" id="ENOG502S5S6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WREWETE"/>
    <dbReference type="OrthoDB" id="568368at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="605" mass="64150" checksum="BB7CE6CA8D174156" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSI7</accession>
    <name>C1MSI7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_518</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058688.1">
        <property type="nucleotide sequence ID" value="XM_003058642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSI7"/>
    <dbReference type="STRING" id="564608.C1MSI7"/>
    <dbReference type="GeneID" id="9683822"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_518"/>
    <dbReference type="eggNOG" id="KOG0319">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PYVQRHF"/>
    <dbReference type="OrthoDB" id="5414888at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013934">
        <property type="entry name" value="Utp13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF15">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08625">
        <property type="entry name" value="Utp13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="56"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="98"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="140"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="392"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="457"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="532"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="574"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="623"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="665"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 13 C-terminal" evidence="7">
        <location>
            <begin position="719"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="331"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="856" mass="89051" checksum="D3C295B7B2824F22" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSP6</accession>
    <name>C1MSP6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_57771</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat ELP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058713.1">
        <property type="nucleotide sequence ID" value="XM_003058667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSP6"/>
    <dbReference type="STRING" id="564608.C1MSP6"/>
    <dbReference type="GeneID" id="9684152"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57771"/>
    <dbReference type="eggNOG" id="KOG1063">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DHECTHY"/>
    <dbReference type="OrthoDB" id="27911at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037289">
        <property type="entry name" value="Elp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44111">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44111:SF1">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="60"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="846"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="324"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="630"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="736"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="972"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="636"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="736"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="975"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH57168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1017" mass="103951" checksum="C15001E317BDA087" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSU5</accession>
    <name>C1MSU5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_17355</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058385.1">
        <property type="nucleotide sequence ID" value="XM_003058339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSU5"/>
    <dbReference type="STRING" id="564608.C1MSU5"/>
    <dbReference type="GeneID" id="9683862"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17355"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TAPKTCE"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000025">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase CYP19-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="171" mass="18527" checksum="E641C6A01D31D361" modified="2009-05-26" version="1" fragment="single">QHVGRVEIELFTRTFPITCENFRALCTGEKGCGVSGKPLHYKGAKMHRIIPGFMSQGGDTTAGDGTGGECIYGKRCFDDEWGGAAGDAYVRHSRPGLLSMANAGKNTNGSQFFITHAKTKWLDGKHVVFGQVLSGYEHVKWCEMNCGTFTGEPLYNVVIADCGEVTRGKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT45</accession>
    <name>C1MT45_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_57933</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058798.1">
        <property type="nucleotide sequence ID" value="XM_003058752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT45"/>
    <dbReference type="STRING" id="564608.C1MT45"/>
    <dbReference type="GeneID" id="9684237"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57933"/>
    <dbReference type="eggNOG" id="KOG1030">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MERASWG"/>
    <dbReference type="OrthoDB" id="566659at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd21669">
        <property type="entry name" value="SMP_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47264">
        <property type="entry name" value="OS01G0128800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47264:SF3">
        <property type="entry name" value="SYNAPTOTAGMIN-5 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="8">
        <location>
            <begin position="140"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="610"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="784"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="380"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="582"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="946"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="380"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="392"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="953"/>
            <end position="962"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="996" mass="109483" checksum="E760BCD6183F37AF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT50</accession>
    <name>C1MT50_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_57938</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058428.1">
        <property type="nucleotide sequence ID" value="XM_003058382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT50"/>
    <dbReference type="STRING" id="564608.C1MT50"/>
    <dbReference type="MEROPS" id="S01.474"/>
    <dbReference type="GeneID" id="9684241"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57938"/>
    <dbReference type="eggNOG" id="KOG1320">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RRMAIEC"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051201">
        <property type="entry name" value="Chloro_Bact_Ser_Proteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343">
        <property type="entry name" value="PEPTIDASE S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343:SF3">
        <property type="entry name" value="PROTEASE DO-LIKE 8, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="442"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="41"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="551" mass="56473" checksum="C0F3BD0134CDF877" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTL0</accession>
    <name>C1MTL0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Small ubiquitin-related modifier</fullName>
            <shortName evidence="1">SUMO</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_33538</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ubiquitin family. SUMO subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058879.1">
        <property type="nucleotide sequence ID" value="XM_003058833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTL0"/>
    <dbReference type="STRING" id="564608.C1MTL0"/>
    <dbReference type="GeneID" id="9683950"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33538"/>
    <dbReference type="eggNOG" id="KOG1769">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MKIYCAR"/>
    <dbReference type="OrthoDB" id="442921at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd16116">
        <property type="entry name" value="Ubl_Smt3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000202">
        <property type="entry name" value="Small ubiquitin-related modifier I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="13"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="91" mass="10445" checksum="A93A8769105FD098" modified="2009-05-26" version="1">MAEEEKKNDEKGDHINLKVKDQDNSEVHFKVRQTTKFSKIFDAFCARKSLQPDSVRFLFDGQRVNANMTPKDLDMEDGDSLDAMMEQVGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTY1</accession>
    <name>C1MTY1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58596</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059401.1">
        <property type="nucleotide sequence ID" value="XM_003059355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTY1"/>
    <dbReference type="GeneID" id="9684841"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58596"/>
    <dbReference type="OrthoDB" id="498883at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="19671" checksum="00B9D5D1253AA28B" modified="2009-05-26" version="1">MGKLKNYDCHKQKYYVPQNKPSWSVLNLKQAAKKIDKEKSASKKQALGKKKKVAQKLANRKGGRGLRNPANPEHKKILAKVRRVDGRLEPRLDARKESTTSQMNRLESNRQPPPAAHRFREPPSSADRSPRVLSSSASIYRRRRVPPPPPPARSQSKQLKKNKRSGRVSGRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU00</accession>
    <name>C1MU00_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58616</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059110.1">
        <property type="nucleotide sequence ID" value="XM_003059064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU00"/>
    <dbReference type="STRING" id="564608.C1MU00"/>
    <dbReference type="GeneID" id="9684565"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58616"/>
    <dbReference type="eggNOG" id="ENOG502SXUN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="363" mass="37842" checksum="78E660C383B1F96F" modified="2009-05-26" version="1">MSQDETNDGGGGGSAEAQAFTSVHDLVHYALASQPNKRSVPRTRARVESSSLERYIFLSRHVRRRRGRRAIARARPDAPSLPSPRGIHRNSAGLRQIYATCKEKGRIASKHGGGCRLLTANEHWKSQIRHALYTSPRFKRAGDGTDEWAPTSPDAPTPRTKTVRIDAGAATATATGTGTGAGGATPSGGSDHSNAGGGGGGGGTSRRATGAKTTAKAKKASRSPPKATAKGKEKASEETSSGDARGGGRKRARAESLAAKTTPEQSVTETTTSLPSARDPASVMSPSKPPSRTPLAEVKSAAAKRSPSLRGQTPPLLVSRSGSPTHDSLPAATFKVMVGNIAVTPKARDPTHRRKHRPARAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU60</accession>
    <name>C1MU60_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58678</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059141.1">
        <property type="nucleotide sequence ID" value="XM_003059095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU60"/>
    <dbReference type="GeneID" id="9684878"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58678"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="120" mass="13366" checksum="D46421006E53DE34" modified="2009-05-26" version="1">MNSQLAWGTPGTADSPLWFALPRSFVLVPLFYLRYGIFFRWHGYGPYRCNVVGVCAPLPGPNELGFIATWPGVFVDVFVLTFVMVLAECKLALSWRLWRAQLSRESNAGVLPGGARRASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUC2</accession>
    <name>C1MUC2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_17942</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059168.1">
        <property type="nucleotide sequence ID" value="XM_003059122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUC2"/>
    <dbReference type="STRING" id="564608.C1MUC2"/>
    <dbReference type="GeneID" id="9684913"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17942"/>
    <dbReference type="eggNOG" id="ENOG502QY75">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WYLFAEF"/>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039342">
        <property type="entry name" value="TGD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34675">
        <property type="entry name" value="PROTEIN TRIGALACTOSYLDIACYLGLYCEROL 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34675:SF1">
        <property type="entry name" value="PROTEIN TRIGALACTOSYLDIACYLGLYCEROL 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Mce/MlaD" evidence="2">
        <location>
            <begin position="75"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="331" mass="36148" checksum="12916B99AC4091E2" modified="2009-05-26" version="1">MDGSDQDESSSGSRTPRANPFELLYVALVKPLRDFGFGRTSVWEGGVGLFILGGMALTALVVNWVLGVNFNKMRSYQAFVEFPFACGIQVGTQVRVRGVKVGNVLSVRPNLERVEVLVEMDDDGIVIPRNSLVEANQSGLIAETIIDITPEIPIPKAQWGPLDSGCEGEGLVVCDRGKIQGTPGVSMDELVGICTKLAREMDSNDGIAKMFATAETAQDLMKNLEPLLLEAAEIAKELRPMLQNVQEQGTLDTIELLAGHATKAVTDIRELKRTILTDDNQEMLRQSITIMTKTLQHMEKVSGDISSVSGDPATRQNLRHLIQCLSRLVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUP8</accession>
    <name>C1MUP8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_8648</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059534.1">
        <property type="nucleotide sequence ID" value="XM_003059488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUP8"/>
    <dbReference type="STRING" id="564608.C1MUP8"/>
    <dbReference type="GeneID" id="9684673"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8648"/>
    <dbReference type="eggNOG" id="ENOG502QUJW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="REVDPFN"/>
    <dbReference type="OrthoDB" id="2014339at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021920">
        <property type="entry name" value="DUF3531"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46737">
        <property type="entry name" value="OS02G0827600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46737:SF2">
        <property type="entry name" value="OS02G0827600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12049">
        <property type="entry name" value="DUF3531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="146" mass="16602" checksum="9D6F548447F78414" modified="2009-05-26" version="1" fragment="single">MMVKFDEFKSGNLWIWVESHNAIAEREQPLLDEVFKAWFVLGKLGGFNSENAQVQSNFFEVSNMKYDMDLANGDGDGDVNRCVFHALGEPEYRGKWARCWVDMGSADEMGMDVLINSLITFSKEYFGLKTLVIGGTNIVDDWPVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUT4</accession>
    <name>C1MUT4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_33987</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059249.1">
        <property type="nucleotide sequence ID" value="XM_003059203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUT4"/>
    <dbReference type="STRING" id="564608.C1MUT4"/>
    <dbReference type="GeneID" id="9684689"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33987"/>
    <dbReference type="eggNOG" id="ENOG502RZ2D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FARCTGD"/>
    <dbReference type="OrthoDB" id="497692at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045039">
        <property type="entry name" value="NSI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43626">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43626:SF4">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="167" mass="18476" checksum="53AE048ADCAE5E4D" modified="2009-05-26" version="1">MPPTTFSNADAYFTEKLGAEFVFGQRPDADLDELNALFATVGFPQRDPVRLKRALVNSHLIVWVVATDKNKSRATHVGQVIGFARVTSDKVFNGTIWDVVVSPEWQGAGIGRGMVERLVDKMLEEGINNVSLYAEPAVVKLYNDCGFEIDPGGTTGMAFRVKSRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUY0</accession>
    <name>C1MUY0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_69693</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059270.1">
        <property type="nucleotide sequence ID" value="XM_003059224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUY0"/>
    <dbReference type="GeneID" id="9685019"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69693"/>
    <dbReference type="OMA" id="KCEPAGK"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="396" mass="41190" checksum="0DD1C332B51AD1BB" modified="2009-05-26" version="1">MQYSMYIERFRSLTQRSTEVGDVTSARALGAKCRRPLRRLGVFAARRLLVAETVIPEVVSPGVPVVAVSGVCIITAVFGVIAVARVMVISGGRGLRRGGGGLRRGGGGLRRGGGGLRHRRLVISGGGGLRHRRWVISGGGGLRRGGGGLRRGGGGLRRGGGGLRRGGGGLRRRRLGISGGGGLRHRRWGISGGGGLRRGGGGLRRGGGGLRRGGGGLRRGGGGLRRGGGGLRHRRLSISGGGGLRHRRWVISGGGGLRRGGGGLRRGGGGLRRWVISGGGGLRRGGGGLRRLVISGGGGLRRFRGGGLRRGGGGLRLFRGGGIRRFRGGRLRRFRGGGIRRFRGVGRVGSIVERHRARVETLRAGDIRFVRVARSDEVAVARVDAPFVVDIDGAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUY4</accession>
    <name>C1MUY4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_17965</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059273.1">
        <property type="nucleotide sequence ID" value="XM_003059227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUY4"/>
    <dbReference type="STRING" id="564608.C1MUY4"/>
    <dbReference type="GeneID" id="9684713"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17965"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GAKTHVW"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="464" mass="49032" checksum="3607BC793707DF1C" modified="2009-05-26" version="1">MLAISRASALSPTASRASRGSEPARRRVAVPARAAATARRRRAIATSSSRDRRVVAPRASSSSSSSSSSSSSSEAAAAAAAADDASRAPSASSRRGVLGLGAAALASTAAARVPLAFADDDVVVASPSPAAARGAVLVTGANSGVGFSAAKQLAARGERVVLACRTVEKANVARTAILEKVPGAAIDVLPAAGLEMADLASVSDYAKAFKDSGIPLNVLVCNAGIMAVPLGHTRQNHEMHFGVNHLAHFLLQDALVPALRDRVERDGKRGRVVACSSIANTLGDLAVDLDDLDWNDRTYNEWTAYCASKAENVLMTDQLAIREPGISSNAFHPGIVTTNLVRYILPDLTAENRDPEAEAQTRNGKMLKKMGIRDADEGAKTHVWLASDPAAEDVSGEFFIDPGVTYPGATRRQLVDGGDWFLLTGEEFGARQLGMPDKLFEWRNERNGEVLWDKSMEMISKYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV48</accession>
    <name>C1MV48_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_7579</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. GNAT subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059311.1">
        <property type="nucleotide sequence ID" value="XM_003059265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV48"/>
    <dbReference type="STRING" id="564608.C1MV48"/>
    <dbReference type="GeneID" id="9684751"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7579"/>
    <dbReference type="eggNOG" id="KOG4135">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WHVPRYH"/>
    <dbReference type="OrthoDB" id="5043642at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039135">
        <property type="entry name" value="NAT9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256:SF16">
        <property type="entry name" value="ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256">
        <property type="entry name" value="N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="13"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="189" mass="20875" checksum="6D70BA859226CBA5" modified="2009-05-26" version="1" fragment="single">MRANANVTLRGSRCVLVPYRPEHVETYHAWMLDPETLAATASEPLTMEEEIEAQRSWANDETKLTFIVLDVDAAGDARRDGDGDGDGAPRADLGVMCGDVNLYWNVADDVLASAEIEVMVAEKRSRRKGIASEALEMCMAYAWKTMHVTTFVAKIGLGNAASLALFTEKLGFRETSRETRIFREATAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVT8</accession>
    <name>C1MVT8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_47713</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059807.1">
        <property type="nucleotide sequence ID" value="XM_003059761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVT8"/>
    <dbReference type="GeneID" id="9685246"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47713"/>
    <dbReference type="eggNOG" id="ENOG502QR3Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2018137at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31033:SF18">
        <property type="entry name" value="OS06G0115800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31033">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="461" mass="47234" checksum="9DD0884EECE9BA9A" modified="2009-05-26" version="1">MAREKVDGDEDDCPRAASPCPFLLAMQKGASDLSIADDWISPHGATFQAVHGERGVLPLRRDDDDDGGDDDGDDAFYDAIESAAAPATPTPRARCPLRGLFATTSTPRSRSGDEEEDEAAAPARSDAWSFRGALARRVASISFSALGRVGGGGGGGGWRKPSGGGGGNGDDARASKKTADGGSSASAKNNAPPASKSSTASTSAASASVEASVKSFAASKCPFAKVPGFDALVKSMLTAAERPFKCPAPIVAMRAAVAALPQVKRLRPEPLQSKLLAVAATAAFVNAPLGALREHTEKFSFQWFVAIHASIPFVASLRKAVGMPKLAILFTVAAAVMGQYAGSRGERARLRLSAAAGKENQNKNQNIRNPNRDASAERRRAKKRGAPEDDAPPPLGGRASSRRVRVGGGGDVSGGARSRGGGLPGLPKLRGLGSPVLASATAAAAAAAGDDAAPRRRVAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW00</accession>
    <name>C1MW00_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Dexh-box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_59573</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059841.1">
        <property type="nucleotide sequence ID" value="XM_003059795.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MW00"/>
    <dbReference type="GeneID" id="9685280"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59573"/>
    <dbReference type="eggNOG" id="KOG0391">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RTHIDPM"/>
    <dbReference type="OrthoDB" id="372624at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18003">
        <property type="entry name" value="DEXQc_SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000005">
        <property type="entry name" value="Photoperiod-independent early flowering 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSA" evidence="14">
        <location>
            <begin position="334"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="841"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="1379"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="192"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="474"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="576"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="728"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1538"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1584"/>
            <end position="1710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1837"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1885"/>
            <end position="2006"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1762"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="523"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="555"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="576"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="609"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="665"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="689"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="730"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="741"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1609"/>
            <end position="1622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1632"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1670"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1683"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1845"/>
            <end position="1855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1916"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1949"/>
            <end position="1958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1959"/>
            <end position="1972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1979"/>
            <end position="2006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH55793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2006" mass="216193" checksum="F9011715E6DF4DBB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW11</accession>
    <name>C1MW11_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="3 6">2.1.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_34318</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = 2-dehydropantoate + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PanB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="3 6"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060133.1">
        <property type="nucleotide sequence ID" value="XM_003060087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW11"/>
    <dbReference type="STRING" id="564608.C1MW11"/>
    <dbReference type="GeneID" id="9685571"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34318"/>
    <dbReference type="eggNOG" id="KOG2949">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VLVWTDM"/>
    <dbReference type="OrthoDB" id="425211at2759"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000003">
        <property type="entry name" value="3-methyl-2-oxobutanoate hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001452">
        <property type="entry name" value="PRK00311.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881:SF0">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="336" mass="35082" checksum="2C3296F906CE5A93" modified="2009-05-26" version="1">MSSKPRDVVYGGPKPPVERFTLRKLAAKYRRGERITMVTAYDYPSAVHVDLAGVDVCLVGDSAAMVVHGHDTTLPITLEEMLSHFRAVARGASRPLLIGDLPFGSYERDPAQAIETATRIMKEGGMDAVKARSLEGGSPARVRAARALVDAGVAVMGHVGLTPQSISVLGGFRPQGRSHDEAADIVERALALQDAGCFSGAFFVLECVPAAVAAATTAALRVPTIGIGAGGACSGQVLVYHDLLGFTQHPHHAAVTPKFCKRYANVGEVITGALAAFREEVENGSFPSVAFSPYELREGDAARFAAALRERGLGEAATAVEELEGGEKSGGGAASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWI8</accession>
    <name>C1MWI8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_18587</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060224.1">
        <property type="nucleotide sequence ID" value="XM_003060178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWI8"/>
    <dbReference type="STRING" id="564608.C1MWI8"/>
    <dbReference type="GeneID" id="9685370"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18587"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HACTAGS"/>
    <dbReference type="OrthoDB" id="498026at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="67"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="139" mass="14961" checksum="F5C33DEB3A3E8437" modified="2009-05-26" version="1" fragment="single">MAEVYLHDAARNGDVEAINKAVAAGQDVNARDAHKRTPLHLAAHAGQMDAAKFLVASGAKLHLEATDGVNALHFACIRGHHDLARELVNLGANAKAVTYKGENALHFAARTGDVKLISMLLRKQVSALTRSKRGKRPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWR9</accession>
    <name>C1MWR9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_59229</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059972.1">
        <property type="nucleotide sequence ID" value="XM_003059926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWR9"/>
    <dbReference type="STRING" id="564608.C1MWR9"/>
    <dbReference type="GeneID" id="9685110"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59229"/>
    <dbReference type="eggNOG" id="KOG2855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YIFYKDH"/>
    <dbReference type="OrthoDB" id="415590at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050306">
        <property type="entry name" value="PfkB_Carbo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43085:SF57">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43085">
        <property type="entry name" value="HEXOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="4">
        <location>
            <begin position="74"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="349" mass="36238" checksum="1903BC5D1F8F4017" modified="2009-05-26" version="1">MACAVAAAASFARVGVGVGVDSRARPRASATFRSSSRVAVRSRARAARVAAAAEERVTVIGEALWDSLPAGLFLGGAPANVACHLNELGRPATIVSRVGDDELGREVLRRLTSRGLDTSSIQVDDGGVATGFVVVTMKGAMPSYDIVQPSAWDAMTASDDLVAAASGNVVVYGSLAQRDARSREAIKAAAAAASRRVFDVNLRKPFIDPELCVEHATGCWLLKLNDEELPEMAGWLGIESSESSDASDLAEKVHAKLGCEMLCVTRGGDGAAIVSKTEGFVQHPGFEVTPVDTVGAGDSFLATLLDRLLSGAGAAEALERACRVGAFVATQQGATPFHDQTGIDALKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX02</accession>
    <name>C1MX02_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59314</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059721.1">
        <property type="nucleotide sequence ID" value="XM_003059675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX02"/>
    <dbReference type="GeneID" id="9685449"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59314"/>
    <dbReference type="OMA" id="GCAYVIE"/>
    <dbReference type="OrthoDB" id="497896at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="2">
        <location>
            <begin position="162"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="317" mass="32441" checksum="10DC8EE81B7C9334" modified="2009-05-26" version="1">MAGGYTGAALGLAAPAATEKCCNRMLTKTATPSVSVRTARSPPARTRTPVASMASSSLRIDALARVASTPVASRPPRGRATPPRVARTTTVETISSPRGSDASAPGRRASLFGLAAAAAAATSSRPPRARAEISTPKGYDDPVVTPGGFNAWASTSDAIGCAYVIEWPSGWCALSDLSSARTVGVDASFKNPADEASTLAVFVSDVPVGQRSVADQGSLDALARSRADSAPRQQNIGKRKRKTPLASGGGDALTYDIETKVGGGTAGRFGAAVELVSITVVGGKEYLIRATASASSWPGEKARLRRAVESFAFTGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX06</accession>
    <name>C1MX06_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_59318</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060013.1">
        <property type="nucleotide sequence ID" value="XM_003059967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX06"/>
    <dbReference type="STRING" id="564608.C1MX06"/>
    <dbReference type="GeneID" id="9685101"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59318"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LMAVESH"/>
    <dbReference type="OrthoDB" id="547759at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000180">
        <property type="entry name" value="serine/threonine-protein kinase STY46-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF255">
        <property type="entry name" value="OS02G0527600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ENTH" evidence="11">
        <location>
            <begin position="52"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="725"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="375"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="563"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="624"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="642"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="752"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH55965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="992" mass="105847" checksum="C3A841CAACAF9CB8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX27</accession>
    <name>C1MX27_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60007</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060325.1">
        <property type="nucleotide sequence ID" value="XM_003060279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX27"/>
    <dbReference type="GeneID" id="9686055"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60007"/>
    <dbReference type="OMA" id="MACIASQ"/>
    <dbReference type="OrthoDB" id="10676909at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="407" mass="41605" checksum="2EA28AA071CF6DAB" modified="2009-05-26" version="1">MACIASQTLAIGANDLGARRLHARVAKRATAPGHAASRLNHVGGKTNVISAPAVTVDAPTADAPTTTKKTARPPSEMKHCIVCPFVGGDVEEGAYYSFTKERPQGVLMASETWDGVSVYIVKTPYGGGTVRLAKKAADSAPTTSLFGKMKETVMGAAKEAAPAAPPAPPPPPPASEPVAPAAVAITSKPPAVVRDRGGKSGVSVFERGVGVSSWDGFEIGYELDLVVEVPVPATETAAAAVAEAPAHAASNILSRPTTDQATKSGAAVFGNGVGIVSWTPGSLDAPEMPVASEAAVAAAVAAVETAASTNGRLASVDDIAIAAEFRRRTTTEAAAMEAGTFVEKKVVEEKKVVEEKKVAEPIVAAPAPEAPKAEALDAVDDKEFKFVATLWALNACIVAYKLLISPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX74</accession>
    <name>C1MX74_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">YEATS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_7691</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060346.1">
        <property type="nucleotide sequence ID" value="XM_003060300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX74"/>
    <dbReference type="STRING" id="564608.C1MX74"/>
    <dbReference type="GeneID" id="9685784"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7691"/>
    <dbReference type="eggNOG" id="KOG3149">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VMSEVYE"/>
    <dbReference type="OrthoDB" id="494822at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16910">
        <property type="entry name" value="YEATS_TFIID14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573:SF1">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="YEATS" evidence="5">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="149" mass="17124" checksum="F1428123AE56B991" modified="2009-05-26" version="1" fragment="single">RVKGKELVVPICYGTCAYWLGKKADEYHSHKWTVYLRGAEHEDLSHCIEKVVFNLHPSFKEPVRVLEKPPYEVTETGWGEFEIGVTVHFASDAGEKPLELSAPLKLYLEDTEKGKAESKAAKKPVVKEKYEEIVFHEPREEFAKRIEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXQ0</accession>
    <name>C1MXQ0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glycerophosphodiester phosphodiesterase</fullName>
            <ecNumber evidence="1">3.1.4.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_60240</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a sn-glycero-3-phosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12969"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:83408"/>
            <dbReference type="EC" id="3.1.4.46"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.4.46" evidence="1"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060730.1">
        <property type="nucleotide sequence ID" value="XM_003060684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXQ0"/>
    <dbReference type="STRING" id="564608.C1MXQ0"/>
    <dbReference type="GeneID" id="9685874"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60240"/>
    <dbReference type="eggNOG" id="KOG2258">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CPECVYW"/>
    <dbReference type="OrthoDB" id="1058301at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044236">
        <property type="entry name" value="GDPD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47449">
        <property type="entry name" value="GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47449:SF2">
        <property type="entry name" value="GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13653">
        <property type="entry name" value="GDPD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910551" description="glycerophosphodiester phosphodiesterase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="6">
        <location>
            <begin position="53"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="375"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="407" mass="42318" checksum="BAD9511108AE75FE" modified="2009-05-26" version="1">MYALVVVLAWYVSGGRTAPSPVASSSSSSPVVLAPSPTFCARRDPIVCAHGTVGSADWPRSMGRRPFPNTVPALAAAVAAGHECVEVDASRTKDDHLVALHPRELKMLTGGRVGNPGDLTLAEIMSLTMPGAKEYRVATFAEAMAVVMNKGLTQITVDFKDGPPRREEGFASAVTREIARLGRSHGSGRSQSATTACPECVYWGKSDEIALDVLELTRGDAKARLSRAFLSAHPTVSFNPDTPRCLSTPLLTPFDSTPTSPRMHPTLARPKVGYSVANFSRAIIDAGLHRLAGREDVTSRAYVAAAQSEMASEALIAEVAAATAEDAPHGKTRTYAWTVNAPAATAAVVNAGVDGVVTDEPELVARVVRKLRGRCGSGGGGDGGGGGSGGGGWFARGASSAAKDEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYK8</accession>
    <name>C1MYK8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_3730</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060585.1">
        <property type="nucleotide sequence ID" value="XM_003060539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYK8"/>
    <dbReference type="STRING" id="564608.C1MYK8"/>
    <dbReference type="GeneID" id="9686022"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3730"/>
    <dbReference type="eggNOG" id="ENOG502QU0Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YNWIEST"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="9">
        <location>
            <begin position="1"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH55354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="361" mass="40590" checksum="E7501882720F5D9A" modified="2009-05-26" version="1" fragment="single">YFLGSNTYYLMVRGASPTFRCEVDEVLDAAADLGVTVLRTWAFSDGAGEWRALQRAPGVYDEATFRGLGAFSSDWFPYDRAGKRGIRLLVAFANYWQHYGGADAYNRWSFLAGEGRCDGELACRDDFFSDPYARRLYKNHVAAVIGRVNTFTGVRYRDDPAIFGWNLMNEPRSTKDLTSLEYNVSSNTGDALQAWIEEMTPHVKSLDPNHLLTVGSESFFGPSSPLYLYANPGPWAQLEGVDFVRNHAVPGIDFATMHVYVDQWLCVERGATKTEKLNYTERWLRAHVQDADKLGKPLVVEEFGKSTPSSRITVGRGLQPGERVHGGPGDFYVRDEFFESVYRIVEKSKRDGGSGQGTNFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYL5</accession>
    <name>C1MYL5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_47841</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060589.1">
        <property type="nucleotide sequence ID" value="XM_003060543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYL5"/>
    <dbReference type="GeneID" id="9686026"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47841"/>
    <dbReference type="eggNOG" id="KOG1676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VCKNITH"/>
    <dbReference type="OrthoDB" id="5204190at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="407"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="372"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="445" mass="43370" checksum="C8DB8358BBD99EFB" modified="2009-05-26" version="1">MGGGGLGPLPPPPGMHQGGYGGYGGARGGGGGMGMGPGGPGPGPGPGPGPGPDPRYQRGPPGPPMGGGMGMGPGPGPGYGGGYGGGPGPGPGYGGGGGPGPGYGGGGSRGGGGGAPIPGAAYEEIMCPTEAAGKIIGHGGDTINSIQAKSGAHVKIQPSHEVVPGQPRRITISGVPGAVADAAQLVNDIIRETELKHSRASLPGGGGGGHSGGGRDSNQIEMPVPVPTEMIGRVIGRGGETIRRLQEESGARMQVERDLGRVMIKGGADECTRAKELVLDILNAPPPTAGGGGGGGGTVRHVMPAGGCEGKIIGKGGDSIRDLCARTGAKIQIDKDAASVTISGRQDQVDAAIALVQAIIDEGPTVYMKPGGLPGEDPRPYEPGLGRGGGGGTGGYAAASAGADGGDGAKPLWEAHKSPEGYTYYYNTIDGSTTWDMPADYDGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYQ9</accession>
    <name>C1MYQ9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glycine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_27874</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Gly) + glycine + ATP = glycyl-tRNA(Gly) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="2"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060611.1">
        <property type="nucleotide sequence ID" value="XM_003060565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYQ9"/>
    <dbReference type="STRING" id="564608.C1MYQ9"/>
    <dbReference type="GeneID" id="9685756"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27874"/>
    <dbReference type="eggNOG" id="ENOG502QS5T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LPIPKRM"/>
    <dbReference type="OrthoDB" id="1545at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.180">
        <property type="entry name" value="Class II aaRS and biotin synthetases, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00255">
        <property type="entry name" value="Gly_tRNA_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015944">
        <property type="entry name" value="Gly-tRNA-synth_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002310">
        <property type="entry name" value="Gly-tRNA_ligase_asu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00211">
        <property type="entry name" value="glyS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30075:SF2">
        <property type="entry name" value="GLYCINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30075">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02091">
        <property type="entry name" value="tRNA-synt_2e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02092">
        <property type="entry name" value="tRNA_synt_2f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01044">
        <property type="entry name" value="TRNASYNTHGA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH55380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="963" mass="104509" checksum="9C1C77891A4D97EA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZI7</accession>
    <name>C1MZI7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63420</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060960.1">
        <property type="nucleotide sequence ID" value="XM_003060914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZI7"/>
    <dbReference type="GeneID" id="9686666"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63420"/>
    <dbReference type="eggNOG" id="ENOG502SRJG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45188at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="194" mass="21205" checksum="D47FB4B739C01B6B" modified="2009-05-26" version="1">MVVRREPPEDELADLGRRLAENLPGGEGYAQTMRDETRRTADELRANPSQIPAALASTCDLELNARDVYGDGDQSPLEDSLDASNPRNAQRLRDVWCTGGDLNQLLATGRVTAFFRYCFAGDAKLVGDFIAAARADPDPDALRNLLERRESQMHVSPLFAVVAGARMRVIFDDQVVDRGTTSSARVSSSPRAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1U7</accession>
    <name>C1N1U7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_21196</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062180.1">
        <property type="nucleotide sequence ID" value="XM_003062134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1U7"/>
    <dbReference type="STRING" id="564608.C1N1U7"/>
    <dbReference type="GeneID" id="9687416"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21196"/>
    <dbReference type="eggNOG" id="ENOG502QPXS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EGCKDAN"/>
    <dbReference type="OrthoDB" id="1898560at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01029">
        <property type="entry name" value="TOPRIM_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034154">
        <property type="entry name" value="TOPRIM_DnaG/twinkle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027032">
        <property type="entry name" value="Twinkle-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12873">
        <property type="entry name" value="T7-LIKE MITOCHONDRIAL DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12873:SF0">
        <property type="entry name" value="TWINKLE MTDNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56731">
        <property type="entry name" value="DNA primase core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Toprim" evidence="2">
        <location>
            <begin position="182"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="SF4 helicase" evidence="3">
        <location>
            <begin position="328"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="597" mass="66042" checksum="62639DFEE80C5056" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1X6</accession>
    <name>C1N1X6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_51771</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062194.1">
        <property type="nucleotide sequence ID" value="XM_003062148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1X6"/>
    <dbReference type="STRING" id="564608.C1N1X6"/>
    <dbReference type="GeneID" id="9687431"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51771"/>
    <dbReference type="eggNOG" id="KOG0266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DGMVSFW"/>
    <dbReference type="OrthoDB" id="75172at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051242">
        <property type="entry name" value="WD-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324:SF4">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="66"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="107"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="172"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="326"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="371"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="413"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="908"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="955"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1110"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="925"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="967"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="978"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="989"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1142" mass="122925" checksum="161AE7AD5A9C6EEC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N210</accession>
    <name>C1N210_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51808</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062008.1">
        <property type="nucleotide sequence ID" value="XM_003061962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N210"/>
    <dbReference type="STRING" id="564608.C1N210"/>
    <dbReference type="GeneID" id="9687650"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51808"/>
    <dbReference type="eggNOG" id="ENOG502QSV6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RIDHTHS"/>
    <dbReference type="OrthoDB" id="2015023at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009704">
        <property type="term" value="P:de-etiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090333">
        <property type="term" value="P:regulation of stomatal closure"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044690">
        <property type="entry name" value="CAS_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34209:SF1">
        <property type="entry name" value="CALCIUM SENSING RECEPTOR, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34209">
        <property type="entry name" value="RHODANESE/CELL CYCLE CONTROL PHOSPHATASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="274"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="386" mass="39291" checksum="09472E163EBBBAA8" modified="2009-05-26" version="1">MDIVVSRERAKRFSTCDVRRTSSDTNGFADAVVSSRSTDPRAALIHRARRSMAALTTVPLVLGAKPALRGAKVASKAAPKASDLFTLFDSIDKTADKIEGAFGAAAGAAGKAADAVSAAATVAKPFAEKAVDAAAPLLDATGKYAERTVAPLAGEAIKTAGSAAGGVAGSAANAIKSRGIDVEPVAGAAGAAGKLAGDFATTTAAPALEKFGDYLSTASPTDLAELGAGVLAAYFIAPALLGVVASSARGYAGSGAFHLALFFRPVEAYDDVLNKKNVVVVDVRRENEVERGEVDFPRRAASRVLQVPREQLRGNFKNSSAVDANLTALKVANLKGVKRGTKVYLLDANGGDAPKVAKALTAQGFGKVYVIQGGFNGWASAGLGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N217</accession>
    <name>C1N217_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48449</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062012.1">
        <property type="nucleotide sequence ID" value="XM_003061966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N217"/>
    <dbReference type="GeneID" id="9687653"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48449"/>
    <dbReference type="eggNOG" id="ENOG502SGQ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="568337at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="632"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="690"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1013"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="349"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="425"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="694"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="729"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="757"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="782"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="818"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="905"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="944"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1021"/>
            <end position="1045"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1121" mass="117436" checksum="D67E29779268B5C5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2D7</accession>
    <name>C1N2D7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51490</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062068.1">
        <property type="nucleotide sequence ID" value="XM_003062022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2D7"/>
    <dbReference type="GeneID" id="9687293"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51490"/>
    <dbReference type="OMA" id="TRENKVM"/>
    <dbReference type="OrthoDB" id="10461740at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056575">
        <property type="entry name" value="WH_MCM3_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23191">
        <property type="entry name" value="WHD_MCM3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM3-like winged helix" evidence="2">
        <location>
            <begin position="398"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="462" mass="49160" checksum="106A394037E672F7" modified="2009-05-26" version="1">MATTATTVTAPVRIETRSSVVFARVRGSGRHSRRRARARALALSVLASASLRVSRTVMESSPRAVAPLADVTNPKARQSAISSSVTTPTPPSASAKATPARASDDDEPSTTAPTTTEPREAAAEDADLAPEISPAPENAAAAADAAADAADADAPAAKKPKKLPIEAPPKPMSRALPDALAEWKDYAEKELTQLHRFRKQQLLDWWLVKGAINCAVVSCPVAALRAEIRALRDNGVYGSSMVPYLQCLRGILDTVDAHADDVDENTLEEFSESEDEEEEEEEDDEDDDAAEDSYDSEGGEEAYDSENDAYDSEAEAECGDDADADAGGGAKKQGLRVVEGMVASPPAAAAAAAAAARAQSHSRPKPTVVPVRLKKPSKGGSKSSKGASERSEYQIEKRARYNLFARFLGSYFASERVEKAGVAELLNHPDAAGFGDDEVVSFLDMMTRENKVMLDEGTVWII</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2E9</accession>
    <name>C1N2E9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fanciful K+ uptake-b family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_9626</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061862.1">
        <property type="nucleotide sequence ID" value="XM_003061816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2E9"/>
    <dbReference type="STRING" id="564608.C1N2E9"/>
    <dbReference type="GeneID" id="9687514"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9626"/>
    <dbReference type="OMA" id="MYPLATI"/>
    <dbReference type="OrthoDB" id="2066at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010020">
        <property type="term" value="P:chloroplast fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219:SF14">
        <property type="entry name" value="PROTEIN COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="YLMG HOMOLOG PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="CCB3_YggT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="67" mass="7486" checksum="79D000F074555228" modified="2009-05-26" version="1" fragment="single">TLNIYNTLLIGRLILTWFPSPPRQIVYPLATLCDPYLNLFRGIIPPIGGTIDLSPILAFTVLNVFTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2Y3</accession>
    <name>C1N2Y3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_51962</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062513.1">
        <property type="nucleotide sequence ID" value="XM_003062467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2Y3"/>
    <dbReference type="GeneID" id="9687953"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51962"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="85" mass="9051" checksum="3D0AF165A36912EE" modified="2009-05-26" version="1">MRRGHPRRGLNNLKGYVGVSGVASPKGRRHQNNNLWGAIATAAARGGVASCVAPGPRRRVLPRILIVACLGYTVKRSKRANAPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N330</accession>
    <name>C1N330_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_68514</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062537.1">
        <property type="nucleotide sequence ID" value="XM_003062491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N330"/>
    <dbReference type="STRING" id="564608.C1N330"/>
    <dbReference type="GeneID" id="9687749"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68514"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="7729168at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186:SF38">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="5">
        <location>
            <begin position="349"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="233"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="388"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="499"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="235"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="536" mass="57736" checksum="20EF04B3010516A1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1N379</accession>
    <name>C1N379_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">S-acyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_35836</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062561.1">
        <property type="nucleotide sequence ID" value="XM_003062515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N379"/>
    <dbReference type="STRING" id="564608.C1N379"/>
    <dbReference type="GeneID" id="9688001"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35836"/>
    <dbReference type="eggNOG" id="KOG1315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RRFCKWC"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="10">
        <location>
            <begin position="151"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="372" mass="40557" checksum="818C3AFB5C247BD8" modified="2009-05-26" version="1">MSASFSSLDLMEKDALMARGGDRGRGGDDIVQKAFGGSRFRQIPRAIFAKLTLPVILVLGVIWYVYFVAVHGVMRPWVLHGANSTSTHEYAFTVTTCMAVVMYACCVFVDPGRVPAHYRPNDGDGGGPGGLNGGGSSSSRGRLLELKRKGGSRFCKKCMTHKPPRAHHCRVCNKCVLRMDHHCVWINNCVGHGNYKAFFLFLTYVAVACWHAFVCLAWHAFEGLEDDHVAAARSHGWILLEVSCLTLCVPLVVALSLLWCWHAYLVVNNKTTIEHYEGVRSRVVPRDDGEGGGGGAVNMPPLHPTGGAADAAHPYSLGVVANLREILGHRVLCWLAPSCAISGDGLSFANVADGPRYRREVKKKETELTLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3E7</accession>
    <name>C1N3E7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48551</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mo25 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062597.1">
        <property type="nucleotide sequence ID" value="XM_003062551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3E7"/>
    <dbReference type="STRING" id="564608.C1N3E7"/>
    <dbReference type="GeneID" id="9688037"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48551"/>
    <dbReference type="eggNOG" id="KOG1566">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DFFCFFR"/>
    <dbReference type="OrthoDB" id="609103at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="319" mass="35505" checksum="239D1A47BFD0923B" modified="2009-05-26" version="1">MRAIMFGETDAPPDPATQSTLASEVAKSDLLGVLIASLPSLHFETRKDAAAVFNGLMRVEPEDAPCPFVEYLERRPELLRTMTTASELAGAEADGQGGGGGDASAALTLGTMLREAVRHERLCAAVLRDAKFEKMFEYMQLPTFEIASDAAASFREILTRHKGAVATFLSEHFDGFFGKFNAMLENGNYVTRRQSLKLLSELLLDRANVGSMMRYIGSVENMCLMMNLLRDEAKSIQFEAFHVFKVFVANPNKPPAVLSILLKNREKMIGYLANFQNDREDEQFVEEKAMLMRLMEQLPQPETNYCVRVPESPTKSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3K7</accession>
    <name>C1N3K7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52210</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062631.1">
        <property type="nucleotide sequence ID" value="XM_003062585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3K7"/>
    <dbReference type="STRING" id="564608.C1N3K7"/>
    <dbReference type="GeneID" id="9688071"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52210"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014848">
        <property type="entry name" value="Rgp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12507">
        <property type="entry name" value="REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="426" mass="44783" checksum="E6C30ED501478EFB" modified="2009-05-26" version="1">MFAPAAPLRLLTLTTISHDDVVPGEDFHLTLALHAKDAAGAPRDSNLSSSASSSSATTTPPPPPPPPVAVREIRVAWHGVERLDPARVKRRDGHRRDGTGLGPGERFIARSPVGVVARDVIVPMDQTRAFRVGARLPPGIPPSYDRGGITRIKYYMSFTAIVTTERGGGPSRDGVVEHVVELPVLAADGFGESGGGVVVGEGASPPPSPSGREGGSLGLTLLDLDAARESGSVDAPRTPRVVPPASPTLAEAASLRSPPRSPLAYYARSGANGDASFDASAANHDRIPSFNITVGDERLLRVIARPPLPRVRPGDCVSGVFDLRVENEDGGEDGRRDLGGRRAPRCIRATATLESEEAVSTTAGHVAFEDAEAMGEVISIVTPWGHSDEDVRDLRESCFVLTVPKDAPVRCVLLSHAGPRTTASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3X9</accession>
    <name>C1N3X9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_9309</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062452.1">
        <property type="nucleotide sequence ID" value="XM_003062406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3X9"/>
    <dbReference type="GeneID" id="9688133"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9309"/>
    <dbReference type="eggNOG" id="KOG0713">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QAYETIG"/>
    <dbReference type="OrthoDB" id="5894at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="3"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="75" mass="8641" checksum="4B194C15EF1FCA21" modified="2009-05-26" version="1" fragment="single">DADPYKLLDLSRGAGDADIKRAHRKLSLKYHPDKQSGKTPEDVEKAQQRFMAIQRAYETLSDPERRRNYDSTGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N419</accession>
    <name>C1N419_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68795</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062468.1">
        <property type="nucleotide sequence ID" value="XM_003062422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N419"/>
    <dbReference type="GeneID" id="9688157"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68795"/>
    <dbReference type="OMA" id="AGARAEX"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="422" mass="49241" checksum="DB801C0368EE2240" modified="2009-05-26" version="1">MTFPPPARNPRRRRRRHRVQRSVLRGRGLGPAPELPERRGGGDGGGPGERGARRPEELFREPARADAAQRAVRRPHASARAFRRDQLRAAHRVRGGREPVGGRDLFLEKRHGHARYARRRSRGEEGGGRRKTESRVSRVRPRDARRGRRRESGRGDPRSRRRWKRRPRRRRHRARVRVAVRAVRRQGQSDIRSRRRARVWIRVFRLQVSERLPRPRARRRASRPSRIRRDQRERRPSFGAILREEIRHGEQRSFGREPLRAEIAAGVEAAHVRRAAGDARDPAPARGGVLRRRRVGARARRRVQGRGHRDRRRRRREGDTGGERTRRGRVRRRGDVVRRVREGRRGGRQGAADGVQLAARRQGRVIDYDTVWVCLVVGLLWIHTVSKRRVVPERTVCSRRSLTARRRPTRPGTRPSRAPLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N421</accession>
    <name>C1N421_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_52378</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062469.1">
        <property type="nucleotide sequence ID" value="XM_003062423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N421"/>
    <dbReference type="GeneID" id="9688158"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52378"/>
    <dbReference type="OrthoDB" id="7862313at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="65" mass="7117" checksum="76D062E2B1D9FEC6" modified="2009-05-26" version="1">MGNACGTPASGRERVPEPSALDALISEKVKDYTRRHPVEASKTVNQVRSIHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4F4</accession>
    <name>C1N4F4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52537</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062780.1">
        <property type="nucleotide sequence ID" value="XM_003062734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4F4"/>
    <dbReference type="GeneID" id="9688430"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52537"/>
    <dbReference type="OMA" id="CANVDIP"/>
    <dbReference type="OrthoDB" id="10460329at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="223" mass="25386" checksum="E696B05B8E5A94D8" modified="2009-05-26" version="1">MYKKNSILDRKITAPSMRNRANADAEWEAQQRADAIKFARIRANAARAGASAEFDWRDPDHMQSTTYDKTHRLQTVVSDKGLVTIPCANVDIPSGVRKIPAPWERAENYVESELLSEVPTSPMSPTSHGAFSPSSARDSHGSPKPLYRDHARMVAEDDPSDHHTELRRVLFYTLCWRCDPPRLLSGEYDPIRHEWTSPPKDAECLDREALPHGHRSLHNHYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N544</accession>
    <name>C1N544_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_66923</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062909.1">
        <property type="nucleotide sequence ID" value="XM_003062863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N544"/>
    <dbReference type="GeneID" id="9688349"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66923"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="190" mass="21778" checksum="89E773F2D18CC38F" modified="2009-05-26" version="1">MYYQSAVLPEVYTVRTVISHRPSSQVRGGVRYFVRAVPRRDPQFLPVLAPLQRARALGEPQHPPPQPLRGRRGALGTRVGTLGTQRRHLDELHAVLAAHRDDVEPVRGGDAEARRPARVFRRHRVHDPRHRVPRRVERDNLPRGRGRAEVRHARGRGGPRAEGVARFWFFRERRAARGARRERLEALKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5E8</accession>
    <name>C1N5E8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Starch synthase, chloroplastic/amyloplastic</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SSIIA</name>
        <name evidence="16" type="ORF">MICPUCDRAFT_29784</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Chloroplast</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Amyloplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063348.1">
        <property type="nucleotide sequence ID" value="XM_003063302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5E8"/>
    <dbReference type="STRING" id="564608.C1N5E8"/>
    <dbReference type="GeneID" id="9688982"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29784"/>
    <dbReference type="eggNOG" id="ENOG502QT35">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WINEEEW"/>
    <dbReference type="OrthoDB" id="512920at2759"/>
    <dbReference type="UniPathway" id="UPA00152"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009501">
        <property type="term" value="C:amyloplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010021">
        <property type="term" value="P:amylopectin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000048">
        <property type="entry name" value="Starch synthase, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45825">
        <property type="entry name" value="GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45825:SF2">
        <property type="entry name" value="STARCH SYNTHASE 2, CHLOROPLASTIC_AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0035">Amyloplast</keyword>
    <keyword evidence="4 11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0750">Starch biosynthesis</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Starch synthase catalytic" evidence="15">
        <location>
            <begin position="133"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="14">
        <location>
            <begin position="436"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="474"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH52484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="576" mass="62251" checksum="DFE52B5546C751E8" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5J8</accession>
    <name>C1N5J8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52948</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063170.1">
        <property type="nucleotide sequence ID" value="XM_003063124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5J8"/>
    <dbReference type="GeneID" id="9688815"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52948"/>
    <dbReference type="OMA" id="AREMNND"/>
    <dbReference type="OrthoDB" id="10685663at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="750"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="777"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="848" mass="88873" checksum="BF883B390B08FD18" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5T0</accession>
    <name>C1N5T0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_53026</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063418.1">
        <property type="nucleotide sequence ID" value="XM_003063372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5T0"/>
    <dbReference type="GeneID" id="9688857"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53026"/>
    <dbReference type="OMA" id="LPEHNAY"/>
    <dbReference type="OrthoDB" id="498350at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="200"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="280" mass="29629" checksum="320FCB34A3AB050B" modified="2009-05-26" version="1">MSPPPPGLNDIDAQIAALEAKLGGAVASGSSDEDADDAATRRRRERKRSEKKARKREKKEKKRRREEKESDDDDDDDDAVAAAAESDSELERIAPLPSHLLPEHNAYSGKGIGRKKKRGEKNAANAGTTTAAMTTTATRAGGDAGASGAAPAAAPTPALAAMIARREDMPRCDVCDKRFTSVAQLDEHERGKAHLKAARARATGGTPRDASRRPPGAGRPAAPGKPIAGLPGPPAGAVEHCALCRKTFTSKAQLLEHEGGKWHALRVRGELPPSRRPYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6U6</accession>
    <name>C1N6U6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_65780</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063792.1">
        <property type="nucleotide sequence ID" value="XM_003063746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6U6"/>
    <dbReference type="GeneID" id="9689057"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65780"/>
    <dbReference type="eggNOG" id="ENOG502STR6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="428841at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF10">
        <property type="entry name" value="2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="441"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="676" mass="68949" checksum="1B41365A4AB22256" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1N726</accession>
    <name>C1N726_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_44966</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063658.1">
        <property type="nucleotide sequence ID" value="XM_003063612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N726"/>
    <dbReference type="STRING" id="564608.C1N726"/>
    <dbReference type="GeneID" id="9689099"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44966"/>
    <dbReference type="eggNOG" id="KOG1051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GPMDASN"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000017">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1780.10:FF:000004">
        <property type="entry name" value="ATP-dependent Clp protease ATP-binding subunit ClpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="entry name" value="Clp, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.10">
        <property type="entry name" value="UVR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF155">
        <property type="entry name" value="CHAPERONE PROTEIN CLPC1, CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="Double Clp-N motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="12">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="11">
        <location>
            <begin position="421"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH52031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="839" mass="91911" checksum="9CD8C2A2EC70EFD6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7T9</accession>
    <name>C1N7T9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Photosystem I subunit X, chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PSAK</name>
        <name evidence="10" type="ORF">MICPUCDRAFT_53824</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PsaG/PsaK family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063968.1">
        <property type="nucleotide sequence ID" value="XM_003063922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7T9"/>
    <dbReference type="STRING" id="564608.C1N7T9"/>
    <dbReference type="GeneID" id="9689409"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53824"/>
    <dbReference type="eggNOG" id="ENOG502RZHF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VKADWSI"/>
    <dbReference type="OrthoDB" id="1904255at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.40">
        <property type="entry name" value="Chlorophyll a-b binding protein like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000549">
        <property type="entry name" value="PSI_PsaG/PsaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023618">
        <property type="entry name" value="PSI_PsaG/PsaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016370">
        <property type="entry name" value="PSI_PsaG/PsaK_pln"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34195:SF2">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT PSAK, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34195">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT V, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01241">
        <property type="entry name" value="PSI_PSAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH51590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="125" mass="13103" checksum="08F795C2D85ABB2A" modified="2009-05-26" version="1">MNALCASPVVAPQFAGAKKSFSVKKAAAVKRDVRVKADWSIGSPENAIVCINTAACLFAGRFGLAPTVNKNYGGADSYTMVEAERPRVQSRDPAGFTIVDVAAWGSLAHIISAGEILGQQAKGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Z5</accession>
    <name>C1N7Z5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_53887</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064180.1">
        <property type="nucleotide sequence ID" value="XM_003064134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Z5"/>
    <dbReference type="GeneID" id="9689434"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53887"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="228" mass="25475" checksum="1CA837103362DE94" modified="2009-05-26" version="1">MPFTDDAVPPTARRSFDSLTSSTSADAVARLTSPRLASPQAVAPVAYERSYEVVCEGLCWTALGARQYSMLRGNKVWLPLRPITMVMSMIMLRFEFSKQAKWFIFRNVVDSCGHAGRHYVEGGGGSANAYVRCLNRQIPMCVVKIVFGLAFHWWIERRDKVRFLQKYSVVDARLVAAVRERERDRDRGCADAFGEDDFFGRGLGKRVSAGAIVVAVTLYAIEHLNAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N874</accession>
    <name>C1N874_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_5948</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064032.1">
        <property type="nucleotide sequence ID" value="XM_003063986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N874"/>
    <dbReference type="STRING" id="564608.C1N874"/>
    <dbReference type="GeneID" id="9689661"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5948"/>
    <dbReference type="eggNOG" id="KOG3996">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NEESWKH"/>
    <dbReference type="OrthoDB" id="4243at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF8">
        <property type="entry name" value="PROTEIN HRI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00821">
        <property type="entry name" value="CYTO_HEME_LYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH51654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="187" mass="21283" checksum="F6FFBE96B26CBE19" modified="2009-05-26" version="1" fragment="single">IDPRNNMPVAASQSMAPGQRRKISTERQRSTIPKSGVSSAEASTWTYPSPQMFYNSLVRKGKATDCTEDDMESVVSVHNAMNEDTWRRVVAWERLHVHECRDPMLLRFLGRPDDLSPLAWARYLTGGGKPFDRHDWYVDRCGQQVRYVIDYYFHEDKAGTPGQFDLVVRPAADSVGAVADRVKMAIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1N937</accession>
    <name>C1N937_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyltransferase</fullName>
            <ecNumber evidence="14">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_43472</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="14"/>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064386.1">
        <property type="nucleotide sequence ID" value="XM_003064340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N937"/>
    <dbReference type="STRING" id="564608.C1N937"/>
    <dbReference type="GeneID" id="9689991"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43472"/>
    <dbReference type="eggNOG" id="KOG0831">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DEHKESC"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH51291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="356" mass="39725" checksum="F16EB468E048C12B" modified="2009-05-26" version="1">MALARVNALFVDRIERLGLVRVSRTPSSDGDAAASPSPSGSRRSDAPCASNDESGADDGDYLEINFAPTPPWTLWNLAQTTWGFLLAHYIFYGFVASALACAFIELTAVKAALAVGLVLYQKSFWDGSELRSGRPWHAFRAHPVWNLTQSYFPARLIRTRALDASEKYVFGWHPHVPGCREICLWMGAVDAGRTTASRVLDDDCSVAVYPGGSREIFSTDPNSSETKVYLSKRRGFVKLAIAHGAALVPVFVFGEKRCYRRLNVPAPLRDWLLRTWKIPLIVFWGRWFTWYPYAARQTVVFGAPIDTKKHKPPAGEDPSEARVDEVHAEYVEAVRALFQAHKRDAGYGEEETLTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9W2</accession>
    <name>C1N9W2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54663</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064802.1">
        <property type="nucleotide sequence ID" value="XM_003064756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9W2"/>
    <dbReference type="GeneID" id="9690243"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54663"/>
    <dbReference type="OrthoDB" id="541883at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="136" mass="14974" checksum="748E4A564607C23A" modified="2009-05-26" version="1">MPFNSDSDAFQLHPDRRRSSGWRKATILADCVVHLCAPRGHPAAVNGAQLIDDEYLRDIGATDEDLIEYRCDPAVEPPRLLAPGAEEGGHGASHLTLVPIRPRRRGERRSLRTLPSSLSADPSVSIPVLDAFQLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAA3</accession>
    <name>C1NAA3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_43728</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.</text>
    </comment>
    <comment type="function">
        <text evidence="6">This protein binds RuBisCO small and large subunits and is implicated in the assembly of the enzyme oligomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Oligomer of probably six alpha and six beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064760.1">
        <property type="nucleotide sequence ID" value="XM_003064714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAA3"/>
    <dbReference type="STRING" id="564608.C1NAA3"/>
    <dbReference type="GeneID" id="9690310"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43728"/>
    <dbReference type="eggNOG" id="KOG0356">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TDTDKME"/>
    <dbReference type="OrthoDB" id="1733909at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009488">
        <property type="entry name" value="PRK12850.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009489">
        <property type="entry name" value="PRK12851.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00058559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00062746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH51094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="544" mass="57195" checksum="1B6E7B60F26155BD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH44</accession>
    <name>C1MH44_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Ribonuclease</fullName>
            <ecNumber evidence="13">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">RNHB</name>
        <name evidence="16" type="ORF">MICPUCDRAFT_50045</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 13">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="12">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">Belongs to the RNase HII family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="13"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054888.1">
        <property type="nucleotide sequence ID" value="XM_003054842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH44"/>
    <dbReference type="STRING" id="564608.C1MH44"/>
    <dbReference type="GeneID" id="9681092"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50045"/>
    <dbReference type="eggNOG" id="KOG2299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YPTKLHL"/>
    <dbReference type="OrthoDB" id="7462577at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000006">
        <property type="entry name" value="Ribonuclease HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000594">
        <property type="entry name" value="PRK00015.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000595">
        <property type="entry name" value="PRK00015.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF23">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51975">
        <property type="entry name" value="RNASE_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12 13" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12 13" id="KW-0540">Nuclease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-2" evidence="15">
        <location>
            <begin position="60"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH60140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="256" mass="28085" checksum="62190A1A36DC00E9" modified="2009-05-26" version="1">MADAPFEPPPKQSPSSRSSTRKRTTKAEKDAELAKKAAKKPKKNGPSRAHEQMYWDQGKKIVCGVDEAGRGPLAGPVVAAACVFPEDLVIDAINDSKQMTEEDREEVYEQLMENPEVLKSVCVIDHKEIDDINILEATMKAMRKSVEGLPTKADWVLVDGNRVPEPLKGRAEAIVKGDAKSVCIAAASVLAKVTRDRMMVEIAKEHPEYGFAEHKGYGVKSHMAAIHEHGPCPYHRMTFAPMKYMPGGSAYDGDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIH4</accession>
    <name>C1MIH4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">H(+)-transporting two-sector ATPase</fullName>
            <ecNumber evidence="4">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_43849</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="4"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055132.1">
        <property type="nucleotide sequence ID" value="XM_003055086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIH4"/>
    <dbReference type="STRING" id="564608.C1MIH4"/>
    <dbReference type="GeneID" id="9680703"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43849"/>
    <dbReference type="eggNOG" id="KOG1352">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RIVKTFW"/>
    <dbReference type="OrthoDB" id="1676488at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000325">
        <property type="term" value="C:plant-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18111">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18119">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01134">
        <property type="entry name" value="V_A-ATPase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000002">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000002">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000008">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000052">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00309">
        <property type="entry name" value="ATP_synth_A_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031686">
        <property type="entry name" value="ATP-synth_a_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005725">
        <property type="entry name" value="ATPase_V1-cplx_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022878">
        <property type="entry name" value="V-ATPase_asu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003220">
        <property type="entry name" value="PRK04192.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01042">
        <property type="entry name" value="V-ATPase_V1_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607:SF1">
        <property type="entry name" value="H(+)-TRANSPORTING TWO-SECTOR ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607">
        <property type="entry name" value="V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16886">
        <property type="entry name" value="ATP-synt_ab_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="13">
        <location>
            <begin position="16"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="ATPsynthase alpha/beta subunit barrel-sandwich" evidence="14">
        <location>
            <begin position="118"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="12">
        <location>
            <begin position="235"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="15">
        <location>
            <begin position="469"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH60384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="638" mass="68831" checksum="41772C0EBEA568C5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ30</accession>
    <name>C1MJ30_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_38224</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055240.1">
        <property type="nucleotide sequence ID" value="XM_003055194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ30"/>
    <dbReference type="GeneID" id="9680400"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38224"/>
    <dbReference type="OMA" id="QKWASKE"/>
    <dbReference type="OrthoDB" id="496367at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="149" mass="16299" checksum="9DC3D9083DADDDD7" modified="2009-05-26" version="1">MSAHTLAGVAPCSVRAPSSRTTPRRGRRAASVATRAGGKPGENGEPYVATNVFVVPDGDAAVVKRLKDEMASRQTAMKAAPGFVSCDFHPGPGVNEHTFKQQWSTKQAYEDYMNTPERRRSHLAAGVYQYLPKDKWSVPENFTPLLPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ34</accession>
    <name>C1MJ34_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_12462</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit transport protein particle (TRAPP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055765.1">
        <property type="nucleotide sequence ID" value="XM_003055719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ34"/>
    <dbReference type="STRING" id="564608.C1MJ34"/>
    <dbReference type="GeneID" id="9680307"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12462"/>
    <dbReference type="eggNOG" id="KOG3369">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MPIRTEG"/>
    <dbReference type="OrthoDB" id="246406at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14856">
        <property type="entry name" value="TRAPPC4_synbindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007233">
        <property type="entry name" value="TRAPPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249:SF15">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04099">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01399">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="5 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH61017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="156" mass="17071" checksum="2FA6CCC18495E558" modified="2009-05-26" version="1">MSAPPTPATLPEEPENPPGVHSVWIINKSGGLVFRDVYADIAPIDTNETLRLASMWHSMHAIAAQLGPELRGELPSETDGFHLHCAQTPTGTKLMLTCAPGTFADHDAGQAVLRTVRDLYADYVMKNPFYEAEMPIRCELFEKRLRDAIDAVNGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJB4</accession>
    <name>C1MJB4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_50878</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055803.1">
        <property type="nucleotide sequence ID" value="XM_003055757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJB4"/>
    <dbReference type="STRING" id="564608.C1MJB4"/>
    <dbReference type="GeneID" id="9680807"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50878"/>
    <dbReference type="eggNOG" id="KOG0817">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YSGEHKM"/>
    <dbReference type="OrthoDB" id="548600at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF15">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="56"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH61055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="178" mass="18538" checksum="44F0F0622510FE99" modified="2009-05-26" version="1">MGGQKKPAKKKKSSSSGGAKVSSQTPVFGSIEDGDAEEFAECLARTPQCVHETNKNGWTPAHQAAFSGEVEMLKTLIARGAAVDKRDHDGDTPVHYAAAQGEMDCIRALADAGCALELKDNDGETPVDVASKAVKKDLKALIKERAERAEKKGEEEGVGGDGGVEEAAATLAAASIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJC6</accession>
    <name>C1MJC6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_43884</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 12">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055809.1">
        <property type="nucleotide sequence ID" value="XM_003055763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJC6"/>
    <dbReference type="STRING" id="564608.C1MJC6"/>
    <dbReference type="GeneID" id="9680490"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43884"/>
    <dbReference type="eggNOG" id="KOG2906">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TISFECI"/>
    <dbReference type="OrthoDB" id="282152at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10509">
        <property type="entry name" value="Zn-ribbon_RPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034014">
        <property type="entry name" value="Zn_ribbon_RPC11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF12">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6 8 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002911946" description="DNA-directed RNA polymerase subunit" evidence="13">
        <location>
            <begin position="24"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="14">
        <location>
            <begin position="71"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="10">
        <location>
            <begin position="5"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH61061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="113" mass="12450" checksum="25C33DD8A4C87BD8" modified="2009-05-26" version="1">MLTFCPSCANMLLVTTNAAGADASPCLKLICQTCPYAYDVTKTLRDDVPVTRKEVDDVLGGDDAWKNVDKTAATCPKCDHGQAYFMQIQIRSADEPMSTFFKCVKCGNQWREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJQ7</accession>
    <name>C1MJQ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55058</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056254.1">
        <property type="nucleotide sequence ID" value="XM_003056208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJQ7"/>
    <dbReference type="GeneID" id="9681883"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55058"/>
    <dbReference type="OrthoDB" id="10258130at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="65" mass="7293" checksum="920F6C338FF7A64A" modified="2009-05-26" version="1">MDRPMKLRHAHSIDPPPPRTHRLLGEGVTSPPETSKRVLVPLCGKARSYLHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJR1</accession>
    <name>C1MJR1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_55062</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056255.1">
        <property type="nucleotide sequence ID" value="XM_003056209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJR1"/>
    <dbReference type="GeneID" id="9681281"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55062"/>
    <dbReference type="eggNOG" id="KOG1850">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IYGEYSK"/>
    <dbReference type="OrthoDB" id="425555at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="120"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="346"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="507" mass="56345" checksum="1CEB4D78779A9895" modified="2009-05-26" version="1">MAAKGKAKGKGKAPSAADADADATDRPTATEPTAAKETDLEDETPPPIKRTALEDADAIVADAALTDAQKLDAMRALLLDRDAAHDARAKKLRTRESRALAAAGVVAVERDAARDELGKALHLKDKLEALCRELQKTNKAVVDGAKIAAEEESKRREELSAKFEGGLTDIRCVHSTLVPIRPRRRDERHSLRTFAGVSLRPGSLAFNPRLRYLSTHPDAFQLHPDVALYEMALSAKLEAHGAERDAQTKENATLRGHLESLMQRAEAQQARPGSHWFPYDRVRVVKAVSLGPLPSFLSAHPALLSIPTRRDAFRLRRLTPFIDSAPTSLASYILWNGPQKHFEKAKEAFELEKRLYEARLEESNERLRAMEAHAEELRGTCVAAGKREKEALAQLVEYGERFATFQDTIKQSSETFESFRVDIKDLRKRLEKSEKEKREMEVKTAKSDVVLIETTQEREEWRRHAEAYKLKAGKLEALCRTLSKRAGAEEEGGGLAADGKENDAVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJS8</accession>
    <name>C1MJS8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55080</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056265.1">
        <property type="nucleotide sequence ID" value="XM_003056219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJS8"/>
    <dbReference type="GeneID" id="9681890"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55080"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="228" mass="24831" checksum="25D740F07B6F6071" modified="2009-05-26" version="1">MRPRRRGERRSLRTFLPGVSLRPSLAFDPRHRRLSTPLLTPFNSNAKRYELTAAGAIDIASAVTVDLDAAGFLAIDSTTTSKLVLAPHALGRDGDTLYSYAFAIDVSDANGAAKASIDLRRNVSPVAGMVAALPVKGVAAQTTFAIAVGDGSLDPDGHLPLMIRFTALVKGAPAYQSRLLQDYRRVPSAHLRVQMFFTRPSHSLFIKVPVALHVQYERFQHLIETPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK20</accession>
    <name>C1MK20_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_55186</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055914.1">
        <property type="nucleotide sequence ID" value="XM_003055868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK20"/>
    <dbReference type="STRING" id="564608.C1MK20"/>
    <dbReference type="GeneID" id="9681455"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55186"/>
    <dbReference type="eggNOG" id="KOG1245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1903104at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF52">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="125"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="183"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH59290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="803" mass="88860" checksum="29CF8666BAF995C7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK33</accession>
    <name>C1MK33_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64189</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056320.1">
        <property type="nucleotide sequence ID" value="XM_003056274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK33"/>
    <dbReference type="GeneID" id="9681665"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64189"/>
    <dbReference type="eggNOG" id="ENOG502RYNN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10657066at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053827">
        <property type="entry name" value="Gp10_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21939">
        <property type="entry name" value="Gp10_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88874">
        <property type="entry name" value="Receptor-binding domain of short tail fibre protein gp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Baseplate structural protein Gp10 C-terminal" evidence="1">
        <location>
            <begin position="48"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="182" mass="19559" checksum="DAA64F9C580B99D9" modified="2009-05-26" version="1">MSFVQALSSARRNQVISAMKTTSSGAIEMTGDIQITGALEAQSIGTTLLNTIFPIGSIYFTASAVNPSTSNGGTWQRYAQGKCLFSVDDTDTDFSFETTGGVKEVVLTEAQMPSHSHTLDDFVRAVQTNGAIYHNDFQKVPKPIGITTLANTTDTAGGLNGTTQPFNNMPPYIAIYCWKRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK71</accession>
    <name>C1MK71_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">HlyC/CorC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_31333</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055948.1">
        <property type="nucleotide sequence ID" value="XM_003055902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK71"/>
    <dbReference type="STRING" id="564608.C1MK71"/>
    <dbReference type="GeneID" id="9681926"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31333"/>
    <dbReference type="eggNOG" id="KOG2118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KLMFMHA"/>
    <dbReference type="OrthoDB" id="5353557at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010960">
        <property type="term" value="P:magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045095">
        <property type="entry name" value="ACDP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064">
        <property type="entry name" value="METAL TRANSPORTER CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064:SF94">
        <property type="entry name" value="UNEXTENDED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25562">
        <property type="entry name" value="CNBH_CNNM2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="176"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="395"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH59324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="498" mass="54577" checksum="FCEA47B48D7AF207" modified="2009-05-26" version="1">MSLDMVSLEILAEGGDEQEREYAKKIIPIRSKGNLLLCTLLLGNTMVNALIAILMANLTDGLVGLALSTLSIVVVGEIIPQAACSRHGLFIGANTVWIVKIFIVLMYVVAWPISMILDRVLGRDIGQVYSAAELNKLIRIHVENPDAQEESGLNREDGNLLTGALEYKDKKVADVMTTLDKVFMVESHTRLTFQVLIDIYKSGFTRIPVYENDRQNIVGILFTKDLILIDPDDEVEIAAVISFHGNREGGFVRGVPDNTSLDKVFREFKSSFLHLLVAYGEIGNDSDIKLDVTGVISLEDVLEAVIKDEIVDETDNFVDVNKTETVVRGRGNNQRPDPTNFLTLNELVASGSQAMTRSARSLPTSAGGISAGLEGFSVCLEDGCNTDEIPELPPLYRKGSSCDYFTLILQGKVLVHAGSDDFVSELGPWCYIGQKALVSDVFIPDFRATPQGSCRLLYIRRGDYKSALRAAQVEAMSGSRSLLGSRHTLVADSEPDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK79</accession>
    <name>C1MK79_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_46519</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055951.1">
        <property type="nucleotide sequence ID" value="XM_003055905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK79"/>
    <dbReference type="GeneID" id="9681673"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46519"/>
    <dbReference type="eggNOG" id="ENOG502QU5X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CPGQWSF"/>
    <dbReference type="OrthoDB" id="421671at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF2">
        <property type="entry name" value="LYSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="430" mass="47148" checksum="9760FB9278815A1C" modified="2009-05-26" version="1">MTPPRGTGAGDASKGRAYLIAPPPLFPLVPAFSRETFRYEIIPNSMWFFEQKQGIGLGLNVSVNVRMTVIKLESGGLWVHAPVAPTKECVALLNELDAPVEHIVLPTTLFEHKIFVGPFQRKYPDAEVWIAPDQWSWPVNLPPTFFGIFKTGTLGFGGGVDANGDAPSWADEFECELLTPPALGVASYVAFTECAFLHKATRTLLVTDAVVYVSENVPDAIPDRDLLESGDDDNFTIAALKFLNLFDIKTKAKTRTTSSKDMTENERKRLGWQRNALQALYFGPSNLLDPEMSWVGIVNRLIVAPVVSTLVYENVPDDVADWARRIGRWKFDTIVPAHFDAPIKAGPKEWNAAFGFLPTSRPADEPEITGGVGGGVRGFGDGYYPDEDMILLRGVGDVLKDAGVIFTDENRPRRKLGVVQGAGVGGEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML38</accession>
    <name>C1ML38_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_64798</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056106.1">
        <property type="nucleotide sequence ID" value="XM_003056060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML38"/>
    <dbReference type="STRING" id="564608.C1ML38"/>
    <dbReference type="GeneID" id="9681555"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64798"/>
    <dbReference type="eggNOG" id="KOG1963">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WERRENI"/>
    <dbReference type="OrthoDB" id="498846at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000234">
        <property type="term" value="P:positive regulation of rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053826">
        <property type="entry name" value="WDR75"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23869">
        <property type="entry name" value="Beta-prop_WDR75_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="171"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="258"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="627" mass="68385" checksum="80E6368BB82EE7B5" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML51</accession>
    <name>C1ML51_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">methionine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Methionyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_49468</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="1"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056114.1">
        <property type="nucleotide sequence ID" value="XM_003056068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML51"/>
    <dbReference type="STRING" id="564608.C1ML51"/>
    <dbReference type="GeneID" id="9682003"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49468"/>
    <dbReference type="eggNOG" id="KOG0436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NMFLPDR"/>
    <dbReference type="OrthoDB" id="24670at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.220.10:FF:000002">
        <property type="entry name" value="Methionine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="METHIONYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="64"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="201"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="600" mass="67856" checksum="B13AD1E35406C5FC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLD7</accession>
    <name>C1MLD7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methenyltetrahydrofolate cyclohydrolase</fullName>
            <ecNumber evidence="2">3.5.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FOLD</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_55677</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.9" evidence="2"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056547.1">
        <property type="nucleotide sequence ID" value="XM_003056501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLD7"/>
    <dbReference type="STRING" id="564608.C1MLD7"/>
    <dbReference type="GeneID" id="9681830"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55677"/>
    <dbReference type="eggNOG" id="KOG0089">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IHPGKDV"/>
    <dbReference type="OrthoDB" id="5126881at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000005">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF27">
        <property type="entry name" value="BIFUNCTIONAL PROTEIN FOLD 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="7">
        <location>
            <begin position="59"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="8">
        <location>
            <begin position="192"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="8">
        <location>
            <begin position="275"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="8">
        <location>
            <begin position="357"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="405" mass="44191" checksum="BE696F80DB3DBC1F" modified="2009-05-26" version="1">MRLFGLRPVLSRGSCLEGFVHCISKRSLNNFDACRFGHTSLGIVSEICAKPWTGGARHLDGRQHAIRWMREIAISASRNPRPPGLAAIVVGNRPDSLLYVRRKGEACKKTGIHFYLIHLPGDIRQGKVRQILRRLNSDKNIDGILVQLPMPPQITENKLLECISPEKDVDGLHPKNVGRLSARGTWRPVFMPCAPLGCMELLWREKINVKKKAVTVIGDSNIVGMPLSWLLRDAGASSVTILHSRAIWFLDKFSTAGSDDSQLCEDKPLQAQILHSLCEADVVIAAVGSVGLVKREWIKEGATVVDIGINAVPDCHESVIFTGISPQKDCVNVCSSVTAMQRDAQQSFRSVPQPLRNFKILGDVAAEEVSHVAGAMTSVPGGAGPMTIAALLSNTCLSASRKHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLF2</accession>
    <name>C1MLF2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="3 13">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">HEMB</name>
        <name evidence="16" type="ORF">MICPUCDRAFT_45299</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the ALAD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="3 13"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056156.1">
        <property type="nucleotide sequence ID" value="XM_003056110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLF2"/>
    <dbReference type="STRING" id="564608.C1MLF2"/>
    <dbReference type="GeneID" id="9682031"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45299"/>
    <dbReference type="eggNOG" id="KOG2794">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YMDIIWR"/>
    <dbReference type="OrthoDB" id="1530at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04823">
        <property type="entry name" value="ALAD_PBGS_aspartate_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000019">
        <property type="entry name" value="Delta-aminolevulinic acid dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006762">
        <property type="entry name" value="PRK09283.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458:SF0">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="5" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 13 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="25"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="11">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="11">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH59532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="388" mass="42429" checksum="775BCE750664BF2E" modified="2009-05-26" version="1">MSRVASPCSPRIPIRLKFNTLVRASSAKSDASLAPPTTRKPAKVPEGTPVIPPQDLASRPRRNRRSSTVRDAFRETILTPSNFIYPIFVHDGDDDIPIGSMPGQSRLGWKTGMINKVREARAAGVNQVVVFPKTPDNLKTPTAEECYNPNGLAQRSISLLKDTFPDLEVYTDVALDPYNTMGHDGMVRSDGVIMNDETVYYLCKQAVSQARAGADVISPSDMMDGRVGAIREALDSEGFTNVAIMSYTAKYNSAYYGPFRDALASAPRPGNEDWKIPLDKAEYQMDPANFRECLREAALDEAEGADILMVKPAGAYLDIIRALKDSTTLPISAYQVSGEYSMLKAAAAAGYLNEEEAVLESLISIKRAGADLTLTYYAVDAAKWIQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLN6</accession>
    <name>C1MLN6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_14275</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056598.1">
        <property type="nucleotide sequence ID" value="XM_003056552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLN6"/>
    <dbReference type="STRING" id="564608.C1MLN6"/>
    <dbReference type="GeneID" id="9682052"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14275"/>
    <dbReference type="eggNOG" id="KOG0937">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KPLIWCD"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09250">
        <property type="entry name" value="AP-1_Mu1_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14835">
        <property type="entry name" value="AP1_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="6">
        <location>
            <begin position="174"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="438" mass="49696" checksum="F54286146C680679" modified="2009-05-26" version="1">MTSPAVCSVLHILDGNMKKLLSRDWRGDISPACIDRFVARVWQTLYAESESELKPVMYDSDAEVSYVYITHNNLYLLAITKSNCNAAALLTFLHRLVDIFRHYFKTLEESIRDNFVIIYELLDEVMDNGYPQFTEAKILSEFITVGAHQLIAPKAPMAVTNAVSWRSEGIRYQKNEVFLDVVESLNIVVNAAGQVVNSETFGALRLRAYLSGMPECKLGLNDKIMLHAQNRSTKGKSVELDDIKFHQCVRLARFENDRTISFIPPDGHFDLMNYRISTANVKPLIWIEASVNRPSRSRVEYVVKVRTHFKSRLQATGVEIKLPVSSDATSPEVNTGLGSVAYVPEQEAMLWKIKSVQGGKEIMMRAKFSLPSVSALEDDGPVQKKPPITCKFEIPYYTVSGVQVRYLKVLERSGYQALPWVRYITKSGNYEFRLDHGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLW2</accession>
    <name>C1MLW2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">RNA cytidine acetyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">18S rRNA cytosine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_56289</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51424"/>
            <dbReference type="Rhea" id="RHEA-COMP:13575"/>
            <dbReference type="Rhea" id="RHEA-COMP:13576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a cytidine in tRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in tRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53876"/>
            <dbReference type="Rhea" id="RHEA-COMP:13670"/>
            <dbReference type="Rhea" id="RHEA-COMP:13671"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="11"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056834.1">
        <property type="nucleotide sequence ID" value="XM_003056788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLW2"/>
    <dbReference type="STRING" id="564608.C1MLW2"/>
    <dbReference type="GeneID" id="9682728"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56289"/>
    <dbReference type="eggNOG" id="KOG2036">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HLHYIMS"/>
    <dbReference type="OrthoDB" id="10067491at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990883">
        <property type="term" value="F:18S rRNA cytidine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051392">
        <property type="term" value="F:tRNA cytidine N4-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904812">
        <property type="term" value="P:rRNA acetylation involved in maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051391">
        <property type="term" value="P:tRNA acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11040:FF:000002">
        <property type="entry name" value="RNA cytidine acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002218">
        <property type="entry name" value="tRNA(Met) cytidine acetyltransferase TmcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03211">
        <property type="entry name" value="RNA_acetyltr_Nat10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033688">
        <property type="entry name" value="NAT10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007807">
        <property type="entry name" value="TcmA/NAT10_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032672">
        <property type="entry name" value="TmcA/NAT10/Kre33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013562">
        <property type="entry name" value="TmcA/NAT10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027992">
        <property type="entry name" value="tRNA_bind_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925">
        <property type="entry name" value="N-ACETYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925:SF5">
        <property type="entry name" value="RNA CYTIDINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13718">
        <property type="entry name" value="GNAT_acetyltr_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05127">
        <property type="entry name" value="NAT10_TcmA_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08351">
        <property type="entry name" value="TmcA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13725">
        <property type="entry name" value="tRNA_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TmcA/NAT10 N-terminal" evidence="13">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="TcmA/NAT10 helicase" evidence="12">
        <location>
            <begin position="278"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="14">
        <location>
            <begin position="521"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="Possible tRNA binding" evidence="15">
        <location>
            <begin position="764"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="622"/>
            <end position="624"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="721"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF13725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH58479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="993" mass="108517" checksum="F30BDE5A6F334E5E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM82</accession>
    <name>C1MM82_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56432</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057354.1">
        <property type="nucleotide sequence ID" value="XM_003057308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM82"/>
    <dbReference type="GeneID" id="9682328"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56432"/>
    <dbReference type="OMA" id="PQERSSC"/>
    <dbReference type="OrthoDB" id="10635045at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="208"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="397"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="284"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="426" mass="44583" checksum="848A85C63D8836C9" modified="2009-05-26" version="1">MRPLPVASARATISGRSVRALDAPRRRALRRVVAASAAAAAKRARRSQPSVDPPPARAGAAAPSPSSPSADHLSKTALGSCALLAMCAVVEPASARDVTVSLPDLPDFGEVSTSLRVALDGLSNLEVPSTRMEFLRLVLSNPIAAVAVSVSAYLVIPKASELLVKFVLAPAIVLVVAAAAAQHPAETSAVAAAAIREVRDNPTVTSGVILALCVVFLSPYFLVAGFAAIIVSGVNVLPDALKPALPRPLRDATNQIAALQRAADPSVKRVQGFSDEAYRRSMEVKSEMERLAAEEAERDRAEAIRRRAETVASGVTSAITAPAREAERRVRDAAEIAADAASDAADVVRDVNAEATSVTRCVDKPTAASRAACVDENRAERTAREAKRTEALRAKARRLRANSAKATPPIPPPPDVLGALTRTTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMF1</accession>
    <name>C1MMF1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56506</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056918.1">
        <property type="nucleotide sequence ID" value="XM_003056872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMF1"/>
    <dbReference type="GeneID" id="9682833"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56506"/>
    <dbReference type="OMA" id="MRTSNEN"/>
    <dbReference type="OrthoDB" id="10549062at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="157" mass="16940" checksum="D40F08915833BC63" modified="2009-05-26" version="1">MQTEDEDADVETGLDTDAEMAVGESLRRRRGNKEKRSAVGRRKKSSLGANGASGGGGGGGSSSKKHSKRRARRHSMPAFTLSDADGDETKWERLNRRLDAMRLLPRGSRYASQQIDLISKALAILRKTRASDGGGGGVERTNDENDELARLLSAVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN64</accession>
    <name>C1MN64_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_56797</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057526.1">
        <property type="nucleotide sequence ID" value="XM_003057480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN64"/>
    <dbReference type="GeneID" id="9682488"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56797"/>
    <dbReference type="OrthoDB" id="10267210at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00227">
        <property type="entry name" value="RNase_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992:SF1">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="30"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="288"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="46"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="344" mass="37577" checksum="397C844DFABEE2AB" modified="2009-05-26" version="1">MIRRPPLIIASSAAANARAAAFSTLTTSHRRATARAAPRAARRDALATSSSTTTTRAVARSSAPRWSSSSSSPTTTETRACFRCHAPGHLARDCPKATSASAPTSWDDDDDAADPLAYLGDIAWSDARRKEAHKASVKEGQRRAREKRAREKVESIAGEVFRPRERLKTQADFTRVQNTGRSFNGKLVRIKWCDTTDVPDVDNTRLGIKAPKKLLRRAVDRNSVKRRVRDIFRKNKEAWPSTCDMLVFCGEDALRAPYADVKAEMLYWGTNYAPKVAAQSAANRARKEAKVAAQSASSRGESRGAVRARKGGRGGRGPGRGGRGGRGRGKPEPEDDDDDDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN92</accession>
    <name>C1MN92_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40028</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_56829</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057066.1">
        <property type="nucleotide sequence ID" value="XM_003057020.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059356.1">
        <property type="nucleotide sequence ID" value="XM_003059310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN92"/>
    <dbReference type="GeneID" id="9682505"/>
    <dbReference type="GeneID" id="9684541"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40028"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56829"/>
    <dbReference type="eggNOG" id="ENOG502QRDU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PKPLWRE"/>
    <dbReference type="OrthoDB" id="272750at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1740.10">
        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="AlgH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31984:SF17">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31984">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (DUF179)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143456">
        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="363" mass="38943" checksum="6CBD799C921C2D30" modified="2009-05-26" version="1">MSFTLCASMHATRASASSSSAPARSFRARAARAERNAAHVSTSSKASSRASCPSLRAPRPAARRRAAIALRAAKDDAPKNEDDTKKEPEPEPSAASSSEDAEKLPTPEDDVAPALEGDWRDFRAKLVNSESAGSDAPGASADEAARVEAASGENIKLLSTQNPELASETPWAHVIGAPEKGCLLLASEEEFKLGQQYFHQAVILVLEHHEKGSMGVILNRPTQYNMGYVGGDDSSPFANNQLYFGGDVGDGTVSFLHGSSEVAGGSEVLPGVYLGGYDSACELVKDGTLKPTDFKFFARYCGWAPGQLESECERGVWYPVACSRQLALKQVIQLPKPLWREVMELCGGELRQTSKRSYGEEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNG2</accession>
    <name>C1MNG2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_55884</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BUD31 (G10) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056645.1">
        <property type="nucleotide sequence ID" value="XM_003056599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNG2"/>
    <dbReference type="STRING" id="564608.C1MNG2"/>
    <dbReference type="GeneID" id="9682539"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55884"/>
    <dbReference type="eggNOG" id="KOG3404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAPSASC"/>
    <dbReference type="OrthoDB" id="277109at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001748">
        <property type="entry name" value="BUD31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411:SF0">
        <property type="entry name" value="PROTEIN BUD31 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411">
        <property type="entry name" value="PROTEIN BUD31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01125">
        <property type="entry name" value="BUD31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00322">
        <property type="entry name" value="G10"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="241" mass="27361" checksum="36ED2CB8D5371D8E" modified="2009-05-26" version="1">MSFRRRLKNKKPPAGWDLIESSIEDFEQQMRDAVGEEHEGKRKNELTWRIHRIHWEKNRFIFDLRYKKNVLSDELYNYLCREKVADQPLISKWRKPGYENLCSLLSIQKGDTNFGTASICRVPMASRAPQQQARSIHWTLSPGASLRPPLAFNPRPRRLSTPTDAYELHPQLTPNVRTGCISCTSGDGAHGGPIWWNTPITAEITGKMSKGGGKKRAAEDGIEDPEVRKRLAALKGAEGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP48</accession>
    <name>C1MP48_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_25591</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057221.1">
        <property type="nucleotide sequence ID" value="XM_003057175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP48"/>
    <dbReference type="STRING" id="564608.C1MP48"/>
    <dbReference type="GeneID" id="9682199"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25591"/>
    <dbReference type="eggNOG" id="KOG0058">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MYTGHTL"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010044">
        <property type="term" value="P:response to aluminum ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18780">
        <property type="entry name" value="ABC_6TM_AtABCB27_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000058">
        <property type="entry name" value="ABC transporter B family member 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000836">
        <property type="entry name" value="ABC transporter B family member 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="21"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="343"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="606" mass="65776" checksum="BCE42D3EF3C2D9A8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPE2</accession>
    <name>C1MPE2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_25650</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056807.1">
        <property type="nucleotide sequence ID" value="XM_003056761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPE2"/>
    <dbReference type="STRING" id="564608.C1MPE2"/>
    <dbReference type="GeneID" id="9682246"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25650"/>
    <dbReference type="eggNOG" id="KOG0964">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GQKTVCA"/>
    <dbReference type="OrthoDB" id="431497at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03272">
        <property type="entry name" value="ABC_SMC3_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000424">
        <property type="entry name" value="Structural maintenance of chromosomes 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041741">
        <property type="entry name" value="SMC3_ABC_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="11">
        <location>
            <begin position="521"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="462"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1049"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1201"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="178"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="668"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="793"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="890"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1203"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1226"/>
            <end position="1262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1262" mass="141629" checksum="8E273B410A805C56" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPU7</accession>
    <name>C1MPU7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57042</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057647.1">
        <property type="nucleotide sequence ID" value="XM_003057601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPU7"/>
    <dbReference type="GeneID" id="9683019"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57042"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="101" mass="10260" checksum="D3CA705821C4FC38" modified="2009-05-26" version="1">MEAFAREKAAMEEEMSRMRGGGGGGGGGGGRGASNPSSPSTAQIDAAAVAAAAAALAAREAAVERRERELEETIAARVKAAVDDALKRAERAPRSERYGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ01</accession>
    <name>C1MQ01_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_2004</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol polyphosphate 5-phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057674.1">
        <property type="nucleotide sequence ID" value="XM_003057628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ01"/>
    <dbReference type="STRING" id="564608.C1MQ01"/>
    <dbReference type="GeneID" id="9683477"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2004"/>
    <dbReference type="eggNOG" id="KOG0565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WVKSEVR"/>
    <dbReference type="OrthoDB" id="62798at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004445">
        <property type="term" value="F:inositol-polyphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034485">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045849">
        <property type="entry name" value="IP5P_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45666:SF22">
        <property type="entry name" value="TYPE I INOSITOL POLYPHOSPHATE 5-PHOSPHATASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45666">
        <property type="entry name" value="TYPE IV INOSITOL POLYPHOSPHATE 5-PHOSPHATASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="430" mass="45998" checksum="2EF321F3811798CE" modified="2009-05-26" version="1" fragment="single">MDEPIAGYTSARDLKVLCGTWNTNGKSPPADLDVSRWLDASSRPDVVVVGFQEIVPLTAGKVLAVEDDKATREWEAIIERALNDAATTATTTAAAAAAPKNAAAFASDTSWQRAGQPPRTQTPQSAAGWTSFDSPGVSGGGGGWTSFDAPAFPGAAAAAAGRDRYIRLASKQLVGVYITVYVNASTAEHTRDVRVHTVSTGFNIGLNLGGFKTPDITLGNKGGAAVWMRVYSTPIVFICSHLSAGSKEGDAEKRSADFGEIVTKLSFPAPPSASSDGVAEKPAGVADAHAAVWLGDLNYRLNLPDDRVRAAIASGNCASLLGSDQLLLERAAGKAFVGWIEAPVTFPPTYKYRPGTNTAKEEKKKRTPAWCDRILWRGRDIRQNSYARAELTQSDHKPVLAEFTIVARELQPERLQETLDSLRRRLDAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ45</accession>
    <name>C1MQ45_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_46999</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase A22B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058062.1">
        <property type="nucleotide sequence ID" value="XM_003058016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ45"/>
    <dbReference type="GeneID" id="9683006"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46999"/>
    <dbReference type="eggNOG" id="KOG2442">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KNANQTR"/>
    <dbReference type="OrthoDB" id="29661at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030660">
        <property type="term" value="C:Golgi-associated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF103">
        <property type="entry name" value="INTRAMEMBRANE PROTEASE (IMPAS) FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912061" evidence="10">
        <location>
            <begin position="25"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="11">
        <location>
            <begin position="76"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="521" mass="55480" checksum="0C10E3A2AD5E066E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQB0</accession>
    <name>C1MQB0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57222</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057725.1">
        <property type="nucleotide sequence ID" value="XM_003057679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQB0"/>
    <dbReference type="STRING" id="564608.C1MQB0"/>
    <dbReference type="GeneID" id="9683535"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57222"/>
    <dbReference type="eggNOG" id="KOG1587">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2162425at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042505">
        <property type="entry name" value="DYNC2I1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16022:SF0">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16022">
        <property type="entry name" value="WD REPEAT DOMAIN 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="776" mass="82766" checksum="56F3379D78E524FE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQD2</accession>
    <name>C1MQD2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_67334</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058108.1">
        <property type="nucleotide sequence ID" value="XM_003058062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQD2"/>
    <dbReference type="GeneID" id="9683174"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67334"/>
    <dbReference type="OMA" id="MFASEMR"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045881">
        <property type="entry name" value="MNM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34682">
        <property type="entry name" value="AT HOOK MOTIF-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34682:SF1">
        <property type="entry name" value="PROTEIN METABOLIC NETWORK MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="2">
        <location>
            <begin position="77"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="311" mass="31946" checksum="98AEF9B11BD449B5" modified="2009-05-26" version="1">MNPAPAPARDGSGDPSLARGLNPGGRAESLADLAEPRPRRELALSPALLAYDAFADELRVALRNGTGERASDEAGMGIEKIIGARWRRMSASEREAHVEKAREARRKMLSRADADGGGGGGETAGKKAKKKQKRAAEAEADVAPDALALAPAKKKRGRGRPTKTAAAPAAAAAQLCVADAPPAGAPRPVTIAAPGALAAHPESSKQRERTRAKIVPNLTRVMTPTGPGETTPPGAENFVGRAVEGMVDGTFDAGFLLTARVDGALMRGIVWKEETTAVGKRGGKRRKARGAARRENAAAEGAAAGGDGDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQN1</accession>
    <name>C1MQN1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Post-GPI attachment to proteins factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PER1</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_57351</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the lipid remodeling steps of GPI-anchor maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PGAP3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058154.1">
        <property type="nucleotide sequence ID" value="XM_003058108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQN1"/>
    <dbReference type="STRING" id="564608.C1MQN1"/>
    <dbReference type="GeneID" id="9683227"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57351"/>
    <dbReference type="eggNOG" id="KOG2970">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WNIWDIE"/>
    <dbReference type="OrthoDB" id="419770at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007217">
        <property type="entry name" value="Per1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148">
        <property type="entry name" value="PER1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148:SF0">
        <property type="entry name" value="POST-GPI ATTACHMENT TO PROTEINS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04080">
        <property type="entry name" value="Per1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="2 7" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016483269" description="Post-GPI attachment to proteins factor 3" evidence="7">
        <location>
            <begin position="25"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="382" mass="42554" checksum="D37606F5061D596E" modified="2009-05-26" version="1">MVRRVVSLLSLLLLFLPTLAVATAEPPPPPPPPPKKPQNYAWVMDVCVRHDCFKTGCASLRDSNTGNVTTTAGACVSSCADGGTSLNGTSPREFDAALRVLRWDCASDCKYRCMTAVERARRREGLEPKKYYGKWPFARVLGTQEIVSAVASVANGGAHAWRLPTLTRAAKRRMRFAALWLGFTLVNINAWIWSVLFHCRELPFTHYMDYLGVNIVFFYALYAAFVRAFEPSARRAAALAVAFVAAAVAHVRHVNPPRQRYRYEYNMRAMFALIGAFWVVMLWWAFRGFRFRSRGGGGGGGGGGGGRGRGRHPGRRWLLAFGATFHVAALGEVFDYPPAYHLVDSHAVWHCVTPGCIWFWYLFVKEDLKVAQTATAKAKKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR01</accession>
    <name>C1MR01_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57475</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058220.1">
        <property type="nucleotide sequence ID" value="XM_003058174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR01"/>
    <dbReference type="GeneID" id="9683281"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57475"/>
    <dbReference type="OMA" id="FAWYRET"/>
    <dbReference type="OrthoDB" id="10506699at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="112" mass="12401" checksum="7076C483C717AD1D" modified="2009-05-26" version="1">MSGDGTSSSSLRAADAYKYNQRKMITPTYPEEGDYISVQGEELIFGAIFACVAWWMFKQLRSMLRAHRNVKRMAGVDDGGPVGVMIMSDDDDDGTDASEDGMDPGRPLKKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRN8</accession>
    <name>C1MRN8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoglycerate mutase (2,3-diphosphoglycerate-independent)</fullName>
            <ecNumber evidence="5">5.4.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_26927</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="5"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058907.1">
        <property type="nucleotide sequence ID" value="XM_003058861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRN8"/>
    <dbReference type="STRING" id="564608.C1MRN8"/>
    <dbReference type="GeneID" id="9684346"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26927"/>
    <dbReference type="eggNOG" id="KOG4513">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NCIHNAP"/>
    <dbReference type="OrthoDB" id="952271at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004619">
        <property type="term" value="F:phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010037">
        <property type="term" value="P:response to carbon dioxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16010">
        <property type="entry name" value="iPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1450.10:FF:000002">
        <property type="entry name" value="2,3-bisphosphoglycerate-independent phosphoglycerate mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="entry name" value="BPG-independent phosphoglycerate mutase, domain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011258">
        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637:SF0">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001492">
        <property type="entry name" value="IPGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 12" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="13">
        <location>
            <begin position="13"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="BPG-independent PGAM N-terminal" evidence="14">
        <location>
            <begin position="97"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="10">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="164"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="277"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH57362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="548" mass="59188" checksum="9C56C93C70A13089" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRW2</accession>
    <name>C1MRW2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_6143</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058942.1">
        <property type="nucleotide sequence ID" value="XM_003058896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRW2"/>
    <dbReference type="STRING" id="564608.C1MRW2"/>
    <dbReference type="GeneID" id="9684381"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6143"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CPEHQQM"/>
    <dbReference type="OrthoDB" id="534417at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="244" mass="26373" checksum="48C055F42C2CD184" modified="2009-05-26" version="1" fragment="single">LGSGGYGAVYRGSFEGGKIAVKAMFETGMNNMMSAAAARMMRKEALILCSLNHPNIIRVFGTVPEKGWLVMELCEGGSLDELLRDHDVALDSREKARLAKETATGVAYLHMKDVSIVHGDMKAANVLLTKRRVVKLCDFGMAEAKNRSKTMTSAGAGRVALTVAWSAPELFKGKQKTFASDVYALGMTLWQIFERQEPFSAMPEAAIVNQCLSGVRPDISAATPATAKKLIAMSWAGNPSSRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS94</accession>
    <name>C1MS94_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58398</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RUS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058643.1">
        <property type="nucleotide sequence ID" value="XM_003058597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS94"/>
    <dbReference type="STRING" id="564608.C1MS94"/>
    <dbReference type="GeneID" id="9684082"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58398"/>
    <dbReference type="eggNOG" id="KOG4249">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EGDRSMI"/>
    <dbReference type="OrthoDB" id="364779at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006968">
        <property type="entry name" value="RUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054549">
        <property type="entry name" value="UVB_sens_RUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770:SF29">
        <property type="entry name" value="PROTEIN ROOT UVB SENSITIVE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770">
        <property type="entry name" value="RUS1 FAMILY PROTEIN C16ORF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04884">
        <property type="entry name" value="UVB_sens_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein root UVB sensitive/RUS" evidence="3">
        <location>
            <begin position="161"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="679" mass="73537" checksum="474EF84C3347EB69" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSH1</accession>
    <name>C1MSH1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_40019</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059052.1">
        <property type="nucleotide sequence ID" value="XM_003059006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSH1"/>
    <dbReference type="STRING" id="564608.C1MSH1"/>
    <dbReference type="GeneID" id="9684118"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40019"/>
    <dbReference type="eggNOG" id="KOG0147">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WERRHSS"/>
    <dbReference type="OrthoDB" id="8123449at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12285">
        <property type="entry name" value="RRM3_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029123">
        <property type="entry name" value="RBM39_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006509">
        <property type="entry name" value="RBM39_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01622">
        <property type="entry name" value="SF-CC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48036">
        <property type="entry name" value="SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15519">
        <property type="entry name" value="RBM39linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="141"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="256"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="423"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="515" mass="57375" checksum="7EA8F227D6616C37" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSU0</accession>
    <name>C1MSU0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57821</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058737.1">
        <property type="nucleotide sequence ID" value="XM_003058691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSU0"/>
    <dbReference type="GeneID" id="9683800"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57821"/>
    <dbReference type="OrthoDB" id="498317at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1125" mass="126036" checksum="A9260C088E3C2583" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSU1</accession>
    <name>C1MSU1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_33371</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Magnesium transporter that may mediate the influx of magnesium.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058738.1">
        <property type="nucleotide sequence ID" value="XM_003058692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSU1"/>
    <dbReference type="GeneID" id="9684177"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33371"/>
    <dbReference type="eggNOG" id="KOG2662">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WIFRSIM"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF0">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="471" mass="51088" checksum="E02329C6A5993495" modified="2009-05-26" version="1">MIDAAVQSQSGGPLTGEGGAALPERKTRTGVKRAYMRRGAKKVWAAMNGGGSDVAESYGDVVPYDGGDGGSPIPAYGTAPVADAGVLQGRVIESVNGPVGGGIGEGAGVATKGLNGGAFQDDDANGGNGEKKKRKHKYHIAVNPPKQHGVMRINGPTASFKPSEYFRQSLSRRALLRDAELTPRDLRRIDPYLLQTNNTPALLVSDQTIIVNLGVRVIVRPDHALLFEPDTATAQRFLESLKTRGETKDTPGGVGGAPIPFELEVVEAALQETTSQLYAKLEFCEARCRHVSESLRTSINPVVLEELRLTKQSLVELDSRAGAIRQVLLDTLDDDDDITDFTISSTAELMTEEKEDEEEEVENLIEYYLQQTETVHSAAEQLLENTRDLEESISVSLSSRRYEVSKLELTLSIATFAAACGALITGVFGMNLRSCLEMSITAFYLTCFLIVSGMGWIFRSIMKFAQRQKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT36</accession>
    <name>C1MT36_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase</fullName>
            <ecNumber evidence="2">3.5.1.28</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_39706</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.</text>
            <dbReference type="EC" id="3.5.1.28"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.5.1.28" evidence="2"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058424.1">
        <property type="nucleotide sequence ID" value="XM_003058378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT36"/>
    <dbReference type="GeneID" id="9684231"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39706"/>
    <dbReference type="eggNOG" id="ENOG502SX14">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2303510at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="entry name" value="Peptidoglycan recognition protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051206">
        <property type="entry name" value="NAMLAA_amidase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30417">
        <property type="entry name" value="N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30417:SF1">
        <property type="entry name" value="N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="N-acetylmuramoyl-L-alanine amidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="5">
        <location>
            <begin position="63"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="267" mass="28746" checksum="E696664AC6A1A7BD" modified="2009-05-26" version="1">MSAYATSPPLGPTAPGHAPEVAAAMRPTDVAPAPRHGVRRRVHALSDDLGAIVGEDVSDATMTTEEEIRDAIDKVVIHYDACGSSAKCFDVLHNQRGLSCHFLIDVDGTIYQTLDARERAWHATTANDSSVGVELAHRGAVEMPKASAEDGTSTDATNSEHPHRVVGFVHGRELSQAPFADAQYASLAALVAGVMRACPRVRCEYPRGTDGEAATTKLEDDALRAFRGVLGHFHVQTNKIDPGPAFDWEGVAARVRKMREEEGEDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT56</accession>
    <name>C1MT56_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_6795</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058804.1">
        <property type="nucleotide sequence ID" value="XM_003058758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT56"/>
    <dbReference type="STRING" id="564608.C1MT56"/>
    <dbReference type="GeneID" id="9683870"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6795"/>
    <dbReference type="eggNOG" id="ENOG502R5TM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MPVEIDF"/>
    <dbReference type="OrthoDB" id="288942at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043039">
        <property type="term" value="P:tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000008">
        <property type="entry name" value="Similar to alanyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051335">
        <property type="entry name" value="Alanyl-tRNA_Editing_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462">
        <property type="entry name" value="ALANYL-TRNA EDITING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462:SF2">
        <property type="entry name" value="THREONYL AND ALANYL TRNA SYNTHETASE SECOND ADDITIONAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Threonyl/alanyl tRNA synthetase SAD" evidence="3">
        <location>
            <begin position="190"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="236" mass="24391" checksum="EED5F5A91C225C90" modified="2009-05-26" version="1" fragment="single">GDCALVLDRTIAYPAGGGQPSDTGRVVLGDGRATFAVRAVEISKEGVVRHLGRVEGADDDELSASEASVASVFEPGADVVVHVDVDRRVLHARVHSAGHLLDVAMSEIGLGPESGLVPAKGQHHVDGAYVEYSGKIDGLDKEKLARDLAAKMTELVERGGATSAETMPYDDAAAACGGSLPAYVAKDSTPRVVRVPAAAAGCPCGGTHVKDVREIGDVEIVGVRVKKGTTRVSYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT72</accession>
    <name>C1MT72_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_57960</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058815.1">
        <property type="nucleotide sequence ID" value="XM_003058769.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MT72"/>
    <dbReference type="GeneID" id="9684254"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57960"/>
    <dbReference type="eggNOG" id="KOG2042">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2242">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4692">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HCELDAK"/>
    <dbReference type="OrthoDB" id="566440at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000055">
        <property type="entry name" value="Ubiquitin conjugation factor e4 a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045129">
        <property type="entry name" value="RNF123/RKP/RSPRY1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057987">
        <property type="entry name" value="TPR_RNF123/RKP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13363:SF5">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13363">
        <property type="entry name" value="RING FINGER AND SRY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25576">
        <property type="entry name" value="TPR_RNF123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="14">
        <location>
            <begin position="138"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="15">
        <location>
            <begin position="1544"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="111"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="643"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1065"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1611"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="927"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="643"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="655"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1085"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1611"/>
            <end position="1623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1624"/>
            <end position="1634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH57270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1634" mass="174921" checksum="93E136E05F48A040" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT93</accession>
    <name>C1MT93_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_47280</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058449.1">
        <property type="nucleotide sequence ID" value="XM_003058403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT93"/>
    <dbReference type="GeneID" id="9683887"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47280"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="451" mass="53591" checksum="08580D0883839932" modified="2009-05-26" version="1" fragment="single">VLDREDPHARLPRARVLPLLRLAVRVARRVNKPGQVTLETRVDDLPLLARLLVDDLAGVLHDEPSFRDVLRGEQPPPAVLREHDLVLRYGQQVERAVAARGPARAHARVARRVARPVETLLATSEPRDRRRGGLGFRRGVRGRGRGRRASRGVATFRLRGGFLRGGFLLRSLLRALGVALDRHRDLRRRRCDAHARLGFFFWDQTRRRLADPLAPAEHLERRRLPERSDLERELELVHAEGALNRGGEVVARRIGRQRRQLRILHLRHGVQRSLLRRLRLRFRDRPQFLLRRRLLFLRRRRRLLYLRRRRRLLFLFLRRRRLLRRRSRSLLRRFRRFRRRRRRRRRRRRDVIVPPHRPRGGVLDERARRLDRGHDPLPLRHRPVPVLPPQRPALDDDRVRFLPRVDPLVLRRAKKLIRARRIARGLLASGRDAVVVRGRDHLRGPPRVALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTA7</accession>
    <name>C1MTA7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57999</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058454.1">
        <property type="nucleotide sequence ID" value="XM_003058408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTA7"/>
    <dbReference type="GeneID" id="9684272"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57999"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="129" mass="14694" checksum="DC11EBA88D8EEEB1" modified="2009-05-26" version="1">MTQLREMREVERGDATVNVRRRRVVRRATTNVGEAGAAPAATPAEEEASGGRGRAGEPEPEQSSFEAEEDAWQRSREAEWAVRAQLRNLKDRETRRRRRVTPPQKGKFVEPFADMSPTAHDDEWNHSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTS4</accession>
    <name>C1MTS4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chloroplast envelope protein translocase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TOC64-1</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_45582</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059369.1">
        <property type="nucleotide sequence ID" value="XM_003059323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTS4"/>
    <dbReference type="STRING" id="564608.C1MTS4"/>
    <dbReference type="GeneID" id="9684809"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45582"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WGLRTTH"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006169">
        <property type="entry name" value="PRK08310.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="3" id="KW-0946">Virion</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="47"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="316"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="432" mass="43843" checksum="74C297786B09B450" modified="2009-05-26" version="1">MACVARASFAAFASSSSSSSIPKTGKGGSFVDHCHGVEIKGGGASATDEGAGGVLSGLTFAVKDNLDLAGHRTGCGNPDWLRTRGGTPAATHAPCVAAMLDAGATCVGKTQMDELAWSLQGENAHYGTPSNPADPSRVPGGSSSGSACAVAAAHVDVALGTDTAGSVRVPASYVGVYGFRPSHGRVPVDGCVALARSFDCVGWFARDAATLMACGAALLPPDRPSGTIHADGFKRLIVATDAFATCDAGTREALISAIERAAKAGGDLEPAWWDSFRTLQTREVWLEHGAWIEETDPSFGPGVAERFAAAEAGGGAATDAIAAANAARDAITRRLNAMLEGGGVIVLPSAPSPALKTGASAEATEAFRARQLRLTTAAGMAGLPQARRFGRRIVSIPAATADGAPVGLSFIAARGRDEELLALTVSLERALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTU2</accession>
    <name>C1MTU2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47451</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059380.1">
        <property type="nucleotide sequence ID" value="XM_003059334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTU2"/>
    <dbReference type="GeneID" id="9684536"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47451"/>
    <dbReference type="OrthoDB" id="2018506at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="235" mass="24015" checksum="C0D6DA00487C6F72" modified="2009-05-26" version="1">MNAGGSSSSSSSASGEEKEKKKEGGGFDAAKALENVFSAIRESANRAEVKWGIGEKLRNQTSGFRESVVNLDAKLGVSKFVKNAAPPLWEKVQAFRATPAGRVANFIFYAWLFFSGFFWTIVSLGIAGAFLANLLFPSFFQERARKAQAQMAERVRAAQAAQAGGMGGMGGMGGMEGMGGAPGGMGGMGGNPYGGAGGDPFAGRRGGPGAGGGGGGRKSYGSGDVFDVDADVKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU71</accession>
    <name>C1MU71_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58692</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059443.1">
        <property type="nucleotide sequence ID" value="XM_003059397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU71"/>
    <dbReference type="STRING" id="564608.C1MU71"/>
    <dbReference type="GeneID" id="9684587"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58692"/>
    <dbReference type="eggNOG" id="ENOG502QU44">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MTPVWLS"/>
    <dbReference type="OrthoDB" id="504976at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase" evidence="2">
        <location>
            <begin position="184"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="403" mass="44724" checksum="B3E11778EA1659C8" modified="2009-05-26" version="1">MARPASLTRWTTSSQPPTGCLSRRRHRADAARGRRASSSPVVATKRASLMKRSRGEKRADIARATADVDAAEDVDADADADAEELAGEIEIPAEAKHVTVVDDFLPADLASVLRGVYDARHDDPRRVHAHRFVWDYWHVPQQYTLLRTPAADYFEDDDQYARLEDALRSYARTELGCGGLTPVWLSCYVDGCRQELHADVPHGPWAFVLSLTRWDARLFTGGETLVLNPETLEYWRTFRSDDVVERASLTTTIEPLFNRLTVFDPRVPHGVPVVEGVRDPKLGRLVLHGWFNDPEPFFDGALSETDAEETLLDVLPPLYETLGTLPRARGVVAAKVFVKRDGGVERVQFTADSLVPSPEGVGGELSATDIRDAIMLEIAGTLMETTFPASDGETRITLPFVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUI8</accession>
    <name>C1MUI8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58822</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059206.1">
        <property type="nucleotide sequence ID" value="XM_003059160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUI8"/>
    <dbReference type="GeneID" id="9684941"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58822"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028119">
        <property type="entry name" value="Snapin/Pallidin/Snn1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14712">
        <property type="entry name" value="Snapin_Pallidin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="251" mass="26645" checksum="FB767AC3E7769730" modified="2009-05-26" version="1">MTSSVETLSQGARARVPRPSVTLARRRPPSPPSPSRPSRASLIHSLISRPLSRRLPVSPSRPGLQREIAPAVSDCDASARASARSQSSLTASIERLHRELEALLAAVPEPEARAHADAISGLKSRVATLRASALATRAKMVRIHAGAKAMRRVDLAAVLDDDHDGLPPREDLYVGERDDDDDDDDDDDAEASEASEASEESASASASERTTGTPRSTRGGGATETDASGDDWHDADDANVDDSFRTTPGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUU1</accession>
    <name>C1MUU1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3'(2'),5'-bisphosphate nucleotidase 1</fullName>
            <ecNumber evidence="3">3.1.3.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Bisphosphate 3'-nucleotidase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Inositol-polyphosphate 1-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_47565</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3"/>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059252.1">
        <property type="nucleotide sequence ID" value="XM_003059206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUU1"/>
    <dbReference type="STRING" id="564608.C1MUU1"/>
    <dbReference type="GeneID" id="9684998"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47565"/>
    <dbReference type="eggNOG" id="KOG3099">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LMSDACR"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000012">
        <property type="entry name" value="Blast:Putative inositol monophosphatase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050725">
        <property type="entry name" value="CysQ/Inositol_MonoPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028:SF5">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH56384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="859" mass="90743" checksum="18D9AE6A8341451F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV04</accession>
    <name>C1MV04_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_34023</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059281.1">
        <property type="nucleotide sequence ID" value="XM_003059235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV04"/>
    <dbReference type="GeneID" id="9685032"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34023"/>
    <dbReference type="eggNOG" id="KOG4497">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CWHLNGD"/>
    <dbReference type="OrthoDB" id="308690at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990811">
        <property type="term" value="C:MWP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052778">
        <property type="entry name" value="Centrosome-WD_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="WD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220">
        <property type="entry name" value="WD REPEAT PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN WRAP73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="517" mass="56374" checksum="65D32FB3E92F31CF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVX0</accession>
    <name>C1MVX0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59540</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059825.1">
        <property type="nucleotide sequence ID" value="XM_003059779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVX0"/>
    <dbReference type="STRING" id="564608.C1MVX0"/>
    <dbReference type="GeneID" id="9685264"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59540"/>
    <dbReference type="OrthoDB" id="496335at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="130"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="384" mass="41428" checksum="6E4CE6B83FC9101F" modified="2009-05-26" version="1">MAQITTRLVAVATTASSPSPPTRNLRAASPRSSSTTTKTTTSPREYCGLSSNPSRLRPLRRRRRVAATPFALFGVGAASKTAPPSSSEIVPGQGAGSPKWPEIYDAIASDALRVRTIEASDLRSFLASREGARATLVDVRQAIEHDEWRLAGSINVPYAIPDPFWPRRVVGYAISIKGGLKGAFYTLIPALDAFQLPSLTPFNSTPISSLRTERPKVRNPRFVEDVDDAVCGGDANRRGDKKACVVLIDTKGGDLTRGPIREGSGTLDASDASCLRAAYELRQAGYADVRHVRGGLPGAIEDGELRWESETWGDFLRWLDTWNPDQRRLLMYSRLLPDPTNLPGVVGQLAVFTTIGLAYYDVGGIGTWAAANVPAACSFLPVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVY5</accession>
    <name>C1MVY5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_27647</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4 9">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the histone H2A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059832.1">
        <property type="nucleotide sequence ID" value="XM_003059786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVY5"/>
    <dbReference type="STRING" id="564608.C1MVY5"/>
    <dbReference type="GeneID" id="9685558"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27647"/>
    <dbReference type="eggNOG" id="KOG1757">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SYSEPRA"/>
    <dbReference type="OrthoDB" id="507009at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000005">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 9" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="11">
        <location>
            <begin position="24"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="12">
        <location>
            <begin position="108"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH55784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="140" mass="14583" checksum="81C2CDEB52F48CA7" modified="2009-05-26" version="1">MSGKGAKGLSGKGLSGKGGKVSSKGDKKKPTSRSVKAGLQFPVGRIHRFLKNRAASGGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDTLIKATIAGGGVIPHIHKSLINKSSKKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW82</accession>
    <name>C1MW82_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_11694</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060171.1">
        <property type="nucleotide sequence ID" value="XM_003060125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW82"/>
    <dbReference type="STRING" id="564608.C1MW82"/>
    <dbReference type="GeneID" id="9685317"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11694"/>
    <dbReference type="eggNOG" id="KOG3043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DWPRAKD"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051049">
        <property type="entry name" value="Dienelactone_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46623:SF6">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46623">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="112" mass="11969" checksum="68B7928540CD301F" modified="2009-05-26" version="1" fragment="single">MESVSFGPADAPITGYVCGDANAPSVVVLQEWWGVTENIKLQAQHLSKRGGYRCLVPDLYRGKLGVNAHHLMTNLDWPRAKDEIAAAATWLKTTGSPKVGAIGFCMGGALTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWS1</accession>
    <name>C1MWS1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59231</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059973.1">
        <property type="nucleotide sequence ID" value="XM_003059927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWS1"/>
    <dbReference type="GeneID" id="9685122"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59231"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="151" mass="16710" checksum="165C9DCAE7FA879F" modified="2009-05-26" version="1">MTPERTLSATSKALRACASGVDRATPLASALARPAFRAASAWVAFWLAAFASLVRRVGGAATLDAAVAATRRATMLARAAAPAAPRRRRAKGKEEEDDEEEDDEDEDDEYRREMRSVLAERDDWILRLTSTIAALRRDLKRERARRNRAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWT4</accession>
    <name>C1MWT4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_47645</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059684.1">
        <property type="nucleotide sequence ID" value="XM_003059638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWT4"/>
    <dbReference type="STRING" id="564608.C1MWT4"/>
    <dbReference type="GeneID" id="9685111"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47645"/>
    <dbReference type="eggNOG" id="KOG2163">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ICARAWG"/>
    <dbReference type="OrthoDB" id="515817at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
        <property type="entry name" value="ZW10_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZW10 C-terminal helical" evidence="3">
        <location>
            <begin position="845"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="418"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="651"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="799"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="139"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="427"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="660"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="806"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="904" mass="93807" checksum="5E184105DAFE3A03" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX50</accession>
    <name>C1MX50_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60029</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060630.1">
        <property type="nucleotide sequence ID" value="XM_003060584.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MX50"/>
    <dbReference type="GeneID" id="9685774"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60029"/>
    <dbReference type="eggNOG" id="ENOG502QQWT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="REAREMC"/>
    <dbReference type="OrthoDB" id="10690048at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="536"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="599"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="778"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1431"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1796"/>
            <end position="1821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1972"/>
            <end position="1991"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="173"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="379"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="659"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="870"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1209"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1393"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1483"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1670"/>
            <end position="1728"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1860"/>
            <end position="1887"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1934"/>
            <end position="1961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="250"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="616"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="814"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1433"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1450"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1799"/>
            <end position="1811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1991" mass="206107" checksum="BBAEB7CF58DD895B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXJ6</accession>
    <name>C1MXJ6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">assimilatory sulfite reductase (ferredoxin)</fullName>
            <ecNumber evidence="7">1.8.7.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MICPUCDRAFT_34650</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">DNA-binding protein that binds to both double-stranded and single-stranded DNA without significant sequence specificity to reversibly repress the transcriptional activity of chloroplast nucleoids by promoting DNA compaction and possibly regulate DNA replication.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Essential protein with sulfite reductase activity required in assimilatory sulfate reduction pathway during both primary and secondary metabolism and thus involved in development and growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O = sulfite + 6 reduced [2Fe-2S]-[ferredoxin] + 7 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23132"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.8.7.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="15">Monomer. Interacts with ferredoxin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast stroma</location>
            <location evidence="5">Chloroplast nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.</text>
    </comment>
    <dbReference type="EC" id="1.8.7.1" evidence="7"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060704.1">
        <property type="nucleotide sequence ID" value="XM_003060658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXJ6"/>
    <dbReference type="STRING" id="564608.C1MXJ6"/>
    <dbReference type="GeneID" id="9685846"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34650"/>
    <dbReference type="eggNOG" id="KOG0560">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WQMMLRL"/>
    <dbReference type="OrthoDB" id="1688044at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042644">
        <property type="term" value="C:chloroplast nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009337">
        <property type="term" value="C:sulfite reductase complex (NADPH)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050311">
        <property type="term" value="F:sulfite reductase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016002">
        <property type="term" value="F:sulfite reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000008">
        <property type="entry name" value="Sulfite reductase [ferredoxin], chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000014">
        <property type="entry name" value="Sulfite reductase [ferredoxin], chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011787">
        <property type="entry name" value="SiR_ferredoxin-dep"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010029">
        <property type="entry name" value="PRK13504.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02042">
        <property type="entry name" value="sir"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493:SF47">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="Nitrite and sulphite reductase 4Fe-4S domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="Nitrite/Sulfite reductase N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0883">Thioether bond</keyword>
    <feature type="domain" description="Nitrite/Sulfite reductase ferredoxin-like" evidence="18">
        <location>
            <begin position="119"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Nitrite/sulphite reductase 4Fe-4S" evidence="17">
        <location>
            <begin position="221"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Nitrite/Sulfite reductase ferredoxin-like" evidence="18">
        <location>
            <begin position="411"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00046513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH55473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="698" mass="76167" checksum="1F814FE6EBFC4989" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXM2</accession>
    <name>C1MXM2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60212</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060421.1">
        <property type="nucleotide sequence ID" value="XM_003060375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXM2"/>
    <dbReference type="GeneID" id="9686154"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60212"/>
    <dbReference type="eggNOG" id="ENOG502QT29">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EYGRAVW"/>
    <dbReference type="OrthoDB" id="2101583at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34966:SF1">
        <property type="entry name" value="OS04G0508100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34966">
        <property type="entry name" value="OSJNBA0043L24.15 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="86" mass="9671" checksum="586A2B021F58E123" modified="2009-05-26" version="1">MSFFSRVFSYVFNELLVEGLANSKTFQRFAVRTDAALKEAKTSGKLKDLSEATSNPGEAAKRVSEYMRTLMEDGKEVIEEVAKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY14</accession>
    <name>C1MY14_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_69274</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060795.1">
        <property type="nucleotide sequence ID" value="XM_003060749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY14"/>
    <dbReference type="GeneID" id="9685923"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69274"/>
    <dbReference type="OMA" id="FQRTREC"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="412" mass="46389" checksum="8ECA47E4BFF556A2" modified="2009-05-26" version="1">MRRFYFLLARRVVVVSRLFQRTRECRFLISSSASAISERAVAHDVARARTRRGVRLRAVASRASARGASRARVVRAPQRASPRARGPPASSSARPRPSSSSPRGWMARRRVLRVLGRRRLDPPASSLGDVRRARDDPNGGVASDVDQSGRVPRARRLRRGVHRARIRTRRRVGEARSRRALVPLVLARTRVRRGLRRAARHGRRPGVVGSRDRVARDRGRLRRDRAPARPRARLAESRALRAVGALPAGADVASDSDRPGRRVAVVRRRARVAARAGAVRVADADVGVRVVRHEGRQAKRGADSRRRVALRRAGVPGGERDRVRRRRPRRARVLAARARDRVVPLARRSRVAVELEHARREFEGEEGDRRRRVPEMVFVAAVGGVDVSLRVGRRDVRAVRERRGLLRVVRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY66</accession>
    <name>C1MY66_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60418</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060516.1">
        <property type="nucleotide sequence ID" value="XM_003060470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY66"/>
    <dbReference type="GeneID" id="9685954"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60418"/>
    <dbReference type="OMA" id="QQMILIP"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="124" mass="13139" checksum="6A86F926BC429704" modified="2009-05-26" version="1">MPSPPPPPPPASAAFAPSSSSSYPELLPVGVPERGAPRASTVPPRNAKHDPAWAPRAANALADARGAAPEDVARTLAELRATQDAVAKSLLDTEDAVLWLQKLEWLELQARFPYTGPHTTAFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY94</accession>
    <name>C1MY94_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47804</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060244.1">
        <property type="nucleotide sequence ID" value="XM_003060198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY94"/>
    <dbReference type="GeneID" id="9685974"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47804"/>
    <dbReference type="eggNOG" id="ENOG502S4JV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RMGLRNM"/>
    <dbReference type="OrthoDB" id="533503at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025512">
        <property type="entry name" value="DUF4399"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14347">
        <property type="entry name" value="DUF4399"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4399" evidence="2">
        <location>
            <begin position="117"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="208" mass="21698" checksum="6E51DA7289C1AC45" modified="2009-05-26" version="1">MTSLAAFAPRTAALRVAASKPARGTRRAAARAPPPPRASSSSDDEKDSSSESSDSRSSIPWTDRVNSRRFVLGGAVSAAMTLVMTGAPSPAAAKDGKNGVYWISPKDGATVPSKFPVKMGVKGYELAPASEGLQEGTGHHHIVVDGGVVPKGDAIPFDATHVHFGKAQKEGELELSPGQHTLTLQFANAKHESFGKKFASTITVNVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYI6</accession>
    <name>C1MYI6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">beta-ketoacyl-[acyl-carrier-protein] synthase I</fullName>
            <ecNumber evidence="2">2.3.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_3199</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.41" evidence="2"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060572.1">
        <property type="nucleotide sequence ID" value="XM_003060526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYI6"/>
    <dbReference type="STRING" id="564608.C1MYI6"/>
    <dbReference type="GeneID" id="9685731"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3199"/>
    <dbReference type="eggNOG" id="KOG1394">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QIGHCLG"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF297">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="4">
        <location>
            <begin position="1"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="481" mass="49357" checksum="5E749F1ABEBDE29B" modified="2009-05-26" version="1" fragment="single">RRVVVTGVGLATPLGVGRDLVWDGLVAGRSGVRALRREDIAEGERGWAQMTVRVGARVPRGTRPGEFDEKRWCDGELKGVAGSGSDESTTIRPAVGGGPRIAPFTGLALAAAAEALADAGWDASRVTDEQRNRAGVAIGAGMGHVADLVNAGALLERGKLRRVSPFFVPRILVNMAAGHVSMAHGLRGPNHAAATACATGAHAIGDAFRAVQRGDADVMVAGGTESCVDPVSYVGFARARALADPAAMTPRASKTKKKDKDIYNGSGEDVTEGCTDDVDPSTACRPFDATRAGFVMGEGAGVLVLESLESARRRGAIPYAEIRGYGQASDAHHITQPPSDGAGASRAMRAALEDGGVRPEDVGYVNAHATGTVVGDAAESRALATVFQERYLRGELSVSSTKGATGHLLGAAGAVEAAFAVLALSTKTLPPTLHLETPCPNAAPAGADLVPLIARVKPGLRAAMTNSFGFGGTNASLVFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYX6</accession>
    <name>C1MYX6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Pyruvate kinase</fullName>
            <ecNumber evidence="5 15">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MICPUCDRAFT_48021</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 15"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061116.1">
        <property type="nucleotide sequence ID" value="XM_003061070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYX6"/>
    <dbReference type="STRING" id="564608.C1MYX6"/>
    <dbReference type="GeneID" id="9686299"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48021"/>
    <dbReference type="eggNOG" id="KOG2323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TIMADIC"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="17">
        <location>
            <begin position="70"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="18">
        <location>
            <begin position="430"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="10"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH54766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="574" mass="61999" checksum="FAF5407834368D60" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZD2</accession>
    <name>C1MZD2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_60689</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061193.1">
        <property type="nucleotide sequence ID" value="XM_003061147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZD2"/>
    <dbReference type="STRING" id="564608.C1MZD2"/>
    <dbReference type="GeneID" id="9686378"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60689"/>
    <dbReference type="eggNOG" id="ENOG502QW6Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YLRWWFL"/>
    <dbReference type="OrthoDB" id="2017000at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471:SF1">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="309"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="608" mass="68092" checksum="A5CE0DCC32553102" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZD7</accession>
    <name>C1MZD7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">SNF2 super family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_60694</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061197.1">
        <property type="nucleotide sequence ID" value="XM_003061151.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MZD7"/>
    <dbReference type="GeneID" id="9686636"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60694"/>
    <dbReference type="eggNOG" id="KOG0386">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6017at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000017">
        <property type="entry name" value="ATP-dependent helicase BRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014978">
        <property type="entry name" value="Gln-Leu-Gln_QLQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51666">
        <property type="entry name" value="QLQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="QLQ" evidence="9">
        <location>
            <begin position="27"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="556"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="880"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="115"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1030"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1298"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1388"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1030"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1298"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1333"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1399"/>
            <end position="1410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1429" mass="154699" checksum="179FC2C7687C76DD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZM8</accession>
    <name>C1MZM8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60787</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061248.1">
        <property type="nucleotide sequence ID" value="XM_003061202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZM8"/>
    <dbReference type="STRING" id="564608.C1MZM8"/>
    <dbReference type="GeneID" id="9686687"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60787"/>
    <dbReference type="eggNOG" id="ENOG502QTY9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021434">
        <property type="entry name" value="DUF3082"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35733">
        <property type="entry name" value="OS02G0307800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35733:SF1">
        <property type="entry name" value="OS02G0307800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11282">
        <property type="entry name" value="DUF3082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="332" mass="35202" checksum="BB61BE327F71EE09" modified="2009-05-26" version="1">MASPLARIAPRVAALGSAARRRDARERRGAVAGARARALPAAYWITRSPALRRRRATGGAVAHAGRDHVAAASATPPPSSVARRHRVDEEADALAAATDGDDDGAGAGVGGVMSMSILAAVAYNALTGLTAMAYEGYDGIGVPDDEATPLQNAFGFAFTIFCAWYFVRVVKKRGNRAKEFRVANALPVRVRAGRPSKEERERRDAEQLAKSKKLSAKDAFVGGVTGLAISFALYQFAVVIGESFEGRLMPESYQARQITITVRTIVNGLAYLATFVYAANGTGLVLLAARKALDSLTGADLIDAQAAEWAERVERGGGEGEGEREGKEEERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N006</accession>
    <name>C1N006_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60925</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061044.1">
        <property type="nucleotide sequence ID" value="XM_003060998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N006"/>
    <dbReference type="STRING" id="564608.C1N006"/>
    <dbReference type="GeneID" id="9686483"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60925"/>
    <dbReference type="eggNOG" id="ENOG502RSUR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WTNLHIL"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF45">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="64"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="301" mass="30684" checksum="6A7D832C8B8221B0" modified="2009-05-26" version="1">MTLSASASAAFRGGASSSKLNSRSKMTATMISSPRSRPSLTRRAVVSPRAAATPADKSNIVVIGGTGATGSECVVQALARGSKVTVLARTPSKLAQPPGTAGEANAGKPIADLNLTVIQGSVTNAADVAKCITKDTTGVIVSLGGKTKDVGPTMLTDGTRNVIEAMKQNDVKRVAVVTSIGAGDSADQAPFVFKILMSTVMRSIFTDKNNQEQLFLGPAGPGKDLEFCVVRPGGLGLGPPTGVVNVIEGEAGSIARADVADFCLGALFEEAFPYIGKAPCISSVGGTSWTKDRQGKGVMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0B3</accession>
    <name>C1N0B3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48196</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061604.1">
        <property type="nucleotide sequence ID" value="XM_003061558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0B3"/>
    <dbReference type="STRING" id="564608.C1N0B3"/>
    <dbReference type="GeneID" id="9686804"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48196"/>
    <dbReference type="eggNOG" id="ENOG502S909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NVKCENC"/>
    <dbReference type="OrthoDB" id="38589at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016730">
        <property type="term" value="F:oxidoreductase activity, acting on iron-sulfur proteins as donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009773">
        <property type="term" value="P:photosynthetic electron transport in photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039987">
        <property type="entry name" value="PGRL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31032">
        <property type="entry name" value="PGR5-LIKE PROTEIN 1B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31032:SF1">
        <property type="entry name" value="PGR5-LIKE PROTEIN 1B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="329" mass="35298" checksum="B344093398DAE6F6" modified="2009-05-26" version="1">MAAIINATRAYSTLAAPRASTAPAKRARACAARVAKKTRGSVATRSASQDEAAVSPNASVSLSCSIDDPSSCSLADLEMLYIDALWNFYNGGSFTLSDEQYDRLREELNWQGSGFPTLRRYEVQFVEASIAYARGEPVVTDEEYEDLKRKVKAEGKRDDVTALLLYTKGQELLDPAQFLRLKDEMAKLDVDVGLRGATCTMSKTSDKLTSDSSAVTKMYLAIGAVPTVLGLTPYVLGSIFGFDIPFTAGVGFGLTVGALLTASIVNYTGLQNAEIVKGECPCCENEIKQFFGGESPENSVDYKCGVCGTTSKLNRTTMKIDQAGGIKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0H6</accession>
    <name>C1N0H6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Imidazole glycerol phosphate synthase hisHF</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="12">Glutaminase</fullName>
                <ecNumber evidence="12">3.5.1.2</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">Cyclase</fullName>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_48216</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Plastid</location>
            <location evidence="12">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">In the C-terminal section; belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="12"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061391.1">
        <property type="nucleotide sequence ID" value="XM_003061345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0H6"/>
    <dbReference type="STRING" id="564608.C1N0H6"/>
    <dbReference type="MEROPS" id="C26.965"/>
    <dbReference type="GeneID" id="9687081"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48216"/>
    <dbReference type="eggNOG" id="KOG0623">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GNYGHFV"/>
    <dbReference type="OrthoDB" id="10254903at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000094">
        <property type="entry name" value="Imidazole glycerol phosphate synthase hisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050064">
        <property type="entry name" value="IGPS_HisA/HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014640">
        <property type="entry name" value="IGPS_HisHF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235:SF2">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF/H IGP SYNTHASE SUBUNIT HISF/H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036936">
        <property type="entry name" value="IGPS_HisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 12 14" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="15">
        <location>
            <begin position="43"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR036936-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH54021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="578" mass="61519" checksum="1E4A9063726A2D10" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0P5</accession>
    <name>C1N0P5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48237</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061424.1">
        <property type="nucleotide sequence ID" value="XM_003061378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0P5"/>
    <dbReference type="STRING" id="564608.C1N0P5"/>
    <dbReference type="GeneID" id="9686864"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48237"/>
    <dbReference type="OrthoDB" id="501991at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="397"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="424" mass="44398" checksum="329DD8E7FF906F28" modified="2009-05-26" version="1">MFASYGPSTLRRKAAEVAAALEGTRVELGEGGGAVEDASRRKRAKTAATRPATAAAAGRAAAAAADVASAPPEVLYVDGARGEKTPMLCVDGPAALRAASDDAMAAMDAAGAAGVVPVPVPVAVPVPPVPIVVVGGRRTRPVCAQALPWARGFIGCPGIACDASHDFTSLFDHDGARACGNRKSTPLEVDNPKDATHFRARSAECPWSRRRVQRTLERASDPVTLRALLDEFAPRAKAVKKKHVDGQCSSCYSAHMTLIRSMDARKKLATSRRGGGGRGNDGEGDARAASGVDVHTLVSAVFTAPFFVKGAAEFGSMLVDGAVTPKSIASNPLLLHLFHVDAVKNIFITAMCYFASKFNIAERRRVCQLMMAMMLMLLPIFKIAPATTSGPPIPPPAIAYIGVTSVCYALALAGKEKKTRAKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0X0</accession>
    <name>C1N0X0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_37566</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061709.1">
        <property type="nucleotide sequence ID" value="XM_003061663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0X0"/>
    <dbReference type="STRING" id="564608.C1N0X0"/>
    <dbReference type="GeneID" id="9686908"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37566"/>
    <dbReference type="eggNOG" id="KOG1708">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HWSEAQK"/>
    <dbReference type="OrthoDB" id="359154at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_uL24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_uL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057264">
        <property type="entry name" value="Ribosomal_uL24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL24 C-terminal" evidence="4">
        <location>
            <begin position="90"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="155" mass="17009" checksum="A50BD35E69866731" modified="2009-05-26" version="1">MAGLTLTGSFAGAKLRTPTAAPSRVSGGFQVVAKKKWEKQELNKNGNPVRVSMHVKTNDKVVVVSGADKGKVTEVVELFTKSGEILCKDVNVKTKHVKPKGEGETGQIIQREFPIHHSNVMHWSEAQKTRSRIGHKVENGKKVRFLKKTGEVLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N193</accession>
    <name>C1N193_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_41700</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061772.1">
        <property type="nucleotide sequence ID" value="XM_003061726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N193"/>
    <dbReference type="STRING" id="564608.C1N193"/>
    <dbReference type="GeneID" id="9686968"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41700"/>
    <dbReference type="eggNOG" id="ENOG502QQ5J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AHENEWN"/>
    <dbReference type="OrthoDB" id="2020333at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36348">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36348:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="294" mass="32351" checksum="15D1D79C40080BDA" modified="2009-05-26" version="1">MSAALCPTLAVLTTEHRAKPSARRPARASAVSRTFRRSRDAVISRAKDATDEALTEVANMDSLIDLMVAADEDALVKLVAENVLSFDQKMWIRIAARSDAADSQESKDKLMALAGRCMKLIETMVETTESTIQESSVALETIVATAADPETGEFDVPLKAESIARLRKAVDDAVVDERMLNTVYAWIRKSDEDKLDGMVHILQHLLQCYAARELDNGETPLDVVIGAAASEWPAKFEEIIEGGFGEEAFTRDLQKRMEGVVLNLPNGSYAQRVQAEYLKEVEDRGKELYSAKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1K1</accession>
    <name>C1N1K1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_51434</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061836.1">
        <property type="nucleotide sequence ID" value="XM_003061790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1K1"/>
    <dbReference type="STRING" id="564608.C1N1K1"/>
    <dbReference type="MEROPS" id="A01.096"/>
    <dbReference type="GeneID" id="9687012"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51434"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KGEYMIS"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000009">
        <property type="entry name" value="Aspartic proteinase A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.225.10">
        <property type="entry name" value="Saposin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007856">
        <property type="entry name" value="SapB_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008138">
        <property type="entry name" value="SapB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011001">
        <property type="entry name" value="Saposin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008139">
        <property type="entry name" value="SaposinB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05184">
        <property type="entry name" value="SapB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03489">
        <property type="entry name" value="SapB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47862">
        <property type="entry name" value="Saposin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50015">
        <property type="entry name" value="SAP_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 10" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912319" evidence="12">
        <location>
            <begin position="28"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="14">
        <location>
            <begin position="107"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="13">
        <location>
            <begin position="342"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="13">
        <location>
            <begin position="436"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="540"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="572"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="138"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH54466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="647" mass="69521" checksum="99BCE7FB692605F3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1Y6</accession>
    <name>C1N1Y6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SNF1-like</name>
        <name evidence="15" type="ORF">MICPUCDRAFT_35658</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062199.1">
        <property type="nucleotide sequence ID" value="XM_003062153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1Y6"/>
    <dbReference type="STRING" id="564608.C1N1Y6"/>
    <dbReference type="GeneID" id="9687436"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35658"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QSPTIMN"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12122">
        <property type="entry name" value="AMPKA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14079">
        <property type="entry name" value="STKc_AMPK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14335">
        <property type="entry name" value="UBA_SnRK1_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000544">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000236">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="29"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="13">
        <location>
            <begin position="302"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="KA1" evidence="14">
        <location>
            <begin position="479"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="450"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH53911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="528" mass="58484" checksum="892BBCD0F6BB6748" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1Z3</accession>
    <name>C1N1Z3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="17">SNF2 super family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_51787</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061998.1">
        <property type="nucleotide sequence ID" value="XM_003061952.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N1Z3"/>
    <dbReference type="GeneID" id="9687643"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51787"/>
    <dbReference type="eggNOG" id="KOG0385">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0825">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17919">
        <property type="entry name" value="DEXHc_Snf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15545">
        <property type="entry name" value="PHD_BAZ2A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15543">
        <property type="entry name" value="PHD_RSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF33">
        <property type="entry name" value="OS01G0881000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="14">
        <location>
            <begin position="22"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="14">
        <location>
            <begin position="292"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="13">
        <location>
            <begin position="471"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="668"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="1083"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="59"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="518"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="865"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1043"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1270"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1354"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1552"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="2327"/>
            <end position="2365"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="2056"/>
            <end position="2085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="865"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="886"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1043"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="1056"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1274"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1287"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1383"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1564"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1581"/>
            <end position="1591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="2335"/>
            <end position="2344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH53710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2365" mass="255956" checksum="91D83DFF8BF48324" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N240</accession>
    <name>C1N240_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51840</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062023.1">
        <property type="nucleotide sequence ID" value="XM_003061977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N240"/>
    <dbReference type="GeneID" id="9687463"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51840"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="330" mass="35440" checksum="3072084AB9D87F3E" modified="2009-05-26" version="1">MRAVAETRALADAIDSFSSGGLNDRAHTRAALARAIERTMHEMSPRSVAWTLKALRDVPSVAAALSERGWDAVAAGAATAAREARPRRPRAYDAPDGVSVTAYVDAASALAEAWTTHRGGVCGADDVDVGGYDRAREGSWRVVARGFKKIATSRYPRDWRDVHRAFCAIANCAPLRRAAEEEGEALYGALRARAATAMRRFDIHQTRETFHSVSRLPRAIRALRTRAGAGDAASPSALETLAEAIETKFSPYIYDASGLKEALVAILGWEPPAAKSDDDDDGEGERSRDDDDDDANDAAAADDDAWLDRVAASDVVKVLHTGPHTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N268</accession>
    <name>C1N268_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_35710</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PITHD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062238.1">
        <property type="nucleotide sequence ID" value="XM_003062192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N268"/>
    <dbReference type="GeneID" id="9687479"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35710"/>
    <dbReference type="eggNOG" id="KOG1730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RLVFKPW"/>
    <dbReference type="OrthoDB" id="2635at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045099">
        <property type="entry name" value="PITH1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175">
        <property type="entry name" value="AD039 HT014 THIOREDOXIN FAMILY TRP26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175:SF1">
        <property type="entry name" value="PITH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PITH" evidence="2">
        <location>
            <begin position="9"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="213" mass="23010" checksum="B54AFC14167B1C1B" modified="2009-05-26" version="1">METCSHDHDCGGSDCGGSSLHGYVNHPRITALNAEDDDAAQRVFRPWDDRLNRDVVPLRSDDDDPELIVHVPFVSDVKVRGIMVIGGLTTAGAAPSRLNVFVNKAPGDINCDNASRKTPTQSFDLAEDFDGVLEYQTDFTKFQACASLTLHFPRNFRGETGGGDGVTEIFFVGLRGEGTGNRRDMIVTAVYETKPMPGDHKTVAEDGAPALGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2U8</accession>
    <name>C1N2U8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_20949</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="6"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061940.1">
        <property type="nucleotide sequence ID" value="XM_003061894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2U8"/>
    <dbReference type="REBASE" id="43656">
        <property type="entry name" value="M.Mpu1545ORF20949P"/>
    </dbReference>
    <dbReference type="GeneID" id="9687380"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20949"/>
    <dbReference type="eggNOG" id="KOG0919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00315">
        <property type="entry name" value="Cyt_C5_DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050750">
        <property type="entry name" value="C5-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098:SF1">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="341" mass="37856" checksum="8AD8BB39E7A631A7" modified="2009-05-26" version="1" fragment="single">FTFSELFAGVGGFGIALRSLGGSVVFASEMCPHARRTYAANNVVEIGDAPPALIVGDITDVCEDIIPPHDILTGGFPCQSFSQRGERKGFEDARGQLFREIARVLGARKPTAFFLENVEGLVTLDDGAAFQIILKELEDVGYDVHSRVYDAKGWVPQSRKRVYLVGFRKDAALATPFRWPPRRDDCGGTVDDILEEEVEEESPDDGYDADVEDDDANVFTSCEVSEYQMDRASAYFKRVHHREPDHPGFLFAETGGVARTLCASYRKSSAYNAELVRADATSTRRARPRYYTPREAARVMGFPETFQPDPERAYHELGNAVVPPLVRTIAEAILRSMGESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2Z4</accession>
    <name>C1N2Z4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_51975</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062290.1">
        <property type="nucleotide sequence ID" value="XM_003062244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2Z4"/>
    <dbReference type="STRING" id="564608.C1N2Z4"/>
    <dbReference type="GeneID" id="9687730"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51975"/>
    <dbReference type="eggNOG" id="ENOG502SRQM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CATEPSH"/>
    <dbReference type="OrthoDB" id="5823761at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009664">
        <property type="term" value="P:plant-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002963">
        <property type="entry name" value="Expansin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007112">
        <property type="entry name" value="Expansin/allergen_DPBB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31867">
        <property type="entry name" value="EXPANSIN-A15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50842">
        <property type="entry name" value="EXPANSIN_EG45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910598" evidence="2">
        <location>
            <begin position="19"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Expansin-like EG45" evidence="3">
        <location>
            <begin position="121"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="573" mass="61305" checksum="2B6811CC35CFB95E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3G9</accession>
    <name>C1N3G9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Ile)-lysidine synthetase</fullName>
            <ecNumber evidence="1">6.3.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_52167</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(34) in tRNA(Ile2) + L-lysine + ATP = lysidine(34) in tRNA(Ile2) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="1"/>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062610.1">
        <property type="nucleotide sequence ID" value="XM_003062564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3G9"/>
    <dbReference type="STRING" id="564608.C1N3G9"/>
    <dbReference type="GeneID" id="9687815"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52167"/>
    <dbReference type="eggNOG" id="ENOG502QQNE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CFGHHRG"/>
    <dbReference type="OrthoDB" id="495179at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032267">
        <property type="term" value="F:tRNA(Ile)-lysidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.320">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033:SF3">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="8">
        <location>
            <begin position="280"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="223"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="758" mass="83214" checksum="77A93F73458DA40D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3Y1</accession>
    <name>C1N3Y1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_48608</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062693.1">
        <property type="nucleotide sequence ID" value="XM_003062647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3Y1"/>
    <dbReference type="STRING" id="564608.C1N3Y1"/>
    <dbReference type="GeneID" id="9687894"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48608"/>
    <dbReference type="OMA" id="TWTYERE"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="389"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="441"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="605" mass="66644" checksum="0281227D3BAEA19E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N408</accession>
    <name>C1N408_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42305</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062709.1">
        <property type="nucleotide sequence ID" value="XM_003062663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N408"/>
    <dbReference type="GeneID" id="9687905"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42305"/>
    <dbReference type="eggNOG" id="ENOG502RYUS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GIFPWGK"/>
    <dbReference type="OrthoDB" id="199134at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005224">
        <property type="entry name" value="SfsA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30545">
        <property type="entry name" value="SUGAR FERMENTATION STIMULATION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30545:SF3">
        <property type="entry name" value="SUGAR FERMENTATION STIMULATION PROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="421" mass="44090" checksum="71190D9A8D4FFFBD" modified="2009-05-26" version="1">MPSAKRRKTTTVAAAAIVAAPPTPPPPPSSEPLLDLGPLEEGVLLCRPSARNRSPYVGDVRITSGPRAGSVAVTHLPNLDSGGKCRPGVKLLCRRQPGVFADTVGQYGTPKCELICQLLRCEEAENAVADIALGIAGGGVWVSAHPKLNEKLVEALLSRGAFDDRLHAAVGRAPSSDSATCPSDKNDPDDDPCRSPVKTQVTMRREATTSVSGGYRPDFVVSHADGASTVLETKQVVDTDYDARTAAEAAEAQAGHPVFLGGGGGDEEGEYTRAGIFPWGKRNQKGPDGEPVVSARAIEHLRELSSIARGKGNNAFNSDGNVTHAAVILLAGRHDVGGIRANGAACESFARYASRASNDGVRILAHKIRWGDGDDVGKAFDAGPLPMMAPTTEGRVLVVEKPKAAKKPKKEKKATAAKQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4D5</accession>
    <name>C1N4D5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cryptochrome DASH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_22169</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May have a photoreceptor function.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
        <text evidence="7">Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="5 7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062980.1">
        <property type="nucleotide sequence ID" value="XM_003062934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4D5"/>
    <dbReference type="STRING" id="564608.C1N4D5"/>
    <dbReference type="GeneID" id="9688211"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22169"/>
    <dbReference type="eggNOG" id="KOG0133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KFWRCGP"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000719">
        <property type="term" value="P:photoreactive repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014133">
        <property type="entry name" value="Cry_DASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02765">
        <property type="entry name" value="crypto_DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF22">
        <property type="entry name" value="CRYPTOCHROME DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="9">
        <location>
            <begin position="10"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="507"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="512"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="541"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="277"/>
            <end position="281"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="421"/>
            <end position="423"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="561" mass="61014" checksum="847A25EC6A6140F5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N522</accession>
    <name>C1N522_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_52770</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062896.1">
        <property type="nucleotide sequence ID" value="XM_003062850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N522"/>
    <dbReference type="GeneID" id="9688336"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52770"/>
    <dbReference type="OrthoDB" id="496451at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="118" mass="13133" checksum="A4790C906F49A6F8" modified="2009-05-26" version="1">MGKHPSSSDPTGDAWDRAFEDKRVLVEWGREGDAFDVKTHVVTRTVGLNVVDTVKGTPVKGWDPVEERVRCRIFTHPEVALIGDVAGFDVVETFGDMKGEHGLEDEDAQNMVIVLKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6B5</accession>
    <name>C1N6B5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42816</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063504.1">
        <property type="nucleotide sequence ID" value="XM_003063458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6B5"/>
    <dbReference type="GeneID" id="9688943"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42816"/>
    <dbReference type="OMA" id="SHRIACT"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="605" mass="59969" checksum="1527A87F5C9072F5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6F3</accession>
    <name>C1N6F3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_63948</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063329.1">
        <property type="nucleotide sequence ID" value="XM_003063283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6F3"/>
    <dbReference type="GeneID" id="9688769"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63948"/>
    <dbReference type="OrthoDB" id="498566at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="218" mass="22454" checksum="CEA1ED4754265A87" modified="2009-05-26" version="1">MPAVRCGADATRPHFISLVDRAGMTPAMATRAASSRPASARPRGAARASRRRAAAVASSSSSRDDDDDDGDRARSAPGGRRPPPPSSSSRRRRRTVGETLRIASTAAPILLAIAPHAAHAAGWYDDVPSGGGGGGGFAVGGADRGGPGGAAMADPEDYPYGTKDLAVDLASPLVAYKAVSWALNQEVPAWLDAIILFFTLAAIYVCAFDVTALDDRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6M6</accession>
    <name>C1N6M6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_22978</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063759.1">
        <property type="nucleotide sequence ID" value="XM_003063713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6M6"/>
    <dbReference type="GeneID" id="9689020"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22978"/>
    <dbReference type="eggNOG" id="ENOG502QV38">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RGDAPHE"/>
    <dbReference type="OrthoDB" id="118154at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03572">
        <property type="entry name" value="ENTH_like_Tepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035802">
        <property type="entry name" value="ENTH/VHS_tepsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039273">
        <property type="entry name" value="TEPSIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514:SF0">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="165" mass="18055" checksum="E22DB97D5698456C" modified="2009-05-26" version="1">MDALRGAVASAVHRGSDAVDAFARHRKIDAVCVDDAKPAAVYLLEELATATRSWPTDALDDVAAHVGKRIDHSSPHVKLKALRCLKYVCQRGDARFRRAAAKHCAARVRACVAHRGPPDEHRGDAPHEAVRDQATEAIAAMFPKDEVRSIHWSPYDPVRVVDADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6P5</accession>
    <name>C1N6P5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_53385</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063769.1">
        <property type="nucleotide sequence ID" value="XM_003063723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6P5"/>
    <dbReference type="GeneID" id="9689029"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53385"/>
    <dbReference type="OrthoDB" id="46395at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007511">
        <property type="entry name" value="DUF501"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37163">
        <property type="entry name" value="CONSERVED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37163:SF1">
        <property type="entry name" value="DUF501 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04417">
        <property type="entry name" value="DUF501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="121" mass="13698" checksum="FA1C59A54D09B3B6" modified="2009-05-26" version="1">MERREREIAAGSLSRSDEEVVNKDPEYDAAAAREFARQHEAYGSHRWSLLSEEDKAFATERGFDVVIRDVGIGGLRYKNQVKCLHLHYAHWLVTRDNIVGGWVHDELMKRAAATRGTTTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N732</accession>
    <name>C1N732_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53536</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063831.1">
        <property type="nucleotide sequence ID" value="XM_003063785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N732"/>
    <dbReference type="GeneID" id="9689104"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53536"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="67" mass="7196" checksum="EAE7CDE90D5AA6D0" modified="2009-05-26" version="1">MATPSSSPNTRSSARRSSRKAETAAKAAAAKAHPFKAYKPKPLKDLRFMSAAARKRAVRAMGAYDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N745</accession>
    <name>C1N745_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_53551</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063669.1">
        <property type="nucleotide sequence ID" value="XM_003063623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N745"/>
    <dbReference type="GeneID" id="9689110"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53551"/>
    <dbReference type="eggNOG" id="KOG1386">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6372431at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017110">
        <property type="term" value="F:nucleoside diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009134">
        <property type="term" value="P:nucleoside diphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF3">
        <property type="entry name" value="APYRASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="350" mass="37028" checksum="655990E35C9B3DFA" modified="2009-05-26" version="1">MTHRVYTHSALGLGQESAMEAHEMAMRGAGGRRREGRTAVRSRGVFGFGVFGGGGAGDPCAPRGKKDGGDGNFTACREAARRLLGVHDACPHASCGVGRHPRPFQPTLRGRFIATENFHHTARFLGLPEKASVADVASAGEEICAADWDTLVRTRSSGKDGEDELRKYCFSAAFIAAALGDAVGLREETKIAFRRVLLALDFLSRRFSPPRVPRFQSPTALPFNPKSDAFELHPDVASYGTALSNAVGGVDVDWALGAAVSFAARSGGPWDERVMMDGNGGGASVLVFVTVAVAALVAAAVAAARRTRAGRLAELRMRRLFGWPSKGALTLDRRSGSFGSGKLDAIEKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Q4</accession>
    <name>C1N7Q4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_43153</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063948.1">
        <property type="nucleotide sequence ID" value="XM_003063902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Q4"/>
    <dbReference type="GeneID" id="9689575"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43153"/>
    <dbReference type="OrthoDB" id="198480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008884">
        <property type="entry name" value="TylF_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40036">
        <property type="entry name" value="MACROCIN O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40036:SF1">
        <property type="entry name" value="MACROCIN O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="295" mass="32931" checksum="18F5DCC8F6719818" modified="2009-05-26" version="1">MAATETPQTPTPSWIHPSAASFYASDALRKTAQRVKTRRGVLNVALDRAWRGRGRGRGRGHLLWLEFGVWKGDDIAHIASWLREKHRRSGGGGRRGDGDGDGDDDDGAPVVHGFDSFEGLPAEWRDRFPAGAFDLCGAPPTLDGANIELHKGWFEDTVRAFLDDDDARRRRRRRRRDEKIKWRREKSLRNGVHIANGVVWEAVSTRTANDDDDTTTAAAAAAFVHADADLHASTATFLTALCERGLVVPGTVIVFDEYVNYDGWERGEFLAWEECRERFGRVLSHTGSHTTALAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N809</accession>
    <name>C1N809_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53902</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064187.1">
        <property type="nucleotide sequence ID" value="XM_003064141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N809"/>
    <dbReference type="STRING" id="564608.C1N809"/>
    <dbReference type="GeneID" id="9689441"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53902"/>
    <dbReference type="OMA" id="HCQFEME"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="255"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="390" mass="42476" checksum="E09C21E556CA7B97" modified="2009-05-26" version="1">MATPPRVAAAPRARRAAIVPAPVRSRRHGIAHRGASRRVVRVDALPFGFGKKDPAEEVPEEEEEEEDAVVDGNPFASIGGRVLGAVADAEEKASAAGNPFASFMSRDEPSEPEEEEEEEEEEETEDKGPAFGNPFASFGSLGKSINLSQTIDLDYGDDEEEEEDEIEEEEAPAIGNPFAGIASGMLARSRAAVKRTSRSAPPEPEPEPEKKQMGNWERTLKEGIKDGDIPTWTLDPEPVRGASLRPLRLRTDDVVVVGRDRGPGIDYAAKVGCVSGVHCQFEMEGQRLYVTDLGSTNGTYVDGQELRKNNRFRVFNGQIVRLGAENMNGEPFVVFDAKLTGANEMDRNSEYGQVQALVEALGGPQVVVNFLFINVAFQLGFYAITLLQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8I5</accession>
    <name>C1N8I5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein light chain roadblock</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ODA-LC7</name>
        <name evidence="12" type="ORF">MICPUCDRAFT_23376</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
            <location evidence="1 10">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GAMAD family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064272.1">
        <property type="nucleotide sequence ID" value="XM_003064226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8I5"/>
    <dbReference type="STRING" id="564608.C1N8I5"/>
    <dbReference type="GeneID" id="9689532"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23376"/>
    <dbReference type="eggNOG" id="KOG4115">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NEIMCAP"/>
    <dbReference type="OrthoDB" id="9985637at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.30:FF:000009">
        <property type="entry name" value="Dynein light chain roadblock"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016561">
        <property type="entry name" value="DYNLRB1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009998">
        <property type="entry name" value="DLC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 10" id="KW-0243">Dynein</keyword>
    <keyword evidence="12" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="11">
        <location>
            <begin position="7"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH51894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="98" mass="10796" checksum="6DADA978D93371DF" modified="2009-05-26" version="1">MTAVNEVEEAVKRINSHKGVLGVLIINNEGIPIKTTLENAETVQHAALITHFARKARAVVTALDPTNELTFLRVRSKSHEIMIAPDKDYTLVVLQNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8V6</accession>
    <name>C1N8V6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_5692</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064339.1">
        <property type="nucleotide sequence ID" value="XM_003064293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8V6"/>
    <dbReference type="STRING" id="564608.C1N8V6"/>
    <dbReference type="GeneID" id="9689780"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5692"/>
    <dbReference type="eggNOG" id="ENOG502QVD0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DFGHTHI"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46504">
        <property type="entry name" value="TRNASE Z TRZ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46504:SF2">
        <property type="entry name" value="TRNASE Z TRZ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="294" mass="31643" checksum="244DCB331523B688" modified="2009-05-26" version="1" fragment="single">LAGFRVEGVSVGGQETCVILPQLKIAFDSGRCPQRAVYADTLCLSHTHMDHVGGAGFYIASRALVSLPPPSVLIPAEARSRAAAFDAFIRSLRELDASELPHHLVPISPGETHVVSKLHVVRPFQTIHPVASQGYVVYGTKEKLKAEHAGKTGAQIKALRDAGAKVTDTIEVPEVAFTGDTSAEWIRRATATATEGGEGEGDVDVVARDALRAKLLICECTFVDDAVSPEGARDFGHTHIDELAAAARDGKFQNEAVLLIHFSARYRGREIEDAIAEKFPEEFAKRVTPLLVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9S5</accession>
    <name>C1N9S5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Heat shock protein 70 with TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_54607</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH50999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064665.1">
        <property type="nucleotide sequence ID" value="XM_003064619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9S5"/>
    <dbReference type="STRING" id="564608.C1N9S5"/>
    <dbReference type="GeneID" id="9690106"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54607"/>
    <dbReference type="eggNOG" id="KOG0101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0548">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PCKKKSE"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24028">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000012">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000020">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0346">Stress response</keyword>
    <keyword evidence="6 8" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="682"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH50999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="712" mass="77319" checksum="7A8D169B7B4ADE21" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9W0</accession>
    <name>C1N9W0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_43637</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064800.1">
        <property type="nucleotide sequence ID" value="XM_003064754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9W0"/>
    <dbReference type="GeneID" id="9690127"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43637"/>
    <dbReference type="OMA" id="KITMGLL"/>
    <dbReference type="OrthoDB" id="514832at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037647">
        <property type="entry name" value="HIRIP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019098">
        <property type="entry name" value="Histone_chaperone_domain_CHZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410:SF2">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09649">
        <property type="entry name" value="CHZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01082">
        <property type="entry name" value="CHZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone chaperone" evidence="5">
        <location>
            <begin position="323"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="64"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="358"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="134"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="184"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="419"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="431"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="444"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="478"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="492"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="525"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="551" mass="60162" checksum="31F548DE25A6157A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA62</accession>
    <name>C1NA62_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-S-isoprenylcysteine alpha-carbonyl methylesterase</fullName>
            <ecNumber evidence="3">3.1.1.n2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_23717</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + H2O = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48520"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="3.1.1.n2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Isoprenylcysteine methylesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.n2" evidence="3"/>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064736.1">
        <property type="nucleotide sequence ID" value="XM_003064690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA62"/>
    <dbReference type="STRING" id="564608.C1NA62"/>
    <dbReference type="ESTHER" id="9chlo-c1na62">
        <property type="family name" value="BD-FAE"/>
    </dbReference>
    <dbReference type="GeneID" id="9690177"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23717"/>
    <dbReference type="eggNOG" id="KOG1516">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MMFKPLI"/>
    <dbReference type="OrthoDB" id="6495301at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="BD-FAE-like" evidence="6">
        <location>
            <begin position="86"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="393" mass="43212" checksum="8AAB59094FA9368E" modified="2009-05-26" version="1">MPSRRIRLPAFAKATLRFIVRNVIVPLWLTLRLIAYVRVGWLIKFCGLVAFAAVLSPAFFRIAWTYYTSRRVKRDILYGSSPRNRLDLYLPEGCHYDAPVIVFVTGGMWIIGYKAWGALLSLTLMKQGFIVASLDYRNFPQGTVGDMTQDVSNGIGWVAKRARSFGGDAKKIFVVGQSAGAHLASSAILRQAEYETSLGGSVIDYGTAVARWSPRDLAGFVGISGVYAPDDRALAEHFNRKGLHKEVFWSIMEAGYSGARAEEALPRASPCAMLRDIPGVASSLPAVLLCHGNADGSAPPSESARFAEALRAAGSQARSILHWFPYDRRYYDGKTHTDPFVTDPISGGHDVLLEDIVRWVRRKDPRGGEIALPAMPALLPSLLVDVARRVVPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA75</accession>
    <name>C1NA75_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54790</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064743.1">
        <property type="nucleotide sequence ID" value="XM_003064697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA75"/>
    <dbReference type="GeneID" id="9690184"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54790"/>
    <dbReference type="OrthoDB" id="205639at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="entry name" value="PGBD-like superfamily/PGBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="PGBD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidoglycan binding-like" evidence="2">
        <location>
            <begin position="2"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="156" mass="16722" checksum="FA9053848210423C" modified="2009-05-26" version="1">MYFGPSTQEALCYFQASVQLPETGFVDADTWRALIGEERFIWGPPPGAIGFDEEAAAAAAAARSGSESESESDPAPPPLTASAASAAAWSKTIVPMNDNVDTGEDDGPQWGDAERNEPNEDPTGRDDAERRVRESQARSISHWPPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA88</accession>
    <name>C1NA88_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_49335</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064751.1">
        <property type="nucleotide sequence ID" value="XM_003064705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA88"/>
    <dbReference type="STRING" id="564608.C1NA88"/>
    <dbReference type="GeneID" id="9690192"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49335"/>
    <dbReference type="eggNOG" id="KOG4155">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="497743at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051510">
        <property type="entry name" value="SKI8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090:SF1">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="60"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="102"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="189" mass="18991" checksum="3266EBA18818F12F" modified="2009-05-26" version="1">MPLPRATGGGDGGKGAAGGGSSRFAHSIAFSPDGRRVVCGAMDGTVAVFDVPSRKLLHTLEGHAMPVRGVCFSVDSKTAFTACDDGYVHAYDVETRSLTQSFPGHDAWALSVAASPCGRAVVSCGADGTVKLWDLTQGLGVGGKMAQSVSDVSDATWGACFKPGTGGGGGGRLAAVGDDASVCLYDFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAK8</accession>
    <name>C1NAK8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_66110</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064979.1">
        <property type="nucleotide sequence ID" value="XM_003064933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAK8"/>
    <dbReference type="GeneID" id="9690420"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66110"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH50959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="105" mass="11622" checksum="81EAB0A36A898029" modified="2009-05-26" version="1">MKSFESRLPRRKSPYTRAFIVLAIALIGFMALFGVESPKLAPSRPQPQSSATKRACVGLAESRLLSFTEATTGACRDSERQRACQDVLVDMRVQNSGFHVTITIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGQ3</accession>
    <name>C1MGQ3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prasinophyte-specific protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PSP3</name>
        <name evidence="2" type="ORF">MICPUCDRAFT_61112</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054817.1">
        <property type="nucleotide sequence ID" value="XM_003054771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGQ3"/>
    <dbReference type="GeneID" id="9680617"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61112"/>
    <dbReference type="eggNOG" id="ENOG502SUZT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="497455at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="268" mass="29328" checksum="00B42A275E78FBFE" modified="2009-05-26" version="1">MSFASFANSRVSSPPHAPMLAAAATRATRRSARATLRWIAHPTRSSPFAHGGSARSATTHAAAAPAPQGGAKDASSRQQPAGAPPPSTRAQQQAQDRARQAQWQRQQQQQQPQPRPSHQQQQQQPQRAPQQQRQGGGGGGAYGGAAQTPARNGGGYRGMLPEEIDALYHQMQHLGSQWADLHAEAELLEESKKCVLASITLHYMNDGDSKSQGEARAFAAPEYKEHINKMVEARRRANQAKVEFEGIKTHMNLTRTYEASRREEMKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGS5</accession>
    <name>C1MGS5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Pyruvate kinase</fullName>
            <ecNumber evidence="5 15">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MICPUCDRAFT_49922</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 15"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055372.1">
        <property type="nucleotide sequence ID" value="XM_003055326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGS5"/>
    <dbReference type="STRING" id="564608.C1MGS5"/>
    <dbReference type="GeneID" id="9680800"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49922"/>
    <dbReference type="eggNOG" id="KOG2323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DDCESRC"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="16">
        <location>
            <begin position="10"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="17">
        <location>
            <begin position="366"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH60624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="488" mass="52913" checksum="0145CB929FB44B4B" modified="2009-05-26" version="1">MYADALYKFKSKVICTLGPVSREVPVLEKMLRAGMKVARFNFSHGEHSYHQHTLDNLRIASANTGILCGVLLDTKGPEIRTGFLANGDAVHLTAGSEVTLTTDYEHKGDETCIAVSYKNLAKDVRPGSKILAADGSITFTVLQCDVTGGKVTARVENNAKLGERKNMNVVDLPTITEKDTNDLLEWGVKNKVDFIAASFVRKGSDLDHIREVLGPAAATISIISKVENQEGLDNFKDIVDKSDGVMVARGDLGMEIPMHQIFLAQKRMIKRCNEQGKPVVTATQMLESMTGAPRPTRAEATDVANAILDGTDCVMLSGETAAGGYPVEAVSVMAQICAESEAHIDSEAQFRRILDRQKVPMDSIKESLASTAVRCAHKVGARLIISLARTGKLAQYIAKYRSPVPILMLILDEEGVEAAESVARRSLVYRGIVPVVVKTADHPPGNYREQMLEALNHAKAMGLVKTGDQVVGLHALGKDSVMKVLEVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH68</accession>
    <name>C1MH68_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_50069</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054900.1">
        <property type="nucleotide sequence ID" value="XM_003054854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH68"/>
    <dbReference type="STRING" id="564608.C1MH68"/>
    <dbReference type="GeneID" id="9680639"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50069"/>
    <dbReference type="eggNOG" id="ENOG502SE9I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AHTKHRY"/>
    <dbReference type="OrthoDB" id="498650at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038899">
        <property type="entry name" value="METTL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23108:SF3">
        <property type="entry name" value="METHYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23108">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="294" mass="32123" checksum="F3ADC9718AFDEBD5" modified="2009-05-26" version="1">MADPPRWKRDDIELCDSFEYMETTTFATTGGQVWGAARRLLDYLERTRDATGLDRPGVNVLELGSGTGFLGMTIARNARRDVGVVALTEMEAGGALEWLKKCVAKNEGKGLWRDGAVTCAACDWNEYAREDEERRATGTDAAPGPSVIDSTPWDLMIGSDLVYDDAGTRALPKVMRALLVRAKRARARARDEVTASAADADADADAASRRLALEPAFIYCHTLWRYELRDVDFFAQLTACGLAFEEVAEPGAPPPPEPPEPFAELFPEQRAAVFRVTLAPPRDEDARVRGGVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHG0</accession>
    <name>C1MHG0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_50169</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054949.1">
        <property type="nucleotide sequence ID" value="XM_003054903.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MHG0"/>
    <dbReference type="GeneID" id="9680332"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50169"/>
    <dbReference type="eggNOG" id="KOG1866">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YDYEREC"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000022">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056850">
        <property type="entry name" value="ARM_UBP34_24_USP9X_Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF827">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25010">
        <property type="entry name" value="ARM_UBP24_USP9X-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="6">
        <location>
            <begin position="1743"/>
            <end position="2145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="190"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1614"/>
            <end position="1658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2231"/>
            <end position="2270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2391"/>
            <end position="2416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1622"/>
            <end position="1639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2789" mass="304128" checksum="3DED3FFEF55043E6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHM5</accession>
    <name>C1MHM5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">V-type proton ATPase subunit C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_12280</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the V-ATPase C subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055517.1">
        <property type="nucleotide sequence ID" value="XM_003055471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHM5"/>
    <dbReference type="STRING" id="564608.C1MHM5"/>
    <dbReference type="GeneID" id="9680828"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12280"/>
    <dbReference type="eggNOG" id="KOG2909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YICYSIN"/>
    <dbReference type="OrthoDB" id="6605928at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14785">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1460.10">
        <property type="entry name" value="subunit c (vma5p) of the yeast v-atpase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1180">
        <property type="entry name" value="Vacuolar atp synthase subunit c, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004907">
        <property type="entry name" value="ATPase_V1-cplx_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036132">
        <property type="entry name" value="Vac_ATP_synth_c_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03223">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118203">
        <property type="entry name" value="Vacuolar ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="365" mass="41919" checksum="DDB1371EC6B5ABF3" modified="2009-05-26" version="1">MFVLRTSVNERTSVNGNQNDKPDRLCARRSTQFNVPELRVGAFDDLIELGDTISEVVSPLLDAVARRIQKQFVELHSSDGMDEQELTVDGIPPDQFLTSFEWDGAKNPTHRPIKKIVQELRENVATIDEELKVKTSEYAAAKAQLSGISRKTGWSLATRDLGDIVQESDIIETDNLVTLFVAVPIFSKKDWLKSYETLAHFVVPRSSKLIKEDEEYALYTVTLFHRVVDAFKSAAHEKSFQVREFHYNAETIQSEASERNDRVREVEERSAALDSLCRACYRNVISDWIHVCAIRIFVESVLRYGLPPNFLACIIKPHKKSEIKLRWILQDWLGHGALLNWDIFPEDEKRNMERSYPYVSFALIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHT1</accession>
    <name>C1MHT1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FAP125</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_50310</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055008.1">
        <property type="nucleotide sequence ID" value="XM_003054962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHT1"/>
    <dbReference type="STRING" id="564608.C1MHT1"/>
    <dbReference type="GeneID" id="9681114"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50310"/>
    <dbReference type="eggNOG" id="KOG0239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF28">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="188"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="628"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="707"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="577"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="660"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="292"/>
            <end position="299"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="728" mass="77382" checksum="4E3A32BD8AC1EB62" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHX2</accession>
    <name>C1MHX2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50353</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055029.1">
        <property type="nucleotide sequence ID" value="XM_003054983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHX2"/>
    <dbReference type="GeneID" id="9681134"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50353"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="179" mass="19056" checksum="3665367C6660E4C7" modified="2009-05-26" version="1">MGAEEEAASAPASESGDRASADGDRPGTSTGEEVGTTDGEASARSPRGGMFRGLLEDSFPELYVPPREPTPVPGEGEDGEEGEPGDDGDAAPREEAEADAPAEDAEGEGEGEDAEPEPEPEPDEYQLRIAEIENQARPRADVDLASARARRRVVSSRPRKSQTIERSPARLPLDIHRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIJ3</accession>
    <name>C1MIJ3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-B22</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase B22 subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MICPUCDRAFT_12445</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Mammalian complex I is composed of 45 different subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I LYR family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055140.1">
        <property type="nucleotide sequence ID" value="XM_003055094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIJ3"/>
    <dbReference type="STRING" id="564608.C1MIJ3"/>
    <dbReference type="GeneID" id="9680862"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12445"/>
    <dbReference type="eggNOG" id="KOG3466">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KWERNAP"/>
    <dbReference type="OrthoDB" id="13598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20263">
        <property type="entry name" value="Complex1_LYR_NDUFB9_LYRM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045292">
        <property type="entry name" value="Complex1_LYR_NDUFB9_LYRM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033034">
        <property type="entry name" value="NDUFB9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12868:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12868">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="17">
        <location>
            <begin position="3"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="52"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH60392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="105" mass="11964" checksum="EB4DC1CD2EA1E606" modified="2009-05-26" version="1" fragment="single">RPLVRHSLKTCLSWAVMRDVFYPERDRIRAMFEKNKSLRDPGAIERAIEDGEKTLDGYAHPDPYTVPSSYGGSKYARNPPPPGIEILYDFGRERGTTPGPDGHYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIQ9</accession>
    <name>C1MIQ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar transport chaperone protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_50662</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055174.1">
        <property type="nucleotide sequence ID" value="XM_003055128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIQ9"/>
    <dbReference type="STRING" id="564608.C1MIQ9"/>
    <dbReference type="GeneID" id="9680210"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50662"/>
    <dbReference type="eggNOG" id="KOG1161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4580">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NVNAYMR"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07751">
        <property type="entry name" value="PolyPPase_VTC4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14447">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="760"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="804"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="847"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="619"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="724"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="154"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="629"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="645"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="724"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="874" mass="95318" checksum="42D17F340EAE5B51" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIY3</accession>
    <name>C1MIY3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50741</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055215.1">
        <property type="nucleotide sequence ID" value="XM_003055169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIY3"/>
    <dbReference type="GeneID" id="9680364"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50741"/>
    <dbReference type="OrthoDB" id="498970at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="686"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="742" mass="78407" checksum="7503C866DAA23EE5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ69</accession>
    <name>C1MJ69_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61836</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEBP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055781.1">
        <property type="nucleotide sequence ID" value="XM_003055735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ69"/>
    <dbReference type="GeneID" id="9681010"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61836"/>
    <dbReference type="eggNOG" id="ENOG502QU4S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MPSKWSM"/>
    <dbReference type="OrthoDB" id="6424451at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="entry name" value="Regulatory factor, effector binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="HEME-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220:SF58">
        <property type="entry name" value="SOUL HEME-BINDING FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="Probable bacterial effector-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH61033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="177" mass="18728" checksum="B9E839C62AAB1B85" modified="2009-05-26" version="1">MGSVLGKISEELPRHEVLAKTAAYEIRRYAPCVVAETTYVSRDGMFSGDQGGSFMKLAKYIGVMAKPQNAEAAPIAMTSPVLMERAPGGGGGSGGGGGSGDGDHGFKMCFFLPASRFRKAADAPTPTSPEVAIRDVPARVMATKTFSGNLCQAAGYNPPWTPWFLKTNEVMLEVQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJH1</accession>
    <name>C1MJH1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_65211</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056619.1">
        <property type="nucleotide sequence ID" value="XM_003056573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJH1"/>
    <dbReference type="GeneID" id="9681820"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65211"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="133" mass="14612" checksum="E5E495FE0D6F2CB8" modified="2009-05-26" version="1">MNTSTFRSERGNNARVWMKRSRKMRYVVFQGHSVSHSLYSLAHSCRARLYGPTPCRTSRNACVTAFSPFFAPGYTVLAHLRPVKLLKVVFPAPVLANSLPALGVMPGAAGVAVVRGTVVVSIVERPVRVRVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJQ3</accession>
    <name>C1MJQ3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_46482</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055859.1">
        <property type="nucleotide sequence ID" value="XM_003055813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJQ3"/>
    <dbReference type="STRING" id="564608.C1MJQ3"/>
    <dbReference type="GeneID" id="9681633"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46482"/>
    <dbReference type="eggNOG" id="KOG2273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="XMTKVKV"/>
    <dbReference type="OrthoDB" id="5227681at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07596">
        <property type="entry name" value="BAR_SNX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="97"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="451"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="415"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="535" mass="55284" checksum="9F5E537C09C72533" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJT5</accession>
    <name>C1MJT5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_38366</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055874.1">
        <property type="nucleotide sequence ID" value="XM_003055828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJT5"/>
    <dbReference type="GeneID" id="9681892"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38366"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="236" mass="24799" checksum="AEE281CEDCC28352" modified="2009-05-26" version="1">MPAPTVAAAAALGVARAPTARDAAAARRRASATRPRRSRVVARRSQPRATTTTTTTTTPLRALPDDAADAAADALASKIDGMDADARASVVPILDDVLAAVASGDAFAYVPAATTTATTDDASASASATGVVKRVRAPGEVERFENAQRSSVFSQIGFERWGGGVGVAALQRTLGMYNNQIDADVLDEGAKLKLRISPAAPRFQRFQRFAINGFNVRSTVSTFDQRFQRSIASTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJU3</accession>
    <name>C1MJU3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55097</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055879.1">
        <property type="nucleotide sequence ID" value="XM_003055833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJU3"/>
    <dbReference type="STRING" id="564608.C1MJU3"/>
    <dbReference type="GeneID" id="9681436"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55097"/>
    <dbReference type="OMA" id="YASHEKF"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11717">
        <property type="entry name" value="THUMP_THUMPD1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2300.10">
        <property type="entry name" value="THUMP superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040183">
        <property type="entry name" value="THUMPD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452">
        <property type="entry name" value="THUMP DOMAIN CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452:SF10">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143437">
        <property type="entry name" value="THUMP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THUMP" evidence="2">
        <location>
            <begin position="156"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="291" mass="32007" checksum="4E17B30B4957B009" modified="2009-05-26" version="1">MRPDCSNFNLNRGIPEQLDASDTAPPPLPPWLRGFLVTARKREHAAVAGEEVASLCDDIFLREIDGVGGSREKTPPAGKRNARSTRVFAESLLIPGCPGSVFVAIKPDDADVDVVALAEKIIEDVDDDAARADVCWSRTAHAQRIIPVERIAPEYDLERLAREVIAKKFPARGRATDRGPPPTFKARSSTELVSYEEHSPAEHLHKMETEKMVADLVPDHYDVRLHDPDLTILVIVAGGSAMLAVTRGYDASQKFHKFHVRARDAARKSRHPKHPFAAVHAFAEKHGGFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK72</accession>
    <name>C1MK72_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U3 small nucleolar ribonucleoprotein component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MPP10</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_70680</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MPP10 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056332.1">
        <property type="nucleotide sequence ID" value="XM_003056286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK72"/>
    <dbReference type="STRING" id="564608.C1MK72"/>
    <dbReference type="GeneID" id="9681315"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70680"/>
    <dbReference type="eggNOG" id="KOG2600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="445326at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012173">
        <property type="entry name" value="Mpp10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04006">
        <property type="entry name" value="Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="628" mass="70887" checksum="FC43F53FBF20E246" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLJ0</accession>
    <name>C1MLJ0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Eukaryotic translation initiation factor 2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">EIF2A</name>
        <name evidence="10" type="ORF">MICPUCDRAFT_70190</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat EIF2A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056574.1">
        <property type="nucleotide sequence ID" value="XM_003056528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLJ0"/>
    <dbReference type="STRING" id="564608.C1MLJ0"/>
    <dbReference type="GeneID" id="9681594"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70190"/>
    <dbReference type="eggNOG" id="KOG2315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RCCAYSP"/>
    <dbReference type="OrthoDB" id="2194683at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011387">
        <property type="entry name" value="TIF2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Translation initiation factor beta propellor-like" evidence="9">
        <location>
            <begin position="222"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="425"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="516"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="532" mass="57528" checksum="1000D74A4EAA5E98" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLR3</accession>
    <name>C1MLR3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_14522</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056208.1">
        <property type="nucleotide sequence ID" value="XM_003056162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLR3"/>
    <dbReference type="STRING" id="564608.C1MLR3"/>
    <dbReference type="GeneID" id="9681612"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14522"/>
    <dbReference type="eggNOG" id="ENOG502QSIE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GTIKWAM"/>
    <dbReference type="OrthoDB" id="496065at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000014">
        <property type="entry name" value="Probable dual-specificity RNA methyltransferase RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="23S RRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544:SF5">
        <property type="entry name" value="RADICAL SAM CORE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01062">
        <property type="entry name" value="methyltransferase_(Class_A)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="106"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH59584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="358" mass="39030" checksum="9960BDC126178BEF" modified="2009-05-26" version="1">MAAKRFNLLGLTLSELKRFSADIGLPAYRGKQLRDHIYAGPPVRYIDDLVSLPKATRAALLAADVHIGRSSVHHVVVDSDGVVKLLLRLGDDKVIETVGIPSLERGKDRLTACVSSQVGCPMRCTFCATGKGGFTRNLAPHEIVDQVLSLEEHFGKRVTNVVFMGMGEPLLNTPNVLRAYTALNTEIGIGARHITISTVGVRGSLQMLAGARLQSTLAVSLHAPNQSLREVLIPSAKSYPLGELLNDCEQYFIATGRRVTFEYTLLAGINDSSEQAVELAELLHKKKLASHVNLIPYNPVHDAPDFARPDRATVFKFKNILEEMQVPASIRQSRGLEAAAACGQLRSSFQKISPEMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMM3</accession>
    <name>C1MMM3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_25887</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057430.1">
        <property type="nucleotide sequence ID" value="XM_003057384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMM3"/>
    <dbReference type="STRING" id="564608.C1MMM3"/>
    <dbReference type="GeneID" id="9682393"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25887"/>
    <dbReference type="eggNOG" id="ENOG502QTIS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FPHCNAV"/>
    <dbReference type="OrthoDB" id="497723at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052993">
        <property type="entry name" value="CFA-57"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32215">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32215:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="336"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="459"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="802"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="697"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="802"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="861" mass="96565" checksum="DE57FF39F046B24C" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMP1</accession>
    <name>C1MMP1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56603</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056963.1">
        <property type="nucleotide sequence ID" value="XM_003056917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMP1"/>
    <dbReference type="GeneID" id="9682402"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56603"/>
    <dbReference type="OrthoDB" id="10602296at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="139" mass="15502" checksum="B7D47942A026102F" modified="2009-05-26" version="1">MQSITSTTTLSARVQARLDPRASRVARVARRGRLPKTVPSRLRRRQIALVSSPRLRSQAPTRPKSARSTSVVPNATRDSKKAAAEEEESSFWKKVFLKDGQEEVSSADYQKFQKELNEKKAAAKARNADKGKFDGCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNB8</accession>
    <name>C1MNB8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">adenylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_56859</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the adenylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="2"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057552.1">
        <property type="nucleotide sequence ID" value="XM_003057506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNB8"/>
    <dbReference type="STRING" id="564608.C1MNB8"/>
    <dbReference type="GeneID" id="9682516"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56859"/>
    <dbReference type="eggNOG" id="KOG3079">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DAHEFHE"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="297"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="321"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="348" mass="38616" checksum="B2009A133A11DEE9" modified="2009-05-26" version="1">MDVDVDAFAAARTRAHLETYDASYETYNAIAARATAEASARALRYVPPKPPLARRVVFAMGGPGAGVATQCAKLAAERGEEYVHVRVGDVLRRAGEEGVERDTEVGALIRGMRVAKALVPTEIVLRFLREEMDALRASNKCVLIEGFPRTLEQAIAFEAKVRAVDFVLFFDGEPETMALRLLKPGRTITRASVERRYEHFVETYMPIVEHYKSEGMVHSIAADASVEEVNADALDAVALENMTRSELNQMRVTEAATRRLENDPAFAGEKTTMKPQCFFSHPFPAYLAAASAKNVRDATRKKDEYQVPAVKDLSKYPRSGSWKRWHANHPKNRTTRPSTNAGSVRSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNE8</accession>
    <name>C1MNE8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_25415</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057092.1">
        <property type="nucleotide sequence ID" value="XM_003057046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNE8"/>
    <dbReference type="STRING" id="564608.C1MNE8"/>
    <dbReference type="GeneID" id="9682084"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25415"/>
    <dbReference type="OMA" id="ECQNDSA"/>
    <dbReference type="OrthoDB" id="427960at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025836">
        <property type="entry name" value="Zn_knuckle_CX2CX4HX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46978">
        <property type="entry name" value="ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46978:SF1">
        <property type="entry name" value="ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14392">
        <property type="entry name" value="zf-CCHC_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="146" mass="15069" checksum="438AEBA00D51E174" modified="2009-05-26" version="1" fragment="single">MVCGKKGHRPMKCPERVSEATLKAGACVKCGELGHRLARCPSRIPDPDAPPEKCAQCGEEGHERVECPAFIASLFCFICGETGHKRVDCAKKIPDDDLKDGACFVCGEDGHAAHKCEKRHFAHGIGGGGGGGGGGGGGGRGRGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNN0</accession>
    <name>C1MNN0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gamma-tubulin complex component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_15650</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057137.1">
        <property type="nucleotide sequence ID" value="XM_003057091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNN0"/>
    <dbReference type="STRING" id="564608.C1MNN0"/>
    <dbReference type="GeneID" id="9682132"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15650"/>
    <dbReference type="eggNOG" id="KOG2001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QNMSGDP"/>
    <dbReference type="OrthoDB" id="496603at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="99"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="387"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="669" mass="73119" checksum="0C804110F03D4E3B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNX4</accession>
    <name>C1MNX4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_38619</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057187.1">
        <property type="nucleotide sequence ID" value="XM_003057141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNX4"/>
    <dbReference type="GeneID" id="9682170"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38619"/>
    <dbReference type="eggNOG" id="ENOG502QTEK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10594319at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046824">
        <property type="entry name" value="Mss51-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47570">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47570:SF1">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20179">
        <property type="entry name" value="MSS51_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial splicing suppressor 51-like C-terminal" evidence="2">
        <location>
            <begin position="165"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="753"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="454"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="772" mass="81473" checksum="7F32AEF4FA6C7328" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPJ9</accession>
    <name>C1MPJ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46927</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057591.1">
        <property type="nucleotide sequence ID" value="XM_003057545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPJ9"/>
    <dbReference type="GeneID" id="9683408"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46927"/>
    <dbReference type="eggNOG" id="ENOG502SDWV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="543641at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021373">
        <property type="entry name" value="DUF2993"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11209">
        <property type="entry name" value="LmeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="320" mass="33848" checksum="B473D08DF588959F" modified="2009-05-26" version="1">MPPSLASAPALAAATASSSSSFSASRASRSRTPASTSSPSILRHLASRRREDGEASSRRRRARGAPPTVPRALENPFAPPDLSGDLLARIAEFALSTNLRAFDDVTAVVDASVLGMLGGRVDGVIITGARWASRKNLTCATARFEVGAAAIDPIALVTERVVKLREPARGTAKLVFTTADFGNFLSHPLTVAAQRSHAWPSTRAPGGFELVGERVALEDGAVVFEGRAVEGGGGREGGGGYRIAMRPKRAGDGGVVVECRRVSAAQRELLRTALVRRPRGGRARRLTFRSIDGSRRSRGLVGVRAARVLYSSRDVIFILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPL8</accession>
    <name>C1MPL8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">adenylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_32766</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the adenylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="3"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057603.1">
        <property type="nucleotide sequence ID" value="XM_003057557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPL8"/>
    <dbReference type="STRING" id="564608.C1MPL8"/>
    <dbReference type="GeneID" id="9683415"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32766"/>
    <dbReference type="eggNOG" id="KOG3078">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YHEMLDG"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036193">
        <property type="entry name" value="ADK_active_lid_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57774">
        <property type="entry name" value="Microbial and mitochondrial ADK, insert 'zinc finger' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="265" mass="28420" checksum="1EEF5AA772C628E6" modified="2009-05-26" version="1">MASFTLTASSAIATPRARFAAGGDASRAELRARARAPARSSSPRDRASAVVALAAATKTPKRVVIAGAPASGKGTQCELIVEKFGLVHISAGDLLRAAVAEGTPAGLEAKAYMDRGDLVPDEVVVTMVKDALDCEEAEENGWLLDGYPRSASQADAIEKEGITPDVFLLLNVPDEMLIERVVGRRLDPETGAIYHVKFFPPPEDVVDRLTIRSDDTEEKAKNRLAVHHSNVEAVVGRYEGKIREIDGDRAKTEVFAEIASILDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPN3</accession>
    <name>C1MPN3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56970</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057611.1">
        <property type="nucleotide sequence ID" value="XM_003057565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPN3"/>
    <dbReference type="STRING" id="564608.C1MPN3"/>
    <dbReference type="GeneID" id="9683422"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56970"/>
    <dbReference type="eggNOG" id="KOG1546">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3223806at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="3">
        <location>
            <begin position="593"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="497"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="835"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="381"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="429"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="466"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="849"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="989" mass="105804" checksum="086D74FE12FF0EBF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPP5</accession>
    <name>C1MPP5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_70265</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057618.1">
        <property type="nucleotide sequence ID" value="XM_003057572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPP5"/>
    <dbReference type="GeneID" id="9683015"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70265"/>
    <dbReference type="eggNOG" id="ENOG502R33M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="514051at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47489">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASES (NAT) SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47489:SF2">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="96"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="204" mass="22396" checksum="CF8CE0876FE1FAA5" modified="2009-05-26" version="1">MAGFPLERRTLETYLRGAVPAFPYGTYLVGRLRAPRVGVGGGGEGENFIGDDDDGFDDGSPPGGPASSWSEEKSSAHGPIVCTVGVSFNAATRRRFTSLSPPTDQAYLSDLVVFESERGEGLGRAMLRAAETFARDMKSEHMYLHVATKKPGVVRLYRGAGYTIRGVDPGLFGWRGRLLMRKEMGAEDALVARREYKMVRREMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPW4</accession>
    <name>C1MPW4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_16164</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058020.1">
        <property type="nucleotide sequence ID" value="XM_003057974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPW4"/>
    <dbReference type="STRING" id="564608.C1MPW4"/>
    <dbReference type="GeneID" id="9683081"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16164"/>
    <dbReference type="eggNOG" id="KOG0110">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FNNTCIQ"/>
    <dbReference type="OrthoDB" id="439639at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12565">
        <property type="entry name" value="RRM1_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12317">
        <property type="entry name" value="RRM4_RBM19_RRM3_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12320">
        <property type="entry name" value="RRM6_RBM19_RRM5_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="36"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="378"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="704"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="812"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="660"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="889"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="291"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="669"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="889"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="921"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="930" mass="99277" checksum="DFAB3AE8F7487FF0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQG0</accession>
    <name>C1MQG0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">[RNA-polymerase]-subunit kinase</fullName>
            <ecNumber evidence="3">2.7.11.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">CDKD</name>
        <name evidence="18" type="ORF">MICPUCDRAFT_3997</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.23" evidence="3"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058121.1">
        <property type="nucleotide sequence ID" value="XM_003058075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQG0"/>
    <dbReference type="STRING" id="564608.C1MQG0"/>
    <dbReference type="GeneID" id="9683189"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3997"/>
    <dbReference type="eggNOG" id="KOG0659">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CLESEYF"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070985">
        <property type="term" value="C:transcription factor TFIIK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07841">
        <property type="entry name" value="STKc_CDK7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000554">
        <property type="entry name" value="CMGC/CDK/CDK7 protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000097">
        <property type="entry name" value="Putative cyclin-dependent kinase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037770">
        <property type="entry name" value="CDK7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF0">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="3"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="9"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR637770-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR637770-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH58072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="301" mass="33905" checksum="FD1C88CD5291BBC3" modified="2009-05-26" version="1" fragment="single">ERYIKGAVLGEGTFGVVTKAEDTLTRRHVAIKKIRLGKYKEGVNFTAIREIKLLMELRHPHVIELVDVFPHKRNLNLVFEMCESDLEAVVKDKFLPLGTPEVKSYVKMTLEAVAYCHASWVLHRDLKPNNLLIAPNGALKLADFGLARVFGSPNRRFTHQVFARWYRAPELLLGSKAYGPGVDMWAIGCVFAELMLRKPYFPGSSDIDQLGRIYAGLGTPTEENWPGHKNMPDYVEFSHGVAPPLRQLFTTAPPEALDLLQKLLAFDPNKRLSAADALKHAYFSSRPFATPFPDLPRPTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQM6</accession>
    <name>C1MQM6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_57346</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057786.1">
        <property type="nucleotide sequence ID" value="XM_003057740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQM6"/>
    <dbReference type="STRING" id="564608.C1MQM6"/>
    <dbReference type="GeneID" id="9683224"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57346"/>
    <dbReference type="eggNOG" id="KOG3310">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IGGHAMS"/>
    <dbReference type="OrthoDB" id="10258924at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000003">
        <property type="entry name" value="Riboflavin synthase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006767">
        <property type="entry name" value="PRK09289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009566">
        <property type="entry name" value="PRK13020.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098:SF0">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="47"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="4">
        <location>
            <begin position="47"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="4">
        <location>
            <begin position="144"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="144"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="249" mass="26601" checksum="02551495381DC41C" modified="2009-05-26" version="1">MSVGVAPARAASGFRRACRGAALEPRVVALRPLPARRRAGVVAPTALFTGLVQGTAEVISFDDVGDFARLKLKFPPKTLDGILIGASVACNGTCLTVVEVDGDVAGFDLIVETLRATNLGELKPGSSVNYERSARVGDEIGGHTVSGHVHAKATIVEQEDTENNRKVVFELDEKWSKYILPKGFVAVDGCSLTVGETSPGRFNVWLIPETIRQTVFAEKSVGSTVNIEIESQTQTIVDTIERVLAERGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQQ1</accession>
    <name>C1MQQ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57370</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058164.1">
        <property type="nucleotide sequence ID" value="XM_003058118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQQ1"/>
    <dbReference type="STRING" id="564608.C1MQQ1"/>
    <dbReference type="GeneID" id="9683237"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57370"/>
    <dbReference type="OMA" id="IKLWFHG"/>
    <dbReference type="OrthoDB" id="10671696at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="925"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="952" mass="100423" checksum="625B4D5C024E669A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR04</accession>
    <name>C1MR04_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MICPUCDRAFT_57478</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>2 ATP + H(+) = P(1),P(4)-bis(5'-adenosyl) tetraphosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34935"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:34936"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>tRNA(Gly) + glycine + ATP = glycyl-tRNA(Gly) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:16014"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Axon</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="5"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058222.1">
        <property type="nucleotide sequence ID" value="XM_003058176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR04"/>
    <dbReference type="STRING" id="564608.C1MR04"/>
    <dbReference type="GeneID" id="9683660"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57478"/>
    <dbReference type="eggNOG" id="KOG2298">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MEMQYFV"/>
    <dbReference type="OrthoDB" id="57698at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070150">
        <property type="term" value="P:mitochondrial glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00858">
        <property type="entry name" value="GlyRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01200">
        <property type="entry name" value="WHEPGMRS_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.230:FF:000001">
        <property type="entry name" value="Glycine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.200:FF:000001">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000004">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000158">
        <property type="entry name" value="Glycyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000010">
        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000738">
        <property type="entry name" value="WHEP-TRS_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00458">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00991">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51185">
        <property type="entry name" value="WHEP_TRS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WHEP-TRS" evidence="19">
        <location>
            <begin position="10"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="18">
        <location>
            <begin position="99"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEH58173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="683" mass="75662" checksum="43E2A23AF099B305" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRA8</accession>
    <name>C1MRA8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57588</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057899.1">
        <property type="nucleotide sequence ID" value="XM_003057853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRA8"/>
    <dbReference type="GeneID" id="9683709"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57588"/>
    <dbReference type="OMA" id="VMQNKEE"/>
    <dbReference type="OrthoDB" id="498777at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="179" mass="20953" checksum="C211C6AE4C20BA77" modified="2009-05-26" version="1">MAKRAGGVSLWRRVTNYVKHDLREIVWPRPMDDPPGTTSVFEGLTARDHARVWSNAWREYKRGWRWYFGEPESDREERIAREKAEGTHVEDEYEALDREEFEALKEEAGRMAAAGKAMGHDGWKHQLQMFYRTRGKVYTRSIAEFVKGYREGMAESTLRSRMAQQGEEEEPPPPPPPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRU4</accession>
    <name>C1MRU4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="3">1.3.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">MICPUCDRAFT_17474</name>
    </gene>
    <organism evidence="23">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="19">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="17">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="18">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Dus family. Dus3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="3"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058570.1">
        <property type="nucleotide sequence ID" value="XM_003058524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRU4"/>
    <dbReference type="STRING" id="564608.C1MRU4"/>
    <dbReference type="GeneID" id="9684373"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17474"/>
    <dbReference type="eggNOG" id="KOG2333">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CEMVFAR"/>
    <dbReference type="OrthoDB" id="259935at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000067">
        <property type="entry name" value="tRNA-dihydrouridine(47) synthase [NAD(P)(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="14" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="21">
        <location>
            <begin position="67"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00045934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EEH57025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="430" mass="47667" checksum="FDA67A22024DDD09" modified="2009-05-26" version="1">MGVKTTSRSNGKCSGFDEAGTKRRKGENGGITEGIDVAEVNAVEQNAFRRMNAREKQTVDFSDKLYLAPLTTVGNLPFRRVCKGLGADITCGEMAMCTNLLQGQPNEWALLRRHPSEDLFGVQICGGYSDSVARCSQLIDDVIVSQGGCDFVDINMGCPIDLVCNKGGGSMLLERHNRMEQIARSASSLLSCPLTLKTRTGYYDNKRVAHDIVPKLKDWGVAAVTLHGRSRQQRYSRLADWEYIKNTANVSSVPLIGNGDVFNFRDYEKNVEGTGVMTCMIARGALIKPWIFTEIKERRDWDISATERLDMLKRFAAYGLEHWGSDERGVENTRRFLLEWLSFLHRYIPVGLLEVVPTGIHQRPPSYVGRNELETLFASTQAEDWVKITTMLLGPPPAGFNFVPKHKSNAYGAGEKGAALADFDGLSAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS30</accession>
    <name>C1MS30_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_39924</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KRI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058975.1">
        <property type="nucleotide sequence ID" value="XM_003058929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS30"/>
    <dbReference type="STRING" id="564608.C1MS30"/>
    <dbReference type="GeneID" id="9684054"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39924"/>
    <dbReference type="eggNOG" id="KOG2409">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KIMATRH"/>
    <dbReference type="OrthoDB" id="10252032at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018034">
        <property type="entry name" value="Kri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024626">
        <property type="entry name" value="Kri1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490:SF5">
        <property type="entry name" value="PROTEIN KRI1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490">
        <property type="entry name" value="ZINC FINGER, ZZ TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05178">
        <property type="entry name" value="Kri1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12936">
        <property type="entry name" value="Kri1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kri1-like C-terminal" evidence="3">
        <location>
            <begin position="603"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="484"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="548"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="665"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="549"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="693"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="711"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="740"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="755"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="765"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="793"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="804" mass="87238" checksum="2EFA677BB70F8E09" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS59</accession>
    <name>C1MS59_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ph-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_47387</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058629.1">
        <property type="nucleotide sequence ID" value="XM_003058583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS59"/>
    <dbReference type="STRING" id="564608.C1MS59"/>
    <dbReference type="GeneID" id="9684068"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47387"/>
    <dbReference type="eggNOG" id="ENOG502QR9B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HECSREA"/>
    <dbReference type="OrthoDB" id="548564at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053277">
        <property type="entry name" value="Endomembrane_traffic_mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45005">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45005:SF2">
        <property type="entry name" value="PROTEIN HLB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="519" mass="55061" checksum="1B40456AB69F7A20" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS96</accession>
    <name>C1MS96_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_47403</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058644.1">
        <property type="nucleotide sequence ID" value="XM_003058598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS96"/>
    <dbReference type="STRING" id="564608.C1MS96"/>
    <dbReference type="GeneID" id="9684451"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47403"/>
    <dbReference type="eggNOG" id="ENOG502RZIT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KWEAVED"/>
    <dbReference type="OrthoDB" id="2014299at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009579">
        <property type="term" value="C:thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025564">
        <property type="entry name" value="CAAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033344">
        <property type="entry name" value="CURT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33222">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33222:SF4">
        <property type="entry name" value="PROTEIN CURVATURE THYLAKOID 1A, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14159">
        <property type="entry name" value="CAAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanobacterial aminoacyl-tRNA synthetase CAAD" evidence="3">
        <location>
            <begin position="64"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="150" mass="16191" checksum="D24C14D12F42480B" modified="2009-05-26" version="1">MAAIIAPSAVLAPRVVASKARAARTLKASSFKGAKVAPKTTFTRSKVSTMAVADSKINADEVLKTISDKWEDTENKSTVITYVAGAAAVVWLSGTVVGAINSIPILPKVMELVGLGYSSWFVYRYVLYKDSRKELLEQFDALKDKVSGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSI8</accession>
    <name>C1MSI8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_3588</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058329.1">
        <property type="nucleotide sequence ID" value="XM_003058283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSI8"/>
    <dbReference type="STRING" id="564608.C1MSI8"/>
    <dbReference type="GeneID" id="9684128"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3588"/>
    <dbReference type="eggNOG" id="ENOG502QS4Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DDAGEWA"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="9">
        <location>
            <begin position="6"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="313" mass="35662" checksum="E0D445DAC6DD61A7" modified="2009-05-26" version="1" fragment="single">TSATSSFVAREGGRFVLDGATFHVAGANCYYLAYSSGADAGSYEHDWVKEVLDEAQSLELNVLRVWSFQDEWWQRDRALQPAPGQYNERFLVALDGLIVESARRDIRLLLCLTNYWEDYGGAIAYVNWAHAAGERRADGHSLDRQEDFFTSQLCRAWFKRFATHVLSRVNTITGVAYRDDPAIFAWELINEPRVLGDASGDILQNWIDEMSAHAKSVDANHMLTVGIEGFWGKTSPHRVGENPIDGAERMGCDFVRNFLNPNLDFASVHVWPDLWLYCDDDCKFEFMKTWIAGHLEESRDTFDKPVLLEEFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSM7</accession>
    <name>C1MSM7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_57748</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058353.1">
        <property type="nucleotide sequence ID" value="XM_003058307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSM7"/>
    <dbReference type="GeneID" id="9683811"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57748"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF137">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="43"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="241"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="480"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="490"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="505" mass="54385" checksum="A872B267173069B2" modified="2009-05-26" version="1">MSGVVDAFAAWLTSHGASFDAVELRDATADDAARRSAANDADDDDDVCHDGWQRGRGVFARADFKKGDVVASVPYAACIGTAGLRSVVGSGKPPPFDGATPAECLAWQLFQIVGDERWAPYVDALPATIDAPCSGCWDHGEIAELQIGDAIASVAVALGKDLKSARRVVVIVEGDDCDDDEKKKKTHERWLWALSCVRSRAIGLTPEGGGAKQVMLVPLVDMLNHAHEDASVAWSSAIDDDDVDADESKSKSKTKTKTKTKTKTKTDATEPPPAGGRVTLVARRDIAAGEELLITYSEKSPTDPFTLRMGFVGGHNPHDSVQIFVNLPHAAGWYADTFKSEGGEDLVDRAVAMHVAEQIEASIRTFAPEESAPRLGYGGQCSEYLVTMFERFNKEVAPEEDPHALAAHAVRLRCEELLLSYPTNLAEDMELLDAPEGSSSRRFKLAVEFRLRKKAILQHMLMAAEDVAEEEAALAAAAKAENGAGGGKGRGREKEKEKKKGEGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSW9</accession>
    <name>C1MSW9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_57856</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058394.1">
        <property type="nucleotide sequence ID" value="XM_003058348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSW9"/>
    <dbReference type="GeneID" id="9683841"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57856"/>
    <dbReference type="eggNOG" id="KOG4118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CDQKGAA"/>
    <dbReference type="OrthoDB" id="73348at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045230">
        <property type="entry name" value="MBS1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21213">
        <property type="entry name" value="GEO09665P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21213:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="71" mass="7698" checksum="87B1BF3183A81905" modified="2009-05-26" version="1">MARGNAKANAQEKNAKKNAGKKEAKSDLKARAAAFKASCPICAAQLINYNMMKVHYEAKHPKETCPPPPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT79</accession>
    <name>C1MT79_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68083</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058440.1">
        <property type="nucleotide sequence ID" value="XM_003058394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT79"/>
    <dbReference type="GeneID" id="9683878"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68083"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="307" mass="30950" checksum="0128C7CEAF6C9396" modified="2009-05-26" version="1">MELTWPSRSNPRSGDGVVPRKQTTIQFGRSNLTTATRLTPAAAPFALDALDDDQPSSLSLRTSSAVLNVGVSGPTPGSGSSHSAGSAGAPSDKNSARSAAGSRAISGSNPSGVARSNLAPSYDGSQNPGWPAFQYTSIASFARSLEPSNECGSKSSGVGGASAAAAGASADDAREDDARGDDDAGKTTAPPRVRMLVVDDATRHRGDARVHDARGVGRASGRALALAIAIARAAARSAAIGARGSGSRPGDATSRRVGGRSASTGTRASRRARADEKKVSGTSGAAAGTYEDARRTSRHHPSWRSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTK8</accession>
    <name>C1MTK8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_39803</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058509.1">
        <property type="nucleotide sequence ID" value="XM_003058463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTK8"/>
    <dbReference type="STRING" id="564608.C1MTK8"/>
    <dbReference type="GeneID" id="9684318"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39803"/>
    <dbReference type="OrthoDB" id="1680732at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045879">
        <property type="entry name" value="B561A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47281">
        <property type="entry name" value="OS09G0557700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47281:SF1">
        <property type="entry name" value="OS09G0557700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="8">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="162" mass="16853" checksum="E082453792B80126" modified="2009-05-26" version="1">MLSYSAVEDEDAGHMGCAHAYYGVATLLAGASQPLNAFLRADKPDAPDAATSTPRKRWEWTHRITGVGSLSFAFAAIVTGLDEAKERGAARGANVAGGAYAAWVVACVAATIALEANRYRERRGGGSGRNFVELSDMTEDGDGARFERAAARGGGVVLSSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTL9</accession>
    <name>C1MTL9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD synthase</fullName>
            <ecNumber evidence="2">2.7.7.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_47323</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.2" evidence="2"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058516.1">
        <property type="nucleotide sequence ID" value="XM_003058470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTL9"/>
    <dbReference type="STRING" id="564608.C1MTL9"/>
    <dbReference type="GeneID" id="9684322"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47323"/>
    <dbReference type="eggNOG" id="ENOG502QVVU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KESNIGM"/>
    <dbReference type="OrthoDB" id="414641at2759"/>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAD synthetase" evidence="10">
        <location>
            <begin position="117"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="335" mass="35053" checksum="CD2CB74653A4FD90" modified="2009-05-26" version="1">MALTRSARAAAARIVAAASETVSTNFERIAPAADGAKTIVALGKFDAMHRGHARLAAVAAGMGAPYLVSFGGMAEVLGWTPTLPVVATEDRERVCELWRAEGLVSRELREHAIPFAAIRRMSPEEFVKTLKDIGVGGVVAGRNYRFGFKAAGTADTLVDLGEKLDVDVSIVDLLPADIEEDFDCPGGCTPQVSSTRVRACLAAGDVEQCNALLGRPHRLVMSVDDVAADVSFDASDTEIAFALASARNQYPAPGVYAVRAAMREIVEIAGPEGDVRRGAPDANAKDGRASDARMTVSDADVVLDFGVEGVPRELSGGVGGGGGEWVVCVDIISRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTQ3</accession>
    <name>C1MTQ3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_58507</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059062.1">
        <property type="nucleotide sequence ID" value="XM_003059016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTQ3"/>
    <dbReference type="STRING" id="564608.C1MTQ3"/>
    <dbReference type="GeneID" id="9684800"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58507"/>
    <dbReference type="eggNOG" id="ENOG502RUZ6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="5">
        <location>
            <begin position="19"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="281"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="363" mass="39410" checksum="1F7A7356B8FD28D1" modified="2009-05-26" version="1">MTEPDPQPPERAPGTPAVDDDGEEILCRYCFDGPEEGTMLSGICACAGGQKHVHLDCLRRWQRMVLVSQPTHPAFYEDDVRHHKCNVCAANFNIPPPTRNELMQTFTGAEIAALVDEGCVIGSQRAFSDELERQLVSMPFFQRLVCGYRNWIKGVYLITGVTPDDGTVTLPIRSGDTLDQIRDRLLVGDATTDDDEGGGGGGGGGGGDGATERDLGLMVSGRRHVLVSVGGVTGDKESLRRALCAARAPVELKLSTGKEPDCGEDHVTAVNLARLVPLFPEEEEEEEDEDDDEEGNDAGVNLEEEEMEGAARGSDGSDDDMDAEEEEEGSEEEEEGSEDGDISEVRSIHWFPYDRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTY4</accession>
    <name>C1MTY4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphorylated adapter RNA export protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">RNA U small nuclear RNA export adapter protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_69404</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PHAX family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059403.1">
        <property type="nucleotide sequence ID" value="XM_003059357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTY4"/>
    <dbReference type="STRING" id="564608.C1MTY4"/>
    <dbReference type="GeneID" id="9684514"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69404"/>
    <dbReference type="eggNOG" id="KOG3948">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EPKESLM"/>
    <dbReference type="OrthoDB" id="498933at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006408">
        <property type="term" value="P:snRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1440">
        <property type="entry name" value="PHAX RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039047">
        <property type="entry name" value="PHAX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019385">
        <property type="entry name" value="PHAX_RNA-binding_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038092">
        <property type="entry name" value="PHAX_RNA-binding_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13135">
        <property type="entry name" value="CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13135:SF0">
        <property type="entry name" value="PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10258">
        <property type="entry name" value="PHAX_RNA-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Phosphorylated adapter RNA export protein RNA-binding" evidence="12">
        <location>
            <begin position="145"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="355"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH56535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="501" mass="50669" checksum="16872A7AE5A66745" modified="2009-05-26" version="1">MAEQVLAENDFEDDFSDIDMEELDSYLTSPPGVAGAADSPAESARAAARARLAARAAHGEESMSAQAAAEAAVESVGGGAAAVNDENAPPGAARRSVFSRLDAAGAKTPSARALAAKRKHLISPPGKFARRKGSNGAGVNAARAARDLCGDLGEPKESLMRRAIECIGIPMANDLAIEVGAIEGGGGQMTADGSRRRTPGGVFWALLKTKVAKEDWDFIFEEEREVQRERCRRRQRAKSLANSNATSLAGSPSFRGGVVGMKTPAADLISNKLAGAADAAGATPGSRAVTITAPARPSLAERINGNVVVAQNNANAADTPAPAAAMSRLGMFAPATTTPPGSWAALAKAAAAKPAPAPAPAATPKPALKVNTTTTKTPLSNTSSTASDEFAVLTPDNVLDASVTLGGASYAARAKAAAALDAKENAVRAAAAEIKAKAKLAAVKMAPPAPAQAPVAVDDWAEDAEAADDDAMDVEEKTATATATAGGWGSAAASFASMLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU20</accession>
    <name>C1MU20_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_40114</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059420.1">
        <property type="nucleotide sequence ID" value="XM_003059374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU20"/>
    <dbReference type="STRING" id="564608.C1MU20"/>
    <dbReference type="GeneID" id="9684574"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40114"/>
    <dbReference type="eggNOG" id="ENOG502S415">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1517790at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.110">
        <property type="entry name" value="Protein of unknown function DUF2237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018714">
        <property type="entry name" value="DUF2237"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37466">
        <property type="entry name" value="SLR1628 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37466:SF1">
        <property type="entry name" value="SLR1628 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09996">
        <property type="entry name" value="DUF2237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="271" mass="27781" checksum="FDD631A138C55344" modified="2009-05-26" version="1">MSASGSILRSGSKPKRSVSFEYLPTTYGAAPARDAPTAATFARASSSSSSAPSSTSSVASTTRALHHPSSVGRALTLVLGAVALLGAFVALATHHHTANAHARGAGEGVVALSAASAARLGVENDASSGSKNLLGGPLRPCSDATQATQTGIDRSGSCAWDPDDAGYHAVCVEMDAKFLSASATRDANDLSSVVKPGERWCVCAWAFASAVERDPKTMEGLELQCDGSNGKLRGVYESFIARKEALKSPSGREYEAGKALAAVDRLCPAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUE0</accession>
    <name>C1MUE0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_1816</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059481.1">
        <property type="nucleotide sequence ID" value="XM_003059435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUE0"/>
    <dbReference type="GeneID" id="9684618"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_1816"/>
    <dbReference type="eggNOG" id="KOG0061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RDANQTE"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF139">
        <property type="entry name" value="PROTEIN SCARLET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="514" mass="57162" checksum="40FE950105A431F4" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUE6</accession>
    <name>C1MUE6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_17707</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat RAPTOR family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059182.1">
        <property type="nucleotide sequence ID" value="XM_003059136.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MUE6"/>
    <dbReference type="GeneID" id="9684622"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17707"/>
    <dbReference type="eggNOG" id="KOG1517">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TEVCTND"/>
    <dbReference type="OrthoDB" id="10262360at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030307">
        <property type="term" value="P:positive regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029347">
        <property type="entry name" value="Raptor_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14538">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01547">
        <property type="entry name" value="YEAST176DUF"/>
    </dbReference>
    <dbReference type="SMART" id="SM01302">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Raptor N-terminal CASPase-like" evidence="6">
        <location>
            <begin position="44"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1228"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="686"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="842"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="693"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="733"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="860"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1320" mass="140003" checksum="39AEED8DA4C36D90" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUX2</accession>
    <name>C1MUX2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58965</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059576.1">
        <property type="nucleotide sequence ID" value="XM_003059530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUX2"/>
    <dbReference type="STRING" id="564608.C1MUX2"/>
    <dbReference type="GeneID" id="9684705"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58965"/>
    <dbReference type="eggNOG" id="ENOG502SSNT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YWKTSMA"/>
    <dbReference type="OrthoDB" id="497124at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="134" mass="15598" checksum="59139772982FD2E9" modified="2009-05-26" version="1">MRVHIKPRVQKDKWSLYWKTSMATKTLYLDEFDIDVDPEKTTGKELRALVAETIGHQPEKELCRLESFVEPWELACAPFPMHKGRELDDDKTLAENKITTEGADVICVRKELIAEGWKILQQDDEDSDTEEEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVC7</accession>
    <name>C1MVC7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_40403</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059350.1">
        <property type="nucleotide sequence ID" value="XM_003059304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVC7"/>
    <dbReference type="STRING" id="564608.C1MVC7"/>
    <dbReference type="GeneID" id="9685086"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40403"/>
    <dbReference type="eggNOG" id="KOG2386">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14502">
        <property type="entry name" value="RNA_5'-triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF17">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="158"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="313" mass="33184" checksum="63A056F2F1928354" modified="2009-05-26" version="1">MPPPPRPIDARGGETRDDDAAAAPSTSAAASDPAAAPPPSSTSPLRTSPLSATNVPTVLSKLRKWGDYASFGEPALPSKFIPMKTPLSPTLLREDTFENVLLLPNFLAEQRESRGRDVGLVIDLSNHDCLYGDGIPEGLERVHVRNVAKSVPDIACTSEVIAVASEFWSRRPNAFVAIHCAYGFNRTGFVLCCYLIEACGLSADDALASFAAARPPGVKHDRFKVALRRRYPTPGCAPVPRDDAGEDDGGDGDADRDGGDDGEVGSGGDGGGARGGEGESWRNETLDLDNVAELEEALVELEEERRASLDRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVT9</accession>
    <name>C1MVT9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bromodomain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_18656</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059808.1">
        <property type="nucleotide sequence ID" value="XM_003059762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVT9"/>
    <dbReference type="STRING" id="564608.C1MVT9"/>
    <dbReference type="GeneID" id="9685247"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18656"/>
    <dbReference type="eggNOG" id="KOG1474">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SHASQCE"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="3">
        <location>
            <begin position="38"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="129" mass="14759" checksum="24D81B026CC1BCD6" modified="2009-05-26" version="1">MKDFEKSHGAQAEWNKPLTSCARQWQRACEKLLHRLMQDKKKSWCFKEPVDPVGLGIPDYPVIIKHPMDLGTIETMLKKGEISAPDEFIALVRTVFRNAYVYNGTDDPSGVRDTAQKASLFFEKEIAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVY3</accession>
    <name>C1MVY3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_59555</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059831.1">
        <property type="nucleotide sequence ID" value="XM_003059785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVY3"/>
    <dbReference type="STRING" id="564608.C1MVY3"/>
    <dbReference type="GeneID" id="9685557"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59555"/>
    <dbReference type="eggNOG" id="KOG0371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NRIFCLH"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="5">
        <location>
            <begin position="135"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="37630" checksum="38261E16FA4AE4D5" modified="2009-05-26" version="1">MADMLNNPFAQLDAQIEGLLRGELVPEADVKVICEKTKEALMREENVVPVAAPVTVVGDIHGQFADLCEMMKIGGKAPDTNYLFLGDYVDRGYDSVETVCTVMAMKARSSISHRFPYDRVGVVNAARWPGRVTLLRGNHESRQITQVYGFYDECLRKYGNANVWTYITDVFDHLPLAATIDNEIFCPHGGLSPSLDTLDHVRELARTQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISEQFNHANGLNLIARAHQLVQEGYEWAHEKSVVTIFSAPNYCYRCGNQGAIMEVDENMNREFLQYDQFQRAVNPEARRKQQKLPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW58</accession>
    <name>C1MW58_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59635</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059866.1">
        <property type="nucleotide sequence ID" value="XM_003059820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW58"/>
    <dbReference type="STRING" id="564608.C1MW58"/>
    <dbReference type="GeneID" id="9685597"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59635"/>
    <dbReference type="eggNOG" id="KOG4599">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CEPNCRD"/>
    <dbReference type="OrthoDB" id="1621991at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37764">
        <property type="entry name" value="KETOSE/ALDOSE ISOMERASE, PUTATIVE (MOG1/PSBP/DUF1795-LIKE PHOTOSYSTEM II REACTION CENTER PSBP FAMILY PROTEIN)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37764:SF1">
        <property type="entry name" value="KETOSE_ALDOSE ISOMERASE, PUTATIVE (MOG1_PSBP_DUF1795-LIKE PHOTOSYSTEM II REACTION CENTER PSBP FAMILY PROTEIN)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="351" mass="36913" checksum="2027CEE5E4358A79" modified="2009-05-26" version="1">MRAAIAPAAPAARVRASSSASARPRDRPPSIAAATRRHRHRVVRASARDADADAAPSPPSSSRREALVSAITLALATTTRAFPARADDDAFAADASTSIEEDPIAPADADPPKRPAASSAAPPVRYKGDNWSVVVPGAYARKATEKPRRIYEQRIADCEPNCRDLQAKRTDETPLVARFGSDDGGEDVSVSVRGANTLKLTFLQIKDVREFGEAREAAPLFIPPGAKLLDASARIETSPSGVEKGYYTYDFEYGEGRVLLTAAVELGNVYLLGATAGGAEAWSRAESGFRRAAKSFKVGAEDNLNKERAGAGAGAGDENGAIELPGGTRAPGEDLNCRGPLPIFCSVEPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWN9</accession>
    <name>C1MWN9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ANK protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_70857</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059959.1">
        <property type="nucleotide sequence ID" value="XM_003059913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWN9"/>
    <dbReference type="STRING" id="564608.C1MWN9"/>
    <dbReference type="GeneID" id="9685398"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70857"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QFGSCAL"/>
    <dbReference type="OrthoDB" id="540955at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="166"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="356"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="460"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="509"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="552" mass="57911" checksum="57158B5A1748DDBA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWW1</accession>
    <name>C1MWW1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_18764</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059992.1">
        <property type="nucleotide sequence ID" value="XM_003059946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWW1"/>
    <dbReference type="STRING" id="564608.C1MWW1"/>
    <dbReference type="GeneID" id="9685149"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18764"/>
    <dbReference type="eggNOG" id="KOG4707">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GRRKNVW"/>
    <dbReference type="OrthoDB" id="10251781at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1900.20:FF:000001">
        <property type="entry name" value="50S ribosomal protein L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="entry name" value="Ribosomal protein L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_bL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_bL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_bL20_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="Ribosomal protein L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="125" mass="14422" checksum="7EFBC32CEC227832" modified="2009-05-26" version="1">MRVSQVLWISKKRVFELSKGFRGRAKNTIRIARIRVEKALQHATRHRRARAGEVRRNWIQQINAGAREHGLKYSELIHGLKEENIHMNRKMLSDLAINEPYSFKALVDTVKRMKGVPVVTAAGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX59</accession>
    <name>C1MX59_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_60038</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TAF9 family. CENP-S/MHF1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060635.1">
        <property type="nucleotide sequence ID" value="XM_003060589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX59"/>
    <dbReference type="GeneID" id="9685778"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60038"/>
    <dbReference type="OMA" id="PKFAQCL"/>
    <dbReference type="OrthoDB" id="1872155at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071821">
        <property type="term" value="C:FANCM-MHF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22919">
        <property type="entry name" value="HFD_CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029003">
        <property type="entry name" value="CENP-S/Mhf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980:SF0">
        <property type="entry name" value="CENTROMERE PROTEIN S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980">
        <property type="entry name" value="CORTISTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15630">
        <property type="entry name" value="CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="131" mass="14583" checksum="617D876F1E52364D" modified="2009-05-26" version="1">MASEEIDDLVLEGHGGAIHDPSHLDDPNAGKQEALAARLKCEIIKISEEAAKARKIRVSPMVAQCVTELTMDYAEHFAKDILAFSKHRKGKTIALEDVKLAIRKLPRVEASVEECLPEELRTKRPRQTTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXA7</accession>
    <name>C1MXA7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_1187</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAC14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060363.1">
        <property type="nucleotide sequence ID" value="XM_003060317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXA7"/>
    <dbReference type="STRING" id="564608.C1MXA7"/>
    <dbReference type="GeneID" id="9686097"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_1187"/>
    <dbReference type="eggNOG" id="KOG0212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QCYQHVS"/>
    <dbReference type="OrthoDB" id="5574975at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021841">
        <property type="entry name" value="VAC14_Fig4p-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11916">
        <property type="entry name" value="Vac14_Fig4_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="5">
        <location>
            <begin position="89"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein 14 C-terminal Fig4-binding" evidence="6">
        <location>
            <begin position="393"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="580" mass="61876" checksum="32BF828E6AE7BC25" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXB5</accession>
    <name>C1MXB5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60095</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060367.1">
        <property type="nucleotide sequence ID" value="XM_003060321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXB5"/>
    <dbReference type="GeneID" id="9685805"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60095"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="256" mass="24717" checksum="832C70C843F61727" modified="2009-05-26" version="1">MNPESVQAALAAAQMGMFGSNPATAAAAASRFTGGFNPFAAAFPGAFGSGGGATVAQPATSGDAPSTSGGAPAATTSAQPTSTAAAPPGFFPPNAAVDAGAGSAMTAAAPTPTPTPAVPNWASFMQMMGPMMGPAMAAMQQMQAQHAQQQQQQQQQQQQQLSAAAAFASMSQPGVDPAAAMQAAVAAMQAAMAGNNPPAADGGSGNDSGHDSGGSGGGSAPPSTHPVKEYLETGADGAKRFKVSNDAAQDRAGHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXH8</accession>
    <name>C1MXH8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60164</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060398.1">
        <property type="nucleotide sequence ID" value="XM_003060352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXH8"/>
    <dbReference type="GeneID" id="9685836"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60164"/>
    <dbReference type="OrthoDB" id="497320at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="141" mass="14580" checksum="0275A51F1CC6551F" modified="2009-05-26" version="1">MAWVEAPYITLDDIPDLRNGDAPLAMEDADWLRPMLDETVRHSELQVAERLSFACLQIAPASGEADLVKLANCRAIAMSTSHGLMDRLKLGQIVLDEQRNALRAKVALKGAFSSSSSGGGGGAEGDGEGDGGAGAASSGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXL4</accession>
    <name>C1MXL4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60203</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060419.1">
        <property type="nucleotide sequence ID" value="XM_003060373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXL4"/>
    <dbReference type="GeneID" id="9685857"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60203"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="157" mass="17323" checksum="B9509C64FC33FA0C" modified="2009-05-26" version="1">MPSSGVTGVAATIESEERWLVRRMRELRMKGEVLMHDRPPFDRPKTDSAAARAEATARERERTRAKTAAAKRAEKRREEDDDDDGGGGVDEYGPWVVDESEYRDAYSDPVPARPRPVVEDAAAEEKAGCDDDDDDDDDDDDDESSDSDASEAASADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY17</accession>
    <name>C1MY17_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_9155</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060796.1">
        <property type="nucleotide sequence ID" value="XM_003060750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY17"/>
    <dbReference type="STRING" id="564608.C1MY17"/>
    <dbReference type="GeneID" id="9685925"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9155"/>
    <dbReference type="eggNOG" id="KOG1790">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="APHCAET"/>
    <dbReference type="OrthoDB" id="2014006at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.370.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008195">
        <property type="entry name" value="Ribosomal_eL34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038562">
        <property type="entry name" value="Ribosomal_eL34_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018065">
        <property type="entry name" value="Ribosomal_eL34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10759">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01199">
        <property type="entry name" value="Ribosomal_L34e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01250">
        <property type="entry name" value="RIBOSOMALL34"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01145">
        <property type="entry name" value="RIBOSOMAL_L34E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="100" mass="11203" checksum="AB8E349ED04F121B" modified="2009-05-26" version="1" fragment="single">RRHCYATKSNKIRKLRLPGGQLGIQYVKKKTKGPQTPSGDHGRIHGIPRVAKQKYSNKHMAKNKKSVSRAYGGVLSGGAVRERVVRAFLVEEQKIVKKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYE0</accession>
    <name>C1MYE0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Eukaryotic translation initiation factor 3 subunit B</fullName>
            <shortName evidence="6 7">eIF3b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">eIF-3-eta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">eIF3 p110</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_59878</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="6">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the eIF-3 subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060268.1">
        <property type="nucleotide sequence ID" value="XM_003060222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYE0"/>
    <dbReference type="STRING" id="564608.C1MYE0"/>
    <dbReference type="GeneID" id="9685996"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59878"/>
    <dbReference type="eggNOG" id="KOG2314">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LWGGPQF"/>
    <dbReference type="OrthoDB" id="10250414at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12278">
        <property type="entry name" value="RRM_eIF3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000286">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03001">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011400">
        <property type="entry name" value="EIF3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034363">
        <property type="entry name" value="eIF3B_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036424">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="45"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR036424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="693" mass="78512" checksum="079722AE468136BA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZL5</accession>
    <name>C1MZL5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60773</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060974.1">
        <property type="nucleotide sequence ID" value="XM_003060928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZL5"/>
    <dbReference type="STRING" id="564608.C1MZL5"/>
    <dbReference type="GeneID" id="9686680"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60773"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THIKAWI"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="8"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="314" mass="32812" checksum="0C49BF61B9381879" modified="2009-05-26" version="1">MQAAVRLGNGLIMHQRDVPIPSPTEPGQVRVKVHAAGTNPVDYKLPKLVAGPIAGIDVAGVVDAVAPGAPPGAAFDVGDEVFGFATGGSVAEYALADASKLASKPETMTFVDAAAMPTAYVTSYQALFEHGEMRPGARVLIIGASGGCGLAACQLAAAGGAAEIVAVCSSRNAQLCADAGATEAFDYADDERMQELLTRRFDLVYDAASGSGAGEDYRGFGMDVLAEPRGRRVAINGGFGEWFATLTGWGRGERDRLMLTRQDGEELTKIVELLGGEPSPVIDRVFELDLSGVNLGFARQKSRRARGKIVIKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZX8</accession>
    <name>C1MZX8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_35078</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061297.1">
        <property type="nucleotide sequence ID" value="XM_003061251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZX8"/>
    <dbReference type="STRING" id="564608.C1MZX8"/>
    <dbReference type="GeneID" id="9686736"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35078"/>
    <dbReference type="eggNOG" id="KOG2575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FQVPPMH"/>
    <dbReference type="OrthoDB" id="4983at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042281">
        <property type="term" value="F:dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF1">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="566"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="576"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH54947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="589" mass="63678" checksum="441ADCB012A244C0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N094</accession>
    <name>C1N094_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50935</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061594.1">
        <property type="nucleotide sequence ID" value="XM_003061548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N094"/>
    <dbReference type="GeneID" id="9686795"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50935"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="213" mass="22564" checksum="EF5EB0F5E1A6A8F9" modified="2009-05-26" version="1">MGASGKLSGCCQPGKPCIHHGGLKSQTLSADVKPEAAAGSGRTGRVVLMDPSRTPAANPLFDPTENAKYGVDATAALKNVDIDELQAAADAATAREDAAFEALVLEKEQSGRIARGASFLTAKFALQSDPRFKAAKRRAEALYKAFVARRRREEEEEARAAAVAVAAASAAEEEEAPEEIPCEYDATFTDDDEEEAPDAKRPRVDDEADSGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0M0</accession>
    <name>C1N0M0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">adenine phosphoribosyltransferase</fullName>
            <ecNumber evidence="7">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_51070</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="7"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061411.1">
        <property type="nucleotide sequence ID" value="XM_003061365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0M0"/>
    <dbReference type="STRING" id="564608.C1N0M0"/>
    <dbReference type="GeneID" id="9687105"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51070"/>
    <dbReference type="eggNOG" id="KOG1712">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PMIAVEL"/>
    <dbReference type="OrthoDB" id="363185at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000004">
        <property type="entry name" value="Adenine phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050120">
        <property type="entry name" value="Adenine_PRTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002636">
        <property type="entry name" value="PRK02304.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11776">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11776:SF7">
        <property type="entry name" value="PHOSPHORIBOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="12">
        <location>
            <begin position="54"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH54041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="249" mass="26398" checksum="6A5DBB014ED4E987" modified="2009-05-26" version="1">MSPSVALPATKELGPKHFCLDQADDGVKTIAKSLPWYGPKYSPHDVPSFYDVSGITEDPAVFQLVIDFFVARYRAQGPENGPTHIAGFDARGFLFGPPIALALKLPFVMIRKAGKLPGVLVSSGKYVTEYSTDETVMRVGAISSGDRVVLIDDLIATGGTALAGFDLVDQLGASVHEFAAMVSLPFLDGVGKIHAYRDGKYVDVPCFTMVDDSSIGPEMCSDPPEGTPRMVSAEDAAATAAKIKAAKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0W6</accession>
    <name>C1N0W6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_51177</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cdt1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061465.1">
        <property type="nucleotide sequence ID" value="XM_003061419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0W6"/>
    <dbReference type="STRING" id="564608.C1N0W6"/>
    <dbReference type="GeneID" id="9686905"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51177"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071163">
        <property type="term" value="P:DNA replication preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030174">
        <property type="term" value="P:regulation of DNA-templated DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08767">
        <property type="entry name" value="Cdt1_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08674">
        <property type="entry name" value="Cdt1_m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1420">
        <property type="entry name" value="DNA replication factor Cdt1, C-terminal WH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045173">
        <property type="entry name" value="Cdt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032054">
        <property type="entry name" value="Cdt1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038090">
        <property type="entry name" value="Cdt1_C_WH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014939">
        <property type="entry name" value="CDT1_Gemini-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28637">
        <property type="entry name" value="DNA REPLICATION FACTOR CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28637:SF1">
        <property type="entry name" value="DNA REPLICATION FACTOR CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08839">
        <property type="entry name" value="CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16679">
        <property type="entry name" value="CDT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01075">
        <property type="entry name" value="CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDT1 Geminin-binding" evidence="4">
        <location>
            <begin position="111"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="509" mass="53697" checksum="D3F7595773EA1675" modified="2009-05-26" version="1">MAPPSQYGGNARGAMMARMAGATASGGSGTAPLTPVDVNRVVASGEAEPTAKRARADADVVVEDARAKASTREEDETTRASTATTTATATTTATTATAVPAPARWHSSLPLPPKYEVLDDAFVALAQIGPLLRKRGQASTADNVCENVEATTRRRCTLKTLREVEGVLPGTVGLSTRAPVHDGGALDPRRVRVDVEEGAPGARAPGAGAGASRKTGSGWFDDRRKKFRAALLELVGAHHDAFVAGLDDDGGGGGGGGGGGVEVDDDGVVTSWHPKYDPTTAPDPPAARVVGAESAVVGVDPAGAGAGVAEGAALPPAAAATRDTMRSGNGTAFSAGWKRDRSEMDARELEADDLSRVEIDAEAIAARKATLGEGAEAIDDADLATVMKREMMARHENDPATRAERARRRLYDLLPGLFDAVRSWFATRDKKTAPFADIVEQILRTTTKQCASREETERGLRVLAKNAEEWCVLWVSEFTGEELWRVKKVDTTKVRFVREKLVALKEDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1J2</accession>
    <name>C1N1J2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41760</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061567.1">
        <property type="nucleotide sequence ID" value="XM_003061521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1J2"/>
    <dbReference type="GeneID" id="9687271"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41760"/>
    <dbReference type="OrthoDB" id="567014at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="417" mass="45263" checksum="0CD84A5317FFBB24" modified="2009-05-26" version="1">MPPAPDHVVDVIEMLDDDSLAMDAAGGARSASRGGGATRARAAASALGALDETTGTATAAEEEETLAAATTTTTTTTTTTRAIFARTTNAPPNAAWVAPGDPIPRAPSPSAWNHHLRASVTATVDALWQERPPRLLTYSPSALHTLGWLPFLTSWRNLRVTAFASWTLHAQSACLVAWTAALHVTRGLGVPQSQQRHFCAIFSTSYLGSLSSFGVITTLVLGLFISLVVQRWWEVRTQYATMHSAIIDVAVAFTSSTRRIRRRARPDGDGEEVITFNTHDDDDSTVKEFLRLLNLTHVLFLSQAGDMEHTVDAAKALRGCSLARPWDWHAFAAKLSAVNASAGRVLTYLASQLPYTYVNLVSFVSHVYLFVLATWFGFMLSSGLNQLAVEGRGTTRLARPRLHWSPYDPVRVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1Q0</accession>
    <name>C1N1Q0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_35562</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062155.1">
        <property type="nucleotide sequence ID" value="XM_003062109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1Q0"/>
    <dbReference type="GeneID" id="9687394"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35562"/>
    <dbReference type="eggNOG" id="ENOG502RZ3E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TFIVIID"/>
    <dbReference type="OrthoDB" id="498023at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003832">
        <property type="entry name" value="DUF212"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31446">
        <property type="entry name" value="ACID PHOSPHATASE/VANADIUM-DEPENDENT HALOPEROXIDASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31446:SF29">
        <property type="entry name" value="ACID PHOSPHATASE_VANADIUM-DEPENDENT HALOPEROXIDASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02681">
        <property type="entry name" value="DUF212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="154" mass="15858" checksum="54395B95F6BB365F" modified="2009-05-26" version="1">MTADLSVFDNVGLVAAIIAVFVAQFLKPFAEWARTRRARPSLALASGGFPSSHSALVAALAAGTGCQVGLADPGFGCAVVLALVVMYDAMGVRRQAGRHAAAINSLVSGLPSDFARAIQEKPLREHIGHTPVQVLAGMGLGVFIGVACGKFVGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1T5</accession>
    <name>C1N1T5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Photosystem I assembly protein Ycf4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">YCF4</name>
        <name evidence="12" type="ORF">MICPUCDRAFT_28946</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Seems to be required for the assembly of the photosystem I complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Plastid thylakoid membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ycf4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062175.1">
        <property type="nucleotide sequence ID" value="XM_003062129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1T5"/>
    <dbReference type="STRING" id="564608.C1N1T5"/>
    <dbReference type="GeneID" id="9687409"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_28946"/>
    <dbReference type="eggNOG" id="ENOG502QWGG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MRIFRYG"/>
    <dbReference type="OrthoDB" id="1927442at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055035">
        <property type="term" value="C:plastid thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00437">
        <property type="entry name" value="Ycf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003359">
        <property type="entry name" value="PSI_Ycf4_assembly"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002712">
        <property type="entry name" value="PRK02542.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33288">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33288:SF4">
        <property type="entry name" value="PHOTOSYSTEM I ASSEMBLY PROTEIN YCF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02392">
        <property type="entry name" value="Ycf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH53887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="273" mass="29115" checksum="2CFA0C9444A3CEA9" modified="2009-05-26" version="1">MSALAAVRGAPAVAARAATAPSASSRRAPAGPRASLPARRAAVAGTPLAMISRGAASRRAASGSRRRVLTRADAVPESEGAGSMFESQFKKVANDSVMIDPVVGAKRFSNYFWAGVVSIGATGFLITGASSYIEHNLLFFLDASEIKFFPQGLVMSFYGVAGSLLATYLWLTINWDVGAGYNEFNKEEGIMRIFRYGFPGNNRRINLVSSLADVQAVRVEISDGVNPRRVVYVRCKGKSDIPLTRIGQPLTLAEVEKQAADLAKFLGVPIEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N223</accession>
    <name>C1N223_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48452</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062218.1">
        <property type="nucleotide sequence ID" value="XM_003062172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N223"/>
    <dbReference type="GeneID" id="9687657"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48452"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="197" mass="20409" checksum="26AAE9CE105EC6E7" modified="2009-05-26" version="1">MNYVGTTFAGEIAPIYVLVPAGSNAADTEALLGIGLTSSEEAGTKGGEIKAVAAMIAKGEVVLMLYDPVTKYKTATKFDTCEAADPVKLAKVAQKMRGQVPDPAAVDGKRLPLPVPKSGVALMAELDPEGAKRGAIAMEEDEARRAREREAEDSALEDGVTIVGSSSSSKKKKKREKATMSAAGGAADVGVESKVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1N229</accession>
    <name>C1N229_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_21165</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062221.1">
        <property type="nucleotide sequence ID" value="XM_003062175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N229"/>
    <dbReference type="STRING" id="564608.C1N229"/>
    <dbReference type="GeneID" id="9687660"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21165"/>
    <dbReference type="eggNOG" id="ENOG502QQ7V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PVVFYES"/>
    <dbReference type="OrthoDB" id="289942at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000007">
        <property type="entry name" value="Ribosomal RNA small subunit methyltransferase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00096">
        <property type="entry name" value="16S rRNA (cytidine(1402)-2'-O)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111:SF1">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="7">
        <location>
            <begin position="67"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="389" mass="41187" checksum="40CD80F508CC8898" modified="2009-05-26" version="1">MYDPSEYPDEEEEEEEEEEDDDAVAGDVVAAARRAAAAFASRKDDPGSPSPSQPSQPADDPALAPGLYLVGTPIGNLEDITLRALRVLRTADVVLAEDTRHTRRLLRAYDVDAAALTSYHAHNERSRRDGVMDRLRRGGAVALVSDAGTPAVADPGGDLAAACAAEGIRVVPIPGPCAPAAAVIAAGLGTARFTFAGFLPAKSGARRKQLEELRGAAVGTTVFFVPPHKLVATLEDAVAPGSRARALLFFFRRFSLVSSRLRLFFAPSHAAASPDVMSRRVAPAVHLSQVHEEFWRGTLADAVAEFTSRKPRGEITLVVETGGGESGGETTPLPVRPRLDRALREMLDDGESPSEASKRAVRELGAKRKEAYAAALRLAGKTGGVDADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N270</accession>
    <name>C1N270_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_48467</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062239.1">
        <property type="nucleotide sequence ID" value="XM_003062193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N270"/>
    <dbReference type="STRING" id="564608.C1N270"/>
    <dbReference type="GeneID" id="9687480"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48467"/>
    <dbReference type="eggNOG" id="KOG2248">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CEMVITA"/>
    <dbReference type="OrthoDB" id="206335at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000031">
        <property type="entry name" value="RNA exonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF157">
        <property type="entry name" value="SMALL RNA DEGRADING NUCLEASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="8">
        <location>
            <begin position="342"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="199"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="285"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="617"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="617"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="644"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="752" mass="79604" checksum="CEC8A86C3FC75AF6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2L7</accession>
    <name>C1N2L7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_41843</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061897.1">
        <property type="nucleotide sequence ID" value="XM_003061851.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N2L7"/>
    <dbReference type="GeneID" id="9687547"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41843"/>
    <dbReference type="eggNOG" id="KOG1810">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="566306at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056843">
        <property type="entry name" value="THADA-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019442">
        <property type="entry name" value="THADA/TRM732_DUF2428"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051954">
        <property type="entry name" value="tRNA_methyltransferase_THADA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14387:SF0">
        <property type="entry name" value="DUF2428 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14387">
        <property type="entry name" value="THADA/DEATH RECEPTOR INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10350">
        <property type="entry name" value="DUF2428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25150">
        <property type="entry name" value="TPR_Trm732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA (32-2'-O)-methyltransferase regulator THADA-like TPR repeats region" evidence="3">
        <location>
            <begin position="703"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2428" evidence="2">
        <location>
            <begin position="1193"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1245"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1311"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="651"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1252"/>
            <end position="1273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1454" mass="152478" checksum="AC650CA374C891F6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N354</accession>
    <name>C1N354_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Threonylcarbamoyladenosine tRNA methylthiotransferase</fullName>
            <ecNumber evidence="4">2.8.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">tRNA-t(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MICPUCDRAFT_29134</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>N(6)-L-threonylcarbamoyladenosine(37) in tRNA + (sulfur carrier)-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + (sulfur carrier)-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:37075"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="Rhea" id="RHEA-COMP:11092"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:74420"/>
            <dbReference type="EC" id="2.8.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylthiotransferase family. CDKAL1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.5" evidence="4"/>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062550.1">
        <property type="nucleotide sequence ID" value="XM_003062504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N354"/>
    <dbReference type="GeneID" id="9687990"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29134"/>
    <dbReference type="eggNOG" id="KOG4355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IASVLCH"/>
    <dbReference type="OrthoDB" id="1730074at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035598">
        <property type="term" value="F:tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12160:FF:000009">
        <property type="entry name" value="threonylcarbamoyladenosine tRNA methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.30.20:FF:000002">
        <property type="entry name" value="threonylcarbamoyladenosine tRNA methylthiotransferase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="entry name" value="Methylthiotransferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="entry name" value="tm_1862 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006466">
        <property type="entry name" value="MiaB-like_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01578">
        <property type="entry name" value="MiaB-like-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00089">
        <property type="entry name" value="MiaB/RimO family radical SAM methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11918">
        <property type="entry name" value="RADICAL SAM PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11918:SF45">
        <property type="entry name" value="THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01082">
        <property type="entry name" value="B12-binding_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="17">
        <location>
            <begin position="112"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="241"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="16">
        <location>
            <begin position="474"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="61"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00051661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH53369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="542" mass="58846" checksum="809AD68D5C5F4C10" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3E9</accession>
    <name>C1N3E9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52147</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062367.1">
        <property type="nucleotide sequence ID" value="XM_003062321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3E9"/>
    <dbReference type="GeneID" id="9687807"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52147"/>
    <dbReference type="OMA" id="SDAWFGW"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="140" mass="13661" checksum="76E55D85509E053A" modified="2009-05-26" version="1">MSVAASLARVPAARAPPRRRRVASRASSSSSSSSSHVASSSPASASVVDARGRSTVASSASARVAALTAAATATAAQAATSGESVSQVATSDAWFGWAFIPGGPVLGPALLCAGFILLQAAYEKATGTGPSGKGDGSKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3F7</accession>
    <name>C1N3F7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52155</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062602.1">
        <property type="nucleotide sequence ID" value="XM_003062556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3F7"/>
    <dbReference type="GeneID" id="9688042"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52155"/>
    <dbReference type="OMA" id="WITSPNT"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="464"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="752"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="472"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="525"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="573"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="592"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="756"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="784"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="981" mass="106107" checksum="DF5BE50F2A616E4D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N400</accession>
    <name>C1N400_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52358</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062460.1">
        <property type="nucleotide sequence ID" value="XM_003062414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N400"/>
    <dbReference type="STRING" id="564608.C1N400"/>
    <dbReference type="GeneID" id="9688146"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52358"/>
    <dbReference type="OrthoDB" id="2122982at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034517">
        <property type="term" value="P:ribophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040040">
        <property type="entry name" value="ATG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222:SF1">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="225" mass="24241" checksum="794B4770450F2396" modified="2009-05-26" version="1">MRVIVAHSGETVELECDADTRVETVATALAAATGVDVADQLVVFAGRRLESSETLGAHELPTAAEPPPPPPVDDDAATTPHPKPSHVFMYMKSLLRPEATAPPVPPMVAVAVEASPPPPPPPPPATTAAAADHPLDASPSPLARALPDYERDFRAHAQRASSFARAMRRRFEHCERLILETHAMALAVDAVAENVDAHFSYIARRQVRSIHWFPYDRVGVVNVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N438</accession>
    <name>C1N438_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42320</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062725.1">
        <property type="nucleotide sequence ID" value="XM_003062679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N438"/>
    <dbReference type="STRING" id="564608.C1N438"/>
    <dbReference type="GeneID" id="9687919"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42320"/>
    <dbReference type="eggNOG" id="KOG2491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TTQGHIP"/>
    <dbReference type="OrthoDB" id="498733at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021861">
        <property type="entry name" value="THO_THOC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265:SF0">
        <property type="entry name" value="HPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265">
        <property type="entry name" value="THO COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11957">
        <property type="entry name" value="efThoc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="621"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="664" mass="71430" checksum="19C0CBAF1CE10407" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N439</accession>
    <name>C1N439_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52399</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062479.1">
        <property type="nucleotide sequence ID" value="XM_003062433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N439"/>
    <dbReference type="GeneID" id="9688166"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52399"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="450"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="535"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="562" mass="58467" checksum="9FE3FC44CF438AC9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4A2</accession>
    <name>C1N4A2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Divalent Anion:Na+ symporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CitT3</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_45892</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062963.1">
        <property type="nucleotide sequence ID" value="XM_003062917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4A2"/>
    <dbReference type="STRING" id="564608.C1N4A2"/>
    <dbReference type="GeneID" id="9688403"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45892"/>
    <dbReference type="eggNOG" id="ENOG502QQ8W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HYFFASQ"/>
    <dbReference type="OrthoDB" id="1695362at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015140">
        <property type="term" value="F:malate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030676">
        <property type="entry name" value="CitT-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42826">
        <property type="entry name" value="DICARBOXYLATE TRANSPORTER 2.1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1001">Plastid inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="458" mass="48391" checksum="25787B7A3F0C41AC" modified="2009-05-26" version="1">MSLTFAVATKTLSFQDGLAALTNEVIWLIVVATFFARAFVKTGFGDRLGLSFVRAFGKNTLSLAFGMQAAECVLSPAMPSTTARAAGVFVPIINSLDERTRAFLTGQQLQGGNASSTLLLSAAAQNFLCVQLAAAQGVTFANPFAEWFVAASVPCVLSLLATPLVHYAIDPPELKDTPEAPKAAAARLERMGALSAAEARSSITLLPIRPRSRGERRSLRTFSPGASLRPHHGFNPDTPRRLLTPTDAFQLHPDTRMVGGLGVTVFLWIFGSTLGISAALAAMIGLCILICAGVLTWDDALEQKGAWDTLLWFAILISMSSALNALGVVGYFAGAVSSSLVAANVSWGAAFGALHLGYYLMHYFFASQSAHVGALYPAFLAMMISSGAPPALAALTLAFNTNLFGGLTHYASGQSAVYFGSGHLPLATLWKQGAYMSVVNAVVFGVVGMAWWKVVGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4V6</accession>
    <name>C1N4V6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_42493</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062859.1">
        <property type="nucleotide sequence ID" value="XM_003062813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4V6"/>
    <dbReference type="STRING" id="564608.C1N4V6"/>
    <dbReference type="GeneID" id="9688503"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42493"/>
    <dbReference type="eggNOG" id="KOG0007">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HAYYRHR"/>
    <dbReference type="OrthoDB" id="447637at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01800">
        <property type="entry name" value="Ubl_SF3a120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000002">
        <property type="entry name" value="Splicing factor 3A subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000001">
        <property type="entry name" value="Splicing factor 3a, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045146">
        <property type="entry name" value="SF3A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022030">
        <property type="entry name" value="SF3A1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035563">
        <property type="entry name" value="SF3As1_ubi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316">
        <property type="entry name" value="SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316:SF1">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12230">
        <property type="entry name" value="PRP21_like_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00648">
        <property type="entry name" value="SWAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SURP motif" evidence="9">
        <location>
            <begin position="52"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="SURP motif" evidence="9">
        <location>
            <begin position="167"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="665"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="502"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="515"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="726" mass="75369" checksum="349B507D96DB370C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5V3</accession>
    <name>C1N5V3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_4690</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063221.1">
        <property type="nucleotide sequence ID" value="XM_003063175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5V3"/>
    <dbReference type="STRING" id="564608.C1N5V3"/>
    <dbReference type="GeneID" id="9688869"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4690"/>
    <dbReference type="eggNOG" id="KOG0600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YLVFNFC"/>
    <dbReference type="OrthoDB" id="28397at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF397">
        <property type="entry name" value="OS11G0242500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="313" mass="34094" checksum="623406FCC0768AC2" modified="2009-05-26" version="1" fragment="single">LAKVGQGTFSRVYKASDLNEGGEPCALKEIRLERADKDTLSLVAREIMMLRKLGDHDNVVNLRAIAVDSNDAAAIYLVFEYLPHDLAGLMSSRASRMREKKKGGGGGGGDDDDDGGDVAAGRVLSPGEVKHVAKQLLKALAHCHAAGGMHRDVKCSNLLVDDTGDVKLADFGLSRTPRDAEPLTNHVVTLWYRPPELLLGARRYDSKVDVWSAGCVLAELLWGEPILPGRTEVEQLHLIFKLVGSEGSARLAEKCKGFAPTSKVKEYPRALEDRFGVLTERFDANALDLVSRLLSLDPDDRPTAAEAARHPYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5X8</accession>
    <name>C1N5X8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_53084</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063441.1">
        <property type="nucleotide sequence ID" value="XM_003063395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5X8"/>
    <dbReference type="STRING" id="564608.C1N5X8"/>
    <dbReference type="GeneID" id="9688880"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53084"/>
    <dbReference type="eggNOG" id="KOG2537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WEAYATK"/>
    <dbReference type="OrthoDB" id="1928at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004610">
        <property type="term" value="F:phosphoacetylglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049022">
        <property type="entry name" value="AMG1_III"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955:SF1">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21404">
        <property type="entry name" value="AMG1_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="3">
        <location>
            <begin position="63"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="4">
        <location>
            <begin position="407"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="671" mass="69689" checksum="8AB2C30866E6D084" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N698</accession>
    <name>C1N698_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_22291</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063495.1">
        <property type="nucleotide sequence ID" value="XM_003063449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N698"/>
    <dbReference type="STRING" id="564608.C1N698"/>
    <dbReference type="GeneID" id="9688741"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22291"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EFRYFMI"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="15"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="51"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="88"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="124"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="161" mass="18026" checksum="4F6B3BE8E275074C" modified="2009-05-26" version="1">MVLTEKVAGAGLSEEQCAEFKEAFAIFDKDGDGTITIKELGVVMRSLGQNPTESELQDMINEVDESGDGELDFPEFLLLMSNRMKDNGSEDELVEAFKVFDRDGDGSVSVDELMTIMTMLGERLTREEVETMIRDADKDEDGELNFEEFKSIWFNSVALNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6G8</accession>
    <name>C1N6G8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Intraflagellar transport protein 140</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">IFT140</name>
        <name evidence="11" type="ORF">MICPUCDRAFT_42853</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063335.1">
        <property type="nucleotide sequence ID" value="XM_003063289.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N6G8"/>
    <dbReference type="GeneID" id="9688970"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42853"/>
    <dbReference type="eggNOG" id="KOG3617">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="APESHAW"/>
    <dbReference type="OrthoDB" id="10258787at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056155">
        <property type="entry name" value="Beta-prop_IFT140_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056168">
        <property type="entry name" value="TPR_IF140/IFT172/WDR19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056156">
        <property type="entry name" value="TPR_IF140_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722">
        <property type="entry name" value="IFT140/172-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722:SF7">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23385">
        <property type="entry name" value="Beta-prop_IFT140_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24762">
        <property type="entry name" value="TPR_IF140-IFT172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24760">
        <property type="entry name" value="TPR_IF140_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT140 second beta-propeller" evidence="8">
        <location>
            <begin position="449"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="IF140/IFT172/WDR19 TPR" evidence="10">
        <location>
            <begin position="764"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="domain" description="IF140/IFT172/WDR19 TPR" evidence="10">
        <location>
            <begin position="1137"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="domain" description="IF140 C-terminal TPR" evidence="9">
        <location>
            <begin position="1186"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="66"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="611"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1371"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1385"/>
            <end position="1395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH52471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1395" mass="147644" checksum="0B49D3C0BD38D68D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N722</accession>
    <name>C1N722_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_22690</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063656.1">
        <property type="nucleotide sequence ID" value="XM_003063610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N722"/>
    <dbReference type="STRING" id="564608.C1N722"/>
    <dbReference type="GeneID" id="9689269"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22690"/>
    <dbReference type="eggNOG" id="ENOG502S81M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ECTEHKA"/>
    <dbReference type="OrthoDB" id="361870at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="entry name" value="Ribosomal protein L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_bL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_bL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="Ribosomal_bL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001764">
        <property type="entry name" value="PRK00504.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001860">
        <property type="entry name" value="PRK00595.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L33, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL33C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="62" mass="7354" checksum="9AAAC60A8051CEF4" modified="2009-05-26" version="1" fragment="single">ASKKKDVRLTITLECTEQKESGVAGMSRYMTQKNRRNTSGRLELMKYNPYLRKHTLHRELKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7A2</accession>
    <name>C1N7A2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_53612</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DExH box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063862.1">
        <property type="nucleotide sequence ID" value="XM_003063816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7A2"/>
    <dbReference type="STRING" id="564608.C1N7A2"/>
    <dbReference type="GeneID" id="9689303"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53612"/>
    <dbReference type="eggNOG" id="KOG0920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000526">
        <property type="entry name" value="DExH-box ATP-dependent RNA helicase DExH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF99">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="432"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="55"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="101"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="143"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="329"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00060772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="680" mass="75075" checksum="F0DA2670185AF826" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7E5</accession>
    <name>C1N7E5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53663</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063721.1">
        <property type="nucleotide sequence ID" value="XM_003063675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7E5"/>
    <dbReference type="GeneID" id="9689327"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53663"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="115" mass="13368" checksum="DD21AFA4FBF61C27" modified="2009-05-26" version="1">MRRRKSLRIGVHHVNAVVWEPVYRTRLIGEIFALFVVVVVFAFFAFFAFASQQSLRVRERARRGRAPVVVHVDGLERHVDVLERVRESRARESTRGGGRDVRVVVVTLRAVLYER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7F5</accession>
    <name>C1N7F5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53676</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063727.1">
        <property type="nucleotide sequence ID" value="XM_003063681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7F5"/>
    <dbReference type="STRING" id="564608.C1N7F5"/>
    <dbReference type="GeneID" id="9689168"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53676"/>
    <dbReference type="OMA" id="RDANDSM"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="2">
        <location>
            <begin position="551"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="507"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="672" mass="70615" checksum="3FBB66BA0CFF93B9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7P2</accession>
    <name>C1N7P2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53776</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063941.1">
        <property type="nucleotide sequence ID" value="XM_003063895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7P2"/>
    <dbReference type="GeneID" id="9689382"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53776"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="533"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="746" mass="78616" checksum="6C99100D1BF09135" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N808</accession>
    <name>C1N808_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43224</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063999.1">
        <property type="nucleotide sequence ID" value="XM_003063953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N808"/>
    <dbReference type="STRING" id="564608.C1N808"/>
    <dbReference type="GeneID" id="9689440"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43224"/>
    <dbReference type="OMA" id="HEGYMLE"/>
    <dbReference type="OrthoDB" id="498886at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044200">
        <property type="entry name" value="At5g03900-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47380">
        <property type="entry name" value="OS02G0533000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47380:SF4">
        <property type="entry name" value="OS02G0533000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="537" mass="58107" checksum="50D0C663D3792FF0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8L8</accession>
    <name>C1N8L8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54138</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064288.1">
        <property type="nucleotide sequence ID" value="XM_003064242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8L8"/>
    <dbReference type="GeneID" id="9689549"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54138"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="100" mass="9936" checksum="9ECD4957C43D9B4A" modified="2009-05-26" version="1">MCGVAVVSKAKANEQEAAAKLVAAREEEYGGSGGDRTGGEGGATIAARRTSVDIGTEGGAVAILNLSPGPGAGGAKAGAYRDLEMESVDEEGRASFANHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8M6</accession>
    <name>C1N8M6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Papain family cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_66431</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064294.1">
        <property type="nucleotide sequence ID" value="XM_003064248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8M6"/>
    <dbReference type="STRING" id="564608.C1N8M6"/>
    <dbReference type="GeneID" id="9689735"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66431"/>
    <dbReference type="eggNOG" id="KOG1543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HTYEAIN"/>
    <dbReference type="OrthoDB" id="190265at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000117">
        <property type="entry name" value="Probable papain cysteine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025661">
        <property type="entry name" value="Pept_asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00640">
        <property type="entry name" value="THIOL_PROTEASE_ASN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="3">
        <location>
            <begin position="4"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="3">
        <location>
            <begin position="294"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="553" mass="59974" checksum="22B054E551B0C65B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8P6</accession>
    <name>C1N8P6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54194</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064483.1">
        <property type="nucleotide sequence ID" value="XM_003064437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8P6"/>
    <dbReference type="STRING" id="564608.C1N8P6"/>
    <dbReference type="GeneID" id="9689753"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54194"/>
    <dbReference type="eggNOG" id="ENOG502SBK5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="196" mass="21817" checksum="2DEA6DCFF8813B9D" modified="2009-05-26" version="1">MRPTLEADGNVACAIFSHLEDPRDRIALAAVSRVFRDAEKSDASLPVALGALKRHGDRFLYSSYATAVYWYRKGCDRGDAACMHAIGHCYRYPMSSDVLAKDMTKAVEWTKKASELGHAKATGALGLLYENGKGVDKDEAKAFELYVKAAELGDSWTAHRLVPYYEYGLCGVAVDKKEAQKWRDWLEAELRSTNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8U4</accession>
    <name>C1N8U4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54243</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064332.1">
        <property type="nucleotide sequence ID" value="XM_003064286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8U4"/>
    <dbReference type="GeneID" id="9689773"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54243"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="76" mass="7946" checksum="21DBECC024B2C640" modified="2009-05-26" version="1">MLRRLATNSARALLNATGASAPPPLASSTAAFHGSAPSRVGQVLVHMSGLDCGEIFSKTHKARIHHTGSHTIAFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9J3</accession>
    <name>C1N9J3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Guanosine nucleotide diphosphate dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_37124</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064630.1">
        <property type="nucleotide sequence ID" value="XM_003064584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9J3"/>
    <dbReference type="STRING" id="564608.C1N9J3"/>
    <dbReference type="GeneID" id="9690071"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37124"/>
    <dbReference type="eggNOG" id="KOG1439">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PAMDFVM"/>
    <dbReference type="OrthoDB" id="9446342at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.405.10:FF:000011">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="447" mass="49477" checksum="B4E7CE962DF17F98" modified="2009-05-26" version="1">MDQDYDAIILGTGLKECLLAGLLSVEGMKILHMDRNSYYGGESASLNLRQLWEKFRPGEPEPTHYGRWQDWAFDMVPKFMMGNGLLVRTLVHTSVHNYLQFKAVDGSYVVKGGKTYKVPATDMDALKSSLMGMFEKRRARSFFMYVQDYDETKPDTTKGHNLNVMTSRELFAKFGLQDGTVEFIGHALALNVDDAYLDRPALKMVKAVKLYEESLARFNTGSPYIYPLYGLGELPQGFARLSAVYGGTYMLAKPDVEVTYDPETKRATGVTSEGESARAKFVVGDPSYFPGKTRRIGRVVRAICILSHPIPNCGDAHSVQIILPQAQTGRQSDMYVFGCSWAHNVCAKGKYLAFVSTTVETANPHLEIEPGLALLGASPFVLFFINVTDVMTPIADGKEDGCFISAGYDATTHFESTVLDVLDMYTRITGKTLDLSEKDPAAAAAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9P2</accession>
    <name>C1N9P2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54564</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH50982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064648.1">
        <property type="nucleotide sequence ID" value="XM_003064602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9P2"/>
    <dbReference type="GeneID" id="9690211"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54564"/>
    <dbReference type="OMA" id="AEMFSWA"/>
    <dbReference type="OrthoDB" id="10445082at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46732">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE LA (LON) DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46732:SF8">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE LA (LON) DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="381" mass="41270" checksum="AEB871328BB3F2C6" modified="2009-05-26" version="1">MASSTLAARTATTLASSSWASSPRRVLKDRRSPRERGRMGTSVTPRRRRDGATSIAARSSAPDDDDAPPPPPSVASSPSRWTGPPVNRLDEQAARERVMRLATTTTQGAGALEAIQGCLSSMPGCPLDTVALNLIETRWVVAFDALANAPRRPGDPPFCFGITHPALTPAKTPPGEDPIPPKEGDVGLVCRMVDAYHDNKEERLYVTSQVVGRFRVDRVVTDGNPFFVAETSQARSYSHWSPYELVLDQVPEDDEGAKALAEEEADVWRLLKQLETLSAKTKEGDGAQIDYDMRRCSPDPKERPPWDADPPAPERRAEMFSWAVTRRLGLEPREHLDAVRTTHTSARLAQVKSALTEGVNYLAAVSALQGAEGGGEGGGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA22</accession>
    <name>C1NA22_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="4">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_45108</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="4"/>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064713.1">
        <property type="nucleotide sequence ID" value="XM_003064667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA22"/>
    <dbReference type="STRING" id="564608.C1NA22"/>
    <dbReference type="GeneID" id="9690154"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45108"/>
    <dbReference type="eggNOG" id="KOG1557">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WRAVITI"/>
    <dbReference type="OrthoDB" id="36455at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00948">
        <property type="entry name" value="FBP_aldolase_I_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000140">
        <property type="entry name" value="Fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000741">
        <property type="entry name" value="FBA_I"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033379">
        <property type="entry name" value="FrucBisAld_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11627">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00274">
        <property type="entry name" value="Glycolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="350" mass="36543" checksum="B54DAA03C86E9F19" modified="2009-05-26" version="1">MSSPHATELVATARALCAPGKGVLAADESTGTIGKRFATIAVENVEPNRRAYRELLFTTPGFETFCSGVITFEETFAQSAADGTTFVDVLASKGVLVGVKVDTGVVPLHGGLDGETATQGLDGLDARCAGYYARGARFAKWRAVLSIDRASGKPSDLCVRANADALARYASICQKNGLVPIVEPEILTDGAHDVETSAAVTERVLAAVFKSLSDHGVMLEARRTGTILKPNMATAGADAGDGGASTEDVARLTVRALQRVVPPAVPGILFLSGGQSEEEATAHLNAMNKARSISHWFPYDPPWALSFSYGRALQSSVLKAWRGDAANVAAAQEALLARGTANSKAALGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRD0</accession>
    <name>C1KRD0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="23 25">Photosystem II protein D1</fullName>
            <shortName evidence="23">PSII D1 protein</shortName>
            <ecNumber evidence="23">1.10.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="23">Photosystem II Q(B) protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="primary">psbA</name>
        <name evidence="27" type="ORF">MicpuC_chl30</name>
        <name evidence="28" type="ORF">MicpuC_chl37</name>
    </gene>
    <organism evidence="27 29">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="27"/>
    <reference evidence="29" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="29">CCMP1545</strain>
        </source>
    </reference>
    <reference evidence="27" key="2">
        <citation type="submission" date="2009-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Micromonas genome consortium"/>
                <person name="Foulon E."/>
                <person name="Lucas S."/>
                <person name="Glavina del Rio T."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Pitluck S."/>
                <person name="Zhou K."/>
                <person name="Grimwood J."/>
                <person name="Grigoriev I.V."/>
                <person name="Cuvelier M.L."/>
                <person name="Worden A.Z."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">CCMP1545</strain>
        </source>
    </reference>
    <reference evidence="27" key="3">
        <citation type="submission" date="2009-04" db="EMBL/GenBank/DDBJ databases">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.-H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Schnitzler Parker M."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F.X."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbD) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.</text>
    </comment>
    <comment type="function">
        <text evidence="22">This is one of the two reaction center proteins of photosystem II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>2 a plastoquinone + 4 hnu + 2 H2O = 2 a plastoquinol + O2</text>
            <dbReference type="Rhea" id="RHEA:36359"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:30212"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
            <dbReference type="EC" id="1.10.3.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="23">PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Psb30/Ycf12, at least 3 peripheral proteins of the oxygen-evolving complex and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="23">Plastid</location>
            <location evidence="23">Chloroplast thylakoid membrane</location>
            <topology evidence="23">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="23">C-terminally processed by CtpA; processing is essential to allow assembly of the oxygen-evolving complex and thus photosynthetic growth.</text>
    </comment>
    <comment type="PTM">
        <text evidence="23">Tyr-161 forms a radical intermediate that is referred to as redox-active TyrZ, YZ or Y-Z.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="23">2 of the reaction center chlorophylls (ChlD1 and ChlD2) are entirely coordinated by water.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="23">Herbicides such as atrazine, BNT, diuron or ioxynil bind in the Q(B) binding site and block subsequent electron transfer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 23 24">Belongs to the reaction center PufL/M/PsbA/D family.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.9" evidence="23"/>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRD0"/>
    <dbReference type="STRING" id="564608.C1KRD0"/>
    <dbReference type="OMA" id="CQWVTDT"/>
    <dbReference type="OrthoDB" id="494152at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016682">
        <property type="term" value="F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010242">
        <property type="term" value="F:oxygen evolving activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009772">
        <property type="term" value="P:photosynthetic electron transport in photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009635">
        <property type="term" value="P:response to herbicide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09289">
        <property type="entry name" value="Photosystem-II_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.85.10:FF:000002">
        <property type="entry name" value="Photosystem II protein D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.85.10">
        <property type="entry name" value="Photosystem II protein D1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01379">
        <property type="entry name" value="PSII_PsbA_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055266">
        <property type="entry name" value="D1/D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036854">
        <property type="entry name" value="Photo_II_D1/D2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000484">
        <property type="entry name" value="Photo_RC_L/M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055265">
        <property type="entry name" value="Photo_RC_L/M_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005867">
        <property type="entry name" value="PSII_D1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01151">
        <property type="entry name" value="psbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33149:SF12">
        <property type="entry name" value="PHOTOSYSTEM II D2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33149">
        <property type="entry name" value="PHOTOSYSTEM II PROTEIN D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00124">
        <property type="entry name" value="Photo_RC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00256">
        <property type="entry name" value="REACTNCENTRE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81483">
        <property type="entry name" value="Bacterial photosystem II reaction centre, L and M subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00244">
        <property type="entry name" value="REACTION_CENTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0007">Acetylation</keyword>
    <keyword evidence="11 23" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 23" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="5 27" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="16 23" id="KW-0157">Chromophore</keyword>
    <keyword evidence="13 23 25" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 23" id="KW-0359">Herbicide resistance</keyword>
    <keyword evidence="18 23 25" id="KW-0408">Iron</keyword>
    <keyword evidence="12 23" id="KW-0460">Magnesium</keyword>
    <keyword evidence="20 23" id="KW-0464">Manganese</keyword>
    <keyword evidence="19 23 25" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 23 25" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17 23" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6 23 25" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="21 23 25" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="27" id="KW-0934">Plastid</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="23" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="9 23 25" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 23 26" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 23 25" id="KW-0813">Transport</keyword>
    <feature type="initiator methionine" description="Removed" evidence="23">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5034769575" description="Photosystem II protein D1" evidence="23">
        <location>
            <begin position="2"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="propeptide" id="PRO_5034769573" evidence="23">
        <location>
            <begin position="345"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="23">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>ChlzD1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>pheophytin a</name>
            <dbReference type="ChEBI" id="CHEBI:136840"/>
            <label>D1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>[CaMn4O5] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:189552"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>[CaMn4O5] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:189552"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="23">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>PD1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>a quinone</name>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <label>B</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <begin position="264"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>a quinone</name>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <label>B</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>[CaMn4O5] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:189552"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>[CaMn4O5] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:189552"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>[CaMn4O5] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:189552"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>[CaMn4O5] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:189552"/>
        </ligand>
    </feature>
    <feature type="site" description="Tyrosine radical intermediate" evidence="23">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes free radical intermediate" evidence="23">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by CtpA" evidence="23">
        <location>
            <begin position="344"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="modified residue" description="N-acetylthreonine" evidence="23">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine" evidence="23">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00055838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="RuleBase" id="RU004331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="RuleBase" id="RU004332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="ACO50762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="ACO50766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="353" mass="38929" checksum="BC429DEAE7124071" modified="2009-05-26" version="1">MTATLERRENATVWGRFCSWITSTENRLYIGWFGVLMIPTLLTATSVFIVAFIAAPPVDIDGIREPVSGSLMYGNNIISGAVIPTSNAIGLHFYPIWEAASLDEWLYNGGPYQLIVCHFFIGVCSYMGREWELSFRLGMRPWIAVAYSAPVAAAAAVFIVYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANAGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAIWPVMGIWFTAMGISTMAFNLNGFNFNQSVVDSNGRVINTWADIVNRANLGMEVMHERNAHNFPLDLASVEAPSINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGS7</accession>
    <name>C1MGS7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_49924</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055373.1">
        <property type="nucleotide sequence ID" value="XM_003055327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGS7"/>
    <dbReference type="STRING" id="564608.C1MGS7"/>
    <dbReference type="GeneID" id="9680915"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49924"/>
    <dbReference type="OMA" id="PWIALEM"/>
    <dbReference type="OrthoDB" id="514844at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20917">
        <property type="entry name" value="DCAF15-NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032734">
        <property type="entry name" value="DCAF15_WD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14939">
        <property type="entry name" value="DCAF15_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDB1- and CUL4-associated factor 15 WD40 repeat-containing" evidence="2">
        <location>
            <begin position="31"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="634" mass="66053" checksum="154B964E71E4FD48" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGX6</accession>
    <name>C1MGX6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46152</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054853.1">
        <property type="nucleotide sequence ID" value="XM_003054807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGX6"/>
    <dbReference type="STRING" id="564608.C1MGX6"/>
    <dbReference type="GeneID" id="9681103"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46152"/>
    <dbReference type="eggNOG" id="KOG2625">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="508793at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010378">
        <property type="entry name" value="TRAPPC13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055427">
        <property type="entry name" value="TRAPPC13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13134">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13134:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06159">
        <property type="entry name" value="TRAPPC13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex subunit 13 N-terminal" evidence="2">
        <location>
            <begin position="23"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="500" mass="51034" checksum="BE3B002567817B16" modified="2009-05-26" version="1" fragment="single">MATPAPLAAATPVGGAAAPLPQAIQFRVMRTCAPTLKIDTPSRFALDDLGHPPCAPSTSTSSDVAFESRVDLGLRASRASGVTGTLCLPQAFGNVYLGETFAAYVSAINSSDRVVRDVSFKAELQTERRRVALFDNAAEAAPTMPPGATFDFTATHDLKELGAHTLVCGVVYTDADGERKYAPQYFKFNAANPLAVRTKVRPGRDGRALLEACIENATPAPLLLSRATFEPCAHLECDEIVPACVSGAGVVIPEGDPHRGEEGGGGGGGGGGGARDAAAAGGSGLGEGLPSLANRPLRVLSPQGGSTHFLFELRQRPDITVTSDTLGKLEIRWTGHNGEAGRLQTQQIVGSPRIGGKDVEVAFAHGAPPKTARVHAPLTLSCVVTNKTASATRALEVIAQPDSDVVGGGATGGGGGATGATGGATGGGGGVAGILVDGPQRIAIGALPPGGERRVELTCVPTLPGTRRLPIVSVAEARGDGDARGGRVFDQLARFEVLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH37</accession>
    <name>C1MH37_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bromodomain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_7119</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055426.1">
        <property type="nucleotide sequence ID" value="XM_003055380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH37"/>
    <dbReference type="GeneID" id="9680829"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7119"/>
    <dbReference type="eggNOG" id="KOG1845">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RISCIGM"/>
    <dbReference type="OrthoDB" id="567073at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045261">
        <property type="entry name" value="MORC_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23336:SF76">
        <property type="entry name" value="MORC S5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23336">
        <property type="entry name" value="ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="193" mass="20902" checksum="02D822FB3E830840" modified="2009-05-26" version="1" fragment="single">NATSHVWPLGALAELLDNAQDQECGATEVHVDVVNVAPGVPAITVQDDGVGMARANLHCMLSFGFSSKEHVVGNVGRFGIGFKSGSMRLANDALILTRREGQASVALLSTTFLNAIDADDILIPMFTWKVDESGGSGRRSYIADEPSNTTEWEENMAVIEEYTFLKSEAAVLEELDKIDTKTGTRIVLFNLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH76</accession>
    <name>C1MH76_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_46189</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054904.1">
        <property type="nucleotide sequence ID" value="XM_003054858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH76"/>
    <dbReference type="GeneID" id="9681244"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46189"/>
    <dbReference type="eggNOG" id="ENOG502S7VR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10265564at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="218" mass="23798" checksum="B3A8598C66D08AAC" modified="2009-05-26" version="1">MVSSLFSKAVFTMDTRQLPLSVVVFALSGFVSVANHAYKTSAFDHKAFVASFPATYGTKWRAGKSAAPVDVSAFAPVVLVTAAWALLYYAFLMDQSATAFVVLKDAKRKAAAEKKPTPTLADVKYGKYSKGARMRVADRTVGNYLEQSVPFLTSLWLHAAFVSPVNAAAIGWCWIAARFVYPWAYKRPFPAVFVSTLPSYACVVYLLGEVVRSVVALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI07</accession>
    <name>C1MI07_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_11308</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LanC-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055583.1">
        <property type="nucleotide sequence ID" value="XM_003055537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI07"/>
    <dbReference type="GeneID" id="9680936"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11308"/>
    <dbReference type="eggNOG" id="KOG2787">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YLHRANC"/>
    <dbReference type="OrthoDB" id="10257263at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031179">
        <property type="term" value="P:peptide modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04794">
        <property type="entry name" value="euk_LANCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020464">
        <property type="entry name" value="LanC-like_prot_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12736">
        <property type="entry name" value="LANC-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12736:SF7">
        <property type="entry name" value="LANC-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01951">
        <property type="entry name" value="LANCEUKARYTE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158745">
        <property type="entry name" value="LanC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR607822-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="135" mass="14522" checksum="A6E9EE78AE65C9A2" modified="2009-05-26" version="1" fragment="single">KLVQWCHGAGGFAPVLAHAISHPGPCVAPARAYHSPLCKTAEVVWRRGVLRKGCGLCHGVAGNGYAFLSVYRVTKDARSLARAKRFARYCAKHAVESSRDADRPSSLFEGLAGVVVFLADTLAPETSWFPGFELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI99</accession>
    <name>C1MI99_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50492</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055631.1">
        <property type="nucleotide sequence ID" value="XM_003055585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI99"/>
    <dbReference type="STRING" id="564608.C1MI99"/>
    <dbReference type="GeneID" id="9680348"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50492"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="118"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="353" mass="36795" checksum="03B3AA9DB839A058" modified="2009-05-26" version="1">MSSRLVAARAPTSLASSSASAAARRRRHAAATASSSTSAPSDVVGDRGVSSRRRALLAALALATAPVRPPRASAASAADALADARELYGAGGLEDAEAVLERAVAVADDRDLEASSKAALLKLLGDVRVDAYAYERAMRAYDAALEADPRGASASGAHFGRANALEGLAAAAATAAAATALYESAIDDYGACLELAKPGGAGPAVPLFERAQAYKRLERWDDARRDYAAAAVAFADARARKEQKIAEAQAAFATFETGDVAAARRQLETLSRQLYSSDVRAALVACYWVAGDAARAEDLWLSLCEMDASRCGNRRESEYADAGWLLERRKWTPGLAAGMGDFLALRPAAAAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIB0</accession>
    <name>C1MIB0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_50503</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055636.1">
        <property type="nucleotide sequence ID" value="XM_003055590.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9680844"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50503"/>
    <dbReference type="eggNOG" id="KOG0061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AMMELEW"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910260" evidence="10">
        <location>
            <begin position="23"/>
            <end position="1993"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="895"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="930"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="970"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1008"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1038"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1694"/>
            <end position="1717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1729"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1761"/>
            <end position="1782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1788"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1817"/>
            <end position="1836"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1842"/>
            <end position="1862"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1963"/>
            <end position="1985"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="538"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1348"/>
            <end position="1603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="414"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="531"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="835"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1188"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1296"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="535"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="557"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1212"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1299"/>
            <end position="1313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH60888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1993" mass="213055" checksum="8E9F5D173AF9D3A0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJD8</accession>
    <name>C1MJD8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_50902</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055814.1">
        <property type="nucleotide sequence ID" value="XM_003055768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJD8"/>
    <dbReference type="STRING" id="564608.C1MJD8"/>
    <dbReference type="GeneID" id="9681219"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50902"/>
    <dbReference type="eggNOG" id="KOG2771">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QHWPTSF"/>
    <dbReference type="OrthoDB" id="3180714at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF156">
        <property type="entry name" value="INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="153"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="236"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH61066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="354" mass="38444" checksum="1B0678AAEF7F550B" modified="2009-05-26" version="1">MADVALGEPTHVPATPPPVFELADVWTTRVDKRACSLLLKEACAEIPLPDALAHVKRVRKADDGDDRLRLVVCIASSSSSSSSFDDDRDVPDAARALVTRHALPPLERDTVPAHAPRTREQWEAWNARWPISWKKPMSHLAEPAESPSAADAETMRRWTREAIDDARRGGGGGCVIANAVVIVDPASGRVVARGRDATGGWRIRRRDGEDEDEEDARRHPLRHAVLDAIDAAASADLARDPPSSSPLPPPPPPPPGDDDDFGGVGEKRRRAPTASLAEMTAEIGRGYLCTGYDVYCAREPCVMCAMALTHSRVRRVIYAIPSARHGALGGGAYSLQKERTLNHHYDVYTFGVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJS4</accession>
    <name>C1MJS4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55075</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055871.1">
        <property type="nucleotide sequence ID" value="XM_003055825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJS4"/>
    <dbReference type="GeneID" id="9681431"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55075"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="136" mass="14107" checksum="7288765A4C79B624" modified="2009-05-26" version="1">MARTRSASSASASEVTMTYRPAAAREASDQSSARVTAASASTRSRRDRSSATTTTTTTDGADDRGGIVAGGPRVARERDARIIGTPPVLGALVLFIVVLVVVALLCVASPSARAMEVRSISNWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJW0</accession>
    <name>C1MJW0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55120</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055889.1">
        <property type="nucleotide sequence ID" value="XM_003055843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJW0"/>
    <dbReference type="STRING" id="564608.C1MJW0"/>
    <dbReference type="GeneID" id="9681442"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55120"/>
    <dbReference type="OrthoDB" id="528882at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="171" mass="17168" checksum="801CFC140174176E" modified="2009-05-26" version="1">MENDAGLCYKKCRDGFDGVGPVCWGEPPTGWVNCGMGAAVDKATCGSAIADMVLGPLEIIAFAASFGTSTAATAPAKAAAKAAKGAAKELAEQGTESLVKQVKKQVVETTGESMATGGGAQLVSSIGGLQKSPSTVDTLRKAMEIAALVDPTGVSSTVAAYAHDKCDKISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJW4</accession>
    <name>C1MJW4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cleavage stimulation factor-related WD40protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_71050</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055892.1">
        <property type="nucleotide sequence ID" value="XM_003055846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJW4"/>
    <dbReference type="STRING" id="564608.C1MJW4"/>
    <dbReference type="GeneID" id="9681647"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_71050"/>
    <dbReference type="eggNOG" id="KOG0640">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CGERSEN"/>
    <dbReference type="OrthoDB" id="513537at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF0">
        <property type="entry name" value="NOTCHLESS PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="482"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="133"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="659" mass="69811" checksum="BAA09E8A08FFEE58" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKQ0</accession>
    <name>C1MKQ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flagellar outer dynein arm light chain 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ODA-LC5</name>
        <name evidence="4" type="ORF">MICPUCDRAFT_24914</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056424.1">
        <property type="nucleotide sequence ID" value="XM_003056378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKQ0"/>
    <dbReference type="STRING" id="564608.C1MKQ0"/>
    <dbReference type="GeneID" id="9681354"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_24914"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DMWRIRE"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000527">
        <property type="entry name" value="Calmodulin-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00036">
        <property type="entry name" value="EF-hand_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="6"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="117"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="147" mass="16113" checksum="3F26CE987FECE2AE" modified="2009-05-26" version="1">MPLSQEEINGCREAFNKFDKDGSGTIDASELKATLNAVGQSPSDEEIFQMISQVDDDNSGEIEFSEFLKVIENQKVSAAQVSDETDTVEAFVALGGNTDKSGEISTEKLRTVVKEFGLTIDLDRLIREIDTDGSGKVDYEEFKAMMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKR6</accession>
    <name>C1MKR6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="4 11">2.7.7.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ADP-glucose pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ADG2A</name>
        <name evidence="13" type="ORF">MICPUCDRAFT_31569</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="4 11"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056043.1">
        <property type="nucleotide sequence ID" value="XM_003055997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKR6"/>
    <dbReference type="STRING" id="564608.C1MKR6"/>
    <dbReference type="GeneID" id="9681974"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31569"/>
    <dbReference type="eggNOG" id="KOG1322">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YRMDFSQ"/>
    <dbReference type="OrthoDB" id="1733332at2759"/>
    <dbReference type="UniPathway" id="UPA00152"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02508">
        <property type="entry name" value="ADP_Glucose_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04651">
        <property type="entry name" value="LbH_G1P_AT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000030">
        <property type="entry name" value="Glucose-1-phosphate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002772">
        <property type="entry name" value="PRK02862.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523:SF12">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE LARGE SUBUNIT 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25247">
        <property type="entry name" value="LbH_GLGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00808">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00810">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0750">Starch biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="12">
        <location>
            <begin position="69"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH59419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="502" mass="54603" checksum="D170F801DE4207DF" modified="2009-05-26" version="1">MIVNADARLVRCSAPSGLLGSRYSFRGSRLDPRRLLLRTARKSVPRAAALQTDENQTSTVISNSKSVAAVILGGGAGTRLYPLTKSRAKPAVPIGGAYRLIDVPMSNCLNSGISKMYILTQFNSVSLNRHLARTYNFGNGIMYGGSGFVEVLAATQTPGLGGKEWFQGTADAVRQYSWLFEDVKNKDVQDVVILSGDHLYRMDYMAFVDRHREVNADITIGCLPMDGERASDFGLMKIDKTGRITEFAEKPEGNDLLAMQVDTTVLGLSPEESQASPYIASMGIYVFKKSALISFLNSEYPKDNDFGGEIIPKAAADGYHVQAYLFKDYWEDIGTIKSFFEANLALAKHPPQFEFYDARAPIYTSPRFLPPAKIEKCHVKDAIISHGCSLADCCVENAIVGLRSQVGKGCKIERAMIIGADFYESEDQKAKVIASGGVPVGIGEGCTITNAIIDKNARIGKNCIITNASGIDDLEDEENGVYIRSGIVTILRNATIPDGTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKY6</accession>
    <name>C1MKY6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peroxisome biogenesis protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Peroxin-12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_25018</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056078.1">
        <property type="nucleotide sequence ID" value="XM_003056032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKY6"/>
    <dbReference type="STRING" id="564608.C1MKY6"/>
    <dbReference type="GeneID" id="9681743"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25018"/>
    <dbReference type="eggNOG" id="KOG0826">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QHYLARC"/>
    <dbReference type="OrthoDB" id="107372at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16451">
        <property type="entry name" value="mRING_PEX12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017375">
        <property type="entry name" value="PEX12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888:SF0">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038074">
        <property type="entry name" value="Peroxisome_assembly_p12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pex N-terminal" evidence="14">
        <location>
            <begin position="22"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH59454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="370" mass="40611" checksum="45637A370B5FFB2F" modified="2009-05-26" version="1">MQFPVNASQQRPTFFELVAADRLVSSLRSALVYSMRVLVSRRPSSSWILDREDECFAAFMTLVETHAFATSNGSMAEGFYGLQRTRWRGSRVRGRGGERDAVDGVTGVKKTRALTRTERALSVLTLVAVPYAREKLDRLHKRLLAHGGGTIARDAARALLRDDEEGEDEDGGVLLRLPSAYVRTPSSLASSTFVKTYPIVNALLEAATFAHWLSFLIDGGDTHDPILRFLGLKITRVSLIETSETRAALDAHRAIAFTFPDRLHLSIAVVAFKLAEWWYGTAEGVVERGSLLPSPPPPPLPPPALDGVGIAPRGRCPVCRRFIVDASTLACSGYVFCSECAFEHVQQVKSCPVTLIPSKNANVRRLFDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLH7</accession>
    <name>C1MLH7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55719</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056169.1">
        <property type="nucleotide sequence ID" value="XM_003056123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLH7"/>
    <dbReference type="GeneID" id="9681795"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55719"/>
    <dbReference type="OMA" id="CASIANR"/>
    <dbReference type="OrthoDB" id="498550at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="214" mass="24233" checksum="8ADA18C826718A34" modified="2009-05-26" version="1">MVPTPAVSVPCRDIFCTSTYARLRTNLGVARILTRRREHEVVASWHCRGTPRARNRRNKLFFCASIANRSRSASEILERAKRYTSDLTELGLTMPLIRRNVAGVKNDLKALKVYQEALDGIEPVDEDDWTRLELVLLDLNSLRLNKAEEELFWAERDGQIVSPIIDNAAGLSEKEKSEVGNIVANITMWSVQGAVWNALILLIIFITLVNFVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLQ9</accession>
    <name>C1MLQ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Intraflagellar transport protein IFT52</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">IFT52</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_32015</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056611.1">
        <property type="nucleotide sequence ID" value="XM_003056565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLQ9"/>
    <dbReference type="STRING" id="564608.C1MLQ9"/>
    <dbReference type="GeneID" id="9681611"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32015"/>
    <dbReference type="eggNOG" id="KOG3861">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NWNVEQN"/>
    <dbReference type="OrthoDB" id="10259368at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23683">
        <property type="entry name" value="IFT52_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039975">
        <property type="entry name" value="IFT52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055460">
        <property type="entry name" value="IFT52_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055458">
        <property type="entry name" value="IFT52_GIFT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12969:SF7">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12969">
        <property type="entry name" value="NGD5/OSM-6/IFT52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23352">
        <property type="entry name" value="IFT52_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23355">
        <property type="entry name" value="IFT52_GIFT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IFT52 GIFT" evidence="2">
        <location>
            <begin position="21"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="IFT52 central" evidence="1">
        <location>
            <begin position="298"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="457" mass="50309" checksum="F2A8CF0D8BDA8ABE" modified="2009-05-26" version="1">MRESSGNSRIGPQVQAGGPAILFSCTESEKYHPESNLSGFARWFRRLRATFRLATLTGPITAEKLEGIDILVSPQEKFSLSELETLKDFIHGGGAILFLCDEGGQPAMGTSIDYLLEEYGISTNGDVLVSTSRQTFFHPKEPLVFDGVPKRSILSKVDRIQRTLGSVISSGSNDSTFHFGDTSGDVGLTFVVPSGATLVVRKPAATILSSGKLAYPMQRPVCATWHGGGSRGQNKGRIAVLGSGKMATDYWFDREDNARVLDFIMQWLATDSKVNLYDLDAEDLEIGEYILLQDTVNLAGRPRSSLEEGDNKPKDFTVMFVGTVYVEDTDFVHETFELYNRLMVEKANLSLIAPQFECPLPPLQPSVFPPALSEPPPPALDLFDLELAFSTEQTRLANVFVQCTAGRSDDFAFFVREGSCLCGFTNDKKDSTTLSCKAQLAKIFCQLINFKMSEELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLR4</accession>
    <name>C1MLR4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_25397</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056614.1">
        <property type="nucleotide sequence ID" value="XM_003056568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLR4"/>
    <dbReference type="STRING" id="564608.C1MLR4"/>
    <dbReference type="GeneID" id="9681859"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25397"/>
    <dbReference type="eggNOG" id="KOG1040">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EDVKDCN"/>
    <dbReference type="OrthoDB" id="306690at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000017">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor 30 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045348">
        <property type="entry name" value="CPSF4/Yth1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102:SF24">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH59990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="195" mass="22248" checksum="25EFDFCEAC3EA123" modified="2009-05-26" version="1">MEDLEFQFDFENDLNADLEQPEEAPQSMPENARKNYRQTVCRHWLRGLCMKGNHCGFLHQFDKQRMPTCRFFAKYSECKEPDCPFKHSLEDVKDCNMFKLGFCIHGPNCRYRHPRSSSEHPSISDSALIGRPGHLHGAPSHLQRHHLDLTKQKSEQRTCRLVGGGAPPLPPGPPPSDVRVVQHLSKLPASHKSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM39</accession>
    <name>C1MM39_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_9493</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056870.1">
        <property type="nucleotide sequence ID" value="XM_003056824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM39"/>
    <dbReference type="STRING" id="564608.C1MM39"/>
    <dbReference type="GeneID" id="9682769"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9493"/>
    <dbReference type="eggNOG" id="KOG0907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CQLSNNF"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044193">
        <property type="entry name" value="TRL33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47571">
        <property type="entry name" value="THIOREDOXIN-LIKE 3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47571:SF1">
        <property type="entry name" value="THIOREDOXIN-LIKE 3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="77" mass="8625" checksum="AAE8D7EF81B13106" modified="2009-05-26" version="1" fragment="single">RDSLVVVKFGASWCTHCAEMLPEFGAASRAYPESHFVLADVDTLPDSAKDVRFTPTFTFYRKGKKIDEITKTTPRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMA5</accession>
    <name>C1MMA5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U1 small nuclear ribonucleoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">snRNP</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_56455</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057369.1">
        <property type="nucleotide sequence ID" value="XM_003057323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMA5"/>
    <dbReference type="STRING" id="564608.C1MMA5"/>
    <dbReference type="GeneID" id="9682336"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56455"/>
    <dbReference type="eggNOG" id="KOG0113">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GRTTKGW"/>
    <dbReference type="OrthoDB" id="4207594at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12236">
        <property type="entry name" value="RRM_snRNP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000132">
        <property type="entry name" value="Small nuclear ribonucleoprotein U11/U12 subunit 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034143">
        <property type="entry name" value="snRNP70_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022023">
        <property type="entry name" value="U1snRNP70_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF5">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12220">
        <property type="entry name" value="U1snRNP70_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="194"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="134"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="270"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="146"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="337"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="472" mass="52831" checksum="3A1A24037309D9EB" modified="2009-05-26" version="1">MLKQAPPSLGPPGAPLRPGLPPPPGAFVPGMRPPGMPGMMPGMMPGYGMPPGMPPGMMRPPGMGMGMGLRPMGPPGAMMGMRAAPGGAAGAHQTGLTPSLLALFVPRPPVEYMPAPAKPKKTQPMTGVAAYVDKFTDPADDPPPAPKEKKETKEEKKLRRRMAAEERNARALEEAIEKWDPKEDPKAKDSDPYKTLFVGRLSYDVDESKLRREFEQWGPVKSVRVVEDVETGKPRGYAFIEYNRESDMKTAYKQADGRRIENKRVVVDAERGRTVPDWKPRRLGGGLGRTRKGAKHENSLVSGRDQAYHSRDRPSEGDGYRGGGDDRRGGGYAPPGYDERGRDHPRGYDDRGRRDDRGRGGRDSRRGGYDDRGRDRDRSRDRAPRDRSRDRDRDRSRDRDRDRDSRRMDRDRDSRRSDRDRDRDRDRKRSRSRSRDDRDGGGRRRRDSGGFGAPPPPPPPPAEDGEMEEGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMA9</accession>
    <name>C1MMA9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="11">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_636</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="11"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056898.1">
        <property type="nucleotide sequence ID" value="XM_003056852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMA9"/>
    <dbReference type="STRING" id="564608.C1MMA9"/>
    <dbReference type="GeneID" id="9682811"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_636"/>
    <dbReference type="eggNOG" id="KOG0351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ICEYLHI"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18018">
        <property type="entry name" value="DEXHc_RecQ4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000772">
        <property type="entry name" value="ATP-dependent DNA helicase Q4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF108">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="35"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="232"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH58543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="676" mass="72224" checksum="B460D9ACCD6B1611" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMD6</accession>
    <name>C1MMD6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_4705</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057385.1">
        <property type="nucleotide sequence ID" value="XM_003057339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMD6"/>
    <dbReference type="STRING" id="564608.C1MMD6"/>
    <dbReference type="GeneID" id="9682824"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4705"/>
    <dbReference type="eggNOG" id="KOG0239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YERTRTW"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF28">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="6">
        <location>
            <begin position="5"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="82"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="346" mass="37151" checksum="8FB101B27403D79D" modified="2009-05-26" version="1" fragment="single">ELKGNIRVFLRVRPISAREEANGDVAAVSAVSALEAKIEGGKRYELDHVAGPSASQSEIFEEIEPLIRSCLDGYDVCVFAYGQTGSGKTYTMEGTPADRGITFRSLASLFREAESDYATSSYSFSCTMMEIYNDKVRDLLEPDAANPKPHDIRQGADGTPYVTDLERVNVSSTMDVMAVMRVGGAARKTGQTDMNATSSRSHLIFTITVTATSKTNAGRGEVTTSRLNLVDLAGSERLSKTNATGERLREARHINKSLSALGNCLNALAEKQQSATESKTAAKHAAHVPFRDCKLTHILSPCLGGDSKTLMFVHAGPAASDASESACTLEFASRVRNVSVTAARKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMT3</accession>
    <name>C1MMT3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56647</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057458.1">
        <property type="nucleotide sequence ID" value="XM_003057412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMT3"/>
    <dbReference type="GeneID" id="9682425"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56647"/>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317">
        <property type="entry name" value="BLR8090 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317:SF1">
        <property type="entry name" value="ZINC-RIBBON DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="2">
        <location>
            <begin position="65"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="2">
        <location>
            <begin position="143"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="207" mass="22979" checksum="2E467BB0F9606F36" modified="2009-05-26" version="1">MRRTRRRSGSAATSSASTSGGRRWATARGAPNPPGCPKCANRIPLSKTNNFLVWCEKNGELGKKLSREYVDKDKPPTAVTKGSDYKAKWKCLKCKHVWRAKVNHRTNSVKPKGCPQCANNAPASKTNNFLAWCEKNGELGKKLSREYVDKDKPATAVTKASNYKAKWKCGTCSCEWRATVKDRTRSVKPTGCPGCYGLRPGKRQRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMU2</accession>
    <name>C1MMU2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_15406</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056989.1">
        <property type="nucleotide sequence ID" value="XM_003056943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMU2"/>
    <dbReference type="STRING" id="564608.C1MMU2"/>
    <dbReference type="GeneID" id="9682903"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15406"/>
    <dbReference type="eggNOG" id="KOG1526">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HGTVQRH"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006739">
        <property type="term" value="P:NADP+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004790">
        <property type="entry name" value="Isocitrate_DH_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822:SF21">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822">
        <property type="entry name" value="NADP-SPECIFIC ISOCITRATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="9">
        <location>
            <begin position="2"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="393" mass="43410" checksum="F9A6C60DD979A863" modified="2009-05-26" version="1">MVYVAGEEMTRYTMQLILDKWVSPHVDTSRWEFFDLRAKNRDDTEDQVLRDVITAGARLKAIFKEPTITPTADQVKRLGLKKAWGSPNGAMRRGWNGITISRDTIHIDGVELGYKKPVFFERHAVGGEYSAGYKIVGKGQLKTTFVPEGGGDAIVVDDRAVVDDLNAVVTYHNPLDNVNHLARIFFGRCLDAGIVPYVVTKKTVFKWQEPFWETMKRVFDDEFKEKFRAKKIIGDNAELVHLLSDAATMKLVVWTDGGFGMAAHNYDGDVLTDELAQVHMSPGFITSNLVGVDADGTLIKEFEASHGTVTDMDEARLRGEETSLNPLGMVEGLIGAMNHAADVHGGADAVHPYTAKLRAVIHKLFREGRGTRDLCGAGGLTTEQFIDAVAAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN12</accession>
    <name>C1MN12_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56739</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057501.1">
        <property type="nucleotide sequence ID" value="XM_003057455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN12"/>
    <dbReference type="GeneID" id="9682461"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56739"/>
    <dbReference type="OrthoDB" id="10661990at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="764"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="165"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="565"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="655"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="670"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="728"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="765"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="784" mass="83372" checksum="4351CFE6F37850D8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNX5</accession>
    <name>C1MNX5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_25533</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057188.1">
        <property type="nucleotide sequence ID" value="XM_003057142.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNX5"/>
    <dbReference type="STRING" id="564608.C1MNX5"/>
    <dbReference type="GeneID" id="9682627"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25533"/>
    <dbReference type="eggNOG" id="KOG3151">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HIMDGYF"/>
    <dbReference type="OrthoDB" id="8775810at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.990:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006746">
        <property type="entry name" value="26S_Psome_Rpn12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12387">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12387:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSN8/PSMD8/EIF3K" evidence="3">
        <location>
            <begin position="113"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="277" mass="30359" checksum="5227FC0DACB65EFC" modified="2009-05-26" version="1" fragment="single">MSAEGLPMTGYLPTAQQNFAAMKKAYAAGDVAKTSSLLATLKVALTTFPALPPLCAHTSTVEKELLLARDVLEYAALFAVSQDDHDAVERACTQLKTYYADKYCVTRMKRSERQNLITGLNLTRLLVQNRIAEFHTELELIPAETQADPRVKLPIELEQRLMEGSYDKILKQSKAALPSPEFGNFMKSLTATVKDEIAACMEKAYATLSAAAAAKMLGIGSGVEMNAFGESRGWVRSPDGLRFVFQKEKAPPSAKDIPSGTLIAQTMMYAKELERIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPX0</accession>
    <name>C1MPX0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Photosystem I reaction center subunit III</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">PSI-F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PSAF</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_26202</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria). This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast thylakoid lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PsaF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057659.1">
        <property type="nucleotide sequence ID" value="XM_003057613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPX0"/>
    <dbReference type="STRING" id="564608.C1MPX0"/>
    <dbReference type="GeneID" id="9683461"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26202"/>
    <dbReference type="eggNOG" id="ENOG502QTZ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CIGWAGR"/>
    <dbReference type="OrthoDB" id="1920411at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
        <property type="term" value="C:photosystem I reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.110:FF:000001">
        <property type="entry name" value="Photosystem I reaction center subunit III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.110">
        <property type="entry name" value="Photosystem I PsaF, reaction centre subunit III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003666">
        <property type="entry name" value="PSI_PsaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036577">
        <property type="entry name" value="PSI_PsaF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34939">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT III, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34939:SF1">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT III, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02507">
        <property type="entry name" value="PSI_PsaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81536">
        <property type="entry name" value="Subunit III of photosystem I reaction centre, PsaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="240" mass="24903" checksum="A78573A1287A7373" modified="2009-05-26" version="1">MAAMMSLNAVAPAKLSSKMSTGITAKAPVAAKAPVSTVVKASAKDAAAKSAAVAAAVAVAVAAPMVVAPEEAFARDVAPYAGLTPCKKNAAFKKREKQEIKALEKRLKKYEEGSAPALALKATQDKTSARFKAYGEAGLLCGADGLPHLIVDGNLEHLGEFAIPGLGFLYVAGWIGYAGRSYVMLNKEQSKKPTEGEIIIDVPMALGLMMAAGAWPVKAFFELKNGTLTAPASEITVSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQQ3</accession>
    <name>C1MQQ3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="13">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_15822</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058165.1">
        <property type="nucleotide sequence ID" value="XM_003058119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQQ3"/>
    <dbReference type="STRING" id="564608.C1MQQ3"/>
    <dbReference type="GeneID" id="9683238"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15822"/>
    <dbReference type="eggNOG" id="KOG2431">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AAFKHSW"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF55">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 13 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912080" description="alpha-1,2-Mannosidase" evidence="15">
        <location>
            <begin position="24"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="36"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="36"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="472"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="595"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="429"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH58116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="631" mass="67521" checksum="1B880A5BE9CB99E1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQT1</accession>
    <name>C1MQT1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_26419</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057811.1">
        <property type="nucleotide sequence ID" value="XM_003057765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQT1"/>
    <dbReference type="STRING" id="564608.C1MQT1"/>
    <dbReference type="GeneID" id="9683620"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26419"/>
    <dbReference type="eggNOG" id="KOG2562">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TEWDRYC"/>
    <dbReference type="OrthoDB" id="5586at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21504">
        <property type="entry name" value="PPP2R3A_B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.220:FF:000003">
        <property type="entry name" value="Phosphoprotein phosphatase 2A regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000025">
        <property type="entry name" value="serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041534">
        <property type="entry name" value="EF-hand_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095:SF0">
        <property type="entry name" value="MIP22305P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095">
        <property type="entry name" value="PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17958">
        <property type="entry name" value="EF-hand_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PP2A regulatory subunit B'' EF-hand" evidence="5">
        <location>
            <begin position="176"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="288"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="10"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="506" mass="57737" checksum="2035987BE5744E99" modified="2009-05-26" version="1">MPSTPTIGGSPLSPSSTHALLSATALSTPPLSPSKAATPPASPMSPGKRRAAAAAASAAAKRRAPDAIPRFYFGPNKEAYGDEQSATKLAEAALIFDGEALDADAFRRVTREVCELPSYFAPLVMHRIHGTEPMEVDEDDPTKAANAPTAPAREPAPVTWAQFTEYWNSTLRKHADSNARVFEVLRGPKPNGPNGPRAYLEHADFRSILRCILDTHPGLEFLKDSPEFQDRYLETVTYRIFYACNTAWNGKMTLRELRRSNLVEAMNHVDEEEDINKVLKYFSYEHFYVIYCKFWELDTDHDFLIDKEDLLRYGNHALTYRAVDRVFAQAPRRFVSGVKNKMGYEDFVWFILSEEDKSTPLSLEYWFRCVDLDGDSELSPSECAFFYEEQLQRMECLSQEPVLFEDILCQMCDMLKPAENGKITLRDLRRCKLAGNFFNVLFNLNKFIAFETRDPVLIRQEREEPHLTEWDRFARQEYIRLSMEEEEGMAEGGEMWDDGDVDASPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR21</accession>
    <name>C1MR21_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_8212</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058230.1">
        <property type="nucleotide sequence ID" value="XM_003058184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR21"/>
    <dbReference type="STRING" id="564608.C1MR21"/>
    <dbReference type="GeneID" id="9683668"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8212"/>
    <dbReference type="eggNOG" id="ENOG502S7BX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LECVVGY"/>
    <dbReference type="OrthoDB" id="495795at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34276">
        <property type="entry name" value="MINI-RIBONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34276:SF1">
        <property type="entry name" value="MINI-RIBONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="116" mass="13178" checksum="C4401A1ABFF47BFD" modified="2009-05-26" version="1" fragment="single">AFLGDAVWELYVRRLFFAPPTRPRTYDLKCKRAVRAEAQDVVLRKLVDRGFFTDEEMKVVKWGRNASYGNVPTRLRGKNGKGGFATYRNASALECVVGYLYMTDSARLETMMATLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR34</accession>
    <name>C1MR34_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47132</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057860.1">
        <property type="nucleotide sequence ID" value="XM_003057814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR34"/>
    <dbReference type="GeneID" id="9683674"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47132"/>
    <dbReference type="OMA" id="CDYSNMD"/>
    <dbReference type="OrthoDB" id="9989223at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47485">
        <property type="entry name" value="THYLAKOID LUMENAL 17.4 KDA PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47485:SF1">
        <property type="entry name" value="THYLAKOID LUMENAL 17.4 KDA PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="23"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="268" mass="27871" checksum="0F97DEBC435FB8F7" modified="2009-05-26" version="1">MTIAALGRQLASPRVVARRRQPAKTTTTTTTKTKTKTRSFAATTTRASSSSSSSSSDAAARAPFATTCASAALATAAALTLALSTPDASIAGTPKGQGVASGDAYGRTDVDRCSREALKKAANTRAAFSDFATQQNEELYVNVEGCDYSNMDLSDEVLSGVKARGANFENSIFGAESSRADFSDANLRGAVIRSVNLYNTIFAGADLEGADLSGSLAPGAFFGRDEQTGKKANLKDVNFEDTLLSSSDVRTICANSSLTFESKMSLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRB1</accession>
    <name>C1MRB1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal protein L37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_33223</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic ribosomal protein eL37 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058272.1">
        <property type="nucleotide sequence ID" value="XM_003058226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRB1"/>
    <dbReference type="STRING" id="564608.C1MRB1"/>
    <dbReference type="GeneID" id="9683339"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33223"/>
    <dbReference type="eggNOG" id="KOG3475">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AREHHIF"/>
    <dbReference type="OrthoDB" id="528079at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000001">
        <property type="entry name" value="Ribosomal protein L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00547">
        <property type="entry name" value="Ribosomal_eL37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001569">
        <property type="entry name" value="Ribosomal_eL37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018267">
        <property type="entry name" value="Ribosomal_eL37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01907">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01077">
        <property type="entry name" value="RIBOSOMAL_L37E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="100" mass="11345" checksum="85E3F7DE608E4666" modified="2009-05-26" version="1">MGKIGKGTGSFGKRHNKSHTMCRRCGRRSYHIQKATCGACGYPSARKRNYNWSTKAIGRRTTGTGRMRYLKTLPRRFKNGFREGAREHHIFSSFTGGFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRE3</accession>
    <name>C1MRE3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ubiquinone/menaquinone biosynthesis methyltransferase, bacterial-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">UBIE</name>
        <name evidence="1" type="ORF">MICPUCDRAFT_16450</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058293.1">
        <property type="nucleotide sequence ID" value="XM_003058247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRE3"/>
    <dbReference type="STRING" id="564608.C1MRE3"/>
    <dbReference type="GeneID" id="9683350"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16450"/>
    <dbReference type="eggNOG" id="KOG1540">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DRVAPTY"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="256" mass="28741" checksum="DD0D109AF3C602A6" modified="2009-05-26" version="1">MAPSPRASTSAFDAHAPEDGYRLQGDEKLAFVTDMFDRVAPTYDLLNWFISLGQTTLWRLMALSFLRPYLRARAKVLDVGCGTGWVSWYFAWRYKDMKLDVEGVDCSPVMLDRARVVVPGGRFTRGDVCALTHDDDAFDVVTTVYTLRNFPNLERGLREMYRVCAPGGVVIILDAFPAKNFAMRCVLYAWLELVMPLVAMLFTRDAKAYRYLSASIRATAAVEEVTEMLYECGAVRVEIAKYTFGAAARLVAHKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSP2</accession>
    <name>C1MSP2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_57766</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058361.1">
        <property type="nucleotide sequence ID" value="XM_003058315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSP2"/>
    <dbReference type="STRING" id="564608.C1MSP2"/>
    <dbReference type="GeneID" id="9684150"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57766"/>
    <dbReference type="eggNOG" id="KOG2253">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DGCVNKK"/>
    <dbReference type="OrthoDB" id="6275295at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12446">
        <property type="entry name" value="RRM_RBM25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052768">
        <property type="entry name" value="RBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034268">
        <property type="entry name" value="RBM25_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806">
        <property type="entry name" value="RBM25 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806:SF4">
        <property type="entry name" value="RNA-BINDING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="92"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="PWI" evidence="4">
        <location>
            <begin position="628"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="523"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="460"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="720" mass="75664" checksum="3D59D393A38B70AD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSY8</accession>
    <name>C1MSY8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57874</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058403.1">
        <property type="nucleotide sequence ID" value="XM_003058357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSY8"/>
    <dbReference type="GeneID" id="9684204"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57874"/>
    <dbReference type="OMA" id="LWVLREC"/>
    <dbReference type="OrthoDB" id="415230at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="253" mass="27051" checksum="968D32995C542941" modified="2009-05-26" version="1">MPPKKDKAKLKKGSSSSGSAEGPLVQLRPSEILYTYSKVLPYFSGCGRTLRHTLEEIARGAMRPSDLPAIAVISAEVPSATGTSDARDTRACGDKGPSHDGWSSDEDGGKRGGGKRGGGKRRGGGDRRDERKPSDEKVVKYFSTNNRRLWVLRECEARGLLGPEGTIGVRLQRPDVSKRMVEKGTRSFRLERCTDKVTLVKASEPNKTEDGDDGDGGDDDDDAPTDDAKDDDNGGGDGAAVDDVNEGVAAMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT85</accession>
    <name>C1MT85_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47275</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the chalcone isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058444.1">
        <property type="nucleotide sequence ID" value="XM_003058398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT85"/>
    <dbReference type="STRING" id="564608.C1MT85"/>
    <dbReference type="GeneID" id="9683882"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47275"/>
    <dbReference type="eggNOG" id="ENOG502S81H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YACGLYV"/>
    <dbReference type="OrthoDB" id="18193at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.890.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016089">
        <property type="entry name" value="Chalcone_isomerase_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698:SF2">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16035">
        <property type="entry name" value="Chalcone_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="Chalcone isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chalcone isomerase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="171" mass="18342" checksum="195AA7720A344B00" modified="2009-05-26" version="1">MGVRVKRIAGIGVKVYACGLYVDPEDARAALGDRFVGRDVADVGKDQSLFDGVLRSDDVDKTVRLAFARNIDSAKIRDALSERLRPALGRDSESLKTFETYFDGVTFEKGQALTFSATGGKLETTMKGKSVGVIHDARLCAALFDAYLGRDPVVPSAKRSLGEALAARVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTT5</accession>
    <name>C1MTT5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_58544</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YSL (TC 2.A.67.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059375.1">
        <property type="nucleotide sequence ID" value="XM_003059329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTT5"/>
    <dbReference type="STRING" id="564608.C1MTT5"/>
    <dbReference type="GeneID" id="9684815"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58544"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF0">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="64"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="218" mass="22865" checksum="E437FC66E1A83D26" modified="2009-05-26" version="1">MKPAHDGDVDPLSLRAVLAGFVVGFVVSAMNVSFGLKAGWAQGGRRVATDRSLAADENASIVATRRRISSRRPSFPPPSDAPSPPPTPPSLPLRAPSSSSPPLVRRSILAAAVSIGLFSALKPKVPFTQAEANICQTVASAAGSMTMAAGLIGPIPALQMLGHKYDGLTIMAWGASVAYLGVFFAVPMRRHFLVDHPLKARSIHWSPYDPVGVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU03</accession>
    <name>C1MU03_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58619</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059410.1">
        <property type="nucleotide sequence ID" value="XM_003059364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU03"/>
    <dbReference type="STRING" id="564608.C1MU03"/>
    <dbReference type="GeneID" id="9684571"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58619"/>
    <dbReference type="eggNOG" id="ENOG502R8D8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF1">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="141" mass="14971" checksum="9BB7942EB357A78B" modified="2009-05-26" version="1">MDAPNRELLLILRTGAKTAGHPRWTHGGFTSLLMDEMAGQAYAEFVQPTRGIGMTANLTVNFASPLPTDSDLLVVAGVERTEGRKVWLRVEVRDGPRRACEVDGRAARGANVEDDDAGGGGESEGTLFASGSALFIVLAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU62</accession>
    <name>C1MU62_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_40141</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RUS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059438.1">
        <property type="nucleotide sequence ID" value="XM_003059392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU62"/>
    <dbReference type="GeneID" id="9684509"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40141"/>
    <dbReference type="eggNOG" id="KOG4249">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PKRWWAV"/>
    <dbReference type="OrthoDB" id="364779at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006968">
        <property type="entry name" value="RUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054549">
        <property type="entry name" value="UVB_sens_RUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770:SF27">
        <property type="entry name" value="PROTEIN ROOT UVB SENSITIVE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770">
        <property type="entry name" value="RUS1 FAMILY PROTEIN C16ORF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04884">
        <property type="entry name" value="UVB_sens_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein root UVB sensitive/RUS" evidence="3">
        <location>
            <begin position="145"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="453"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="568" mass="60920" checksum="94080F1DEEBF734E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUX1</accession>
    <name>C1MUX1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40303</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059264.1">
        <property type="nucleotide sequence ID" value="XM_003059218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUX1"/>
    <dbReference type="GeneID" id="9685016"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40303"/>
    <dbReference type="eggNOG" id="ENOG502SB5T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NIKCAAS"/>
    <dbReference type="OrthoDB" id="2017163at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="291" mass="31429" checksum="77354E55188B20F8" modified="2009-05-26" version="1">MAEMMAKLQAAEAEAEKLRSELRAQPEPPTATVDELARQKPAKPESRVDGTGGRETLFGAPSGDSWLSDGMEFLVRTQPSEAGELPEMDEEAKNEVNRRLAIGLFGTAVFAALSQISDEAPTPSKPLFFYLVPLVKIRELLRQAESLAEDGYWEELSTVCNQISRGNDPKGNLFAAAAYLDASQEVKAKAIAFDFLELLEKIDYNKYFENMGAVSGAKAAEYSKFSKRAAAASASKLDEFLALMDREQLDAARSQVLPPPPEPEPEPEPAAVEAASGGEGGGFSGSYGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV45</accession>
    <name>C1MV45_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59049</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059605.1">
        <property type="nucleotide sequence ID" value="XM_003059559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV45"/>
    <dbReference type="GeneID" id="9685045"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59049"/>
    <dbReference type="OMA" id="LPREQCF"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039438">
        <property type="entry name" value="At2g23090-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12907">
        <property type="entry name" value="zf-met2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="At2g23090-like zinc-binding" evidence="2">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="96" mass="10469" checksum="50E42E01E43A325D" modified="2009-05-26" version="1">MNKLQIQLKKKEKERKDAAGKKSASTKEAKASVEAANRGHVCRVCRWAAMVTAKSPQLMQHVDAKHAKLRPEECFPEIIEMLAAEAAGGGGKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV77</accession>
    <name>C1MV77_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_59084</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGU family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059619.1">
        <property type="nucleotide sequence ID" value="XM_003059573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV77"/>
    <dbReference type="STRING" id="564608.C1MV77"/>
    <dbReference type="GeneID" id="9684767"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59084"/>
    <dbReference type="eggNOG" id="KOG2552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ALWHLWI"/>
    <dbReference type="OrthoDB" id="498246at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009600">
        <property type="entry name" value="PIG-U"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS CLASS U PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06728">
        <property type="entry name" value="PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912096" evidence="11">
        <location>
            <begin position="24"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="158"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH56751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="489" mass="52264" checksum="FEEF649B90BA0E49" modified="2009-05-26" version="1">MHLSPRVAAAIALASVLLRFVLAARGWGEILHARPELSSAVDAATRLREGDALRRLGQSPYAGSALHAPPLLLAALAPRIASAPTIGTRAVAPFVVFDVLAAFALFFASRRIEARRIVWSRAGSAGGPGASAAAKREASRRVASTPWTVAALSLANPLAIASCVACSCAGLRTAALAFLIFGASCGNPHVAGFGLATSAYLGGIAPLAMLFAPTASAIAKGGAEGHRPGVDGGMRGREIARRSAAEVSGHSPATATAKLFAWTTTWLFALTWLSTDILRGHASFDDWFRACYVYLLVPDDLAPNLGAHWYFFSELFDHFVGFYRFVFAFFPAFLATPLTIRFIDSRPTFAIFGVTCLGCIMHPYPTLGDAARYLSLLPLFSEELAAFHPGAAFAVVAGFFYVILLSPIFWRLWIVDRVANANFFYAVTLTYFAVQSGLFIECARVVLRHDFSTKVALGLDKESLLRAAAAAEGGSDDDDDDDHHHDHAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVD5</accession>
    <name>C1MVD5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_7217</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059732.1">
        <property type="nucleotide sequence ID" value="XM_003059686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVD5"/>
    <dbReference type="STRING" id="564608.C1MVD5"/>
    <dbReference type="GeneID" id="9685458"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7217"/>
    <dbReference type="eggNOG" id="KOG3114">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RCSILSW"/>
    <dbReference type="OrthoDB" id="10256463at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039765">
        <property type="entry name" value="Yip5/YIPF1/YIPF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="7">
        <location>
            <begin position="39"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH55684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="175" mass="19382" checksum="097C6E684465A588" modified="2009-05-26" version="1" fragment="single">KKTGWIFSAAYYQQWFDVDTDDVLSRTFEATAKCYAGSFARACDGNPDLYGPFWICATLVFLHAMGGNYAQYMSSKGKSDGEEWSFDIEKISVSSAMFFGYCSVAPVLLYLVLRCFAGVPTTSLSFVQLVSTYGYALTVYVPVSLLCVVPSEAFRWMSFIAGMAVSASFLFTNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW64</accession>
    <name>C1MW64_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferroxidase</fullName>
            <ecNumber evidence="3">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_9181</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the frataxin family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="3"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059868.1">
        <property type="nucleotide sequence ID" value="XM_003059822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW64"/>
    <dbReference type="STRING" id="564608.C1MW64"/>
    <dbReference type="GeneID" id="9685601"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9181"/>
    <dbReference type="eggNOG" id="KOG3413">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SECEVEY"/>
    <dbReference type="OrthoDB" id="1897642at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034986">
        <property type="term" value="F:iron chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="entry name" value="Frataxin/CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017789">
        <property type="entry name" value="Frataxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03421">
        <property type="entry name" value="FeS_CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03422">
        <property type="entry name" value="mito_frataxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="FRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821:SF2">
        <property type="entry name" value="FRATAXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00904">
        <property type="entry name" value="FRATAXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="Frataxin/Nqo15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0409">Iron storage</keyword>
    <keyword evidence="6" id="KW-0410">Iron transport</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH55820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="115" mass="12557" checksum="776B8FF78A330668" modified="2009-05-26" version="1" fragment="single">DDLTFQAAADAALRRVETVVDRWGEDRATLPDFDLNAESGVVTIALGGGHGTYVLNKQAPNRQIWMSSPVSGPTRYDYDDERRAWIYARDGHALHERLASELTAIGGGEVDLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWA7</accession>
    <name>C1MWA7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_34378</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060182.1">
        <property type="nucleotide sequence ID" value="XM_003060136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWA7"/>
    <dbReference type="STRING" id="564608.C1MWA7"/>
    <dbReference type="GeneID" id="9685331"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34378"/>
    <dbReference type="eggNOG" id="KOG2345">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PFEMTIN"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052239">
        <property type="entry name" value="Ser/Thr-specific_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998:SF2">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="48"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="363"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH56134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="377" mass="41151" checksum="314990CE094FB79C" modified="2009-05-26" version="1">MSAYFARMLEQYGCNVDGIWRAVVDAGKQVGLTLPPLTEEVVVEDKTFAIVKKLGEGGFSYVHLAREIPDLASEDYALKRILIHEEEHQGAIQNEIDVMRALDHPNILPLLYAEIEPHRSPPPGARVFVRKRASLVFPAYLDGTMFDRATTRPEADAFTSTQLMSIAAQLCDALECMHTLSPPLGPIAHRDVKLDNVLLESSPETEGGLKAVLMDFGSAKPAKVTVTDRSQALLIQEKAAGECTASYRAPELWDTPSECVIDERVDVWSLGCLLFAATAAGKTPFEYATDAAGGSLALAVMSGKYAWSEAARKAYPREVMAVAECCLEKDWRARPRARDVREKAREALATTRRKFLGGGGEGAGDDDEPAVLVTEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWE0</accession>
    <name>C1MWE0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59731</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060198.1">
        <property type="nucleotide sequence ID" value="XM_003060152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWE0"/>
    <dbReference type="GeneID" id="9685636"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59731"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="291" mass="29725" checksum="FE01B9F748A9C1E0" modified="2009-05-26" version="1">MPAVCTARALTPRAAAGPCRHRPANGRLLPLRKPLPASRVAAFDLRRPASGSSAASRARGGRATSTSTTTTRATPPDADGPEANAYDDDDADVAADAADADDNADDALAPRAGTTREGSEDDDPFDYLSSADPPNDPAKSKSSAASPSPTPAAEPAPSLAPPTPSPAPAPEAAEAAARDAALPPTPPPTPNPPPSTRPPPPPYDGAQFDVRGDAVFGDTYANYPGYEGVYVDNTNEENDRRGIVAPSPEQLLAAAAAAPAPALSPDEKMAAAALELRRVLYTSSHTTALAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWG1</accession>
    <name>C1MWG1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_40727</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059918.1">
        <property type="nucleotide sequence ID" value="XM_003059872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWG1"/>
    <dbReference type="GeneID" id="9685648"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40727"/>
    <dbReference type="OMA" id="ANSWFMQ"/>
    <dbReference type="OrthoDB" id="10634628at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="269"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="376"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="438"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="313"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="399"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="479"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="610" mass="64123" checksum="E486A44EC24F671D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWT5</accession>
    <name>C1MWT5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="9">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_49634</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the SHMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="9"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059685.1">
        <property type="nucleotide sequence ID" value="XM_003059639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWT5"/>
    <dbReference type="STRING" id="564608.C1MWT5"/>
    <dbReference type="GeneID" id="9685121"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49634"/>
    <dbReference type="eggNOG" id="KOG2467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CQFANVQ"/>
    <dbReference type="OrthoDB" id="10265628at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000050">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF28">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="10">
        <location>
            <begin position="53"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH55637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="517" mass="56853" checksum="6ED129FD3ACB9420" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWX2</accession>
    <name>C1MWX2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40483</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059705.1">
        <property type="nucleotide sequence ID" value="XM_003059659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWX2"/>
    <dbReference type="GeneID" id="9685435"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40483"/>
    <dbReference type="OMA" id="GNALAMD"/>
    <dbReference type="OrthoDB" id="1882119at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1033"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1076" mass="114990" checksum="A7E127A9866AEA30" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWZ9</accession>
    <name>C1MWZ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59311</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060008.1">
        <property type="nucleotide sequence ID" value="XM_003059962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWZ9"/>
    <dbReference type="GeneID" id="9685446"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59311"/>
    <dbReference type="OMA" id="IAYICCE"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="621" mass="67550" checksum="C36F13ECBBFE4EB6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXS2</accession>
    <name>C1MXS2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60267</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060741.1">
        <property type="nucleotide sequence ID" value="XM_003060695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXS2"/>
    <dbReference type="GeneID" id="9686178"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60267"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910552" evidence="2">
        <location>
            <begin position="39"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="438" mass="46491" checksum="57FC180496C47BA6" modified="2009-05-26" version="1">MTRARGGAGPRPRPPRPRACFVLLALTTCALLLGGARTRAPERDPAPASSSAPRVRTARALLRSDDDPADLVALDASSSSSSSSSPRVAALGSDAVAVADADADAPASASNASAAALPAALPAALPAAHPLPTNDDGTLRYPNDITGTFKGTWRLIKKLGADGNANGTTGGLPGMRRAKAREGGGGKRRAGKGDDDDDDDDDDGGGGVVVIQLVSRWNNLKTVQWTRADVAFRDGEYITQRDVHMRLDGVYVAPTGMTHLASEPSAGFRGAEATYNASDPADVDAADGGYREALRVAARDFVNEPFSTERAVALAWEGSLSSRPEHVPGSPHLSQMRRKERSRRREEAGVGTYPGRCAFTMKTWVTPGRFKPVSDAFGNGGEFDEEDQPANGVEGVGVDGERARRVKSRRRRRRSSADKVRSIHWSPYHRVRVVNAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY49</accession>
    <name>C1MY49_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_69293</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060809.1">
        <property type="nucleotide sequence ID" value="XM_003060763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY49"/>
    <dbReference type="GeneID" id="9686246"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69293"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="114" mass="12491" checksum="101636FAF7E579AC" modified="2009-05-26" version="1">MVRRARSRWNASPAGGLWIRPSLLWWSSRPRPGPGPGPARRRSRCPRTRRRDGDDGHAAFQWCELRGFDPSATIEDWNDGSTTAAGSRREASDPSGEGGGSSSKRTRGSSTSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYU6</accession>
    <name>C1MYU6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_34805</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061101.1">
        <property type="nucleotide sequence ID" value="XM_003061055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYU6"/>
    <dbReference type="STRING" id="564608.C1MYU6"/>
    <dbReference type="GeneID" id="9686284"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34805"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YCLPYVI"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="PiNMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF11">
        <property type="entry name" value="GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="8">
        <location>
            <begin position="117"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif I" evidence="6">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif II" evidence="6">
        <location>
            <begin position="181"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="6">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="335" mass="36711" checksum="D7F9194BEEC91DD9" modified="2009-05-26" version="1">MRKALFPRGRRASEESSSSTSRPTPTTPRATNVPTSSGFNGLEDLASPFVKKHDALNEGIASFYDESSELWEDIWGEHMHHGYYPNGVARADHRQAQVDMVDNALEWAGVTDVKRALDVGCGIGGGSRHLSRKFGCAATGVTLSPVQAARANEITADAADVDESLVRVQVADALHTPFEDAAFDLVYSMESGEHMPDKEAFVNELARVCAPGGQILIVTWCHRVLDASEKELPPDERSLLDRICEAYYLPPWCSVATYEKHFASAGLVDVRTEDWSREVSPFWRAVIETALTWRGVIGLLKAGPSTIRGGLVMPLMSKGLRDGTIKFNLITARKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYW8</accession>
    <name>C1MYW8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_19691</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060855.1">
        <property type="nucleotide sequence ID" value="XM_003060809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYW8"/>
    <dbReference type="STRING" id="564608.C1MYW8"/>
    <dbReference type="GeneID" id="9686552"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19691"/>
    <dbReference type="eggNOG" id="KOG0450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RFHAVIG"/>
    <dbReference type="OrthoDB" id="413077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF35">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="6">
        <location>
            <begin position="517"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="535"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="755"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="773"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="930" mass="102050" checksum="5589609E6E8927BC" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ51</accession>
    <name>C1MZ51_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60604</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060896.1">
        <property type="nucleotide sequence ID" value="XM_003060850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ51"/>
    <dbReference type="GeneID" id="9686594"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60604"/>
    <dbReference type="OMA" id="TINFHLQ"/>
    <dbReference type="OrthoDB" id="494426at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="56" mass="6451" checksum="D0F9C3E3A93E83BB" modified="2009-05-26" version="1">MTALLTCFKMCDFGNDTRCAGEKRALNDCLTLHATRPKQKQTINFHLQRLARLAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZI8</accession>
    <name>C1MZI8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_63421</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060961.1">
        <property type="nucleotide sequence ID" value="XM_003060915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZI8"/>
    <dbReference type="GeneID" id="9686400"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63421"/>
    <dbReference type="eggNOG" id="ENOG502SCM8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="236"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="447" mass="48560" checksum="B51945D2A81209D1" modified="2009-05-26" version="1">MCTNGVKANDDDGDDSLREALKIAILLGEAGADARLANRFAEPPLIACVLAGGFIPGMTILLEFGADPKQESTGNGNVSAYGMVFGSGPMPMKTARALLSADVYKEGGVVGRDVRVHGLTSASAKALNGKVGTVRRLDPVTGKYEVSLHGEEDRIISIAPWKLKLAEEMFGCVVRLKDLTGRSELNGRRGICGTYLRHRGRYEIAVQATNDAPAEKISVKPCNIERLERLSKIGNCAGCGVAASSDEKKPKGSKKKGERAKESAKDDARVKLRYCGRCYTVVYCGDECVKANWNLHKEECAARCANQARINLQRIKESTPRGMSFSTVNMQTHQIDALNEFGEIVASKNESFTVKVQIPLVPPGMGRTLQNGMGAMVYDEKRRLQFHIPANPPFEKEYQQAVEHVESKGLTAMGSAKGVKAYFPARLIDSGKTILIDFHEALTPPAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0I8</accession>
    <name>C1N0I8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="26">Dynein heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="26" type="primary">DHC4</name>
        <name evidence="26" type="ORF">MICPUCDRAFT_35233</name>
    </gene>
    <organism evidence="27">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26 27">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061397.1">
        <property type="nucleotide sequence ID" value="XM_003061351.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N0I8"/>
    <dbReference type="GeneID" id="9687087"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35233"/>
    <dbReference type="eggNOG" id="KOG3595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HNVAKMV"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000003">
        <property type="entry name" value="Dynein heavy chain 12, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000002">
        <property type="entry name" value="Dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000223">
        <property type="entry name" value="Dynein heavy chain 3, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000063">
        <property type="entry name" value="dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001328">
        <property type="entry name" value="Dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000005">
        <property type="entry name" value="Dynein, axonemal, heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000006">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000362">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF73">
        <property type="entry name" value="DYNEIN AXONEMAL HEAVY CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="10 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0243">Dynein</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain linker" evidence="17">
        <location>
            <begin position="632"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="18">
        <location>
            <begin position="1162"/>
            <end position="1488"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA 5 extension" evidence="22">
        <location>
            <begin position="1665"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein 2 heavy chain 1 cytoplasmic ATPase lid" evidence="25">
        <location>
            <begin position="2000"/>
            <end position="2085"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="20">
        <location>
            <begin position="2159"/>
            <end position="2419"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="19">
        <location>
            <begin position="2433"/>
            <end position="2781"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="21">
        <location>
            <begin position="2810"/>
            <end position="3031"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain region D6 P-loop" evidence="16">
        <location>
            <begin position="3277"/>
            <end position="3389"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="23">
        <location>
            <begin position="3422"/>
            <end position="3559"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="24">
        <location>
            <begin position="3565"/>
            <end position="3867"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="540"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="2666"/>
            <end position="2728"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="2968"/>
            <end position="3006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF17852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF22597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="EEH54027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="3872" mass="437548" checksum="1BEFB43057EA2440" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0Q6</accession>
    <name>C1N0Q6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_7124</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061681.1">
        <property type="nucleotide sequence ID" value="XM_003061635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0Q6"/>
    <dbReference type="STRING" id="564608.C1N0Q6"/>
    <dbReference type="GeneID" id="9686872"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7124"/>
    <dbReference type="eggNOG" id="KOG0324">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RTECSAH"/>
    <dbReference type="OrthoDB" id="412286at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101005">
        <property type="term" value="F:deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF9">
        <property type="entry name" value="OS06G0107000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="4">
        <location>
            <begin position="2"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="18570" checksum="D87C2A5DE57BA030" modified="2009-05-26" version="1" fragment="single">MSLVTLHVYDITNTTYETANNVIQGLNRFTKDALGAGGIFHGAVEVNGDEWSYGFCERGSGVYCCHPRGNTGYTYRESVPLGVTSLSPARVRSVIAVLQAQWPGCEYDLLGKNCNHFCEAFGAMLGVPGPPAWVNRFATQAEATVKTVNYAREQISLIGGEIGSAATAAADWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0X9</accession>
    <name>C1N0X9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_51188</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061473.1">
        <property type="nucleotide sequence ID" value="XM_003061427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0X9"/>
    <dbReference type="GeneID" id="9687152"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51188"/>
    <dbReference type="eggNOG" id="KOG1581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF13">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="459"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="487" mass="50854" checksum="F786C54F74C7D8B7" modified="2009-05-26" version="1">MFARRATRGESPVAGVDDDLGGSPRQIASGGLGGVLADETASSSGPGPSSVRAAPPAATASPDRRTPLNFVICVGGVIASLSAYGVLQERLMTQPYDGENGPETFTHSVFLVLVNRVATVVVAGCGLALTGGSFAAGSRQLLVAYAVVACSNWTTTVCQYEVLKYLSFAASTLTKCAKILPVMAWGRVVLRKRYGSADVAVAVAVTFGCFLFAMDRGVLRTSPTVGGATKKHDDAFAAFDDGNGGKGNRRGGGAREDVVVKAADAHESAKAIAKARRAKTRAAAAASAAAIAASGAASAKDDEMIVTGAVIMLVYLACDGFTSTTQQWLFRRHATPVLSQIFFTTCFACVFSFAWLSSTSQLGEAIGFVTRHPRALQDVFVLAVSACAAQFAINYTIYCFGAVTLASVMTFRQFLAVVLSCFAFGTPLTGAQWFALVLILAPVMKRIDSGAIGRYFAPESDGGGTKREKDVEGGRGASWSAPRAFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1N107</accession>
    <name>C1N107_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ferrochelatase</fullName>
            <ecNumber evidence="9">4.98.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HEMH</name>
        <name evidence="11" type="ORF">MICPUCDRAFT_51216</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>heme b + 2 H(+) = protoporphyrin IX + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.98.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Plastid</location>
            <location evidence="1 9">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ferrochelatase family.</text>
    </comment>
    <dbReference type="EC" id="4.98.1.1" evidence="9"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061489.1">
        <property type="nucleotide sequence ID" value="XM_003061443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N107"/>
    <dbReference type="STRING" id="564608.C1N107"/>
    <dbReference type="GeneID" id="9687164"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51216"/>
    <dbReference type="eggNOG" id="KOG1321">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MGVANEH"/>
    <dbReference type="OrthoDB" id="1323at2759"/>
    <dbReference type="UniPathway" id="UPA00252">
        <property type="reaction ID" value="UER00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1400:FF:000006">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019772">
        <property type="entry name" value="Ferrochelatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108:SF1">
        <property type="entry name" value="FERROCHELATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00534">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="7 9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH54119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="542" mass="58382" checksum="72669219C22AD4AD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N196</accession>
    <name>C1N196_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_20304</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061529.1">
        <property type="nucleotide sequence ID" value="XM_003061483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N196"/>
    <dbReference type="STRING" id="564608.C1N196"/>
    <dbReference type="GeneID" id="9687213"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20304"/>
    <dbReference type="eggNOG" id="KOG1489">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EICICRI"/>
    <dbReference type="OrthoDB" id="347018at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702:SF31">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="5">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="51"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="243" mass="25709" checksum="4D4B0D8E6F9C72B6" modified="2009-05-26" version="1">MDEHKKRILLSKGGRGGKGNRAKPRGELAGTADKGADGGKLTVVLELKSVADLGLVGLPNAGKSTLLRAISDARPNVADYAFTTMSPQLGAVKLDGGLSSVTVADIPGLIKGAHENRGLGHNFLRHVERCAAFLFVVDLSSGMGDRPGMRPWEALKVLRAELDAYLPGLSNRPAIVVGTKTDVARTSKAAEALRRRTDLPVVCVSANASEGIDALLSATEDLLERAKRERDEGEARDVVDVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1E7</accession>
    <name>C1N1E7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51373</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061550.1">
        <property type="nucleotide sequence ID" value="XM_003061504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1E7"/>
    <dbReference type="GeneID" id="9687243"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51373"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="201" mass="19816" checksum="8672181C814E3E52" modified="2009-05-26" version="1">MPAKTKGGGSMVRSGVTRGMSTGVNAGGGGAGIGRGGGDPTHRSSSDLGGLAPPSRPVAPAAKSGSKRSDAAAANAATATATATAREKTKRAKTSTAAETRGRPRTLAPAKLGNVLMTAETYCALLLRRGFTPLVSGERCPRVEGIAATATAKAKAATATATAATATAATGGGGAKERDGSEVRSIHWSPYDRVGDVDADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N214</accession>
    <name>C1N214_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_41979</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062212.1">
        <property type="nucleotide sequence ID" value="XM_003062166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N214"/>
    <dbReference type="STRING" id="564608.C1N214"/>
    <dbReference type="GeneID" id="9687451"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41979"/>
    <dbReference type="eggNOG" id="KOG0715">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KWHLERW"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF58">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="59"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="264" mass="28161" checksum="7461CF44FF96AA1B" modified="2009-05-26" version="1">MTTTTTTIARAPTSVARRRRRHRTATRTSAASSSSSSSSSSSGPGRVPRTPTGARLPLSPYRVLGVAPDATSPEIKLAYRKLVRTTHPDVCDDADAAATFRRVNGAYEIVGADAVRRARFDRGDDWVAMDDGWLPEQRGMAFSPPTGLATSDDEYDDEYDDDGGPWEGGAYYASAYRRRRSDAGAGARGATAATDGGVELADEDRRARGLRRLRRMWATAAWTKWCEAWLAALPVGVPAAVAYFVLVGSIGAGRLGGGGPLIGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N273</accession>
    <name>C1N273_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51872</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062041.1">
        <property type="nucleotide sequence ID" value="XM_003061995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N273"/>
    <dbReference type="GeneID" id="9687680"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51872"/>
    <dbReference type="OMA" id="NWKATHI"/>
    <dbReference type="OrthoDB" id="567830at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="9"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="212" mass="23962" checksum="F0B911D3E7EBE9FF" modified="2009-05-26" version="1">MPSTLTHERARHARLRQAAERKLARFERQRAVRETSRELERLKDECAKQIAQIDDDRAHSLRPSWQLPPGFKCVHFAGQGEFYCVVACKGDAFVSVVDGETSFRLGSTLLTKRGALGWAPVDCCFLAYETPMKALEAPFPKTAKALTLPRVLLKVTTTGNAYEEHKRHGGVTRWTGKVALSRLTVTRVMTDAFRPDLRDPTFFRIRKSFGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2I2</accession>
    <name>C1N2I2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vesicle-fusing ATPase</fullName>
            <ecNumber evidence="4">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_1003</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="4"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061876.1">
        <property type="nucleotide sequence ID" value="XM_003061830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2I2"/>
    <dbReference type="STRING" id="564608.C1N2I2"/>
    <dbReference type="GeneID" id="9687316"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_1003"/>
    <dbReference type="eggNOG" id="KOG0741">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DGMHALN"/>
    <dbReference type="OrthoDB" id="9982946at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000154">
        <property type="entry name" value="Vesicle-fusing ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000166">
        <property type="entry name" value="vesicle-fusing ATPase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000127">
        <property type="entry name" value="Vesicular-fusion protein SEC18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039812">
        <property type="entry name" value="Vesicle-fus_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078:SF3">
        <property type="entry name" value="VESICLE-FUSING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078">
        <property type="entry name" value="VESICULAR-FUSION PROTEIN NSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="42"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="361"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="523" mass="54734" checksum="53561D63E8FF9AC8" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2S3</accession>
    <name>C1N2S3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_69910</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061926.1">
        <property type="nucleotide sequence ID" value="XM_003061880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2S3"/>
    <dbReference type="STRING" id="564608.C1N2S3"/>
    <dbReference type="GeneID" id="9687574"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69910"/>
    <dbReference type="eggNOG" id="KOG0245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62798at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115">
        <property type="entry name" value="KINESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 2" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="5">
        <location>
            <begin position="3"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1006"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="944"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1016"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="105"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1034" mass="114692" checksum="CCCF661A8752E8AC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2T9</accession>
    <name>C1N2T9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_48393</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC6 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062143.1">
        <property type="nucleotide sequence ID" value="XM_003062097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2T9"/>
    <dbReference type="STRING" id="564608.C1N2T9"/>
    <dbReference type="GeneID" id="9687374"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48393"/>
    <dbReference type="eggNOG" id="KOG2286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MNIGPKT"/>
    <dbReference type="OrthoDB" id="190098at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051601">
        <property type="term" value="P:exocyst localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.70">
        <property type="entry name" value="Exocyst complex component Sec6, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010326">
        <property type="entry name" value="EXOC3/Sec6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042532">
        <property type="entry name" value="EXOC3/Sec6_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06046">
        <property type="entry name" value="Sec6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="289"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="444"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="973" mass="103835" checksum="D3ABD75CAB1EF06F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3E2</accession>
    <name>C1N3E2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Voltage-gated ion channel superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_68624</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062363.1">
        <property type="nucleotide sequence ID" value="XM_003062317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3E2"/>
    <dbReference type="GeneID" id="9687803"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68624"/>
    <dbReference type="eggNOG" id="KOG0501">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IFRHREN"/>
    <dbReference type="OrthoDB" id="426293at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003938">
        <property type="entry name" value="K_chnl_volt-dep_EAG/ELK/ERG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050818">
        <property type="entry name" value="KCNH_animal-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217:SF435">
        <property type="entry name" value="POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN EAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217">
        <property type="entry name" value="VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01463">
        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="7">
        <location>
            <begin position="257"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="654" mass="73630" checksum="D3335C8F106AC517" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3X2</accession>
    <name>C1N3X2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_52329</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNAI7 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062689.1">
        <property type="nucleotide sequence ID" value="XM_003062643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3X2"/>
    <dbReference type="STRING" id="564608.C1N3X2"/>
    <dbReference type="GeneID" id="9687889"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52329"/>
    <dbReference type="eggNOG" id="ENOG502R6GJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FTRCEKT"/>
    <dbReference type="OrthoDB" id="297923at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031826">
        <property type="entry name" value="IC97/Casc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023247">
        <property type="entry name" value="IC97/Dnai7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20929:SF11">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20929">
        <property type="entry name" value="LUNG ADENOMA SUSCEPTIBILITY 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15927">
        <property type="entry name" value="Casc1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02043">
        <property type="entry name" value="CANCERSCCP1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IC97/Casc1 N-terminal" evidence="3">
        <location>
            <begin position="48"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="673" mass="74011" checksum="BBFB0B515969BEC8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3X4</accession>
    <name>C1N3X4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_42283</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062690.1">
        <property type="nucleotide sequence ID" value="XM_003062644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3X4"/>
    <dbReference type="GeneID" id="9687890"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42283"/>
    <dbReference type="OrthoDB" id="29221at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="5">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="112" mass="11764" checksum="8A4E9CC6D8051698" modified="2009-05-26" version="1">MENAAKARMGAVPSDLAGGLSGAGAGVSGNKQIGRFFDNQGRFINPAGGFNPSGAPRRIPKEHGQWGDWECDACGGHNRKNRQSCFTCFVPKPPDAKAAVYTSSVGGRKLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N442</accession>
    <name>C1N442_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52402</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062728.1">
        <property type="nucleotide sequence ID" value="XM_003062682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N442"/>
    <dbReference type="GeneID" id="9688168"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52402"/>
    <dbReference type="OrthoDB" id="2124888at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="495" mass="54666" checksum="68CE25AE4098990D" modified="2009-05-26" version="1">MSPPPPAPSEAWVLRSSPSEWDAHAREATAARVHGLCVLDVTHRNIFSYAQGSMDLIRCVHYRVVPIRPRSRGERRSLRTLPGVSLRPSLAFNPRPRRLSTPSDAFELHPAIALYGTTLRKDLDAVLPPAMVKDATRVCDAARLDDAFEVRRNVVNLKKVLLHSWHRAEPLEKELRRLSTFYRCARAHHPSQIHPSGPPPFRRPNPSRTRRRDASFETGFANVHRYRDVCVAHQRLKGATHAVFDGRMMMKQIACVARHPSVERCKKLRGLPGTLTTSSWLANARRFLGDEGVDGFAEFAGGRGKGKGDGGGAAEARAEEEEEDEEEEAPDADADANVYDDDANAVRAQLASFTSLAASLLPGWPAHALAYLERALVARGGAKALSIRRVLYTGSHTTGSAWWTPILKDFARRLSPPRHLRLLQGAAPATRELSHWLDEILTRPRARLFVAGDASSGRATDFVPAGFEIGNAIASYARVVRRVLYAGPRTTASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4E1</accession>
    <name>C1N4E1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_52522</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062774.1">
        <property type="nucleotide sequence ID" value="XM_003062728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4E1"/>
    <dbReference type="STRING" id="564608.C1N4E1"/>
    <dbReference type="GeneID" id="9688214"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52522"/>
    <dbReference type="eggNOG" id="KOG4682">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6359943at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47369">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47369:SF1">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="3">
        <location>
            <begin position="79"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="396"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="453"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="495" mass="51627" checksum="E4395C66F4C7965F" modified="2009-05-26" version="1">MSDPGAQSASHDADVAKDDADGNLDALLSGAYASPRRATSAATSSSSSSLTTRRAALADASVGLAAHVQSLGWEEREFSDVVVSALGKDYPLHRLVLSRSPYFAALMRGPWLDASSPTLTLRFDDVSDLVDVDAVETTLGFLYDKPPTLTTDAAPRVLAAGSFLDLRDLCDICADFIVADVDERTFLRYQNLCEQSAFGMGDPGERGAFYLISHWSPYDPVGVVNAELRGTLHHLSPTTLLKLLRSNDLWVANERARFELVADVTSRLLEESCDGDGDGDGGPDPAAVALRAEALSACVNYQHLPFADLLAIRAELELEDGDFKAACLGSMVAALGEAALRGEAGVGAADAVNAVSAAADAAATSPTRAVVDGLWAQTLLKAHVAAAQGRDGSERGAGASDADAPSRARAPPSRVDESLSRIEIEDGGGGARGESDEDDEDDEDDDDDDDARAGVSNRAAGAAGSSASPMKKRADGGAGTRCVLYTGPHTTALSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4G1</accession>
    <name>C1N4G1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52544</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062783.1">
        <property type="nucleotide sequence ID" value="XM_003062737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4G1"/>
    <dbReference type="GeneID" id="9688434"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52544"/>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="91"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="157" mass="18721" checksum="B4989A1FF7186CFB" modified="2009-05-26" version="1">MENGERGKTLLREFRDPEKLPTELTFRTNYRAKWKCLKCKQAWRARMDNRTRSVRPSGCPKCANKTPRKPMSNSNNFLTWCNANGDRGKKLLREYVDPDREPTQVTKASRYKALWKCETCEHEWRAWMYSRTTTSVRPSDCPQCNLRGRKKKRQRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4J1</accession>
    <name>C1N4J1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cilia- and flagella-associated protein 263</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_4254</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CFAP263 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063007.1">
        <property type="nucleotide sequence ID" value="XM_003062961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4J1"/>
    <dbReference type="STRING" id="564608.C1N4J1"/>
    <dbReference type="GeneID" id="9688447"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4254"/>
    <dbReference type="eggNOG" id="ENOG502QU7J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MFESFIC"/>
    <dbReference type="OrthoDB" id="10259713at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051885">
        <property type="entry name" value="CC_CF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025254">
        <property type="entry name" value="CCDC113/CCDC96_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15654:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15654">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13870">
        <property type="entry name" value="CCDC113_CCDC96_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="3 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCDC113/CCDC96 coiled-coil" evidence="9">
        <location>
            <begin position="82"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="94"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="251" mass="28575" checksum="E783F0C9F7ECDF22" modified="2009-05-26" version="1" fragment="single">LELSAADKLRVATTEHERAEAAVTRAEENGEKRLGDLRARLEETELRVAETKRETFEFKRDVVLGAIAAERVQRAMEQSIHAKDSDVGKLALKNSTLKAQVAMAESQLKQKEEQGDALHPIDFEQLKIEHEQYVRKIEEKNAELLRLKRATGNVVEQLSKTKRKLSDTIKRGTWLRDQMIFKRQLSATFDEALKRAAVEHAAARRTNKLLNTTASSDENPAVTDYLHAKRAATEWEKKAGDYERKLEVAEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4S3</accession>
    <name>C1N4S3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cation diffusion facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_52662</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062842.1">
        <property type="nucleotide sequence ID" value="XM_003062796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4S3"/>
    <dbReference type="STRING" id="564608.C1N4S3"/>
    <dbReference type="GeneID" id="9688487"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52662"/>
    <dbReference type="eggNOG" id="KOG1485">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAGDRPW"/>
    <dbReference type="OrthoDB" id="78296at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1350:FF:000001">
        <property type="entry name" value="Metal tolerance protein 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000005">
        <property type="entry name" value="Putative Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF13">
        <property type="entry name" value="CATION EFFLUX PROTEIN CYTOPLASMIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="138"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="11">
        <location>
            <begin position="349"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="418"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH52781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="442" mass="49025" checksum="EA41EB4DAD46F1EA" modified="2009-05-26" version="1">MSSSGSLRALAVETTADETTVVLPPSSVPGASSSRSKNLRDGNMSFRKSPDSWRLSADAFDTHKKTAEEFQGLRSRKAKSGVMAYYRKQNALVDQFGEIETLIAATDATGAPILASDEDAAEKTRGDAKREKREEFALQISFWANVLLLGIKTYAAVVSGSLSIMTSALDSFLDLVSGLILYLTERNMKKSNKYMYPAGKSRMQPLGIIVFSCIMGTLGFQIMIEGVRQLVGETHTHHLEDLWAVLGIMVSVIVVKFCLYLFCRNSQNEAVLTYAQDHRNDVMTNSVGLAAAIAGDKLYFWIDPLGAILLASYIVYNWSCTALENVKAMVGVSAPPEFLTQLTYLAWNHHEDIVCIDTVRAYTFGPNYFVEVDVVLPEEMPLRRAHDIGESLQNRIEEMEDVERAFVHIDFETAHYPEHAEATRADRERRRAAARATAISPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N589</accession>
    <name>C1N589_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52851</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063129.1">
        <property type="nucleotide sequence ID" value="XM_003063083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N589"/>
    <dbReference type="GeneID" id="9688366"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52851"/>
    <dbReference type="eggNOG" id="ENOG502R2ZH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VFTACWN"/>
    <dbReference type="OrthoDB" id="3700at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34118">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34118:SF6">
        <property type="entry name" value="PROTEIN CONSERVED ONLY IN THE GREEN LINEAGE 160, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="152" mass="16197" checksum="7AB98041C2E3B298" modified="2009-05-26" version="1">MYGAGLTAYATLGYGLASGLSAGLGVAGSLAYLILLGRYVDSLKEKEDDEEDYYAVNLVYEPVTDVGAMLGGAFGKVGAVYSQALLQKRLLVPVFLVVFATTFNKLDAPFDFNYGPVLLGFLTYKAAVLTKVYEDLKPALISALKGEDGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5D3</accession>
    <name>C1N5D3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Heat shock transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_48763</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the HSF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062948.1">
        <property type="nucleotide sequence ID" value="XM_003062902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5D3"/>
    <dbReference type="STRING" id="564608.C1N5D3"/>
    <dbReference type="GeneID" id="9688591"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48763"/>
    <dbReference type="eggNOG" id="KOG0627">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HSDRFEF"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000037">
        <property type="entry name" value="Heat stress transcription factor B-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0346">Stress response</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="11">
        <location>
            <begin position="30"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="117"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="271"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="406"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="430"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH52887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="506" mass="52842" checksum="AF82FC6B56681018" modified="2009-05-26" version="1">MSAATAAGSKGFSAQPGSATGATTPFATVNVSPFLWKTWNLVSDASSDHIISWSANGRTFTVWQPDLLETEHLPNTFKHSNFASFVRQLNNYGFRKCHSDRFEFGVEGFEQGKPELLTSLRRHDAPRNKKGGDAKGGGGKAAAGSASAANARGGGGAKKKNLMEGTPDHGAQSLEIGAYGGITSEVEQLKRDRLLLLKEVMRLRDVQNNTTEEVRRLSARLQATEQFQSQMMSFVEAVQQQGGGANGLAGSFGNADEMIARFGGSLGPRKAARKRRQMFLPSSSSGGGGGGSGGGGGGGVAGAGVDATRSAIQEVQDEIDEIDDALMTAQAYGPLSPNPHAAIQLPENEGAWLDMLGGGDDDDALVDGVDLTPASPPRVHVGGQRVRQSPLITSMSDVDLALAAAASGGSGGNSPGETAVDDADAADQAAARRGERQRDPHPQPDAFVANILNRGPSLEKQLSLGFLDHMDSADIGEMVRDMNIGVGSGGSDEFTRRVDALSDVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5R3</accession>
    <name>C1N5R3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nit2-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_53007</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063204.1">
        <property type="nucleotide sequence ID" value="XM_003063158.1"/>
    </dbReference>
    <dbReference type="SMR" id="C1N5R3"/>
    <dbReference type="STRING" id="564608.C1N5R3"/>
    <dbReference type="GeneID" id="9688846"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53007"/>
    <dbReference type="eggNOG" id="ENOG502QRQ2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HAIKLMV"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045012">
        <property type="entry name" value="NLP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055081">
        <property type="entry name" value="NLP1-9_GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003035">
        <property type="entry name" value="RWP-RK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32002">
        <property type="entry name" value="PROTEIN NLP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32002:SF41">
        <property type="entry name" value="PROTEIN NLP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22922">
        <property type="entry name" value="GAF_NLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02042">
        <property type="entry name" value="RWP-RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51519">
        <property type="entry name" value="RWP_RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RWP-RK" evidence="6">
        <location>
            <begin position="645"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="7">
        <location>
            <begin position="1101"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="116"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="602"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="728"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1002"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="602"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="735"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="779"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="842"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1021"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1045"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1086"/>
            <end position="1100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1322" mass="135056" checksum="414198597F494FD2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5X2</accession>
    <name>C1N5X2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53078</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063232.1">
        <property type="nucleotide sequence ID" value="XM_003063186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5X2"/>
    <dbReference type="GeneID" id="9688672"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53078"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="669" mass="68649" checksum="1F4094CE45407D77" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6H1</accession>
    <name>C1N6H1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53285</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063337.1">
        <property type="nucleotide sequence ID" value="XM_003063291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6H1"/>
    <dbReference type="GeneID" id="9688777"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53285"/>
    <dbReference type="OrthoDB" id="497760at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="247" mass="26637" checksum="B44CA1D93569A334" modified="2009-05-26" version="1">MKDSRRRATRGRISLAASRASPRDDDGGPSPPPSPSSSSFADDLASATGDVPDDVEAATATRDANARSEALLAARAVDASRELPPDTIAPMPEWLYDRRLDIVPAVFGRLNPFSGVLVYYTGAVLGECGGAPLVALQWIAFVFAPALAATASLRYFWRERRIRRRRERAAAKGASPPPPEYPWARSCRPAWLDIHLGYALLLPAGAAGGEGASWWLLLAPAFMAIRFVGGLRRVHIYTGPRTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6X5</accession>
    <name>C1N6X5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">15-cis-phytoene synthase</fullName>
            <ecNumber evidence="3">2.5.1.32</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PSY2</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_22804</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 (2E,6E,10E)-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34475"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="EC" id="2.5.1.32"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.32" evidence="3"/>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063807.1">
        <property type="nucleotide sequence ID" value="XM_003063761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6X5"/>
    <dbReference type="STRING" id="564608.C1N6X5"/>
    <dbReference type="GeneID" id="9689071"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22804"/>
    <dbReference type="eggNOG" id="KOG1459">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HIVAFFD"/>
    <dbReference type="OrthoDB" id="6600518at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046905">
        <property type="term" value="F:15-cis-phytoene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:geranylgeranyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31480">
        <property type="entry name" value="BIFUNCTIONAL LYCOPENE CYCLASE/PHYTOENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="356" mass="36894" checksum="514B0AC3BD64D26B" modified="2009-05-26" version="1">MASSATALAATTAAPRRAPSRSIAARASARRASSARASSSSSSSSSSIDDAAVAAAYDACAAATRASSATFYFATALMRPTQRERVRAIYAWCRALDEVVDGAETRSPADARRELDAIERRLRALFDDDDGGDGASSPPSSSGSSSSSPETIALADTIRATDGMSPEPFLDMIAGMRSDLPAAVPSSGAFYTLYCYDVAGTVGLMTLPVMGVAEGYGLDDAIPPGVELGIALQLVNVLRDVGEDAKRGRLYLPLDAVHAAGLTAEEILSGAVVNAVDGSVDARAEAHFARARVGIKMLPPAARLPVTAAGEIYGALLNKVRANGYDNITRRAYTTTGEKLRALPGLAARAWFGSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N772</accession>
    <name>C1N772_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_8872</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063685.1">
        <property type="nucleotide sequence ID" value="XM_003063639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N772"/>
    <dbReference type="STRING" id="564608.C1N772"/>
    <dbReference type="GeneID" id="9689126"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8872"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MARIQSM"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="41"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="151" mass="17281" checksum="5A53E48A9FD8FC2F" modified="2009-05-26" version="1" fragment="single">LRDIFAQFDRDQSGNITHDELKHVVKNLDGTGFISPSELRYLRENIDDIIADIDKDGDGEINYGEFVDMMIHLKEQFKQQDMRELFRTFDKDNSGSITAAELRKAVSQLDGIGLMSVMEQREMMENLDAMINEADTDGDGTVDYEEFVAMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1N791</accession>
    <name>C1N791_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">60S acidic ribosomal protein P0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_48999</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Ribosomal protein P0 is the functional equivalent of E.coli protein L10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063696.1">
        <property type="nucleotide sequence ID" value="XM_003063650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N791"/>
    <dbReference type="STRING" id="564608.C1N791"/>
    <dbReference type="GeneID" id="9689298"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48999"/>
    <dbReference type="eggNOG" id="KOG0815">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ESHEYYE"/>
    <dbReference type="OrthoDB" id="10259902at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030670">
        <property type="entry name" value="uL10_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039087">
        <property type="entry name" value="L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="113"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="282"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="315" mass="33449" checksum="648EC8F4F5B47C11" modified="2009-05-26" version="1">MPSAAILKVKQAYNDRLCKLLDDHDRAFLVHADNVGSRQFMDIRAALRPVSHILMGKNTMMRKCIREYCERKGDDSWNTLADKLIGNVGIIFTTGDMAEVRKTIAEFVVPAPAKVNAIAPCEVVIPAGPTGMEPSQTGFFQVLNIATKINKGAIEILSDFKCVEAGEKVTSSAATLLGKMGFTPFTYGLEVQMVYDKGAIFDVKVLDISDDDITQMFGAGLKNVAALSLATGYATVAAVPHAIINGYKNVLAISIATDYTFDLAQKVKDYLANPGAFGGGGGGGGGGGAAAAAAKAPEPEPEEEEEEEAAFDLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7A7</accession>
    <name>C1N7A7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_65926</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063865.1">
        <property type="nucleotide sequence ID" value="XM_003063819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7A7"/>
    <dbReference type="STRING" id="564608.C1N7A7"/>
    <dbReference type="GeneID" id="9689306"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65926"/>
    <dbReference type="eggNOG" id="KOG1132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19182at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990918">
        <property type="term" value="P:double-strand break repair involved in meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF47">
        <property type="entry name" value="FANCONI ANEMIA GROUP J PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="253"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="380"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="168"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="668" mass="73948" checksum="FCF5FDA1A2F85E8A" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7D5</accession>
    <name>C1N7D5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53649</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063716.1">
        <property type="nucleotide sequence ID" value="XM_003063670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7D5"/>
    <dbReference type="GeneID" id="9689322"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53649"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="147" mass="16175" checksum="AF30E0D40DCE98D1" modified="2009-05-26" version="1">MATRVATETRAGSVRLDASPRAGRRDSPTTVPRPLRPPRASSTVDSSSSSPSPDSSISSHLSQSESSSYDSDAEEELERFDVDPFQKPLPRIDEQLFFALRDVAPDLVVGAVASVRIARRREAFGRSISRPRFCCYHTGPHTTPFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7W5</accession>
    <name>C1N7W5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_49080</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064163.1">
        <property type="nucleotide sequence ID" value="XM_003064117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7W5"/>
    <dbReference type="STRING" id="564608.C1N7W5"/>
    <dbReference type="GeneID" id="9689604"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49080"/>
    <dbReference type="eggNOG" id="KOG1073">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WYPPPGH"/>
    <dbReference type="OrthoDB" id="21539at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="7">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="DFDF" evidence="4">
        <location>
            <begin position="262"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="5">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="6">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="87"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="338"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="1">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="2">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="92"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="157"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="353"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="399" mass="41835" checksum="193894699251BC73" modified="2009-05-26" version="1">MAAQYIGSKISLISKSEIRYEGILYTIDTVDSSLALQNVRSFGTEGRKKNGPQIPQSTEIYDYIIFRGSDIKDLTMDQAVAAAPAAAPPVQQPVQQQRMAPPMQQYQQQPPQQQYQQPPPQQQYQQQPPRQQQAPAPAAAPANPWNRQPVMAPPAAAPARQTRPPPQQQQQRQAAPKPAPTVVPKAKPTSFAAAIGGGGGGAQPKGVPARVPQHTLGGGGGGGAVPAPRAGGRGGRGGAGVPAPRAGGRGPVPRPNVGGDGLLPTRMAVPTEDFDFVGAFAKFRKEAEAMRLQQEAAPTYVKDDFFDSMSCEALERQQQATQTGGRSRFAEMRRLDMDTFGAAGGQNHNQNRGGRGGQNNGGRGGQNNGGKGGFQQGGRGGGHQQGGRGGRGGGRGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Y3</accession>
    <name>C1N7Y3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">High mobility group family B protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_53875</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064172.1">
        <property type="nucleotide sequence ID" value="XM_003064126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Y3"/>
    <dbReference type="STRING" id="564608.C1N7Y3"/>
    <dbReference type="GeneID" id="9689613"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53875"/>
    <dbReference type="eggNOG" id="KOG0381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1946">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10567">
        <property type="entry name" value="SWIB-MDM2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF15">
        <property type="entry name" value="HMG BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="87"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="DM2" evidence="5">
        <location>
            <begin position="177"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="87"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="258" mass="28683" checksum="2BE7247EAD4FE9FE" modified="2009-05-26" version="1">MAPKKETKNALVVERLHVILADADLETMTVKNVQAKLESELKTDIERGTKRKADGSGGKAGKKSKDDKKGKKRGRGKGKDVTDPNKPKGPKGAYMCFVQIARPKINASQPGLKFAEIAKQLGEQWKSMDAPTRAKYDKLAEDDKLRYARDIAAYVPMDAAGLDQLRKEKQAKKSAGGLQKPYKCTPALTKFLGGDKTISRANLTSRLWSYFKSKELMDPANKRWVVADKQLKDLLGVDRFQGFTVSKYLSQHLLPMDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8C8</accession>
    <name>C1N8C8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66353</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064059.1">
        <property type="nucleotide sequence ID" value="XM_003064013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8C8"/>
    <dbReference type="GeneID" id="9689688"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66353"/>
    <dbReference type="eggNOG" id="ENOG502SVWS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="514192at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="286" mass="30437" checksum="EA886FE530DA92FC" modified="2009-05-26" version="1">MGKAKTFANLTYNAVHGAARQALRRWNVGFPRLGRKVVVGRVARKDENDFFHVSTGHKSDVSFHARELQRGLTKLAAEPLPSVGSKLHLMVRAIENPMGELELSNRERVKAERDAHVWEEIRRAYQRGGIVRGRVLNAVGGGYAVGIAGHVAFLPQQSVRVYEGKNVPPVGVLLPFKILTVRETIQNVVVEGPVLEPGTAKSERRARRWDLKKSARLAAEARRRDLSAAAPGGGGGTAGGGGGTAGVGGVKGGGGEDAKVSEEGEEEKPAAAAAWWKAPPTGGGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8D6</accession>
    <name>C1N8D6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54045</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064064.1">
        <property type="nucleotide sequence ID" value="XM_003064018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8D6"/>
    <dbReference type="GeneID" id="9689691"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54045"/>
    <dbReference type="OMA" id="WCASCAE"/>
    <dbReference type="OrthoDB" id="10475479at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="156" mass="16828" checksum="6ED297C5F6272307" modified="2009-05-26" version="1">MAPFRNPFEEMKKANEIKRAKKEKGVKDGLETLVDKVKARSISHWSPYDPVGVRGRETARERGFQAVLADVRDGVVARNYGNGGSWPEAAEARREMVCPRCGASTRDAVEAGEREAADDAAAAADPVELAKVGKHPLGWCASCAEGNRLLDTSGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1N916</accession>
    <name>C1N916_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_10373</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064536.1">
        <property type="nucleotide sequence ID" value="XM_003064490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N916"/>
    <dbReference type="STRING" id="564608.C1N916"/>
    <dbReference type="GeneID" id="9689820"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_10373"/>
    <dbReference type="eggNOG" id="KOG0519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AIASECI"/>
    <dbReference type="OrthoDB" id="21225at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF72">
        <property type="entry name" value="OSMOSENSING HISTIDINE PROTEIN KINASE SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="196"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="326" mass="35292" checksum="4BDA6919DF8E29ED" modified="2009-05-26" version="1" fragment="single">LARLVNNVLDFSKIEAGKMELEETPFSLRSLVKETSEIMRAQATRKGLALNVRVADDVPEVIRSDALKLKQILVNLISNSVKFTRVGSVALTVTVASDADATEEYLRFEVEDTGVGMTRDVLTRIFEPFEQANRSTNRTFGGTGLGLALSKSLVELYGGILCASSNAGRGSVFSFAVGTGGGLKNRDDLRGAGPISVLIAEDNALNRKILSSQLKCLGDFNVRHVVNGAEAVDVISSSEHDAYAFVIMDYQMPVMDGIEATRRIRQLEQDTGKPPVAIVGYTASVEQSVLRRAEEVGMDMVLSKPCSIPKLRALIKMILMAHDLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N974</accession>
    <name>C1N974_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4-toluene sulfonate uptake permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_54393</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064405.1">
        <property type="nucleotide sequence ID" value="XM_003064359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N974"/>
    <dbReference type="GeneID" id="9690009"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54393"/>
    <dbReference type="eggNOG" id="ENOG502QUWR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="497462at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051598">
        <property type="entry name" value="TSUP/Inactive_protease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43701">
        <property type="entry name" value="MEMBRANE TRANSPORTER PROTEIN MJ0441-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43701:SF2">
        <property type="entry name" value="MEMBRANE TRANSPORTER PROTEIN YJNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="464" mass="46988" checksum="1C2BB2212D7BAF22" modified="2009-05-26" version="1">MSAAKAATKVAATAAKCVSAPLKPGWQYFTAGCGTCAGSLSALTGLGGAVVFVPTCSKLGMTAKKIVGTTVVAVTCATTAGSYAYASNNVTDIPAAIAIGVVGAATTPFGQMIAKRISGKTLRKWCGGALLMCAPTAFVKKKTHKPVPGHPELDEPEGSPIMVGDSRPGGAAALALAGKADELVAKGGILAYLNKARSGSHRFPYDRSAAGLGGVGAADGKETSSGPRGITSSKPPPPVARSVDERGAIIRHVGGAWARVRTSARRSDGEAGDAKDDDDSRDNPRVVAGSPAESSKTRGGQDGGGGGGGGDATTTTEVGKSGNAWINMKEQFQERLDNANGSWTEALIAERENFLIGLAVGMIQGTVGVGGGVLVTTYMSMFSDMEVHRICATALMATLVTNTVVVTHHLREGNVRIRVAAVLGATAMAASYVTAKNVSLSVPETAIRGFIASALVASGASMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9F1</accession>
    <name>C1N9F1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54483</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064610.1">
        <property type="nucleotide sequence ID" value="XM_003064564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9F1"/>
    <dbReference type="GeneID" id="9689881"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54483"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="18655" checksum="34AD9073140A212C" modified="2009-05-26" version="1">MTMMRDEYDQTSRASTLRGLFTMHLPLFATWAKSQSVVPGGGDIVVTRDVVDAMSKEAANPRAFARLVQKTATPRTGNARAKARTSSSDPGGGVATVRAKDAFDFFHVVMDARADAATWSARAAAFDGDAKWNHASYKSTHSKVAAATSEEGWDRGGRSFASSSDESFPSEKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9G8</accession>
    <name>C1N9G8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_7807</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064616.1">
        <property type="nucleotide sequence ID" value="XM_003064570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9G8"/>
    <dbReference type="STRING" id="564608.C1N9G8"/>
    <dbReference type="GeneID" id="9690057"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7807"/>
    <dbReference type="OMA" id="GQRTHWH"/>
    <dbReference type="OrthoDB" id="19329at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36768">
        <property type="entry name" value="ATP-DEPENDENT HELICASE/DEOXYRIBONUCLEASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36768:SF1">
        <property type="entry name" value="ATP-DEPENDENT HELICASE_DEOXYRIBONUCLEASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="139" mass="16093" checksum="5860A60CADA94066" modified="2009-05-26" version="1" fragment="single">SRRAQFHGERTAWHDLLATHCPTFDRDGVVAVPLPRPTNLSDDDAYKIRLSFDSDRHHTDWMTVIPEKKEPPVPMIDVAFYVDDGRVVAVAAQVVPLPRAYLREHRALVAEHHDRGAWPKHVIVRYRWKKRFRVDVNGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9R4</accession>
    <name>C1N9R4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54593</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH50993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064659.1">
        <property type="nucleotide sequence ID" value="XM_003064613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9R4"/>
    <dbReference type="GeneID" id="9690100"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54593"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="274"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH50993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="414" mass="41224" checksum="1BF58CDBD7BA0323" modified="2009-05-26" version="1">MRGVGTPVKSAALAVVKTGTTPGTEAPGTPAAPNFSSQAPLAPAADAAAEWEAAVVRARRETADAREALSRANTAREVAEARAIEAEATTAKLMAMNGNLLDHYRAALEGRGDGGGGGGGGGGGSGAAAAALGGPEPLPGPGPGASSAETTTTTTTRDADADAGGRRRLELASSTTASRGGGGGGGDPRSTLGGFDDGGGAVYQPPRSSGGRRVGGASAPLAPPLRVHAPQQQRRPASSVAPPLTTTTRTGSSRLSSVSRVWRGGGGRLVAAAAAAAPPARGRLPGARAGPRPSTSNRPTTTKSLRNGVHHANAVVWEPVTTTTKTSDVAADDVARSLEREMHAMRAEYDALLRRMGGGDGGDVDVAAAATHPKEWADAATRAAVLAERMEAKGAQILQLARSTGRGLGALAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Y2</accession>
    <name>C1N9Y2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_54686</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064696.1">
        <property type="nucleotide sequence ID" value="XM_003064650.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9690137"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54686"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="1201"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="656"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="784"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="943"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1098"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="805"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="844"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="945"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="974"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1098"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1121"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1149"/>
            <end position="1178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1299" mass="140144" checksum="9F397B524D949080" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA42</accession>
    <name>C1NA42_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription elongation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_54753</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TFS-II family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064724.1">
        <property type="nucleotide sequence ID" value="XM_003064678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA42"/>
    <dbReference type="STRING" id="564608.C1NA42"/>
    <dbReference type="GeneID" id="9690285"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54753"/>
    <dbReference type="eggNOG" id="KOG1105">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NPHEAFY"/>
    <dbReference type="OrthoDB" id="44867at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13749">
        <property type="entry name" value="Zn-ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000001">
        <property type="entry name" value="Probable Transcription elongation factor S-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035100">
        <property type="entry name" value="TF_IIS-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006289">
        <property type="entry name" value="TFSII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01385">
        <property type="entry name" value="TFSII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF0">
        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006704">
        <property type="entry name" value="TF_IIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS central" evidence="10">
        <location>
            <begin position="161"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="9">
        <location>
            <begin position="283"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="98"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="251"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="114"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH51058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="325" mass="34785" checksum="EF1C30DCAC2D3142" modified="2009-05-26" version="1">MTASVSAADVNEAYASLAKASEDAGSNTASEDRCVDVLKTLAAMKVPVKLFVSGEVGDAAKAIKKLAKKGPTDAIKAEASACVAAWKKIMLGAVEGGEDKDKEDADAAAATTTTKKEVEGGESGGAKKEEEDGDGDGEKKDASDGETNLKKLLEPALGDPLRDRTRELLAEAIAQAIGAPDVYASVEDVAQTAIAIENAMHAQWSDTGKEYKAKFRQLSFNLKDPKNPDLRRSVADGLISPAVLLDLSPEELGSDERRNSNAKIREHATNEAVRGQKKEASTDAFKCGKCKQRKCTYYQLQTRSADEPMTTFVTCVNCDNRWKFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA86</accession>
    <name>C1NA86_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54801</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064749.1">
        <property type="nucleotide sequence ID" value="XM_003064703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA86"/>
    <dbReference type="GeneID" id="9690304"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54801"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="10"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="72" mass="7683" checksum="5A0575DB54FD347E" modified="2009-05-26" version="1">MKLSPLAHQTSAHADAVWSVAWCPTGDDDGGDLLLTGSVDESVKSWRATAEGLEMVHDYQGETASHTTPSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAB5</accession>
    <name>C1NAB5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54831</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064875.1">
        <property type="nucleotide sequence ID" value="XM_003064829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAB5"/>
    <dbReference type="GeneID" id="9690377"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54831"/>
    <dbReference type="eggNOG" id="ENOG502RUZB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="501406at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF2">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912414" evidence="1">
        <location>
            <begin position="28"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="122"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH50855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="465" mass="52023" checksum="5A99244AA32EDAEF" modified="2009-05-26" version="1">MSCFTPRAVRLLTFFSAILLLLSVVSKSRKRALSNYVVSRKRDPALASRVDAILERSRLVRETMSASGGNFSTVVKTTARRCDTLLSSSSRKKFSKSQDKEDQFLEDSFFKGVCEGTYVELGGLDGVKFSNTHMFHHGLRWRGVLIEPSPRNFARLTENRPRDELYNAAVCAQHSQVHFIEALNSVSNGASSGVLEFMAPSFVEHWKDRLTATGSTLTKIECMPLSDILLKSDAGRTHVDMLSLDVEGAELEVLRTLDFDKHQFGVIFYEADEHDPVKYASYLGPDALPKGVTLGSIVTKSRPEAPRSCVEAVQYANFRWYDLGGSGSSSKNGVYTEEVLSQLRYRQDVDIARREYETRHRVTFEWIVNPRPDNVFVNPIPILSEVNSAKLYVPSWGHGYDSRSLSEDKRRVGINDRFSFGGREVMGKYNELYGVLCGGSGAGGKKLSIRAREALDAVITRDSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAC4</accession>
    <name>C1NAC4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 17 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_70792</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064880.1">
        <property type="nucleotide sequence ID" value="XM_003064834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAC4"/>
    <dbReference type="GeneID" id="9690381"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70792"/>
    <dbReference type="eggNOG" id="ENOG502QPVW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WRASIHQ"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003830">
        <property type="term" value="F:beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006813">
        <property type="entry name" value="Glyco_trans_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224:SF0">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04724">
        <property type="entry name" value="Glyco_transf_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="371" mass="42637" checksum="D7D8AA10C25F169E" modified="2009-05-26" version="1">MGAVKYSAASRFFLLLRAGMKPFRKKYFNNSVILSIQVYVSLCVFTCILCFRVLPERYFEWSSRRLCLSAAGSSSKSGVKLAAGHTRGYQQVYDLFLFNDELDMLEIRINELKDAVDYFVVVEARVSFTNMPKPLHFSENKDRFNAVSSKIVHIILDVLSGNSTWEREASHRNALLDLGLHQPGKEVRRGDIVIMSDVDEIPRSAVIVAMKKCPEIHGRVVVLELGLFYYSYLTRAREPWSVPMALQHPGPNVSLNSTLLRKTNTSATEVVRFRNAGWHCSYCFSTLASFRNKMQSFSHEEYNLPEYFEKDHVVRSVQAGVSLFDHLEPDYFKQLQRPDAPRFVREHARRFQYLLNRRSKNAGLSDIPTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAM3</accession>
    <name>C1NAM3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43752</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663754">
        <property type="protein sequence ID" value="EEH50847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064989.1">
        <property type="nucleotide sequence ID" value="XM_003064943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAM3"/>
    <dbReference type="GeneID" id="9690430"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43752"/>
    <dbReference type="OMA" id="MPARSAY"/>
    <dbReference type="OrthoDB" id="502233at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912421" evidence="2">
        <location>
            <begin position="23"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH50847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="589" mass="64048" checksum="8DEA0DC8D32D7A00" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGH7</accession>
    <name>C1MGH7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDAN1-interacting nuclease 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_49817</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054777.1">
        <property type="nucleotide sequence ID" value="XM_003054731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGH7"/>
    <dbReference type="STRING" id="564608.C1MGH7"/>
    <dbReference type="GeneID" id="9680194"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49817"/>
    <dbReference type="eggNOG" id="ENOG502R9SY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CYWNRFG"/>
    <dbReference type="OrthoDB" id="1272at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029404">
        <property type="entry name" value="CDIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31661:SF1">
        <property type="entry name" value="CDAN1-INTERACTING NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31661">
        <property type="entry name" value="SIMILAR TO CDNA SEQUENCE BC052040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14811">
        <property type="entry name" value="TPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="291" mass="31957" checksum="220CFD5E0731C1B9" modified="2009-05-26" version="1">MKLAEYEEIRAHITSLPSDVFPDADALRAKHPSASLDALVSIYSQESSRRVRGAHGKHLRAIGSHAARYVAGEDVFRIAADIDFPPCQLVRLLLEHLLGLGHKAVGPCLRDPFGKIPSSPPPESPAARGVPGVPGVPGSAICDRLKVDVERCVAWDHVASPAVDVMRHAAGREYEILLERRLEELRVPFVTEDALRAEGHAKTPDVKLTLPIAVNGRIVNWIDSKASFLDPIVHVERGVDQFQGYVNRFGPGMVIYWLGVIDELAEESDGDVFIVDDFPGDMEITKLKLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGR8</accession>
    <name>C1MGR8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_46130</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054824.1">
        <property type="nucleotide sequence ID" value="XM_003054778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGR8"/>
    <dbReference type="STRING" id="564608.C1MGR8"/>
    <dbReference type="GeneID" id="9680899"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46130"/>
    <dbReference type="eggNOG" id="KOG1116">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FAQNTRC"/>
    <dbReference type="OrthoDB" id="530923at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF54">
        <property type="entry name" value="SPHINGOSINE KINASE RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="6">
        <location>
            <begin position="79"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="397" mass="42208" checksum="2C43DDACD5770938" modified="2009-05-26" version="1">MLKLALATTAISMCMRRGVGAKKKKQQKMDPFDDISGIPALRPSKSDRAVSLDPKTPRLRHPVGGANTNANASANASAKKIKTILLVLHGVKSKERKGERQVNNVRARALLQDIALIEVVTERAGHCEELVRDASLRGVDAVGVMGGDGSLREGVCGMLARPASDRRPVFVFPVGTGNNFARDLGHRDVKDAFDAIGRGVERAVDVVKVTHPGGSTYSVNCVTWGMARDAAETAEKMRWMGPVRYDVAGFYHIAKGKANLAKITASDDGAGGGDAAAAAGKGGGEGDGAYDDYMMMFAQNTRCSGRNFKFTPSAELDDGKFDVVAVRKCGMFKTIGLFDKVKADGAHVEDPDVCYVKATRATLDAKDASDLVGIDGEVNVKSPVTLEAIKHAFTTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHC7</accession>
    <name>C1MHC7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_8235</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054935.1">
        <property type="nucleotide sequence ID" value="XM_003054889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHC7"/>
    <dbReference type="GeneID" id="9680970"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8235"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="82" mass="8745" checksum="F1216AE82F676C71" modified="2009-05-26" version="1" fragment="single">SCGTGALDGCGRMMCSLCESRNTSKCSGNCGSSMCTDCWDNEMDDSRMCCVPGCTERYCGPCHDGFARIATCDGYECGRDCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHK6</accession>
    <name>C1MHK6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Uroporphyrinogen-III synthase</fullName>
            <ecNumber evidence="3 7">4.2.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HEMD</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_50233</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>hydroxymethylbilane = uroporphyrinogen III + H2O</text>
            <dbReference type="Rhea" id="RHEA:18965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="EC" id="4.2.1.75"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the uroporphyrinogen-III synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.75" evidence="3 7"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054970.1">
        <property type="nucleotide sequence ID" value="XM_003054924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHK6"/>
    <dbReference type="STRING" id="564608.C1MHK6"/>
    <dbReference type="GeneID" id="9680695"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50233"/>
    <dbReference type="eggNOG" id="ENOG502QST9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WVESIME"/>
    <dbReference type="OrthoDB" id="443551at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38042">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38042:SF1">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="HemD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrapyrrole biosynthesis uroporphyrinogen III synthase" evidence="8">
        <location>
            <begin position="91"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="348" mass="36036" checksum="2E2DEE68DD82646A" modified="2009-05-26" version="1">MSRASCTSPTAAATRSYVTSVQFARGQGAAGALKTKIVGVAFVTRSSSGRYCRGPLMNAVPTGMAAVDVSETSYAGRRVVLTRESGKNGDMMERLTRRGIECVEMPLIETAVGADAPSLPSALNDPEGWTWVCITSPEAAAVFLRGWEQAGQPDVAIATVGKGTAKVLKPAYDAGKLRARTFTPSKANAETLVAELPLDADDASAPAAPRVLYPASAKAASTLQDGLAKRGAIVTRLNTYSTEKVTAVDEDVLTRAKTADVVTFGSPSAVKAWVSLSGFDSDTPAETHPAYACIGGTSAKACDAVGIPNVMFAENPGLDGWELVVCKALDGARERSGAGGGDRTQSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHR7</accession>
    <name>C1MHR7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_50297</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055001.1">
        <property type="nucleotide sequence ID" value="XM_003054955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHR7"/>
    <dbReference type="STRING" id="564608.C1MHR7"/>
    <dbReference type="GeneID" id="9680923"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50297"/>
    <dbReference type="eggNOG" id="ENOG502SGVZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HADNQHY"/>
    <dbReference type="OrthoDB" id="449052at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF128">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="166"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="264"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="347" mass="36873" checksum="3B36BDC97C86BF8B" modified="2009-05-26" version="1">MRVQSAPLVTMHADNQHYDAQCFLSVGDLCLGLLERVAVEGANTSNALTVLTRMAALTKIGQKYGKTNLLDVRSKWDGTGVWAAATEDMSLSDALRRCLHIGREESPGSPMLRQCPHRFAVIDASGIVTDIVAQSDIAMYLRRNIDLLDPSIVDATVKALGLGSQGSRRVVTVEASTPTIDCFQLMQSSNVQAVAVVDDGTDAIVGNLSETDLMPLQCDAYGALALPVGEFLVHAHLIVPKLDNDRMLYSPQTTAFGAALMCAGKRLTVTVTPDATVREILDLMHTRAVHRVWVVDDARRPTGVIALSDVLAAIAVEVAGAGETDTAKSMARSTGTTTTTAATSSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI64</accession>
    <name>C1MI64_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50451</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055613.1">
        <property type="nucleotide sequence ID" value="XM_003055567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI64"/>
    <dbReference type="STRING" id="564608.C1MI64"/>
    <dbReference type="GeneID" id="9680933"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50451"/>
    <dbReference type="OMA" id="DDAWIVE"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910471" evidence="1">
        <location>
            <begin position="25"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="14"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="162" mass="16820" checksum="627E652F5780CB1B" modified="2009-05-26" version="1">MRGLLVNLALLFAALLVATSPAVAADPASGARVDASNFDAIVAASDAAFVVKVHSPRCGTCQEMRPTWDALVAARSNDVKFATVDIDDDRGMKLAVELGVLDDGVPAVWGFDRAAEGERSTPRKLWSGYDAPSARELAAATFEGGGVDLNGARNADGFVAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ71</accession>
    <name>C1MJ71_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_61839</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055782.1">
        <property type="nucleotide sequence ID" value="XM_003055736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ71"/>
    <dbReference type="STRING" id="564608.C1MJ71"/>
    <dbReference type="GeneID" id="9681075"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61839"/>
    <dbReference type="eggNOG" id="KOG1203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AMEHEEC"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF11">
        <property type="entry name" value="OS06G0360300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-binding" evidence="3">
        <location>
            <begin position="100"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH61034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="411" mass="43261" checksum="F8881E03D04D10FF" modified="2009-05-26" version="1">MMAATIAARSRALAPCARPRAARERRSRGGVAPAARPRFDRATRVASFPSSESEARRVSRIVRTRASSSDDADATCDPVGRGPCGAIPGLKSDEVVLVVGGAGRVGRRLVSTLVNCGVRVRVMTRDADSVAARELASKFSDATSSALLEIVEGDVTDDDDARIERAVAGCTRVVACHGAERIARVADLFSRPELTDKRHPRFVNYLGVERLAKAAAKTKSVRRFVRVTGMSVGYAPMHPIAVLLNVVLSMSIQWQLAGEVATRSIVAAAGKEYAVVRPGNLSDAPRPENSVVIIGHGGAHVRAGKPSAANATVCVAGAATASGGVRSEMSWDPARGMHYKTVETDSVVQEGTDVTGMVLQVSADEDELDADVNHRRWVGIFLFGVVGAAAAAARALASLATWFMRLSAGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKA2</accession>
    <name>C1MKA2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Jumonji domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">JMJH</name>
        <name evidence="4" type="ORF">MICPUCDRAFT_70681</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055961.1">
        <property type="nucleotide sequence ID" value="XM_003055915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKA2"/>
    <dbReference type="GeneID" id="9681322"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70681"/>
    <dbReference type="eggNOG" id="KOG2132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WIGTKNT"/>
    <dbReference type="OrthoDB" id="47172at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF101">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="546"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="449"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="687" mass="74053" checksum="4F8BBBBA5B688A3D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKJ1</accession>
    <name>C1MKJ1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_13754</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056006.1">
        <property type="nucleotide sequence ID" value="XM_003055960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKJ1"/>
    <dbReference type="STRING" id="564608.C1MKJ1"/>
    <dbReference type="GeneID" id="9681342"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13754"/>
    <dbReference type="eggNOG" id="KOG1531">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EVYIIYT"/>
    <dbReference type="OrthoDB" id="239812at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.80:FF:000001">
        <property type="entry name" value="ATP synthase gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.80">
        <property type="entry name" value="ATP synthase, gamma subunit, helix hairpin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="ATP SYNTHASE GAMMA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693:SF22">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT GAMMA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039089">
        <property type="entry name" value="ATP_synthase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="ATP synthase (F1-ATPase), gamma subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="295" mass="31625" checksum="F3FDB8D7C861DF8C" modified="2009-05-26" version="1">MPNFNLFPLVSPAVPHGSRLISLQVVAQRMKSVGNIQKITAAMKMVAASRLKGAQTKMEKSRGLVEPMVRLLGDQPGVDAERTLLVPVSSDKGLCGGINSTVVKYSKVVAGLSGAQVPLLTIIGEKARGQLSKAYAETLTGAIVDLSKVPLTFATASLVSDTILNQGAGKHQIVYNRFQSVISFKPTVATVYSSGEYEKAAESGMNNFDAYELEGPERSEFLLDLSEFNMGVVVYNALLENSTSELGSRMQSMENSTKNAKDMLGKLTLLYNRTRQASITTELIEIISGASALEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML00</accession>
    <name>C1ML00_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_5184</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPC synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056473.1">
        <property type="nucleotide sequence ID" value="XM_003056427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML00"/>
    <dbReference type="STRING" id="564608.C1ML00"/>
    <dbReference type="GeneID" id="9681383"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5184"/>
    <dbReference type="eggNOG" id="KOG2728">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTIRRCN"/>
    <dbReference type="OrthoDB" id="70224at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/pantothenate metabolism flavoprotein C-terminal" evidence="3">
        <location>
            <begin position="58"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="DNA/pantothenate metabolism flavoprotein C-terminal" evidence="3">
        <location>
            <begin position="187"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="284" mass="31085" checksum="EB2E53FDADBC2496" modified="2009-05-26" version="1" fragment="single">ANAFFASAPPIPRVDTVKRDAARFVRHHGHANAFDDATTLPGGASARPPRGTPRPIALVTSGGTTAPLERSAVRFIDNFSSGTRGAASAECLLERGYAVIFLHRAGSMRPFERSLETAAELAGAGTAAEEVEATSNAAVHLMPLVRRYHAAKTKRTLLMVPFTSVFEYLTLLRTLCVELRACGARAMTYLAAAVSDFYVPWDRLSTHKIQSRGITLTLRLEQTPKMLALVRSKWCPKAFGASFKLETDVEILLQKSRDSLRKYGMHVVVANEMTQRKDEVVLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML88</accession>
    <name>C1ML88_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55621</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056516.1">
        <property type="nucleotide sequence ID" value="XM_003056470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML88"/>
    <dbReference type="STRING" id="564608.C1ML88"/>
    <dbReference type="GeneID" id="9682011"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55621"/>
    <dbReference type="OMA" id="FKAWRGW"/>
    <dbReference type="OrthoDB" id="566935at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="689"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="549"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="703"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="757" mass="87953" checksum="C1283FA458A0E310" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLG4</accession>
    <name>C1MLG4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal peptidase complex catalytic subunit SEC11</fullName>
            <ecNumber evidence="4">3.4.21.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Signal peptidase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase complex catalytic subunit sec11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MICPUCDRAFT_49482</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S26B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="4"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056560.1">
        <property type="nucleotide sequence ID" value="XM_003056514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLG4"/>
    <dbReference type="STRING" id="564608.C1MLG4"/>
    <dbReference type="MEROPS" id="S26.010"/>
    <dbReference type="GeneID" id="9681790"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49482"/>
    <dbReference type="eggNOG" id="KOG3342">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ILMNEYP"/>
    <dbReference type="OrthoDB" id="10257561at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009003">
        <property type="term" value="F:signal peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001733">
        <property type="entry name" value="Peptidase_S26B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02228">
        <property type="entry name" value="sigpep_I_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806:SF6">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00728">
        <property type="entry name" value="SIGNALPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S24/S26A/S26B/S26C" evidence="17">
        <location>
            <begin position="33"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00045533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH59936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="19065" checksum="590D36D9F7D2FE51" modified="2009-05-26" version="1">MISELCSLNRRQLVLQILGLGLVITSALVIWRSLVYLTNSESPMVVVLSGSMEPAFFRGDILFLNHSKRSISVGEVIVFNIEGRKIPIVHRVISSYSGKTLNNTNYLTKGDNNFGDDTVLYAAGQPTLSTDNIVGGVAAFIPCIGRITIIMNDFPILKYSVIGILCFLVVLSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLL9</accession>
    <name>C1MLL9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_4259</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056588.1">
        <property type="nucleotide sequence ID" value="XM_003056542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLL9"/>
    <dbReference type="STRING" id="564608.C1MLL9"/>
    <dbReference type="GeneID" id="9681850"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4259"/>
    <dbReference type="eggNOG" id="ENOG502QTQ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QYVLLHV"/>
    <dbReference type="OrthoDB" id="2019294at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16914">
        <property type="entry name" value="EcfT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33514">
        <property type="entry name" value="PROTEIN ABCI12, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33514:SF13">
        <property type="entry name" value="PROTEIN ABCI12, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="277" mass="30336" checksum="FBC32AA0D7E6C4BF" modified="2009-05-26" version="1" fragment="single">PLGTYVSNHSSALHRLDPRLKQAWLATMLLLPQRGSLAEKSTVCLVLAFSTAAALPYRVWRPQLSVVTKVCSLIFFIAVLGSESVIPLVGPREPSAFYEGLLDIPTFKNCYYNTLFHFGPLQISQRNFSLAMSASCIAFTALQSAQLSLCTTTPEGMIWALRWYLKPLLLIGVPVDGIVFTLLFSMRFTTTVFDEIRNICLGLVSRRIEWHGLNLTACVALFGSILLQTLNTLFLTSAAVSEALCARGFDSSSGHEFSNSLSASPSRAFDCTALLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLR2</accession>
    <name>C1MLR2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein axonemal intermediate chain 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">WD repeat-containing protein 78</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_25391</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Dynein axonemal particle</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056207.1">
        <property type="nucleotide sequence ID" value="XM_003056161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLR2"/>
    <dbReference type="STRING" id="564608.C1MLR2"/>
    <dbReference type="GeneID" id="9682059"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25391"/>
    <dbReference type="eggNOG" id="KOG1587">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="24670at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120293">
        <property type="term" value="C:dynein axonemal particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF12">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="526"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH59583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="669" mass="74193" checksum="B991D3F564A6F3A9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLT6</accession>
    <name>C1MLT6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56263</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057277.1">
        <property type="nucleotide sequence ID" value="XM_003057231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLT6"/>
    <dbReference type="GeneID" id="9682259"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56263"/>
    <dbReference type="OrthoDB" id="565209at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009943">
        <property type="entry name" value="DUF1475"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07343">
        <property type="entry name" value="DUF1475"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="151" mass="16597" checksum="E2BE18118C111B48" modified="2009-05-26" version="1">MWANGAGEDEEQRDALYARPGSTGADQGWGAGRGNPRGPFVNACAVLTALGAFTMFVVIAWAISSTTGSFGEQIAWLVSNPWGVVSLVDLYVGFSVFSLWIWFRERNAFAAAAWTLAMMTTGWLGGSAYVFNCLRQFNGDWQWFFMGNRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLY6</accession>
    <name>C1MLY6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">sulfiredoxin</fullName>
            <ecNumber evidence="2">1.8.98.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_9111</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>S-hydroxy-S-oxy-L-cysteinyl-[peroxiredoxin] + [protein]-dithiol + ATP = S-hydroxy-L-cysteinyl-[peroxiredoxin] + [protein]-disulfide + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17545"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="Rhea" id="RHEA-COMP:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:61973"/>
            <dbReference type="ChEBI" id="CHEBI:61974"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="1.8.98.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfiredoxin family.</text>
    </comment>
    <dbReference type="EC" id="1.8.98.2" evidence="2"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057302.1">
        <property type="nucleotide sequence ID" value="XM_003057256.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLY6"/>
    <dbReference type="STRING" id="564608.C1MLY6"/>
    <dbReference type="GeneID" id="9682284"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9111"/>
    <dbReference type="eggNOG" id="KOG3388">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CHRFEAC"/>
    <dbReference type="OrthoDB" id="10023328at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032542">
        <property type="term" value="F:sulfiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16395">
        <property type="entry name" value="Srx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1530.10">
        <property type="entry name" value="Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, ParB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016692">
        <property type="entry name" value="Sulfiredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21348">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21348:SF2">
        <property type="entry name" value="SULFIREDOXIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017267">
        <property type="entry name" value="Sulfiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="ParB/Sulfiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB-like N-terminal" evidence="11">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="49"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Interchain" evidence="10">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR017267-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR017267-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="81" mass="9281" checksum="26E6A9F4A0719D67" modified="2009-05-26" version="1" fragment="single">IDQIARPLGKTRANDQEKVKWLMESIADVGLQEPIDVLEVDGKYYGFSGCHRFEAHVKLGRETIECRVLKATRATLQMHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM17</accession>
    <name>C1MM17_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56365</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056860.1">
        <property type="nucleotide sequence ID" value="XM_003056814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM17"/>
    <dbReference type="GeneID" id="9682757"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56365"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="469" mass="49357" checksum="DE7E052965E306C8" modified="2009-05-26" version="1">MTNVHGAVADVPTDLASLLDVGGKPHAADVVSAPSLADALGTSSDAARGRTPAFEGRWFLKRSEHIRRWIRTWIALDASGTMLEMKNDALDVKPRAVVRVRDVRSVALSSVNFHGGKEHDGACVYVAISMRPNATTPGATPESGLYLVAETPSAAAEWVVDARRVAGLEMTASPAVLAPPGSGKFGRHVAKEAMRAVASTRGRGEEEPAPATPSPEPRGAVANRRGPRAPSSSVSSASSVETPGAASDASFSFAGSDSGSPTATVAAAAATPTPTPTPTSATSSPVLFARDAAPSAAAKSGGGTILRRILNPRARKEHALASSLCAVTERLRRAEAASRRELRETSAMATEALRAKDERCVALTRALELETHARAESSALLDALQRRLEESATALEKREAQLASTTAAAATLRAKYEKTKARSVICTLVPVRPRPRGDRRFLRTFLPGGRFSPLTPRFQSPPSKPFNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMF3</accession>
    <name>C1MMF3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_10838</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057395.1">
        <property type="nucleotide sequence ID" value="XM_003057349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMF3"/>
    <dbReference type="STRING" id="564608.C1MMF3"/>
    <dbReference type="GeneID" id="9682834"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_10838"/>
    <dbReference type="eggNOG" id="ENOG502QRIX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LGGCQGT"/>
    <dbReference type="OrthoDB" id="191364at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF11">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="28"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="328" mass="36130" checksum="893F60C94A1C70FE" modified="2009-05-26" version="1" fragment="single">LENGRVVRDVVLGYTAYGELNASGDNAIVVGHSLTSNSNVTEWWGAMCGPGEQFALNTLEDFVICVNYLGSPYGSSAPTTADPDKADGGCYGADFPTPVSIRDNVRLQKMLLDSLGVKHLKMAIGGSMGSMLALEWAATFPDFVEELCLIAGCGRHTDWAIGIGEAQRFSIMADGKFKGGSYDVNDPPKAGLATSRMMAMLSYRAPASVDQKFERTSLPYFAVESYLQYQGKKFIRRFDANCYIQLTYTLDSHDVARGRGEYRDVLRSLRHRVLVVGITSDVLYPFALQRELAREMPHSELYAIDSPHGHDAFLIEIASLNVAVTRWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMI0</accession>
    <name>C1MMI0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_56536</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056929.1">
        <property type="nucleotide sequence ID" value="XM_003056883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMI0"/>
    <dbReference type="STRING" id="564608.C1MMI0"/>
    <dbReference type="GeneID" id="9682368"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56536"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TSFRAHF"/>
    <dbReference type="OrthoDB" id="498515at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF298">
        <property type="entry name" value="MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="357"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="671"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="704" mass="74255" checksum="ED1AFADA19FDBC50" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMJ6</accession>
    <name>C1MMJ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_4070</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057417.1">
        <property type="nucleotide sequence ID" value="XM_003057371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMJ6"/>
    <dbReference type="STRING" id="564608.C1MMJ6"/>
    <dbReference type="GeneID" id="9682379"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4070"/>
    <dbReference type="eggNOG" id="KOG0374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NEVLWFM"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47680">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47680:SF2">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="306" mass="32166" checksum="0D8CAF15407156F2" modified="2009-05-26" version="1" fragment="single">RLVAVGDLHGDLAKTKEALVAGGLMDPSTERWSGGTTTAVQVGDQLDRGGDEVAILLLLERLRKEARDAGGELVVMNGNHETLNVAGRFRYATADGLEDFRRWRGRQCMGAAMKHACGRRTGAAAAAAAAAGDDAAAPGRTSARLYSDSGPGAQLPRLAALAPGGPMARRFLAHQPLVVAVGSTVFAHGGVLPHHVDYGLERINKETSDWVRGNKGSGPPPVHVSGRESVVWARDYSMPEKTQCDCDVLEASLSKMPGMKRVVVGHTIQAPHGVNAACDGKVLRVDVGMSKGCGDGKPEVLEILDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MML1</accession>
    <name>C1MML1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_7373</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056947.1">
        <property type="nucleotide sequence ID" value="XM_003056901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MML1"/>
    <dbReference type="STRING" id="564608.C1MML1"/>
    <dbReference type="GeneID" id="9682864"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7373"/>
    <dbReference type="eggNOG" id="KOG4208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="REEYNAP"/>
    <dbReference type="OrthoDB" id="21467at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12307">
        <property type="entry name" value="RRM_NIFK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46754">
        <property type="entry name" value="MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="6"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="151" mass="17691" checksum="CFCDB9740CA4BF3B" modified="2009-05-26" version="1" fragment="single">KETRAKTLYIGHVPHGFYEDQMRAYFGQFGEVTRLRLSRNKKTGRSKHYAYVEFKYPEVAEVVAQSMDGYLLFESIMKVKLMTPDECHPELWKGANRKFKTVPWQKKAAEKHDRALTEAETEKKNAALVKKERARRRKIEAAGIEYDFPGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMV4</accession>
    <name>C1MMV4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_32583</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056993.1">
        <property type="nucleotide sequence ID" value="XM_003056947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMV4"/>
    <dbReference type="STRING" id="564608.C1MMV4"/>
    <dbReference type="GeneID" id="9682911"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32583"/>
    <dbReference type="eggNOG" id="KOG2330">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PSHWCQK"/>
    <dbReference type="OrthoDB" id="10260794at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007180">
        <property type="entry name" value="DUF382"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006568">
        <property type="entry name" value="PSP_pro-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052584">
        <property type="entry name" value="U2_snRNP_Complex_Component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785">
        <property type="entry name" value="SPLICING FACTOR 3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785:SF6">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04037">
        <property type="entry name" value="DUF382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04046">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00581">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP proline-rich" evidence="1">
        <location>
            <begin position="153"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="235" mass="26597" checksum="003C2A1D8FF0CCAD" modified="2009-05-26" version="1" fragment="single">MSNKQKKLLARMKVAELKTHCSKPEVVEVWDTTAADPRLLVYLKAYRNTIPVPSHWCQKRKYLQGKRGLEKPPWQLPSFIEATGIQKLRDAYAEKEDTKKLKQKGKDAKTAKLGKIDIDYQVLHDAFFKFQTKPKMTKVGELYYEGKEYEMDLKGKKPGTLTEETREALGMTDDGPPPWLINMQRYGPPPSYPSLKIPGLSAPIPPGAQFGYHPGGWGKPPVDEYGTPIYGDVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNC9</accession>
    <name>C1MNC9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56871</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057558.1">
        <property type="nucleotide sequence ID" value="XM_003057512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNC9"/>
    <dbReference type="GeneID" id="9682521"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56871"/>
    <dbReference type="eggNOG" id="KOG2551">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SAQANHI"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="42"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="285" mass="29685" checksum="8ABFAEA0DF59E7B2" modified="2009-05-26" version="1">MDRAAAVASSARGVGASARAASPSRPPPPPRDVAVMSGGGGKLRVLALHSWRTSASIFAKQLAVAGWTNDDGTGLGDQCEFVCVDAPHPASGEIPRDVARAFEGPYYEWWDASRDDRDGSLRYVGDDASVAFVERVAREDGPFDGVVGFSQGATFAGLLAAIGAVDGRGPFAAVSAEAPPVFAILLSGMLARTSEAAATYAEAKDSPRHASIPTMHVIGAADRVMPPALSERLASEFADPVIVTHERGHVVPRLERDALATARNFLAARAAAAREARDGSPRSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNL1</accession>
    <name>C1MNL1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_25464</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. CGFS subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056668.1">
        <property type="nucleotide sequence ID" value="XM_003056622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNL1"/>
    <dbReference type="STRING" id="564608.C1MNL1"/>
    <dbReference type="GeneID" id="9682565"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25464"/>
    <dbReference type="eggNOG" id="KOG0911">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WAEPCKT"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000012">
        <property type="entry name" value="Monothiol glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF73">
        <property type="entry name" value="GLUTAREDOXIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="347" mass="36351" checksum="2245C2657B75AF69" modified="2009-05-26" version="1">MSLVDARSAAEHDALLARPNALVVTHFWASWCEPCGAMDALMRELAAARPAVTFARVEAEACDDLAERYDVSAVPFFTFHRGAEKIDALEGADARALAGRVRQHFGVGGAAAAAASAPAAAAAPAAAEPLDARLKRLTTQTPVVLFMKGTLDEPRCGFSRKVVDAVGATGIAFSTFDILSDEDVRQGLKEYSNWPTYPQLYANGELVGGCDIVLEMASDGSLKEALADAAAAAADADADAGGGDLNARLAALVKSEPVMLFMKGTRDEPRCGFSRKVVDAVGATGVPFGTFDILSDEDVRQGLKEYSNWPTYPQLYANGELVGGCDIVLEMASDGSLKEALAATVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNN4</accession>
    <name>C1MNN4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Formin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_55968</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the formin-like family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057139.1">
        <property type="nucleotide sequence ID" value="XM_003057093.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MNN4"/>
    <dbReference type="GeneID" id="9682578"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55968"/>
    <dbReference type="eggNOG" id="ENOG502S7JB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GMTCYEG"/>
    <dbReference type="OrthoDB" id="1668162at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051425">
        <property type="entry name" value="Formin_Homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725:SF1">
        <property type="entry name" value="DISHEVELLED ASSOCIATED ACTIVATOR OF MORPHOGENESIS, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725">
        <property type="entry name" value="FORMIN HOMOLOGY 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="5">
        <location>
            <begin position="106"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="559"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="FH2" evidence="6">
        <location>
            <begin position="1257"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="239"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="403"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="454"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="620"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="806"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1064"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1120"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1544"/>
            <end position="1571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="296"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="342"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="641"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="669"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="687"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="819"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="856"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="886"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="926"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="969"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="999"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1034"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1125"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1172"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1186"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1220"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1250"/>
            <end position="1259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1674" mass="173882" checksum="A76710B160E540AC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ91</accession>
    <name>C1MQ91_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_32935</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058086.1">
        <property type="nucleotide sequence ID" value="XM_003058040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ91"/>
    <dbReference type="STRING" id="564608.C1MQ91"/>
    <dbReference type="GeneID" id="9683155"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32935"/>
    <dbReference type="eggNOG" id="KOG1379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TTHATHK"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="259" mass="28075" checksum="D73786E7CF341EC5" modified="2009-05-26" version="1">MQREWGHGGEDAYFVKKVNIKRDDDGDGVDDTCVAFGVADGVYMWRQLGIDAGLYSRKLMGLCSDAFATVKTTEDDSFKPQKLLEAAYEGCTAEALKGSTTACVLTVDATHGVLRGANIGDSGFMIVRGAPGERECVHRSPPQEHEFGRPFQLGHHEASDKPFDAMLTTFQLDPGDVLIMGSDGLWDNLSESEIVELVEKVFNARVANAAAREIVTAAYAASMDKRRSTPYSLAATEFFDMVYSGGKKDDITVVVANVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ98</accession>
    <name>C1MQ98_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_67304</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057720.1">
        <property type="nucleotide sequence ID" value="XM_003057674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ98"/>
    <dbReference type="STRING" id="564608.C1MQ98"/>
    <dbReference type="GeneID" id="9683158"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67304"/>
    <dbReference type="eggNOG" id="ENOG502SCQT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NCDANQY"/>
    <dbReference type="OrthoDB" id="546201at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.220.10">
        <property type="entry name" value="Hormone Receptor, Insulin-like Growth Factor Receptor 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46104:SF1">
        <property type="entry name" value="GENE 9195-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46104">
        <property type="entry name" value="GENE 9195-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein kinase ephrin type A/B receptor-like" evidence="4">
        <location>
            <begin position="74"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="628"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="728" mass="74400" checksum="FBC4DDF8DC75E92F" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQB2</accession>
    <name>C1MQB2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_67320</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057726.1">
        <property type="nucleotide sequence ID" value="XM_003057680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQB2"/>
    <dbReference type="STRING" id="564608.C1MQB2"/>
    <dbReference type="GeneID" id="9683536"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67320"/>
    <dbReference type="eggNOG" id="ENOG502RGE2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RQHITFR"/>
    <dbReference type="OrthoDB" id="49058at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10142">
        <property type="entry name" value="HD_SAS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.210.20">
        <property type="entry name" value="Spindle assembly abnormal protein 6, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032396">
        <property type="entry name" value="SAS-6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038558">
        <property type="entry name" value="SAS-6_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34230">
        <property type="entry name" value="ASSEMBLY ABNORMAL PROTEIN 6, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34230:SF2">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16531">
        <property type="entry name" value="SAS-6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spindle assembly abnormal protein 6 N-terminal" evidence="1">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="213" mass="24049" checksum="E16B7A235D8A3789" modified="2009-05-26" version="1">MDFSQLEDADPSCADGSRVFYEREVPFELRSVDGLETPEEVGTLEAVRVKICVQGPDGAYTNVKIELCSESNLFFHYTHDLDTAAYAALQEGQRLMVDFKDYPAVIQRNLNNCIKQPHAFLAVLVMQKTGGARLDFIQNMEYKFVELLSIDLDSTPEEATRAHVTYRYNAMKGRLALCQARLADVNALVKIKNPSLLLQLKNEERSRKGVRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQM2</accession>
    <name>C1MQM2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_39367</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057783.1">
        <property type="nucleotide sequence ID" value="XM_003057737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQM2"/>
    <dbReference type="STRING" id="564608.C1MQM2"/>
    <dbReference type="GeneID" id="9683589"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39367"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ARSIWIF"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="465"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="589"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="661"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="465"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="589"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="2">
        <location>
            <position position="635"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="702" mass="73699" checksum="3B8991332C8E00EE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQP4</accession>
    <name>C1MQP4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_57363</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057795.1">
        <property type="nucleotide sequence ID" value="XM_003057749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQP4"/>
    <dbReference type="GeneID" id="9683599"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57363"/>
    <dbReference type="eggNOG" id="KOG1580">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YLQCSAF"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005459">
        <property type="term" value="F:UDP-galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005460">
        <property type="term" value="F:UDP-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF18">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="362" mass="37933" checksum="FE14E381D8002E11" modified="2009-05-26" version="1">MGAASSKKMAANKEAKLAVAVSGIFFAFSYFAVLQEDVYRASYAVPGAGRGATEKFTSTFLVLAVERGVNALAGAIGLALVGGSGIRVPRRQILTSGVSQMLAMASANEALRYVSYATQVLGKSCKMVPVMIGGVAAGRKFPRAQYLQVLAITLGVAVFNFGKKASSSGKGAGGDSAYGLGLIGASLVMDFVTASLQDRVKSATRRLNPGEKHAKTSMFESMLYTNASGVVVALALAARTGQLSSGVAFCSRHPEATRVVMNYALASVVGQLFIYFTITEFDPLVLSGVTTTRKIFSTVYSVLRDPDPKNALTRTQWTGCGVVFAALGYDVLEKFVKGGGKKKIGGGGDGEAPRRSARKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRP8</accession>
    <name>C1MRP8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_5034</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058545.1">
        <property type="nucleotide sequence ID" value="XM_003058499.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRP8"/>
    <dbReference type="STRING" id="564608.C1MRP8"/>
    <dbReference type="GeneID" id="9684352"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5034"/>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PEVMFFD"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023">
        <property type="entry name" value="PROTEIN TRIGALACTOSYLDIACYLGLYCEROL 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF3">
        <property type="entry name" value="PROTEIN TRIGALACTOSYLDIACYLGLYCEROL 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="268" mass="29059" checksum="09652A159BC84414" modified="2009-05-26" version="1" fragment="single">EVLIELKNVKKKFGKKVVLDGASFKIRRGEAVGIIGSSGTGKSTILRIMAGLLAPDEGEVMIRGRPRAGLLSDEKNPNLKVGMVFQSAALFDSLTVGENVGFKLYEHSDLPEEDIKKLIDESLNQVGLAGVQDRYPAQLSGGMKKRAALARAIIKEDVSDIKDDALEEVVMYDEPTAGLDPVASTVVEDLMRNLHTGTKKKSGSDRGGVASYIVVTHQHSTIRRAVDRLIFLHGGKVVWEGSSEEFDTTDEPIVRQFATGALKGPIVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRT8</accession>
    <name>C1MRT8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_58224</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058567.1">
        <property type="nucleotide sequence ID" value="XM_003058521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRT8"/>
    <dbReference type="STRING" id="564608.C1MRT8"/>
    <dbReference type="GeneID" id="9684006"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58224"/>
    <dbReference type="eggNOG" id="KOG4280">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DFDLWYQ"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056524">
        <property type="entry name" value="KIF6/9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF67">
        <property type="entry name" value="KINESIN MOTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23735">
        <property type="entry name" value="KIF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="4"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="751"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="581"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="644"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="751"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="91"/>
            <end position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="808" mass="87913" checksum="29F31995E93DED18" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRY9</accession>
    <name>C1MRY9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase delta subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_58281</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058590.1">
        <property type="nucleotide sequence ID" value="XM_003058544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRY9"/>
    <dbReference type="GeneID" id="9684398"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58281"/>
    <dbReference type="OrthoDB" id="514823at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904161">
        <property type="term" value="P:DNA synthesis involved in UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.20">
        <property type="entry name" value="DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019038">
        <property type="entry name" value="POLD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041913">
        <property type="entry name" value="POLD3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598:SF13">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09507">
        <property type="entry name" value="CDC27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="124" mass="13171" checksum="19F6E19282D95A8C" modified="2009-05-26" version="1">MPAMSADEILAAIDATVNDDDAVVTFKYVSRKFAIDATTAKRILFAHHAKKGGLAVYCVTGWVGAVGDASRTRVVKLARGADELERVRGGMTEVVSAHVYGVAKKVRSLHCSPYDPVGVVNANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSF4</accession>
    <name>C1MSF4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_47424</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058669.1">
        <property type="nucleotide sequence ID" value="XM_003058623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSF4"/>
    <dbReference type="GeneID" id="9684484"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47424"/>
    <dbReference type="eggNOG" id="ENOG502T0JA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PWRTTNQ"/>
    <dbReference type="OrthoDB" id="564197at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="171" mass="18134" checksum="1CCF26482D4ADCB5" modified="2009-05-26" version="1">MGKSDGYDKNAPCPLGTGTRLITVGGELVAVAHRIKPTGYKAPNAYGNRVAFDGTTTSGSEQAKVRVVGSGEGPKKKLMPYHPLASRNRPKSQTDNATSGRFTMPKGSVEAYRNASQVNLTDGHPDSGRAGSWRTTNQEYSDKSATTGVVGLANQGIFAEAAILTHKKQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT86</accession>
    <name>C1MT86_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57973</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058445.1">
        <property type="nucleotide sequence ID" value="XM_003058399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT86"/>
    <dbReference type="GeneID" id="9683883"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57973"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="315"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="458"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="166"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="458"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="476"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="496" mass="53013" checksum="13241F0E6460C917" modified="2009-05-26" version="1">MLASPSVARGPADVLAHAEMVSLRVAIARQIATSRLSVAQGETGKLVAAAVAASASALLARSPSASPSASPSASPSASPSASPPSANKTANKRKRGTPQRTPASSPLDAAAPSPPAAKTTQDAAAQTSSPEEAAKETIRDEWQRLYALAMKHGGKLDIGRTRHDAIAVLQDEARVARAAAKNAREALETFTRERREHRERGVVDRERFERASSSDSLVFDLFPYPFKWSPPEVSADATLAALEEAATRAESDANAGDAALRCLVEAINHEARAELELTWRAECARQKDIAARVIREIQCFGMPVTGLSAKLVGAATPPAPPVNVEIDDAEDDDDDDDGADAAEKRDWQNEDTQPEDDVEKSPAPRPEGNGASATDAPELARSDTDADAEESDEDDDVPIAKLLMKTDPRPTRRCVVDATPRRAASEPPPLMCETCGAGPFKKQHGLNLHKTRWCVKEKDADETRAREEAPPPPPVKRGRGRPKGSKNKNKFLGELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT87</accession>
    <name>C1MT87_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lon protease homolog, mitochondrial</fullName>
            <ecNumber evidence="10">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MICPUCDRAFT_33463</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer or homoheptamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 11 14 15">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="10"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058821.1">
        <property type="nucleotide sequence ID" value="XM_003058775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT87"/>
    <dbReference type="STRING" id="564608.C1MT87"/>
    <dbReference type="GeneID" id="9683884"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33463"/>
    <dbReference type="eggNOG" id="KOG2004">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WLTNIPW"/>
    <dbReference type="OrthoDB" id="2411602at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070407">
        <property type="term" value="P:oxidation-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000021">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5270:FF:000001">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1480:FF:000002">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000015">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03120">
        <property type="entry name" value="lonm_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027503">
        <property type="entry name" value="Lonm_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="LON PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718:SF2">
        <property type="entry name" value="LON PROTEASE HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 10 11" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="18">
        <location>
            <begin position="13"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="17">
        <location>
            <begin position="663"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="602"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 12 14">
        <location>
            <position position="765"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 12 14">
        <location>
            <position position="808"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <begin position="384"/>
            <end position="391"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH57276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="865" mass="94473" checksum="D88829DFBDE484A0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTB9</accession>
    <name>C1MTB9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58013</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058838.1">
        <property type="nucleotide sequence ID" value="XM_003058792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTB9"/>
    <dbReference type="GeneID" id="9683900"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58013"/>
    <dbReference type="OMA" id="CETTLAR"/>
    <dbReference type="OrthoDB" id="10649255at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021852">
        <property type="entry name" value="DUF3456"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11938">
        <property type="entry name" value="DUF3456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912077" evidence="2">
        <location>
            <begin position="26"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3456" evidence="3">
        <location>
            <begin position="128"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="178" mass="19495" checksum="18BB0574D473A2D3" modified="2009-05-26" version="1">MARSPLLSLPLVLVLLLAAAATARADTEYLRDETRRIDDAVPVTCAACASAVTHIERALRRIDQTTFSSEGDAEATNARNAARRRRSLTHGRSETKIRDALGGACAFLRASEEREDEEKRAAMTRAGFDIAGACETIVETHEEDIEEHVFADGVDGLKDLVCVRLTRACPRLSTRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTC4</accession>
    <name>C1MTC4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58019</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058840.1">
        <property type="nucleotide sequence ID" value="XM_003058794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTC4"/>
    <dbReference type="GeneID" id="9683903"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58019"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="107" mass="12211" checksum="1192EE807540FD52" modified="2009-05-26" version="1">MSYEDAHAIIRRSRPQANPYQVSWDIARSRLLAERLEDIYLYTQVDGGGNSIDQKGDWIKRDVEAAEIGVIRQIFERGVEADLGLVSALCEMGCPRAEEEKKEEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTE6</accession>
    <name>C1MTE6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_39766</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058851.1">
        <property type="nucleotide sequence ID" value="XM_003058805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTE6"/>
    <dbReference type="STRING" id="564608.C1MTE6"/>
    <dbReference type="GeneID" id="9683914"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39766"/>
    <dbReference type="OMA" id="CASFACK"/>
    <dbReference type="OrthoDB" id="2017825at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35097">
        <property type="entry name" value="GDSL ESTERASE/LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35097:SF1">
        <property type="entry name" value="GDSL ESTERASE_LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="374" mass="37936" checksum="EEA40F9CB9B8EBCB" modified="2009-05-26" version="1">MAPPAKNAHAPATSTTDDVQTLRRLTREAFGEITSLRDRLGDLERSVATDRASRVTDAARVDARVTMGGVALGDHRAAAAADVDVAPRAVTTIDAPLPGGDSLVVRLASSSSSSSSSDADPTTVALEKVMYRHRIGSRGWLRISPIGGEGQDAAATLNPLSKGGALTSFGARGPSTLSRCEGAAACASYDFGDGLFGVSGGVFDRDGVEGDDGDSGSENGESGGGKTKTKTRTRRALLQATARPGTRAAVSLAAAASSPSPSPSSSSFELGVNGLFAVGDETLVAAWASSGGGDWGVAATRPPGEDGGSPGWGVAFGVADEGSDRAKSDLRCEAFARLGGESRRVTPGVVARRDGVTGKWCASFACKVDLLYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTG8</accession>
    <name>C1MTG8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58064</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058861.1">
        <property type="nucleotide sequence ID" value="XM_003058815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTG8"/>
    <dbReference type="GeneID" id="9683926"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58064"/>
    <dbReference type="OMA" id="IANGYEW"/>
    <dbReference type="OrthoDB" id="18529at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040922">
        <property type="entry name" value="Ribosomal_mL59_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36781">
        <property type="entry name" value="OS05G0114600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36781:SF1">
        <property type="entry name" value="OS05G0114600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18126">
        <property type="entry name" value="Mitoc_mL59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL59" evidence="2">
        <location>
            <begin position="25"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="142" mass="16209" checksum="0C062C24206EC3CA" modified="2009-05-26" version="1">MTMRYMFMKNIAKLEAALASMPGAAQPTLVEGKWRAPAMSRRKVAELRKAAIAMGKEWPWDVANKNPEYKPPKGHKHERDQGLREAKIEAALKKQPALIEAHKKHRREVRAGKDVTAFDQILMTTKEKILKSRQNPANQKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTL2</accession>
    <name>C1MTL2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_58112</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058512.1">
        <property type="nucleotide sequence ID" value="XM_003058466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTL2"/>
    <dbReference type="STRING" id="564608.C1MTL2"/>
    <dbReference type="GeneID" id="9683951"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58112"/>
    <dbReference type="eggNOG" id="KOG2248">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YPIDYSF"/>
    <dbReference type="OrthoDB" id="16516at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF115">
        <property type="entry name" value="FI18136P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="8">
        <location>
            <begin position="479"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="443"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="514"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="567"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="581"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="605" mass="65500" checksum="53A57CAB4D6E21C0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTL7</accession>
    <name>C1MTL7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_39810</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058515.1">
        <property type="nucleotide sequence ID" value="XM_003058469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTL7"/>
    <dbReference type="GeneID" id="9683954"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39810"/>
    <dbReference type="eggNOG" id="KOG2494">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YPINGNG"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054429">
        <property type="entry name" value="Znf-CCCH_Muscleblind-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12675">
        <property type="entry name" value="MUSCLEBLIND-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12675:SF6">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22628">
        <property type="entry name" value="zf-CCCH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="203"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="247"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="474" mass="47287" checksum="2C2B8F24F1B5BBFD" modified="2009-05-26" version="1">MTAVESVVAAPAPPMAQAVVGRPEVCRDFLKGACFRDNCRYAHSSVDGSQPAVQSNQPICRDFQNGRCFRASCRFYHGSTTDLAANQAANAFAGGAAALAALGAGGFGGFNALQRAVSVPVNGASFANGFGDAAAGSRHSFDGSSGFNINAVGFDPATAAAAMLQSQQQAAAAAAMLFRASQNGAGGANPLAALLAAQAQAGPGGLNGSPTGGLNPDGSPSRHGVDANNGAINGISPDAMATLLAMQQQQLQLQRPRRGSPPRAPSTSPPRGPLPPSDQPAPAPAPAGMLSRSLMFSEQYPEERNGGLGRRHSVDVNGRVGRANPYVSELDAVSSAFNTIDLGLGNSTSVGKSPLGPGGANGVVGGGSPNGFGAANGSSSLWGGFDGGASPLGGASRRASLDVRATPASSRLSLDGGLWEDKSGILSSPKRSIDGRSNGVNIAAPSSLSNGSGIVGSLGAESAEAKRDSTYSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTP1</accession>
    <name>C1MTP1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_4527</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059056.1">
        <property type="nucleotide sequence ID" value="XM_003059010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTP1"/>
    <dbReference type="STRING" id="564608.C1MTP1"/>
    <dbReference type="GeneID" id="9685089"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4527"/>
    <dbReference type="eggNOG" id="KOG2726">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GEEEHEF"/>
    <dbReference type="OrthoDB" id="2019491at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.410">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43116:SF3">
        <property type="entry name" value="CLASS I PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43116">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="2">
        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="337" mass="36863" checksum="7F5C60995EBD7EDF" modified="2009-05-26" version="1" fragment="single">LDPPSLRAMLADLDKRASEATLWDDPKNAKAVMEQLADVREQLELAAAFEDKLGDARTALEMIADDPSSDVVPELASEISDAIASLEAALETWETRRLLVGTYDALGATVFINAGFGGFDAHEWAERLESCYVAWARRRGFAVRVEARTPGEEVGLRSVTLEIDGRFAYGYLASEKGAHRMVRIGGVAGQTPRGRHSNFVAVDVAPTLEEKARSIHWSPYDRVRVITTMRSGGAGGQNVNKVETAVRMKHLPTGIVVRCEEERSQAMNRAKAIARLKAKLAAVAEERRLADVAAVRGDVVRAERGQQIRNYVLHPYKLVKDVRTGVETSDVDGVLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUA1</accession>
    <name>C1MUA1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58725</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059160.1">
        <property type="nucleotide sequence ID" value="XM_003059114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUA1"/>
    <dbReference type="STRING" id="564608.C1MUA1"/>
    <dbReference type="GeneID" id="9684600"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58725"/>
    <dbReference type="eggNOG" id="KOG1695">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DHIEPEY"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="19"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="250" mass="27262" checksum="285B118DAB2B1390" modified="2009-05-26" version="1">MAFSADDSTPIVVADDFPSDARLTYFGLPALAEPVRALFVLSGKPWTDHRIKFPEWKETVKPKTKWGQIPVMTIPGDENEMTQSKAMHRLLACKLSVGGAGATPLYPAGTMQAYRIDEMIDTFEDARMKIVPTFAIAGQAEKEAARAALFVEGGAVHELLLKVEKHCGEFGRIVPTTDGSFTAADAWAHFFVCMHRSGSFDGIPADVVDAKTFPKLNAVVDAWGAIPALKKYYEGMVETGDARYKAFAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUG9</accession>
    <name>C1MUG9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58802</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059492.1">
        <property type="nucleotide sequence ID" value="XM_003059446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUG9"/>
    <dbReference type="GeneID" id="9684636"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58802"/>
    <dbReference type="OMA" id="ESAWTHE"/>
    <dbReference type="OrthoDB" id="498669at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="38361" checksum="FA90191E37261A0F" modified="2009-05-26" version="1">MSASCVSNVRAALAASAATSGRASSAAPAAPRFDRVGAREIRRRRNSNSSHSSSTRVAKNPNYVPDPKRFDMEPNTPRTREEEEYQEGFRQDREWMRYDPDAVPEHAPAPWQVNTARLLDFENNPGAWPPWVTRECEKQGIDVHLHDEPEPEYIPYEETPGLYNRFDDMALQYRERVKAERAAATAKRAEEIRRTSWMSMEGDVRLKDIPSCDESAWTHEKIEELINFPPDVAARMEAHSVLRYDPRWPCDNTWIPPPEPDTWEFLKEIGRGSEDPLEDEALGEKLAMRNGITQRYEVELEAEEFLARSSEAQLQRAIDIGEDDDEDEEEEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVG2</accession>
    <name>C1MVG2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59367</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060033.1">
        <property type="nucleotide sequence ID" value="XM_003059987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVG2"/>
    <dbReference type="STRING" id="564608.C1MVG2"/>
    <dbReference type="GeneID" id="9685185"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59367"/>
    <dbReference type="eggNOG" id="ENOG502QQBA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PWWLVAG"/>
    <dbReference type="OrthoDB" id="498072at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF261">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="265"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="720" mass="75788" checksum="17EE7D9DABF0868A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVN4</accession>
    <name>C1MVN4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_40566</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060068.1">
        <property type="nucleotide sequence ID" value="XM_003060022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVN4"/>
    <dbReference type="GeneID" id="9685222"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40566"/>
    <dbReference type="eggNOG" id="ENOG502QQ6J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RRRWAND"/>
    <dbReference type="OrthoDB" id="75169at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025952">
        <property type="entry name" value="R3H-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039629">
        <property type="entry name" value="R3HDM4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32019">
        <property type="entry name" value="R3H DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32019:SF2">
        <property type="entry name" value="R3H DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13902">
        <property type="entry name" value="R3H-assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H-associated N-terminal" evidence="2">
        <location>
            <begin position="248"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="461"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="521" mass="55862" checksum="9A639EDC290D62EA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVT4</accession>
    <name>C1MVT4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59497</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059804.1">
        <property type="nucleotide sequence ID" value="XM_003059758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVT4"/>
    <dbReference type="GeneID" id="9685243"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59497"/>
    <dbReference type="OMA" id="SRWCVEV"/>
    <dbReference type="OrthoDB" id="46025at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="306" mass="32758" checksum="5E1F550B75A827B5" modified="2009-05-26" version="1">MAPNFNSPKQALEQGVCGQHGWSSRYFQDPDTSRWCVEVRWGVGSSQRQVFVSDDESDAASKPGIKKGHAAAATVALEGLTEILRAANVKPSRTIDETFGPRFDATCRVLGGGHGFENGWDALWACAPSVVAVDVEGNQRTPPVLVQVCARVGADTLCVLETPSVAEGLSENLRRLLDDDAIVKVFCDGTSGADKRSLGVRSTCNVLDLEHVATELAGATGVQRGLARILNLAWPDATVRVTKDAAEKSSVKFFAAIERGTRPPLSGLHDIPPDVVRYAAMDAWCTLLAHQGLQLLARREGISIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVT7</accession>
    <name>C1MVT7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_18351</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059806.1">
        <property type="nucleotide sequence ID" value="XM_003059760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVT7"/>
    <dbReference type="STRING" id="564608.C1MVT7"/>
    <dbReference type="GeneID" id="9685245"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18351"/>
    <dbReference type="eggNOG" id="KOG2106">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DIQWFTH"/>
    <dbReference type="OrthoDB" id="47802at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000320">
        <property type="entry name" value="echinoderm microtubule-associated protein-like 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055439">
        <property type="entry name" value="Beta-prop_EML_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005108">
        <property type="entry name" value="HELP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF33">
        <property type="entry name" value="HELP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23409">
        <property type="entry name" value="Beta-prop_EML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03451">
        <property type="entry name" value="HELP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EML-like first beta-propeller" evidence="4">
        <location>
            <begin position="97"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="300"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="EML-like second beta-propeller" evidence="5">
        <location>
            <begin position="398"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="476"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="681" mass="73809" checksum="4DE0DEDDE4DF81E0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWF4</accession>
    <name>C1MWF4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Peptide deformylase</fullName>
            <ecNumber evidence="2 7">3.5.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_6170</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Removes the formyl group from the N-terminal Met of newly synthesized proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 7">
            <text>N-terminal N-formyl-L-methionyl-[peptide] + H2O = N-terminal L-methionyl-[peptide] + formate</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2 7"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059914.1">
        <property type="nucleotide sequence ID" value="XM_003059868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWF4"/>
    <dbReference type="STRING" id="564608.C1MWF4"/>
    <dbReference type="GeneID" id="9685645"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6170"/>
    <dbReference type="eggNOG" id="KOG3137">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PSYEPIG"/>
    <dbReference type="OrthoDB" id="276063at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.45.10:FF:000003">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001159">
        <property type="entry name" value="PRK00150.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PEPTIDE DEFORMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458:SF2">
        <property type="entry name" value="PEPTIDE DEFORMYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH55866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="185" mass="20488" checksum="17335F556BF51941" modified="2009-05-26" version="1" fragment="single">EIVQAGTPCLREIAEEVPLSSIDTAKTQELIQEMLSICRGRGVGLAAPQIGVPYRIFVLEDTEEGMSDVSKKDLEAMDRKPFAAKVVINPVVTPVSNLSAAFFEGCLSVQGYRGLVRRYLEVRVTGYGGDGSPVDFVARGWQARIVQHEMDHLNGVLYVDRMDTRTFRRVDKLDEPLPPAHPEFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWJ1</accession>
    <name>C1MWJ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59788</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060226.1">
        <property type="nucleotide sequence ID" value="XM_003060180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWJ1"/>
    <dbReference type="GeneID" id="9685371"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59788"/>
    <dbReference type="eggNOG" id="ENOG502SW8V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MAFIVRA"/>
    <dbReference type="OrthoDB" id="568267at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="284" mass="30659" checksum="096328792D481590" modified="2009-05-26" version="1">MEPETMDGVVDAAQYPVDAVTADAMTTDVGPKGLGMSLDDLVRESKPAGGGRGGRGHKGEGGRLKVRAVIVKRPAGGGRGFGGRGPAPPRKTVRSMAFIVRASDRSNVRAFVVRSFVRSFVRSFVHDWIDPRRRSVPSHPSIPPTLTRLFSDARSFVPSQPGKIYKRDDGVVVLHMYGKDVLAANNQGEVTLDADGDRGKNTFLGVHDALSRFGFKLSRPNPAAPEEWSVSDGKKFLKRYEDGMVIPAPKPPGPGRMLALLQTEVRAGRRVLSHTGPRTTASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWK5</accession>
    <name>C1MWK5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_47798</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060235.1">
        <property type="nucleotide sequence ID" value="XM_003060189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWK5"/>
    <dbReference type="GeneID" id="9685376"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47798"/>
    <dbReference type="OMA" id="WERTQTE"/>
    <dbReference type="OrthoDB" id="1928614at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14702">
        <property type="entry name" value="bZIP_plant_GBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045314">
        <property type="entry name" value="bZIP_plant_GBF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044827">
        <property type="entry name" value="GBF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45967:SF28">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER (BZIP) TRANSCRIPTION FACTOR FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45967">
        <property type="entry name" value="G-BOX-BINDING FACTOR 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="211"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="116"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="448" mass="44833" checksum="F1875C5CD5396BDF" modified="2009-05-26" version="1">MAPPPPAKKKTRTARGAAAATNDGDAATARPRAAEEKKPSSALQWGRKQTRTTSEADPRPKAARGPSTTANARGGSGANDAGIPGANEQHPSAAITGDSVGFTSLLTLADAGVQLERRSAQKQRRSDKIAASKSNAAAAAAAAAAETAANGFVAQSGRKGSNIATAASRGAASGAAPSSAGAPGSSVVAENPGKKRGRGPNKKEESEEDLEAKRRKRVQANRESARETIRRKHEKYDELSAREEELTGENATLRGDVAEALRRARALAAENDALREKVRAAAAEKGVACPAFGERARVEPPSEFQPESAGVVPVAGVRMLLDGGAAPVAVGGAAAQFPAIAAAGPTNEGRDGGECAGTSVTTAAAAAAAAAATAAAAMRPAAAAAWPNPQMAFGMFTSNGFNMANMPPPHLWNPAAMAAALGGGGWGVPLAQGAATTAATTAAPAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWX8</accession>
    <name>C1MWX8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65330</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059999.1">
        <property type="nucleotide sequence ID" value="XM_003059953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWX8"/>
    <dbReference type="STRING" id="564608.C1MWX8"/>
    <dbReference type="GeneID" id="9685437"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65330"/>
    <dbReference type="eggNOG" id="ENOG502SHJS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="546611at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="523" mass="57267" checksum="0E3DC498A88C4AA9" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX10</accession>
    <name>C1MX10_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_59322</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060015.1">
        <property type="nucleotide sequence ID" value="XM_003059969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX10"/>
    <dbReference type="STRING" id="564608.C1MX10"/>
    <dbReference type="GeneID" id="9685103"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59322"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VPLFIHQ"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19094">
        <property type="entry name" value="AKR_Tas-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="111"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="489" mass="53586" checksum="C77E88E20D7B7E53" modified="2009-05-26" version="1">MHALSTPSRVHGAFKRAPSTRATDERRASTPRPARRTVVASPVVAAGLGSLFPFGGDKPSNAAKGASSSANAGGFSQGAANVGSTNEVAEVVDGMRRKRLGDTDILVSEFALGTQRWGGADFNSPDEKLCHALMDRAVLECGVNLLDTAEQYPIPSDRSRPEGDTERIIGSWMKKDRSRREKLVIATKITGGGNVTKKNIKKDLEGSLRRLGTDYVDVYTLHWPARYTPQSNWGQSLQYHQETEAAPWYRNHASFEEIAEATGELIDEGKLRGWGMCNDNAYGLTASVYAARAIGKYPPCVLQGDFSIINRRSEENGVSEASSPTNENVGFMAYNALAGGVLTGKYLDVPAAVDNARDPKLAEKLLDNPRGRMDDYSWGKTLYRYRSGPAEAATREYAKIAKEAGMSLTELALRWCRDRALVTTTLIGHTSLEQLDETLKYFGKDIRPLPADVNWAIDRVHMRNRLPIFSSDRVGADWEGSGEIGERIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX25</accession>
    <name>C1MX25_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40881</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060324.1">
        <property type="nucleotide sequence ID" value="XM_003060278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX25"/>
    <dbReference type="STRING" id="564608.C1MX25"/>
    <dbReference type="GeneID" id="9686054"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40881"/>
    <dbReference type="OMA" id="SRRIMCE"/>
    <dbReference type="OrthoDB" id="10691748at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="103"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="313"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="400"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="480"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="564"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="610" mass="68126" checksum="4F3E05BC0F71AE97" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX49</accession>
    <name>C1MX49_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Early light induced protein-like 3, chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CBR/ELIP5</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_60028</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060335.1">
        <property type="nucleotide sequence ID" value="XM_003060289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX49"/>
    <dbReference type="STRING" id="564608.C1MX49"/>
    <dbReference type="GeneID" id="9686067"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60028"/>
    <dbReference type="eggNOG" id="ENOG502RZBJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GPELMNG"/>
    <dbReference type="OrthoDB" id="513190at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="18"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="210" mass="21314" checksum="42DDBDDDF3F6F970" modified="2009-05-26" version="1">MSAFTVAARTTVAARATVASSANRRSVRAAAEPEQKSSGGEVFFTDKNGDGQRATPEEYEAAKAAGNTYQASTVTGDLPEWAAGATADSDISLSLGDAFAFAQVPAATNFVASGPELMNGRLAMIGFVAALGCEIATGETVGQQVAQSPVGVAVVTMLIVGGTLISYCSNTKPPAAGPFNQQKELLNGRAAMVGMASLLAFEAVKGVALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY45</accession>
    <name>C1MY45_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60397</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060504.1">
        <property type="nucleotide sequence ID" value="XM_003060458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY45"/>
    <dbReference type="GeneID" id="9685942"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60397"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="105" mass="10304" checksum="972AE0C259E4FD7F" modified="2009-05-26" version="1">MSDVGDDDVGEDAGASGGRRRRLDDGDGDGDDDDGGGASSSTSSDSGSGGAGDERNREEAELLPDFAYTNLTELAMANMSLASGGGGVGGSGFATPEIATSPPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYA5</accession>
    <name>C1MYA5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_59836</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060248.1">
        <property type="nucleotide sequence ID" value="XM_003060202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYA5"/>
    <dbReference type="STRING" id="564608.C1MYA5"/>
    <dbReference type="GeneID" id="9685981"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59836"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="6"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="259"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="297" mass="32898" checksum="466B2C011978C205" modified="2009-05-26" version="1">MPIPKLPDDVAREIFAHVPTVTDRLALASTCTAFNRASKHARSLPRDGGLDFAGCARGGRKPWTHGYKNERSEGVEKLEYLMLHEGVLDLPEEQFKKLVVSTGCVENGRIRILNDDDGAAGVVGPICVYAIGQSYSCEYAYDKMLPWLRKAAALGSTGASYCLAKAYMNGKGVEKNIEKAVEFYREAAKDGDRIHQFELAETLLTWAAVWMEKAAEQGHGTALAETAFNYRWGNGVEQDDVKEIEWQLKLDALPSPIPSSDESQSSDESQSSDESQSEDEEQSEDEEQTNTETDDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYF6</accession>
    <name>C1MYF6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59895</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060565.1">
        <property type="nucleotide sequence ID" value="XM_003060519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYF6"/>
    <dbReference type="STRING" id="564608.C1MYF6"/>
    <dbReference type="GeneID" id="9685721"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59895"/>
    <dbReference type="OrthoDB" id="534245at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47467">
        <property type="entry name" value="OS01G0867200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47467:SF1">
        <property type="entry name" value="WD40 REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="187" mass="19784" checksum="8F9B25E08C198236" modified="2009-05-26" version="1">MERPLVKRTSISNRGDDATFVLDCGLAGGDDGGGGVSLPNARAGEPMILCAGADRGVTVVNETRMRAVARWTNAMKARSILHRSLPFEITGAKFSAASPDHVYVASGLDYELVCGCWTRQAIAGGFSFRGDSRLLGMATSEAGAGKDIVAAWCESGNLIAARVERVGGVRSTHWSPYDRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYZ5</accession>
    <name>C1MYZ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60545</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061125.1">
        <property type="nucleotide sequence ID" value="XM_003061079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYZ5"/>
    <dbReference type="STRING" id="564608.C1MYZ5"/>
    <dbReference type="GeneID" id="9686309"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60545"/>
    <dbReference type="eggNOG" id="KOG2293">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EAHYQRM"/>
    <dbReference type="OrthoDB" id="10262769at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071339">
        <property type="term" value="C:MLL1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044545">
        <property type="term" value="C:NSL complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002151">
        <property type="term" value="F:G-quadruplex RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22687">
        <property type="entry name" value="FHA_MCRS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037912">
        <property type="entry name" value="MCRS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025999">
        <property type="entry name" value="MCRS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13233">
        <property type="entry name" value="MICROSPHERULE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13233:SF0">
        <property type="entry name" value="MICROSPHERULE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13325">
        <property type="entry name" value="MCRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="257"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="354" mass="36895" checksum="5A4D2C1327325902" modified="2009-05-26" version="1">MTDAAAAVASTAAPAPAAAPAANDAAPAPVLGAKLDDFPVGDDFLLREAVEAGAALGAIARGILPFSRPYTREEITARWRALLYDPNVARPAAKRMARYIVDASPKVAPLPVGPDFARAFAARKKKAAAAAAAAEAEAESVPADGGGGDAMAMNGEDGGGNGDDDVDEHLGYIGLDAPPSFAEAEACVLDLPALPAFAQVDADERKRAKTALARALHKIRKLEASAQAATARAATAKGALGVLQGANATFLLTKRETIIGRSTDDQKVDVDLAEEGNASKVSRQQAFIRLRYNGEFVLRNVGRRPVWVNATGVESGHRCALAPHSLIEVGGMRLLFLPNPTLVRKQEPEPVAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ09</accession>
    <name>C1MZ09_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41198</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061132.1">
        <property type="nucleotide sequence ID" value="XM_003061086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ09"/>
    <dbReference type="GeneID" id="9686571"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41198"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="239" mass="25680" checksum="A663B86E6E9EFDDF" modified="2009-05-26" version="1">MVALTEDEDVVADVETETRAREMELELAAAVQAWSAALDADDPNEESDAAFQWLNVARTYLRLTSKEGSAIVRAIDAVNTHRRAVNPHAAYGYVYTLDVLPVLAPLIKNPDDALAKGVRVLVAADFACALASKDEATGSHDHYGDAMTLLAAAPSVTAAPPPPVDPLTNAPVSSRSICARVFPDGKASTSDHARAKIRRASEGLQLCRELGLGGRRRRRRRRVLDPVARGRRGRGGPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ40</accession>
    <name>C1MZ40_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_41218</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060891.1">
        <property type="nucleotide sequence ID" value="XM_003060845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ40"/>
    <dbReference type="STRING" id="564608.C1MZ40"/>
    <dbReference type="GeneID" id="9686588"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41218"/>
    <dbReference type="eggNOG" id="KOG0143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CRLLHYF"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="175"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="331" mass="37068" checksum="F66E5BEF3B7FFCA8" modified="2009-05-26" version="1">MGADAEDDDHVPVVSTELYDADFDAFVKARNARALGAAYEKYGFVILQNHGVPDELISRSLECSKRFFALSSEEKMRYHLPGLGGARGYTAFGVETAKGSAHHDLKEFWHLGRDLPVGHPLERYMPPNVRVREGDFTSATTEVYRALDALGGRVLEALAVHLGQTRDYFADKVNEGNSILRVIHYPALVKEGQDVNEALSKAGHVRAAAHEDINLITLLLGADEGGLELLRRDGKWMEVNPPPGCVTCNIGDMLQRLSNHRLPSTTHRVVNPKPERTAFPRYSMPFFLHPNPDFVIDTLSTCVSEEHPNRYPEPITSDEYLQQRLREIKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ42</accession>
    <name>C1MZ42_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60595</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061150.1">
        <property type="nucleotide sequence ID" value="XM_003061104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ42"/>
    <dbReference type="GeneID" id="9686589"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60595"/>
    <dbReference type="OMA" id="ASACSEW"/>
    <dbReference type="OrthoDB" id="10615897at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912264" evidence="2">
        <location>
            <begin position="25"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="235" mass="25862" checksum="EC75C0C3D48F73B4" modified="2009-05-26" version="1">MHRSTRAIALCLVVVLACAPAAHARKQRGDEKERERDELRDQEARVGSTERRGAVVETDHPSPTPQGKWWGYWGYWGYWGSTYKWNYAWSYPYYCGALRGASSPSSLSSHTSFCFFFLRSTLTRSSAREDYYGYGGWYRAADIISDANATTSELAEARAISRQINAARATRRAALGCVDWLGVDEEKISSAPKELAVVDDACCYPSGCALAESSGCVADGAACCVPDSTREEGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZH1</accession>
    <name>C1MZH1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_19777</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061218.1">
        <property type="nucleotide sequence ID" value="XM_003061172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZH1"/>
    <dbReference type="STRING" id="564608.C1MZH1"/>
    <dbReference type="GeneID" id="9686657"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19777"/>
    <dbReference type="eggNOG" id="KOG0593">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MEMFRQN"/>
    <dbReference type="OrthoDB" id="548217at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07833">
        <property type="entry name" value="STKc_CDKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:001093">
        <property type="entry name" value="Cyclin-dependent kinase-like 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF111">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE-LIKE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="4"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="298" mass="33604" checksum="F8636CDF21B467C5" modified="2009-05-26" version="1" fragment="single">MNKYEVVGVVGEGAYGVVLKCRNKETGDVVAVKKFKARRGDDDEAVKKTTLREVKVLRSLEHENVVSLKEAFRRKGKLYLVFEYVEKNLLEVLEERPGGLSPDTTRRYVWQLARAVAHCHRLGIVHRDIKPENLLVNPRSDRANALKLCDFGFARPLRAKAGRAASPLTDYVATRWYRAPELLLGSTSYGFEVDAWAIGCIMGELIDGQPLFPGESDVDQLYVIQKAMGGLTKSQTSDFLRNKRFAGLKFPDMSTPDGIERRYAGKCSNKGMAFMKATLAMDPKERLTWHGMLTHPYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZK7</accession>
    <name>C1MZK7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60765</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061236.1">
        <property type="nucleotide sequence ID" value="XM_003061190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZK7"/>
    <dbReference type="STRING" id="564608.C1MZK7"/>
    <dbReference type="GeneID" id="9686410"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60765"/>
    <dbReference type="eggNOG" id="ENOG502QRPB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SWTYRSD"/>
    <dbReference type="OrthoDB" id="10046650at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35313">
        <property type="entry name" value="NO EXINE FORMATION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35313:SF1">
        <property type="entry name" value="NO EXINE FORMATION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="472"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="526"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="618"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="650"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="737"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="768"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="798"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="824"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="880"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="979"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1082"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="908"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="912"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1163" mass="118615" checksum="256E627B9B267E3F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZL3</accession>
    <name>C1MZL3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60771</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060973.1">
        <property type="nucleotide sequence ID" value="XM_003060927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZL3"/>
    <dbReference type="GeneID" id="9686679"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60771"/>
    <dbReference type="eggNOG" id="ENOG502SAAX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3863715at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00719">
        <property type="entry name" value="GIY-YIG_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="2">
        <location>
            <begin position="26"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="241" mass="27794" checksum="47373B005CD1337A" modified="2009-05-26" version="1">MLAPSLEAAARPPRSTPADAAGTETATQHIYVLKLEDDCFYVGKTTDVRGRLEKHRRGCNTWAWTAKHKPIPGDDAIYFVETMTEPTAEDAITERMMCEYGIDKVRGGTFSKPNLPEHQAKTLKDKWCTWTDSCFVCREAGHKSINCRRRKEMVRRDLEEAREREEHARAEDELLFSFDNLSVSHTSHPKNSGKKWTEEEKEQLAREKREGKTNEEIAGIHERSVNAIYMQWNKQKPRDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZR4</accession>
    <name>C1MZR4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41366</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061265.1">
        <property type="nucleotide sequence ID" value="XM_003061219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZR4"/>
    <dbReference type="GeneID" id="9686438"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41366"/>
    <dbReference type="OMA" id="WNESAFT"/>
    <dbReference type="OrthoDB" id="10413706at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="20129" checksum="4BCE209FA29140D8" modified="2009-05-26" version="1">MSDSTRDNVYMSLSFKFNALMVYASLVVAAFVDAYTDNTYSFEAQMDIMTLVFQICAMLLTVVALYNVMSETTYLKRMYYGKIVEEFSPTFFALATYFVFMLISRVYKVSLIFAGYPQLAMWESAAGYTTLYSLMKVFNVLYYCTVVWAMQKLFASPELFKARETAFQPVRPNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N015</accession>
    <name>C1N015_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60933</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061316.1">
        <property type="nucleotide sequence ID" value="XM_003061270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N015"/>
    <dbReference type="GeneID" id="9686488"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60933"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="36794" checksum="E52375F1095B7779" modified="2009-05-26" version="1">MQEPEVVRRGLPDAIVLALPYLVGAISLRFERDGFIHVTPRHLKILFEWEREVARCTKEEGEKFLTRFDHLSAAGGAAGGAEVKQAWEAWEAGLWEAEKRGDGKMTAARESFPSIDHGRVVAACWAEYAKTLREAAMRGDAKQLLTYDANETLGDAYPGFHTRVGGRVDLDVTSALKTVLPFGPEDAPWVPLVKHLLGVDKVRSIKSVDGRYGFGCVVSAPGDLDQNWHQDGDTTRDPNAQTNTVIVFTQSLPVLDDMGKLQVIPGSHRVRNVPGHELPPELEAKTENLREWPSMRTSFSPSVSPDDGEPGDVLVMDYRRVLYTGPHTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N086</accession>
    <name>C1N086_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_28495</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0235 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH55003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061353.1">
        <property type="nucleotide sequence ID" value="XM_003061307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N086"/>
    <dbReference type="STRING" id="564608.C1N086"/>
    <dbReference type="GeneID" id="9686522"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_28495"/>
    <dbReference type="eggNOG" id="KOG3276">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4397">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CSGCELF"/>
    <dbReference type="OrthoDB" id="418131at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="entry name" value="YggU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057965">
        <property type="entry name" value="STEEP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053323">
        <property type="entry name" value="UPF0235"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47525">
        <property type="entry name" value="OS07G0295200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47525:SF1">
        <property type="entry name" value="OS07G0295200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25809">
        <property type="entry name" value="STEEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="YggU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STEEP1" evidence="2">
        <location>
            <begin position="17"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="224" mass="24484" checksum="0901068292D81DB9" modified="2009-05-26" version="1" fragment="single">MPKRSTQTYSSEDAPESDDAKIVVYYCKYSGDPVLITDAVLGQLPKRKTDGARVLDTTKHVVRLKATPEVKAVLVKRDGGKLEKQYRYRCGELPVCYKSEPEGKYLYVMDGAVSAFNFGAGGGAGEAGETPVPPCIQPKTPGTVQIALEIEDRKKWRAITKITADEVGVAVNAKCAVANDEIVEFLGKTLHLRLPQMSLLAGWSARSKLLVVQGLTPQQVYDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N159</accession>
    <name>C1N159_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_44722</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061512.1">
        <property type="nucleotide sequence ID" value="XM_003061466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N159"/>
    <dbReference type="STRING" id="564608.C1N159"/>
    <dbReference type="GeneID" id="9687193"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44722"/>
    <dbReference type="eggNOG" id="KOG2532">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FYKHPKD"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17380">
        <property type="entry name" value="MFS_SLC17A9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000058">
        <property type="entry name" value="ascorbate transporter, chloroplastic isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044777">
        <property type="entry name" value="SLC17A9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF399">
        <property type="entry name" value="FI19708P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="393" mass="40668" checksum="281B4C70E887B06A" modified="2009-05-26" version="1">MSVVGLPLANLNGWSPSVVGLVQSSFLWGYALTPLVGGVLADKIGGDAVLMYGITLWSLATIATPFAATSASLPLLLLTRAVMGLGEGVALPCMNNLVARWAPTRERSRAVSVCMGGFQSGSMVGLLAAPHMLRVGGVHGPFVAFGALGLTWAGRVSDAELSLIEDGGAVTEEKQWQQSEEGGTNGKGGGKVPFRLLLSKMPTWACVVANFVNNWGYFILLAWMPLYFREVVGLDLASASYFSALPWATMAVVGVCAGALADWMIARGVSTTTTRKLIQGVGFLGPAAALVALTFTSTPAQALTALTVAIGCTAFTQAGFLVNFQEIGPRYVGALHGMANTAGSAAGIVGTYGAGVILGKTGSWSAVLLITAGVYAFGAVFWLAFSTGERVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1L7</accession>
    <name>C1N1L7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_51455</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S41B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061579.1">
        <property type="nucleotide sequence ID" value="XM_003061533.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9687019"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51455"/>
    <dbReference type="eggNOG" id="ENOG502RZ06">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43744at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07562">
        <property type="entry name" value="Peptidase_S41_TRI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.44">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.60">
        <property type="entry name" value="Tricorn protease N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028204">
        <property type="entry name" value="Tricorn_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029414">
        <property type="entry name" value="Tricorn_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012393">
        <property type="entry name" value="Tricorn_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="WD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43253">
        <property type="entry name" value="TRICORN PROTEASE HOMOLOG 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43253:SF1">
        <property type="entry name" value="TRICORN PROTEASE HOMOLOG 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14685">
        <property type="entry name" value="PDZ_Tricorn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14684">
        <property type="entry name" value="Tricorn_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26549">
        <property type="entry name" value="Tricorn_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69304">
        <property type="entry name" value="Tricorn protease N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Tricorn protease C1" evidence="9">
        <location>
            <begin position="1265"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="domain" description="Tricorn protease PDZ" evidence="10">
        <location>
            <begin position="1380"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="domain" description="Tail specific protease" evidence="8">
        <location>
            <begin position="1604"/>
            <end position="1732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="146"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="865"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1506"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="892"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1506"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1554"/>
            <end position="1563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH54209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1741" mass="181380" checksum="DF9BF43DF5AA7079" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2A0</accession>
    <name>C1N2A0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_70156</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062053.1">
        <property type="nucleotide sequence ID" value="XM_003062007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2A0"/>
    <dbReference type="GeneID" id="9687493"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70156"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="283" mass="30312" checksum="2018012BB9918193" modified="2009-05-26" version="1">MGLAHSLSDVVDGPRLSLSLSIFLVFFWFFRRPLFRSDAHLIPQEVGRNITGAAYRFKEVRGLFRAAAEAMQAEGELTFLPEMVAPNAKKINPNDRSPFTGGRGGGGSASGSSKTKTRKAERKESRMKAAARGQGKGNQNLLGKRQRETPGEKREREREENAREDFFIARLKNEGIGSPARKRQKKNAASGMVNGGKGKGKTKSKNGVEATAAYGNSKNGNSKSKQKNRTSPGGGGKGGGGRPDVKPKSAARRNAKKKTKKRKGASAAANGSGKRGRKGWGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2D6</accession>
    <name>C1N2D6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_51489</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061856.1">
        <property type="nucleotide sequence ID" value="XM_003061810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2D6"/>
    <dbReference type="STRING" id="564608.C1N2D6"/>
    <dbReference type="GeneID" id="9687507"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51489"/>
    <dbReference type="eggNOG" id="KOG0190">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RALMFIM"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912243" description="Thioredoxin domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="20"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="305" mass="32632" checksum="27AF5F93B97AC646" modified="2009-05-26" version="1">MASPVRALLPVLLLALLGAARVRADADAAAEPSSSSSSSIEAESLTAAELDAAMFSDDATTLLVELYAPWCGHCKRFAPTYDAIAAALASSDASANKIRVIKVDATRDDDARDLAAKVMGVKGFPTFRLVHDRALYEYNAKQRNAELLIEFARGGFKARGTPKRSLTRDPVTGKTALVPKPFLERNLDFVREEVAKVTRDVTTVAGKFPAAMVVIVSLTAATTAMAFVLTEMIAERVGLSARGAGPTETESDRDARRAWEIEKLERAARGTKATGAANERRRSVDREGGSGRSPPVSPRSVKKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2F8</accession>
    <name>C1N2F8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51512</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061864.1">
        <property type="nucleotide sequence ID" value="XM_003061818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2F8"/>
    <dbReference type="GeneID" id="9687521"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51512"/>
    <dbReference type="OrthoDB" id="205639at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="698" mass="74865" checksum="50EABAE318DBF8E4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3G5</accession>
    <name>C1N3G5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_52163</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062373.1">
        <property type="nucleotide sequence ID" value="XM_003062327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3G5"/>
    <dbReference type="STRING" id="564608.C1N3G5"/>
    <dbReference type="GeneID" id="9687813"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52163"/>
    <dbReference type="eggNOG" id="ENOG502S35P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10052237at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049177">
        <property type="entry name" value="MgtC_SapB_SrpB_YhiD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778:SF1">
        <property type="entry name" value="MAGNESIUM TRANSPORTER YHID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PROTEIN MGTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="MgtC/SapB/SrpB/YhiD N-terminal" evidence="7">
        <location>
            <begin position="20"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="355" mass="37456" checksum="87D4FEF88B14E98C" modified="2009-05-26" version="1">MLMSEVLGEAAGTFLLKQCVAALLGMLIGLQREFGYLVGMWWSKNKLAESPVRRAGLRTHMLVALGSCLFSEASWSLYSVPVPTQLVGDDGTNGRARAPYVSGTFNYDSSRVAAQIVSGIGFLGAGTIWKASDQVFGLTTAASLWTTAAVGMHVGGVHEGKDDTYFLAPCFATLLVVVTLQILIMFELWVHRWMRSYTMRYQAARATLAVAPHASVENAVHDVVDEVEKKVGQVVALGAVIESGVSGPCAAGGGGAAGFSSASSAGGIPASIAEDDRTRRLEISLTVVVPPFSSGVVLLDRLAMIDGVYKASIAEQRSNVVSFVDAGGARVRRGRGMERPFIASGDGCDDDGEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N443</accession>
    <name>C1N443_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52403</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062729.1">
        <property type="nucleotide sequence ID" value="XM_003062683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N443"/>
    <dbReference type="STRING" id="564608.C1N443"/>
    <dbReference type="GeneID" id="9688169"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52403"/>
    <dbReference type="eggNOG" id="KOG2785">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19329at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="647" mass="69427" checksum="1CAD8C66D698955D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N450</accession>
    <name>C1N450_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52411</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062731.1">
        <property type="nucleotide sequence ID" value="XM_003062685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N450"/>
    <dbReference type="GeneID" id="9687925"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52411"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="521" mass="56631" checksum="FBACAD0E5E7321D5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1N497</accession>
    <name>C1N497_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_52469</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062753.1">
        <property type="nucleotide sequence ID" value="XM_003062707.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N497"/>
    <dbReference type="GeneID" id="9688400"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52469"/>
    <dbReference type="eggNOG" id="KOG1080">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WLERECP"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045606">
        <property type="entry name" value="ATXR3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46655">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE ATXR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46655:SF1">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE ATXR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19633">
        <property type="entry name" value="SDG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="8">
        <location>
            <begin position="270"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="1072"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="833"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1023"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1209"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1360"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="835"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1023"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1364"/>
            <end position="1375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1401" mass="145209" checksum="B7EBF645401A0EDF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4F9</accession>
    <name>C1N4F9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52542</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062782.1">
        <property type="nucleotide sequence ID" value="XM_003062736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4F9"/>
    <dbReference type="GeneID" id="9688433"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52542"/>
    <dbReference type="OrthoDB" id="10614750at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="123" mass="14627" checksum="6DC9294F8421DADF" modified="2009-05-26" version="1">MERSGNEYEAPREEREMEFAARKDTQEDRVNDGKRYSGLLTKEDYDARKRGFAERIRAERDPEAYAKEKLDAAVAREVAIERAAADARRERERIRREKLRAELEVRSIHWFPYDRVRVVDADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>C1N507</accession>
    <name>C1N507_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine/threonine-protein kinase TOR</fullName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">TOR</name>
        <name evidence="16" type="ORF">MICPUCDRAFT_21889</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063087.1">
        <property type="nucleotide sequence ID" value="XM_003063041.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N507"/>
    <dbReference type="GeneID" id="9688326"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21889"/>
    <dbReference type="eggNOG" id="KOG0891">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MRQHSAK"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016242">
        <property type="term" value="P:negative regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05169">
        <property type="entry name" value="PIKKc_TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000029">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.150:FF:000001">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000006">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.150">
        <property type="entry name" value="FKBP12-rapamycin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009076">
        <property type="entry name" value="FRB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036738">
        <property type="entry name" value="FRB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024585">
        <property type="entry name" value="mTOR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026683">
        <property type="entry name" value="TOR_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08771">
        <property type="entry name" value="FRB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11865">
        <property type="entry name" value="mTOR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01346">
        <property type="entry name" value="DUF3385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01345">
        <property type="entry name" value="Rapamycin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47212">
        <property type="entry name" value="FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="14">
        <location>
            <begin position="1269"/>
            <end position="1858"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="13">
        <location>
            <begin position="2035"/>
            <end position="2350"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="15">
        <location>
            <begin position="2422"/>
            <end position="2454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1115"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="2397"/>
            <end position="2423"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1338"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH53026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2454" mass="269911" checksum="A179728B917108DC" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1N580</accession>
    <name>C1N580_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrogen regulatory protein PII, potentially chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GLB1-PII</name>
        <name evidence="2" type="ORF">MICPUCDRAFT_49733</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the P(II) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062922.1">
        <property type="nucleotide sequence ID" value="XM_003062876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N580"/>
    <dbReference type="SMR" id="C1N580"/>
    <dbReference type="STRING" id="564608.C1N580"/>
    <dbReference type="GeneID" id="9688564"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49733"/>
    <dbReference type="eggNOG" id="ENOG502RUKA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MTGGRTD"/>
    <dbReference type="OrthoDB" id="2016645at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="NITROGEN REGULATORY PROTEIN P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115:SF11">
        <property type="entry name" value="NITROGEN REGULATORY PROTEIN P-II HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="191" mass="19681" checksum="8FA11FAFE5EEF4D7" modified="2009-05-26" version="1">MASAALLAAPAASASRRALAVAARRSPRRIALAFAVQGAGASNGARERATLAPVSTDPNVAFYQVKALVRPWRLDGVVHALNEAGILGLTTYAVQGAGAQVGSSERYKGTEFTGGAATDALVEKVCIEVVVETAQAQDVVDTIVNAAQTGEIGDGKIFLLPVHDVVRIRTGEVGENAERMAGGRKDMKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5Z4</accession>
    <name>C1N5Z4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LI818R</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_53102</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063244.1">
        <property type="nucleotide sequence ID" value="XM_003063198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5Z4"/>
    <dbReference type="STRING" id="564608.C1N5Z4"/>
    <dbReference type="GeneID" id="9688684"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53102"/>
    <dbReference type="eggNOG" id="ENOG502RXY6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DYTPGDY"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="253" mass="27001" checksum="DCBF96743D555B35" modified="2009-05-26" version="1">MAAICAMNIVAKAATTGKVKTSQSKTYKDLGAAVKAGLVRGTAPFPEGIDAFGFFNGISEGEAKRYADVEITHARICMLASLGFLVGEQVEGSSFLFDSNVTGPAINHFQQVPGLFWGLLGAAIFTVEASRVQYAWQNPFDAEKLFLLKDDYTPGDYNFDPLKLSKGKDEAWLNDMKLKEINNGRVAMVAISGMVAQELVNGLNLIPADEVLEMGKEGALKAMEAQCTGAPDEAACAKAFEAAERAAVFASTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N684</accession>
    <name>C1N684_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53190</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063490.1">
        <property type="nucleotide sequence ID" value="XM_003063444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N684"/>
    <dbReference type="STRING" id="564608.C1N684"/>
    <dbReference type="GeneID" id="9688732"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53190"/>
    <dbReference type="eggNOG" id="KOG0543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="433738at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF1">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="438" mass="47680" checksum="BA1A5A03E4071C13" modified="2009-05-26" version="1">MASSEGFAVTSYATPPAFAPAIELDDGHVVVRLARNALATRDAKRVDANSRVALRLRVAPGPGERGGGDDDDDAASSKATTHVVHVDGALVEGVETALLRGGEDGAGMTAGDVFLVSCTMDRTLTDDAPLFAPGAIDITKRRYDETHFEVDVLAVEDAWPGKISGTAKQKLERGEALKRLGNKLLKEGRARRAEVKYAAGVEMFTVMGAEFVHSNVPTAEETKTNRDAEAMGAALYNNLAVCLMKRDAFHDAEIACTEALDLSPGNIKALLRRGTCRIDTLKWDEAEVDFFAALKHAAAANDTKAFFALEHDLHKQRMRLKSMRKAQDAKDLEVVSGMFDRLSGKAHQRAHDAVARRRIQKKRDKSATWYDAADVALPGEAFPMTGTRAQSAIKIDVIDAEIAAEEEEEADEARADKSEMYNTLLRTGAMRMYNPDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6Q3</accession>
    <name>C1N6Q3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_48922</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063774.1">
        <property type="nucleotide sequence ID" value="XM_003063728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6Q3"/>
    <dbReference type="GeneID" id="9689215"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48922"/>
    <dbReference type="OMA" id="WRETWTE"/>
    <dbReference type="OrthoDB" id="515259at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="395"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="162"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="453"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="540"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="584"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="453"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="550"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH52147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="702" mass="71959" checksum="38D13993510BDFD3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N782</accession>
    <name>C1N782_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53589</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063691.1">
        <property type="nucleotide sequence ID" value="XM_003063645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N782"/>
    <dbReference type="GeneID" id="9689294"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53589"/>
    <dbReference type="OMA" id="DEHWRES"/>
    <dbReference type="OrthoDB" id="10692529at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="747"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="966"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="640"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="676"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="798"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="810"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="851"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="899"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="968"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1094"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1110"/>
            <end position="1120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1127" mass="115282" checksum="D56C272A2831B3DB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1N785</accession>
    <name>C1N785_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Dynein-1, subspecies f</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">IA1-DHC1B</name>
        <name evidence="21" type="ORF">MICPUCDRAFT_45975</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Force generating protein of eukaryotic cilia and flagella. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for assembly of the I1 inner arm complex and its targeting to the appropriate axoneme location. Also required for phototaxis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">The I1 inner arm complex (also known as the f dynein complex) is a two-headed isoform composed of two heavy chains (1-alpha and 1-beta), three intermediate chains and three light chains. I1 occupies a specific position proximal to the first radial spoke and repeats every 96 nm along the length of the axoneme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063693.1">
        <property type="nucleotide sequence ID" value="XM_003063647.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N785"/>
    <dbReference type="GeneID" id="9689295"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45975"/>
    <dbReference type="eggNOG" id="KOG3595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ILKNDMQ"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036156">
        <property type="term" value="C:inner dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036159">
        <property type="term" value="P:inner dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000153">
        <property type="entry name" value="Dynein axonemal heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000001">
        <property type="entry name" value="dynein heavy chain 17, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000002">
        <property type="entry name" value="Dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000008">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000044">
        <property type="entry name" value="Dynein heavy chain 5, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000009">
        <property type="entry name" value="Dynein heavy chain 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000049">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056759">
        <property type="entry name" value="DYH2-5-8_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF32">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25007">
        <property type="entry name" value="DYH2-5-8_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="11 19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="1664"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="2278"/>
            <end position="2424"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="2628"/>
            <end position="2786"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="3091"/>
            <end position="3170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00054075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00063032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00077719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EEH52066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="4304" mass="486135" checksum="76C69E1FCDBAEC54" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N796</accession>
    <name>C1N796_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_49003</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063859.1">
        <property type="nucleotide sequence ID" value="XM_003063813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N796"/>
    <dbReference type="GeneID" id="9689140"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49003"/>
    <dbReference type="OrthoDB" id="745551at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="888"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1148"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1177" mass="126384" checksum="670C0EB5AE8FE915" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Q2</accession>
    <name>C1N7Q2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53787</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064132.1">
        <property type="nucleotide sequence ID" value="XM_003064086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Q2"/>
    <dbReference type="GeneID" id="9689389"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53787"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="184" mass="18917" checksum="8FB03C33150553A9" modified="2009-05-26" version="1">MASSSSCNNAAARASSSPSRRCSCHDGDASMSAREMPGSSPVDVRTTTASSSSSSPAAAASSDPKLRGCFLFVVFAVVVVVVALVVGGGAAAARRLGGFEGLNSLLRGCVENPPRTLFAADAYPPTPTPPPYCDRCRASASSAFRSRRSSVIVASRAFGSFHTSERRGGVERRQLKLKGAEGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Q3</accession>
    <name>C1N7Q3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_30096</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064133.1">
        <property type="nucleotide sequence ID" value="XM_003064087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Q3"/>
    <dbReference type="STRING" id="564608.C1N7Q3"/>
    <dbReference type="GeneID" id="9689574"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30096"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EDAMKWY"/>
    <dbReference type="OrthoDB" id="509488at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="357" mass="39943" checksum="1CC339E4EC7DFE4E" modified="2009-05-26" version="1" fragment="single">MKWFLKAAAQGHAGSMTIIGGFYFHGRGVEQNKSTAREWWKKAAANGDDEAKEMLMNRFGDDDASVDRVTRHFARGDDPSVDREAEVKLPRNIRDLAKKANAGCGEAARTIAWHFFHGTDGVEKDTELHFRWLVKAAELGDAKAQCRIGSEYNQMSNYDAARKWFDKAAAQGNADAMNNLGALYYKGQGVEKNISTAAEWYLKAAMKGNSHAQYTYGALLDIDMNQHEDAMKWYLKAAAQGDANAMNNLALLYFNGKGVERNVSTAAEWFLKAASKGDREAQCNYGNILFEEMGQYEDAMKWYMKAAAQGHAEATHNIGTLYFRGDGVEQNKWTAREWWEKAAAYGCEEAKTNLLKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7T2</accession>
    <name>C1N7T2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitochondrial protein translocase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_8521</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064146.1">
        <property type="nucleotide sequence ID" value="XM_003064100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7T2"/>
    <dbReference type="STRING" id="564608.C1N7T2"/>
    <dbReference type="GeneID" id="9689405"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8521"/>
    <dbReference type="eggNOG" id="KOG3225">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RIAYPYR"/>
    <dbReference type="OrthoDB" id="1913277at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039205">
        <property type="entry name" value="NDUFA11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21382:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21382">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="126" mass="12143" checksum="F323BEB01BF592D2" modified="2009-05-26" version="1" fragment="single">MSHESSCLAQTSSSAAAGFFVGTLAGGLGAMWDRVPAVMQNRSLPALAKTAGVMGSTGGVLAAIGAAYSGAKCASAGIRGEDDIWNGVVGALAAGQIFGVRGRSVGLGLGCGATLAVVSATLDARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8M2</accession>
    <name>C1N8M2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54142</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064291.1">
        <property type="nucleotide sequence ID" value="XM_003064245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8M2"/>
    <dbReference type="GeneID" id="9689550"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54142"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="166" mass="19050" checksum="B0963F7155EA28AD" modified="2009-05-26" version="1">MDRIEGIHIRLPPGSEWPYKKLHDGVTLDRMRLKGTTVAAWDLRCLDFYVKHDRSKVKTFDEGPFDVWGCMDGAFVCEELLCGRGVGVCVICEGTDTNVMCEYCANDSNGGEICECCRAWVCGLHSSDEIDGIMASCDRCEWTTCRECHDKRFFEWGELWCRRHDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1N965</accession>
    <name>C1N965_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_49227</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:20630"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:47005"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064399.1">
        <property type="nucleotide sequence ID" value="XM_003064353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N965"/>
    <dbReference type="STRING" id="564608.C1N965"/>
    <dbReference type="GeneID" id="9690006"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49227"/>
    <dbReference type="eggNOG" id="KOG0373">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MCLKVKY"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000005">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="8">
        <location>
            <begin position="110"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="306" mass="34773" checksum="06C9DFA3170A0883" modified="2009-05-26" version="1">MGKLDLDAWIAKIKQCEPLEEAELEALCAYVKEVLVEESNVQPVCSPVTVCGDIHGQFHDLLKLFETGGDVPDTNYIFMGDFVDRGYNSLETFTLLLLLKARWPQCVTLLRGNHESRQITQVYGFYDECQRKYGNANAWRWCTDVFDYLTLSALIDGEVLCVHGGLSPDVRTLDQVRTIDRLCEIPHEGPFCDMMWSDPEDIETWSVSPRGAGWLFGRKVTAEFNAINGLNLIARAHQLVQEGLKYTFPEKSLVTVWSAPNYCYRCGNVASMLAFDDKMERTVKYFTETPENSTMMAPRASVPYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9E4</accession>
    <name>C1N9E4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">[phosphatase 2A protein]-leucine-carboxy methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.233</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">[Phosphatase 2A protein]-leucine-carboxy methyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_4965</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine = [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:48544"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="2.1.1.233"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. LCMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.233" evidence="3"/>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064606.1">
        <property type="nucleotide sequence ID" value="XM_003064560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9E4"/>
    <dbReference type="STRING" id="564608.C1N9E4"/>
    <dbReference type="GeneID" id="9689878"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4965"/>
    <dbReference type="eggNOG" id="KOG2918">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IIYEPIR"/>
    <dbReference type="OrthoDB" id="497137at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018423">
        <property type="term" value="F:protein C-terminal leucine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016651">
        <property type="entry name" value="LCMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600:SF21">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016305">
        <property type="entry name" value="LCM_mtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="182"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016305-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="341" mass="37294" checksum="931D612CFBCBB259" modified="2009-05-26" version="1" fragment="single">RPTDAAVRLTNDEASVAKARCHELGYFDDPLAAAFAPRGPAKRGGGGTHHEPLINRGYYARVRAMRAMIDAFMDASLPGDDDEDDDRDIVSLGAGFDTSYFRLLAAGRAPGLFVEVDYGEVARKKAEIVRARRERFFGDREDEMTNALVNLADGSYHGDGGGGDDDDASFRDVFGYRLLSADLRDVATLERKLLDLPGYDAEIPTLFLAECCLAYVEPEEAAAVIALAARLSSSAPAAAFVLYDPIGPDDAFGVQMGLNLRARGCPLRGVAGAPTLEAQRERFQARGWARAGAMDMNDACDRLARRDASDHLRMTRLEMLDEVEEFRMMLAHYCVAWGVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9T4</accession>
    <name>C1N9T4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">WEE1</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_54624</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064670.1">
        <property type="nucleotide sequence ID" value="XM_003064624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9T4"/>
    <dbReference type="STRING" id="564608.C1N9T4"/>
    <dbReference type="GeneID" id="9690231"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54624"/>
    <dbReference type="eggNOG" id="KOG0601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5337378at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF189">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="377"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="35"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="110"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="673"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="727"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="314"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="673"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="691"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="739"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="750" mass="78721" checksum="658D36CBB3FB9101" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9V3</accession>
    <name>C1N9V3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_6581</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064681.1">
        <property type="nucleotide sequence ID" value="XM_003064635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9V3"/>
    <dbReference type="GeneID" id="9690122"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6581"/>
    <dbReference type="eggNOG" id="KOG4601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FFIGRHP"/>
    <dbReference type="OrthoDB" id="447510at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019799">
        <property type="term" value="F:tubulin N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03130">
        <property type="entry name" value="mec17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038746">
        <property type="entry name" value="Atat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007965">
        <property type="entry name" value="GNAT_ATAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12327">
        <property type="entry name" value="ALPHA-TUBULIN N-ACETYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12327:SF0">
        <property type="entry name" value="ALPHA-TUBULIN N-ACETYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05301">
        <property type="entry name" value="Acetyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51730">
        <property type="entry name" value="GNAT_ATAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="159" mass="18003" checksum="90DA5A8F9DEA63AA" modified="2009-05-26" version="1" fragment="single">DEHRAMAALLEEAGRLSARAQALPAPITSLERLHADQRLYIASHDASDPSRGPSVVLGFLKVGEKRLFVSDPRGNTVEIEPCCVLDFYVHESCQRGGIGSELFARFLEEEDHRPARLAYDRPSHKLKSFLRKHFGLVSFSPNANNYVVFRDYWDAPRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9X4</accession>
    <name>C1N9X4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anthranilate synthase component 2</fullName>
            <ecNumber evidence="3">4.1.3.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Anthranilate synthase, glutamine amidotransferase component</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_23759</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Tetramer of two components I and two components II.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="3"/>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064810.1">
        <property type="nucleotide sequence ID" value="XM_003064764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9X4"/>
    <dbReference type="STRING" id="564608.C1N9X4"/>
    <dbReference type="MEROPS" id="C26.A09"/>
    <dbReference type="GeneID" id="9690251"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23759"/>
    <dbReference type="eggNOG" id="KOG0026">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IGLYHSW"/>
    <dbReference type="OrthoDB" id="524799at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000003">
        <property type="entry name" value="Anthranilate synthase component II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050472">
        <property type="entry name" value="Anth_synth/Amidotransfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418:SF4">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="9">
        <location>
            <begin position="74"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00082672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH51144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="273" mass="29669" checksum="BFDDAF24F837DC09" modified="2009-05-26" version="1">MSVAATTTTTIAKASPARGLAARSTAATTTTGGLGLGRRRRSSDAARRRRRGVARRVGVVVLAAASKGDDRPVVIIDNYDSFTYNLSQYLGDLGCEHVVYKNDEKTVAEIAAMNPKGVMVSPGPGRPEDSGISLEACEKLGPEFGVFGVCMGHQCIGQVFGGTVVRAPCGLMHGKSSPVWHTEEEGQLLHGLPRRVPISRRPFEAARYHSLVISREGFPEDELEVTAWTKDQTIMAVKHRKYPKIQGVQFHPESIITENGLHIIRNWVNLIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Y5</accession>
    <name>C1N9Y5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54689</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064814.1">
        <property type="nucleotide sequence ID" value="XM_003064768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Y5"/>
    <dbReference type="STRING" id="564608.C1N9Y5"/>
    <dbReference type="GeneID" id="9690255"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54689"/>
    <dbReference type="OrthoDB" id="188741at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037386">
        <property type="entry name" value="CCDC40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275:SF8">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="95" mass="10827" checksum="C84E7157779F4A01" modified="2009-05-26" version="1">MRKDTLRINELSAKHLKRKDALLTDNHVLETEIVGELKDLEVAAVELEGKIEAAVEEKRVTLANVVEAERQIMLWERKIQARSPHTGSHTTAFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA04</accession>
    <name>C1NA04_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Choline transporter like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_54711</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064704.1">
        <property type="nucleotide sequence ID" value="XM_003064658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA04"/>
    <dbReference type="GeneID" id="9690267"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54711"/>
    <dbReference type="eggNOG" id="KOG1362">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CQIALHG"/>
    <dbReference type="OrthoDB" id="420519at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF14">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="521"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="562"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="616"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="708"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="743"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="827"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="827"/>
            <end position="860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="867" mass="94955" checksum="6542196ECBE22CD2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAA1</accession>
    <name>C1NAA1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54817</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064759.1">
        <property type="nucleotide sequence ID" value="XM_003064713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAA1"/>
    <dbReference type="GeneID" id="9690309"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54817"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="115" mass="11726" checksum="EEED195669F2B30F" modified="2009-05-26" version="1">MPPPPNPAPSRRRSLPPPPRPLAAAAAAAADARALASLERETTRSAAAAAKAAADAVAVADATLTELSSQTVQLERVGDDLATCDDAVRGSERTLRKVSRGGVPHTGSHTTPSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAN2</accession>
    <name>C1NAN2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_23895</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663755">
        <property type="protein sequence ID" value="EEH50844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAN2"/>
    <dbReference type="eggNOG" id="ENOG502S4NT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="783061at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33220">
        <property type="entry name" value="BNAA09G04420D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33220:SF5">
        <property type="entry name" value="RRNA INTRON-ENCODED HOMING ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="81" mass="9334" checksum="B52FE09B5ED706D6" modified="2009-05-26" version="1">MKNVAKCDTWCELQNPVNHRVFERKLRPKPSGRGHVCLGVTNRRPPSSFKDSGRKLVSRVLPHAVDRNPSQGCLERPDMRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGG3</accession>
    <name>C1MGG3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-coa-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ACBP</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_46091</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ACBP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054769.1">
        <property type="nucleotide sequence ID" value="XM_003054723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGG3"/>
    <dbReference type="STRING" id="564608.C1MGG3"/>
    <dbReference type="GeneID" id="9680705"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46091"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0817">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IEHSKWT"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF3">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACB" evidence="7">
        <location>
            <begin position="7"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="141"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="578"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="628"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="728"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="697"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="584"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="633"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="775" mass="80442" checksum="832B24C8576A64CC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGH5</accession>
    <name>C1MGH5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_70774</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054776.1">
        <property type="nucleotide sequence ID" value="XM_003054730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGH5"/>
    <dbReference type="STRING" id="564608.C1MGH5"/>
    <dbReference type="GeneID" id="9680756"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70774"/>
    <dbReference type="eggNOG" id="ENOG502R6PD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VINKWIP"/>
    <dbReference type="OrthoDB" id="3846at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.280">
        <property type="entry name" value="Cobalamin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="entry name" value="tm_1862 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023862">
        <property type="entry name" value="CHP03960_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018768">
        <property type="entry name" value="DUF2344"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045784">
        <property type="entry name" value="Radical_SAM_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03960">
        <property type="entry name" value="rSAM_fuse_unch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03936">
        <property type="entry name" value="sam_1_link_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42731:SF1">
        <property type="entry name" value="RADICAL SAM DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42731">
        <property type="entry name" value="SLL1084 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10105">
        <property type="entry name" value="DUF2344"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19864">
        <property type="entry name" value="Radical_SAM_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01082">
        <property type="entry name" value="B12-binding_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="341"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1084"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1142" mass="124597" checksum="D4CD1E7EA36504C8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHK3</accession>
    <name>C1MHK3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Intraflagellar transport protein 122 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">IFT122</name>
        <name evidence="13" type="ORF">MICPUCDRAFT_46242</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055508.1">
        <property type="nucleotide sequence ID" value="XM_003055462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHK3"/>
    <dbReference type="STRING" id="564608.C1MHK3"/>
    <dbReference type="GeneID" id="9681218"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46242"/>
    <dbReference type="eggNOG" id="KOG1538">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GDSFDTW"/>
    <dbReference type="OrthoDB" id="10255582at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000176">
        <property type="entry name" value="Intraflagellar transport protein 122 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056153">
        <property type="entry name" value="Beta-prop_IFT122_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056152">
        <property type="entry name" value="Beta-prop_IFT122_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039857">
        <property type="entry name" value="Ift122/121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057411">
        <property type="entry name" value="TPR_IFT122"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056838">
        <property type="entry name" value="Zn_ribbon_IFT122"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764:SF4">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764">
        <property type="entry name" value="WD REPEAT DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23381">
        <property type="entry name" value="Beta-prop_IFT122_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23377">
        <property type="entry name" value="Beta-prop_IFT122_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25295">
        <property type="entry name" value="TPR_IFT122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25144">
        <property type="entry name" value="Zn_ribbon_IFT122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT122 first beta-propeller" evidence="10">
        <location>
            <begin position="2"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="IFT122 second beta-propeller" evidence="9">
        <location>
            <begin position="299"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Intraflagellar transport protein 122 homolog TPR" evidence="12">
        <location>
            <begin position="560"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="domain" description="IFT122 zinc ribbon" evidence="11">
        <location>
            <begin position="1007"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1201"/>
            <end position="1220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH60760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1233" mass="138427" checksum="C1B674D2DD9ED462" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHK9</accession>
    <name>C1MHK9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_37917</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054972.1">
        <property type="nucleotide sequence ID" value="XM_003054926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHK9"/>
    <dbReference type="STRING" id="564608.C1MHK9"/>
    <dbReference type="GeneID" id="9680694"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37917"/>
    <dbReference type="eggNOG" id="KOG3794">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CSMYSIS"/>
    <dbReference type="OrthoDB" id="6253837at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040014">
        <property type="entry name" value="CIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13151">
        <property type="entry name" value="CBF1 INTERACTING COREPRESSOR CIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13151:SF2">
        <property type="entry name" value="COREPRESSOR INTERACTING WITH RBPJ 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="2">
        <location>
            <begin position="25"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="344" mass="39419" checksum="BDE76B81FA654219" modified="2009-05-26" version="1">MQAEKLGLKPRGGTAWSHGFLNQKDWHPLSYRNQEKLFKAEQEAENAKKRKEAAAKEFAVEQEFFKNTELLSAEDRTTLRNKQQLSFMYQKPPGYDAAMEREKAEAEEAREAERKELKRKEDAAAREAAGLPPLTEEEINERRGRRMKKDMYGRNIISEVEMPELKGAPKEKGVGVANVKVFGKHVRAVQCLRCGGFGHSNDEKTCPMFGHNPNDEFRVKLEDPLTLMRAREELTKMKKFEMKTPMTGRSPTRGGGDPNAANQQLLHDVDVQDALEGGTGTETGEGGILDSLPKAERKRLIREYKAKEKEEKRARVVAAEEFLKNHAKRERKEKKRKKDRKEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHS7</accession>
    <name>C1MHS7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50306</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055006.1">
        <property type="nucleotide sequence ID" value="XM_003054960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHS7"/>
    <dbReference type="STRING" id="564608.C1MHS7"/>
    <dbReference type="GeneID" id="9681112"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50306"/>
    <dbReference type="eggNOG" id="ENOG502SCZY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QNINAMQ"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051100">
        <property type="entry name" value="DnaJ_subfamily_B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908:SF3">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="226"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="99"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="281" mass="29087" checksum="E88A243940454046" modified="2009-05-26" version="1">MYGGGGRGGRGGGRGGKNVWVRPGAAAPAPAPATTTTAAKTTPFAPAASAPLRAAAASYTPSGEAFLPVGVKRRADASAAAADPDAHKRYRASTPPPDAAALERAAKAAEAKAALEKKLADAREEAEKMKAAIKAAAARAKEKKEAAARDAAAAKELEKKEAALEKANKAKKASNLLSGFAAARKKQGVGTAEGAEATLRAEAAAAELTPEERERQAVRRVMMAGTDWQILNLPPDAQAKWVKQSYRELAKVLHPDKCKAAGAKDAFQKVAKAYQNITSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHZ4</accession>
    <name>C1MHZ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50375</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055577.1">
        <property type="nucleotide sequence ID" value="XM_003055531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHZ4"/>
    <dbReference type="GeneID" id="9681003"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50375"/>
    <dbReference type="OMA" id="DPMGAPD"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="133" mass="14387" checksum="E27DCC177A001C18" modified="2009-05-26" version="1">MAERDESYRGRGSAPESPVGARESPRARDANVGSDNEGEFDDDEDRTFDSADFDERDGGFRDSDTDTDSEAAGGGAGVLGCVSYLWMLVAMGIFAYLIVTVQSQADVIKTMQRKVATMEQRLGLSPMMTASEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIF9</accession>
    <name>C1MIF9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_50552</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055123.1">
        <property type="nucleotide sequence ID" value="XM_003055077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIF9"/>
    <dbReference type="STRING" id="564608.C1MIF9"/>
    <dbReference type="GeneID" id="9680949"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50552"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1995">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76445at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="11">
        <location>
            <begin position="210"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="262"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="74"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="175"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="375"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH60375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="432" mass="42554" checksum="84E9593387FCFD25" modified="2009-05-26" version="1">MVGNMSYDTSEQTLAGAFGHLGRITDCKVITDRDTGRPKGFAFITFDDPNAAMQAVQTMSGQNVDGRSVRVEMAKDSRGGGGGGGGGGGYGAPPGPPGPPSGGGYPPPPPPGGGGGGGGGAPNPNDPWGIGGGAPGLGGGGGGGGGGGGRGVCFDFQKGQCNRGASCRYSHGDAPGGGGGGGGGGRDSYGGGGGGGGGGFRDPEPPKVVPGGDWNCDTCGNSNFSWRKACKKCNKPKSKELKDAEQKATAGWLHDGLDDTSNRIFIKGFDPAEVKEDDLKELFGGIGIISRVRQKFGFPDEWPHAVKIYKDESGRPKDEALITYDDPMAAQSAPGFYDGYELKGKKLQVSIATASKKKDDDGGGGYGGGGGGGYGGGGGGGYGGGPDRGRGGYGGGGRDNYRGGGGYRGGGGGGGGGGGRDNRGGGGYGRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIM6</accession>
    <name>C1MIM6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_1653</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055692.1">
        <property type="nucleotide sequence ID" value="XM_003055646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIM6"/>
    <dbReference type="STRING" id="564608.C1MIM6"/>
    <dbReference type="GeneID" id="9680872"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_1653"/>
    <dbReference type="eggNOG" id="KOG0127">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12414">
        <property type="entry name" value="RRM2_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12415">
        <property type="entry name" value="RRM3_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12416">
        <property type="entry name" value="RRM4_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000182">
        <property type="entry name" value="RNA-binding motif protein 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="8"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="169"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="331"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="100"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="152"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="438" mass="47772" checksum="3CD5B0408B03894C" modified="2009-05-26" version="1" fragment="single">EGARPKSWRVIVRNVSFKAAEAEIRAAMSAAGFVWELTIPKDFHGKPKGFAFAAYTRKADAERAVKEVNATAIAGRQIAVDWAMSKHEYNEAQLKQKEEEGAEEESEEGSDGEDDDGSGSESESESGDDSGSEYESESESSSESESDDSDSQPPPLPGKGAKTPPPAGASVFVRDLPTDASKQSLFERMQKFGKVRSCRVVLDKTTGRSKGTAFVDFVDAASASRAIEAAGKVEGGGVKVAGRRLNIALAVSATDAADLATAKSKAFATDAKKRRDGPRDNRNLYLATEGQIHEEGPAAQGVSREDIMKRRRAKEEQKMKLKNPNFFISKNRLQVRNVPPEVDQKQLKKIFHDAVLQRATKANPKVLHARLLIDNTRPDANGKPRSRGIGFVEFDAHDHALAALRTLNNNPTIFTAAKRPIVEFAVEDARAVKKLERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIQ3</accession>
    <name>C1MIQ3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50655</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055706.1">
        <property type="nucleotide sequence ID" value="XM_003055660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIQ3"/>
    <dbReference type="GeneID" id="9680728"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50655"/>
    <dbReference type="eggNOG" id="ENOG502S5HM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MCATSKG"/>
    <dbReference type="OrthoDB" id="498157at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="582" mass="60223" checksum="43FB6F78B2D9F844" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ60</accession>
    <name>C1MJ60_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">fructokinase</fullName>
            <ecNumber evidence="11">2.7.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_46426</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.4" evidence="11"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055777.1">
        <property type="nucleotide sequence ID" value="XM_003055731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ60"/>
    <dbReference type="STRING" id="564608.C1MJ60"/>
    <dbReference type="GeneID" id="9680413"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46426"/>
    <dbReference type="eggNOG" id="ENOG502QRD3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DIQAYYI"/>
    <dbReference type="OrthoDB" id="10260668at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd24067">
        <property type="entry name" value="ASKHA_NBD_ROK_BsFRK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000153">
        <property type="entry name" value="Putative fructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051804">
        <property type="entry name" value="Carb_Metab_Reg_Kinase/Isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049874">
        <property type="entry name" value="ROK_cs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42742:SF3">
        <property type="entry name" value="FRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42742">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR MPRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="482"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="497"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH61029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="512" mass="53109" checksum="09B011EB3D9E46DE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ96</accession>
    <name>C1MJ96_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50860</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055273.1">
        <property type="nucleotide sequence ID" value="XM_003055227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ96"/>
    <dbReference type="GeneID" id="9680467"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50860"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="182" mass="19364" checksum="E2C7199F616BA734" modified="2009-05-26" version="1">MTDASATPTRAYRPLDVDAANASTRRGVADDDSVPDGSGTPGSPTRIGSRTRWTKDDASASTSGGGGGDDASVMTQVTRSGGLERPKYGRDNQPQSFKRPDRIQSRSDAAAGGARREDKKSGGGGWFAALFCCGKPRDDDDSPRQVRARAASVGGLERAMPLPSQFNNIQFSERFPPFHEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJE7</accession>
    <name>C1MJE7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_38292</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055302.1">
        <property type="nucleotide sequence ID" value="XM_003055256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJE7"/>
    <dbReference type="STRING" id="564608.C1MJE7"/>
    <dbReference type="GeneID" id="9681223"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38292"/>
    <dbReference type="eggNOG" id="ENOG502QPSS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PWRILVK"/>
    <dbReference type="OrthoDB" id="515480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36365">
        <property type="entry name" value="OS05G0500400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36365:SF1">
        <property type="entry name" value="OS05G0500400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1995" evidence="1">
        <location>
            <begin position="87"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="373" mass="38110" checksum="18822B1A2C7BE2CC" modified="2009-05-26" version="1">MAMSRASFAPIAPARRAAAAAAAARTRAPSSTTFGSIVPSRKNIQRRRRRETMIPVAASSSSSRRSLVVVAGGAAAGAGGEMELLPPVSRDESFEQARVAIDAVVSKRAKKSGKKRKSSGKSLAQLRVAVELPLASDAPSAVCAMVRGACGGGTVSTAVYGDPECATLAAGKTKAENDGIAEHVSLDDALRGDGCDLAVGTGAVALVGVPDDEIGKARRVAELSGGRPIVGVNVEWEHAGDGGVSFRGTPAASTATPDETFANSFSVVYSYLPLAIQGIAGDTTEGAVFKCVRGGAPEGSPWRILVKDDGKEYQQVGAMRRRPGAEDLESALYNAAAAKSPVNKGIGVFRGLADKVKNSIPNPLDGLGGGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2024-03-27" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKQ7</accession>
    <name>C1MKQ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_70885</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056038.1">
        <property type="nucleotide sequence ID" value="XM_003055992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKQ7"/>
    <dbReference type="GeneID" id="9681523"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70885"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="239" mass="26886" checksum="8FB868C34D2A80E1" modified="2009-05-26" version="1">MVIPAGPSVFLKGKNFSRVGLVRLWDLGESTRQLLADEFVATWPARHGESNSIRRKDFSLTQDSVPLVLVPFDGPDSGKLVLGYVVIYSSSSIYRNEQSREGAFKREEPHDSWETVANCSLNSVFVPRLFRGCHLGQVLVKLAVYVAFNELRFECVTAWCQADKISFYSSCGLNSEQPGSHMTPGVERERKLGDRTLWKTAISESVHGANYAQSVVMRQNGLSHLDWCMRIFRVHLSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKT1</accession>
    <name>C1MKT1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_46544</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056050.1">
        <property type="nucleotide sequence ID" value="XM_003056004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKT1"/>
    <dbReference type="GeneID" id="9681977"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46544"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="208" mass="22325" checksum="18AE041B2BCAD3A2" modified="2009-05-26" version="1">MGLDSEVTRTLGDVVVPHPFKGDGRAKYNGQRPAATRSPANIQPSEIVLEAEKKKLNWYGNIPEGRSFSLVPMAIDTYGFKAPRFSKFLNQLADHGARGTVPAGDAASEAATEATISAIARSKSYWKRRIMGHISVALVYAIGDRIAGAPISYALRTARDSENFHAGAAAQILFMEPDTAGDFHIAPAPCAREAHMGFMNPVVGLLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML99</accession>
    <name>C1ML99_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55633</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056521.1">
        <property type="nucleotide sequence ID" value="XM_003056475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML99"/>
    <dbReference type="GeneID" id="9681573"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55633"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="112" mass="13050" checksum="3F985F8E4B15009E" modified="2009-05-26" version="1">MALRIRRYDRKYEGTFEGITSCVLRKYFCTEVLPEVHCSVMSICYNITRATYFAPRLSCNLLLKYFRSISVGPTCTCRTCFRKYYPFSGSTSVQRCTFGTVRVRKSFRGSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLV5</accession>
    <name>C1MLV5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_62277</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057285.1">
        <property type="nucleotide sequence ID" value="XM_003057239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLV5"/>
    <dbReference type="GeneID" id="9682724"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62277"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00603">
        <property type="entry name" value="IPT_PCSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IPT/TIG" evidence="1">
        <location>
            <begin position="397"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="616" mass="60202" checksum="ACE5DCD64D33B6E5" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLW4</accession>
    <name>C1MLW4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_8718</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057290.1">
        <property type="nucleotide sequence ID" value="XM_003057244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLW4"/>
    <dbReference type="STRING" id="564608.C1MLW4"/>
    <dbReference type="GeneID" id="9682729"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8718"/>
    <dbReference type="eggNOG" id="KOG0667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GKDERDQ"/>
    <dbReference type="OrthoDB" id="25592at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF28">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MINIBRAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="143" mass="15843" checksum="5F58EC812114B717" modified="2009-05-26" version="1" fragment="single">CLVFELLSHSLYNVLQSTKFHGVSLGLIRKFTKQLVSALAYLRSHGVVHCDLKPENVLLCGVDRSAIKLIDFGSSGWAGETDDNTYVQSRFYRAPEVILGLPYGCAVDVWSLGCIMVEMHGGKPLFPGKDERDQLWKISEALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLZ8</accession>
    <name>C1MLZ8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA topoisomerase 6 subunit B</fullName>
            <ecNumber evidence="6">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">TOP6B</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_32362</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Heterotetramer of two TOP6A and two TOP6B subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TOP6B family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="6"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057307.1">
        <property type="nucleotide sequence ID" value="XM_003057261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLZ8"/>
    <dbReference type="STRING" id="564608.C1MLZ8"/>
    <dbReference type="GeneID" id="9682746"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32362"/>
    <dbReference type="eggNOG" id="ENOG502QQC0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VYRGNPF"/>
    <dbReference type="OrthoDB" id="1562195at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009330">
        <property type="term" value="C:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00823">
        <property type="entry name" value="TopoIIB_Trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00322">
        <property type="entry name" value="Top6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005734">
        <property type="entry name" value="TopoVI_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015320">
        <property type="entry name" value="TopoVI_B_transducer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003218">
        <property type="entry name" value="PRK04184.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48444">
        <property type="entry name" value="DNA TOPOISOMERASE 6 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48444:SF1">
        <property type="entry name" value="DNA TOPOISOMERASE 6 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09239">
        <property type="entry name" value="Topo-VIb_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="DNA topoisomerase VI subunit B transducer" evidence="8">
        <location>
            <begin position="387"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="167"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="176"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="679" mass="74607" checksum="E26C2C6476541C25" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM27</accession>
    <name>C1MM27_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_38805</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057323.1">
        <property type="nucleotide sequence ID" value="XM_003057277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM27"/>
    <dbReference type="STRING" id="564608.C1MM27"/>
    <dbReference type="GeneID" id="9682762"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38805"/>
    <dbReference type="eggNOG" id="ENOG502S2BF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PCMEDAF"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010658">
        <property type="entry name" value="Nodulin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF158">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 12-LIKE CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06813">
        <property type="entry name" value="Nodulin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="577"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Nodulin-like" evidence="6">
        <location>
            <begin position="8"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="619" mass="63434" checksum="69F722B09250B48C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN13</accession>
    <name>C1MN13_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_46866</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057022.1">
        <property type="nucleotide sequence ID" value="XM_003056976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN13"/>
    <dbReference type="STRING" id="564608.C1MN13"/>
    <dbReference type="GeneID" id="9682941"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46866"/>
    <dbReference type="eggNOG" id="KOG2734">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TDWREQE"/>
    <dbReference type="OrthoDB" id="1898821at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:001136">
        <property type="entry name" value="Beta-catenin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039678">
        <property type="entry name" value="CTNNBL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013180">
        <property type="entry name" value="CTNNBL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978:SF0">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08216">
        <property type="entry name" value="CTNNBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01156">
        <property type="entry name" value="DUF1716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Beta-catenin-like protein 1 N-terminal" evidence="7">
        <location>
            <begin position="20"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="568" mass="61505" checksum="92CA4E05657D2F4C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN38</accession>
    <name>C1MN38_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_39033</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057037.1">
        <property type="nucleotide sequence ID" value="XM_003056991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN38"/>
    <dbReference type="GeneID" id="9682476"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39033"/>
    <dbReference type="OrthoDB" id="10686642at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="388" mass="41577" checksum="E45BA17C514C21CE" modified="2009-05-26" version="1">MQGRGLQGRGLGSRASSSQYTESQYTESDDDDDDDDDDARQQQQQMRDEHDAEQTEPPQQQATHPQQHHHPPPSAAGAEARDLELQRREIELEKQRLAMASKLILEAQRMEDGRRQQTGGQPSAAAIPAAAATANAMTTASAHPRAYEGHPLLAPLATLSGASGSERLVAAMEHVDRVVNAFSEDIGRAVANIRAESFEAHREKQEADLELRWTELRREREQEKAERTRAERELREASARATAETQAAALVQMQAAQAAQAASYGFGGGFGEALGPGTGPAEPREAATYGGLPGGARGEGAVRIPPDGGGSYPYPYPEPDPYAYAHASSSSARGAVGVGEKPPPGASVVLALGGLRRADAPTRAAEAYEVRSIYWFPYGRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN73</accession>
    <name>C1MN73_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mRNA export factor GLE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleoporin GLE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_62692</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057530.1">
        <property type="nucleotide sequence ID" value="XM_003057484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN73"/>
    <dbReference type="STRING" id="564608.C1MN73"/>
    <dbReference type="GeneID" id="9682493"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62692"/>
    <dbReference type="eggNOG" id="KOG2412">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ESWAWIA"/>
    <dbReference type="OrthoDB" id="420884at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012476">
        <property type="entry name" value="GLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960">
        <property type="entry name" value="GLE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960:SF0">
        <property type="entry name" value="MRNA EXPORT FACTOR GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07817">
        <property type="entry name" value="GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="20"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="22"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH59175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="420" mass="46741" checksum="204C5A81ECBF90E7" modified="2009-05-26" version="1">MDARWRQRDAAVRVVLAADAAEAERQRAAAEAEEKARKAAEEAKRRAEEEEKKKAEAAAKAKSDAEKAAAATAAEEKRRMEEEKKAAEAAATAPGAPPRPGVVPRVQTSAEASAREGEFAAELARARTSVAEYSTSASTKRERRALNAQITVHVQQIAATKTQIEKKAIDVATMLSNVRQEPQRTFALVSLAKRILTQCDSQVSKLNRFAFALAEVAVRIAVFEPRFNVILLALLHESCVLAVPKYYPFVVGRYASDDEYFRLMGYVDAEDQGERREGDPPKLETTDAFGQRLRGFMLFYAAYTQVEHATHPHGMEAAWSWISRLLNRIPPNRHSATALESFLKHAGYRMYATYGSQFGKILDVVDQSFLPELEAKSGDDPDVRPVASRTRTYLNERTFLKPPEGREMPNTDTSQNTIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNK5</accession>
    <name>C1MNK5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_3691</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057122.1">
        <property type="nucleotide sequence ID" value="XM_003057076.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNK5"/>
    <dbReference type="STRING" id="564608.C1MNK5"/>
    <dbReference type="GeneID" id="9682561"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3691"/>
    <dbReference type="eggNOG" id="KOG1371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HFAAHTI"/>
    <dbReference type="OrthoDB" id="9402762at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF53">
        <property type="entry name" value="UDP-ARABINOSE 4-EPIMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01713">
        <property type="entry name" value="NUCEPIMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="339" mass="37154" checksum="61C6112E8907B916" modified="2009-05-26" version="1" fragment="single">HVLVTGGAGFIGSHATMRLLELGHAVTIVDNYSRGNRGAVRALQKLAPPRKLRVVEADIGIPEELERAFDPRYPIDVVMHFAAIAFVGEAMEKPLLYYHNVTSNTVGVLEAMKRHKVKRLVYSSTCATYGNPDVMPITEKTPTAPINAYGRSKLYSENAVRDHAKSDPGFDAAILRYFNVFGADPRGRLGEYPPPSLMHHGRISTACFDAALGNRDELVVTGTEHPTDDGTCVRDYVHVTDLIDAHVAVMRGLKNPPALYNVGTGKGVSVKEFVRACKKVTGGGFAIREVKKARPGDHAVAYADPSLIQKELGWKARYVDLEESLGHAWAWRLAHKSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNP8</accession>
    <name>C1MNP8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55985</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056684.1">
        <property type="nucleotide sequence ID" value="XM_003056638.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MNP8"/>
    <dbReference type="GeneID" id="9682586"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55985"/>
    <dbReference type="eggNOG" id="KOG2956">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KMRHNWL"/>
    <dbReference type="OrthoDB" id="514302at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024395">
        <property type="entry name" value="CLASP_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567">
        <property type="entry name" value="CLASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567:SF9">
        <property type="entry name" value="CLIP-ASSOCIATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21040">
        <property type="entry name" value="CEP104-like_TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12348">
        <property type="entry name" value="CLASP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="2">
        <location>
            <begin position="73"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="2">
        <location>
            <begin position="418"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="2">
        <location>
            <begin position="862"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="2">
        <location>
            <begin position="1233"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="707"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="662"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="741"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1482" mass="153637" checksum="DF4E81BBA300EBF0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNQ7</accession>
    <name>C1MNQ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_15588</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056688.1">
        <property type="nucleotide sequence ID" value="XM_003056642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNQ7"/>
    <dbReference type="STRING" id="564608.C1MNQ7"/>
    <dbReference type="GeneID" id="9682591"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15588"/>
    <dbReference type="eggNOG" id="KOG0531">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ERNRINM"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd21340">
        <property type="entry name" value="PPP1R42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="257" mass="28338" checksum="CF66E64943B01129" modified="2009-05-26" version="1" fragment="single">MSDAHAAPAPDAAAANPEPAEEEDDDFAHDGVRMTRDVIVKSLSRADRQREDFDAHLRRLTHLRLDGKNIGRVDALATVPGVRVLYLYDNVISRLAGLDPLAPSLTHLYLQNNNLPRVEGLAKLAKLQKLYLDGNRITYVDGLGGCAELEELHLSAQRLDPEEELEFDAQTMASLARSLRVLVASRTRVRDPRPLRALASLRVLDLSHCQIEATRDLESVLLSAKKLTSLDARGNPGLSKGPKHRRDAKLTLLGQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNQ8</accession>
    <name>C1MNQ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55994</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056689.1">
        <property type="nucleotide sequence ID" value="XM_003056643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNQ8"/>
    <dbReference type="STRING" id="564608.C1MNQ8"/>
    <dbReference type="GeneID" id="9682160"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55994"/>
    <dbReference type="eggNOG" id="ENOG502QSK6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TADCLLM"/>
    <dbReference type="OrthoDB" id="424372at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044966">
        <property type="entry name" value="RPH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36359">
        <property type="entry name" value="PROTEIN RESISTANCE TO PHYTOPHTHORA 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36359:SF1">
        <property type="entry name" value="PROTEIN RESISTANCE TO PHYTOPHTHORA 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="230" mass="24228" checksum="162442B6C4D68D9D" modified="2009-05-26" version="1">MSASVGARCALVASARVASASASASARSRSARLGRRPSASVSSSSSSRVVVVVRAESSETERAADLDKEVSKRAKKIASTFAPRSSTPAGKKNPAFKGSTLYTIFEVQAYVSLVVGSLLSYNVLLPSDEPNIARLMGMWSVWMFAVPSLRARECDAREKDALNFLFVAVPVINVLIPVVWKSFAAVFTADCLLMAYVYYDKGAGIFNDGSGGEDAPGPATEGASEGVEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNW2</accession>
    <name>C1MNW2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_56054</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056714.1">
        <property type="nucleotide sequence ID" value="XM_003056668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNW2"/>
    <dbReference type="STRING" id="564608.C1MNW2"/>
    <dbReference type="GeneID" id="9682620"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56054"/>
    <dbReference type="OMA" id="RECAFLE"/>
    <dbReference type="OrthoDB" id="435311at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028156">
        <property type="entry name" value="RIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028159">
        <property type="entry name" value="RPA_interact_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028158">
        <property type="entry name" value="RPA_interact_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31742:SF1">
        <property type="entry name" value="RPA-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31742">
        <property type="entry name" value="RPA-INTERACTING PROTEIN RPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14768">
        <property type="entry name" value="RPA_interact_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14766">
        <property type="entry name" value="RPA_interact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RPA-interacting protein N-terminal" evidence="8">
        <location>
            <begin position="7"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="RPA-interacting protein C-terminal" evidence="9">
        <location>
            <begin position="228"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="177"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="324" mass="35007" checksum="1BC5B85F94342C9A" modified="2009-05-26" version="1">MSDAAPPRRRGNKHRASGAWKAQLKEDAIERVKANRVAILSRARTGSDARGGVKEALQEILEDEISRAKRRRTNDDEGGAEDAEDAAARPSSVAGVETPSQGGDASGARVGAQGEREDDEDEDDDEMWADATPPRRSRSRSRSRNGNGATTWQETIETLSEVEYESLMLAMHASIEADLQKEEAAMLAEELERAEEEQSRELRDAADRFDAWQLDCAAAARADDPVVLCPVCKSRRLMRSSGNIFCGCGGLRLSLNASGGVVGAGGGGGEVGLALLQSRLDQCYERHGGGDCRCRELSFAVVDKFGIEALYAECRECAFLEAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP01</accession>
    <name>C1MP01_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Filamin like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FLM</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_56093</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056733.1">
        <property type="nucleotide sequence ID" value="XM_003056687.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MP01"/>
    <dbReference type="GeneID" id="9682640"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56093"/>
    <dbReference type="eggNOG" id="KOG0518">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FITTASY"/>
    <dbReference type="OrthoDB" id="264520at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044801">
        <property type="entry name" value="Filamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017868">
        <property type="entry name" value="Filamin/ABP280_repeat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001298">
        <property type="entry name" value="Filamin/ABP280_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002859">
        <property type="entry name" value="PKD/REJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38537:SF15">
        <property type="entry name" value="FILAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38537">
        <property type="entry name" value="JITTERBUG, ISOFORM N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00630">
        <property type="entry name" value="Filamin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02010">
        <property type="entry name" value="REJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00557">
        <property type="entry name" value="IG_FLMN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50194">
        <property type="entry name" value="FILAMIN_REPEAT"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="4529"/>
            <end position="4547"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="161"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="778"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="898"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="1012"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="1360"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="1557"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="1733"/>
            <end position="1866"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="1875"/>
            <end position="1973"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="1979"/>
            <end position="2092"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="2354"/>
            <end position="2477"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="2591"/>
            <end position="2693"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="3078"/>
            <end position="3171"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="2">
        <location>
            <begin position="3185"/>
            <end position="3290"/>
        </location>
    </feature>
    <feature type="domain" description="PKD/REJ-like" evidence="5">
        <location>
            <begin position="3755"/>
            <end position="4076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="82"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="4488"/>
            <end position="4524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="4554"/>
            <end position="4609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="4624"/>
            <end position="4726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="4491"/>
            <end position="4521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="4557"/>
            <end position="4572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="4573"/>
            <end position="4585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="4586"/>
            <end position="4608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="4624"/>
            <end position="4643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="4661"/>
            <end position="4671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="4704"/>
            <end position="4726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="4726" mass="480020" checksum="D1AA9858AF87EB2E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP47</accession>
    <name>C1MP47_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_697</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the DExH box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056759.1">
        <property type="nucleotide sequence ID" value="XM_003056713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP47"/>
    <dbReference type="STRING" id="564608.C1MP47"/>
    <dbReference type="GeneID" id="9682198"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_697"/>
    <dbReference type="eggNOG" id="KOG0920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HGMAEIM"/>
    <dbReference type="OrthoDB" id="496632at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000002">
        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059023">
        <property type="entry name" value="RNA_hel_CTD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF246">
        <property type="entry name" value="DEXH-BOX ATP-DEPENDENT RNA HELICASE DEXH4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26026">
        <property type="entry name" value="RNA_hel_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="21"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="297"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="803" mass="86513" checksum="7D7678F0F7B86BBC" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP91</accession>
    <name>C1MP91_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquinone biosynthesis O-methyltransferase, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-demethylubiquinol 3-O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.64</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">3-demethylubiquinone 3-O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Polyprenyldihydroxybenzoate methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.114</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">COQ3</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_56189</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">O-methyltransferase required for two non-consecutive steps during ubiquinone biosynthesis. Catalyzes the 2 O-methylation of 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid into 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid. Also catalyzes the last step of ubiquinone biosynthesis by mediating methylation of 3-demethylubiquinone into ubiquinone. Also able to mediate the methylation of 3-demethylubiquinol into ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-methionine = a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:44452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10930"/>
            <dbReference type="Rhea" id="RHEA-COMP:10931"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64694"/>
            <dbReference type="ChEBI" id="CHEBI:84443"/>
            <dbReference type="EC" id="2.1.1.114"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:44380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="2.1.1.64"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3-demethylubiquinone + S-adenosyl-L-methionine = a ubiquinone + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:81215"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:19654"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:231825"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of a multi-subunit COQ enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.64" evidence="5"/>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EC" id="2.1.1.114" evidence="5"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057245.1">
        <property type="nucleotide sequence ID" value="XM_003057199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP91"/>
    <dbReference type="STRING" id="564608.C1MP91"/>
    <dbReference type="GeneID" id="9682684"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56189"/>
    <dbReference type="eggNOG" id="KOG1270">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NEVRHFN"/>
    <dbReference type="OrthoDB" id="3265906at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061542">
        <property type="term" value="F:3-demethylubiquinol 3-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120537">
        <property type="term" value="F:3-demethylubiquinone 3-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010420">
        <property type="term" value="F:polyprenyldihydroxybenzoate methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00472">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010233">
        <property type="entry name" value="UbiG_MeTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01983">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43464">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43464:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="131"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="366" mass="38288" checksum="F8B459AB8FA67A19" modified="2009-05-26" version="1">MSSRKAASALARWALTTRSRPTTTTTTTTSAKEPRVASLASSLHRARAHNNASTSESSASTIDTVNRWETEKFERDAALWWNEREGPFAPLHAMNPARLGFIRDVLVNHFQGDVEGGIGISRANRGVEGISRAAGSGSGSASGSGSGSGSGSTRSPPSADAARDARPLAGLRVLDVGCGGGILCESLARMGADVTGIDAGKRNIDIAKKHASLDPAIDAKITYHAAPAEELLASGASFDAVLSMEVVEHVDNPETFVKSLHGLTRPGGAVVMSTLNRTARSYALAIVAAERIMGWVPPGTHEFGKFLTPEELTVLFRRAGLTLREAAGMRYTPGVPLIGGGLKGGSWSLSAGDLAVNYIVYASRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPB9</accession>
    <name>C1MPB9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56219</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057258.1">
        <property type="nucleotide sequence ID" value="XM_003057212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPB9"/>
    <dbReference type="GeneID" id="9682233"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56219"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="157"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="234" mass="26153" checksum="B91B85B52F42A303" modified="2009-05-26" version="1">MHRRRGDGGDHARDQGQVARGGGAHNNSRKGKTASRTRKGSEKCESSRSPAEKGHWEGIDEFGADGNEASRGVGTVDEAEDEERRLEDQARHLEEKLALLREEQVMVAKKHEEVRIRKAARRELENFKSELQDEFDGVVLALSEEKNAKLKVAGSFKREIKSRIAELESMLTQLGDKVSAVTDLYDATVNELQKELAEAVNEREKTLEAELRDELAGRFATLRNSGENKFVGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPK0</accession>
    <name>C1MPK0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56933</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057592.1">
        <property type="nucleotide sequence ID" value="XM_003057546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPK0"/>
    <dbReference type="GeneID" id="9683101"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56933"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="288" mass="28849" checksum="699689734A88A663" modified="2009-05-26" version="1">MLRRAAARASSWTRASARRGFASKSDGPGDASPSSVARSSSSNAPPAPASSSSSSSSSNAAARAAAAAPEASPEELIRAGKPLNLSQSAELLFDDATPRARGGRRADGTFTLDWHLWHAFLAALPAAAALAYAQHVKTTDGWKKHEEKLRGAGGDAGGALRALAGGGGGGGEGGGDASSLSSSSSSSNDDDLRRTVASLQRQVQELASRIAGDGDAGVAAEGEMTARAAATAAAAAAATSAAAGGRAATSSTSSAAGEDGATGEGNRRHLVGISREWWRRRRRRGGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPQ1</accession>
    <name>C1MPQ1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_67116</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057992.1">
        <property type="nucleotide sequence ID" value="XM_003057946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPQ1"/>
    <dbReference type="STRING" id="564608.C1MPQ1"/>
    <dbReference type="GeneID" id="9683106"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67116"/>
    <dbReference type="OMA" id="CGYVRFA"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="6">
        <location>
            <begin position="64"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="290" mass="31052" checksum="688FC8B2788F4B94" modified="2009-05-26" version="1">MRAVLALRAPATARASTPARVEKTPPAAPPPRSSRGGGVAAAVALSAAVTLASPSLAATPQTMYVAGGANVFLEKEFNDLRYAGVLDVVPGLATGVNDDGTPVEAVAVTYDADRLAKREAGRTQVTSAHEVLMRVYWKRADPTRTDGQFKENGARYRPAIWVSNAEERAEVETNARRLAASGVYGGNRGEATAAIAIPILNTPPPSFAPAPAEDFGKLAKNPKLFEKEQKTRDAAFKDLWGFVQFCADRVCGYVRFAPKCVGECLDVFPEYRERNFGVPELTGNIKITSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPQ3</accession>
    <name>C1MPQ3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic</fullName>
            <shortName evidence="9">RA</shortName>
            <shortName evidence="9">RuBisCO activase</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RA</name>
        <name evidence="12" type="ORF">MICPUCDRAFT_32785</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Plastid</location>
            <location evidence="1 9">Chloroplast stroma</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the RuBisCO activase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057993.1">
        <property type="nucleotide sequence ID" value="XM_003057947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPQ3"/>
    <dbReference type="STRING" id="564608.C1MPQ3"/>
    <dbReference type="GeneID" id="9683027"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32785"/>
    <dbReference type="eggNOG" id="KOG0651">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MVDSKFQ"/>
    <dbReference type="OrthoDB" id="2014558at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009579">
        <property type="term" value="C:thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046863">
        <property type="term" value="F:ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000258">
        <property type="entry name" value="Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044960">
        <property type="entry name" value="RCA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048571">
        <property type="entry name" value="RuBisCO_activase_AAA_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32429">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32429:SF32">
        <property type="entry name" value="RIBULOSE BISPHOSPHATE CARBOXYLASE_OXYGENASE ACTIVASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21228">
        <property type="entry name" value="RuBisCO_activase_AAA_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 9" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="10">
        <location>
            <begin position="139"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Ribulose bisphosphate carboxylase/oxygenase activase AAA helical" evidence="11">
        <location>
            <begin position="286"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU369045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="419" mass="45607" checksum="C7241103468E2308" modified="2009-05-26" version="1">MSAVTMSSMIAPVAKIGAVGKVARHQLGSVPNQLGKGNGMKVQMSRWKGMDEDISDDQQDIARGRGMVDSKFQGGFGLGGTQNAIMQGSDYVSDGFKDLSNMSDEGYYISKSYMDKITVHVAKNFMDLPKIKVPLILGIWGGKGQGKTFQSTLIFKRLGIAPIIMSAGELESGNAGEPAKLIRQRYREASDIIKKGKMSTLFINDLDAGAGRMGGSTQYTVNNQMVNATLMNLADNPTNVQLPGQYQVEEIPRVPIIATGNDFSTLYAPLIRDGRMDKFYWSPTFEDRCGVACGIFKADGVNEKDVEVLVRTFDGQSIDFFGALRARVYDQKVREWVQTVGQENIGSYLVNPSRDKGKLEFEPPVMSLEVLLQHGKALEGEQENVKRVQLADAYLDGAVLAGEGGSSNTEQSAVNSLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPS3</accession>
    <name>C1MPS3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46953</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057634.1">
        <property type="nucleotide sequence ID" value="XM_003057588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPS3"/>
    <dbReference type="GeneID" id="9683439"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46953"/>
    <dbReference type="OMA" id="WEARNQY"/>
    <dbReference type="OrthoDB" id="10690469at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="690"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="519"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="624"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="650"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="949" mass="100247" checksum="4D22EA572698B2F2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ15</accession>
    <name>C1MQ15_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">magnesium chelatase</fullName>
            <ecNumber evidence="2">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CHLH1</name>
        <name evidence="12" type="ORF">MICPUCDRAFT_26233</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>protoporphyrin IX + Mg(2+) + ATP + H2O = Mg-protoporphyrin IX + ADP + phosphate + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60492"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.6.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Porphyrin-containing compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunit H family.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057680.1">
        <property type="nucleotide sequence ID" value="XM_003057634.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MQ15"/>
    <dbReference type="GeneID" id="9683485"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26233"/>
    <dbReference type="eggNOG" id="ENOG502QT3B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WETGQAM"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10150">
        <property type="entry name" value="CobN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011771">
        <property type="entry name" value="BchH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003672">
        <property type="entry name" value="CobN/Mg_chltase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022571">
        <property type="entry name" value="Mg_chelatase_H_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02025">
        <property type="entry name" value="BchH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009140">
        <property type="entry name" value="PRK12493.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44119">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44119:SF1">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02514">
        <property type="entry name" value="CobN-Mg_chel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11965">
        <property type="entry name" value="DUF3479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Magnesium chelatase subunit H N-terminal" evidence="11">
        <location>
            <begin position="98"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="CobN/magnesium chelatase" evidence="10">
        <location>
            <begin position="262"/>
            <end position="1383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1403" mass="153945" checksum="EE5989631B4A40E8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ74</accession>
    <name>C1MQ74_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_67281</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058077.1">
        <property type="nucleotide sequence ID" value="XM_003058031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ74"/>
    <dbReference type="GeneID" id="9683147"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67281"/>
    <dbReference type="OrthoDB" id="10632503at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="153" mass="17274" checksum="262215533C2E2545" modified="2009-05-26" version="1">MTTTVEGVTNLPSPEKVEATNLLRLDEAYQGRAMFVKVKCVDGEAPSQLSHHPELRFRFPPRVRDEPPVIFNGVSIQVRGFFFRSVREISLSRRRVVYTSSPSRHIASLSERVAPSLLHASAGDGRRGNTHAPRPRRVLREHGRDLRLSLRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQM8</accession>
    <name>C1MQM8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_47070</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057787.1">
        <property type="nucleotide sequence ID" value="XM_003057741.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MQM8"/>
    <dbReference type="GeneID" id="9683591"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47070"/>
    <dbReference type="eggNOG" id="KOG1831">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IDEYHCY"/>
    <dbReference type="OrthoDB" id="1933107at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20710">
        <property type="entry name" value="NOT1_connector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000012">
        <property type="entry name" value="Ccr4-Not transcription complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.800:FF:000001">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.840:FF:000003">
        <property type="entry name" value="Transcription regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055454">
        <property type="entry name" value="CNOT1-like_NOT1_connector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25097">
        <property type="entry name" value="ARM_Cnot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="11">
        <location>
            <begin position="393"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="10">
        <location>
            <begin position="609"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="9">
        <location>
            <begin position="886"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="8">
        <location>
            <begin position="1198"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1-like NOT1 connector" evidence="12">
        <location>
            <begin position="1535"/>
            <end position="1689"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="7">
        <location>
            <begin position="1853"/>
            <end position="2211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="789"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1339"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1687"/>
            <end position="1709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="789"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="804"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="817"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1393"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1414"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1687"/>
            <end position="1707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH57738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2233" mass="235479" checksum="1713632CBF56A730" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR43</accession>
    <name>C1MR43_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57519</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058238.1">
        <property type="nucleotide sequence ID" value="XM_003058192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR43"/>
    <dbReference type="GeneID" id="9683305"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57519"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037693">
        <property type="entry name" value="CCDC15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14817">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14817:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="221"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="344" mass="37324" checksum="A5D2580404D5E0D4" modified="2009-05-26" version="1">MAAATLNVECNVPSHNVPHRVTRHASTLNAPYATTSDDVAESAFAAVERATAMKKLKEQRLRSFQDSLRRRVNETETARTSAAEQLARELTDIDLVLGDPTVANATRAPRTEPPSALELLMVSKASGVRSSHQALLNQTRPLASGGGRGGGAGGSAAVSSASGPDRVRAAKEAYASRERAAAAAAREKMKHAERAREERRLQEVAAATDFTEENNAFTAAEDRHREEAKRGSVDAEANRRRAREYAKAEAERMKRERKRESAKAKKAARYTTALQDSVRAQLARKRVTLPPLCACPHAAKSQIFDPGHVYKCAHNCPLHDDEAAYHAALSQLLSAHDVIITAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRB6</accession>
    <name>C1MRB6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57596</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shikimate kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058276.1">
        <property type="nucleotide sequence ID" value="XM_003058230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRB6"/>
    <dbReference type="GeneID" id="9683340"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57596"/>
    <dbReference type="eggNOG" id="ENOG502QS29">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KMGCRGD"/>
    <dbReference type="OrthoDB" id="515366at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21087:SF23">
        <property type="entry name" value="INACTIVE SHIKIMATE KINASE LIKE 2, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21087">
        <property type="entry name" value="SHIKIMATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="301" mass="30838" checksum="F262BD1083462C03" modified="2009-05-26" version="1">MSTVASTSATSSLARAASLASRARRAPALLRAGPGPGPGRGRRRRLRPDRAAATTTSASASATSSSDGEGGPSDASKTLRLKAEAIAKDLKGVTVTFVGDSEGANDAVGRALASALGYVPLSTPDLVEKITGQTRAEIVESDGEGGLVIAENAVFEQLSTQLRCVISTSGGGKGASARGACWDYLFGHFVIWLDDVDAAAAAAADPAAAPQREAYEFADAHLVMSTSEVKTQEEAIGIASQVVAALGELLAGDEQLAGKKTFYNKMGCRGDWPTLQPPGWDGTKEGMVDPATGKPYRDAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRB8</accession>
    <name>C1MRB8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_26583</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058277.1">
        <property type="nucleotide sequence ID" value="XM_003058231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRB8"/>
    <dbReference type="STRING" id="564608.C1MRB8"/>
    <dbReference type="GeneID" id="9683341"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26583"/>
    <dbReference type="eggNOG" id="KOG3327">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YWHQFDA"/>
    <dbReference type="OrthoDB" id="425602at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:dTMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006227">
        <property type="term" value="P:dUDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01672">
        <property type="entry name" value="TMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000679">
        <property type="entry name" value="Thymidylate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344:SF1">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate kinase-like" evidence="10">
        <location>
            <begin position="13"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH58228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="214" mass="23419" checksum="AE32BBC7EB448159" modified="2009-05-26" version="1">MASLVARGAFILFEGVDRCGKTTQSTKLVEALKSSGVNAELWRYPDRTTSMGQMINSYLQSKTEMDDGAIHLLFAANRWEKRAAMEAKLAEGVTLVVDRYSYSGVAFTAAKGIPGLDLEWCKSPEVGLLRPDAVLYLNMPVEAAAARGGFGEERYETSDLQKAVRANFDKLREDWWTIVDATGTVDEVHAACRAVADDAVAKCVAGAPYARLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRG8</accession>
    <name>C1MRG8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_47173</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058305.1">
        <property type="nucleotide sequence ID" value="XM_003058259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRG8"/>
    <dbReference type="GeneID" id="9683363"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47173"/>
    <dbReference type="OMA" id="FEMAHAM"/>
    <dbReference type="OrthoDB" id="10546673at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="164" mass="17528" checksum="36C406BDF0AA210D" modified="2009-05-26" version="1">MNAIVTSATSALSSRQINTIHLKRVARPRAPMNVATRAMTSWKLDGVGCAASRGGNGARLSGASNQNCPTHAIDVSTLCASHEGRFEMAHAMFEQEGDALYLYSTKASEHSTKDEGGGFVSDELFVDGRPAPASSWSKIKLKPGQIVNIAGVEFQLYRNVHAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRH1</accession>
    <name>C1MRH1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_57651</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057925.1">
        <property type="nucleotide sequence ID" value="XM_003057879.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MRH1"/>
    <dbReference type="GeneID" id="9683746"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57651"/>
    <dbReference type="eggNOG" id="KOG0839">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YYAEVFF"/>
    <dbReference type="OrthoDB" id="241340at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016423">
        <property type="term" value="F:tRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18091">
        <property type="entry name" value="SpoU-like_TRM3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045330">
        <property type="entry name" value="TRM3/TARBP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044748">
        <property type="entry name" value="Trm3/TARBP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12029:SF11">
        <property type="entry name" value="METHYLTRANSFERASE TARBP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12029">
        <property type="entry name" value="RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="4">
        <location>
            <begin position="1789"/>
            <end position="1930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="578"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1491"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1617"/>
            <end position="1654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="587"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1491"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1635"/>
            <end position="1645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1938" mass="204227" checksum="FC87A1CD8D8BFE0F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS02</accession>
    <name>C1MS02_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_16923</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058596.1">
        <property type="nucleotide sequence ID" value="XM_003058550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS02"/>
    <dbReference type="STRING" id="564608.C1MS02"/>
    <dbReference type="GeneID" id="9684035"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16923"/>
    <dbReference type="eggNOG" id="KOG4400">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HNKSDCT"/>
    <dbReference type="OrthoDB" id="514078at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46978">
        <property type="entry name" value="ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46978:SF1">
        <property type="entry name" value="ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="191"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="191"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="291" mass="29022" checksum="D22BB7C2886FE71F" modified="2009-05-26" version="1" fragment="single">CHLCGYLDHLARDCRRGLCFNCLKSGHQSRDCPEPRGVGRETQALCCLRCGGRGHAATDCARSFAASDVARVACYVCGEFGHLCCASQDEAAGALASAGGGGGKRKSCCRCGGMGHVDADCAQRDAARFLGELACFRCGKRGHIARECPSASGGGGGGDGGDLRDVIGNGAGGGGGRSPYGGMGVAGGGGWRGGGGGGGGWTSGAHGGGGRGAPGPPGGGWGGCVGNNGGGGGGGWGAGEGHRDQNRNRDDFAAGRSFEAAPPAPPPMPTHRRYSEDNYRRPEPPRRGGPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSD4</accession>
    <name>C1MSD4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58444</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059033.1">
        <property type="nucleotide sequence ID" value="XM_003058987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSD4"/>
    <dbReference type="GeneID" id="9684100"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58444"/>
    <dbReference type="OMA" id="RSTHYPT"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="289" mass="30922" checksum="D4A426DF697DB275" modified="2009-05-26" version="1">MHVLRASTAASASAASRPSPRTRSRAASRPPRPRGARPRDRRGREKEAIRRDAISLRAAAKNDAETRGGGGDDDAEDASIKPTNASGGGANDGAGEPTMADARRKFSETFWAGIEKNRGGVPWLRPREEEDETRGDVPDDFATTAAEANAREKKTKTKTTTTTTTTISAASSSATSDEEQGEKGEGEEPETFWRRCTLLGLAIGAWMITWGLRSTHYPTLKWLLANLGACAWDPELGWSVASEVARRLGAPALRVATGWLAMRSRWRGAAACGALSFVVPDVVAEMAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSR6</accession>
    <name>C1MSR6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_47217</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERGIC family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058372.1">
        <property type="nucleotide sequence ID" value="XM_003058326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSR6"/>
    <dbReference type="STRING" id="564608.C1MSR6"/>
    <dbReference type="GeneID" id="9684163"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47217"/>
    <dbReference type="eggNOG" id="KOG2667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IIPAVWF"/>
    <dbReference type="OrthoDB" id="270930at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF25">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="8">
        <location>
            <begin position="8"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="7">
        <location>
            <begin position="149"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="7">
        <location>
            <begin position="316"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="399" mass="43714" checksum="A56C455B5F3B333D" modified="2009-05-26" version="1">MGLAARVKLFDAYHKPERHLTKKTAAGGAVTLSSLLLMAFVFVFELRSYLATERVTTTGVDVTRDEMLAINVDVTFTSLPCQTLSLDALDASGKHDQDVGGELHKTRVDRFGRAIATYESHRENDDGVVNLITELFYGFETEGHKAHVDEIKTALSAGEGCRVHGRLKVQRVAGNFHVSVHGEDARTLRATFEHPRNVNMSHAVHRLSFGKSFPRKEDPLSGFTRTTRHANETGTYKYFLKVVPVTYTGKSSPSALKAYERKFRRESAALAIETKRKKKRLEKMRARGVEGGGGGGGGGGGGGKERWVEAKTPRGVTRTNLYSVTETYIPTKNWNGGSLPAVYFIYDLSPIAVTISDARKSFGHFLARTVAGVGGAYAIAGLIDRMIHHSLTVPPGKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSS7</accession>
    <name>C1MSS7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_57807</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058730.1">
        <property type="nucleotide sequence ID" value="XM_003058684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSS7"/>
    <dbReference type="STRING" id="564608.C1MSS7"/>
    <dbReference type="GeneID" id="9684169"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57807"/>
    <dbReference type="eggNOG" id="KOG0119">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MCERDEN"/>
    <dbReference type="OrthoDB" id="497369at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032570">
        <property type="entry name" value="SF1-HH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047086">
        <property type="entry name" value="SF1-HH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF148">
        <property type="entry name" value="CCHC-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16275">
        <property type="entry name" value="SF1-HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="533"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="8">
        <location>
            <begin position="249"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="153"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="436"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="563"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="601"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="622" mass="66080" checksum="2A520D742AD8D694" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MST3</accession>
    <name>C1MST3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_39645</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058734.1">
        <property type="nucleotide sequence ID" value="XM_003058688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MST3"/>
    <dbReference type="GeneID" id="9684173"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39645"/>
    <dbReference type="OMA" id="PMEWATA"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="762"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="827"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="602"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="762"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="782"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="829"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="865"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="901" mass="88013" checksum="D99E67320B852AE4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTJ1</accession>
    <name>C1MTJ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58091</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058872.1">
        <property type="nucleotide sequence ID" value="XM_003058826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTJ1"/>
    <dbReference type="GeneID" id="9683938"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58091"/>
    <dbReference type="OrthoDB" id="10261153at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050744">
        <property type="entry name" value="AI-2_Isomerase_LsrG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33336:SF1">
        <property type="entry name" value="(4S)-4-HYDROXY-5-PHOSPHONOOXYPENTANE-2,3-DIONE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33336">
        <property type="entry name" value="QUINOL MONOOXYGENASE YGIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="14"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="139" mass="15597" checksum="D915C45121C4FE6E" modified="2009-05-26" version="1">MSLPFKHHGLKGEIVITVKVKVAWGRVAEFLRVMREDALESRKEPGCVCFHVSALEGEREFMFYEVYKNEAAVTKHKETPHYAKWDAFRKSRDKEGVVAIESEEKVIATGVYIDAVPVLGPLVGRPCNGPLDAPGLMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTL3</accession>
    <name>C1MTL3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_39806</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058880.1">
        <property type="nucleotide sequence ID" value="XM_003058834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTL3"/>
    <dbReference type="GeneID" id="9683952"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39806"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="217" mass="23390" checksum="02D0BFFEC4F78975" modified="2009-05-26" version="1">MHAAVRNAAYKMDEAFAFDSDPTGQVGASATQQSRSPERKTTTAATSVDGRAPAAAAKKPRAGMSSTAINALRAAVDAFVARVTSPATGRKAPWPLADLVPLAVRDDAQEYLKKTKAHELRALYARVETSFETLVRFPLTKEAYGKLDRFVRAFPGCDARRREVGPEERRREGFEFARGEVHFVDVVVTAEGVAAARDVLASGAKERITGLVDTPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTS0</accession>
    <name>C1MTS0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_40045</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059071.1">
        <property type="nucleotide sequence ID" value="XM_003059025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTS0"/>
    <dbReference type="STRING" id="564608.C1MTS0"/>
    <dbReference type="GeneID" id="9684808"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40045"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ENFIMPE"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46699">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE STN8, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46699:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STN8, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="206"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="530" mass="58095" checksum="B2367E829DB44374" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTZ4</accession>
    <name>C1MTZ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_40095</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059106.1">
        <property type="nucleotide sequence ID" value="XM_003059060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTZ4"/>
    <dbReference type="STRING" id="564608.C1MTZ4"/>
    <dbReference type="GeneID" id="9684515"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40095"/>
    <dbReference type="eggNOG" id="KOG1388">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GMDETGH"/>
    <dbReference type="OrthoDB" id="505607at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11852">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11852:SF0">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="3">
        <location>
            <begin position="48"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="305" mass="32769" checksum="3E672126A8890372" modified="2009-05-26" version="1">MWQTLHATFVREARESGTAGRSRCRTLAMRGTQFGEFYDELAGRRAVFEKWFPLNEARAFGISGDRTQNVLRRIRDGELSFRHPPGVVVLCVGTNNLGRDNDGPADTFLGIRAVVLEILQTLPGTRVLLTGILPRGPAKGRSSMPPAAGEAASYADEPRGVRLDGERRKNSSPSSKYAQPGAHTAAIEEVNARLKALARGSGGVVAFVDCASAFLSDDGASIRPERMRDVLHPTAEGMHAWFQILKPAVEALRNAPAPSESWYTGASVAPASENGTLESVDGGVRLALSRCVLSHTGPHTTALAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUG4</accession>
    <name>C1MUG4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58797</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059193.1">
        <property type="nucleotide sequence ID" value="XM_003059147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUG4"/>
    <dbReference type="GeneID" id="9684633"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58797"/>
    <dbReference type="OMA" id="HEDMVES"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="631"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="683"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="513"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="521"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="557"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="716" mass="77662" checksum="38EE8AA477E6BA3F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUH0</accession>
    <name>C1MUH0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_5637</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TlyA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059196.1">
        <property type="nucleotide sequence ID" value="XM_003059150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUH0"/>
    <dbReference type="STRING" id="564608.C1MUH0"/>
    <dbReference type="GeneID" id="9684933"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5637"/>
    <dbReference type="eggNOG" id="ENOG502QRA0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VLMVKPQ"/>
    <dbReference type="OrthoDB" id="449109at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004538">
        <property type="entry name" value="Hemolysin_A/TlyA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047048">
        <property type="entry name" value="TlyA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00478">
        <property type="entry name" value="tly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32319">
        <property type="entry name" value="BACTERIAL HEMOLYSIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32319:SF0">
        <property type="entry name" value="BACTERIAL HEMOLYSIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005578">
        <property type="entry name" value="TlyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="4">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="243" mass="26562" checksum="CB2EC629C1DD3774" modified="2009-05-26" version="1" fragment="single">KSRLDELTMRAHPEHSRTVVQSWIAQGKVLVDDRPVTKAGTKLRDDVHIRITATPSKYVCRGGLKLERALEHFEMDVRGLVILDAGLRRVLTGGFADCALQAGAARVYGVDVGYGQVAERIRVDPRVVVMERTNLRHLQPLPELVDVATLDLSFISVLKVLPAVAAATKPGGTLVVLIKPQFEATRAQIGSKGVVRDASVHEEVIEKVVTGASELGWRYEGHTTSPIKGAKEGNTEFLAKFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV38</accession>
    <name>C1MV38_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_69749</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059305.1">
        <property type="nucleotide sequence ID" value="XM_003059259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV38"/>
    <dbReference type="GeneID" id="9684745"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69749"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="212" mass="22430" checksum="DAD1BC153BCC2B3A" modified="2009-05-26" version="1">MARSARARAAEGAAARRGRVPGLRRGRARGLEQRRRADGLHGGLHAVARELSRLARRRGRLRGGEVRSGARRSRVRIRRGERMRGAGHRVCRERHARVGRVSRVRRAGAVGVGRLQVSRRVVSDGGSALRPAALAALADARAAAVRGARDRGDGGEGVSRGEDHEKARAADARGDSRLLGAQSGAAVAVLVATRGAAEGSRAAGVFMIYVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVN3</accession>
    <name>C1MVN3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Geranylgeranyl diphosphate reductase, chloroplastic</fullName>
            <ecNumber evidence="2">1.3.1.83</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Geranylgeranyl reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_49640</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the reduction of geranylgeranyl diphosphate to phytyl diphosphate, providing phytol for both tocopherol and chlorophyll synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>phytyl diphosphate + 3 NADP(+) = geranylgeranyl diphosphate + 3 NADPH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:75434"/>
            <dbReference type="EC" id="1.3.1.83"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cofactor biosynthesis; tocopherol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Porphyrin-containing compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the geranylgeranyl reductase family. ChlP subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.83" evidence="2"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059782.1">
        <property type="nucleotide sequence ID" value="XM_003059736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVN3"/>
    <dbReference type="STRING" id="564608.C1MVN3"/>
    <dbReference type="GeneID" id="9685506"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49640"/>
    <dbReference type="eggNOG" id="ENOG502QQWY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MVNPFNG"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102067">
        <property type="term" value="F:geranylgeranyl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045550">
        <property type="term" value="F:geranylgeranyl reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000083">
        <property type="entry name" value="Geranylgeranyl diphosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010253">
        <property type="entry name" value="BchP_ChlP_pln/prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011774">
        <property type="entry name" value="Geranylgeranyl_Rdtase_pln/cyn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050407">
        <property type="entry name" value="Geranylgeranyl_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054715">
        <property type="entry name" value="GGR_cat"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02023">
        <property type="entry name" value="BchP-ChlP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02028">
        <property type="entry name" value="ChlP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42685">
        <property type="entry name" value="GERANYLGERANYL DIPHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42685:SF4">
        <property type="entry name" value="GERANYLGERANYL DIPHOSPHATE REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22578">
        <property type="entry name" value="GGR_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Digeranylgeranylglycerophospholipid reductase catalytic" evidence="13">
        <location>
            <begin position="141"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00058147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00067953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH55734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="380" mass="42496" checksum="52B3A48DD01DA062" modified="2009-05-26" version="1">MDNCKPCGGAIPLCMVGEFDLPEEIIDRKVTKMKMISPSNRAVDVGQTLNDKEYIGMCRREVMDDFLRKRAKSLGTNLVNGLFMKLEDPGQGNGAITIHYNDYEADSKVGEPKTMEVDCIIGADGANSRVAKNIDAGEYDYAIAFQERIKIPDEKMEYYKDLAEMYVGDDVSPDFYGWVFPKYDHVAVGTGTVVNKTAIKTYQAAMRKRAEEKCAGGKIIRVEAHPIPEHPRPRRVQGRVTLVGDAAGYVTKCSGEGIYFAAKSGRMAAEAVVERSENGTKEVDESDLRLYLDKWDRKYWATYKVLDILQKVFYRSNPAREAFVEMCADEYVQKMTFDSYLYKTVVPGNPLDDMKLLGNTVASIVRANALRAAGKSQVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVP4</accession>
    <name>C1MVP4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_59453</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060074.1">
        <property type="nucleotide sequence ID" value="XM_003060028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVP4"/>
    <dbReference type="STRING" id="564608.C1MVP4"/>
    <dbReference type="GeneID" id="9685226"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59453"/>
    <dbReference type="eggNOG" id="KOG2357">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HAHCANE"/>
    <dbReference type="OrthoDB" id="10039147at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032469">
        <property type="term" value="P:endoplasmic reticulum calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012879">
        <property type="entry name" value="CCDC47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883">
        <property type="entry name" value="ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883:SF0">
        <property type="entry name" value="PAT COMPLEX SUBUNIT CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07946">
        <property type="entry name" value="CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910522" evidence="7">
        <location>
            <begin position="26"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="385"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="426" mass="46807" checksum="FBA1EE7A8A3B4F85" modified="2009-05-26" version="1">MLRRRVWAIACALLLGVLLFAPTRASASGADWDDDDEFDAPPARASKDDASRAPLDADDASPPPSDKRASRDRAFKGKMRERYGDYPPVFEWKYELLFPLLIAGYLAFYVVGDRKNRAIVRAWEEAHARPDGVLMKNFAIVGAGPEAGAGPYKGSMFTREGPDEYRLYATGRRFVKAAVVTLKMRNRTDPFALFFRYLDSKNKTPTLPPADPHDTCVVECVMRDDAGISPGCGFAFGTTRGMAKLEKVADDVARLMSVAVVKHRDGSGPLAGTKKTSNAVVVKAESSELASDVVSDVVCELALGEAAASSTHGKHLLHAHCANEATTAEYNRLGLTGSWTIRFAFRVPKRVTADAMREAHGELLKLVPHLVDRVARVRLSGAQKELAEKRRARRREEDASKNRKENQARSVHWSPYDPVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVZ2</accession>
    <name>C1MVZ2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59563</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059836.1">
        <property type="nucleotide sequence ID" value="XM_003059790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVZ2"/>
    <dbReference type="GeneID" id="9685561"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59563"/>
    <dbReference type="eggNOG" id="ENOG502RZCC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="549039at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="573" mass="64245" checksum="CF87F25A6BA331E3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW21</accession>
    <name>C1MW21_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_9447</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. CPYC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059849.1">
        <property type="nucleotide sequence ID" value="XM_003059803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW21"/>
    <dbReference type="STRING" id="564608.C1MW21"/>
    <dbReference type="GeneID" id="9685288"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9447"/>
    <dbReference type="eggNOG" id="KOG1752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KPGHLEC"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000093">
        <property type="entry name" value="Glutaredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="2">
        <location>
            <begin position="4"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="89" mass="9651" checksum="30CE9F4794790710" modified="2009-05-26" version="1" fragment="single">SNAVTVWSKSWCPFCTQVKQLLEKEGASYLAIELDKFHEAEEIQASLAATTGQRTVPNVFVGGKHVGGCDDTMALHRSGELRKMIEAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW30</accession>
    <name>C1MW30_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chloroplast envelope protein translocase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TOC75</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_47751</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Chloroplast outer membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059853.1">
        <property type="nucleotide sequence ID" value="XM_003059807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW30"/>
    <dbReference type="STRING" id="564608.C1MW30"/>
    <dbReference type="GeneID" id="9685582"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47751"/>
    <dbReference type="eggNOG" id="ENOG502QTZ3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THAFAFW"/>
    <dbReference type="OrthoDB" id="1161695at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009707">
        <property type="term" value="C:chloroplast outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045037">
        <property type="term" value="P:protein import into chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.310">
        <property type="entry name" value="membrane protein fhac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057355">
        <property type="entry name" value="POTRA2_Toc75"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF42">
        <property type="entry name" value="BACTERIAL SURFACE ANTIGEN (D15) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25280">
        <property type="entry name" value="POTRA2_Toc75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="1" id="KW-1002">Plastid outer membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="7" id="KW-0946">Virion</keyword>
    <feature type="domain" description="Toc75-like second POTRA" evidence="6">
        <location>
            <begin position="226"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="5">
        <location>
            <begin position="410"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="519"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="743" mass="78615" checksum="1F5CC0998CE49562" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX05</accession>
    <name>C1MX05_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49636</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059722.1">
        <property type="nucleotide sequence ID" value="XM_003059676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX05"/>
    <dbReference type="STRING" id="564608.C1MX05"/>
    <dbReference type="GeneID" id="9685451"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49636"/>
    <dbReference type="OMA" id="LYAKWVW"/>
    <dbReference type="OrthoDB" id="495463at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19358">
        <property type="entry name" value="TenA_E_Spr0628-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiaminase-2/PQQC" evidence="1">
        <location>
            <begin position="54"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="257" mass="28434" checksum="6CE81B431EE9BED9" modified="2009-05-26" version="1">MSTSRWFDAIDSSTPFHAEVWSHADAQTVRDSAAWDDLAANAIRRAPSEAFASRFKTYFVSDYVFVEDFIDLLARALASSRDFEHKKVLGAFLHLILQGEASIFRRSMKKLWGVDADAIKRDPTSAGALAIASTDVPRRMSAFLRRVADDGDHLARVAVIAVAEALYLHWGKRVTTNYVIAVSLGVGADGVADDRELYATWCYPLHASDEFEACVCAFVEAFNASWRDAGEESREACRGVVAEMLELEVEFTALLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXX7</accession>
    <name>C1MXX7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_60325</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060775.1">
        <property type="nucleotide sequence ID" value="XM_003060729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXX7"/>
    <dbReference type="GeneID" id="9685906"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60325"/>
    <dbReference type="eggNOG" id="KOG1444">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YAYCKLQ"/>
    <dbReference type="OrthoDB" id="417037at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="242" mass="25416" checksum="2CA39D6DE6107182" modified="2009-05-26" version="1">MFRRVAPLSCAYFAYVALSMSSVRGVNLPMYTTLRRTTAAFTMTAEYFAVGKRQSRAVTTAVGAMVAGAFVAALGDAHFDASGAFNTLVPIRPRYARVFANNAATAVYLACISRYGKSSGLNSFGMMWCNGVVTAPAVLASTMATGELAAVGTFRRLGEFSFEAVVVASCALAFALNYAVFLNTSLNSALTQTICGNLKDVVVIVLGFNAFGGVAVNAVNACGVAVGLCASFRYATLKFKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXX8</accession>
    <name>C1MXX8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41060</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060776.1">
        <property type="nucleotide sequence ID" value="XM_003060730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXX8"/>
    <dbReference type="STRING" id="564608.C1MXX8"/>
    <dbReference type="GeneID" id="9686213"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41060"/>
    <dbReference type="OrthoDB" id="10265389at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="137" mass="15099" checksum="E93E25FF2B1993A3" modified="2009-05-26" version="1">MMHAASAAGASSAVAFPPRRPPRRGASPLDEPFKPAKLHKLLVALAYTTLSVLLLFFNKALLSSFDFPCANVITLAQLCFSNALLYGLRRGRYVAFVDDVSLVPRDCVDKRTGFPTIKARPIHWSPYDRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYD6</accession>
    <name>C1MYD6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59874</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060555.1">
        <property type="nucleotide sequence ID" value="XM_003060509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYD6"/>
    <dbReference type="GeneID" id="9685705"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59874"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="64" mass="6265" checksum="347D59B2B01D537D" modified="2009-05-26" version="1">MARTADVGAAASKLCAAARRRREYGGLAPDDISVIVLDVGEKRSGGGGGCFACLRGGGGAAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYE9</accession>
    <name>C1MYE9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_18871</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060562.1">
        <property type="nucleotide sequence ID" value="XM_003060516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYE9"/>
    <dbReference type="GeneID" id="9685725"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18871"/>
    <dbReference type="eggNOG" id="ENOG502QSMF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SHKWRAK"/>
    <dbReference type="OrthoDB" id="189024at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="3">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="3">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="185" mass="20262" checksum="6F0D53F5D5C230D0" modified="2009-05-26" version="1" fragment="single">KDALLDAIATVERGVTATEADKEAIDALAVTLERLNPNARALSCNLLNGEWELLYTTSASIIGANKPWPFRPLGPIYQTIDVPRLRAANRETFPFFNAVDADLTPTSAAAVDVQFVKFKLFGGLIRVDAPAAARGALSVTYLDEEIRVSRGDRGNLFVLRMHDATKELPRKGDDDDEEEKGVYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYK2</accession>
    <name>C1MYK2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_34483</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060581.1">
        <property type="nucleotide sequence ID" value="XM_003060535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYK2"/>
    <dbReference type="STRING" id="564608.C1MYK2"/>
    <dbReference type="MEROPS" id="M48.021"/>
    <dbReference type="GeneID" id="9685737"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34483"/>
    <dbReference type="eggNOG" id="ENOG502QUG6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PNAMCIG"/>
    <dbReference type="OrthoDB" id="272500at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07325">
        <property type="entry name" value="M48_Ste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.10:FF:000007">
        <property type="entry name" value="Peptidase M48 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10120">
        <property type="entry name" value="CAAX PRENYL PROTEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M48" evidence="8">
        <location>
            <begin position="159"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="377" mass="40486" checksum="38106FCF40B141C6" modified="2009-05-26" version="1">MSALLASSAAPRARVAPRASAVSNRGVARRASVAPRDPRPRLNDDDGRVVLRRNDVRARASAASSATPSSFPSSPWPRSASHDDDDDDAAASRRRNNVVRKKVAARDFRHPLDQQNTSLLEAIPGLSNITKSIVTPVAEQMLIMEQISTSVLVGPNQLPSVHQLVIDAAEVLDVKPPALYIRQSSQPNAYTLAISGAFYTLPVVVVHTALVELMSPAELRAVIAHELGHLKCDHGVWLTVANLLTLGAEITPLVPSFVAANFNDELMRWVRAAELSCDRAALLVAGDPSVVVSVLMKLSGGCPKLSGQLNVDAFLDQARGYDEATASPLGWYLRNAQNKQLTHPLPVARAREIDKWARDGGYRSLGIAPAAAAPEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYN0</accession>
    <name>C1MYN0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_5979</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060596.1">
        <property type="nucleotide sequence ID" value="XM_003060550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYN0"/>
    <dbReference type="STRING" id="564608.C1MYN0"/>
    <dbReference type="GeneID" id="9685742"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5979"/>
    <dbReference type="eggNOG" id="KOG0735">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MVIRAAI"/>
    <dbReference type="OrthoDB" id="498033at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000149">
        <property type="entry name" value="Nuclear valosin-containing protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF12">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="32"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="218" mass="22624" checksum="5C09C8B4BEF34943" modified="2009-05-26" version="1" fragment="single">VGGLARAKAALEEALSFPTRHARVFGAAPLRLRTGVLLYGPPGCGKTLLARAAIASAGLRVVVVKGPELLNKYIGQSEAGVRATFRRAAAAAPCALFFDEFDAIAPRRGHDSTGVTDRVVNQLLTELDGVEALVGVTVIGATSRPDLVDPALLRPGRLDRLVRVPFPDREERRAILAAVARDLAVTETGGGGGGVGESKGFTGADLRALVSDASMHAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYP3</accession>
    <name>C1MYP3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein ELF4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ELF4</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_59974</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EARLY FLOWERING 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060310.1">
        <property type="nucleotide sequence ID" value="XM_003060264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYP3"/>
    <dbReference type="STRING" id="564608.C1MYP3"/>
    <dbReference type="GeneID" id="9686040"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59974"/>
    <dbReference type="eggNOG" id="ENOG502S43Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1895690at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042753">
        <property type="term" value="P:positive regulation of circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048511">
        <property type="term" value="P:rhythmic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040462">
        <property type="entry name" value="EARLY_FLOWERING_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009741">
        <property type="entry name" value="EARLY_FLOWERING_4_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33469">
        <property type="entry name" value="PROTEIN ELF4-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33469:SF16">
        <property type="entry name" value="PROTEIN ELF4-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07011">
        <property type="entry name" value="Elf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0090">Biological rhythms</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein EARLY FLOWERING 4" evidence="5">
        <location>
            <begin position="31"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="105" mass="11175" checksum="05CDCAE07358D1B2" modified="2009-05-26" version="1">MGNEHPAITAAGLSEANELLAQLPANLWPGSEKFKVVQGLLDRNNTLINEINHNHYGRYPDGLEKNADLIKELSGNIASVISLYEEVNSGFVSLVGGTAATTEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ06</accession>
    <name>C1MZ06_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">G2-like myb-family transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_60557</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061130.1">
        <property type="nucleotide sequence ID" value="XM_003061084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ06"/>
    <dbReference type="STRING" id="564608.C1MZ06"/>
    <dbReference type="GeneID" id="9686315"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60557"/>
    <dbReference type="eggNOG" id="ENOG502RIEW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CSESTME"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000007">
        <property type="entry name" value="Two-component response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044841">
        <property type="entry name" value="LUX/BOA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31442:SF29">
        <property type="entry name" value="HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31442">
        <property type="entry name" value="HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="258"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="75"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="315"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="437"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="466"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="483"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="532" mass="53286" checksum="FFB2EB7BD2882614" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ08</accession>
    <name>C1MZ08_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63256</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061131.1">
        <property type="nucleotide sequence ID" value="XM_003061085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ08"/>
    <dbReference type="GeneID" id="9686316"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63256"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="193" mass="22369" checksum="D70C3A2EF5B30C25" modified="2009-05-26" version="1">MEREERQFSDFRARAEDERRRELENQERMKQRSASLYESKRATERREATGRGVRAEERGGKVAAQFAKNAEKLRAVKAARDVEEDGSGRAARAHRLHGNKPNPCRTPVLELVGDAFHRVADGGTKKFKGARALLHQRGRARGRAGRVRSGSLSRRWFRREEAGDEERRRKSEAAMRDARCDARPRRHERRRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0G6</accession>
    <name>C1N0G6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_10976</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061386.1">
        <property type="nucleotide sequence ID" value="XM_003061340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0G6"/>
    <dbReference type="STRING" id="564608.C1N0G6"/>
    <dbReference type="GeneID" id="9687076"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_10976"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HYAARDR"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="209" mass="22600" checksum="C8029510D240E555" modified="2009-05-26" version="1" fragment="single">KVCVITGANTGLGFIAAKEIAKKPGYKVVMACRDATRAANAAKTIAEEIPGADVDASLTLDLASLSSVERFAAAFDEKYGRLDVLMNNAGVMALPNRETTEDGLEMQMGVNHHGHFALTSRLMPTVLRTPGRKRIVNVSSVAHEWGHIDFDNINSDGFFGYLGAYHLTLLSNLYFTYELHRRLRAMPPGSGGDLVDVNAVHPGVVDTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0I9</accession>
    <name>C1N0I9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_51037</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061648.1">
        <property type="nucleotide sequence ID" value="XM_003061602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0I9"/>
    <dbReference type="STRING" id="564608.C1N0I9"/>
    <dbReference type="GeneID" id="9686837"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51037"/>
    <dbReference type="eggNOG" id="ENOG502RZCC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EKESIHF"/>
    <dbReference type="OrthoDB" id="530303at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="410" mass="45039" checksum="5BF034D27C0B9903" modified="2009-05-26" version="1">MSLLERFFEDASDVFDTHVLPRLDSGDLAVLATVNRKMRDVVFESPVDHDVRDVAAVRRELARVPNFVGSVARLAWAKEWGCPWAKETFTCIARGGNVEVARWAKERGCPWDEDTCADAAEGGHLKMLQWFRSNGAPWDTWTCTFAAEGGHLEVLQWARAIGCPSNELTCASAARGGHLEVLQWARANDCPWDMRTCSSAAGGGHLEVLQWARTNGCPWDGETCSEAALGGHLEVLQWARANDAPWDEFTCASAAEGGHLEVLQWARANGAPWDKYTCFDAASGGHLEVLQWARANGAPCNEFTCAYAARGGHLEVLQWARANGCPWDEFTCAYAAGGGYLEVLQWARANGAPWDEETCRDAAEGGHLEVLQWARAIGAPWDPMLCKARARNHMHEDVVRWISAEVGEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0J7</accession>
    <name>C1N0J7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41560</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061652.1">
        <property type="nucleotide sequence ID" value="XM_003061606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0J7"/>
    <dbReference type="GeneID" id="9687091"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41560"/>
    <dbReference type="OrthoDB" id="503507at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="647" mass="71880" checksum="0748A04341F66704" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0N7</accession>
    <name>C1N0N7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_35248</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061419.1">
        <property type="nucleotide sequence ID" value="XM_003061373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0N7"/>
    <dbReference type="STRING" id="564608.C1N0N7"/>
    <dbReference type="GeneID" id="9686859"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35248"/>
    <dbReference type="eggNOG" id="ENOG502QUAP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NAIDPPD"/>
    <dbReference type="OrthoDB" id="195057at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06160">
        <property type="entry name" value="S2P-M50_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044838">
        <property type="entry name" value="EGY1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31412">
        <property type="entry name" value="ZINC METALLOPROTEASE EGY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31412:SF0">
        <property type="entry name" value="ZINC METALLOPROTEASE EGY1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="369"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M50" evidence="15">
        <location>
            <begin position="203"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH54049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="445" mass="46419" checksum="013C807D7DE3E9B4" modified="2009-05-26" version="1">MSKEDVKRLKDEVFGYNTFYVTGTSELGEELGVSEGVLVKGNLRADRAEVWKTVQENVERVYEGKYTVFMLEEPPADFFGDDDDGGSGAGASMSGSYDASDPTNTRGPRISFLIVPASKAGPNPRTSAFQYVVAIALFGLTAGSALQLGLVAEVSRLPQATMDWLAAGSQGIDTSLAPGELPPGLDGFDSAAYIAGAVPIAGGIYASAAAHEIGHWIAAATKKIKLSIPYPIPNGQLGTFGSITQIKSLPENRTDLYDVSVAGPIGGFTVASALFFYGLALSAGGGDPNELLPIPNELFQGSLMLGAISEAILGGTADQVKGVAVHPLFIAGWCGLVTQALNCLPVGQIDGGRITQTAFGRRALGATSLGVYLGLSLGVIGSSISLPWALFILICQRTPEFAPKDDVTEVSPERQNFALLLIFVSLMILLPGADFSGLASDPLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0S8</accession>
    <name>C1N0S8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_48248</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061444.1">
        <property type="nucleotide sequence ID" value="XM_003061398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0S8"/>
    <dbReference type="GeneID" id="9687130"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48248"/>
    <dbReference type="eggNOG" id="KOG1216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CDGEEWK"/>
    <dbReference type="OrthoDB" id="1909330at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044837">
        <property type="entry name" value="REM16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31391">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN OS11G0197600-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31391:SF151">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN REM19-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="147"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="40"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="355"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="591"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="522"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="591"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="639"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="778" mass="81801" checksum="58B4D655E6358995" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1E1</accession>
    <name>C1N1E1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_51367</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061800.1">
        <property type="nucleotide sequence ID" value="XM_003061754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1E1"/>
    <dbReference type="STRING" id="564608.C1N1E1"/>
    <dbReference type="GeneID" id="9686988"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51367"/>
    <dbReference type="eggNOG" id="ENOG502SEA2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HAEVWEN"/>
    <dbReference type="OrthoDB" id="4822at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12323:SF0">
        <property type="entry name" value="CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12323">
        <property type="entry name" value="SR-RELATED CTD ASSOCIATED FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00648">
        <property type="entry name" value="SWAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SURP motif" evidence="3">
        <location>
            <begin position="217"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="360"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="389" mass="40669" checksum="FB275ECF442320E0" modified="2009-05-26" version="1">MGGGDVWNALRGQVVHTGKHAEVWENMDKFDRGRREAADAAARGGGDRGSDRGGREGGGSASADGNVGGYRKVRGPDGQMMSGAQMRNARNAEGTVDWKEKFSNDTRFSSAIGSTRSKKDKVVDIDKMAAAAKAYAAAQRAKAEAEGCGGGDGGEDAGGRGDVAAGEKRKRDGGDDGRERATIMTTTNSTILTDASGATEDRPPFALKPDDPALLKRVQKVAEFVVKNGKKFEDVTREKQRDNRVEFSFLWPGGEGVDYYAWLKHCLKNGMNPETPPGVEGGGGFDAAKLAEAARRIAEAAAATESGGGRNAAQAAVTNANVDDDAKRASAAKTKTKTSAVVAAAAAAAPVPVVAKVGAWQAVKDAEGKTYYWNKDTGATTWDPPPGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1W8</accession>
    <name>C1N1W8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51762</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061984.1">
        <property type="nucleotide sequence ID" value="XM_003061938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1W8"/>
    <dbReference type="STRING" id="564608.C1N1W8"/>
    <dbReference type="GeneID" id="9687632"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51762"/>
    <dbReference type="eggNOG" id="KOG2731">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6614653at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035516">
        <property type="term" value="F:broad specificity oxidative DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035515">
        <property type="term" value="F:oxidative RNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035513">
        <property type="term" value="P:oxidative RNA demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004574">
        <property type="entry name" value="Alkb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557:SF11">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="272" mass="30265" checksum="8B0802BFC6B887E2" modified="2009-05-26" version="1">MYAADDADDDGHRTAFRIAEKKCAPRRASRRFSSRLVSSRRVASRRVASAPSLRPTRRRRISRSSPRLITCHLARALRASSSSSSVARRYKLHREQTFRTDAKGRRRGRLARLVTRPVDLDDVVDLRDASSSSALVRRVSDDDGVTEYFTMPETHPGCVLVPNALDLDAQREWLRAAATTMHEPPARTNHGAARGSFSGLWDAAATGDRWLRDREAREGRSEGSEGSAGMEKETDAWETLDPAPTKGDPRCATSASHLLRKLRWATVGAPYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2B5</accession>
    <name>C1N2B5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51920</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062058.1">
        <property type="nucleotide sequence ID" value="XM_003062012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2B5"/>
    <dbReference type="STRING" id="564608.C1N2B5"/>
    <dbReference type="GeneID" id="9687705"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51920"/>
    <dbReference type="eggNOG" id="KOG0922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MAMEYFH"/>
    <dbReference type="OrthoDB" id="498561at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043489">
        <property type="term" value="P:RNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15838">
        <property type="entry name" value="NUCLEOLAR PROTEIN OF 40 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15838:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="38"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="171"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="432" mass="45796" checksum="0DEC82BB1DF6B60E" modified="2009-05-26" version="1">MRTVPPPPPPPPGGGGLAGRARRDDRAPLPDEEPPAVGAILRGRVASVRPFGIFVRMDGFRRDGLVHCTHVGEELTFRREDSDDAKVMAMEYFHPKDASVWVKVIDVHRDGYTGGNVKIALSMKLVDQADGKDLDPDGAQLAELARGGGGGGGGGGGGSSNAWSDDPPELNSTHRATVREVKPYGVFVQMEGYRKNGLVPTHQVSDFLEFAREDADEEKVRGIEGVIGRGESCWVKVVEIKGGGYANDPVKVTCSLKLADQSTGEDLDPQGTRYYPQGEGRDGGGTGAFYTLVPIRPRGRGAPLGARAGENVKKGGVVDWGHHAGDVRGQMDGKSYDLVVDDGIDALAAETRFDGRGPGGAPIPPPPPGPAAAAAAAAGGTIGSVEEALAILREHKKRSKKEKKHKKDSKKHKKDSKKRKKDKGGDWSSSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2N1</accession>
    <name>C1N2N1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_21167</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062115.1">
        <property type="nucleotide sequence ID" value="XM_003062069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2N1"/>
    <dbReference type="STRING" id="564608.C1N2N1"/>
    <dbReference type="GeneID" id="9687554"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21167"/>
    <dbReference type="eggNOG" id="KOG1213">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PYHTITL"/>
    <dbReference type="OrthoDB" id="10071381at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039781">
        <property type="entry name" value="Rad21/Rec8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006910">
        <property type="entry name" value="Rad21_Rec8_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585:SF69">
        <property type="entry name" value="FI11703P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585">
        <property type="entry name" value="SCC1 / RAD21 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04825">
        <property type="entry name" value="Rad21_Rec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="118" mass="13212" checksum="EC71CF7928C3FA90" modified="2009-05-26" version="1" fragment="single">MFYSQYILAKRGPLGTIWIAAHLDRRLRKQQITETDIAEAVQSIVNPEAPLALRLSGQLMLGVVRIYNRKVSYLFQDCSEALVKIKGAFAKERADLPEGGAVAVHNVITLPENYDDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2Q0</accession>
    <name>C1N2Q0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamyl-tRNA(Gln) amidotransferase subunit A, chloroplastic/mitochondrial</fullName>
            <shortName evidence="5">Glu-AdT subunit A</shortName>
            <ecNumber evidence="5">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GATA</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_21214</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast stroma</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">This protein may be expected to contain an N-terminal transit peptide but none has been predicted.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="5"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061913.1">
        <property type="nucleotide sequence ID" value="XM_003061867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2Q0"/>
    <dbReference type="STRING" id="564608.C1N2Q0"/>
    <dbReference type="GeneID" id="9687353"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21214"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EYDACEV"/>
    <dbReference type="OrthoDB" id="498685at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF7">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="6">
        <location>
            <begin position="46"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="602" mass="60055" checksum="92BF8E8DD942D69C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2Y5</accession>
    <name>C1N2Y5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_29097</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062286.1">
        <property type="nucleotide sequence ID" value="XM_003062240.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N2Y5"/>
    <dbReference type="GeneID" id="9687955"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29097"/>
    <dbReference type="eggNOG" id="KOG1896">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PMTKFKL"/>
    <dbReference type="OrthoDB" id="6109at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="5">
        <location>
            <begin position="97"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="6">
        <location>
            <begin position="575"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="4">
        <location>
            <begin position="1094"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="763"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1401"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="778"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1469" mass="154698" checksum="77934134003E8D19" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N333</accession>
    <name>C1N333_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52017</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062311.1">
        <property type="nucleotide sequence ID" value="XM_003062265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N333"/>
    <dbReference type="STRING" id="564608.C1N333"/>
    <dbReference type="GeneID" id="9687751"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52017"/>
    <dbReference type="eggNOG" id="ENOG502QPX1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NRSGSYM"/>
    <dbReference type="OrthoDB" id="514292at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009187">
        <property type="term" value="P:cyclic nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012386">
        <property type="entry name" value="Cyclic-nucl_3Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28141">
        <property type="entry name" value="2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28141:SF1">
        <property type="entry name" value="2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13563">
        <property type="entry name" value="2_5_RNA_ligase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="LigT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="257" mass="27618" checksum="CD35BBBC5C4C3D8F" modified="2009-05-26" version="1">MAATSLYSVWLEPPTDLRIKAANFIDGQVACSPGCPSFAPHVTLAGGFRGSESDARARTAALASALVAPGAPFADGVASLRAKDVATGTRYHQCVYLRMEPTETLAAAHAAAARAFDLEPGNGNGEPYVPHLSLVYGETREEIKADAADAATEALFCGVLRGFETREIVLWRTDVEDLTCESWARVERFPLVPEGGGNGGESSEEKTTAQRIIDEAEEEKKMKKMKKKKKKNPMRWLKKRLGLVKGGGGDPARTRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3P3</accession>
    <name>C1N3P3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_44827</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062409.1">
        <property type="nucleotide sequence ID" value="XM_003062363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3P3"/>
    <dbReference type="STRING" id="564608.C1N3P3"/>
    <dbReference type="GeneID" id="9688090"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44827"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="315" mass="34427" checksum="5775C1EE6ECB495A" modified="2009-05-26" version="1">MGGARVVLACRDAAAGDAAARAMTAEVEASRDVALEGEEATPPDVRTEVLDLASFASTRAFAARLVTRKISVHVLIHNAGIMPSPFALTENGHERAFHVNALGPFLLTRLLLRSTLRFARGTTRTDPCRVVFVTSAVHRFSYPERVRFERLSGDAARVKYDPVKSYAQSKLCQIVLAREFHARYRASRRARDAHVAFFAVHPGAVITEGSERARTFAVVSLRPPLAGFNPRPRRLSTPLLTPMNSTPKTAAAGAATTAYCATSRRAAGSGYYVNCNLAIPGAAAMDERLQRKVWDLATRLCEREEEEEEEEAMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N420</accession>
    <name>C1N420_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_7360</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062717.1">
        <property type="nucleotide sequence ID" value="XM_003062671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N420"/>
    <dbReference type="STRING" id="564608.C1N420"/>
    <dbReference type="GeneID" id="9687909"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7360"/>
    <dbReference type="eggNOG" id="ENOG502RXKE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EAQCNWV"/>
    <dbReference type="OrthoDB" id="5862at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021855">
        <property type="entry name" value="PAM68-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34575">
        <property type="entry name" value="PROTEIN PAM68, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34575:SF1">
        <property type="entry name" value="PROTEIN PAM68, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11947">
        <property type="entry name" value="DUF3464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="122" mass="13107" checksum="001385BF671A4DB4" modified="2009-05-26" version="1" fragment="single">EDATKRDAKREEYRSAQAKGIPQVVTDRMLKRISIFSGVPLLLGFSTGPIFYGAKVFAHLDVAPWQFFLASTLTFGGALVGITYGVLSASWEPGREGTFWGGAEIKVNVPILMATVLGKASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4R4</accession>
    <name>C1N4R4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_52654</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062837.1">
        <property type="nucleotide sequence ID" value="XM_003062791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4R4"/>
    <dbReference type="STRING" id="564608.C1N4R4"/>
    <dbReference type="GeneID" id="9688483"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52654"/>
    <dbReference type="OMA" id="TDWISIL"/>
    <dbReference type="OrthoDB" id="608866at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052450">
        <property type="entry name" value="TRBD-Containing_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734:SF1">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1 TERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="674"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="234"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="366"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="525"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="759" mass="81149" checksum="A784D4068757EC38" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4X3</accession>
    <name>C1N4X3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42505</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062868.1">
        <property type="nucleotide sequence ID" value="XM_003062822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4X3"/>
    <dbReference type="GeneID" id="9688511"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42505"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="472" mass="49271" checksum="491D12D6CABCF799" modified="2009-05-26" version="1">MPATRARDGRPDQPPATTFLADAKPGKKDRVRFAELVRLESATIRGGARDDGCVTSPRRFDERRDRDPAKDSPRVVAAAAGDDDAADAVATVAAAATEGAEPKDAAGGKKPVGVFSACKKFVTKTASYAGEKDRDAPRASSIAVPATPSAKKATTSRRAAARLLACASETLPGGPSRGARAGSPPPPARRRPRRASESVGGAVSGGPSRASTRPTLRPAAAAVVDVAAEEEEEVEEEEEEEEEEGDGSGFGPEAPPWVERDGADAVNLYVSGATSISAALLAIDETHRTPARTRESKTGRRAAPLSKQSSSEALAPRDDTSARKSPPSLLTPRNPGDHPAGDVKSSMPTWTSDAAAPARRVDDGAGGARAERATPPLPPPAPAEDDLDIGVAAGGMHDDRDFLRILMENEIIENESEDSGSDLRDTAPPFDTLEDVVADVDVGGYFATRDVVFDPPGYDFAMMHLLETAAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N596</accession>
    <name>C1N596_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52859</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063132.1">
        <property type="nucleotide sequence ID" value="XM_003063086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N596"/>
    <dbReference type="GeneID" id="9688370"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52859"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="157" mass="16210" checksum="60FE74E613C8BD18" modified="2009-05-26" version="1">MSTTRVGDAAAAAAPEPASSGLDGDRGGERRTWGDAKPKKKSGGGMFSFLKTTTKKKKSASGRSTSTTTTTTTTTMPPPSPRRGDDADADADADATAAKTSAARPPPSPIARSVASDSAASRASSGSERWGGRQQHHQVRSIHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5E2</accession>
    <name>C1N5E2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48890</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063541.1">
        <property type="nucleotide sequence ID" value="XM_003063495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5E2"/>
    <dbReference type="GeneID" id="9688980"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48890"/>
    <dbReference type="eggNOG" id="ENOG502RZPE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LWFRAFF"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF33">
        <property type="entry name" value="PEPTIDASE S54 RHOMBOID DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="369" mass="40315" checksum="F87EBD8838BD9E31" modified="2009-05-26" version="1">MPAPPPVAASSSSLLLSRVLALDPIALLACALFLMGVYFALVLAAGSSPLARIVLFKTSLFARSVRHLALSREKSGWPKTRPDPDVVVADVALSPPREKRVIFVRHGESTWNEVFNRGFGPGFPLRLAWGLLHEAAVIFSRGSFFVDAPLSHRGYRQARELRAFLKTYEPTGDGTTTNPDAAALRGDVRSILVGSNLRRAVATIAIGFWDRIARTREKIIVHSALQEMARNVDAYAIARRGEAVPLDGVEAKIGGGETMDQIPSCDARNNEGNKKVDRCGNDALLEFAAWVVENTKDADCVIVGGHSLWFKEFFKAFLPRRSDHVAKKKKIVNCGCVGFTLQAGRDDDGRVAYRIDPKSVDVIYGGFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N623</accession>
    <name>C1N623_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">CorA metal ion transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_48841</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063260.1">
        <property type="nucleotide sequence ID" value="XM_003063214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N623"/>
    <dbReference type="STRING" id="564608.C1N623"/>
    <dbReference type="GeneID" id="9688700"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48841"/>
    <dbReference type="OrthoDB" id="165352at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="470" mass="53176" checksum="DE344ECEAD6CB469" modified="2009-05-26" version="1">MSDGDATIEIADDAPAAQTITRSPSARASQSQRRSSRKGLASSRVSERVRGNSRKALMVNDVKHQTKSETRKLERFEQMQLEYFSTRDADVEQTPTPEMHYTVYRNDGGAGTTTTTKNNADSMNLLSKIGKETRKENTIRWLHFNGMNEMMMNYVCDALKLGASAVGGEMDTTKCVFHRHKDAAVRHFDSHVYVSMQLIDREECDGDIPLVSDEQVSFIYHPEKAIVISVCEDVDEESDFTALTRLLVEGESRCNVDGAHPGILLAMMADKFVDDAYPVAEELGDYLEVLSQAMVARESISFSQPVDKVRMQLWRMRRFAIRVRRLCEAYEEDALGVFDDESFKEYVGKVSKQADGLESVCEMYIGRCLSILQRVEVYQEQRTNETLFLLTIVTTLMVPVEFLTGMWGMNFVNMPDLETSWGYFMFLALIPFLMGTSYILLKVNGYLDDSPLDWSCGLGGLFKSKEGKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6E4</accession>
    <name>C1N6E4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_53256</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063323.1">
        <property type="nucleotide sequence ID" value="XM_003063277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6E4"/>
    <dbReference type="GeneID" id="9688763"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53256"/>
    <dbReference type="OrthoDB" id="194386at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF130">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="271" mass="29873" checksum="7DBA948181D44804" modified="2009-05-26" version="1">MELGAGVGVVGVVLARCMRDYTRACTTVEGDTERQPARSRRLTLTLQEKDDDAVANLTGNLRRNGVARRRAETTLVGHDMLSDRECRTAAAAGDEGRYSYDGDDDAGVDVRVVKFDWECRTNDEALRETKPDLARSVIAADVCYDPALFPGLLATLRALSSDRAALQDTESEASSRGYEPPFALIVTTLRQPETLETFVREATSAGFDVSDVSDASDVFMEEGSETEVDETRAETLGGRVGFARLPRESRDASYGEMRVHALRARRRRRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N775</accession>
    <name>C1N775_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53582</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063687.1">
        <property type="nucleotide sequence ID" value="XM_003063641.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9689128"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53582"/>
    <dbReference type="eggNOG" id="ENOG502SB78">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TWEEWIL"/>
    <dbReference type="OrthoDB" id="552790at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019902">
        <property type="term" value="F:phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052270">
        <property type="entry name" value="CACF_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22028:SF9">
        <property type="entry name" value="SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22028">
        <property type="entry name" value="SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1290"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1358"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1294"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1426"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1437"/>
            <end position="1452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1499" mass="168198" checksum="D842F5AB7654054A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N776</accession>
    <name>C1N776_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53583</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063688.1">
        <property type="nucleotide sequence ID" value="XM_003063642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N776"/>
    <dbReference type="GeneID" id="9689129"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53583"/>
    <dbReference type="eggNOG" id="ENOG502S2YM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DIGRICE"/>
    <dbReference type="OrthoDB" id="9989223at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47485">
        <property type="entry name" value="THYLAKOID LUMENAL 17.4 KDA PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47485:SF1">
        <property type="entry name" value="THYLAKOID LUMENAL 17.4 KDA PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13576">
        <property type="entry name" value="Pentapeptide_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="264" mass="27016" checksum="EEE607EE41C434DC" modified="2009-05-26" version="1">MLATLPRVSARPRVGSNPSATSRARVTAARASSSSSSRRRVGDVDVVDGRRLVDSDAASSPPSRVVSSVLGAVASASLALALSACPGPALAEAGQKPPPVRDMPGGCTIEALDLFKDTRAKFSLEVGTGALPEAILDLGGCDYSGADLDGKVLSGAIMSGANFEGAIFTGGEASRAKAVGTNFRGSVLRGTNFYEMSFAGADLRGADFDNAILTNARFGRDGGGNWAQLDGVNWEGALLSSSDAQRACENPTVDDYGRAILGCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7S6</accession>
    <name>C1N7S6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">dCMP deaminase</fullName>
            <ecNumber evidence="7">3.5.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">dCMP deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_53811</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.12" evidence="7"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064143.1">
        <property type="nucleotide sequence ID" value="XM_003064097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7S6"/>
    <dbReference type="STRING" id="564608.C1N7S6"/>
    <dbReference type="GeneID" id="9689402"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53811"/>
    <dbReference type="eggNOG" id="KOG3127">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6710946at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000021">
        <property type="entry name" value="Deoxycytidylate deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086:SF18">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="10">
        <location>
            <begin position="134"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="32"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="284"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="316"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH51765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="371" mass="39000" checksum="A97A1ADA38E5959A" modified="2009-05-26" version="1">MAGVNVAFVAIASALAGAKLQDIMKSLLDRRADADADADADADGDRRTKKKIPISPSSSSPPRTPSKAPTVASLRSPRELDPPKPPAPSSSSSSELSVVCPRCDAPATPPLSRRGVGKKKPDPFSAEGRRDYLSWDDYFMSVAFLSAQRSKDPNKQVGAVIVGADKVISGVGYNGFPRGCSDRSLPWAKRSPTDDPMETKYAYVCHAEMNAIMNKNSQSLNGATMYVTMYPCNECSKLIIQSGITEVVYFEGKLAIDAAAGDNAAATSDSSSSLSALPENVRGDAATDAAAGATPAPSTPLGKENEAGKESSSGAADKRKNVREEEEKISTPTKGGMQANPTYAAASKLLALAKVVVRQHTPRAVVDVSYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8M4</accession>
    <name>C1N8M4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translation initiation factor SUI1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_37644</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probably involved in translation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SUI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064292.1">
        <property type="nucleotide sequence ID" value="XM_003064246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8M4"/>
    <dbReference type="STRING" id="564608.C1N8M4"/>
    <dbReference type="GeneID" id="9689551"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37644"/>
    <dbReference type="eggNOG" id="KOG1770">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GQDYIHI"/>
    <dbReference type="OrthoDB" id="10248435at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11566">
        <property type="entry name" value="eIF1_SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005874">
        <property type="entry name" value="SUI1_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10388">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="5">
        <location>
            <begin position="41"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="123" mass="13651" checksum="1C648896444A7FC2" modified="2009-05-26" version="1">MTDALDSLGPQFDFADDLGGESGQKAKQDSSNAQDVQSNYIHIRTQQRNGRKSLTTLQGINPKINKKVILKECKKKFNCNGTIVDDPDLGQIIQLQGDQRKVVAQFLIDEKIAKKDVIKIHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8T9</accession>
    <name>C1N8T9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_23440</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064330.1">
        <property type="nucleotide sequence ID" value="XM_003064284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8T9"/>
    <dbReference type="GeneID" id="9689949"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23440"/>
    <dbReference type="eggNOG" id="KOG1676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HITIDQN"/>
    <dbReference type="OrthoDB" id="498599at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="8"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="90"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="156" mass="15919" checksum="1CC12CC726BFA320" modified="2009-05-26" version="1" fragment="single">MHAHPPTDAACNFIDCPPGLVGRVIGKGGETIKGLQAQSGAHITIDQNYPDGAPRKISISGPAGCVDIASKLVEDLLKGGPVRGGGVGPGQAQQIVECPKDMVGRVIGRGGETIKGLQSQTGARIQIDQSVSPCLITITGNPYCVDAASRAVVDVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8V3</accession>
    <name>C1N8V3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_54252</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064337.1">
        <property type="nucleotide sequence ID" value="XM_003064291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8V3"/>
    <dbReference type="STRING" id="564608.C1N8V3"/>
    <dbReference type="GeneID" id="9689778"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54252"/>
    <dbReference type="eggNOG" id="ENOG502QUR6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10266693at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30222">
        <property type="entry name" value="SPERMIDINE/PUTRESCINE-BINDING PERIPLASMIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30222:SF17">
        <property type="entry name" value="SPERMIDINE_PUTRESCINE-BINDING PERIPLASMIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="647" mass="68629" checksum="0F58B04C196133E9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8Z3</accession>
    <name>C1N8Z3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54298</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064526.1">
        <property type="nucleotide sequence ID" value="XM_003064480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8Z3"/>
    <dbReference type="GeneID" id="9689807"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54298"/>
    <dbReference type="OMA" id="RIACYFD"/>
    <dbReference type="OrthoDB" id="10561968at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="195" mass="22013" checksum="3650419F71F68B41" modified="2009-05-26" version="1">MVKTRIACYFDIPGPDNKPHGANFVDVREFAPPRRRASSLDARSTCVSPEVPRPPTSSRDRRPPTPPLPPPPHRSVRDPSQVDMRETDSKNELKKRVARKVGIPFYRLKMRLGPFNDVMMFDKESYPTLKVGSCAVSVACVDERLSGDQNTACNYFGAADHELPEFQDGTKKFEPHPFANWHQTWDDVEKFGATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9K3</accession>
    <name>C1N9K3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_23416</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064301.1">
        <property type="nucleotide sequence ID" value="XM_003064255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9K3"/>
    <dbReference type="STRING" id="564608.C1N9K3"/>
    <dbReference type="GeneID" id="9689908"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23416"/>
    <dbReference type="eggNOG" id="KOG2590">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MPFIANF"/>
    <dbReference type="OrthoDB" id="340227at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07323">
        <property type="entry name" value="LAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF132">
        <property type="entry name" value="LA-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="4">
        <location>
            <begin position="26"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="102" mass="10664" checksum="8E2A34E2D49D722E" modified="2009-05-26" version="1" fragment="single">MFFPPGVHGFGGGGRGGGGGGGGGSTVGCERILAAVRAQVEYYFSVENLCKDVFLRERMDDEGYIPMPFIANFNRIRMMTPEPSVVLEAISGSAAVEVTGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAG5</accession>
    <name>C1NAG5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_66058</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064955.1">
        <property type="nucleotide sequence ID" value="XM_003064909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAG5"/>
    <dbReference type="GeneID" id="9690396"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66058"/>
    <dbReference type="eggNOG" id="ENOG502SBHM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10656400at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912415" evidence="1">
        <location>
            <begin position="30"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="2">
        <location>
            <begin position="216"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH50935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="386" mass="44510" checksum="82339DE8E159374C" modified="2009-05-26" version="1">MSRSRFQLLKLATCFLFVSLLSIPRLTQSFGREILPMLHSTIMTCDSNSCDISEACVANNRTLFVIGSASVPIVERALLSVRLRRNGSVALNVRALDISILTTSRRRSKAFLIERYVDNNCGHILGDEVWPAFRMMQKYAPNSDRLGHESDLYVDRPSRPRCDDYFDALVKNGEVFDLNLKTEVESRIICYDHVYFGMSGFSYVDEDLAYLSSPVFSADAKAFRNKFYMKYPSKEKENPDKLVIMEKRSGDHLTNIDNINELKLAAARTFKELDVLIACLEDYSVGNQVELMSRTKMLISLPGSDVMNAIFMQDDSTLLVYCRFVNGVKENSNEIRLWFRYLVHLRVFEFCSEFPDVRLEDNRNVWINVTRLNDTKYEQRLIPHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAL0</accession>
    <name>C1NAL0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_66113</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. CMP-Sialate:CMP antiporter (TC 2.A.7.12) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064925.1">
        <property type="nucleotide sequence ID" value="XM_003064879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAL0"/>
    <dbReference type="GeneID" id="9690422"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66113"/>
    <dbReference type="eggNOG" id="KOG2234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KCYVIAS"/>
    <dbReference type="OrthoDB" id="498253at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH50905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="313" mass="33786" checksum="24ED5AB0BB58441E" modified="2009-05-26" version="1">MSVVPSIVALVALVVQNTALVFAMKLAFRDTAKSFHVSVVVLCAEAFKFCVCCAISIFTRKSPGMTFKYLTRIFDHRMALPSLLYVVQNNILFVAVQHLTPTVYVACSQTKVLATVFFSVTFLNVKLTIRQIVAVFLLTAAMISLQLPESTPVSDANLVGKKSSQVTGFAAVFCSSGISGFASVYMERLLKARDGDFTLFEQNIQLGLFSLPLALLAGLLQDFQLYKTTGFFHGFDVVIYSVIFLQAVGGLIVAAVVKFASSIMKCYAISASICLVAIVSCSLGIETMSSNALAGICLTVTSVHLFTKRSLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGZ7</accession>
    <name>C1MGZ7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_61182</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054865.1">
        <property type="nucleotide sequence ID" value="XM_003054819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGZ7"/>
    <dbReference type="STRING" id="564608.C1MGZ7"/>
    <dbReference type="GeneID" id="9680355"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61182"/>
    <dbReference type="eggNOG" id="KOG2946">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IKQTDIQ"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF1">
        <property type="entry name" value="PROTEIN YIPF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="7">
        <location>
            <begin position="73"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="224" mass="23784" checksum="C032E403AA64742F" modified="2009-05-26" version="1">MSNGSFGQAAPSSGGGGGTFSDDVDRLFSAAEVREGGLAGARDDLDWNTLDESVWRTLKRDVDRVASNTLLVLNPMRVARDPTRPMREWDLWGPLVFVLLLGVCLSHGDGDDASTVFSVVFATVAFGAVALTMNVLLLGGHIIFLQAISLLGYCLVPLNVAVFLMFISENVVWRTLLVCGAVAWSSWASVPFVSAAVPAARRALAVYPVILFLISLGVLAAVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH74</accession>
    <name>C1MH74_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_50075</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054903.1">
        <property type="nucleotide sequence ID" value="XM_003054857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH74"/>
    <dbReference type="STRING" id="564608.C1MH74"/>
    <dbReference type="GeneID" id="9680452"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50075"/>
    <dbReference type="OrthoDB" id="38730at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044:SF3">
        <property type="entry name" value="KETOPANTOATE REDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044">
        <property type="entry name" value="NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="376" mass="39566" checksum="D1AF32197C67A81B" modified="2009-05-26" version="1">MASRACLRWVAPPTATRRERRRCDQRSRRVARRAAAATADAADDAAAARDDGDDGGRHDFTTVFGRGRVASVLARALGISRCVLVGRYNSFPADDIGGPIYVATHASDLAAVLAKVPASRRRDVVLMQGGLLRRAWLEARGAADATQVALFLSARRDGDVVDGGGRTVACGPHAAHVVETLARVGVRCAEVDATEFGTAATEKLLWASIFWLMCATRGGAGGDAVTVGEIVNDVDASARAEALAVELMRVVVAAGELDGGADAAEDGTSTVAGSPPAPALPLLDAEALEYEGTGFGTDAEFEQGLIVIGLFRYCDDIPDAAPSAEMATREGAFRNGWFLAAAERYALETPLHERLLRDAGVDVDELRSRARAEHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHM3</accession>
    <name>C1MHM3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_50252</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054980.1">
        <property type="nucleotide sequence ID" value="XM_003054934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHM3"/>
    <dbReference type="GeneID" id="9680701"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50252"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="133" mass="14830" checksum="5561BD7454DF81B4" modified="2009-05-26" version="1">MTRARRLRGAQKPVAAYSHFRVLHVFPFHSRLSFPLSQGSDTSAVERSKRFGRGCRGHALWRGCDGVGMVKGPDGSTRHVFAGATIAPLWCNSCVSSRTDGQMRRKETFNLGGKFAENVLYTNELTFKILINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHR1</accession>
    <name>C1MHR1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Bromodomain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_50291</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054997.1">
        <property type="nucleotide sequence ID" value="XM_003054951.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MHR1"/>
    <dbReference type="GeneID" id="9680912"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50291"/>
    <dbReference type="eggNOG" id="KOG0386">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1525">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RRKCFEI"/>
    <dbReference type="OrthoDB" id="200660at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.390.10">
        <property type="entry name" value="SAND domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037382">
        <property type="entry name" value="Rsc/polybromo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010919">
        <property type="entry name" value="SAND-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062:SF19">
        <property type="entry name" value="PROTEIN POLYBROMO-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062">
        <property type="entry name" value="SWI/SNF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="11">
        <location>
            <begin position="1001"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="11">
        <location>
            <begin position="1390"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="103"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="399"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="697"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1166"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1293"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="629"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="701"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1187"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="1206"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1226"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1293"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1333"/>
            <end position="1346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH60249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1645" mass="180907" checksum="9058A539D5352BD8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHV1</accession>
    <name>C1MHV1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histone deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_50331</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055019.1">
        <property type="nucleotide sequence ID" value="XM_003054973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHV1"/>
    <dbReference type="STRING" id="564608.C1MHV1"/>
    <dbReference type="GeneID" id="9681123"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50331"/>
    <dbReference type="eggNOG" id="KOG2683">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RRHYWAR"/>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF10">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="4">
        <location>
            <begin position="101"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="395" mass="43060" checksum="93D9B066D399DD7D" modified="2009-05-26" version="1">MAHLCPRYPQRAMFLAAARGRARVRRMSAARAALAVPEPHRGGATTRSEDARRENVDVATASNNVVPFRRKLPETVPDAPPASAEEVNIAAPAISPRERSIEPSLPSVRALASFITAAERLLVITGAGCSTESAIPDYRSPKGAYSTGFKPMTHQDFLRADGNRKRYWARSFVGWKKFAEGTSPNRAHVALAALQREGHVWRLITQNVDRLHHAAGSEDALELHGTTHEVICLNCDDVTPRTRMQRRLIELNPTFLGSTLRDAEDVVKRQNPDGDVELDGGVEKTFKLPTCLKCGTGTLKPKVVFFGDCVPAKDASVAKAWSERADAVLVVGSSVSTFSAYKLVKEAVTRGAPVAILTNGDTRVDDVADLKVRAVAGETLSRILDVVRREETYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIW8</accession>
    <name>C1MIW8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_50725</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055206.1">
        <property type="nucleotide sequence ID" value="XM_003055160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIW8"/>
    <dbReference type="STRING" id="564608.C1MIW8"/>
    <dbReference type="GeneID" id="9680311"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50725"/>
    <dbReference type="eggNOG" id="KOG1343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PANYCAR"/>
    <dbReference type="OrthoDB" id="424012at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF17">
        <property type="entry name" value="HISTONE DEACETYLASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="7">
        <location>
            <begin position="89"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="438" mass="47504" checksum="64603D40A576A5FF" modified="2009-05-26" version="1">MRGLVWTAGDGVTSVTSPGTSSSMPKDAYNDPLARKRAILRALFGGDERLRGGAIRHRAKAGNLQLRHVDDDLDEPPGIADFRRAASYCHDRGMLRYLETAWERWAATPEEERCRFFRRATSAASDASSSTPTPSDAIPALVPANYCARHDAITRPGANLHSQTCYYHTDDDTPIFEGLLGQLVADATVAVACAAHVVVQRERLARFDRTLNDDPVDAFYHYACVNHPGHHAGKSTMGGYCYVNNAAMIARVIQEHHTLRNPDRAKPVNVAILDVDYHAGNGTASIFWEDPTVFVASIHADPNGDYPWNACFEDDVGGGDGEGFTRCAPLPRRAGWDVYEPALAGSLDAIKAQRPFALIVSLGLDAHADDPVQEKATAGMELTVDDYFNVGRMIRETADAVDATVVFVQEGGYQVEVAGELVRTVFKGFEAGGVSIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK08</accession>
    <name>C1MK08_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64153</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055911.1">
        <property type="nucleotide sequence ID" value="XM_003055865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK08"/>
    <dbReference type="GeneID" id="9681659"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64153"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="465" mass="51744" checksum="5A4254F2BC7DA071" modified="2009-05-26" version="1">MGSNYTPRFVQSGIRVLYARTYQKRKQSQTGRLFVDVAETLLKRVLNDMNKKVKGRGAEIFNIDPQELFQIIEDLDIGDVQYQDRRKSERIGKRLLWLVTDALSGKEKLVFAEDYDEVLKQYALTNERDSMDERSKYITRYFIRPVNPWKAVQRVLRPQQVMSISTHSETETFEDNDEVDQESVAPSPFSDGFRTPRIPEEVPRTPEEVPRTPEEGIARALKDVGLVAETKGIRGLLPPDAVRGGRHECMKTVDISITGLDSRVTRTLGDVVVPHPFSGDGRAKFNGRRPTATRSPANIQPGEYTLEAEKKKLDWYGNIPEGRGFSLVPMAIDTYGFKAPRFRKFLNQLADHGARGTVPAGDAASEAAAEATLSAIARSKSYWKRHIMGHISVALVSAIGDRVAGAPISYALRTSRDSENFHAGAAAQILFMEPDTAGDFHIAPAPCAREAHMGSMNPVVGLLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKH0</accession>
    <name>C1MKH0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histone deacetylase interacting domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_70276</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055996.1">
        <property type="nucleotide sequence ID" value="XM_003055950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKH0"/>
    <dbReference type="STRING" id="564608.C1MKH0"/>
    <dbReference type="GeneID" id="9681697"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70276"/>
    <dbReference type="eggNOG" id="KOG4204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GLCRDAH"/>
    <dbReference type="OrthoDB" id="10265969at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000001">
        <property type="entry name" value="Paired amphipathic helix protein Sin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000002">
        <property type="entry name" value="Paired amphipathic helix protein SIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000003">
        <property type="entry name" value="Paired amphipathic helix SIN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="9">
        <location>
            <begin position="369"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1169"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1169"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1193"/>
            <end position="1209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1209" mass="137752" checksum="14B96CE10BC281B5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKY2</accession>
    <name>C1MKY2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_64700</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAP30 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056076.1">
        <property type="nucleotide sequence ID" value="XM_003056030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKY2"/>
    <dbReference type="STRING" id="564608.C1MKY2"/>
    <dbReference type="GeneID" id="9681989"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64700"/>
    <dbReference type="eggNOG" id="ENOG502SBNP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="510958at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024145">
        <property type="entry name" value="His_deAcase_SAP30/SAP30L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038291">
        <property type="entry name" value="SAP30_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025718">
        <property type="entry name" value="SAP30_Sin3-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13286:SF22">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13286">
        <property type="entry name" value="SAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13867">
        <property type="entry name" value="SAP30_Sin3_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase complex subunit SAP30 Sin3 binding" evidence="8">
        <location>
            <begin position="42"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="127" mass="14248" checksum="62BDC3C02B3934C2" modified="2009-05-26" version="1">MSRTLNTDGNRGSSSDADKNVAFHLPGTFSRNEQVRVDLTKLEAPSLRKYRRVFKLGEVQQGGTKDELIPAVVRHWKQTIVDEDETLIAFVTALRQRAKRGNIQAVNNRHSSFKTNSTRSGPRGKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML04</accession>
    <name>C1ML04_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64730</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056088.1">
        <property type="nucleotide sequence ID" value="XM_003056042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML04"/>
    <dbReference type="GeneID" id="9681546"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64730"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="344" mass="37728" checksum="F89E02A010D86B2C" modified="2009-05-26" version="1">MSDDLVRRRGTSGRTRTVSSPRACGSTLTPAPASAVTRTRRRLPASPSAVARTQPLPIARRGRSRRTRERHDRGGRGSRRSCSARLRLRTVNVPPVSPCSERRLRGSGGFSAGVVDPYRAIAEVPSASTHWRGCHRSDRDGTNGVRRRSIAGDRGERRVAGHSVITYECLSTTPTPSGSAIISRPLPAVLDDEDAGNVAVARMEASHGLESAFRRLSAHGADLRAKATLLRARRRRRDLSTARHVPSQRSGGRPPPPPPPPPPIASSCEALRQLRTHDVPTTRPRGDARGARIHARMTSPATSFDSLVRLASPRHAAATAARRRRRRRGREWRRWPKNFHVSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLB8</accession>
    <name>C1MLB8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_13817</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056535.1">
        <property type="nucleotide sequence ID" value="XM_003056489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLB8"/>
    <dbReference type="STRING" id="564608.C1MLB8"/>
    <dbReference type="GeneID" id="9681779"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13817"/>
    <dbReference type="eggNOG" id="KOG1980">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CHITEPI"/>
    <dbReference type="OrthoDB" id="119302at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF1">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome biogenesis protein BMS1/TSR1 C-terminal" evidence="1">
        <location>
            <begin position="76"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="380" mass="42598" checksum="9199685A2B786783" modified="2009-05-26" version="1">MICKSEEERDRSILLEQTAHFGGDEFTSSQHVAADEFQPQVQLSFQTRESAVTIQHSKTRQSSRAGASDEHFFPDEIETPIDIPARLRFARYRGLKSFRSSLWDTNEQLPVDYERIFTFKNFKRATLLASTEARSQASSGLGIGTFVKLIIRGIPSVAARGLLAGPSWSGWCGGAGPFVISTLMQHESKLTVMHYGITKTPSCDFPLRSKTPLWFHIGFRRERASPIFSSDGIGDKHKFERFLQHGRPSIASVFGPVVYPPAPVLAFSEKSFASGMPAQLVLSGSVREAAPNRVILKRIVITGVPHKTHKSKAVVRQMFFNPEDVLWFKPLELWTKYGMRGKIKDAVGTHGSMKCQFNGVIQQRDTVCASLYKRVFPKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLN8</accession>
    <name>C1MLN8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_70784</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056599.1">
        <property type="nucleotide sequence ID" value="XM_003056553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLN8"/>
    <dbReference type="STRING" id="564608.C1MLN8"/>
    <dbReference type="GeneID" id="9681854"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70784"/>
    <dbReference type="OrthoDB" id="495795at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34276">
        <property type="entry name" value="MINI-RIBONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34276:SF1">
        <property type="entry name" value="MINI-RIBONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="2">
        <location>
            <begin position="116"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="288" mass="32574" checksum="4D447D8D10B87813" modified="2009-05-26" version="1">MCEKVFFPPHIIVKQTTYWSNGDGAANPRHLSINQVFLHSRRVLLAFRGCRRSRPSTRRLVETEAKKKPQKKGARSKQPKKRASWECSMKAKRTAGDLVPIPVKIIDRGPDVALAYTYLGDAVWELYARQHMILRSAEKAGRTSPCGTVIRPQEATKLNWCSSVAMSDHLARLLADGTITDDEISILEWGRNFGHESRSGHKTLQHREASSLEALIAYWYLFDQDRLHLVLSHLGMILCRQPVSQLTSVQVKVTMSNVRHGRVGTTYDNLGTHYNFKSGQYCDVSEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLU3</accession>
    <name>C1MLU3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_56270</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the importin alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057280.1">
        <property type="nucleotide sequence ID" value="XM_003057234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLU3"/>
    <dbReference type="STRING" id="564608.C1MLU3"/>
    <dbReference type="GeneID" id="9682263"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56270"/>
    <dbReference type="eggNOG" id="KOG0166">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="REQIQCV"/>
    <dbReference type="OrthoDB" id="29145at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000040">
        <property type="entry name" value="Importin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.690">
        <property type="entry name" value="Importin-alpha, importin-beta-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032413">
        <property type="entry name" value="Arm_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002652">
        <property type="entry name" value="Importin-a_IBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036975">
        <property type="entry name" value="Importin-a_IBB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024931">
        <property type="entry name" value="Importin_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16186">
        <property type="entry name" value="Arm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01749">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005673">
        <property type="entry name" value="Importin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51214">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IBB" evidence="9">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="116"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="159"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="243"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="327"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="532" mass="58551" checksum="C3C5D5D8ECB5A23B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLY7</accession>
    <name>C1MLY7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino Acid/Auxin permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_49511</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056845.1">
        <property type="nucleotide sequence ID" value="XM_003056799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLY7"/>
    <dbReference type="STRING" id="564608.C1MLY7"/>
    <dbReference type="GeneID" id="9682742"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49511"/>
    <dbReference type="OMA" id="MTYISIA"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF461">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="35"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="446" mass="47253" checksum="8B2600E0A28F40A0" modified="2009-05-26" version="1">MSGTAPKQHERSPLLAKDGTILPLDAPHSKRRNVHWFGLAFIILGEIAGQGTFTLPKQMSRLGWVLGTITCLGFVGLNALSLRVMHAMSTRVEGEGFTRTGDVATRLLGERGGKIARVVVQLYLFSLIAADLNAMGRSVMNFCFHTRVCMPVASALAVAMALPFAQLRAYGDITFIASLSLLALALCVLLLVFADDAGAHIVKTSTSLSPSNDVADVLTGIGGFFFAAGGGQCAFFEYLSEMETPADYLKTVSTTAPTLIALYYGTASYVYSKYGTGAPGFLLDILPFDGHRYAGNALFVFHLIVSFVILNAALLRGFVTRDVTDKSWSARAEWATMSVVVLGAAYVLCNSVNLIENLVGAIGALFQPVIVMCLPATYALVAMKGERGKRAESVRVALKCMIALGALLVPLLTAGALRTTIADAKDVAAPFSCGVCVTKACAAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM66</accession>
    <name>C1MM66_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46756</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057347.1">
        <property type="nucleotide sequence ID" value="XM_003057301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM66"/>
    <dbReference type="STRING" id="564608.C1MM66"/>
    <dbReference type="GeneID" id="9682786"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46756"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044781">
        <property type="entry name" value="At5g10690-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47581">
        <property type="entry name" value="OS09G0431600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47581:SF2">
        <property type="entry name" value="OS09G0431600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="651"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="785"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="962"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="658"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="789"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1164" mass="122476" checksum="2FF5A9D0F97506D8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMI9</accession>
    <name>C1MMI9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56545</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057414.1">
        <property type="nucleotide sequence ID" value="XM_003057368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMI9"/>
    <dbReference type="STRING" id="564608.C1MMI9"/>
    <dbReference type="GeneID" id="9682375"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56545"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CCVGREQ"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19101">
        <property type="entry name" value="AKR_unchar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43147:SF5">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43147">
        <property type="entry name" value="PROTEIN TAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="115"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="440" mass="47091" checksum="2F128DDF3E8221CD" modified="2009-05-26" version="1">MSSFTAPPTATSSTTTTEGRALRRSRKPPRAARRGHAVVVKASNEEPPAAPAELSRRDVFAATAALAAAIPLDRASAPFAVPAAFAAMETAGSIPAKVPAAASPLKFSTSTPSRVIKGCWQLGGGHRGDQATDRTSGAAAVEDFAAFARAGINTFDTGPEACGYGPSELIIGEALKSGTIKREDVNIYTKLCCVGREQQNMTSDWVNQKLDLPCRRLGTNKLDLVQMYWNEYNAKHYVDAALFLTDAKAAGRIGAVGLTNFDTKRVAEMVDAGAEIASNQIQFSLLDRRPEREMVPYCAKNGIALLPYGVVAGGLLSDKFLDFPGEDVVLDTSSKRKYASVLGYAGGYAWYQRLLAELRRVGDKHGGATIANVASRWVLDSNDVTPAIILGARNANHVDDHRAMFAFELDDDDKASIRGVLNKGKAPSADCYTYERGGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MML3</accession>
    <name>C1MML3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56574</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056948.1">
        <property type="nucleotide sequence ID" value="XM_003056902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MML3"/>
    <dbReference type="STRING" id="564608.C1MML3"/>
    <dbReference type="GeneID" id="9682865"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56574"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="657"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="867"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="326"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="408"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="490"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="546"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="886" mass="92021" checksum="7D52808373EE3ED1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMU7</accession>
    <name>C1MMU7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyltransferase</fullName>
            <ecNumber evidence="14">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_46839</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="14"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056991.1">
        <property type="nucleotide sequence ID" value="XM_003056945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMU7"/>
    <dbReference type="STRING" id="564608.C1MMU7"/>
    <dbReference type="GeneID" id="9682906"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46839"/>
    <dbReference type="eggNOG" id="KOG0831">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GIMRRIF"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH58636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="488" mass="53790" checksum="B816EB32396071A4" modified="2009-05-26" version="1">MADADGAAKPRPGLTNRKNAAAAAAATTTTTTTTAPPDSPEPRSMSRTPSFTSDVIDGGFAYRTCDSGSASSLASLAEDEVAKFVKPDRKPEKIPHKATGLLFWTMVMYAWYQILGLLFIPIGVYFAVLASPAFSPSAKFDSHAAQVGIVVMIYAFLVSALIICPVYFVVCAHPYVRLAFVGYVSWYALVDAKTPMNGGRFLPWFRRLPFWATMADYFPVRLHKSVDLDPKGNYLFGYHPHGIIGVGALITFATNATGFEQAFPGLDLRLLTLASNFYLPFTREILLAMGINSVKKESVETNLTRRPGASVAIVVGGAAEALDARPGWAVLTLARRKGFVKLAMKTGASLVPVFAFGENDIFDQVDNPDGSPLRRFQTWTKQLIGVTPPAFYGRSLSRGIMRRIFRSGAGVMPKRESIEVVVGHPIKCPKMAEPSVKQIDEYHQKYISALKELYDTHRRLFHKLKREGSEDDLAARMKRMQSLRFIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN83</accession>
    <name>C1MN83_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein arginine methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_14868</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057534.1">
        <property type="nucleotide sequence ID" value="XM_003057488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN83"/>
    <dbReference type="STRING" id="564608.C1MN83"/>
    <dbReference type="GeneID" id="9682499"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14868"/>
    <dbReference type="eggNOG" id="KOG1499">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HENMVRD"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF89">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="6">
        <location>
            <begin position="153"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="377" mass="39972" checksum="BFCCA444C95CD8A3" modified="2009-05-26" version="1">MLDDVPRTRAYRVALEKNPTLTAGATVLDVGCGTGILSMFAARGGAASVVGVDGAAAIADVARANVRDNGLSDKVTIVHGKLEELLREEEEEEGEGAGGRLLRAAAADGSTSKFDVLVSEWMGYGLLYESMLDTVIAARDALLKPGGAVLPDVATIHVAGFGRNATSLPFWDDVYGFRMPEVQSRLIQDAARSGFAVVCPVKGEHVVTSSAEVQRLDLATMTVKDTEFTSSECVLTARGDGVRGDEEDACHGVVMWFDTEFSARFCVDAPTTLSTSPYEEKTHWAQAMLHFPEPIFLHPDGCLATTGGGGGGGSESESESDLGGEARPAHGVKVRLGMAKCDAARNDHRALDVSLEWVPVDADGNEGGKRRARIYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNB3</accession>
    <name>C1MNB3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_45420</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057074.1">
        <property type="nucleotide sequence ID" value="XM_003057028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNB3"/>
    <dbReference type="STRING" id="564608.C1MNB3"/>
    <dbReference type="GeneID" id="9682989"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45420"/>
    <dbReference type="eggNOG" id="KOG0057">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="XDAVLFH"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18582">
        <property type="entry name" value="ABC_6TM_ATM1_ABCB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000221">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF402">
        <property type="entry name" value="IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="294"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH58719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="542" mass="58287" checksum="6A1D895F7D5C3D83" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNF5</accession>
    <name>C1MNF5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_61932</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056642.1">
        <property type="nucleotide sequence ID" value="XM_003056596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNF5"/>
    <dbReference type="STRING" id="564608.C1MNF5"/>
    <dbReference type="GeneID" id="9682535"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61932"/>
    <dbReference type="eggNOG" id="KOG4174">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498773at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF26">
        <property type="entry name" value="FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="2">
        <location>
            <begin position="97"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="386" mass="42182" checksum="C67C8A2556010E31" modified="2009-05-26" version="1">MHAVRSRCFAALRASARRATSATSRLSRRRPHHRANASRRARPTRRDVSSATTTRETGEDASRGGRFLTASPTEEGPDDRRRRHRAPHALPAFGDVLLLGEGDFSFSRALVESASVGVGRVTATSLESAAEIETRWGGAANVDALRRASNVEIVHGVDATALETTLPDPGGRRYDKIVFMFPHIAGKGRISLNRELLDAFFQSAERALAPGGSIEVGLVKGQGGTPADEDKQRALGNTWQIQARAAGGDFVLVDAARFDAASWEALGYRSRGHWRSARRGEGEDVEEGGGVRTALKRADFARDRRRGFQHRDGVVHLFRRETELGGATCPWPVEYARDVSVFVDPNVFSDEEFARVARASAGRGVESGAFYRLCVRAFFTHRSVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNU2</accession>
    <name>C1MNU2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_8179</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057171.1">
        <property type="nucleotide sequence ID" value="XM_003057125.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNU2"/>
    <dbReference type="STRING" id="564608.C1MNU2"/>
    <dbReference type="GeneID" id="9682153"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8179"/>
    <dbReference type="eggNOG" id="KOG2241">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KVWKHEE"/>
    <dbReference type="OrthoDB" id="19141at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="4">
        <location>
            <begin position="4"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="165" mass="17874" checksum="53F08B6FCC3B03DB" modified="2009-05-26" version="1" fragment="single">KAIDVSVLDIRVGTIVKAWEHPGADKLWVESVELGEERPRQIVSGLRAFKTEAQMTGARVLVLCNVKKGPLREELSEGMVMCASNADHTEVDFIVPPEGVPNGEKVAFEGFDGEPVDVLTPKKKMFEQCAEKLSTDADGVAKYDGVPFMTSKGPCVSTLKNAAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPC6</accession>
    <name>C1MPC6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="3 10">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_46678</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>deamido-NAD(+) + L-glutamine + ATP + H2O = L-glutamate + AMP + diphosphate + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="3 10"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056798.1">
        <property type="nucleotide sequence ID" value="XM_003056752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPC6"/>
    <dbReference type="STRING" id="564608.C1MPC6"/>
    <dbReference type="GeneID" id="9682700"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46678"/>
    <dbReference type="eggNOG" id="KOG2303">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TSQEVCN"/>
    <dbReference type="OrthoDB" id="2020662at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07570">
        <property type="entry name" value="GAT_Gln-NAD-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000036">
        <property type="entry name" value="Glutamine-dependent NAD(+) synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.110.10:FF:000003">
        <property type="entry name" value="Glutamine-dependent NAD(+) synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090:SF9">
        <property type="entry name" value="GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="11">
        <location>
            <begin position="4"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="699" mass="77548" checksum="7462A477DBF3EE79" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPM9</accession>
    <name>C1MPM9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56964</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057609.1">
        <property type="nucleotide sequence ID" value="XM_003057563.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MPM9"/>
    <dbReference type="GeneID" id="9683046"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56964"/>
    <dbReference type="eggNOG" id="ENOG502S5CA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2366" mass="258705" checksum="9A3A09BF003FF713" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ64</accession>
    <name>C1MQ64_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_16619</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat THOC6 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057703.1">
        <property type="nucleotide sequence ID" value="XM_003057657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ64"/>
    <dbReference type="STRING" id="564608.C1MQ64"/>
    <dbReference type="GeneID" id="9683511"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16619"/>
    <dbReference type="eggNOG" id="KOG0649">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FTEDWLL"/>
    <dbReference type="OrthoDB" id="273067at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000347">
        <property type="term" value="C:THO complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000346">
        <property type="term" value="C:transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042626">
        <property type="entry name" value="THOC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44411">
        <property type="entry name" value="THO COMPLEX SUBUNIT 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44411:SF1">
        <property type="entry name" value="THO COMPLEX SUBUNIT 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="211"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="392" mass="39933" checksum="2C46FCA92E34D1C0" modified="2009-05-26" version="1">MFDCRAPYNPGAYASLVKEERSASSRTVYATVFFAGAGASAGYLACGSSSGALSVWNLDDALGRARAADASGDDDAAVLPRVIVDAHDGAVYSVVSYEPDAGDADSRLLCTAGEDGVTNLYRVADLVSAACDASGSTGGVEGDRGRRADVRPVASFTNPQESRGRGALGPVPETTALAADATRGILFAAGGDGVTYGWDVTEGKKSPAFALKGHADALHCVASRGSCNQAVTGSEDGTARIFDVKSGKCTQVIDVWRAKGLGVGESGVGVGGGAWVGCVGLDKAENWAALGCGGRCVTMWSFAAGACASRSKTEMAPQTIKLTGEHVTAAGAEPAVYRWKLSGQLVSRQPCTPSSVFSLDMQNRGLTAVGGTGATVDLFSELGTRVCTLTCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ88</accession>
    <name>C1MQ88_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucose-6-phosphate 1-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_32934</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:16249"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58247"/>
            <dbReference type="EC" id="5.1.3.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glucose-6-phosphate 1-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.15" evidence="3"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057715.1">
        <property type="nucleotide sequence ID" value="XM_003057669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ88"/>
    <dbReference type="STRING" id="564608.C1MQ88"/>
    <dbReference type="GeneID" id="9683523"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32934"/>
    <dbReference type="eggNOG" id="KOG1594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MNWSITD"/>
    <dbReference type="OrthoDB" id="1659429at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047938">
        <property type="term" value="F:glucose-6-phosphate 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09020">
        <property type="entry name" value="D-hex-6-P-epi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025532">
        <property type="entry name" value="G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122">
        <property type="entry name" value="APOSPORY-ASSOCIATED PROTEIN C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122:SF39">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="357" mass="38758" checksum="E5E188E6B558C2B6" modified="2009-05-26" version="1">MSSAALASVGARPRVAPGRRVAVDARRATAARRGVSATVRASALNDRIVDDANAAFAIPGSVEFVAGEGGLPKCVLTHKNGGSAEVYLFGACVTSWCQPSGDDVLYVRPDAVFDKSKPISGGAPLCFPRFGPSDEMQQHGFARNSDWTVISSSADPNPDDPEPSVMFKLRDSEYTREMWDHAFEATYEVTLRRESLRMEFSVRNPLAEERKGRHEDAPFDFTAAIHTYIEVADATSPNVFARGLIGKNYIDKAIDPNVVHPEICAGDVVFGTSLCDKVFLKTEPETDLHVGTGAAVCVENTRGWTDTVVWNPHETLNIGDAWKKFVCVESAAVSEKIVLDSGKVWTAETNMFVADVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQF4</accession>
    <name>C1MQF4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_39326</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058118.1">
        <property type="nucleotide sequence ID" value="XM_003058072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQF4"/>
    <dbReference type="GeneID" id="9683186"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39326"/>
    <dbReference type="OMA" id="IRIEWSS"/>
    <dbReference type="OrthoDB" id="531519at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="12"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="202" mass="22891" checksum="3CF7A0FC35535F71" modified="2009-05-26" version="1">MTELKMSWVGRCGGCGKELRMKDDPPPAACARCKSRWYCGKDCQVKDWQRATNGHKEMCAVLAALTAKNDDKAMHRSMKTVDSTSEDLLSRCNEILEKQTKPGMQLREMIEDVVRKQKSSKKSRHLIMMGARTIEDNQCTLMALDEKQVKEMLKDDPDFARHANLVSSYDPSTELVIAFDVESPPNYIVFRAAMKDLPHGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQJ1</accession>
    <name>C1MQJ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_16082</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057769.1">
        <property type="nucleotide sequence ID" value="XM_003057723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQJ1"/>
    <dbReference type="STRING" id="564608.C1MQJ1"/>
    <dbReference type="GeneID" id="9683572"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16082"/>
    <dbReference type="eggNOG" id="KOG0133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DEWDISE"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF18">
        <property type="entry name" value="SI:CH1073-390K14.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="6">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="229"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="370"/>
            <end position="372"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="5">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="5">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="5">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="502" mass="54884" checksum="9CBC5908160BC4BB" modified="2009-05-26" version="1" fragment="single">MSAIGEASRVWLHHALRSLDVDVRATYGGGGVNFFAGAHGASLLAAANAIDAKIVFCTARHEPAHVARDAATAAFLEARGIALVTLPGHLLWDPRALKIDMRREKYFFGTLMPFVHAAETSGGKVAAPTPAPSAAPCVDLEGADLGADLGADLGADLGADASVRLTSLDDLGVSPRFPPGRDWSSGIRDEWDISERGANEVWASFTRRGLPEYEAEHGRADAVAPAASTSRMSPYLRFGQISPRAMYHDLKRADGKRVSRLFWHRVHRREFAYWQLANWPDMGTKSIRRHYDRRADWIPDPTRDAASAEILRRWREGRTGFPAVDAGMRRLWTTGWMHQTERMLCATFLCDYLNVHWVHGARWFHDTLVDADLAINAMMWQNAGKSGLDQWDVFSGSLAPDGSKPCRAHDPLGDAIATRVPELAGLPRGHLRHRPWEASDAVLETSGVVIRGAGEDGAYPERMLPGVGDVDGAGREDARARMISGVNDARRAELARAAAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQM1</accession>
    <name>C1MQM1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_4985</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="7"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058150.1">
        <property type="nucleotide sequence ID" value="XM_003058104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQM1"/>
    <dbReference type="STRING" id="564608.C1MQM1"/>
    <dbReference type="GeneID" id="9683588"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4985"/>
    <dbReference type="eggNOG" id="KOG2848">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NICWIAK"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="BRENDA" id="2.3.1.51">
        <property type="organism ID" value="13579"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004552">
        <property type="entry name" value="AGP_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00530">
        <property type="entry name" value="AGP_acyltrn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434:SF64">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="9">
        <location>
            <begin position="71"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="229" mass="25905" checksum="743816B12A3A26D7" modified="2009-05-26" version="1" fragment="single">RAMSFYLVSFTLALPLFAAMMVMFPFTYVSDKYRRYALSFVNDVWATISTLPFVKVRVVGREHLPAVDAPAVYVANHASYMDIYSLFHLRRPFKFISKVSNFIIPIIGWSMYMTGHIALKRTDRKSQMKTLKDCRELLQNDCPVLFFPEGTRSKDGVMADFKKGAFSVAAKERAPVVPVTIVGASQRMRSGREWAMSAGEIVLVVHPPIASDDAQELCDESYKVIKESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQM9</accession>
    <name>C1MQM9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57349</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058153.1">
        <property type="nucleotide sequence ID" value="XM_003058107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQM9"/>
    <dbReference type="GeneID" id="9683226"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57349"/>
    <dbReference type="OrthoDB" id="10692123at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="18"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="566"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="916"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="996"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1034"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1100"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1135"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="603"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1186" mass="125730" checksum="1BF052D407EEBB1E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR48</accession>
    <name>C1MR48_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_16040</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057869.1">
        <property type="nucleotide sequence ID" value="XM_003057823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR48"/>
    <dbReference type="STRING" id="564608.C1MR48"/>
    <dbReference type="GeneID" id="9683679"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16040"/>
    <dbReference type="eggNOG" id="KOG0552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LIPPICQ"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053111">
        <property type="entry name" value="Chloro_FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47598">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP17-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47598:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP17-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="2">
        <location>
            <begin position="88"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="191" mass="20016" checksum="0469B5985C6BF0FA" modified="2009-05-26" version="1">MGKGKRAGGQVNLFDPAASASRFITRRFGFGGALVFIGLLASVEGGEIVKAVLEDVTEKTGTGEEVVTESGLKYVDLKIGGGKSATKGDFVGIQLKLNDANDPSKVFVDTTAKGGRKIAFVYQRRPLLSPVFPGLEEAVSGMKRGGTRRFTAPPELGYGSEKVMLPDGTVVPGGTTLAVEVSLEEVSAMYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRU9</accession>
    <name>C1MRU9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1,4-alpha-glucan branching enzyme</fullName>
            <ecNumber evidence="4">2.4.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SBEIIB</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_44337</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Amyloplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="4"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058573.1">
        <property type="nucleotide sequence ID" value="XM_003058527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRU9"/>
    <dbReference type="STRING" id="564608.C1MRU9"/>
    <dbReference type="GeneID" id="9684375"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44337"/>
    <dbReference type="eggNOG" id="KOG0470">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WGRIDEN"/>
    <dbReference type="OrthoDB" id="196493at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009501">
        <property type="term" value="C:amyloplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11321">
        <property type="entry name" value="AmyAc_bac_euk_BE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651:SF4">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME 3, CHLOROPLASTIC_AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0035">Amyloplast</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="8">
        <location>
            <begin position="196"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="726" mass="82070" checksum="85FF29E410345CCA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRV2</accession>
    <name>C1MRV2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58242</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058575.1">
        <property type="nucleotide sequence ID" value="XM_003058529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRV2"/>
    <dbReference type="GeneID" id="9684376"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58242"/>
    <dbReference type="OrthoDB" id="10438850at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="304"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="520" mass="57249" checksum="A9729F6A049352A2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS36</accession>
    <name>C1MS36_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58334</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058979.1">
        <property type="nucleotide sequence ID" value="XM_003058933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS36"/>
    <dbReference type="GeneID" id="9684418"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58334"/>
    <dbReference type="eggNOG" id="KOG2551">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EEPRGWW"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="14"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="279" mass="29175" checksum="43E1630C16DE06CC" modified="2009-05-26" version="1">MGGPPPSSPPPPRKLKVLCLHGFTQNAETFRMRTGSIRKQLKSRIDFVFVDAPHDASGAFGESDASSLGAAATGESENDVGPRAWWLVGENAVEDALAAASSEARDEDEVADADENEAKPPTPPTRPAMSRQMRGWDATATRIADAVRTLGPFDGVLGFSQGASAAALALALVPSLRETVAFAILFSGFAPLDPTASAALFGPRDDGGGGGGGGGDTLRGVRSLHVWGTADGMVSRERFEELRSAFRTPEPETFEHDGGHGVPFSKEFRAALKAFALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSJ9</accession>
    <name>C1MSJ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57720</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058335.1">
        <property type="nucleotide sequence ID" value="XM_003058289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSJ9"/>
    <dbReference type="STRING" id="564608.C1MSJ9"/>
    <dbReference type="GeneID" id="9684133"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57720"/>
    <dbReference type="eggNOG" id="KOG1268">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="INEFPRI"/>
    <dbReference type="OrthoDB" id="7832001at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01908">
        <property type="entry name" value="YafJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052373">
        <property type="entry name" value="Gamma-glu_amide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187:SF1">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="398" mass="43600" checksum="2E91F4C5C89CA400" modified="2009-05-26" version="1">MCRWIFYYGEEVCIAKLIFGCTHGLATMSHGAGYTPGCELNHNRNHPVNVHGCGIGWYACEKCGLVDKHGLSAYDRPTVYTTVAAPSHDRNLRSLSKTISTSLLFGHVRAAGPGASVHQYNCHPFRKGRYMFMHNGEVVGFKSIRRGLLNKLRDELFEDISGTTDSELLFNLILNELPDVQTRQDTVTLQRAVLKGICAIISACKGKPSSLNVALTDGETVIATRYRNSEDEEPPSLYFHLGPMPGERAWDLNSLGGFDAMESNAKDTDIYGVRKSASQKSGFKKTGASSAGAERLMRNKFVATQALLVSSEPLSGDHGLDRWQLLPPNSMIVAAPTRPMAGRCTRSALVAKLKEEAMGGGKRHNLTPSSAPVLEIEIKVRSIHWSPYDPVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSS2</accession>
    <name>C1MSS2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57802</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058727.1">
        <property type="nucleotide sequence ID" value="XM_003058681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSS2"/>
    <dbReference type="GeneID" id="9683788"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57802"/>
    <dbReference type="OrthoDB" id="10624303at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="183" mass="18779" checksum="02BB25785CE48105" modified="2009-05-26" version="1">MGTDAATPPAATPSRPNPPNPTPPARRRPAGAPVVAPTVISSKAALLATAEDLADDVDAAEERLARRNGARTSRGGKEKDGIVGWTLEAVDRGLDSIERERPSTAQAAWKVASEAEKVAKNPTVQKGVKLTADAGIEVVKRAAPVIGKVAGNVGKFAAKSAFSAAVGGVFPKKKNDGGKSKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSS9</accession>
    <name>C1MSS9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57809</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058731.1">
        <property type="nucleotide sequence ID" value="XM_003058685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSS9"/>
    <dbReference type="GeneID" id="9683801"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57809"/>
    <dbReference type="OrthoDB" id="10643947at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="253" mass="26808" checksum="132EF40A044C1379" modified="2009-05-26" version="1">MGTTNGRPPLPAARRRHAARAQMSLKRRSMDLHAVANAAPSPLSEVDLARVHASRNLASATPELLSRDRATKRCRGADAEDAPSSSSSDDDDDAAARELARAHAARAGHVELATLLRSLRRGVLDAATETKLVHLNLAVGKHAGGRIFNLVLKSSHSWSRNDPSTVLAHLSRAERVGSNARLMGVLRHLLEATYPTAASVAAAEHVFDASGDEPLRGWCATHGVDATRVAVLEVMLYDASGAASNALCFPLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT28</accession>
    <name>C1MT28_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome P450 superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_57916</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058421.1">
        <property type="nucleotide sequence ID" value="XM_003058375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT28"/>
    <dbReference type="STRING" id="564608.C1MT28"/>
    <dbReference type="GeneID" id="9684226"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57916"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DGIHRIW"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010291">
        <property type="term" value="F:beta-carotene 3-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016123">
        <property type="term" value="P:xanthophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11046">
        <property type="entry name" value="CYP97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF171">
        <property type="entry name" value="PROTEIN LUTEIN DEFICIENT 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="651"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="2">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="702" mass="76859" checksum="3E7BF7C559944501" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT75</accession>
    <name>C1MT75_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_33459</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058437.1">
        <property type="nucleotide sequence ID" value="XM_003058391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT75"/>
    <dbReference type="STRING" id="564608.C1MT75"/>
    <dbReference type="GeneID" id="9684257"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33459"/>
    <dbReference type="eggNOG" id="KOG3506">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="521448at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.830.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="entry name" value="30s Ribosomal Protein S14, Chain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01364_A">
        <property type="entry name" value="Ribosomal_uS14_2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023676">
        <property type="entry name" value="Ribosomal_uS14_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="RIbosomal_uS14_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_uS14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004424">
        <property type="entry name" value="PRK05766.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010:SF2">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="94"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="160" mass="17852" checksum="C91221800FBEA82E" modified="2009-05-26" version="1">MGFANIWATKAECTGKGQRRCRVCANQWGIIRKYNLNICRQCFREYAKDIGFVKVRLASLHPSIVEMAWPLATSKASVCFRAGAPGPRPLAIASAAPRRAASSRAAWPRGGADRPRRRPSSSRCPRRRLSDFGEPRLVVRFVVADALVPPFPRFARTQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT80</accession>
    <name>C1MT80_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_8797</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058441.1">
        <property type="nucleotide sequence ID" value="XM_003058395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT80"/>
    <dbReference type="STRING" id="564608.C1MT80"/>
    <dbReference type="GeneID" id="9683879"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8797"/>
    <dbReference type="eggNOG" id="KOG0552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WDEGFAG"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF19">
        <property type="entry name" value="39 KDA FK506-BINDING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="21"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="106" mass="11269" checksum="3BDFF99A5083733A" modified="2009-05-26" version="1" fragment="single">NGMEIVNISMGKPNGAVAKSGKKVTMKYVGKLQSGKIFDQTRGNATFSFRLGVGEVIKGWDVGVEGMRVGDKRRLTIPPAMAYGKKGVKGAIPGNATLIFDVELVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTA9</accession>
    <name>C1MTA9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_58001</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058455.1">
        <property type="nucleotide sequence ID" value="XM_003058409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTA9"/>
    <dbReference type="GeneID" id="9684273"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58001"/>
    <dbReference type="eggNOG" id="KOG1919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ATPWINR"/>
    <dbReference type="OrthoDB" id="424794at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF87">
        <property type="entry name" value="RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="5">
        <location>
            <begin position="179"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="417" mass="44780" checksum="489BAF580B782AC8" modified="2009-05-26" version="1">MGEKLLYRTHLISVTGRHIVPAPGRGMSRVAPTPTPAPPRRTARVPSTSTRASARVEAMASSSASARFATVATGIVPPLPDDDADADAELDVAPDDGRWNLAKATLAAFPERYPTLTAARKAVRRGELRVDGVPRKGDYRVAAGAAVSVVARVSSGDALDVRDLPSDLPRLEIAYEDNHMAVIVKPEGMPSVGDGAWNAERALPYYLRETRRVEGALSRPRPVHRLDAATSGLLVCAKTRLAMTSLSVAFARREPKKRYRAVLAGAAGGWESGSEGVADAPLEGKPCVTRWRVDRVAPCSRHGRVTLMDFAPETGRTHQLRRHAAESLRCPIVGDFRYTKKSDDAFGGLDDRDGLFLAAVEISLPPSATPWINRGGEGAFAGEGEGGDDDDDDDGWLRVRIDDPEKFARRLGGVVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTE8</accession>
    <name>C1MTE8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="18">SNF2 super family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MICPUCDRAFT_58044</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058476.1">
        <property type="nucleotide sequence ID" value="XM_003058430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTE8"/>
    <dbReference type="STRING" id="564608.C1MTE8"/>
    <dbReference type="GeneID" id="9683915"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58044"/>
    <dbReference type="eggNOG" id="KOG0381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1002">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DHPYLIL"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001510">
        <property type="entry name" value="Znf_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00645">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01336">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50064">
        <property type="entry name" value="ZF_PARP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PARP-type" evidence="14">
        <location>
            <begin position="29"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="16">
        <location>
            <begin position="510"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="956"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="1054"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="12">
        <location>
            <begin position="510"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="410"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="551"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="419"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="463"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="491"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="614"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="632"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH56931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1251" mass="138362" checksum="F4AC4F5FD16E488F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTH6</accession>
    <name>C1MTH6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47311</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058492.1">
        <property type="nucleotide sequence ID" value="XM_003058446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTH6"/>
    <dbReference type="GeneID" id="9683931"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47311"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="622" mass="61064" checksum="8713052E4DC7F05B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTH7</accession>
    <name>C1MTH7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_2818</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058864.1">
        <property type="nucleotide sequence ID" value="XM_003058818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTH7"/>
    <dbReference type="STRING" id="564608.C1MTH7"/>
    <dbReference type="GeneID" id="9683932"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2818"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YTVFCEL"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF12">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="1">
        <location>
            <begin position="60"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="404" mass="45608" checksum="EDDE48E41D619FEF" modified="2009-05-26" version="1" fragment="single">IKQPAARDAAWNETHAWGAREMERVICDFGGFFRKVGQIMGTAKQMMPPAYLESFARTMDANPPTPFPVVKRVVERSLGCALSERFSRFDERPLATASIAQVHAATLRDDGRDVVVKVLVADKKMMIGDVASMLHTSIALKRVGLDNGVDFPTVFRAYQSVIEHEFDFNVEARKISEFREVFETHGLSDRVATPRVVDELSGARVLVMERVRGVKVLDALNRARRRGRVPRLPSRARDGVFHTVFRAWGVMLLRHGHYHSDPHPGNLMLRRDGKLAILDWGQTQIAPASYRAHLCRLVIHMCAEDPRAIANEVRTRSQVKLERPTTEALTALCYAYFDTRPSALAEINMFDLNNSPFLRNKIVQNTEEGFFTIRTVFLLRGMMRACGVTASMVSSWERDARAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTM7</accession>
    <name>C1MTM7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_58128</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. GCN5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058886.1">
        <property type="nucleotide sequence ID" value="XM_003058840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTM7"/>
    <dbReference type="STRING" id="564608.C1MTM7"/>
    <dbReference type="GeneID" id="9683960"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58128"/>
    <dbReference type="eggNOG" id="KOG1472">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HQPPKEW"/>
    <dbReference type="OrthoDB" id="1937912at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010484">
        <property type="term" value="F:histone H3 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05509">
        <property type="entry name" value="Bromo_gcn5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037800">
        <property type="entry name" value="GCN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750">
        <property type="entry name" value="GH11602P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750:SF3">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 12" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="113"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="14">
        <location>
            <begin position="365"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH57341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="470" mass="51907" checksum="37C0B3A1B00BA566" modified="2009-05-26" version="1">MEAIRSFFGGSSAGTGGGDSDGPPDAKRARRDEEEASIGGSDSDSDADGGGGGGDDDDDGGGGGGGGGANPGADGARGNANNPGGARDTLGQYAQREIHLRKQEDDGELVYKVIKNDGKEQHSEWLVHLKNIFSKQLPNMPKEYIVRLVFDPRHHSMICLKNDAVIGGITYRPFWRQNVGEIAFCAVSANEQVKGYGTRLMNHLKEYVCDKESMTHLITFADNNAVGYFQKQGFTKDVMMEREKWVGYIKEYDGGTIMECSLSAQVSYTEFPIMIRQQRKCVDEVVKTMSNAHVVYPGLKQFEQPPGPGGVYKPIPVDRIKGVKEAGWTPPGPPKYRLVHPGCGDGAPTPENLNRFMRALVNLVQNHIDVWPFLEPVNAEEVPDYYDVVKDPICMETIKDRVENGEYYVTLEMFAADFRVMFNNCRLYNAPDTMFYKCATRLEAFFESKVAAGITWKASRGSVSGYLNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTV8</accession>
    <name>C1MTV8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NF-kappa-B inhibitor-like protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Inhibitor of kappa B-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_58571</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059090.1">
        <property type="nucleotide sequence ID" value="XM_003059044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTV8"/>
    <dbReference type="STRING" id="564608.C1MTV8"/>
    <dbReference type="GeneID" id="9684522"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58571"/>
    <dbReference type="OrthoDB" id="498026at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043124">
        <property type="term" value="P:negative regulation of canonical NF-kappaB signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038753">
        <property type="entry name" value="NFKBIL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263">
        <property type="entry name" value="I-KAPPA-B-LIKE PROTEIN IKBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="9">
        <location>
            <begin position="64"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="9">
        <location>
            <begin position="97"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="120"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="269"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="277"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="408" mass="43975" checksum="8707FC7F5EAD718F" modified="2009-05-26" version="1">MGRGGSPSSSGRDDGELSGDAKTYQKLLRGARKGSLHRVKKYAKRLRRAPAVDLETRSAVQLDRARTALHLACDAGADDVIAWLLKRGADVAAVDADGNTPAHLLARHAAVRDRAVERLRKHGASAHARNARGETPTALAERAHEAHAASARAHAERRAERRRAESGGRGLGGGGGDDDGYEGFGDASARAAANEARRWREKLMDAAFAGGEIDEFGGGGGGVEAGESHRAFFESYGDEDDPDAYRWREEEEAYRRYVEEGISARKRKRVSETLDGNPRRSREDVARAHADATRARDAEAQRVLDDARRQDAEWREKTSRNAAAAAAASYRERWGRAAAMIDGGAVDLRLTDVPWPVSARVLTGDAVAAKRALRAALTRGAAGAAESRKARSIHWSPYDPVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU23</accession>
    <name>C1MU23_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58641</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059120.1">
        <property type="nucleotide sequence ID" value="XM_003059074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU23"/>
    <dbReference type="STRING" id="564608.C1MU23"/>
    <dbReference type="GeneID" id="9684575"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58641"/>
    <dbReference type="eggNOG" id="KOG0595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056281">
        <property type="entry name" value="MIT_ATG1a/b/c"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24497">
        <property type="entry name" value="MIT_ATG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATG1a/b/c MIT" evidence="3">
        <location>
            <begin position="68"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="322" mass="33069" checksum="7AF1962C7F6AB99B" modified="2009-05-26" version="1">MDASPPSEWHSAPSPPPPATPDERRERPQPGNANVPVLVGGIAAELAATAAALAAAAIATARGDAMATTTTSRAATLERAAAVLRDAAAERWESDHKLDALSLSLVSLNALHEALSLSRDASDAAEAAHVAATTIAAKEESEENAAETEARVVEVERLRAALDEKKKTVARLEASFAAAVSRAERAGVSVRAPGSGSDSMPDGADATYQASLRLGRAAAVEELTGNLACALDAFTRSTILLLFLLSEGTRFARTGERDSDDDQRASGGGGGAMLMFEGRERVARFTCAIAGRLSACADAADVANARARKVLGSAPDEAVAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUA8</accession>
    <name>C1MUA8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_58732</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059163.1">
        <property type="nucleotide sequence ID" value="XM_003059117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUA8"/>
    <dbReference type="STRING" id="564608.C1MUA8"/>
    <dbReference type="GeneID" id="9684904"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58732"/>
    <dbReference type="eggNOG" id="KOG0531">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NACSNRL"/>
    <dbReference type="OrthoDB" id="512658at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="521"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="699"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="549"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="569"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="614"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="650"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="730"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="806"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="825" mass="85532" checksum="4BCB26731ECDB3CC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUB8</accession>
    <name>C1MUB8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_7986</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059470.1">
        <property type="nucleotide sequence ID" value="XM_003059424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUB8"/>
    <dbReference type="STRING" id="564608.C1MUB8"/>
    <dbReference type="GeneID" id="9684910"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7986"/>
    <dbReference type="eggNOG" id="KOG0032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="444540at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051581">
        <property type="entry name" value="Ca-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34524">
        <property type="entry name" value="CALCYPHOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34524:SF6">
        <property type="entry name" value="CALCYPHOSINE LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="19732" checksum="910212BC4E54150D" modified="2009-05-26" version="1" fragment="single">ANGVHGIRNLGLNLRILDERNTGALPVKEVLYALEDAGSRMTPDEKNLVAKYFDLEQSGFVDVRALMRGIRGKMTAKRMDLVNQAWSTRIATNGEREVPVSVVQQKIDPTMNPDVFSGKKTFQQVVNEVPDHWDRNSDEMVSHGEFMEYYRDISAGLPDDEHFEMVIRNSWHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUF3</accession>
    <name>C1MUF3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_27251</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059486.1">
        <property type="nucleotide sequence ID" value="XM_003059440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUF3"/>
    <dbReference type="STRING" id="564608.C1MUF3"/>
    <dbReference type="GeneID" id="9684626"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27251"/>
    <dbReference type="eggNOG" id="KOG3203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KPWVVID"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="234" mass="25051" checksum="CE84075FD53C27F5" modified="2009-05-26" version="1">MAAHAMSANALVAKLGGVAVNKAATGAKKSACFTGGAAVPRASVRSAARVNATVRAAVSLPDGVTVEKMGKDVFNTSYYPKGEDTDNSRKPWVVIDAAGLRLGRLSTLVATYLRGGNVGTYSPSMNMGTYVVVVNASQVVVSGKKFEDKLYKRHETGRPGSMKEESFKMLQARIPERIVEKAVRGMLPKNRKGRELFTQLKVYGSEEHPHAAQNPIDVTAEVKELCYSSGMKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUN3</accession>
    <name>C1MUN3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58872</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059226.1">
        <property type="nucleotide sequence ID" value="XM_003059180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUN3"/>
    <dbReference type="GeneID" id="9684966"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58872"/>
    <dbReference type="OMA" id="STWKSAS"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040008">
        <property type="term" value="P:regulation of growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044194">
        <property type="entry name" value="BLISTER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47490">
        <property type="entry name" value="PROTEIN BLISTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47490:SF2">
        <property type="entry name" value="PROTEIN BLISTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="478"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="533"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="585" mass="63025" checksum="EEDFF6FC9BD4B50F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUN9</accession>
    <name>C1MUN9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cilia- and flagella-associated protein 251</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_58878</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059530.1">
        <property type="nucleotide sequence ID" value="XM_003059484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUN9"/>
    <dbReference type="STRING" id="564608.C1MUN9"/>
    <dbReference type="GeneID" id="9684668"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58878"/>
    <dbReference type="eggNOG" id="ENOG502QQ05">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YYAQIRA"/>
    <dbReference type="OrthoDB" id="4899631at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF13">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="172"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="705"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1070" mass="111819" checksum="897EEDFC3258041E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVF4</accession>
    <name>C1MVF4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_27535</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060029.1">
        <property type="nucleotide sequence ID" value="XM_003059983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVF4"/>
    <dbReference type="STRING" id="564608.C1MVF4"/>
    <dbReference type="GeneID" id="9685181"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27535"/>
    <dbReference type="eggNOG" id="ENOG502QQRM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IHWSHGS"/>
    <dbReference type="OrthoDB" id="10249837at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06460">
        <property type="entry name" value="M32_Taq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001333">
        <property type="entry name" value="Peptidase_M32_Taq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217:SF1">
        <property type="entry name" value="CARBOXYPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217">
        <property type="entry name" value="METAL-DEPENDENT CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02074">
        <property type="entry name" value="Peptidase_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006615">
        <property type="entry name" value="Zn_crbxpep_Taq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00998">
        <property type="entry name" value="CRBOXYPTASET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52034">
        <property type="entry name" value="PEPTIDASE_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="490" mass="54557" checksum="84E59CD2D975D82B" modified="2009-05-26" version="1">MSDLGAIEATLQWDELVMMPDAAAEARGRQKAALAELSHREATSAAHGDAIAAAERAHSGDGCAWRAAVIRDARRDYDDAIRLPGELKAREATLGARGYAAWVKARESDDWDSFAPTLEELVTLRKEMAAACADDGVEPYDYWLDQFERGMKRERLEEIFSVLRASLAPVIAKTLEAPKLEHHPALVSGTFPEDAQERFCRAIATKMGFDFNSGRLDRSVHPFTGGVGPIDVRITTRYDENNFMDAVMGTIHEVGHALYEQGLNAEQDGLPVQRALSMGIHESQSLFWERYVGQSLGFWRSVLPEFHASFPRTKEEGVTAEDLYRYVNKASAGFIRVDADELTYSMHVVLRFEIERAIFAGEASVAELPSLWRTKMRELLGVVPDTDALGVLQDVHWSDGSFGYFPSYTLGAMYACQFHARAREEIEGFDALVENGDLAPIREWLRRKIHAVGSLHPSADELCVAVTGAKLDPEVYVTYLREKYSALYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVQ8</accession>
    <name>C1MVQ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_34253</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059792.1">
        <property type="nucleotide sequence ID" value="XM_003059746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVQ8"/>
    <dbReference type="STRING" id="564608.C1MVQ8"/>
    <dbReference type="GeneID" id="9685231"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34253"/>
    <dbReference type="eggNOG" id="ENOG502QQQU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NIACCFS"/>
    <dbReference type="OrthoDB" id="439127at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF047558">
        <property type="entry name" value="TPR_END_plus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47661">
        <property type="entry name" value="PHOSPHOGLUCAN PHOSPHATASE LSF1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47661:SF3">
        <property type="entry name" value="PROTEIN CONTAINING PDZ DOMAIN, A K-BOX DOMAIN, AND A TPR REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="314" mass="34247" checksum="67E01A8F2363C164" modified="2009-05-26" version="1">MASVASLAASASAAVTGRALTSRRAAARASARTVVRAADVLPADGRTLDRSGVPNDPANEGLYDVTLPKPVGVKFARGNDGGAYVVSIPPEPMYDCFAIGDKVTKVSASFGDEIWDADSYGQIIYAMKNRNGDIYLQLRQMNGDLSALEQNEKSSGFKNERAGGNYGAGTKEQQMQNYSKKKELEVQRLDMFDEAIALYNKSDFDSALIIFEEVAALEPKNYMSDNFETATEIYRVSQYNIACCFSKLGQLDNSLKALRQCMGAGWKDFKKIRTDPSLSAVQAAPGFKELMDKFDEPLINENAIKFVKGLFGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXU7</accession>
    <name>C1MXU7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF819 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60295</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060757.1">
        <property type="nucleotide sequence ID" value="XM_003060711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXU7"/>
    <dbReference type="STRING" id="564608.C1MXU7"/>
    <dbReference type="GeneID" id="9685894"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60295"/>
    <dbReference type="eggNOG" id="ENOG502S0UK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PRICMAL"/>
    <dbReference type="OrthoDB" id="498753at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008537">
        <property type="entry name" value="DUF819"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34289:SF8">
        <property type="entry name" value="DUF819 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34289">
        <property type="entry name" value="PROTEIN, PUTATIVE (DUF819)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05684">
        <property type="entry name" value="DUF819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="459" mass="44568" checksum="F1B570C3863DBAFA" modified="2009-05-26" version="1">MACAAAPSAAARARAHARASRPRPSRASSARPATRRGRDLASAPSPSSSAPMLDRRRPRDARTRALALANADPTLAILASCALAASVAERRTTWGASVSSPLLAMGLGMSLATCGVLPPVSSQYDLVWTLLMPLAVALTLLGVNVRDAASKAGPVLRAFVVGAVGSVLGAVVAFAVVGAGMGEHAWRLASCLCASYVGGSLNYAATAQALGLSGSAAGQAALAAGMAADNLAMAGFLAVIGAVPAAAAAAGEDDGGGAGGDALDDATRSKATPATIAAALTCALLLIEGGKAIAAMIGYPGAALGVTGVLAPAFAAAAAAATSNATKIGGGGGGLFRGGDVIGGALMLVFFAALGAAADPRVAVAAGGPTLAFIAIQLCVHLATCFVVGWKILQLPTWAILTASNANVGGPATAAATAAARGWSSATQPAVIVGTIGYAIGTPLGLFVGQLLRVAYGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY78</accession>
    <name>C1MY78_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_19003</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060520.1">
        <property type="nucleotide sequence ID" value="XM_003060474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY78"/>
    <dbReference type="STRING" id="564608.C1MY78"/>
    <dbReference type="GeneID" id="9686261"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19003"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AKEWWER"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="155" mass="17287" checksum="31FE2DA1BEEB09F0" modified="2009-05-26" version="1">MLLDDTHTILVHSTKKRLYWLRKAADRGDAVAMNEIGYCYRFGYGVNRDYTKAKEWWERASGCGHADATCRLASCYRYGDGVEKNEAKAVEIYVKATELGSGGAAHALGRIYELRSCGVAENKTEALKWYRLAAERGVSDARVSVDRLELELAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYB3</accession>
    <name>C1MYB3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_59845</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060547.1">
        <property type="nucleotide sequence ID" value="XM_003060501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYB3"/>
    <dbReference type="GeneID" id="9685686"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59845"/>
    <dbReference type="eggNOG" id="ENOG502SCU4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="687050at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="148"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="10">
        <location>
            <begin position="373"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH55316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="521" mass="54613" checksum="D6709109ABF60C12" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYM5</accession>
    <name>C1MYM5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68936</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060301.1">
        <property type="nucleotide sequence ID" value="XM_003060255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYM5"/>
    <dbReference type="STRING" id="564608.C1MYM5"/>
    <dbReference type="GeneID" id="9686031"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68936"/>
    <dbReference type="eggNOG" id="ENOG502QRDE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HCIDNGV"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01299">
        <property type="entry name" value="Met_dep_hydrolase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057744">
        <property type="entry name" value="OTAase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="81"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="480" mass="51871" checksum="711FBE9983B15FDB" modified="2009-05-26" version="1">MVAGICFDNARILKEAGLPGSRAQYDEDGFPRAGYLSNGLSLYTFGDEIQGIHREREIQSNAMNVPPECTGFERVDCRGMTLMPGLIDSHVHVTASSANLRMPSTMPPSLLYARSVPILSGMLNRGFTTVRDCGGADHGLATAVEEGSIRGPRIVHCGKALSQTGGHGDFRGAGDVALASGACSCCNFTIGRVCDGVDACRAAVRDEVRKGAKHIKIMASGGVSSPTDRLENLQFSEEELKCIVEEARNAGIYACAHAYTDEAIERAIRCGVACIEHGNYASRNTVKEMRANGTYLVPTLVTYERLKIDGVANGMSQAMVDKVADLVEAGQKTLKAATEEGVMVCYGSDLLGDMHKYQAHSIKLHLDAGVSAARVLNSLTGTPGRLLGKPWSWMRAMKNINAKPHVSKEKSHLQQLRIGRLSPGFKADVILVDGDVANDPTVLMDENNIKLVVKDGVIVKNILDKKDDDDDRRKRVKRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYN6</accession>
    <name>C1MYN6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_59967</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060600.1">
        <property type="nucleotide sequence ID" value="XM_003060554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYN6"/>
    <dbReference type="GeneID" id="9686037"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59967"/>
    <dbReference type="eggNOG" id="KOG4748">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VANKQAY"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF4">
        <property type="entry name" value="ALPHA-1,2-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="402" mass="45146" checksum="3B27AE8903F5EB4D" modified="2009-05-26" version="1">MHARHVQHAGGIGHHEMSQRMPRHSSGGGVSVGGTMTELMTPMPPSPRNRSPPPELRGRERGGTLSGKGKQRRRLRKRYPTLAILATLMVLWTFSTAIYHVVMGFQKVYIRSMFFSIERPHYCPPSTPAPQDIADDDPIEGLPPADMKDLPSPIPSGKPKVGIVSLCDHNVDAICSASVANKQAYADHHGYDVIVDGDLIDESRPTSWSKLLVMRKYLPYYDFLFYVDVDTVITNVDVKLEDVVDYGYDQILAADKNGLNCGVWLIRNTPWSLWFLDEMWAQEQLVSPRTFVLFKFEQRAMHFLYQSRIWRTSVKGDAYKGANTIRARTKVVNSCVFNSLPAWYVKGDFLVHLAGLKGVAKCMMFRHYYATAQSEIVGKYGRLSAEADMPPPSLGTCLFGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYP2</accession>
    <name>C1MYP2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glutaredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_59973</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. CGFS subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060602.1">
        <property type="nucleotide sequence ID" value="XM_003060556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYP2"/>
    <dbReference type="STRING" id="564608.C1MYP2"/>
    <dbReference type="GeneID" id="9685748"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59973"/>
    <dbReference type="eggNOG" id="KOG0911">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAFSKRM"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000005">
        <property type="entry name" value="Glutaredoxin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF16">
        <property type="entry name" value="GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="8">
        <location>
            <begin position="89"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="176" mass="19504" checksum="EE6FBCF7357A2DAC" modified="2009-05-26" version="1">MTRARERDVIVAARAHHHERPHASRRVARRTGVPRLPDRGHDDRGGDVAVSRFRGFARDSDDDFKPQTHVTGDDAIQAAIATDVKENKVLLYMKGTPAAPRCGFSNMAVQILNFHGASFASRDVLSSEELRAGIKTFTSWPTVPQVFIDGEFIGGCDILRQMHDDGSLAKELEKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYT0</accession>
    <name>C1MYT0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_34792</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061092.1">
        <property type="nucleotide sequence ID" value="XM_003061046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYT0"/>
    <dbReference type="GeneID" id="9686277"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34792"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DWMLIFA"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="16"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="367" mass="39587" checksum="D5739B49505B3203" modified="2009-05-26" version="1">MAPPLTAWQLAGKAYFYVATWMSISMAVILFNKYILAFTRFKYPIALTLWHMCFCTSIATFMVRVAGTTKRLHMPRHEYVNRVVPIGALYAASLWLSNSAYLHLSVSFIQARSISHWFPYDRMTKALMPGLVYVCGVFLGMEKLTRSTSANMVVIAVGVAIAAYGEIDFVAVGVAQQLSALVFEALRLMLVQVLITRRGYAMNPIQSLYYVAPACAACLALPFATVELPEILNDIELVIDYPLLLLNGVTAFALNLAVFLLIGKTSALTMNIAGVIKDWMLIFASQHLFGNSCTFLNYFGYVVAFLAVGMYNVNKLKAAKAKERAERVGAKGGGGTAGGGGGGGGIAGAAAASSSSGGNSPRHDERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ99</accession>
    <name>C1MZ99_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_37555</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060921.1">
        <property type="nucleotide sequence ID" value="XM_003060875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ99"/>
    <dbReference type="STRING" id="564608.C1MZ99"/>
    <dbReference type="GeneID" id="9686617"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37555"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DQKSHIE"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF8">
        <property type="entry name" value="7ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="274" mass="28458" checksum="08EB0D53E3A9076D" modified="2009-05-26" version="1">MDSLRVPELFGVRGKNVLVTGGARGIGLMIASGFVANGADVYIASRDAAACDDVATKLTASGPGTCVALGSADLSTEEGCAALARAFREKIDAGALHVLVNNSGTSWGAPMRAHGEKGWDKTYDLNVKGVFFLTRELLPALDAGSREDDPARVINVGSTAGLRPQVFPTFSYDASKAAAHHLTKKLADELADRRAEGGASITVNAIAPGYVPSRMSQQLATYEEAKDVLKGGIPLRRRGNEKDMAGAALYLASAAGAWVTGVVLPVDGGFLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZE9</accession>
    <name>C1MZE9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_60707</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061203.1">
        <property type="nucleotide sequence ID" value="XM_003061157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZE9"/>
    <dbReference type="STRING" id="564608.C1MZE9"/>
    <dbReference type="GeneID" id="9686385"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60707"/>
    <dbReference type="eggNOG" id="KOG0143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FWTNDAW"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="186"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="383" mass="42024" checksum="007984B6127E9A49" modified="2009-05-26" version="1">MAGRGRPPPAAFAVPTIDVSAFEGADATASDDVVRRVKEACERVGFFVVINHGVSDARARDAMAAARGFFARPLEEKMKIASLKKGYIPVGGCDNAVRPTNMHEKYSCSRVDGVDAVSDPYYDASASPDAALYFGEQNRWPESPSGFREAWEEYYRAMETLASRLMRMFALALGADAHHFETRIDKHVTNLVALRYPPLDLDLDARADADADEGPDETIVERVKPHTDPTTLTILAFETGEAGGLQVLPDRRGDGGDASGSDTGAEVDEWIDVPSVAGGLLVNLGDVMRFWTNDAWKSTRHRVVARRETLALDRLSLIFFHMPNYDAVVDAGDFGAAVVNDARPRKYPAFKSGERSHFNQLMRDEEGLPDRQTLKEGTNARGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZR0</accession>
    <name>C1MZR0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_19576</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061264.1">
        <property type="nucleotide sequence ID" value="XM_003061218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZR0"/>
    <dbReference type="STRING" id="564608.C1MZR0"/>
    <dbReference type="GeneID" id="9686703"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19576"/>
    <dbReference type="eggNOG" id="KOG0338">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MIDPPKQ"/>
    <dbReference type="OrthoDB" id="10259843at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17947">
        <property type="entry name" value="DEADc_DDX27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF14">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="10">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="209"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="410"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="644"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="738"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="556"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="657"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="794"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH54914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="809" mass="89216" checksum="97D91516BD374DBA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZW6</accession>
    <name>C1MZW6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_45780</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061290.1">
        <property type="nucleotide sequence ID" value="XM_003061244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZW6"/>
    <dbReference type="STRING" id="564608.C1MZW6"/>
    <dbReference type="GeneID" id="9686465"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45780"/>
    <dbReference type="eggNOG" id="KOG2198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TQRKHFQ"/>
    <dbReference type="OrthoDB" id="6093671at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016428">
        <property type="term" value="F:tRNA (cytidine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000271">
        <property type="entry name" value="NOL1/NOP2/Sun family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057285">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057286">
        <property type="entry name" value="PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023270">
        <property type="entry name" value="RCMT_NCL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF1">
        <property type="entry name" value="RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25376">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25378">
        <property type="entry name" value="PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02011">
        <property type="entry name" value="RCMTNCL1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="11">
        <location>
            <begin position="78"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="205"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH54940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="714" mass="78237" checksum="721162451D378946" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N018</accession>
    <name>C1N018_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_48162</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HSF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061318.1">
        <property type="nucleotide sequence ID" value="XM_003061272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N018"/>
    <dbReference type="STRING" id="564608.C1N018"/>
    <dbReference type="GeneID" id="9686489"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48162"/>
    <dbReference type="eggNOG" id="KOG0627">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="22"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="283" mass="32332" checksum="2CE99A72118C2361" modified="2009-05-26" version="1">MAPTHLHARRPSCNPYAFDRVKVSPFIMKLHTLVSDPSASDVVSWNKDGKSFVVKDAKAFEKKLVGVLPVFPARVNINGFKRELNNYGFHKLGNDDDARLEFSHDGFVKGDPAALRQVTQKANVGRFRREKPQTAAKDMAPVSGFVLKNPFSLADNNNFGRFRRDADWEEKAFNPFDLENNNNYGRFRRGAKETDVAAAEDMAPVSGFDWKNPFSLADNNNFGRFRRDANWEEKAFNPFDLADNNNYGRFRRDANWEENAVNPFDLTDNRNYGRFRRAVQPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0P1</accession>
    <name>C1N0P1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51094</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061677.1">
        <property type="nucleotide sequence ID" value="XM_003061631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0P1"/>
    <dbReference type="GeneID" id="9687116"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51094"/>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317">
        <property type="entry name" value="BLR8090 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317:SF1">
        <property type="entry name" value="ZINC-RIBBON DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="28"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="115"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="182" mass="20817" checksum="61D1A1824DA767B8" modified="2009-05-26" version="1">MPKKKRGNNKGKPLVEWCDENGEHGTRLLLEYKDKQRKVGQVSYGSNYKALWRCVLCRTEWRTEVRSRTTGKNIHPTGCPECKVSGGAIKHATATDNFLTWCEENGQLGEKLRLEWCDDNDKKPTDVMRGSNYKAKWKCSIAECGHTWKATVASRTKSFKPTGCPKCHPPYANLRKRQRNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0Q2</accession>
    <name>C1N0Q2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_28590</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061679.1">
        <property type="nucleotide sequence ID" value="XM_003061633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0Q2"/>
    <dbReference type="STRING" id="564608.C1N0Q2"/>
    <dbReference type="GeneID" id="9686870"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_28590"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NHSARDD"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="356" mass="37468" checksum="B35DD0230A9F2EB9" modified="2009-05-26" version="1">MARDYYALLGVAKDADDAALKKAYRKMAMRWHPDKNKGSAEAEKKFKDISEAYDVLSDSNKRAVYDKYGEEGLKAGFQPGTPEGAPDGGGARYTFSNDDATRIFEQFFGGMGGMGGVGGMGGDDAGSASGMGGMGGGMPGMASMFGGMGGGGPGGGVRSTRGPPQCTVSRLPLSLEDLYSGCKKKLKITRRVNDATATNVPEGQAAMREVAEIVTVDVKPGYKAGTKLTYAGKGSEDPGRPGRASDLVIELDEKKHSTFERRGDDLVYRCAISLQQALCGFKLTLGGIDGAPVVVKVDDGRVISPGSAVKIQGRGMPSRKRPGERGDVVVEFAKIEFPNRVSPAQRNALKAAFKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1N174</accession>
    <name>C1N174_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_51288</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061762.1">
        <property type="nucleotide sequence ID" value="XM_003061716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N174"/>
    <dbReference type="STRING" id="564608.C1N174"/>
    <dbReference type="GeneID" id="9686959"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51288"/>
    <dbReference type="eggNOG" id="KOG3627">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="512168at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24253:SF153">
        <property type="entry name" value="SERINE PROTEASE HEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24253">
        <property type="entry name" value="TRANSMEMBRANE PROTEASE SERINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="228"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="82"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="552" mass="57258" checksum="FE6286BE2CEF4C39" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1R0</accession>
    <name>C1N1R0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51698</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061957.1">
        <property type="nucleotide sequence ID" value="XM_003061911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1R0"/>
    <dbReference type="GeneID" id="9687601"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51698"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="254"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="335"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="297"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="526" mass="55813" checksum="C6BDFA70A2038792" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1T4</accession>
    <name>C1N1T4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Dynein heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DHC2</name>
        <name evidence="18" type="ORF">MICPUCDRAFT_70272</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061968.1">
        <property type="nucleotide sequence ID" value="XM_003061922.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N1T4"/>
    <dbReference type="GeneID" id="9687614"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70272"/>
    <dbReference type="eggNOG" id="KOG3595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FHDSPYA"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000002">
        <property type="entry name" value="Dynein axonemal heavy chain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000003">
        <property type="entry name" value="Dynein heavy chain 12, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000223">
        <property type="entry name" value="Dynein heavy chain 3, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000009">
        <property type="entry name" value="Dynein heavy chain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000044">
        <property type="entry name" value="Dynein heavy chain 5, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001328">
        <property type="entry name" value="Dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000006">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000362">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF35">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="10 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0243">Dynein</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="17">
        <location>
            <begin position="617"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="17">
        <location>
            <begin position="898"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="17">
        <location>
            <begin position="1379"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1149"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1694"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="2274"/>
            <end position="2308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="552"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1150"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1698"/>
            <end position="1713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH53680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="3522" mass="386509" checksum="FDB78F0B163F53C6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N232</accession>
    <name>C1N232_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_51831</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Trp) + L-tryptophan + ATP = L-tryptophyl-tRNA(Trp) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="3"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062018.1">
        <property type="nucleotide sequence ID" value="XM_003061972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N232"/>
    <dbReference type="STRING" id="564608.C1N232"/>
    <dbReference type="GeneID" id="9687662"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51831"/>
    <dbReference type="eggNOG" id="KOG2145">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CIYDNFG"/>
    <dbReference type="OrthoDB" id="10261385at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000007">
        <property type="entry name" value="Tryptophan--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000033">
        <property type="entry name" value="tryptophan--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055">
        <property type="entry name" value="TRYPTOPHANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="436"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="487"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH53730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="538" mass="57792" checksum="69B5A96F090D820C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N267</accession>
    <name>C1N267_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51866</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062038.1">
        <property type="nucleotide sequence ID" value="XM_003061992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N267"/>
    <dbReference type="GeneID" id="9687677"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51866"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="455"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="562" mass="58335" checksum="3792017C49278B24" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N292</accession>
    <name>C1N292_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Twin arginine targeting family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_9774</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane. Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation. TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062049.1">
        <property type="nucleotide sequence ID" value="XM_003062003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N292"/>
    <dbReference type="GeneID" id="9687691"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9774"/>
    <dbReference type="eggNOG" id="ENOG502QSWH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NQHELKH"/>
    <dbReference type="OrthoDB" id="2017985at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.3310:FF:000003">
        <property type="entry name" value="Sec-independent protein translocase protein TATB, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.3310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33162">
        <property type="entry name" value="SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATA, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33162:SF3">
        <property type="entry name" value="SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATB, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01506">
        <property type="entry name" value="TATBPROTEIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH53761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="61" mass="6470" checksum="78401AC137B23068" modified="2009-05-26" version="1" fragment="single">SLFGVGAPEALVIGVVALLVFGPKGLAEIAKSLGQTLKAFQPTIRELQDVSREFKATLEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2M5</accession>
    <name>C1N2M5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_51589</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19949"/>
            <dbReference type="ChEBI" id="CHEBI:17836"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="EC" id="2.5.1.15"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11412"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the C-terminal section; belongs to the DHPS family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061901.1">
        <property type="nucleotide sequence ID" value="XM_003061855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2M5"/>
    <dbReference type="STRING" id="564608.C1N2M5"/>
    <dbReference type="GeneID" id="9687341"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51589"/>
    <dbReference type="eggNOG" id="KOG2544">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NIPHKLM"/>
    <dbReference type="OrthoDB" id="615426at2759"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="entry name" value="7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="FOLATE SYNTHESIS PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941:SF1">
        <property type="entry name" value="FOLIC ACID SYNTHESIS PROTEIN FOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="16">
        <location>
            <begin position="219"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="145"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="531"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH53613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="560" mass="58150" checksum="C58C95626AD10AE5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3C6</accession>
    <name>C1N3C6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_29176</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062356.1">
        <property type="nucleotide sequence ID" value="XM_003062310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3C6"/>
    <dbReference type="STRING" id="564608.C1N3C6"/>
    <dbReference type="GeneID" id="9688026"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29176"/>
    <dbReference type="eggNOG" id="KOG2187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QCNTIFV"/>
    <dbReference type="OrthoDB" id="10250660at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030697">
        <property type="term" value="F:tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.1070:FF:000001">
        <property type="entry name" value="tRNA/tmRNA (uracil-C(5))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01011">
        <property type="entry name" value="RNA_methyltr_TrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011869">
        <property type="entry name" value="TrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47790">
        <property type="entry name" value="TRNA/TMRNA (URACIL-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47790:SF2">
        <property type="entry name" value="TRNA_TMRNA (URACIL-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="20"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="469" mass="51844" checksum="B6429127E6A05A9C" modified="2009-05-26" version="1">MRATASGAAGLRATARRFLSGAAASSSHPPKRSAARPLAHGFRGAKKPKKPHDPTKVRAGLNVEVRPETYRAELDVKIADARACFDASPERDDGAGGGKPIEAAKIAVPLPDEIEVFESPKKHHFRMRAEFRVWHAGDKSFMAMFDNEDPKTPVEIETFPMGSERINSLMKEVLREIKDEPALRRKLFQVNFLTTSGTDDALVSMLYHRPLDAAWEAAAEEARQRMKVSVIGRSRKQKARLIVLGNPFVMETLTVDGEKFTYKQLEGGFTQPNSGTCEKMLEWARDVSVDDARAPGSGSGPAGARPRRRDDDFLELYCGNGNFTVALAPLYLNVLATEMSKVSVAAAVENFETNGTTNAKVVRLSAEELVLVLDSGKKYERMTNAGLDDLSAYDLRTLLVDPPRAGMGEEVSKFASRFDRIIYISCNPKTLAEDCRILAETHEIKRFAVFDQFPYTPHLESGALLVKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N452</accession>
    <name>C1N452_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_68810</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YIF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062732.1">
        <property type="nucleotide sequence ID" value="XM_003062686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N452"/>
    <dbReference type="STRING" id="564608.C1N452"/>
    <dbReference type="GeneID" id="9687926"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68810"/>
    <dbReference type="eggNOG" id="KOG3094">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="337750at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005578">
        <property type="entry name" value="Yif1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083">
        <property type="entry name" value="YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083:SF0">
        <property type="entry name" value="YIP1D-INTERACTING FACTOR 1, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03878">
        <property type="entry name" value="YIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="131" mass="14386" checksum="51D357589D6F1D15" modified="2009-05-26" version="1">MGMGMGGGGLPMSPKSIARFGMGAYGAQASAFVSNNYAKYFSSTAMRYYFDVNEAYVFNKLKLLACPFLHKGSWARIPEPFKPPRGDINAPDLYIPLMGFASYVLTNCILQVRSISHWSPYDPVCVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N455</accession>
    <name>C1N455_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_68812</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062488.1">
        <property type="nucleotide sequence ID" value="XM_003062442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N455"/>
    <dbReference type="GeneID" id="9687928"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68812"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="162" mass="16823" checksum="A222159B45CC3F7C" modified="2009-05-26" version="1">MESGMPPPLRPDTNRSFAFAVVEFTVTDATAGAPTTLQPVLRLNATGGGGAPTVNDHARLADAATREGAKHGALRSRVIGGGQLCFRGGEVSESAEYDDDREPRLVVTVRNGGGGESGGAQTKCADFEVVAALVRRAYPMHDMLTPGAFGAPGSADSKVYQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N473</accession>
    <name>C1N473_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68821</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062740.1">
        <property type="nucleotide sequence ID" value="XM_003062694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N473"/>
    <dbReference type="GeneID" id="9688180"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68821"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="131" mass="13900" checksum="8C449B63AA95F8FF" modified="2009-05-26" version="1">MIASNIAPANRAAVARCFPSFRIVFPDPAALTPSSASPYLAPSPLTTRYKSSSARTAATNPAPDASSSSRRSRSSRGPSLHRHASAADGARQSPSVSSLANLWVKRSVSRTSYRSNVEREVRVKSDDGESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4B1</accession>
    <name>C1N4B1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_36033</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the cytochrome b5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062757.1">
        <property type="nucleotide sequence ID" value="XM_003062711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4B1"/>
    <dbReference type="STRING" id="564608.C1N4B1"/>
    <dbReference type="GeneID" id="9688410"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36033"/>
    <dbReference type="eggNOG" id="KOG0537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VGHSPHA"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000002">
        <property type="entry name" value="Cytochrome b5 type B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF144">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="9">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="111" mass="11655" checksum="7B6B2B8BE1C3F694" modified="2009-05-26" version="1">MSEVEKHSSADDLWLVIDGKVYDVTPFMDDHPGGGEIMLSAAGKDGTQDFEDVGHSPHARELLKKFYLDEFAGGAASGKAATKSGGGGVSIIAVLLPLLVVLMAYFASKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4B7</accession>
    <name>C1N4B7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CYCB</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_36034</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin AB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062761.1">
        <property type="nucleotide sequence ID" value="XM_003062715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4B7"/>
    <dbReference type="STRING" id="564608.C1N4B7"/>
    <dbReference type="GeneID" id="9688201"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36034"/>
    <dbReference type="eggNOG" id="KOG0653">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YYEMCHY"/>
    <dbReference type="OrthoDB" id="5590282at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044772">
        <property type="term" value="P:mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20567">
        <property type="entry name" value="CYCLIN_AtCycB-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000013">
        <property type="entry name" value="Cyclin A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000167">
        <property type="entry name" value="Mitotic cyclin 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046965">
        <property type="entry name" value="Cyclin_A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0195">Cyclin</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="122"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="8">
        <location>
            <begin position="215"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="219"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="337" mass="38249" checksum="9B94C0414187E44F" modified="2009-05-26" version="1">MLNNFREKTQRGAAAPKWGRTSQRTTNTRPRDISNATGGTMTTRSGEPASKRESYTAYMEGRAAAEIPDIDALDRENPLAVTEYVNDIFSYWFRVEPDTQVAPNYMLIQTDINDKMRAILIDWLVEVHLKFKLMPETLFLTHNLIDRFLAKKVVTRKNLQLVGVTAMLLASKYEEIWAPEVRDFVYISDKAYTREQILGMEKQMLNTLGFHLTVPTPYQFMSRFFKAANADKQFQLLASFVVESSLPDYSMLKYPGSLLAASAVYVAMKTLGKGEWNDVMEAHTRYTEEDIRPCANAMARLQRKSATASLSAVHKKYSNPKFMEVARLPAPAGLGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4N4</accession>
    <name>C1N4N4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_52624</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063029.1">
        <property type="nucleotide sequence ID" value="XM_003062983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4N4"/>
    <dbReference type="STRING" id="564608.C1N4N4"/>
    <dbReference type="GeneID" id="9688469"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52624"/>
    <dbReference type="eggNOG" id="ENOG502SE0K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IITYLKW"/>
    <dbReference type="OrthoDB" id="543868at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053091">
        <property type="entry name" value="PSII_Assembly/Photoprotect-Rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37752">
        <property type="entry name" value="OS02G0610700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37752:SF1">
        <property type="entry name" value="OS02G0610700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="307" mass="31896" checksum="E414FF2B2F79A90B" modified="2009-05-26" version="1">MTTHTLSALSPTTTVSFAAKKTTTTRGVRGVSRRVASRGVVVVRARAVEEPPALNAVERSARSMGLDTSEGVFGFTPFAELWTGRLAMMGFTVGLAEELWTGDGILAQIGIACPNPIATSILTLGLVGGTVAGAAKTLKSAQDGTMTMRTFKRWCDLLGADQDEAARALSVDIKKMERNGFLAPDDLAAIAEARRSNPADAVLSMDGKAEAMAAAAAMKIAAAEAGEAAEASMMERDLAVGMPPMEIGAGVDAEMRYALDVEMNNGRWAMLGFALAVFLEASTGNGIMGQLIGYAKALGVLGPDSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N511</accession>
    <name>C1N511_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_21992</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062888.1">
        <property type="nucleotide sequence ID" value="XM_003062842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N511"/>
    <dbReference type="STRING" id="564608.C1N511"/>
    <dbReference type="GeneID" id="9688328"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21992"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="188" mass="21141" checksum="98DDD16D6876CE5E" modified="2009-05-26" version="1">MSWKTKCEYILGIEGVLDLPETRFHALLEQAGADLSNTNEQCNLGFFYDSSKRYDKALEWYMKGARQGSEVCENNIGISYRFGQGVEKNIDTALEWFTKSAEKDHAGAQYEAGAIHYDEGRYEEAFQWFTKSAAQGDTDATLDLGECYEKGNGVKKDISEALKLYGKAIEKGHAEAKENLRRLVDALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N561</accession>
    <name>C1N561_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52811</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063111.1">
        <property type="nucleotide sequence ID" value="XM_003063065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N561"/>
    <dbReference type="GeneID" id="9688356"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52811"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="108" mass="12312" checksum="8895CF443E6F2AF9" modified="2009-05-26" version="1">MSTAFQRKIGAAHARFGNPRKQPARHPTRTEEEERKTRACVEPDGASRSSVLTRQDEKKILHHRDRKKYSYKRPRVPQIMHESVSSSTGVWNHRDCQSSAGATLSIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5K5</accession>
    <name>C1N5K5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_63694</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063174.1">
        <property type="nucleotide sequence ID" value="XM_003063128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5K5"/>
    <dbReference type="STRING" id="564608.C1N5K5"/>
    <dbReference type="GeneID" id="9688614"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63694"/>
    <dbReference type="eggNOG" id="KOG2375">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MAIAMDE"/>
    <dbReference type="OrthoDB" id="2275718at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045117">
        <property type="entry name" value="ATXN2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009604">
        <property type="entry name" value="LsmAD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025852">
        <property type="entry name" value="SM_dom_ATX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854">
        <property type="entry name" value="ATAXIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854:SF7">
        <property type="entry name" value="ATAXIN-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06741">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14438">
        <property type="entry name" value="SM-ATX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01272">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LsmAD" evidence="2">
        <location>
            <begin position="189"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="480" mass="47721" checksum="7556149C556A4B74" modified="2009-05-26" version="1">MAASTLTPARERLAFVSQVLVGYQVEVALTNGAVYEGVFHAGSPSDDKWEKNDFKIVLKMAELKMHPKGADGSAPKRATRSIPSPSTTFVVADVVSVKAADVGMSDLAVGPSRAMGDGFTDGGISKGERLERELVAWTPGEDDPSDPSGGLLEDPAKRASNHRGGGGGGGGGANGGGAWDQFAANKNMFGVDTTFDESMYTTSIDRSKAGISEREAARIAHEIQTSASSNVHVQEERGQRTTTDYDEEDRYGAVIGTGAAHGGAHDAKTTRDGAPMPSRNAWAAGAVPASVKPPPPAAAAAAGAIPKPAATVAAAGVSSSTLAAPAEAAKMSTLSANAKPFTLKASAPAFVPAAKKPVATAAPTAFGAPVAPGGYPGYPMGGVGMNPAAMYAMGANMGMYGGVGRGPGMIDPRAAAAAAAAAAAQAAATAGFMRQMPPFGMPPGGRPPAPMAPMGGPAAVAAAAGAMPPADAPASNGDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5L0</accession>
    <name>C1N5L0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ETFB lysine methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein N-lysine methyltransferase METTL20</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_48785</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyltransferase superfamily. ETFBKMT family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063381.1">
        <property type="nucleotide sequence ID" value="XM_003063335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5L0"/>
    <dbReference type="STRING" id="564608.C1N5L0"/>
    <dbReference type="GeneID" id="9688617"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48785"/>
    <dbReference type="eggNOG" id="ENOG502QQTZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PEWQTPP"/>
    <dbReference type="OrthoDB" id="419617at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050078">
        <property type="entry name" value="Ribosomal_L11_MeTrfase_PrmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43648">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43648:SF1">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH52517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="419" mass="43718" checksum="DE42BA96391602D3" modified="2009-05-26" version="1">MAAATRLALLPRVLRRVAPRCAIASSRTSSSATTTTAAATAAARARASSPPPPRAIVWKRNNNDRVVRRASSSSSSSSSSSSSNPPPVELGGVDCVRIASLAGVDVGELEDALLSAGATCVVVEDADRGTTEEREIFGVGQGVWRRCDVTAMFKPGADVDDVMSRTTEILGLAPDALRYVAEHVPGEDWVNVVKDSFAPTKVLDGAWIVPEWSRDASLSRWGASDAESETALRVVLEPGLAFGTGEHPTTRLCLGWLWRRREVLRGAKVVDFGTGSGVLAIGARLMGATRAVGIDLDPMSIRAAAINAELNGIAVGGANDDDDGDDSFVLAVADGSRDEDLPDGLRGDVDVLVANILVGPVVALAPLFASYVKPGGSVCLSGVLETQTPAVIEAYEAAGFEALTRESEDGWAVVSGVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6B1</accession>
    <name>C1N6B1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_42814</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063502.1">
        <property type="nucleotide sequence ID" value="XM_003063456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6B1"/>
    <dbReference type="STRING" id="564608.C1N6B1"/>
    <dbReference type="GeneID" id="9688747"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42814"/>
    <dbReference type="eggNOG" id="ENOG502STI0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FAWTGFV"/>
    <dbReference type="OrthoDB" id="10267969at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF17">
        <property type="entry name" value="PROTEIN MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="16"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="276" mass="29991" checksum="23D2D48E1D8C62C2" modified="2009-05-26" version="1">MAGRFPSRAFARGFSAGGGVRRRLGGGGGGAGPRRDVSRADAASNRAISSGASNGGKSGASSSSSSSLNGLLQRYAAMNEAHPTTTRVGTGVVILCVGDVAAQRIQHEGSRDRDSKPFAIDARRLAAFASFGAIYTSWFQMHWFRALQRWFPRRSVMALSTATKRPSLIRADVLAPLLINQFVAVPTLYYPFYFAWTGFVRGFTAEESIALARERFTPRLLCQNWAFWLPAQFAQFAVVPPGYHILYVSGMGLAWNTILSLRCVLYTGPHTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6C6</accession>
    <name>C1N6C6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42823</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063315.1">
        <property type="nucleotide sequence ID" value="XM_003063269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6C6"/>
    <dbReference type="GeneID" id="9688948"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42823"/>
    <dbReference type="OMA" id="MVVMTSP"/>
    <dbReference type="OrthoDB" id="10669403at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="402" mass="43487" checksum="65570F273CDCE128" modified="2009-05-26" version="1">MTSCGTAIPPRAARPRAALDGGRARASATGPWRAVATTRPRREPTLSSSTTSSLSLSTSSSTTTTRRRRRGSIATRAAGGGDGRFRDDRERRAAIDRLSPPSSSSADDDADGGDTPSPSRSPAKSKTRPKRFKDAMRQRDDFIESRLRARAEDAANEGEKTGETDPRVAARKRRLERRDAARSDRDAYVVSVIRRELGTPRDIVGGVDGDTRARRFASLAAALKNFSTFEVMTGLVRYYYAHWDEGEASRGGGGGGGGGGGDDDDDDEDESRSAEREGLEVAKSYSEAENEEERRRLLRDAQLRATGIEPGSSFDKSRLSGSFDDDGGDGDGDGDPLTRLAAFIREYFAVDFVETDDGGKEMVVMTSPEFLVFLLVAVILSGRLGHFIVQTYLSGATDPLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6Q1</accession>
    <name>C1N6Q1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_22895</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063590.1">
        <property type="nucleotide sequence ID" value="XM_003063544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6Q1"/>
    <dbReference type="STRING" id="564608.C1N6Q1"/>
    <dbReference type="GeneID" id="9689214"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22895"/>
    <dbReference type="eggNOG" id="KOG0029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IRNHLLC"/>
    <dbReference type="OrthoDB" id="2219495at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF373">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIRM" evidence="3">
        <location>
            <begin position="27"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="596" mass="64519" checksum="8EF64278553255D4" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N710</accession>
    <name>C1N710_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53512</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063825.1">
        <property type="nucleotide sequence ID" value="XM_003063779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N710"/>
    <dbReference type="GeneID" id="9689088"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53512"/>
    <dbReference type="eggNOG" id="ENOG502S381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DWHVYLM"/>
    <dbReference type="OrthoDB" id="567985at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053021">
        <property type="entry name" value="Chloroplast_ADK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35509">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (DUF1995)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35509:SF5">
        <property type="entry name" value="SAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="372"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="416" mass="44375" checksum="26020C580E08EEDD" modified="2009-05-26" version="1">MATPMKTLHRVATTATTRRAPRAPTTTPARRPRPRRRLSSRSGSDRDASSAARAAPNDASSSSTTLAPLPQTCAEQVAACASCVVAAAASGARRQRLTLLLPTNNRGDDFTSTERADYEANADAVYRAAMETAAAVMRRVDANGGDITATRVDDDNDPVGVLRNAAGSVRAVVIPNAQQLDVLRKLAEESERGRDAGDAAITLLVNPQWNESGQIISDFGVGPWKRRAFDFLDTFAPAFHLTETRVGAASTRDPAKGGDYMGTGGVARILKTHGGAWQVFAMGGDGSSECVRVEESEPTYEYLNAEVFVTPEYSLARRRRGAGPSMERRLEASARSVSASADDDDVAVDWSIASSAEIAAAVRVKAIRARDVDAFDKTGLRSALTALGLPTSGKVEGLRERLREALLGEDAEEWIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N739</accession>
    <name>C1N739_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_43013</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063835.1">
        <property type="nucleotide sequence ID" value="XM_003063789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N739"/>
    <dbReference type="STRING" id="564608.C1N739"/>
    <dbReference type="GeneID" id="9689276"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43013"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="747"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="555"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="756"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="792"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="878" mass="90121" checksum="EBB1C75F1022F20E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N755</accession>
    <name>C1N755_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_53561</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063675.1">
        <property type="nucleotide sequence ID" value="XM_003063629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N755"/>
    <dbReference type="GeneID" id="9689116"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53561"/>
    <dbReference type="OrthoDB" id="514895at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="222"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="302" mass="34586" checksum="68DA5DC3B8C2E81C" modified="2009-05-26" version="1">MRQWWETLGRSDVVTTERVEEGAINACRVAAENGVVRAMMDLSIAYDSFASIRNEKKAFQWAERAYGNGACFRGCFERDPSTGKPWEPGKRDEYLKLDSVHGVVYGVNYLLWYLGIKYACGLGCEINYMRGLFLMLRAIELGYDNDGDAEGLMKFVALIRFRASGLDVNTPTKEELVAWMENHPDVVSSFDMHHPPEELRKVFEQVQVAALANKELKHMRRCRNCCAESENLRICARCKSVCYCSKECQEMDWRLGLWPHKSICDKMARLWDERPGRSDQEALASLSKSLATQYVEMWGAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Y5</accession>
    <name>C1N7Y5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53877</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064174.1">
        <property type="nucleotide sequence ID" value="XM_003064128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Y5"/>
    <dbReference type="GeneID" id="9689615"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53877"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02116">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04873">
        <property type="entry name" value="ACT_UUR-ACR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="314" mass="33286" checksum="5C6DC1F83F677ACC" modified="2009-05-26" version="1">MDARAAVSPSSLTPSFPPPRVAVVYTPRPGLFADLCLCVDAQGLRILRAEISGAGALRAYRFWVVDDETAFKLEHAHLNPISLAIRDAVVKQGAWHSVHGADAVKISGEAFLRVDAPRHALSLRRDFLFPSSLLSHPSRSIPTHLDTFQLQLIDAPLNSTPTFALNDGPSTLRAPDRVGLLRDVAATLLHRGVDFDSLRTFTAWGSDSVPTAVVEGSVVADERVAERVGTRVSGGAEWEEVMRALRDVAVGGLERGGVPASAIATMTGGRGSPTRTAHADDAMEGAHDDERGGGGGTISRAKAGAGMRKARSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8Q4</accession>
    <name>C1N8Q4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_23576</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064487.1">
        <property type="nucleotide sequence ID" value="XM_003064441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8Q4"/>
    <dbReference type="STRING" id="564608.C1N8Q4"/>
    <dbReference type="GeneID" id="9689928"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23576"/>
    <dbReference type="eggNOG" id="KOG4412">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RTTCLHW"/>
    <dbReference type="OrthoDB" id="541596at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="82" mass="8705" checksum="37D0EC76404F0514" modified="2009-05-26" version="1" fragment="single">MATSIVSLVDILHAAVSRGDADRVRSLLENGAPVNARLRHRTTCLHWAASEDAHEIVETLCRAGADVNATAVDGCTPLHYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8W5</accession>
    <name>C1N8W5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54266</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064345.1">
        <property type="nucleotide sequence ID" value="XM_003064299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8W5"/>
    <dbReference type="GeneID" id="9689786"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54266"/>
    <dbReference type="OMA" id="MAMAMEY"/>
    <dbReference type="OrthoDB" id="10579887at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="318" mass="35099" checksum="CCE1EB2A46A0C973" modified="2009-05-26" version="1">MAMAMEYEEYAATSSSKHHGWKLEVSRAHKERRDMDDLEVMNAARASRPRKRKRIRPSVDREIRRRRLSAATSPPRSHSLPPLPQERLARVYAKIDVGDTVADLTSPGAVARLRRVRCKHSHTEMDRLGIGPRASTRYLTYPERAERHYDDDDDDDDDDYHDDRVAPPPRDDDGERALVGVAAARKRTEDVIAATPLVTPSDAVGRVGRVSDSVCRTKTSAARAPPPPPLPSTAARGAVAVAIAAAPTGGLTSRRSRTGDEEGAMTTTSTRPPRRILYDASVGVEPRRGRTDAEKEAHMLDADGEMPKSAYRDLEALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8Z2</accession>
    <name>C1N8Z2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_37032</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064365.1">
        <property type="nucleotide sequence ID" value="XM_003064319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8Z2"/>
    <dbReference type="STRING" id="564608.C1N8Z2"/>
    <dbReference type="GeneID" id="9689967"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37032"/>
    <dbReference type="eggNOG" id="KOG2171">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PKRFVQE"/>
    <dbReference type="OrthoDB" id="543373at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041653">
        <property type="entry name" value="Importin_rep_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041389">
        <property type="entry name" value="Importin_rep_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18808">
        <property type="entry name" value="Importin_rep_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18829">
        <property type="entry name" value="Importin_rep_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TOG" evidence="9">
        <location>
            <begin position="342"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="8">
        <location>
            <begin position="402"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH51270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1117" mass="121173" checksum="FA68852CCE5FEA74" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N930</accession>
    <name>C1N930_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66563</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064383.1">
        <property type="nucleotide sequence ID" value="XM_003064337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N930"/>
    <dbReference type="GeneID" id="9689987"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66563"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="84" mass="9800" checksum="5934485D8512717F" modified="2009-05-26" version="1">MACASWRLTGPAAAAERTNERTVPRERERSTRGEYRARRRHDRGRERRRERTRRRGTQWTGGGPGVDDAHQKFIIHSSSRVSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Z8</accession>
    <name>C1N9Z8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cystathionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Gamma-cystathionase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_70947</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064701.1">
        <property type="nucleotide sequence ID" value="XM_003064655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Z8"/>
    <dbReference type="STRING" id="564608.C1N9Z8"/>
    <dbReference type="GeneID" id="9690264"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70947"/>
    <dbReference type="eggNOG" id="KOG0053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RPDNPTY"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004123">
        <property type="term" value="F:cystathionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000046">
        <property type="entry name" value="Cystathionine gamma-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF15">
        <property type="entry name" value="CYSTATHIONINE GAMMA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH51035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="436" mass="47535" checksum="62ECE4E1CF4FB5FF" modified="2009-05-26" version="1">MSPPSSPPSSAYSPPISYSPPPRLSPWRGVSVDTILAQAGGDALGLPHAASTLLGDATGSLVPPIFPSTTYARDAETYAPRVLPSQLVYSRPDNPTYARCERVLAALDRGVDAMLFASGMAAVSAVAHATCARGDRLVCPRRCYFAVRAFFQAHCERFGIEFALYDQARSMHWSPYDRVRVVDATAEGDLERVIGEDKKTKLVWVETPANPTWELTDIRRAAEATRKFGAKDAALVCDATALTPVVCRPIEYGADFTLHSATKYLNGHSDVVAGAVVAARESKVWDEMKRQRTMSGAVCSPFDAWLLLRGLRTLHVRVERQCATALRCVLYTANYLYGGMLSIRVKGGKDAALRVVSRLRLWCPATSLGGVESLVEHRYTVEGPDSGVPDDLLRLSCGLEDAADLYEDLRRALDAEADREWVKEKGGGGGKRAKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAB7</accession>
    <name>C1NAB7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54834</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064937.1">
        <property type="nucleotide sequence ID" value="XM_003064891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAB7"/>
    <dbReference type="GeneID" id="9690378"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54834"/>
    <dbReference type="OrthoDB" id="10647558at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH50917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="440" mass="49354" checksum="4F8E3B025D462FA2" modified="2009-05-26" version="1">MPRVRSSYKKSSRTCRVFLLSCCLLTFVVLSTKRSLSELRRNHLAAVEALSRDARWKTLHDPKGGGGGGAYYPPSKLCRSGTNDTRTLGAATPGNFGFVFGGLGGYARLEAFKCVLAIESLVRVAGYDGDVYFITENIASSCVPSQEELRARLGYDRVHVVYVDEGSPFEKSSDAERTNGTRSRRRPLRKYLKDMSIKMDIFDYLPKRIEIAAWYDCDVVFGVHGCARNNLMCAIPEFSHATPMYTSLGSAGWHVGSFMVHRVFSAKLLREWKEEFFTGRHISDYPAIEALYERQERTGNLLKLWDIGHFTRPRTGNTYSHDWSVLTSDPSAGEMYSAWRDVIFDKKTPNSCIMHLTTGRCSELNSGTVATDALIRSLGLFTPGNVRYCSGTPRKVILQQGLAPSWKSCVPPPADFVFPLKARLLQRMISPRHINKTRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAM6</accession>
    <name>C1NAM6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calmodulin-binding motif family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55846</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663754">
        <property type="protein sequence ID" value="EEH50849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064991.1">
        <property type="nucleotide sequence ID" value="XM_003064945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAM6"/>
    <dbReference type="STRING" id="564608.C1NAM6"/>
    <dbReference type="GeneID" id="9690433"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55846"/>
    <dbReference type="eggNOG" id="ENOG502QSTG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10253073at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33504">
        <property type="entry name" value="NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33504:SF2">
        <property type="entry name" value="PROTEIN MFI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="449" mass="49768" checksum="11B256DF53A48F4C" modified="2009-05-26" version="1">MDDAVGDVVDDDADRTVVDAVVDAVVDDAVTRASSRPSTSTSSTPEPARKNFDASFREFVVTKLQARARGKSKRDAYARVQRAVRCIQARWRESERRAAVRRPRRRRRSSSSSRIVCRADYDRVSSPRGPSSAARSPPPAPVDRSRVPTAQARPDYHAMASRIARAWRRHLRIRVFRRLRDLVASNNEKSDPASALRRVNPAEAAVAGDPSCGTHVRFRLGGETFPPEVVYKIYTHRPVTDVCAFAPRDYAASRAAAAGSRDRSSERPSRRGWYARVENNAWRPVRDVGALEERENETTASARRESIRDAYTFHLSPSARRDATERRRRERRVEWMRKLYGFQAMRRGGGGGSDAGAGAPRGSGSTRVDADGDDLDLDVDATFAQTDEERALLSWSSALDFDAYQRMWSTLSCGAPSESTAPRGIGETAIEASARLGLSDANAFGGYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH51</accession>
    <name>C1MH51_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_24102</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054891.1">
        <property type="nucleotide sequence ID" value="XM_003054845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH51"/>
    <dbReference type="STRING" id="564608.C1MH51"/>
    <dbReference type="GeneID" id="9680760"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_24102"/>
    <dbReference type="eggNOG" id="KOG0857">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HHVIREN"/>
    <dbReference type="OrthoDB" id="10258869at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010224">
        <property type="term" value="P:response to UV-B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001197">
        <property type="entry name" value="Ribosomal_uL16_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003239">
        <property type="entry name" value="PRK04199.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00279">
        <property type="entry name" value="uL16_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11726">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="227" mass="25884" checksum="C5B0D6A80A828564" modified="2009-05-26" version="1">MARRPAKCYRVIKNKPYPKSRYCRGVPDPKIRIYDAGMKKYPVDAFPTCVHLVSFEKEQISSEAMEAGRIAANKYMVKNAGKDAFHLRVRMHPFHCLRINKMLSCAGADRLQTGMRGAFGKVQGTAARIAIGQIMLSIRTKDVHANKAVEGFRRAKFKFPGRQKIVVSRQWGFTKFKREDYVAWKKEGRILPDGVNAKLWENHGPMEGRPAESLFLAPARVYKERAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH56</accession>
    <name>C1MH56_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_46181</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054893.1">
        <property type="nucleotide sequence ID" value="XM_003054847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH56"/>
    <dbReference type="STRING" id="564608.C1MH56"/>
    <dbReference type="GeneID" id="9680556"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46181"/>
    <dbReference type="eggNOG" id="ENOG502S994">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PEIYVIH"/>
    <dbReference type="OrthoDB" id="1368at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="427" mass="48066" checksum="204C5EF7269C3B42" modified="2009-05-26" version="1">MSRATTTGVVLDVRGDDVDARRESSPRATSYAPDGSATREDASSAELSRPRSNRAPSTTRAGRLWDTMLDPDATRRRDAHFARANEVGHHRAYDYSSWTDTTFAVGLRARAVNNFRWPWALVNGVTIVWCALARNVDALDWDLTAFERGYALIFSLLAFLLVFRVNRAAVRWWDCRTAWGAIVLGGRLLADDAIASVRDVYPAHVDDLARWFVAFAVATKCHLRRETRIDPASLAGVVDDGELDAMRTRATHAPLYCASRMREAVTRMTREPDPNAPRPSEEWRDRVRWERARMHWSLAAALNARMTSRIDALVGHCGAQERIRATRLPIVYVTHLRTFLMGYLLSLPFVFVRDWGWGTVPAVACVSFALLGVEGAAHECENPFSANHANHLGMDVYCETVNKEMCEYLRLWREEKLDSKEGGGDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHI6</accession>
    <name>C1MHI6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_49392</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055500.1">
        <property type="nucleotide sequence ID" value="XM_003055454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHI6"/>
    <dbReference type="GeneID" id="9680306"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49392"/>
    <dbReference type="eggNOG" id="KOG2492">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YLQPAEM"/>
    <dbReference type="OrthoDB" id="190098at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035599">
        <property type="term" value="F:aspartic acid methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12160:FF:000003">
        <property type="entry name" value="CDK5 regulatory subunit-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.30.20:FF:000001">
        <property type="entry name" value="tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="entry name" value="Methylthiotransferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="entry name" value="tm_1862 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_uS12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01125">
        <property type="entry name" value="30S ribosomal protein S12 methylthiotransferase RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00089">
        <property type="entry name" value="MiaB/RimO family radical SAM methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="RIBOSOMAL PROTEIN S12 METHYLTHIOTRANSFERASE RIMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN US12 METHYLTHIOTRANSFERASE RIMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01082">
        <property type="entry name" value="B12-binding_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="9">
        <location>
            <begin position="63"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="217"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="20"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH60752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="525" mass="57603" checksum="469DF1F3D54E7071" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHQ8</accession>
    <name>C1MHQ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_49396</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055537.1">
        <property type="nucleotide sequence ID" value="XM_003055491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHQ8"/>
    <dbReference type="STRING" id="564608.C1MHQ8"/>
    <dbReference type="GeneID" id="9680602"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49396"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WRHSIWA"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="PiNMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF11">
        <property type="entry name" value="GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="8">
        <location>
            <begin position="227"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif I" evidence="6">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif II" evidence="6">
        <location>
            <begin position="291"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="6">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="452" mass="50032" checksum="68903E4A26806B1D" modified="2009-05-26" version="1">MSRQIVEMTSAVGRNVPVGLSSRCRVAPTPAALRRHGYSRRVTSSTTTTTAASSSAGVGAREDASLSVADLVRPVLPSHGSTTRSPASAVFQVADLPPPVPTPSASARGAGALEVAMPPASHLLSATAAGLSLAFAFCKLKKNLDTPGRPWMDETTVGKEYDAWTDEKILEYYWGEHIHLGYYKDEDLRRGAGTLRGSRVKDFVEAKLDFVDEMLAWSRFNGTPRKVLDVGCGIGGATRHLANKFGSNTRVTGVTLSPKQARRAGELALKQGVPNAEFLVMDALEMDFPDDHFDVVWACESGEHMPDKGKYVEEMVRVLKPGGTLVIATWCQRSTPPAFTPREVVNLNYLYEEWAHPYFISINDYAMLLKGTMKMDTVETDDWTRQTIASWRHSIWVGVWDPMPVFSRPRIWYKTLRDIVCLERMRRAFGCGLMQYGMIKGTKSRKGTWSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHR9</accession>
    <name>C1MHR9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_13080</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055540.1">
        <property type="nucleotide sequence ID" value="XM_003055494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHR9"/>
    <dbReference type="STRING" id="564608.C1MHR9"/>
    <dbReference type="GeneID" id="9681065"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13080"/>
    <dbReference type="eggNOG" id="ENOG502QVUA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3647at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF81">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="68"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="231" mass="25908" checksum="BC4F641DF409F288" modified="2009-05-26" version="1">MDSPLYPDYYLKTFHYQTDGWLSTQSAEVYEVSTETLFLGRQDAMQRTALVPLSEYMRERDGAGAKLLELACGTGRFLTFVRDNYPGMDTTGLDLSPFYLIEARKNGEYWEKMRRRAAAEAMPFPDASFDVITCVYLLHELPAEARAAAAKEAARLLKPGGLLVLADSVQLGDRPRLDAHLGKFGDFNEPHYRDYISSELVSVFGPDGAGLTPWTKELCSSTKVLSFRKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI20</accession>
    <name>C1MI20_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_46288</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055053.1">
        <property type="nucleotide sequence ID" value="XM_003055007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI20"/>
    <dbReference type="STRING" id="564608.C1MI20"/>
    <dbReference type="GeneID" id="9681158"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46288"/>
    <dbReference type="eggNOG" id="KOG1015">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10263264at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16650">
        <property type="entry name" value="SP-RING_PIAS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025766">
        <property type="entry name" value="ADD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51533">
        <property type="entry name" value="ADD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="8">
        <location>
            <begin position="187"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="9">
        <location>
            <begin position="645"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="315"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="371"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="570"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="333"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="377"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="419"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="581"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="624"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="768" mass="82103" checksum="E37C43C023F76628" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI86</accession>
    <name>C1MI86_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50477</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055083.1">
        <property type="nucleotide sequence ID" value="XM_003055037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI86"/>
    <dbReference type="GeneID" id="9680430"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50477"/>
    <dbReference type="OMA" id="VCYSFRD"/>
    <dbReference type="OrthoDB" id="565672at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910472" evidence="1">
        <location>
            <begin position="26"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="194" mass="20662" checksum="BD86B752B0154F1E" modified="2009-05-26" version="1">MTTRPLAMLLALALLACFGTRHATAAFTQFTPTSAFPNRYARNYCSLIASTATDTVGASCQIDSQYGTSRGVVSMAFGEQACTVTLTGCVPGVCYSFRDHTNTVERDQVSRPTGGSGLSASLFKSISATGVSEYAHTNEGFSFTPSSSTVVISYETHSCYDYYSYRGRTEKQQCGEAIGAITEIDSGTPFSLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIJ6</accession>
    <name>C1MIJ6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Anaphase-promoting complex subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_38111</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the APC10 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055678.1">
        <property type="nucleotide sequence ID" value="XM_003055632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIJ6"/>
    <dbReference type="STRING" id="564608.C1MIJ6"/>
    <dbReference type="GeneID" id="9681101"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38111"/>
    <dbReference type="eggNOG" id="KOG3437">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FITIEFP"/>
    <dbReference type="OrthoDB" id="24948at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08366">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000122">
        <property type="entry name" value="Anaphase-promoting complex subunit 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016901">
        <property type="entry name" value="APC10/Doc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004939">
        <property type="entry name" value="APC_su10/DOC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12936">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12936:SF0">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03256">
        <property type="entry name" value="ANAPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028841">
        <property type="entry name" value="APC10_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01337">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51284">
        <property type="entry name" value="DOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DOC" evidence="8">
        <location>
            <begin position="9"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR028841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="216" mass="23021" checksum="B8C752D5272573E8" modified="2009-05-26" version="1">MAADAQVAAAPKAKVGAKAEQRDGIARPGHSEIGKLAVWSVTSAKPGNGVELLRDDCLDTYWQSDGAQPHLVNVQFQKKVRLRELALYAKYALDESYTPSKISIRAGNSFHDLREIKVVDLEEPGGWMHVSLAKDDSGGGGGGGVGGDGDDGGGGDDGECLRAFFLQIAVLSNHQNGRDTHVRQMKIFGPRTDPTALMGRGISFATPEFGQFATVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIK4</accession>
    <name>C1MIK4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_31044</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055683.1">
        <property type="nucleotide sequence ID" value="XM_003055637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIK4"/>
    <dbReference type="STRING" id="564608.C1MIK4"/>
    <dbReference type="GeneID" id="9680241"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31044"/>
    <dbReference type="eggNOG" id="KOG2549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CHEIWCK"/>
    <dbReference type="OrthoDB" id="361039at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22931">
        <property type="entry name" value="HFD_TAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.770:FF:000001">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="7">
        <location>
            <begin position="11"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="425"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="548" mass="59288" checksum="025351F70CD02D98" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIS4</accession>
    <name>C1MIS4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61699</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055183.1">
        <property type="nucleotide sequence ID" value="XM_003055137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIS4"/>
    <dbReference type="GeneID" id="9680567"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61699"/>
    <dbReference type="OMA" id="KRRDWNL"/>
    <dbReference type="OrthoDB" id="1745547at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36332">
        <property type="entry name" value="STRESS RESPONSE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36332:SF1">
        <property type="entry name" value="STRESS RESPONSE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="413" mass="43954" checksum="33E0A05894F7FB0C" modified="2009-05-26" version="1">MIKRRDWNLFRGGGGGDAGDDTSDSDPDAGRGALSGSDTDTDASLTDLTDSDAGDSDGDSDSDSDSDSKRVRKGMYNQFDDDDDASSDDDDDPDDEDDGDGNMSLSDVEETRADDAAAAAALNPKPAGGLALKCKLCPGVLCLSKDSLLRHLASKKHQKKVAKLPDGADDPMAHVKAPAGRKVPKSWKRRGDGDDDEEEKEEYDSDDDDDVDSVEGYSDGEAETHAERRARLMTQRILRAEDGDDDDDDEDVVDAVERRRAERLGLTYEGERGEKKKRDRGGRQRQRKRAKVGGAGKDGGGGGGGGGEDATPAPPAAKKGKPGKRQREAMRLAREAEEKEKAKANKAKTADVDDDDDARAPGDTRPRKNKAGEAGEGGGGAAAEGEEDAAGEDEGEGGSDERTRLEKEIKSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ18</accession>
    <name>C1MJ18_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61783</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055232.1">
        <property type="nucleotide sequence ID" value="XM_003055186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ18"/>
    <dbReference type="GeneID" id="9680303"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61783"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="166" mass="17305" checksum="B29F6043EC2F592A" modified="2009-05-26" version="1">MTSPPPAPPPAPAPRVAAEKTPDKRERERLRSARRRREATAAQREAERQRSKNRRKKMTPEQLKRQSEIRAQRRAEKAKGEGKAGGAKAKPAATGPKPDDPLAAEASADAARLAVSPSIASGGVDPMNPNGVLTAGAVGGLGAAHDISGVGSDDATHHAHGSLSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJE6</accession>
    <name>C1MJE6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50911</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055301.1">
        <property type="nucleotide sequence ID" value="XM_003055255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJE6"/>
    <dbReference type="GeneID" id="9680500"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50911"/>
    <dbReference type="OrthoDB" id="128867at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052254">
        <property type="entry name" value="CUL4-DDB1_E3_ligase_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472:SF1">
        <property type="entry name" value="DDB1 AND CUL4 ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="616" mass="66853" checksum="C93BDE81F7F1CFC3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJF0</accession>
    <name>C1MJF0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50915</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055303.1">
        <property type="nucleotide sequence ID" value="XM_003055257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJF0"/>
    <dbReference type="GeneID" id="9680502"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50915"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="711"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="554"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="613"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="664"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="727"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="815" mass="85693" checksum="A453BC33E3BA4EE9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK07</accession>
    <name>C1MK07_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_64151</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056305.1">
        <property type="nucleotide sequence ID" value="XM_003056259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK07"/>
    <dbReference type="GeneID" id="9681454"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64151"/>
    <dbReference type="OrthoDB" id="10584910at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="285" mass="32426" checksum="76176478D968E0F7" modified="2009-05-26" version="1">MVVICFLPYSSIKMRTQPVGIAPFKDLGNPSFTVNTPSHHISLNGIVLCVAKKQSGKTRFVSNLLYQLKQASCMDRIFCLSDTFDSNKKMMESREKLKRWKAFNHSLDYRITADLLEFFDPVTRQFEPPKHWLNGRKPVVGIFADDIQSSSLIGSKAFKNLCIKCRHIGAFQSGEPPIGCSIFVCVQNYTASGNEGIPKSIRGNINCCACWKSSCWTEVDLLATELSGVIPKHQILQAYDYVMNKEPDNRHNFLFIDLTPKKEHLSPFRMNYTEWLIPEKEQSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK97</accession>
    <name>C1MK97_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_14003</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055958.1">
        <property type="nucleotide sequence ID" value="XM_003055912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK97"/>
    <dbReference type="STRING" id="564608.C1MK97"/>
    <dbReference type="GeneID" id="9681679"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14003"/>
    <dbReference type="eggNOG" id="KOG0019">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GIEQHQY"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000005">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000005">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.790:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="8">
        <location>
            <begin position="28"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="693"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="705"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="718"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="103"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="731" mass="81433" checksum="EEF49847F8EF9799" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKF0</accession>
    <name>C1MKF0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40 repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_55314</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056373.1">
        <property type="nucleotide sequence ID" value="XM_003056327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKF0"/>
    <dbReference type="STRING" id="564608.C1MKF0"/>
    <dbReference type="GeneID" id="9681333"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55314"/>
    <dbReference type="eggNOG" id="KOG0271">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="21204at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16460">
        <property type="entry name" value="RING-H2_DZIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033103">
        <property type="entry name" value="DZIP3_RING-H2_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="136"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="334"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="507"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="582" mass="62172" checksum="7C5934912293A20C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKH5</accession>
    <name>C1MKH5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 13">Thymidine kinase</fullName>
            <ecNumber evidence="2 13">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_13654</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>thymidine + ATP = dTMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the thymidine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 13"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055998.1">
        <property type="nucleotide sequence ID" value="XM_003055952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKH5"/>
    <dbReference type="STRING" id="564608.C1MKH5"/>
    <dbReference type="GeneID" id="9681952"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13654"/>
    <dbReference type="eggNOG" id="KOG3125">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IPVYSND"/>
    <dbReference type="OrthoDB" id="439028at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046104">
        <property type="term" value="P:thymidine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000948">
        <property type="entry name" value="Thymidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="THYMIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441:SF0">
        <property type="entry name" value="THYMIDINE KINASE, CYTOSOLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 13" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="7 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH59374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="208" mass="23345" checksum="0B5252B0E70C0F83" modified="2009-05-26" version="1">MKYTDFAQGLNISKNTGEIHLITGPMFSGKTTELLERVSQEEALGLVVSLVKSFEDFRYSCDHIVTHDGILRTCFSVAKLNEIRSTLGDAEWRRVDIFAIDEAQFLPDLPRFCAAADSEKKKIIFAGLEGDFRREQFGKLLDLLPLCDSIFKLSAKCCSCNIRPATFTSRISPENNTAQQCIGGSDTYQTVCRSCFVRSKLFALYLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLY8</accession>
    <name>C1MLY8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_38768</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056846.1">
        <property type="nucleotide sequence ID" value="XM_003056800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLY8"/>
    <dbReference type="STRING" id="564608.C1MLY8"/>
    <dbReference type="GeneID" id="9682285"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38768"/>
    <dbReference type="eggNOG" id="KOG4183">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VGKNFTH"/>
    <dbReference type="OrthoDB" id="532500at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009668">
        <property type="entry name" value="RNA_pol-assoc_fac_A49-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14440">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06870">
        <property type="entry name" value="RNA_pol_I_A49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="502" mass="54841" checksum="47F34C0FFE2C91F2" modified="2009-05-26" version="1">MALKRGAVVEIEALASGDDGDGPFVIHNPHLPKGRFPSGTTFQAWTRDAPSDDDDSANRRAEDVIVRGRTDGVDYVGKNFLEEKPREADPCHMPTDACVYFVARVRKLSGNDVGGGGGGGVGAGATHAMAIAPVAGGAIFPIETRCHALEYDPPAVTGPVEDMDDPETRRMASARLTAAFSSQKRQRKVARVRAERAVDASTFASSSALQDALAAATANEMSAKQLSELAGANRNIPGHDVDATNPSDAFPFELFPLLDLLDRTRWKDLSEASKKPSKMKELEADGHFDAYTLSLVPKIAEGTGVPGGDKHEESRRRKLRAKSLAALDFLIKFYVHKGVVVERREKKRKGEEEIEIDSAVPKPWILLWTDESKVHPFVQRGVVDAFTELQRSEDGTLPGADEAKRYVRPKRSKDLLCMHVILMALRVCDWTLDVTALGKKMKESLKELIPHCKELGCKLSKEGTAKTGGVTTFATLPLDGTKRLGDFLPEIKRRPQAAKKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMP9</accession>
    <name>C1MMP9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_56611</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057443.1">
        <property type="nucleotide sequence ID" value="XM_003057397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMP9"/>
    <dbReference type="GeneID" id="9682406"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56611"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="5">
        <location>
            <begin position="74"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="307" mass="32842" checksum="5D73313A16907079" modified="2009-05-26" version="1">MATRAREDDVDHADENHDGNDARDARGARASTSGGSDSLRSGATAAGLGFKCANSSVSWPIDELSVFDTANIAECRVCGDVDATDRGDVRETCDCGDFTAHVHQGCMARWVETQGTRCACGKSFQSVARGLNGGDEGSVHSAHVREVIFDATSKRRRTSAFAPPTAEDEDARRAHLLLTAAYLRLTMDVPKPEDMRTLRKLAPFCDGPWNEFLRRRDEGRHRGGGLWNKIKKKFGFANTSHGGLDDDARVGDGRWSALNGDGEEGQPCEVFVPLFTRAPSRESSGGGGMSVHGGTHFAAGELVTGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN78</accession>
    <name>C1MN78_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_62696</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057056.1">
        <property type="nucleotide sequence ID" value="XM_003057010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN78"/>
    <dbReference type="GeneID" id="9682495"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62696"/>
    <dbReference type="OrthoDB" id="285793at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="435" mass="45445" checksum="23412455E3276B84" modified="2009-05-26" version="1">MDRGDWAVVADDSERTTTRPSPSPAAAGDDDDDDDAMDVGGGAKRPRPLKKKEKQELVKTLMSHGLCRVRGGGADWARILELSGLRGHTEADVAAAFNEIATEMDALASATKGILNLKKRLPGKIHKENCGCIVCKMRRRKEAEGGGGGGDDGAEGGGGGGSQDAEPTTPGSVATSQGDDDDDEFGDDDDDNDDDTDGGTGGGTGASTPAQGGGATHHDDTLQAKEELEKILDLHKSKKGRVLTATNASRLNDRLNLMQTLRNACDAVGGNLASLRLPPVRTGDIPVWWTTGVHDIGLVAAALKYGLSDWDAAREDPDLPFRDLGKDDGGDGGGGGDDAVAMDADGDAERAEKTTPTAAPRLNAPKKRPTTKALPAPRVLVRVLKVYANALRRKPWKPGSTPGTTREREGPSPKRRRGAAACPDGSPTPMEEGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNJ8</accession>
    <name>C1MNJ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55930</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057118.1">
        <property type="nucleotide sequence ID" value="XM_003057072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNJ8"/>
    <dbReference type="GeneID" id="9682557"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55930"/>
    <dbReference type="OMA" id="HKATKGH"/>
    <dbReference type="OrthoDB" id="5107at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020526">
        <property type="entry name" value="Ribosomal_cL38"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17257">
        <property type="entry name" value="DUF5323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="66" mass="7326" checksum="81BBA2530AC68F22" modified="2009-05-26" version="1">MSTLVIGAPARLVVRAAVHPKHKATKGHTKNRPKKHRPSDKVRKAVVYPEVKPEDVPPLMTVLSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNM7</accession>
    <name>C1MNM7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_55961</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057135.1">
        <property type="nucleotide sequence ID" value="XM_003057089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNM7"/>
    <dbReference type="GeneID" id="9682086"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55961"/>
    <dbReference type="eggNOG" id="KOG4373">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF104">
        <property type="entry name" value="EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="3">
        <location>
            <begin position="89"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="297" mass="31942" checksum="DE89561EDC6D7F99" modified="2009-05-26" version="1">MPPRAPGPPDDVFLVPVVTECGTCASVVACQWDGVDGNWFCRGCWLEIGGRGPDPSWPDATVVCTRDQAHAAEATRAWRAGLDDDDAEALPVGFDVEWKPNYVRGEPPNRVALLQLHARGLSVLTRLVGHATLHADILALMTHPNVILVGVGVKQDVRKLARDFPGGGGGDAAATTTTTKTTKTTTTVRVAELADVARRLGHEGGCGLKALALANDVSTSHKTKRLTMTNWEKPTLSPPEVRYGSQDASLGVDVAEKLRRSAARAGGDVARRVSRRARRDARVGRVTIRVSKRRRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNV0</accession>
    <name>C1MNV0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_38606</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056707.1">
        <property type="nucleotide sequence ID" value="XM_003056661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNV0"/>
    <dbReference type="GeneID" id="9682615"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38606"/>
    <dbReference type="OrthoDB" id="498675at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47587">
        <property type="entry name" value="OS05G0103500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47587:SF2">
        <property type="entry name" value="OS05G0103500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="337" mass="36707" checksum="729DFA679F339A7A" modified="2009-05-26" version="1">MMYNGEEIWDPDERRRIEENKSWKRSDSPTEAWDIDKERDAVMYKRESLERLLSMTRDDVPKVDRAVVCGECKTRVSRRSDEGEKDKAFLHRRQYGEGFVSLGVYKSADVDAVEDSPEDARASQWWPPRRATKCRCRGCGCVLGWRVSDNPQEIITRRLVEKLDGVEPSAAAETSGRGSSSPPSPGLPQFGSPFGAFPGGSPAFSAPPLPPLAPTDAERAAYPGLESGLARSERLGAALIKRENEELPKVRAWASELHAGAYSIRGAPTPCAEEREACVKCYEGHDGDGLKCGREVAAYDRCARAAMEAFASGKTGAAAGATTREAADSSSDDDDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNZ0</accession>
    <name>C1MNZ0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_4397</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057195.1">
        <property type="nucleotide sequence ID" value="XM_003057149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNZ0"/>
    <dbReference type="STRING" id="564608.C1MNZ0"/>
    <dbReference type="GeneID" id="9682634"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4397"/>
    <dbReference type="eggNOG" id="KOG0245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RICQVRW"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117">
        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="6">
        <location>
            <begin position="2"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="96"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="356" mass="37525" checksum="E494D77C3CD7B4C6" modified="2009-05-26" version="1" fragment="single">SNVRVAVRCRPFNAREKQLSSPCVVKMDGARTTITNPVNGTSHTFEFDHSFWSHDPSGGGRGGPTHASQETVFDELGRDLLENAWAGYNVCLVAYGQTGSGKSYSMMGGGGGGGDHAGVVPRAAREIFDRMRGDDSARVEVTMIEIYNERVKDLLNAGGGGGSTNPFAENGGGGLKIRTHPTRGPYVEGLTPCAARDYDEVVRLMDRGEKARSVASTAMNATSSRAHTIVELRISRADADGSEIRSKVSLVDLAGSERSDATGATGARLKEGAAINKSLSALGNCISALAEKGGGKKLVPYRDSALTLLLKESLGGNAKTVMIAALSPAAVNYEETLSTLRYADRARRIEGTATVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNZ5</accession>
    <name>C1MNZ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">H+-or Na+-translocating f-type, v-type and A-type ATPase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_56087</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056730.1">
        <property type="nucleotide sequence ID" value="XM_003056684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNZ5"/>
    <dbReference type="STRING" id="564608.C1MNZ5"/>
    <dbReference type="GeneID" id="9682079"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56087"/>
    <dbReference type="eggNOG" id="KOG1758">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PHQTIYR"/>
    <dbReference type="OrthoDB" id="270171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.440">
        <property type="entry name" value="ATP synthase delta/epsilon subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="entry name" value="F0F1 ATP synthase delta/epsilon subunit, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01216">
        <property type="entry name" value="ATP_synt_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="ATP SYNTHASE DELTA/EPSILON CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822:SF7">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="Epsilon subunit of F1F0-ATP synthase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP synthase F1 complex delta/epsilon subunit N-terminal" evidence="11">
        <location>
            <begin position="82"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="213" mass="23076" checksum="1D879725D06C15EE" modified="2009-05-26" version="1">MALRQAMRRLGALSSQTSTAARAFTTSAPRLEATEAQKESIKSFMDAFDQNKPIPTMDLPSTPSNFMSPEREVPATPPEKMTLNFYMPHEIQFKDAEVDQVMIPATSGDFGVLPGHVPTVAQLRPGVVSVQLNSSETQKYFVSSGFAFVHANSVTDIMAVEAIPLEQLDDAAVKKGLADFNNKLVNAKDDYEKAAAQIGIEVCGAMNHALEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP94</accession>
    <name>C1MP94_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56192</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057246.1">
        <property type="nucleotide sequence ID" value="XM_003057200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP94"/>
    <dbReference type="GeneID" id="9682220"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56192"/>
    <dbReference type="eggNOG" id="ENOG502S3SR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KYWFATS"/>
    <dbReference type="OrthoDB" id="206539at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="637"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="928"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="969" mass="103521" checksum="A9A367F43E51C387" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPG2</accession>
    <name>C1MPG2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46914</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057571.1">
        <property type="nucleotide sequence ID" value="XM_003057525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPG2"/>
    <dbReference type="STRING" id="564608.C1MPG2"/>
    <dbReference type="GeneID" id="9683391"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46914"/>
    <dbReference type="eggNOG" id="ENOG502SQ4T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ERHRTNY"/>
    <dbReference type="OrthoDB" id="568363at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="429" mass="46113" checksum="EC867CF6E808FA00" modified="2009-05-26" version="1">MASEQISFMEEPTTITTAPGPVTEAKTPKSPTVKSPKSPSVKSPGSGSMKSAGSPGAAPEDVGMMDDAAPGSPGMGGGDPYDAMAGAASEEDAASRLAQLQMQVEAQAQQLEVESKTNAELEDMLLRIEKHFKAEQVARRKAEEMVAEAESKIAAERAAKEAISAELNNVGHEAERNKALKAALSAEQGALESEKNKVMTEIEEARSDANRAAEALAKAEEAIRQEETVARLKLEAEHNAKVARLATEIDRLKEELETRTNAMGNEMMRWKVQADAAAHAVSVAKDEVMERKRELDNTKEKMDHLVEKLYIGREKGLELRGAIDFHLERHRTNYQHGRSLMPGIGGADKKKGVSSLDTARGVANTDLRSQRAKPQAKPGVERERVIRAKKKAADPDMFGAPSRDINNPGGMTGGAGYGGRGGARGMRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPR8</accession>
    <name>C1MPR8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_11584</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057998.1">
        <property type="nucleotide sequence ID" value="XM_003057952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPR8"/>
    <dbReference type="STRING" id="564608.C1MPR8"/>
    <dbReference type="GeneID" id="9683067"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11584"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HIRVCEI"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="109"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="148" mass="16066" checksum="5A2281958245E4C3" modified="2009-05-26" version="1" fragment="single">PSPQTGRFIPEKSNIWRDCVDGYHDWVKEHIAEGAPLDESDHCGDPPMLLAAGNGHTAVCELLINEGADLQQAGLMKDTPLARAANNGHYQCCKFLIEQGAEVDALDIGDNTALHWAAMRGNVEIVNLLLQNGADKTIKNKQGKIPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ39</accession>
    <name>C1MQ39_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GrpE protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_7324</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058059.1">
        <property type="nucleotide sequence ID" value="XM_003058013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ39"/>
    <dbReference type="STRING" id="564608.C1MQ39"/>
    <dbReference type="GeneID" id="9683003"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7324"/>
    <dbReference type="eggNOG" id="KOG3003">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QHELICH"/>
    <dbReference type="OrthoDB" id="201635at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.22.10:FF:000002">
        <property type="entry name" value="GrpE protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF23">
        <property type="entry name" value="GRPE PROTEIN HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="150" mass="16396" checksum="8C4096E7AC0CA56F" modified="2009-05-26" version="1" fragment="single">QVKDLNDKLLRTLADMENLRERTRRQAENAEKFAIQGFCKDLLDVADNLGRAAATVDADAIAAESDGEKLKKMLTSLHEGVLMVEKQLGSTFGKHGVEKYDPTGEDFDPNAHMALFNVPDAEKTAGTIASVTKAGYKLHDRVIRPAEVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQF1</accession>
    <name>C1MQF1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carbohydrate-binding module family 48 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_32976</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase gamma subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058117.1">
        <property type="nucleotide sequence ID" value="XM_003058071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQF1"/>
    <dbReference type="STRING" id="564608.C1MQF1"/>
    <dbReference type="GeneID" id="9683555"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32976"/>
    <dbReference type="eggNOG" id="KOG1616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1764">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TASIHPF"/>
    <dbReference type="OrthoDB" id="531008at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:001860">
        <property type="entry name" value="Sucrose nonfermenting 4-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF35">
        <property type="entry name" value="LD22662P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="190"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="454"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="508" mass="54361" checksum="0F03CC88DB200D66" modified="2009-05-26" version="1">MAQPAMYEQMVFPTRFVWAYGGKQVHLCGSFTNWLETVPMAIEPNPTGGEVFAVVCNLPPGYHQYKFIVDGEWRHDENQAFIQDPLGNVNNWLFVKKPGAANEPSPGQGIPIPQPREGGAGGGMDWIGSSMGGLQIKRNSEGVIKQPGPASSLAPSAMGIKGIAGVSDGDQDTSRARVLEFLQRHTAYELIPESNKVVVLDTKLPVRQAFHACHEQGIMAAPLWDERAQEFVGMLSAGDFMDIVRVIGPSLASSAMSEAQLDQHTIAMVREEKAAETGTSPAPLVSVRPEDSLHLVTLTLMQGRLAMAPVLSYGSHPPRGQTPTAQLLHLTNLAEVFACLVRHFRGVPSALPLFSQPIGALPIGTWTAALDASASQSTPIPGLLPVKAILPSSTVEDAFKMMPGCGALPVVDEAGRLVDVYARADVILLAAENTYRRVSLSEFTVAQALQRALPTPRAHTCTRGDTLRAVVEALSLPGVRRLVVVDANSHAVEGVVSLSDVAAFLLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQT2</accession>
    <name>C1MQT2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha N-terminal protein methyltransferase 1</fullName>
            <ecNumber evidence="5">2.1.1.244</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">X-Pro-Lys N-terminal protein methyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_16294</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54712"/>
            <dbReference type="Rhea" id="RHEA-COMP:13785"/>
            <dbReference type="Rhea" id="RHEA-COMP:13971"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138057"/>
            <dbReference type="ChEBI" id="CHEBI:138315"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54736"/>
            <dbReference type="Rhea" id="RHEA-COMP:13787"/>
            <dbReference type="Rhea" id="RHEA-COMP:13974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138059"/>
            <dbReference type="ChEBI" id="CHEBI:138318"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54724"/>
            <dbReference type="Rhea" id="RHEA-COMP:13789"/>
            <dbReference type="Rhea" id="RHEA-COMP:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138061"/>
            <dbReference type="ChEBI" id="CHEBI:138317"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. NTM1 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.244" evidence="5"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058182.1">
        <property type="nucleotide sequence ID" value="XM_003058136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQT2"/>
    <dbReference type="GeneID" id="9683250"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16294"/>
    <dbReference type="eggNOG" id="KOG3178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PVRMYCL"/>
    <dbReference type="OrthoDB" id="1298661at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071885">
        <property type="term" value="F:N-terminal protein N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000025">
        <property type="entry name" value="N-terminal Xaa-Pro-Lys N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008576">
        <property type="entry name" value="MeTrfase_NTM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753">
        <property type="entry name" value="AD-003 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753:SF0">
        <property type="entry name" value="ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05891">
        <property type="entry name" value="Methyltransf_PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016958">
        <property type="entry name" value="DUF858_MeTrfase_lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR016958-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH58133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="259" mass="29022" checksum="52A5E3C5B280A72A" modified="2009-05-26" version="1">MDDKGVSIGTNVALWKAVAAGERSADGKPLWYKKGIEYWDAVPATDDGVLGGYGHVSEQDAKDNTAFLKSTMADALKEKENGTRKLVACDCGAGIGRVTSSFLIHNFDEVDLVEPVKHFIRKAEELLSGQSAPTRYNGHKAVNFFAEPLESFTPEAGRYDVIWVQWCVGHLTDDDFEAFFRRCAIGLKPGGMIYVKENNVKDGFVLDTDDSSLTRSHKYFTHLFEDRCGFEIVKHKLQTKFPQELFQVRMYAVRPRPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR64</accession>
    <name>C1MR64_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_16665</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057876.1">
        <property type="nucleotide sequence ID" value="XM_003057830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR64"/>
    <dbReference type="STRING" id="564608.C1MR64"/>
    <dbReference type="GeneID" id="9683314"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16665"/>
    <dbReference type="eggNOG" id="KOG3140">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANKMCAL"/>
    <dbReference type="OrthoDB" id="166803at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053240">
        <property type="entry name" value="VTT_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46826">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46826:SF1">
        <property type="entry name" value="TVP38_TMEM64 FAMILY MEMBRANE PROTEIN YDJX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="3">
        <location>
            <begin position="91"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="277" mass="28874" checksum="704556E6C0036143" modified="2009-05-26" version="1">MDLVDDAKPTISTSTNENEKNDDPDSTRNAAAVAGVLPLLAFGGLVAAGAHYKDEITTFLYAFSDVVEGFGPVKGPMAFMGIYVALEILAVPAIPLTMSAGAIFGPAQGTAMVSVSATAAATISFLIARYALREKVTELARKYPKFAAVDDAIGEDSFKVVALLRLSPLLPFALSNYLYGLTSVKTKPYVLASWLGMLPGTFAYVSAGAVGRTLIEAGESAASGGGAGGEWTHAAQVLCGFGFAVLSGGYVTRLATEALKEVEDEMERVEREAAKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR71</accession>
    <name>C1MR71_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_57549</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058252.1">
        <property type="nucleotide sequence ID" value="XM_003058206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR71"/>
    <dbReference type="GeneID" id="9683319"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57549"/>
    <dbReference type="eggNOG" id="KOG1919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ACEVEFE"/>
    <dbReference type="OrthoDB" id="498383at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="3">
        <location>
            <begin position="260"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="508" mass="52513" checksum="9943C68E42A2C71B" modified="2009-05-26" version="1">MAALASAAWVRVAPRARARCAHGGGARARWATTAARAVAGVESSEGATTEKSTTRDAKATREQPEETLLRYLASAYPAHFEPLLSDDDAARGVDASIAAWDELSSHDSTSLTEIVTRASGLAAVAAAAAKGSPKQGGGEKRSRSRPDPATSSARGKAAGMFNVVLSALAMRGGDDAAATATSIALERMPARGVSPDVVSYSLTAAACVRAGDDARASEVIAAASKASGAGKRANSKKSKKASKRPGAGAAPLVVVYEDDHFAAVSKPAGILTHPTGGASVDKRSVTLVDLALDAFGDEHVSALNGADARGIVHRLDKPTTGVMVIAKTDVAHALLVTAWYQRKVQKTYWAIVEGVPGRRRPKRRGDAEGEDAETEDHLFGVVDAPADGRPAKSDWKVLEIFNLPDATCSLVEVTPHTGRKHQVRSHMGAILGAPLVGDPLYRRGKPAATPAAAAAALTADGAKPGSVMFLHATSLRLEHPVTGEPMTLSAPVPDAFEELLGALRAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR73</accession>
    <name>C1MR73_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_57551</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058254.1">
        <property type="nucleotide sequence ID" value="XM_003058208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR73"/>
    <dbReference type="GeneID" id="9683692"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57551"/>
    <dbReference type="OMA" id="AFANSHM"/>
    <dbReference type="OrthoDB" id="10427106at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="474"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="503"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="569"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="314"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="617"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="740"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="337"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="625"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="647"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="682"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="701"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="713"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="755"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="905" mass="96197" checksum="171CB5E510813E40" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRA9</accession>
    <name>C1MRA9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-phosphatidylinositol-4-phosphate 5-kinase</fullName>
            <ecNumber evidence="1">2.7.1.68</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_16190</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.68" evidence="1"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058271.1">
        <property type="nucleotide sequence ID" value="XM_003058225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRA9"/>
    <dbReference type="STRING" id="564608.C1MRA9"/>
    <dbReference type="GeneID" id="9683338"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16190"/>
    <dbReference type="eggNOG" id="KOG0229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CKVSQGE"/>
    <dbReference type="OrthoDB" id="70770at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17302">
        <property type="entry name" value="PIPKc_AtPIP5K_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="5">
        <location>
            <begin position="297"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="173"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="557"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="689" mass="74876" checksum="1A68BCEBE692BF7B" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRE5</accession>
    <name>C1MRE5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">anthranilate synthase</fullName>
            <ecNumber evidence="4">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_16051</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterotetramer consisting of two non-identical subunits: a beta subunit and a large alpha subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="4"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057912.1">
        <property type="nucleotide sequence ID" value="XM_003057866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRE5"/>
    <dbReference type="STRING" id="564608.C1MRE5"/>
    <dbReference type="GeneID" id="9683733"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16051"/>
    <dbReference type="eggNOG" id="KOG1223">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GCVGYLD"/>
    <dbReference type="OrthoDB" id="1865897at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.120.10:FF:000003">
        <property type="entry name" value="Anthranilate synthase component 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005256">
        <property type="entry name" value="Anth_synth_I_PabB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00564">
        <property type="entry name" value="trpE_most"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="10">
        <location>
            <begin position="127"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="9">
        <location>
            <begin position="340"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH57863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="632" mass="68155" checksum="C68F117EB50657DD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRS5</accession>
    <name>C1MRS5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_68276</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058560.1">
        <property type="nucleotide sequence ID" value="XM_003058514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRS5"/>
    <dbReference type="STRING" id="564608.C1MRS5"/>
    <dbReference type="GeneID" id="9683999"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68276"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="391"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="469" mass="50783" checksum="D3D113DD6511696E" modified="2009-05-26" version="1">MGSSEARLAVADRVYHARGAPAEVLAGPKCETALGWIKPVADEAAKDAEKNEDFQLPRSPGLLRERERDARWVSEDQLENGNEQIFMEEDLAARGVPEAQRHLGYRRLMGRGVERDEAEAFRDFEAAAAAGDELAAFNLGYMHMKGISTPQNFTEARRRFEHAARTNKLPAAFNGLGVLHFNGWGVERNYTAARLAFEAGAARGDPDSNFNLGAIYQNGLGVDMDAKKAVEFYEAASEAGHWRAPHVLAIAHHTGSGTDVNCTRAAELYKTFVDERLGWTRLQDDAMATLDGGPVTDDETQKTTDAAPDAWGALVKYVLLAEQGSASATSNAAWVLRKSKDAVIASSGGVLDRETFFTVAREMLERAVVMGEHESHVDLGDLHWEAVRASGGPRPFVPRSVEEGASNGGETASNEGETASNEGETATPSPSPSPPRFPPRDASPEERVYFHYRAASDAGSVEGAVNLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRU7</accession>
    <name>C1MRU7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68293</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058572.1">
        <property type="nucleotide sequence ID" value="XM_003058526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRU7"/>
    <dbReference type="GeneID" id="9684011"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68293"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="229" mass="25854" checksum="ECF56E3E8BBB89DF" modified="2009-05-26" version="1">MRSTRLALSCITQTGSPPGRDETSSRVVVVGVPGLIRHPRERVRRPLHRRALRLRRDVRLGLVVAPVLAAAVVPRVRDERPLLQLRPFVDWLAAAVAAAAPPRHRRRHQSPHLEGLPRASPANLVQGAHPHRRESVRRLRVRRRGAADETVFPSPREPRTPHRRLPSKRRHVPDDNEASPRARQHDVHAARVRQEADVAVHVRARAREHDHLLLASLEPVDGAHLEGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS37</accession>
    <name>C1MS37_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">JmjN/JmjC protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58335</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058617.1">
        <property type="nucleotide sequence ID" value="XM_003058571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS37"/>
    <dbReference type="GeneID" id="9684419"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58335"/>
    <dbReference type="eggNOG" id="KOG2131">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YRMHEDH"/>
    <dbReference type="OrthoDB" id="424465at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF6">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="149"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="386"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="485"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="512" mass="56512" checksum="C8B590F19D768AF9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS42</accession>
    <name>C1MS42_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_39930</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058620.1">
        <property type="nucleotide sequence ID" value="XM_003058574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS42"/>
    <dbReference type="GeneID" id="9684421"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39930"/>
    <dbReference type="OMA" id="MNERMAE"/>
    <dbReference type="OrthoDB" id="10692306at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF60">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="807"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="538"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="697"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="828"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="862"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="893" mass="94053" checksum="9B4375DA49015F65" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS85</accession>
    <name>C1MS85_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_17050</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Endomembrane system</location>
            <topology evidence="12">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059005.1">
        <property type="nucleotide sequence ID" value="XM_003058959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS85"/>
    <dbReference type="STRING" id="564608.C1MS85"/>
    <dbReference type="GeneID" id="9684079"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17050"/>
    <dbReference type="eggNOG" id="ENOG502RRDQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ARCGHIR"/>
    <dbReference type="OrthoDB" id="496647at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48052:SF8">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE_THREONINE-PROTEIN KINASE FLS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48052">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH57460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="821" mass="84372" checksum="795F446FB4746225" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSK2</accession>
    <name>C1MSK2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_33308</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058694.1">
        <property type="nucleotide sequence ID" value="XM_003058648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSK2"/>
    <dbReference type="STRING" id="564608.C1MSK2"/>
    <dbReference type="GeneID" id="9683792"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33308"/>
    <dbReference type="eggNOG" id="KOG0772">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KGDQYIT"/>
    <dbReference type="OrthoDB" id="10264376at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051858">
        <property type="entry name" value="WD_repeat_GAD-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017">
        <property type="entry name" value="GASTRULATION DEFECTIVE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="52"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="156"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="254"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="429"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="495"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="530" mass="58326" checksum="BB20C568B220B62C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSQ0</accession>
    <name>C1MSQ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57775</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058364.1">
        <property type="nucleotide sequence ID" value="XM_003058318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSQ0"/>
    <dbReference type="GeneID" id="9684155"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57775"/>
    <dbReference type="OMA" id="VKRRCPY"/>
    <dbReference type="OrthoDB" id="197698at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="271" mass="28137" checksum="719D0DD6FED38E98" modified="2009-05-26" version="1">MKDADAPARASLCDLLEVTRRVMAPVEANGTFWCQEVDAHQMVEWTLSELAEVEEEIRAAEDAMATATATDATDATDASDADGASSSPGATGPKSELAVAARKRVQDELGDLVFDVIMLGCMCERRFGAGNAALAGEPNTFRVSLAAAVRGAADKVKRRCPYSFGPAAGPCPSRAAEKESWTAAKRLEKAHRAGGPPPPPAPPTRRRGEDGFGSTTRFSSGDGVRSGWSAGALTACAVGMSAVAFAGGFALGGKQETRDAVKDAISGLFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTQ6</accession>
    <name>C1MTQ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_1434</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059064.1">
        <property type="nucleotide sequence ID" value="XM_003059018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTQ6"/>
    <dbReference type="STRING" id="564608.C1MTQ6"/>
    <dbReference type="GeneID" id="9684801"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_1434"/>
    <dbReference type="eggNOG" id="KOG2031">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GHHHTKM"/>
    <dbReference type="OrthoDB" id="47785at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
        <property type="term" value="F:3'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09122">
        <property type="entry name" value="PLDc_Tdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09123">
        <property type="entry name" value="PLDc_Tdp1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="11">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH56196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="520" mass="56606" checksum="1A1C3DBF6F758BAE" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTS8</accession>
    <name>C1MTS8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_40052</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059076.1">
        <property type="nucleotide sequence ID" value="XM_003059030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTS8"/>
    <dbReference type="STRING" id="564608.C1MTS8"/>
    <dbReference type="GeneID" id="9684523"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40052"/>
    <dbReference type="OMA" id="DRIKTHV"/>
    <dbReference type="OrthoDB" id="410458at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007263">
        <property type="entry name" value="DCC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052927">
        <property type="entry name" value="DCC_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33639:SF2">
        <property type="entry name" value="DUF393 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33639">
        <property type="entry name" value="THIOL-DISULFIDE OXIDOREDUCTASE DCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04134">
        <property type="entry name" value="DCC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="172" mass="18461" checksum="6FC0FD2ABCF120DE" modified="2009-05-26" version="1">MGPPAAARSPGEPTTSSKTSVVLVDGDCVLCDGFARFVSAFDARGVVLFATQQSEEGRAVLRRANAPMDLSTIVLVEHDARAEVAKDDRIKTHVKSTAILRALTALGLPLSTLGWAGLALVPRRVRDGAYDVVARYRHVVFGRKGEGGSCALPDVVVRRRMGRKIPRELLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUS6</accession>
    <name>C1MUS6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_69658</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059550.1">
        <property type="nucleotide sequence ID" value="XM_003059504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUS6"/>
    <dbReference type="STRING" id="564608.C1MUS6"/>
    <dbReference type="GeneID" id="9684990"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69658"/>
    <dbReference type="eggNOG" id="KOG1343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VASTPEW"/>
    <dbReference type="OrthoDB" id="564793at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF10">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="367"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Histone deacetylase" evidence="3">
        <location>
            <begin position="454"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="237"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="712" mass="73852" checksum="C686B73B36C942C9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUW8</accession>
    <name>C1MUW8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_58960</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059263.1">
        <property type="nucleotide sequence ID" value="XM_003059217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUW8"/>
    <dbReference type="GeneID" id="9685014"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58960"/>
    <dbReference type="OMA" id="DWACAKC"/>
    <dbReference type="OrthoDB" id="29221at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="128"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="341" mass="36117" checksum="C3E3E8E931343E1B" modified="2009-05-26" version="1">MPRTRGGADTTPTKDPPAAKKTPNTAKKTPAATAKKADAKVDDVAEAKAPPTTESASKPPKAEGKRKPRTPKGNRPVTAKAPAEKATELATPGVTKKKKKKVRKPKTPTSGGGSMAPKSSAGGDGKWKPGDWACAKCGMHNFRGKDACFRCKYARANSLKAASAESAMAYLKKREEDGSGAVGAAVDAVQHQWLMKHHGMNLVNDACFDVYVPYVKQLDDAHKWQILKAARLAVTRAQRLVDALADTPETAAPTKKKEPPRRDGGGGGGGGGDGSAKKKKKKKKNKSGGGNGGGDEGKAGTPQEKSKKREREEDGGGDKKEHKSKKAKKAKKEKRDKKDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVA4</accession>
    <name>C1MVA4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_44443</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059340.1">
        <property type="nucleotide sequence ID" value="XM_003059294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVA4"/>
    <dbReference type="STRING" id="564608.C1MVA4"/>
    <dbReference type="GeneID" id="9685073"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44443"/>
    <dbReference type="eggNOG" id="KOG2265">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RDVECSL"/>
    <dbReference type="OrthoDB" id="515366at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF18">
        <property type="entry name" value="NUDC DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="1">
        <location>
            <begin position="16"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="149" mass="16411" checksum="81B57B0D99C9DD54" modified="2009-05-26" version="1">MADQLAPSKRHAHEHEGRVVYEWDQTLDELNLYVPVPKGIGAKMLDVDVGADALKFGIRGNPPYLAHDLSHSVKTSDCFWTLEDGELHVTLQKMKRGKPWDALFKGHEGGLDAFAEREERERLMKGAGAAFNGEAPSADAFMGGIKHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVC0</accession>
    <name>C1MVC0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_6677</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 10">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 10">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059347.1">
        <property type="nucleotide sequence ID" value="XM_003059301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVC0"/>
    <dbReference type="STRING" id="564608.C1MVC0"/>
    <dbReference type="GeneID" id="9685082"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6677"/>
    <dbReference type="eggNOG" id="KOG0323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TIGECAY"/>
    <dbReference type="OrthoDB" id="498739at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="7">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="136" mass="15469" checksum="60FEE20EC542304E" modified="2009-05-26" version="1" fragment="single">KLRPRAREFLRAASAMCQLYVYTMGDKNYAREMAKILDPTGELFNGRVIANSDSTCSRTKDLDIVLGAEGSVLIVDDTDRVWPHNLANLIRIDRYHFFPQSAAGFRQPGRSVLERAWKDEGANGDREQLRDVLRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVX8</accession>
    <name>C1MVX8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Signal recognition particle subunit SRP72</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_47730</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SRP72 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059829.1">
        <property type="nucleotide sequence ID" value="XM_003059783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVX8"/>
    <dbReference type="STRING" id="564608.C1MVX8"/>
    <dbReference type="GeneID" id="9685554"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47730"/>
    <dbReference type="eggNOG" id="KOG2376">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NDMKVLA"/>
    <dbReference type="OrthoDB" id="5421607at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013699">
        <property type="entry name" value="Signal_recog_part_SRP72_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026270">
        <property type="entry name" value="SRP72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094:SF9">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08492">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038922">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="Signal recognition particle SRP72 subunit RNA-binding" evidence="10">
        <location>
            <begin position="633"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="610"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="617"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="657"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="667"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="700"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="731"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH55781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="740" mass="77207" checksum="67A5BF08F503AE88" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWK9</accession>
    <name>C1MWK9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">MICPUCDRAFT_908</name>
    </gene>
    <organism evidence="25">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18 20">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="19">Forms DNA polymerase zeta with REV7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059649.1">
        <property type="nucleotide sequence ID" value="XM_003059603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWK9"/>
    <dbReference type="STRING" id="564608.C1MWK9"/>
    <dbReference type="GeneID" id="9685379"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_908"/>
    <dbReference type="eggNOG" id="KOG0968">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NAQYYIT"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05534">
        <property type="entry name" value="POLBc_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000007">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000002">
        <property type="entry name" value="DNA polymerase zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="15 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13 20" id="KW-0408">Iron</keyword>
    <keyword evidence="14 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="11 20" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="22">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="21">
        <location>
            <begin position="194"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="23">
        <location>
            <begin position="713"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="24">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="24">
        <location>
            <position position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00066055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EEH55601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="793" mass="85685" checksum="3AD5DCEEA3077C13" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWL3</accession>
    <name>C1MWL3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Platz-like transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59161</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059942.1">
        <property type="nucleotide sequence ID" value="XM_003059896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWL3"/>
    <dbReference type="STRING" id="564608.C1MWL3"/>
    <dbReference type="GeneID" id="9685381"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59161"/>
    <dbReference type="eggNOG" id="ENOG502R0ZN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CANHHAS"/>
    <dbReference type="OrthoDB" id="1908108at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006734">
        <property type="entry name" value="PLATZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31065:SF1">
        <property type="entry name" value="OS09G0116050 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31065">
        <property type="entry name" value="PLATZ TRANSCRIPTION FACTOR FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04640">
        <property type="entry name" value="PLATZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="447" mass="45297" checksum="E9B9A86C68DD7173" modified="2009-05-26" version="1">MKNGKVALPADLAWVQDLVASAFFEPCANHHASAGKGELANLFCASTSKTYCASCAGGRDVVQRNEKTRSLTSSSLLSLLSLRPPQVRRSSYHNVVRVQDVCALMDVSAIQTYVINSARVVFLRRVLYTGKGKDGEEKKASSKPGKEPKSKARHSACAHCNRLLQTENCDFCSIACKVRAGADMRASPASEAAARLAALNVPKAEGRGGGGGDAASKAKRGKEGEPGAGGGTAAAKREKKEKEGDAAARNAATAGLAGVKKEGSKGKRKADADADAGGEGTSPRTPASAKRPGAAAADEKKAGSSSRSRGKSSSGGGSTKASRAATTTTTTTTTTATTTTTLTTTPAKRGRDASGQTPSKSEHRAGTGPNTPTAVGDAGARPRGADAPRTASAGAANAAGKKSKSVFAAAKEEDGSERGSAAAAAAAAALFVSSKRRKPSKPKRAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWS3</accession>
    <name>C1MWS3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_59233</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059678.1">
        <property type="nucleotide sequence ID" value="XM_003059632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWS3"/>
    <dbReference type="STRING" id="564608.C1MWS3"/>
    <dbReference type="GeneID" id="9685414"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59233"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SYERTHC"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061629">
        <property type="term" value="F:RNA polymerase II-specific DNA-binding transcription factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF53">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 4 INHIBITOR D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1062"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1095"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="266"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="476"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="521"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="675"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="732"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="978"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="376"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="480"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="492"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="521"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="542"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="982"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="996"/>
            <end position="1012"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1137" mass="120676" checksum="0EA1ADC2141BF562" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWX3</accession>
    <name>C1MWX3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_34157</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the costars family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059997.1">
        <property type="nucleotide sequence ID" value="XM_003059951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWX3"/>
    <dbReference type="GeneID" id="9685160"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34157"/>
    <dbReference type="eggNOG" id="KOG3376">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WIPSTIM"/>
    <dbReference type="OrthoDB" id="9871914at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032970">
        <property type="term" value="P:regulation of actin filament-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1540:FF:000002">
        <property type="entry name" value="costars family protein ABRACL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1540">
        <property type="entry name" value="Costar domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044302">
        <property type="entry name" value="Costars"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027817">
        <property type="entry name" value="Costars_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038095">
        <property type="entry name" value="Costars_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46334">
        <property type="entry name" value="COSTARS FAMILY PROTEIN ABRACL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46334:SF1">
        <property type="entry name" value="COSTARS FAMILY PROTEIN ABRACL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14705">
        <property type="entry name" value="Costars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01283">
        <property type="entry name" value="Costars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Costars" evidence="2">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="82" mass="9032" checksum="12E8D299FD14E982" modified="2009-05-26" version="1">MGLDVEGEVKQLVEEIKRLGGNVDGKTTVKFGVLFADDRCANIFEALVGTLRAAKKRKVIHFDGEMLLQGAHDHVDVVLLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX33</accession>
    <name>C1MX33_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_60013</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Mediator complex subunit 21 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060328.1">
        <property type="nucleotide sequence ID" value="XM_003060282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX33"/>
    <dbReference type="STRING" id="564608.C1MX33"/>
    <dbReference type="GeneID" id="9686058"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60013"/>
    <dbReference type="eggNOG" id="KOG1510">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GQAADHC"/>
    <dbReference type="OrthoDB" id="526653at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.10">
        <property type="entry name" value="Mediator complex, subunit Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021384">
        <property type="entry name" value="Mediator_Med21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381:SF0">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381">
        <property type="entry name" value="RNA POLYMERASE II HOLOENZYME COMPONENT SRB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11221">
        <property type="entry name" value="Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="138" mass="14972" checksum="C2DC1746C385A5DE" modified="2009-05-26" version="1">MADIVTELQESVDRLNEAFYNSVGVLQRDAKPASVVEGADPSEGVDEAQVREMARSVMDESRKIDELASALPPVDLDADAQLARIAKLAEEDHALGEELRAELTRAKKTLTKVTAAFEAVTDDILLTREETTGGDEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXJ7</accession>
    <name>C1MXJ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein 70</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_45719</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 (TC 1.A.33) family. HSP110/SSE subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060408.1">
        <property type="nucleotide sequence ID" value="XM_003060362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXJ7"/>
    <dbReference type="STRING" id="564608.C1MXJ7"/>
    <dbReference type="GeneID" id="9686142"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45719"/>
    <dbReference type="eggNOG" id="KOG0103">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WEQSPEI"/>
    <dbReference type="OrthoDB" id="434160at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000171">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000004">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="503"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="753"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="514"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="783"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00061090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="819" mass="88423" checksum="BF11D092C4BE5D69" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXS8</accession>
    <name>C1MXS8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_69195</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060448.1">
        <property type="nucleotide sequence ID" value="XM_003060402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXS8"/>
    <dbReference type="STRING" id="564608.C1MXS8"/>
    <dbReference type="GeneID" id="9686183"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69195"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAPNACK"/>
    <dbReference type="OrthoDB" id="533036at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053209">
        <property type="entry name" value="Gramillin-biosynth_MTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643:SF2">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="70"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="516" mass="54403" checksum="7307ADE7EA9A6928" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY69</accession>
    <name>C1MY69_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Glutathione reductase</fullName>
            <shortName evidence="14">GRase</shortName>
            <ecNumber evidence="14">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_45738</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 14">
            <text>2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="14"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060818.1">
        <property type="nucleotide sequence ID" value="XM_003060772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY69"/>
    <dbReference type="STRING" id="564608.C1MY69"/>
    <dbReference type="GeneID" id="9686255"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45738"/>
    <dbReference type="eggNOG" id="KOG0405">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NYHKLAD"/>
    <dbReference type="OrthoDB" id="5956163at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000051">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006324">
        <property type="entry name" value="GSHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01424">
        <property type="entry name" value="gluta_reduc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="3 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="5 14" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="16">
        <location>
            <begin position="5"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="15">
        <location>
            <begin position="356"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="190"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="52"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH55587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="478" mass="50493" checksum="CEE5E48E6B5B7123" modified="2009-05-26" version="1">MEYDYDVFTIGGGSGGVRAARMSSTAGAKVGLVELPYAAISSATAGGLGGTCVIRGCVPKKLLVYGAAFEAEFRDAVGFGWDHGESAPTFSWERLIAAKTTEIERLNGIYGRILDNAGVDKFEGVGKVTGPHEVTVTTVDGVATKYSAKTILLAPGGRAWYPSIPGADLGITSDEALAFEKQPKRVLVIGGGYIAVEFAGIFAGLGSDVEIMYRADLPLRGFDEEVRQTVANNLEGRGIVVRDGVNPLKISKNDDGSLSVETDAAGVIETDCVMWATGRVPNTDRPDLGLKEIGVELDAKGAVVVDEYSKTTVDSIYAVGDVTNRVNLTPVALMEGMAFKDTVVRGIPTKPDYENIPSAVFCQPPVATVGMTEAQAIAAGHTCDVYTSTFTPMKISLAGRVEKAFMKLIVDVDTDKVIGCHMVGPDSAEIMQGLGIALKCGATKKQFDSCVGIHPSSAEEFVTMRDATRRVGPNAEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY71</accession>
    <name>C1MY71_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60425</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060820.1">
        <property type="nucleotide sequence ID" value="XM_003060774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY71"/>
    <dbReference type="GeneID" id="9686257"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60425"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="73" mass="8069" checksum="E0DB48067F3012E1" modified="2009-05-26" version="1">MSGTADVVWTSGTATAGATLTAEEAKWELPKKRAVPRTKEERGPILKFTELVTKVRSIHWFPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY81</accession>
    <name>C1MY81_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_40759</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060236.1">
        <property type="nucleotide sequence ID" value="XM_003060190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY81"/>
    <dbReference type="STRING" id="564608.C1MY81"/>
    <dbReference type="GeneID" id="9685969"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40759"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="507940at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="128"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1013" mass="106375" checksum="B61D2D23DE5D08C1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYH6</accession>
    <name>C1MYH6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_41129</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060831.1">
        <property type="nucleotide sequence ID" value="XM_003060785.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MYH6"/>
    <dbReference type="GeneID" id="9685968"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41129"/>
    <dbReference type="OrthoDB" id="20774at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="2">
        <location>
            <begin position="47"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="954"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1230"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1297"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1434"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1767"/>
            <end position="1790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1849"/>
            <end position="1881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1911"/>
            <end position="1933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="965"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1300"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1316"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1332"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1437"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1453"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1469"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1769"/>
            <end position="1787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1911"/>
            <end position="1924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1949" mass="203226" checksum="44631DC94A775E25" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYP1</accession>
    <name>C1MYP1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_59972</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060309.1">
        <property type="nucleotide sequence ID" value="XM_003060263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYP1"/>
    <dbReference type="STRING" id="564608.C1MYP1"/>
    <dbReference type="GeneID" id="9685747"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59972"/>
    <dbReference type="OMA" id="NEMRGIR"/>
    <dbReference type="OrthoDB" id="10066206at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031632">
        <property type="entry name" value="SVIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15811">
        <property type="entry name" value="SVIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0519">Myristate</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="26"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="78" mass="8722" checksum="2AE527FE99E8A3DD" modified="2009-05-26" version="1">MGCCGSKQAKEPPGAYEARREQMLAAASKRNAENEMRGIRNPKAAAKLREAQSNRSESQRGWSAAEDRRQESIAKDWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZQ6</accession>
    <name>C1MZQ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60816</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061261.1">
        <property type="nucleotide sequence ID" value="XM_003061215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZQ6"/>
    <dbReference type="STRING" id="564608.C1MZQ6"/>
    <dbReference type="GeneID" id="9686434"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60816"/>
    <dbReference type="OMA" id="RIRESVW"/>
    <dbReference type="OrthoDB" id="10260455at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22961">
        <property type="entry name" value="DD_TEX55-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039879">
        <property type="entry name" value="EFC10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21847">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21847:SF1">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="15"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="221"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="289" mass="31670" checksum="ADCD2A8FE961330B" modified="2009-05-26" version="1">MGGEAKPLPPPRSQYHAERIRDVFTQLDVNGKGILSFDEIRLGLEREGFDWVRLASESFPSAMTLRAIRPRATSPSSASRRVGASLVAVPLPSPCPFWMRRPVPRRRRLTAPPRPPPKKTPQSLANLDGKKVTRAIALEASSAGHETVDFDAFWEFCIMSGEKPGVDPVLDAHAYLTEHKVVAIVEGMTAALMVAKPEDVKPFLVERLERLKASGTPVNHFTDEDLATMFDVFDVSRHGAITAAQCNRALKALTGRDGEVRGGVDESVATVTMRAFIKHARAALDDHCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZX1</accession>
    <name>C1MZX1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_48143</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LIMR family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061293.1">
        <property type="nucleotide sequence ID" value="XM_003061247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZX1"/>
    <dbReference type="STRING" id="564608.C1MZX1"/>
    <dbReference type="GeneID" id="9686732"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48143"/>
    <dbReference type="eggNOG" id="KOG2296">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="203099at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051584">
        <property type="entry name" value="GPCR-associated_LMBR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355:SF0">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="838"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="546"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="669"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="571"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="596"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="677"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="715"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="959" mass="104584" checksum="523F410E436A0C45" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N089</accession>
    <name>C1N089_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_41486</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM161 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH55004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061354.1">
        <property type="nucleotide sequence ID" value="XM_003061308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N089"/>
    <dbReference type="GeneID" id="9686524"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41486"/>
    <dbReference type="OMA" id="IAWYEVK"/>
    <dbReference type="OrthoDB" id="784140at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019395">
        <property type="entry name" value="Transmembrane_161A/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13624:SF6">
        <property type="entry name" value="EMEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13624">
        <property type="entry name" value="RE42071P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10268">
        <property type="entry name" value="Tmemb_161AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="470" mass="48996" checksum="582237365A2078DF" modified="2009-05-26" version="1">MAIIASTPENDAAVLATLPYLLLTIAFTFLAVVRKSVSLSLMEGLTCYILPETDEERWRARIAKATHEKKSSESKRRAKGARAPPAGNIDELGENSIAAIAMTKNQLILKPFWSHVDRLVFFACLVIVHCVAREVHAFVVASDGGAGSDAEGTTTTTTTNVLLAPLAAFSAVSAMRALVRAAIDPASTPAVERHVAVAAGFIGFAFSLVFLLSSPAFARAFEVAETARLTAGATLAETRAFGMEIVTLAEMQVCVALSALAGFINAALFAPATRVDAPSWDEGRGFVGASVARATCLRVAITIPFVAMIAWFDPLMRDPLGLSESALATAKAASLVVAGAALLLATPSLTQGFLDGAIITWYEVQHDGIALDASAALASRNAVRQKLMVTNRLACKVATQAAAPAALFVSCGALLLAEGDGAGFSVLNRIAPAVAWRTIASYVGWWSCASWAFTTCASIAGHNVGAGALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0B0</accession>
    <name>C1N0B0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50952</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH53994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061364.1">
        <property type="nucleotide sequence ID" value="XM_003061318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0B0"/>
    <dbReference type="GeneID" id="9687042"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50952"/>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317">
        <property type="entry name" value="BLR8090 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317:SF1">
        <property type="entry name" value="ZINC-RIBBON DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="24"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="106"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="170" mass="19250" checksum="851459593D6C38C5" modified="2009-05-26" version="1">MSPKGTGKPFIEWCAENGERGEKLLKEYCDADRGAAEVAKGSNYRALWKCSSAGCGHEWRAQVGTRTLSDRPHGCPKCNPGGSNGVTPTDNFLTWCAQNGRRGAELLREYRDPKKLPDEVKKGSNYEALWKCAKCKHRWRTKMNNRTRRVRPIRCPQCNPPGATKRRKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0C5</accession>
    <name>C1N0C5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_11558</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTH2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061610.1">
        <property type="nucleotide sequence ID" value="XM_003061564.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0C5"/>
    <dbReference type="STRING" id="564608.C1N0C5"/>
    <dbReference type="GeneID" id="9686810"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11558"/>
    <dbReference type="eggNOG" id="KOG3282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CRQTLNN"/>
    <dbReference type="OrthoDB" id="497691at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1490.10:FF:000002">
        <property type="entry name" value="Peptidyl-tRNA hydrolase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649:SF11">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="118" mass="12304" checksum="E03239C3516067D3" modified="2009-05-26" version="1" fragment="single">EMKMVLVVDASLEMGAGKVAAQCAHAALGAYQAIEHVPSQRASLKRWESEGQKKICLRVDGADALAALAGKAKEKGLAHYVVRDAGRTQVAAGSRTVLAIGPAPEMAINEITGGLRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0J3</accession>
    <name>C1N0J3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_62856</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061649.1">
        <property type="nucleotide sequence ID" value="XM_003061603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0J3"/>
    <dbReference type="STRING" id="564608.C1N0J3"/>
    <dbReference type="GeneID" id="9686840"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62856"/>
    <dbReference type="eggNOG" id="ENOG502QUPE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YFKEAFC"/>
    <dbReference type="OrthoDB" id="2020161at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019275">
        <property type="entry name" value="DUF2301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36716">
        <property type="entry name" value="F3H9.20 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36716:SF2">
        <property type="entry name" value="F3H9.20 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10063">
        <property type="entry name" value="DUF2301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="324" mass="34129" checksum="9A0046EC7D06E8BF" modified="2009-05-26" version="1">MTTARASIARLATIAAPPAASRRRAPTARAPAARATRRRAPALAAPRARSRSLASSSSESKSRHRRGGLDGVATRAVESSSDAPGSDASSYVIPGEPAYPGLYCDWSVTPTDVAEVWSYRVSLSSVALSVLACSAAAFAPDAPVNLNAAYFTGAGSLGVALTLIHMYVDPIKKAMQAMWLAGFIGSVGIAATHPDVSVPAFVATHPAAVWLVGPMFAALTGVAFKEGMCYGKAECAALFFVVPATLLGHLTGVGSEGFEKGAIVAWCALIAAFAARKYTQEVKDDIGDKSVFIFNDLSEEEKRAWTMRARERDPVRFARMMGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0N0</accession>
    <name>C1N0N0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_20651</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061671.1">
        <property type="nucleotide sequence ID" value="XM_003061625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0N0"/>
    <dbReference type="STRING" id="564608.C1N0N0"/>
    <dbReference type="GeneID" id="9687110"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20651"/>
    <dbReference type="eggNOG" id="KOG0273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GENQPIK"/>
    <dbReference type="OrthoDB" id="1367865at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000218">
        <property type="entry name" value="WD40 repeat-containing protein HOS15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045183">
        <property type="entry name" value="Ebi-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846:SF2">
        <property type="entry name" value="F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="82"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="123"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="206"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="248"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="299"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="375" mass="40688" checksum="7481327D8B028FDE" modified="2009-05-26" version="1">MDDDGGDDDAAARAAIAIKPEEVTTLRGHTSEVFICAWSPAGDVLASGSGDATARMWTVPAGPSGRDAAKPAREPLGDANDWNNKSKDVTTLDWNGDGSLLATGSYDGLARVWDANGNLVNSLCAHRGPIFSLKWNKKGDYLLSGSVDKTAIVWDAKTGEAKQQFAFHTAPTLDVDWRNNVSFATSSMDNMIYVCKLGETKPIKAFKGHKDEVNAIKWDPTGTLLASCSDDYSAKVWSLKQDRCVHDFTEHAKEIYTIKWSPTGPGTNNPDLPLTLATASYDATIKLWDVEEGKCMHTLRAHSDPVYSVAFSPDGKYVASGSFDKRLHVWDAKRGTLVRTHDGGGGIFEVCWNKDGSKLAACYSDNTVSVLDFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0V1</accession>
    <name>C1N0V1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_41621</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061456.1">
        <property type="nucleotide sequence ID" value="XM_003061410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0V1"/>
    <dbReference type="GeneID" id="9687141"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41621"/>
    <dbReference type="eggNOG" id="ENOG502QVVW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RNENDAH"/>
    <dbReference type="OrthoDB" id="406981at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017095">
        <property type="term" value="F:heparan sulfate 6-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010635">
        <property type="entry name" value="Heparan_SO4-6-sulfoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12812">
        <property type="entry name" value="HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12812:SF0">
        <property type="entry name" value="HEPARAN-SULFATE 6-O-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="82"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="535"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="754"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="124"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="761"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="785"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="825"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="855" mass="92507" checksum="E8C5B0EB7FBE3CF4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1A9</accession>
    <name>C1N1A9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_63049</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBR family. Ariadne subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="4"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061780.1">
        <property type="nucleotide sequence ID" value="XM_003061734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1A9"/>
    <dbReference type="STRING" id="564608.C1N1A9"/>
    <dbReference type="GeneID" id="9687219"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63049"/>
    <dbReference type="eggNOG" id="KOG1815">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EGWPCER"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20346">
        <property type="entry name" value="BRcat_RBR_ANKIB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22583">
        <property type="entry name" value="Rcat_RBR_ARI7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1750:FF:000027">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000019">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045840">
        <property type="entry name" value="Ariadne"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048962">
        <property type="entry name" value="ARIH1-like_UBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19422">
        <property type="entry name" value="Ariadne"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21235">
        <property type="entry name" value="UBA_ARI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="118"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="122"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH54410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="535" mass="60011" checksum="05722E90447452D0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1E2</accession>
    <name>C1N1E2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_51368</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL38 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061801.1">
        <property type="nucleotide sequence ID" value="XM_003061755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1E2"/>
    <dbReference type="STRING" id="564608.C1N1E2"/>
    <dbReference type="GeneID" id="9687240"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51368"/>
    <dbReference type="eggNOG" id="KOG3499">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RCHRFIY"/>
    <dbReference type="OrthoDB" id="10258478at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022618">
        <property type="term" value="P:protein-RNA complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.90:FF:000001">
        <property type="entry name" value="60S ribosomal protein L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002675">
        <property type="entry name" value="Ribosomal_eL38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038464">
        <property type="entry name" value="Ribosomal_eL38_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01781">
        <property type="entry name" value="Ribosomal_L38e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="69" mass="7787" checksum="B71E04BC4267AB4C" modified="2009-05-26" version="1">MPKQIHEIKDFLLTARRKDAKSVKIKKTGGKTKFKVRCSKYLYTLVVSDGDKADKLKQSLPPGLQVQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1J4</accession>
    <name>C1N1J4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_63118</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061568.1">
        <property type="nucleotide sequence ID" value="XM_003061522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1J4"/>
    <dbReference type="STRING" id="564608.C1N1J4"/>
    <dbReference type="GeneID" id="9687272"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63118"/>
    <dbReference type="OrthoDB" id="298344at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040221">
        <property type="entry name" value="CDCA7/CDA7L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018866">
        <property type="entry name" value="Znf-4CXXC_R1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31169">
        <property type="entry name" value="OS05G0300700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31169:SF34">
        <property type="entry name" value="ZINC-FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10497">
        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Zinc-finger" evidence="11">
        <location>
            <begin position="129"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="21"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="179"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH54198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="217" mass="24686" checksum="661F547CF0C8CCCC" modified="2009-05-26" version="1">MNDFERAREVRIEENKRRMREMGITTLSEKLERATETRAPTQRKPSKPKAFVPVAERRRSTRERATVDYAAQVNALNAFDSDSDSDDVGPRKRARRAPAEKRVRKKILFSSADAASSAARRYAVGGRVYDSELGVTCHWCRQKTVEPHVHCSNESCRRGNPIAFCGRCLRNRHGEDVEARRASLSRSPRPSQSSPLKHRHVSLTSSTHSRHVISHDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N290</accession>
    <name>C1N290_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_51893</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062250.1">
        <property type="nucleotide sequence ID" value="XM_003062204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N290"/>
    <dbReference type="STRING" id="564608.C1N290"/>
    <dbReference type="GeneID" id="9687689"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51893"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="STLCVHI"/>
    <dbReference type="OrthoDB" id="1750190at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="118"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="210" mass="22978" checksum="07588280EE486577" modified="2009-05-26" version="1">MDDYPQCETCGARFYYPAKLAEHANVHSGTTPFRCEHDGCEEAFPTRDRLRTHAQKHDAKHECALCGKRFQTAGASRRSTRVQRLNDRRVAPRVRPSLASPSRVLRSHAMTHTTSRPHACPHEGCGKAFKTEKAVASHARTHTGEKPYRCTFGACERAFSSQGEFSRHRIKTHGVRLRNAQPAAGVGDVGGGFVGVGVGADEVLVAGVCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2A5</accession>
    <name>C1N2A5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51910</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062054.1">
        <property type="nucleotide sequence ID" value="XM_003062008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2A5"/>
    <dbReference type="GeneID" id="9687699"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51910"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="262" mass="28414" checksum="5DCBF78912AEA8B1" modified="2009-05-26" version="1">MAPPRSDADDFREVSSSASRRDATTATRLSVADTRVRQDRFADTTRRAPRPHARDDDRGGRRRGGPPRTPRGRRVRLSPVRRAVHRPPSPSPLVRSTTPPPTSIDRHRPTRPTPPSSPPPSVPVDDASPGDVTRRASPADFVRIAQHLASDVAALVETAGADDARGVEAATHAIVRSCASSASVSATTPNAADANARRIEQGLRRLLAAIDAESRAASCDLRTLLDELVTYVQSGVMLSRKSEVRSIHWFPYDRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3N4</accession>
    <name>C1N3N4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_48580</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062644.1">
        <property type="nucleotide sequence ID" value="XM_003062598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3N4"/>
    <dbReference type="STRING" id="564608.C1N3N4"/>
    <dbReference type="GeneID" id="9687846"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48580"/>
    <dbReference type="eggNOG" id="KOG0045">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF423">
        <property type="entry name" value="LEUCINE-RICH REPEAT PROTEIN (LRRP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="3">
        <location>
            <begin position="6"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" evidence="1 2">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" evidence="1 2">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="active site" evidence="1 2">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="461" mass="51396" checksum="FF602B80FAB2A4AC" modified="2009-05-26" version="1">MRYFPDMHDEDWEEQDCTLFYRPTKQSSSLACDKRSGGWTVLEWTCHPLRPDVEVKDDGHEKRWLQPYVKEDRGKTVKTRGVSPGRGQGLADVPSLCLWNTISPNDLNQGSVANCYMISTFAALAEWPGAIKKLFRKTKGADEMPRSNTANEYTITLYDLESAPVAREVDVVVNERLAVDVDSGDKLGVATSDCAELWPCYLEKALVAHCGGWNAIGHRGNEGEVLRILTRCRNAYNFTLKDFARCGNIAGAKRGNRVQKRNGEGRYRIPWPSANGKPVVQPKTQDGCIDALYAYDKANYPMCCSAMRDGNTAATLADGFIDNHAYTLIRVEKNVAGSGIDMLLVRNTWGRGELTRGRFVDDGPGWKKHPEIQKALRPVFEDDGAFWVEKSEFFEYVDSVCVLALDMTTFVKSSYKPTPMLKLCPQVVDASVAAARAKAEDARKAAAERARRSNVTINLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4H3</accession>
    <name>C1N4H3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_9326</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartyl/asparaginyl beta-hydroxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062998.1">
        <property type="nucleotide sequence ID" value="XM_003062952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4H3"/>
    <dbReference type="GeneID" id="9688231"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9326"/>
    <dbReference type="eggNOG" id="KOG3696">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAFASAY"/>
    <dbReference type="OrthoDB" id="438431at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007803">
        <property type="entry name" value="Asp/Arg/Pro-Hydrxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051821">
        <property type="entry name" value="Asp/Asn_beta-hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46332:SF5">
        <property type="entry name" value="ASPARTATE BETA-HYDROXYLASE DOMAIN CONTAINING 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46332">
        <property type="entry name" value="ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05118">
        <property type="entry name" value="Asp_Arg_Hydrox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aspartyl/asparaginy/proline hydroxylase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="131" mass="13893" checksum="3D74800D26A8DD99" modified="2009-05-26" version="1" fragment="single">FGSAYLSRLAPGTTIASHHGPTNARARCHLGIRVPTRGAAAGGAGGVSPACVLKVADESTTWREGEALLFDDSFEHHAEYRKRDDAECEGEGGGGGRSRVGPTRVVLVVDLWHPRLTRADRDALGVMYPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4X5</accession>
    <name>C1N4X5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_11624</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062869.1">
        <property type="nucleotide sequence ID" value="XM_003062823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4X5"/>
    <dbReference type="STRING" id="564608.C1N4X5"/>
    <dbReference type="GeneID" id="9688512"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11624"/>
    <dbReference type="eggNOG" id="KOG0226">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RTHAMAE"/>
    <dbReference type="OrthoDB" id="1749473at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12383">
        <property type="entry name" value="RRM_RBM42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034215">
        <property type="entry name" value="RBM42_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF11">
        <property type="entry name" value="RNA-BINDING PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="25"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="106" mass="12140" checksum="8BF2D13D4655C4AA" modified="2009-05-26" version="1" fragment="single">KPVYRSAAGDRWQDKTLGDWPENDYRIFVGDLGTEVSDDHLARAFGKYASFQKARVVKDKTTQKSRGFGFVSFMDSADYSSAMREMNGKYIGNRPCKLKKSDWAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4Z8</accession>
    <name>C1N4Z8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein WDR12 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_21888</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat WDR12/YTM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063083.1">
        <property type="nucleotide sequence ID" value="XM_003063037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4Z8"/>
    <dbReference type="STRING" id="564608.C1N4Z8"/>
    <dbReference type="GeneID" id="9688321"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21888"/>
    <dbReference type="eggNOG" id="KOG0313">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DHKYVEF"/>
    <dbReference type="OrthoDB" id="10251381at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03029">
        <property type="entry name" value="WDR12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012972">
        <property type="entry name" value="NLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028599">
        <property type="entry name" value="WDR12/Ytm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855:SF11">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN WDR12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855">
        <property type="entry name" value="WD40 REPEAT PROTEIN 12, 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08154">
        <property type="entry name" value="NLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NLE" evidence="9">
        <location>
            <begin position="10"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="140"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="197"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="268"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="354"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH53022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="441" mass="46914" checksum="112F94D8B7A038CB" modified="2009-05-26" version="1">MGSTGEETQITCKFVTRLPEKYRISPTPFAVPGKLTRYGLSEVINHLLALDPPKPFDFLVDGELVRTSLEKLLLRKGVSAESTLEVEYIPAVGPPSEEATGKHDDWVAGVCGSWGGAIATASYDGTTRLYSPKGKHLVTLDGHAQPVVAVTLLPPTEDDGNGCVVVSGGHDCVVRAWDVVVDAKGDSAKHVGSSRVFVGHEGTITSVAASPDGVCFASGSYDKTARVWARTRSVFEALGIPDPNDAKKKPAEEEEEEEEELPAGVVVLRGHTDAVTAVAWESVDVVWTGSMDHSLKSFDADAGTCVQTYAAPKCVMGLAVRAGGGMLAWCGGGDRMVHFWDPRVGNATGATTSLASHTEMVVSVAWCPGSEYQLASTAYDGNVKLWDIRGKLPLHTVKAHPGKPHTARALCVDYHGPNRVVSGGIDGRLRIFKVDNEDRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N501</accession>
    <name>C1N501_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52741</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063084.1">
        <property type="nucleotide sequence ID" value="XM_003063038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N501"/>
    <dbReference type="GeneID" id="9688323"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52741"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="34436" checksum="BB6910273B34BFAF" modified="2009-05-26" version="1">MWKSPAVSGSIKRICAAAPAWKFSESREVLSAYEMGAPLAPFAFARVPAAATRSAWPEPAPRRPPAARASGAFARASAPRAGLASARPGGERAAKPPRSGAARGAPLTSFPFVRVTAATRAVGAEPVPWRRPAARASVAADRAFASRPGITSTRPAGERAAEPSRRGTPLAPFAFARVSARGDATRGRAATLGPPGASVAGVARARRRAERRGAVAVTVAPCFSQPSRRSSTRSGRRIRPLTIVHPSSFSYGDAWFGAARVTRVDSSAGVAGTRDTTGDDGVSNASTAKGEAGGASSSSSSSSSLTTAIDWRIGYTVALRVHWFPYSTTALAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5H2</accession>
    <name>C1N5H2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_48771</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063362.1">
        <property type="nucleotide sequence ID" value="XM_003063316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5H2"/>
    <dbReference type="STRING" id="564608.C1N5H2"/>
    <dbReference type="GeneID" id="9688801"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48771"/>
    <dbReference type="eggNOG" id="KOG1989">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967:SF57">
        <property type="entry name" value="AUXILIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="44"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="359"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="544"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="481"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH52498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="575" mass="58686" checksum="863114B6491D6211" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5W2</accession>
    <name>C1N5W2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_53064</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063435.1">
        <property type="nucleotide sequence ID" value="XM_003063389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5W2"/>
    <dbReference type="STRING" id="564608.C1N5W2"/>
    <dbReference type="GeneID" id="9688665"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53064"/>
    <dbReference type="eggNOG" id="KOG2154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ATMECAR"/>
    <dbReference type="OrthoDB" id="10263185at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027193">
        <property type="entry name" value="Noc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455:SF0">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="417"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="635" mass="68424" checksum="A5A603328A3C34FC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N663</accession>
    <name>C1N663_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48852</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063480.1">
        <property type="nucleotide sequence ID" value="XM_003063434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N663"/>
    <dbReference type="GeneID" id="9688919"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48852"/>
    <dbReference type="eggNOG" id="ENOG502R8HT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CATTHAR"/>
    <dbReference type="OrthoDB" id="43442at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007454">
        <property type="entry name" value="UPF0250_YbeD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027471">
        <property type="entry name" value="YbeD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04359">
        <property type="entry name" value="DUF493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117991">
        <property type="entry name" value="YbeD/HP0495-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="207" mass="22508" checksum="AE9B3EE79E3CE9BC" modified="2009-05-26" version="1">MAAALLASVSCRARAPATAASRSIRRRVDRRGRERAGTTARRAAGDDDDDIDARIPDDIPDALKDLVLNDDGDLVDTKTGQVLNDLGATRFDVAVRAMRGEYDPPGASTEKDGGQIFDTLTQFPTSYTFQYSGKASSLSEEDIDDIVKNIIGKTCECEVGDDAVEVKNRGSSRKFVSVWVTCVVHSAEMVTEVLTKLGEDDRVMFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N682</accession>
    <name>C1N682_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitochondrial carrier family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_4326</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063489.1">
        <property type="nucleotide sequence ID" value="XM_003063443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N682"/>
    <dbReference type="STRING" id="564608.C1N682"/>
    <dbReference type="GeneID" id="9688731"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4326"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QSFMCVG"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="100"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="188"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="282" mass="29809" checksum="027C1F6FD17F76CD" modified="2009-05-26" version="1" fragment="single">ALFLAGGCAGALAKTCTAPLDRLKIIMQVSGANQQSAAAKAAASGGLIPAFIAIGKSEGLKGYWKGNVPQVIRILPYSTAMLNSYEFYKSKLADQETGKLSVPARLASGAAAACTATLVTYPLDIIRLRLSVDPNMKTMSQVVTAILKDEGPSAFFKGLPATCLSIAPYSALNFCAFDLFKRAMPDSDSARTIAAASFMATLLASGTCYPLDTIRRQMQLKSSTYTGVVDAGVAIVARDGVGGLFKGFVPNAVKNAPNKSIQLTCFDLFKRKIKESERALEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6M4</accession>
    <name>C1N6M4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_65714</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063577.1">
        <property type="nucleotide sequence ID" value="XM_003063531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6M4"/>
    <dbReference type="STRING" id="564608.C1N6M4"/>
    <dbReference type="GeneID" id="9689200"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65714"/>
    <dbReference type="eggNOG" id="ENOG502S1ZG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DGSITHW"/>
    <dbReference type="OrthoDB" id="529961at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47822">
        <property type="entry name" value="CARBOHYDRATE BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47822:SF2">
        <property type="entry name" value="F-BOX AND WD-40 DOMAIN PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="284"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="504" mass="52267" checksum="BFC16B8B43A5E2C3" modified="2009-05-26" version="1">MPIGAPAPSDSDDDDALSEYEGDENIGYDPSFEGRGGVTASDRDAMVPCNAAKDFREASRYDVADASVAAARDFPDAVLRIASPAGVRAQVSRFNRDGSIVVVGGDDGAARAYHARTGAAFHQFVPSRHGGDGVDAENPGVVTSLRFLPSRGGGGDGGGGGGGGGGDGDNVALVASSSGRLWHWHCTSGKTIGAPVVEPGNQILACDVRGDGETFATAGYDGTIRVYDEATRKLRASLRGWSAGEDPATGAPTRPPWKPAGPPKMVHVGNGEYREKSIVNPVKDCGHADRVLGLAYASDSHDVLVSGGWDNTLQMWDARAGPTSVRRVRGPHVCGDSIHVTPLNDDGARAQVLCGSWRTRRPLQAFDLGTFMFMYEVPFGVVPDAKGEENANANATPCSVYAARFGKDGGPCEGLIFAGGSGGNEVRVISRPGYGDHSGGKAFAPVSAPDGLRTKARLHGLSSPVHGIDLSAGEDRIAVTCADEVLVYDTASLGGLRGRASSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6P7</accession>
    <name>C1N6P7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_53387</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063588.1">
        <property type="nucleotide sequence ID" value="XM_003063542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6P7"/>
    <dbReference type="STRING" id="564608.C1N6P7"/>
    <dbReference type="GeneID" id="9689212"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53387"/>
    <dbReference type="eggNOG" id="KOG2255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FGTCRFK"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1470:FF:000001">
        <property type="entry name" value="Peptidyl-tRNA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="entry name" value="Peptidyl-tRNA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224:SF1">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="Peptidyl-tRNA hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="257" mass="27311" checksum="CD029CDF6431895A" modified="2009-05-26" version="1">MGLPPLLGAPLRLARRVIGFPMRLVNRARGIGGGAADPNRWLVVGLGNPGSKFTRTRHNAGFDAVSLLASAHGMSFTGALKHRSMIATGKIANVPVVLAMPQTFMNLSGEAIRDVLRWYKISPKRMLVLYDDMDSPVGVVKLKGKGGHGGHNGVRNIIDEVTRGEKTFARVKIGIGRPAAGVSVIDHVLRRFTAEEREALERGEVMREAGDAVVAVLTDGLEKAMTRVNNKKPAAKVGGEVGGEDREKAAVAAAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6V6</accession>
    <name>C1N6V6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_5975</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063620.1">
        <property type="nucleotide sequence ID" value="XM_003063574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6V6"/>
    <dbReference type="STRING" id="564608.C1N6V6"/>
    <dbReference type="GeneID" id="9689239"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5975"/>
    <dbReference type="eggNOG" id="KOG1944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IICHYWY"/>
    <dbReference type="OrthoDB" id="10267969at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF17">
        <property type="entry name" value="PROTEIN MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="181" mass="19481" checksum="744EDDB5A8B776AD" modified="2009-05-26" version="1" fragment="single">SFLTAYDAALASAPVLTKSITSWAGFTIADVVAQALTNALDLDANANDDGRSGSGSVRFDPSRTLRNGLFGLAFYGPVSGAWYACLDANVMTEDPNGATAVAAKTFLDQALWAPALVTSLFAWDLACSGEPLRDLIDTLYVNWSFWPAFHVLNFSFVPPGERILYVNVVQVIYNVFLCVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1N789</accession>
    <name>C1N789_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RuvB-like helicase</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_44976</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RuvB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063695.1">
        <property type="nucleotide sequence ID" value="XM_003063649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N789"/>
    <dbReference type="STRING" id="564608.C1N789"/>
    <dbReference type="GeneID" id="9689297"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44976"/>
    <dbReference type="eggNOG" id="KOG2680">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IINTEPY"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002221">
        <property type="entry name" value="RuvB-like 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000002">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="69"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH52068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="466" mass="51468" checksum="034EB86847D8A6EF" modified="2009-05-26" version="1">MAEGGEGVKVAEVKDLTRIERIGAHSHIRGLGLDDALEARKVSQGMVGQVNARKAAGVILSMIREGAIAGRAVLLAGQPGTGKTAIAMGMAKALGEETPFAMMAGSEIFSMEMSKTEALTQAFRKAIGVRIKEETEIIEGEVVEIEIDRPVTSGAAPKMGKLTLKTTEMETVYDLGQKMIESLNKEKVSAGDVVTIDKASGRITKLGRSFARSRDYDAMGAQTKFVQCPEGELQKRKEVVHVVTLHEIDVINSRTQGFLALFAGDTGEIRPEVREQIDAKVAEWREEGKAEIVPGVLFIDEVHMLDIECFSFLNRALENDMAPVLVVATNRGITKIRGTNYKSPHGIPIDLLDRLLIVTTVPYTERELRLILDIRCEEEDVEMTEDAKDLLCKIGHETSLRYSIHLITAAALVAHKRKSAEVEVEDISRVYALFLDVQRSTQFMVEYQEQFMFNEVPEECGDEMDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7B0</accession>
    <name>C1N7B0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Histidyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_36675</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="2"/>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063705.1">
        <property type="nucleotide sequence ID" value="XM_003063659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7B0"/>
    <dbReference type="STRING" id="564608.C1N7B0"/>
    <dbReference type="GeneID" id="9689308"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36675"/>
    <dbReference type="eggNOG" id="KOG1936">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CGGGNFK"/>
    <dbReference type="OrthoDB" id="1906957at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000054">
        <property type="entry name" value="Histidine--tRNA ligase chloroplastic/mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000017">
        <property type="entry name" value="Histidine--tRNA ligase chloroplastic/mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707:SF1">
        <property type="entry name" value="HISTIDINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="88"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="13"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="158"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="350"/>
            <end position="351"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001549-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH52078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="503" mass="55124" checksum="B83FCBEB6F86BF7F" modified="2009-05-26" version="1">MLRAPTTLRSLLSARRAASAARVAPSSPSSPSSSPSLARRRLFSTSQIRAGPAAASAGGGRSTTTTSPDRASSDGARKKMIDLQPPKGTRDFAPEEMRVRNWLFGHFRDVARTFGFEEWDAPVLETEELYVRKAGEEITTQLYNFEDKGNRRVALRPELTPSFARLILQQGKSLALPAKWFAIGQCWRYERMTRGRRREHYQWNMDIVGVDGVEAEAELLAAIVEFFTRLGITSADVGLKVSSRKVLQAVLTRYDVPEASFAPVCVVVDKIEKLPREKIVEELAGLGVTEDAIDGILAAMEMKTIDDLAALLGADADAVKDLTTLFSHAEAYGYADWLVFDASVVRGLSYYTGVVFEGFDRAGELRAICGGGRYDKLLGALGGEDRSMVGFGFGDAVIMELVNDRGLLPESLKTGCVDDLVYPMTAALRPAAMAIAARLRKAGRRVDLVIEDGKKPKWVFKHAERSGAARVVLLGEKEWAEGKVRVKDLASREETDVDPESLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7M6</accession>
    <name>C1N7M6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_53758</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063930.1">
        <property type="nucleotide sequence ID" value="XM_003063884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7M6"/>
    <dbReference type="STRING" id="564608.C1N7M6"/>
    <dbReference type="GeneID" id="9689565"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53758"/>
    <dbReference type="eggNOG" id="ENOG502QVM8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MALNRWN"/>
    <dbReference type="OrthoDB" id="3700at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056309">
        <property type="entry name" value="CGL160/ATPI_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24763">
        <property type="entry name" value="CGL160_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="CGL160/ATPI" evidence="6">
        <location>
            <begin position="306"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="436" mass="46953" checksum="070D9BD9E58D6D92" modified="2009-05-26" version="1">MPATLALPALASRATARGAPRRRAATTRASRRGASERVVAAAAAGASDDDSSERTNAKANAKAKAGAPPKAVNVWERRNVRMWDVDLEAEFERQDKAKRDAAKREEIKAATGLGFASRNMLDDPTVDLSARLRPKKNKKSDGDGDGDGDGGAKKPAYVRVVGGVGPDAPPKLLKGDVDDPGSASSLSAIDLATTKKEKSKYDLDGWNYAPTKARSSSAEQKRWQREWEKGEAIQAKKNPVYAKSKFSTAQMRKLRPKDLKPVVPGRELTEAEKAERRRAADDSYERVKQARSHSHWSPYDPVRVVNANLLLTTAGLCGSGTVAAFFVGGVPLGSSFAFGSAGALFYVKLLASKAEAGGGGQGGPPSILVPVILFMALNRWNTFFAEDVGLALSPIPMLLGFFTYKPASVFQAFRDVMEEEQKDGEGEDEWVVDESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7T0</accession>
    <name>C1N7T0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_53815</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064145.1">
        <property type="nucleotide sequence ID" value="XM_003064099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7T0"/>
    <dbReference type="STRING" id="564608.C1N7T0"/>
    <dbReference type="GeneID" id="9689404"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53815"/>
    <dbReference type="eggNOG" id="KOG2130">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="APSHSHW"/>
    <dbReference type="OrthoDB" id="424465at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF21">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="272"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="494" mass="54845" checksum="9B67F1EF9F8556DF" modified="2009-05-26" version="1">MRPHPLGVLPEGNRYLVSSSDASRSDDARRRGLGALATLPDALVLRCLGGDCDDGESHGVGGEALAAFARCSRACRAFAAHEDLWKQCVLRKHGGDFAFAGRSWRETYAAAAGGVVVESSRDDDDDDDDDDAAAASDAEVARAAPSSARADRPPLFSDALYFRHVSARFPIDERWISRDTIPRRARGALSPEAFARDFEARNAPVIIAGLCADWPAVRDARWSREAMSSDKRWADAKFTVGGYEMRLRDFWRYVDGSRDDLPMYLFDKRFAEKAPGLAKDYAPPPHFSDDLFALLGEDGRPDYRWLIAGGARSGSGFHVDPNGTSAWNAVVSGRKKWIMFNPDVLPPGVHPSEDGTTVTQPVTIIEWYMNFYDHVYEDEGDGESEDSDDDSDDDDDDDQKETAKKRRKVSSPPSSRKNSYHGKVFEGICDPGDVLFVPSGWWHCALNLEETVAVTQNFCSPRTLPRVLRFLDRAKARPVHWSPYDRVRVAHAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8E4</accession>
    <name>C1N8E4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_36911</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064252.1">
        <property type="nucleotide sequence ID" value="XM_003064206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8E4"/>
    <dbReference type="STRING" id="564608.C1N8E4"/>
    <dbReference type="GeneID" id="9689511"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36911"/>
    <dbReference type="eggNOG" id="KOG0480">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NIDTESH"/>
    <dbReference type="OrthoDB" id="496750at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF48">
        <property type="entry name" value="DNA HELICASE MCM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="336" mass="36482" checksum="97FF1255CA2C2A16" modified="2009-05-26" version="1" fragment="single">MASRPPFFVDATVRGATVAAASTRVSPCSIARTSVAASQLLRYIAQAAPRAIITSGMSSTAAGLTVSIANADSRANCSIEAGALALADGGLCCIDEFGFIRPGELTAIHEAMEQQTLSFAKGRVVATLQTRCAVVGACNTKGFAHSLSASLVTSTSFSQPLLSRFDCVMILSDDRNEDADRLLSTHMISLHSTGTSNEQIGKRNLQTETVLKTAKLKLDLFTAEPSSSEHESIRHDFEDIKDDTEARSTRPKLWPLDRIRSYIALVRSNIDPAISTEAEALLRGYYQMQRRKKENISGHPTIRLLESLIRLTQAHARLLWMDMATERDVVVAVSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8N0</accession>
    <name>C1N8N0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic</fullName>
            <shortName evidence="6">RA</shortName>
            <shortName evidence="6">RuBisCO activase</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_23296</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Plastid</location>
            <location evidence="1 6">Chloroplast stroma</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RuBisCO activase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064296.1">
        <property type="nucleotide sequence ID" value="XM_003064250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8N0"/>
    <dbReference type="STRING" id="564608.C1N8N0"/>
    <dbReference type="GeneID" id="9689553"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23296"/>
    <dbReference type="eggNOG" id="KOG0651">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2014558at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046863">
        <property type="term" value="F:ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044960">
        <property type="entry name" value="RCA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048571">
        <property type="entry name" value="RuBisCO_activase_AAA_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32429">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32429:SF11">
        <property type="entry name" value="RIBULOSE BISPHOSPHATE CARBOXYLASE_OXYGENASE ACTIVASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21228">
        <property type="entry name" value="RuBisCO_activase_AAA_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="8">
        <location>
            <begin position="212"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Ribulose bisphosphate carboxylase/oxygenase activase AAA helical" evidence="9">
        <location>
            <begin position="364"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH51918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="505" mass="57055" checksum="F6189743EEBC1E9C" modified="2009-05-26" version="1" fragment="single">MRAAAPSATATPRIATASRRDATRRDGFRPSRARHRRWTTRNNDDVRRRAARGHHDDRDLDFDPYADDGRAGPPPSRAAASHGRHQSSWTATETSQDVKGVDYLVELGKQSSNTNTEVGARKGIIDDVFAGTANAKFNLGADSDIASGRLRYRDVEHVRSFKNLFGDFHVPPLFVDKVSLHVAKNLMADSDNPGASANPLGGLTKVPLILGVWGAKGCGKTFNLELACKALDITPVVMSAGELEDEWAGNPGRLIRSRYRKAAEIIRNHGKMSCLIINDIDAGVGRFKRTQATVNTQMVMGTLMNLCDHPTQVSNEEDDEIHEYREEERIRRVPIIVTGNDLSTLYAPLLRDGRMEKFYWQPTRTDIADMVHAMYRDDDVSRETVERLVARHEGQPLDFFGATRARMYDRCIVEWAESFRSETPDPVTGQRHVTKAMGEHLMKNRTRERPDDEHDPGDFVLWKPDFTVQDCSEEALMRHADDLAREQRLVNEKRLSEDYMRTMKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8Q7</accession>
    <name>C1N8Q7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54206</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064317.1">
        <property type="nucleotide sequence ID" value="XM_003064271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8Q7"/>
    <dbReference type="STRING" id="564608.C1N8Q7"/>
    <dbReference type="GeneID" id="9689930"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54206"/>
    <dbReference type="eggNOG" id="KOG1109">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HIAFFTM"/>
    <dbReference type="OrthoDB" id="2016540at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="394" mass="43671" checksum="7387384C236CBD4B" modified="2009-05-26" version="1">MERDLARDRQKITFARRPIRVLALFARVCVDGVRGALRWLHRHRFLALYPLLLLVVLVSLAASITGPHTPFITDARITTEFVVWWLGLGVLSSIGLGTGMHSGLLFLFPHILKVCRSAEACDGVGFDTRNNMWFTMGGEDLFECDNVSKDDTWMNVWLAVLPAAVTWGAGTAIGEIPPYWISYLAATAGKENDDLYDLENEDVGEMTRMQRKIHDCKVWMISFMKTHGFWGLVAMSSWPNAAFDLCGICCGTFMMPFWSFLGAVLIGKGLVKAPMQAAVMSTVFSTGPRTYIIGTIASAFPPGWGVRDFLNDGAAKAIGKMNGKKKTAAAKGGLSLSTMWGYLITIFVAYFATSCIEQMAQMKQANIDKKEVERKLGHRRSVRRSLGSTPKKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9N5</accession>
    <name>C1N9N5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54556</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH50978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064644.1">
        <property type="nucleotide sequence ID" value="XM_003064598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9N5"/>
    <dbReference type="GeneID" id="9690208"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54556"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH50978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="209" mass="22937" checksum="52D363B6A280C87D" modified="2009-05-26" version="1">MHAARAPVLRPLGAAPARKRHAARASRTLRGRALVAASSENEETTTIITNNDHRPTASVEETASGDLLYRFADVDSRTGALAFTSRDGVDVYALGAMARIAEETNPVGPSEDAALRLATKMRTDLNDDDDDDVEAAGARLVASLRAELDDARAKLKRAEEDERYARDELEVARVALVEEARERVSATRELKATHDLQVWDLEDYIQVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9P9</accession>
    <name>C1N9P9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43593</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064772.1">
        <property type="nucleotide sequence ID" value="XM_003064726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9P9"/>
    <dbReference type="GeneID" id="9690094"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43593"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="222"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="63"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="314"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="391" mass="41271" checksum="A22A7F6AC2F0454C" modified="2009-05-26" version="1">MEREEHEHVLGEFEKANETLGRATGKLADVLSHARRDVEGLFGKLERKAGLERTNEEAIAAIKESVAARLIEMEERLSEAAERERERRRTHVAAMKAFAKRKDEETAALRKKLDAMAAEINATRASLDARRDADVAEIDAMAEALAASPENEAVMTRSAADAGELAATLSSAFAKLARDVPTGGTPARETVAAALTTPVEAKTMARMTLRREATLAAFRATKAAGGGGGEKAAGAHPYDEDDDEEEGGGEDAAGESAVDVLDVTAEAEEEDVTPPAPTTTEEEEEEEEEEEEKTQKPAMCASTRRGGGTRGRSTRGAAKKTAAAADAEDAAADDGGDAAVDVSSSPAPTKTKTSAGSRGRAPTTTKIPTQAKNRAPLEPLERENSVEPPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA23</accession>
    <name>C1NA23_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_43677</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064714.1">
        <property type="nucleotide sequence ID" value="XM_003064668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA23"/>
    <dbReference type="GeneID" id="9690155"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43677"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="102" mass="9915" checksum="0142AD50B80BF410" modified="2009-05-26" version="1">MSQTGPLSHAGSFDCAGMISVSAAIASATSAGSSSGDFSSLQSRNFLSSPRRPSLPPGSAMISPIASNAALTASAHASDPPTTDARSASPTTASYPGIASDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAE6</accession>
    <name>C1NAE6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54869</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064891.1">
        <property type="nucleotide sequence ID" value="XM_003064845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAE6"/>
    <dbReference type="GeneID" id="9690331"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54869"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="121" mass="13284" checksum="105ED8D0BF097044" modified="2009-05-26" version="1">MSPSVSSNTSTPSNSVCLSICSASWSSSSSKAATISSSSLARNSMSFLSASSVSSYRRERRRNRIPLRPRYPKTFPARWPRADPGGSNQNRWGEPIFHPILQLNPSMDRICVVCSSVLCSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAF1</accession>
    <name>C1NAF1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54875</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064894.1">
        <property type="nucleotide sequence ID" value="XM_003064848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAF1"/>
    <dbReference type="STRING" id="564608.C1NAF1"/>
    <dbReference type="GeneID" id="9690394"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54875"/>
    <dbReference type="OrthoDB" id="567606at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="359" mass="41429" checksum="ACED5EE20F28378B" modified="2009-05-26" version="1">MARNASARSWRAWRKGSGRLSFSRMMTRLKFLGMFCLMLMGLHYLTLLYLNQGLRIIHNDSFTHVLHLNIRDKQISDTNGINHTPTYWTPFHRYMEKIKHCKKCPRVHKWEPYFAAYTEQLSRFRGRKVVMMEVGVQSGGSMMMWRSFFGCRFEYYGIDINPQAQQFASEWATIFIGDQGNPEFWKDIKKKVPVIDIFLDDGGHNMSQQFTTFEAMFPHVKSRGGVYVCEDLSTSYSANFLGQPLSNGTVQEYGRTGGKTFVELSKKMIDWLNCYFVSGDVMAASASCPPIFDGLPAVSEFKQFGYSLHFYSQIIFIQKERVIPPFHYMAGGYSFPYGYSTTVWDGNRYDAPAEAIIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAG8</accession>
    <name>C1NAG8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_49346</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064906.1">
        <property type="nucleotide sequence ID" value="XM_003064860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAG8"/>
    <dbReference type="STRING" id="564608.C1NAG8"/>
    <dbReference type="GeneID" id="9690399"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49346"/>
    <dbReference type="OrthoDB" id="6350956at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029526">
        <property type="entry name" value="PGBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599:SF3">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13843">
        <property type="entry name" value="DDE_Tnp_1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PiggyBac transposable element-derived protein" evidence="2">
        <location>
            <begin position="103"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH50886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="454" mass="49375" checksum="808672BCFA4E7CCD" modified="2009-05-26" version="1">MRELAMAAAETSGGLVGALADDDIGAAGEGDAGEEVMDSDDDDIDIEAALGRGDYAAADPYEDMQEEEEIEAIEDPTSRLLTFRFLGGTRIRLNGHGATFIFDRKAGETVKDIVFDLISALPHHGFHIATDNYFTSPGLFRWINMTFNIKVHGTLRPNYGICPAFRDPAVRDALEALGEGAFEPPQYGDSGLVQWLWMDSSLVNFLSTVPSHHVDSTSTYLDVTRRIPGTGSVTQPAPRVASDYNKLMKVVDKVCTTRARSALFSSLHLLSPRLTPLDPIHLRHQCDQMRGTYSVQRRCKKWTGAIVSWVLDVVAINIYALLRKARGDFVQQGFKVGKLNARDAVQKKLIAGLLARGSSTPPESGEGASAVRKRKRASKGSAGRTPSGGSAAPVAADCVSIPRDVAAHFVMVKGGKGDCAWCKEKLDIRKQTFQRCNHKDCGVSLHTKLGCWGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGL8</accession>
    <name>C1MGL8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_37709</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054797.1">
        <property type="nucleotide sequence ID" value="XM_003054751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGL8"/>
    <dbReference type="GeneID" id="9681045"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37709"/>
    <dbReference type="eggNOG" id="ENOG502SRPG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10522163at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="403" mass="42647" checksum="D9692933B0CB254D" modified="2009-05-26" version="1">MNTVPIPKRKLLLCVRFDLSETESAVGAIDARSGGVVHDECAKAAAGASNLLDPIGVVGSCVATAGELSIEDAQALPFVASATLGCADPAVEFSWAYSSTAPVAVMRVLVSLAKCDGVTALRIGLHAMELLEGGPNDGKISSPGGFAAPPPIRPGLRHALNFANMLRRTLSSIVAASAFKLGDPLGANKLIGAKEGVIVPTTARSTIAYWAQEKPAPTSFALYAAASPKSKKAEGGETVKPYRAFLSAIENWRVKLGLRACFVLVNQRPLVVPTEVRKVTDIADDRDFRVRYAGAFGGPEAPPGDDVWPLNNFYMANVVFVNNYGRHARTFKAKATAFMWDWIGMGAHVWGGGCVEINGRFLAWVRGTREGIDACEDELAGAVGAKKEALTQARWDVIVPGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGP3</accession>
    <name>C1MGP3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Chloride Carrier/Channel family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_49887</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054812.1">
        <property type="nucleotide sequence ID" value="XM_003054766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGP3"/>
    <dbReference type="GeneID" id="9680885"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49887"/>
    <dbReference type="eggNOG" id="KOG0474">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498106at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015108">
        <property type="term" value="F:chloride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051280">
        <property type="entry name" value="Cl-channel/antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689:SF161">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="10" id="KW-0868">Chloride</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="398"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="577"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH60064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="674" mass="69328" checksum="E34C8ABAD97CCB05" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHB8</accession>
    <name>C1MHB8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61282</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054929.1">
        <property type="nucleotide sequence ID" value="XM_003054883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHB8"/>
    <dbReference type="STRING" id="564608.C1MHB8"/>
    <dbReference type="GeneID" id="9681217"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61282"/>
    <dbReference type="OMA" id="MGREPMT"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="866"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="976"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1049" mass="113296" checksum="027694CB587B7C93" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIB2</accession>
    <name>C1MIB2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50505</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055638.1">
        <property type="nucleotide sequence ID" value="XM_003055592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIB2"/>
    <dbReference type="GeneID" id="9680334"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50505"/>
    <dbReference type="OMA" id="NDHEIRG"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="101"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="396"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="501"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="533" mass="56002" checksum="DB146D2319B00A68" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIN4</accession>
    <name>C1MIN4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50633</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VHL family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055697.1">
        <property type="nucleotide sequence ID" value="XM_003055651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIN4"/>
    <dbReference type="GeneID" id="9681204"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50633"/>
    <dbReference type="OrthoDB" id="413400at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05468">
        <property type="entry name" value="pVHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.780">
        <property type="entry name" value="von Hippel-Lindau disease tumour suppressor, beta domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024053">
        <property type="entry name" value="VHL_beta_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037140">
        <property type="entry name" value="VHL_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036208">
        <property type="entry name" value="VHL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022772">
        <property type="entry name" value="VHL_tumour_suppress_b/a_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01847">
        <property type="entry name" value="VHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49468">
        <property type="entry name" value="VHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="von Hippel-Lindau disease tumour suppressor beta" evidence="3">
        <location>
            <begin position="42"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="218"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="329" mass="35897" checksum="507F2FAA8048B326" modified="2009-05-26" version="1">MDDADSDADADAGVADYGVERYDDPERHDPLRDRLLPALGLASRESRHSVIVTFLNACGERCRLYWIDYAGKVVRYKTLSPGETHRQQTFETHPWTFATVPDDDAVASGGGFRRRRLAVNGYPVYFASRERDGDGDGDGETTGAGDSTRRITRPGCKAWRHDAHREFPRFFRDVSRAFLMTHARLRRERAAAAAEGEGGDAGDVVRVSVVNDAAMDVEDAPVSSRTRARTRVSSAPAEAATVSSASGDEDDDEDDDDDDEKRNENENDSAARHTLGSLPSDVVHHIVKLAAPSVPFFLPVDDVRCDVEEAVATSESEEEVANAAADATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIX3</accession>
    <name>C1MIX3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein yippee-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_50730</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the yippee family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055737.1">
        <property type="nucleotide sequence ID" value="XM_003055691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIX3"/>
    <dbReference type="STRING" id="564608.C1MIX3"/>
    <dbReference type="GeneID" id="9680388"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50730"/>
    <dbReference type="eggNOG" id="KOG3399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HAMNIST"/>
    <dbReference type="OrthoDB" id="6407410at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034751">
        <property type="entry name" value="Yippee"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039058">
        <property type="entry name" value="Yippee_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13848">
        <property type="entry name" value="PROTEIN YIPPEE-LIKE CG15309-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51792">
        <property type="entry name" value="YIPPEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Yippee" evidence="5">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU110713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="120" mass="13653" checksum="CF765CFB4B71CF57" modified="2009-05-26" version="1">MPASSSPPILPVPCVRLAGDRIYSCAVCRTHTSFHDDVISKAFQGRHGRAYLFNDVALPNVVLGEKEDRLLMSGLHTVRDLRCVKCQTTLGWKYEIAWERSQKYKEGKFILEKALVVCEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIX5</accession>
    <name>C1MIX5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Auxin efflux carrier family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_50732</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055738.1">
        <property type="nucleotide sequence ID" value="XM_003055692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIX5"/>
    <dbReference type="GeneID" id="9680961"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50732"/>
    <dbReference type="eggNOG" id="KOG0231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WDAPNAV"/>
    <dbReference type="OrthoDB" id="270720at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_transp_PIN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36838">
        <property type="entry name" value="AUXIN EFFLUX CARRIER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36838:SF3">
        <property type="entry name" value="TRANSPORTER AUXIN EFFLUX CARRIER EC FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="581"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="596"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="610" mass="62761" checksum="FA13B2FE1B1A5E7F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ03</accession>
    <name>C1MJ03_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50759</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055749.1">
        <property type="nucleotide sequence ID" value="XM_003055703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ03"/>
    <dbReference type="GeneID" id="9681197"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50759"/>
    <dbReference type="eggNOG" id="ENOG502T0D8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="567976at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH61001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="381" mass="40119" checksum="F6FFB277C2EDAA23" modified="2009-05-26" version="1">MPAHTLAELKARGRGGRGAGGRGGRGRGRGGGGGGGRGRGRGRGRGGADDAGFAAFNGDARKLAPSPERNPWTHAAGLAAERTIASPRTVAASWARKQEEIEDVGALMRYEAERANERRADEREKTKAAAREAGADVIDLLSDGDDNGADVAKEKRRREKRKSAEGEEEEEEEMKKKKKAARPPWKENGGRAAEELAAARRRAAIEASKRAATRGGRSGGVGHGHGDVAAGSSGGNPLWNPARYVPPPPGAGGVSASDLTLSTDEVAEVRDVNGNWYPCNACLDTGNGGCTLIVRRTAIRMGLCDGYGNPLAGGRMRYVHVRGVVEGASEKVPTTTIEYRIKGKTMIVDAGITGAEMGCDLLVSRAEIARFEDDGFTLRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJH0</accession>
    <name>C1MJH0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_14447</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056618.1">
        <property type="nucleotide sequence ID" value="XM_003056572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJH0"/>
    <dbReference type="ESTHER" id="micpc-c1mjh0">
        <property type="family name" value="DPP4N_Peptidase_S9"/>
    </dbReference>
    <dbReference type="MEROPS" id="S09.A03"/>
    <dbReference type="GeneID" id="9681616"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14447"/>
    <dbReference type="eggNOG" id="KOG2281">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VTHMTPQ"/>
    <dbReference type="OrthoDB" id="16520at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.140.10.30">
        <property type="entry name" value="Dipeptidylpeptidase IV, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050278">
        <property type="entry name" value="Serine_Prot_S9B/DPPIV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731:SF193">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731">
        <property type="entry name" value="PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dipeptidylpeptidase IV N-terminal" evidence="3">
        <location>
            <begin position="141"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="2">
        <location>
            <begin position="594"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="825" mass="90091" checksum="5A1C26AE410BCC12" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJU0</accession>
    <name>C1MJU0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_46491</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ADIP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056272.1">
        <property type="nucleotide sequence ID" value="XM_003056226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJU0"/>
    <dbReference type="STRING" id="564608.C1MJU0"/>
    <dbReference type="GeneID" id="9681643"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46491"/>
    <dbReference type="OrthoDB" id="312015at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021622">
        <property type="entry name" value="Afadin/alpha-actinin-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47057">
        <property type="entry name" value="AFADIN/ALPHA-ACTININ-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47057:SF1">
        <property type="entry name" value="AFADIN_ALPHA-ACTININ-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11559">
        <property type="entry name" value="ADIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="314"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="487"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="560"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="616"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="164"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="335"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="430"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="508"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="562"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="618"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="640"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="650" mass="70281" checksum="25BF052662BCFC5F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML15</accession>
    <name>C1ML15_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">TUB1</name>
        <name evidence="16" type="ORF">MICPUCDRAFT_70188</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056479.1">
        <property type="nucleotide sequence ID" value="XM_003056433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML15"/>
    <dbReference type="STRING" id="564608.C1ML15"/>
    <dbReference type="GeneID" id="9681388"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70188"/>
    <dbReference type="eggNOG" id="KOG1375">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PSAMMEN"/>
    <dbReference type="OrthoDB" id="563915at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000006">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000005">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="14">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="15">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="419"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="429"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH59855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="443" mass="49615" checksum="C3D2A0FBD84271EA" modified="2009-05-26" version="1">MREIVHIQGGQCGNQIGAKFWEVICDEHGIDPTGTYCGDSDLQLERINVYYNEASGGRYVPRAVLMDLEPGTMDSVRSGPFGQIFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVLDVVRKESESCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVVPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPTFGDLNHLISAVMSGVTCCLRFPGQLNADLRKLAVNLIPFPRLHFFMVGFTPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASALFRGRMSTKEVDEQLLNVQNKNSSYFVEWIPNNVKSSVCDIPPKGLKMAATFIGNTTAVQEMFKRVSEQFTSMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDASAEEEGEFDEEEEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM70</accession>
    <name>C1MM70_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_3567</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057348.1">
        <property type="nucleotide sequence ID" value="XM_003057302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM70"/>
    <dbReference type="STRING" id="564608.C1MM70"/>
    <dbReference type="GeneID" id="9682322"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3567"/>
    <dbReference type="eggNOG" id="KOG1378">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ATHASWE"/>
    <dbReference type="OrthoDB" id="407721at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PAPs-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="ACID PHOSPHATASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953:SF153">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="3"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="4">
        <location>
            <begin position="211"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="264" mass="29116" checksum="25A3E26875814475" modified="2009-05-26" version="1" fragment="single">VVFGVVGDTGQTEVTRGVLKHLSEMKPHALLHTGDLSYADGFPPRWDTFGRLAEPLMSKVPMLVVAGNHDVTLNGVESTAFRARYPTPYLASGSASQDWFSHDVGIAHVIGLNSYAPVTPGRFDGSNAPMFEWLKGDLASIDRALTPWVIVMFHVPWYSSNAGHYKEALRAQEKLEPLLYDAGVDVVLNGHVHAYERSRPVRDWKEDACGAVHLTVGDGGNYEGPYGQSWSEPQPAWSAFREGSFGAGRLEILNATHASWEWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMP2</accession>
    <name>C1MMP2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56604</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057439.1">
        <property type="nucleotide sequence ID" value="XM_003057393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMP2"/>
    <dbReference type="GeneID" id="9682403"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56604"/>
    <dbReference type="OMA" id="ACLERTH"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="618"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="695"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="802"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="831"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="910"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="975"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="280"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="378"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="705"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="806"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="841"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="939"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="980"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1029"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1066"/>
            <end position="1076"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1116" mass="118154" checksum="9FE79656B6A50AF7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN59</accession>
    <name>C1MN59_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56791</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057523.1">
        <property type="nucleotide sequence ID" value="XM_003057477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN59"/>
    <dbReference type="STRING" id="564608.C1MN59"/>
    <dbReference type="GeneID" id="9682486"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56791"/>
    <dbReference type="eggNOG" id="KOG4549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GVWAWRK"/>
    <dbReference type="OrthoDB" id="2865258at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010033">
        <property type="entry name" value="HAD_SF_ppase_IIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01681">
        <property type="entry name" value="HAD-SF-IIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01685">
        <property type="entry name" value="MDP-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01131">
        <property type="entry name" value="C1.5.2:_MDP_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="281" mass="30437" checksum="1E7F01D00962CA07" modified="2009-05-26" version="1">MASATIATLATLAPVARRGGGGRGDRGSGGRRGGGRGRGGVMSSGGAERQKTRTRHPRRRPHRAANDETMDAPATLWAPPLDGQDLPALVCFDLDDTIWFPELYMMRGAPWTKERCDTTGRERVMDASGEELRCYPAATAAMAMLRSHAAFAKRGTKIAVASRTNRGAWADEVMGMFVVDDGSGSGTTTTMRECVGDLVEMYSGTKKRHFEKLKARTGIPYADMLFFDNEEQNTRDVATLGVTCVLCVGGMTERAWEDGLRAFAEKKALVARRRAAAAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN82</accession>
    <name>C1MN82_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_62698</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057059.1">
        <property type="nucleotide sequence ID" value="XM_003057013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN82"/>
    <dbReference type="STRING" id="564608.C1MN82"/>
    <dbReference type="GeneID" id="9682498"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62698"/>
    <dbReference type="eggNOG" id="KOG0120">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="431068at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12254">
        <property type="entry name" value="RRM_hnRNPH_ESRPs_RBM12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="174"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="386" mass="40476" checksum="A5A571F0F88CE2AA" modified="2009-05-26" version="1">MLSEVFNNALASLSPEGPAVLGVNMSPDNKFAFVELRTIALSDAAQHLDGIELCGRNMKVGRPKGWVDPSAEAKATAAAAEAPTVASGVKATTSAAAAAAAAPAADTVGQGLFPTPNDDADDPAMQNARATMHMRATSERDATMAIAEVNTRFPPTPLGVPAQTLTRRCVLLDGMVSSGELSSPRSREEFKEDLREECAKCGIIDAMVVPPPPREAIDAGDPGRAYVSFQAECSARAAKDMLNGRVFDGRVVAASLASDAEFERARNGEWLPPRPPPGDPSLCGILRVRGMPPEATKADVVNFFYGMGAEEDKVKIIIAPGMANLAGSHPGAMSTGEAFVEFSGDDANIQQAALKDRAVLGGKPVSVFRSSLEEVQRVALMGRTMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNM9</accession>
    <name>C1MNM9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Multidrug/Oligosaccharidyl-lipid/Polysaccharide flippase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_55963</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056675.1">
        <property type="nucleotide sequence ID" value="XM_003056629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNM9"/>
    <dbReference type="STRING" id="564608.C1MNM9"/>
    <dbReference type="GeneID" id="9682576"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55963"/>
    <dbReference type="eggNOG" id="ENOG502T1ZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NSCIEPV"/>
    <dbReference type="OrthoDB" id="498763at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF44">
        <property type="entry name" value="PROTEIN DETOXIFICATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="522"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="558"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="597"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="19"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="128"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="740" mass="76109" checksum="B7C754C317EFC9AB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNN8</accession>
    <name>C1MNN8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_8851</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057141.1">
        <property type="nucleotide sequence ID" value="XM_003057095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNN8"/>
    <dbReference type="STRING" id="564608.C1MNN8"/>
    <dbReference type="GeneID" id="9682130"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8851"/>
    <dbReference type="eggNOG" id="KOG0716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HWVPFES"/>
    <dbReference type="OrthoDB" id="566614at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45295">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ C76, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45295:SF1">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ C76, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13370">
        <property type="entry name" value="Fer4_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
        <property type="entry name" value="3FE4SFRDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="83" mass="9660" checksum="764296ACBBF92DEE" modified="2009-05-26" version="1" fragment="single">RAVFVNESACIGCRQCNHSAPKTFMMEDDWGRARAYQQWADTEEDITIAIESCPVDCIYWVKQRNLPILEYAMQRCERQNVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP13</accession>
    <name>C1MP13_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56105</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056741.1">
        <property type="nucleotide sequence ID" value="XM_003056695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP13"/>
    <dbReference type="GeneID" id="9682180"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56105"/>
    <dbReference type="OMA" id="SWARFAI"/>
    <dbReference type="OrthoDB" id="2020822at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912015" evidence="2">
        <location>
            <begin position="21"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="102" mass="10845" checksum="550D8E5E21ADEA38" modified="2009-05-26" version="1">MCPMRWVLLLFSGIIAGYLAWTSSWFSASGEDVGEAPRGGDEGARRGRATADGGVASWARFAIDGLSGRYLYMMLHASRKDAAGKGGAEGGRITRSRSKKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP54</accession>
    <name>C1MP54_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_46658</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057225.1">
        <property type="nucleotide sequence ID" value="XM_003057179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP54"/>
    <dbReference type="STRING" id="564608.C1MP54"/>
    <dbReference type="GeneID" id="9682664"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46658"/>
    <dbReference type="eggNOG" id="KOG2935">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DQHWFAV"/>
    <dbReference type="OrthoDB" id="498556at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033865">
        <property type="entry name" value="Ataxin-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006155">
        <property type="entry name" value="Josephin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14159">
        <property type="entry name" value="ATAXIN-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14159:SF0">
        <property type="entry name" value="ATAXIN-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02099">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01233">
        <property type="entry name" value="JOSEPHIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01246">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50957">
        <property type="entry name" value="JOSEPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Josephin" evidence="16">
        <location>
            <begin position="2"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="14">
        <location>
            <begin position="362"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="15">
        <location>
            <begin position="367"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="336"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="342"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR633865-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH58870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="442" mass="45480" checksum="0EB50FA2CEFDDFB9" modified="2009-05-26" version="1">MARLLYHEKQTSMLCGVHALNTLLQGPYFSAHDLAAIATEFDERERALMRESGVESADFLRYMAEDSGNAAADGNFSIQVLTKALEVWNLTCVPATSREAGSAWRSPQDEVAFLCNLDQHWFAVRRRDDVESPSVHAGGGFGGKKGSAPKPGGWWNFNSMFPAPQPISELYLSAFLAQLKEEGYSIFVVRGALPAAADASSSGTYGRWVNVEDAAADNKAADAVKAAGRARCAAEQAMARVGAGGRATLTTLARGGGGGGGGGEGSADDAELQAAIAASLGHGHGHGHGGGAGKRDSAEDAARALAASFAGAGAPSAGGGDDADADLAAAIAASLAQSTPPHSQPPPPPMALPPVPDEPAAGDPAAVTLAVRVPSGRRLSRRFRDVDAVAAVAAFVAAETGVDMSRHALVAAFPRRPLSDLGRTLKDAGVKDKEALSVEPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP66</accession>
    <name>C1MP66_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein TIC 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TIC20</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_46663</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in protein precursor import into chloroplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Tic20 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057232.1">
        <property type="nucleotide sequence ID" value="XM_003057186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP66"/>
    <dbReference type="STRING" id="564608.C1MP66"/>
    <dbReference type="GeneID" id="9682206"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46663"/>
    <dbReference type="eggNOG" id="ENOG502QT65">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WMELWIF"/>
    <dbReference type="OrthoDB" id="602284at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005691">
        <property type="entry name" value="Tic20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510:SF9">
        <property type="entry name" value="HIT-TYPE ZINC FINGER FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16166">
        <property type="entry name" value="TIC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1001">Plastid inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="9" id="KW-0946">Virion</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="267" mass="29116" checksum="8944B86BF1563BE9" modified="2009-05-26" version="1">MASTSRAFSLASAVPSRAKSKAAKRCARAGAAPAGKPRGMRGSTTGAPRHAGVETMNDDVGVPSGVSMARKTRRGTVVAQVGDIPPGMPRFQEDPKGFWEIFFGKNPNKGKIHAQLKHRALSLLPYLIPCMGAIAFTGEAFMAYPVCINIALAISPLLQIFYSNSFIPFVTFFTLFLTVVRNTTMPHFVRYNTMQAILLDICVMLAGLIMQYLPMYITTSFIGDILELGTLTNALLAIGYCMWNVIQGIYPEIPIITEAVYAQVRDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQW4</accession>
    <name>C1MQW4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_7600</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0585 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057825.1">
        <property type="nucleotide sequence ID" value="XM_003057779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQW4"/>
    <dbReference type="GeneID" id="9683639"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7600"/>
    <dbReference type="eggNOG" id="ENOG502QVX9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YLYGPYK"/>
    <dbReference type="OrthoDB" id="10258744at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010342">
        <property type="entry name" value="DUF938"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20974">
        <property type="entry name" value="UPF0585 PROTEIN CG18661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20974:SF0">
        <property type="entry name" value="UPF0585 PROTEIN CG18661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06080">
        <property type="entry name" value="DUF938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="192" mass="20651" checksum="830E832F30C3DE3A" modified="2009-05-26" version="1" fragment="single">AAERNKEPIAAVLTRYLGEEKSGVILEVACGTGQHAAHCAPLLPNLWWQPTDLGTDAFDAVDHHTRGIKNVSHALEMDGSNNFMLVKDGTFTAVLAVNLTHISPYAATKGLVAGAGDALRVGGKLFIYGPFKRNGEHTSEGNATFDASLRSQNAEWGYRDIEAVEQLGRDAGLTPTETVEMPANNFMLVMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQZ0</accession>
    <name>C1MQZ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Arsenite-antimonite efflux family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ARSB</name>
        <name evidence="11" type="ORF">MICPUCDRAFT_57463</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CitM (TC 2.A.11) transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058213.1">
        <property type="nucleotide sequence ID" value="XM_003058167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQZ0"/>
    <dbReference type="GeneID" id="9683277"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57463"/>
    <dbReference type="eggNOG" id="KOG2639">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LARCGII"/>
    <dbReference type="OrthoDB" id="442352at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01116">
        <property type="entry name" value="P_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000802">
        <property type="entry name" value="Arsenical_pump_ArsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051475">
        <property type="entry name" value="Diverse_Ion_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43568">
        <property type="entry name" value="P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43568:SF1">
        <property type="entry name" value="P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00758">
        <property type="entry name" value="ARSENICPUMP"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="544"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="580"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="696"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="748"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="774"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="804"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="847"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="888"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="933"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="domain" description="Citrate transporter-like" evidence="10">
        <location>
            <begin position="533"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH58164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="958" mass="104269" checksum="57D642014AA6998C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQZ8</accession>
    <name>C1MQZ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57472</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057841.1">
        <property type="nucleotide sequence ID" value="XM_003057795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQZ8"/>
    <dbReference type="GeneID" id="9683657"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57472"/>
    <dbReference type="OMA" id="EWRASMS"/>
    <dbReference type="OrthoDB" id="10677490at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="250" mass="26058" checksum="A3137864E6572531" modified="2009-05-26" version="1">MSRRESDASASASDTSDDDDDGGILATIKNQIRADEERFKREDEVIRARGGPSPAAAAPVAPRRQMTTAATRHVAPPQRRGGTPISVPGRAPSARANPARAVGTSVAGGVPPRPVAVREPSRATTTTSASGLGPAATALMKELEDVLADDDAFKPRRATTAAAAAKDAAPEPEWRASMSSAAATAREITRGGEELRERVAAARGKVNTLSGSADLLREIEAMTKELGDGVESFGRELREVAKLNDVDLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRB9</accession>
    <name>C1MRB9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_67636</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058278.1">
        <property type="nucleotide sequence ID" value="XM_003058232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRB9"/>
    <dbReference type="GeneID" id="9683716"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67636"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="103"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="352"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="709" mass="78421" checksum="D07DB6C500A8EC9C" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRH3</accession>
    <name>C1MRH3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_47175</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057926.1">
        <property type="nucleotide sequence ID" value="XM_003057880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRH3"/>
    <dbReference type="GeneID" id="9683747"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47175"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="368" mass="37643" checksum="A269A43688FEA0D5" modified="2009-05-26" version="1">MGTEGTDTNRGTVSVDEFVVFLRARNSDPPVAAEPEAFFAPRPSTSFPAPAPASTSLRYPRSIDPTSTTSAGGFAGDDRADTSADAADAAVGVFSPRQPCSHPHPPGAGSAAASCSRAAVAAASRVAAVAAAAVASRFAASGEPSLLTSFAVSSPELPPPPCAAASASASVVDASRSSFAATSRSPSRVFSSPPAVSSPSPRFARALAVSSASFSTSDAMSSGSSESARARRSRSAREMDEIVRRNGCGPASRPSSEFTPELPRDVDATPLRRRAISPSKLLMSSSESSSSVAPSSKMLTSALCAPPSSSDAASRATSTSSAVSVVSTKNASPFRPKRIVKSVRTPFTVTVTTFSGPRMRPWYFPNRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRN9</accession>
    <name>C1MRN9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_39845</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058908.1">
        <property type="nucleotide sequence ID" value="XM_003058862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRN9"/>
    <dbReference type="GeneID" id="9684347"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39845"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="159" mass="17875" checksum="EC03A0C95F62C9B1" modified="2009-05-26" version="1">MASSKPEWLKEASQAETERRLQFYKRQDKPCFFNGQGNPDQAKYREGSNRRMYTREEREDDAKKAFAEGDLEKALTSFVRAAELCILRRASEPDEEDKDGNDDDDAREPAKEREARPLVMFASGLHTLFGNIAAVLTKLGRIMSTLSSSTSTSSLSSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRZ5</accession>
    <name>C1MRZ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cwf15/Cwc15 cell cycle control family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_33637</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC15 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058961.1">
        <property type="nucleotide sequence ID" value="XM_003058915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRZ5"/>
    <dbReference type="STRING" id="564608.C1MRZ5"/>
    <dbReference type="GeneID" id="9684033"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33637"/>
    <dbReference type="eggNOG" id="KOG3228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KYREHGQ"/>
    <dbReference type="OrthoDB" id="30179at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="66"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="229" mass="25443" checksum="1A9A7D629ACF751F" modified="2009-05-26" version="1">MTTAHRPTWAPAKGHEEQGGARMFGPSHKHSKLDDNAHMTLKTRTDGQQSIKELMARDFKAELEEKERKHFKKKLGGGDGGGDGELMLGDGGIEESSAARFAPKAIDADDSDDDDDDGASGSDSDDDEDDTAALLAELDRIKTERAEEAARKEADRLEAEALERAEEVAGGNPLLDLRQGAADFTVKRRWDDDVVFKNQTRGEPKSQKRFINDTIRSDFHKRFLNKYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSB0</accession>
    <name>C1MSB0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">EF hand domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58416</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059020.1">
        <property type="nucleotide sequence ID" value="XM_003058974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSB0"/>
    <dbReference type="STRING" id="564608.C1MSB0"/>
    <dbReference type="GeneID" id="9684089"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58416"/>
    <dbReference type="eggNOG" id="KOG2562">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LANEHSE"/>
    <dbReference type="OrthoDB" id="5586at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095:SF0">
        <property type="entry name" value="MIP22305P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095">
        <property type="entry name" value="PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="697"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="525"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="394"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="801" mass="82771" checksum="63213A8C1AF19A30" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSD3</accession>
    <name>C1MSD3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucosidase II subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_27057</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; N-glycan metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058660.1">
        <property type="nucleotide sequence ID" value="XM_003058614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSD3"/>
    <dbReference type="STRING" id="564608.C1MSD3"/>
    <dbReference type="GeneID" id="9684472"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27057"/>
    <dbReference type="eggNOG" id="KOG1066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TVHQPLW"/>
    <dbReference type="OrthoDB" id="3237269at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090599">
        <property type="term" value="F:alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06603">
        <property type="entry name" value="GH31_GANC_GANAB_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000039">
        <property type="entry name" value="Glucosidase, alpha neutral C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000023">
        <property type="entry name" value="neutral alpha-glucosidase AB isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF54">
        <property type="entry name" value="BCDNA.GH04962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="13">
        <location>
            <begin position="12"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="12">
        <location>
            <begin position="212"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="14">
        <location>
            <begin position="548"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH57115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="796" mass="88784" checksum="69037590C73F26AE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSE8</accession>
    <name>C1MSE8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_47421</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058667.1">
        <property type="nucleotide sequence ID" value="XM_003058621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSE8"/>
    <dbReference type="STRING" id="564608.C1MSE8"/>
    <dbReference type="GeneID" id="9684480"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47421"/>
    <dbReference type="eggNOG" id="ENOG502QV2M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EANYASH"/>
    <dbReference type="OrthoDB" id="2096280at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="404" mass="43167" checksum="F074A6801C5419CD" modified="2009-05-26" version="1">MHRRYRKSTLHQPGTRIVHPGAADDAIPEHIVFGAATIPSEPVGDVIASYPSSELARWTLDRSEDVYASVRREPLGRGYTRGHALPDGLGTTKGFGVDGEVAPTSSVVNGLIFPKDTEYLAGDAETSDAHKMYVKTHGNYAPGEQKRRDYDWAAAGVDPNATTFGAVDTAKYDQFEGVAKALNPLKDETMPHYSASIVDARVEAFNATNRDELGKVKNLGLGEEIPDGHVFGAPSRKTIEWDAGKLIKGDYSEEAQLPDADLGKSMKHQGYVYDPSDGSAAALPAGADPSRAFGVPSTRRDLAAIRDKSTRSVADVTNYGDEPSASAIIFPPNGADRGVEEGDYLATYDAEALRALYATTGIEVGTEEAFASAFERAKALDGTPGGCTIGTFQRVRMYDAAAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MST4</accession>
    <name>C1MST4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_57814</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058379.1">
        <property type="nucleotide sequence ID" value="XM_003058333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MST4"/>
    <dbReference type="STRING" id="564608.C1MST4"/>
    <dbReference type="GeneID" id="9684174"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57814"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="509488at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="333"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="403" mass="45288" checksum="BF788D9C7FA24C65" modified="2009-05-26" version="1">MPKVKYPRKIRELVKKANAGCGEAAWAIARHYDNGSGGVEKNEALDVQWTEKSAALGYSLAQLVLGVRMRDKGDYTSARAWFEKSAAGGVEGVAEFALGSLYYEGQGVEKNPATAIEWWRAGALKGGVHAQYNLGAVLSDYLHEYTDAVLWLEKAAAQGFVDAMDRVGNLYFCGDGVERNARTAMIWWLKASRGGSVMAKENLLKKFRHGDFIGIESAYVLHENLFVELAEYGDEDSVQRLNRLRKNKRGTLLVTAKRTGLELSEDAVERFVSGPLPEHEAKNTFHHLALCFLHGRCGLEKNLRMAKEVFKECEIYDPDNAAVAEELVKLRSCVTCGKTDARWGCKLCRGVRYCNKRCQQRDWNRGEPPHKETCSRVVHMYPPGHFADLRTYWYHAKKRGESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSX4</accession>
    <name>C1MSX4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="2">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_16788</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="2"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058757.1">
        <property type="nucleotide sequence ID" value="XM_003058711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSX4"/>
    <dbReference type="STRING" id="564608.C1MSX4"/>
    <dbReference type="GeneID" id="9684196"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16788"/>
    <dbReference type="eggNOG" id="KOG2529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VDKPSGF"/>
    <dbReference type="OrthoDB" id="9995526at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767:SF2">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="TRNA-PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="5">
        <location>
            <begin position="26"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA pseudouridylate synthase B C-terminal" evidence="6">
        <location>
            <begin position="179"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="242" mass="26269" checksum="25F05D76AD34CE17" modified="2009-05-26" version="1">MVLLVDKPRGYTSFDVVARVRGIARRMGVKKVGHCGTLDPMATGVLVLCVGQARSVSPWSPYDRAYVGTMKLGERTPSQDADTAPDATFPWEGIADDELRDAAAKLVGDLKQAHDPQLPPMYSAIKVKGKRLYESARKGEVVERKTRDVRVDAFEVERDATNRQLVHFKVECGKGTYVRTLAHDLGESLGSAAHLTALRRVRVGEYDVDDAWTIDMLNDACAPMVEAAEDAKAAAAAAAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSZ1</accession>
    <name>C1MSZ1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_47246</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrion-specific ribosomal protein mL54 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058766.1">
        <property type="nucleotide sequence ID" value="XM_003058720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSZ1"/>
    <dbReference type="STRING" id="564608.C1MSZ1"/>
    <dbReference type="GeneID" id="9683863"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47246"/>
    <dbReference type="OMA" id="HARCIRY"/>
    <dbReference type="OrthoDB" id="567753at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013870">
        <property type="entry name" value="Ribosomal_mL54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08561">
        <property type="entry name" value="Ribosomal_L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="155" mass="16919" checksum="94F633A949853CB5" modified="2009-05-26" version="1">MSALLRIAAASAASTSGGLFSSLLASQTRAFVAPASALYAKAKTKAAPAAAKKEEPKATSAPTHAAGINFKKTGSDPEFGPDESYPDWLWTLLEPRKTLRQLENEVAAAKAMHEQSLADGKGPRYDIMDVKDIQRLLKLRRRVKIKENNDRRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT23</accession>
    <name>C1MT23_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57912</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058784.1">
        <property type="nucleotide sequence ID" value="XM_003058738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT23"/>
    <dbReference type="STRING" id="564608.C1MT23"/>
    <dbReference type="GeneID" id="9683769"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57912"/>
    <dbReference type="eggNOG" id="ENOG502REVD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="494993at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="872"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1050"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1074" mass="117836" checksum="8C76D3BA4E4275D8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTB7</accession>
    <name>C1MTB7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">T-complex protein 1 subunit eta</fullName>
            <shortName evidence="9">TCP-1-eta</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-eta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_44294</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterooligomeric complex that forms two stacked rings.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058459.1">
        <property type="nucleotide sequence ID" value="XM_003058413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTB7"/>
    <dbReference type="STRING" id="564608.C1MTB7"/>
    <dbReference type="GeneID" id="9684277"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44294"/>
    <dbReference type="eggNOG" id="KOG0361">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HRKGNTW"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03340">
        <property type="entry name" value="TCP1_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000022">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000006">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012720">
        <property type="entry name" value="Chap_CCT_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02345">
        <property type="entry name" value="chap_CCT_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="526"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="546"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="561" mass="60855" checksum="FE16039610C57E0E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTD8</accession>
    <name>C1MTD8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58034</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058847.1">
        <property type="nucleotide sequence ID" value="XM_003058801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTD8"/>
    <dbReference type="GeneID" id="9683910"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58034"/>
    <dbReference type="eggNOG" id="ENOG502SGX6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FMSMFDD"/>
    <dbReference type="OrthoDB" id="498232at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027973">
        <property type="entry name" value="FSAF1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15375">
        <property type="entry name" value="FSAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="389" mass="41064" checksum="7C608AD46A99BE5C" modified="2009-05-26" version="1">MATVPTKKKKKNKKSARDAGDAASMLAMHGAKFMSMFDDADDDAAARPRNEKKRKRAMSAGDDDAGDDDDDDDDALDGGDDGGAKTKTKTKTKTTKGDGDGDGDDDDAARVRTAARASSSSSTRAKDAAAAAAVETVVFGGDRPNAHASRSQASASGHVVGVSRAKKLFMSDKVGLVHEVASNPNRGGRPEAAAAAASATTKSGKNSEMENSEMGRVEGLTGASLNDMRRKVQNFGAQGLNKWDRRALDARQKTENNQKAERGVRIPMHIGVGMWKKNEEREEAKRQEDFEAGGRLMKKKRGLRKADSAEAKAKEGRDRGLAWGAGSFRGGVLTLKKSDVQKESERLNTKIMLGGGKLAGGDRPRGGGKGGKKSKGGSSSSRGGKRGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTG6</accession>
    <name>C1MTG6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_2626</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>K(+)(in) + H(+)(out) = K(+)(out) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:29467"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Na(+)(in) + H(+)(out) = Na(+)(out) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:29419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058860.1">
        <property type="nucleotide sequence ID" value="XM_003058814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTG6"/>
    <dbReference type="STRING" id="564608.C1MTG6"/>
    <dbReference type="GeneID" id="9684299"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2626"/>
    <dbReference type="eggNOG" id="KOG1965">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HRVESND"/>
    <dbReference type="OrthoDB" id="196264at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF187">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 11" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="240"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="13">
        <location>
            <begin position="11"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH57315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="416" mass="44925" checksum="FF3C173B1DB91A83" modified="2009-05-26" version="1" fragment="single">FLLLLVCLACAFVLGLVIKHFKITFLHEAGAALLMGMGVGLALWAANTSGSVTEWVDFNEEIFFFLLLPPIIFESGFSLSTRDFFNNFGGICALAFGGTLISTAVIGLCVWIFGAIGLITYLPFLHSLVFGALVSATDPVTVLALFQELGVNIDLYSLVFGESVLNDAVAIVTYRALINFHQDGVSFVSLITAIAFFGYIFVGSVLVGTFFAVATTIFFKLIGGPLLASHTHIEASLVMIAPYCAYTAAESVSLSGIVAILFCGIVMAHYTRPNLSPESQKNTKEIFKTLATLAETFVFIYMGVAMFLENQAWKSIPFAIVALLACMGGRACNIFPLTKKINAWRSPGRQIPENHVHMLWICGLRGAIAFALASSTIRDLGVESGRVIRTATLMIIIFTVLTIGGACSYLVDRLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTK7</accession>
    <name>C1MTK7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_68191</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058878.1">
        <property type="nucleotide sequence ID" value="XM_003058832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTK7"/>
    <dbReference type="GeneID" id="9683948"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68191"/>
    <dbReference type="eggNOG" id="ENOG502RZQG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RWLAWPT"/>
    <dbReference type="OrthoDB" id="5130at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="366" mass="39373" checksum="DE56E40AEF551F58" modified="2009-05-26" version="1">MQVIQRDKFRNERVFPLQSLRQAARVAVVYGDAEKVAKDLAAATPYRRRLEQSRILVVPVVDRGDKRGQGASSDAVADVGPGRWELLKDVVVAWPGAGAGRWLAWPTKNDAWAGYFRRLLLSAGAKNAAGGYVTVGVNGQVRGSGSGSPSWDVLLSTFPRNRPGNKADAAAEAAWRSATVDYQGDLSVNDPAMKDIRGDGAARPIGTTLELPSDGPAREVLKVHDAFYDALSRGDEAAMAAAWRGGERKKPSPLERFIERGAVLDGWATVLRPDRRPEGLKLSDVDVTIERDVATVSVLESVGNGATLLATQTYDKTDSDEGAGWTLRSHYTIPYGKDTVAKIALRCDERGCVAVPAKAVASEPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTW4</accession>
    <name>C1MTW4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_69378</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059389.1">
        <property type="nucleotide sequence ID" value="XM_003059343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTW4"/>
    <dbReference type="GeneID" id="9684519"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69378"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="302" mass="32222" checksum="AA79D7F34B2E9613" modified="2009-05-26" version="1">MPRRRRHRRQSSVPASRRRRHAGRRRDVGLPERVRAARGGGGSRRRGRRRERVRHRVVIRRHRPEEIVEGHLARRRRHRRGDGLEAIPRVRGERLLRDGRRAHAPVVRDDLWSDVERVDDRRGPLGGEVDEIRGRAAARAAVRAVSASGGAAALPSAVPIAPSDANSAAFASGSALEISTKMSYRSSAAPMSSFSDNADISNPSSLTLCTSDTTRGRIARHCALSSAISSALTSCDSGGYDRYGSIPAIMSRRTPTEFAATAMSSLSLATASGEDESTGSASAGGGCSSLALAANAAAMSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU89</accession>
    <name>C1MU89_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58711</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059454.1">
        <property type="nucleotide sequence ID" value="XM_003059408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU89"/>
    <dbReference type="GeneID" id="9684594"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58711"/>
    <dbReference type="OrthoDB" id="10572047at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="302" mass="30615" checksum="3763BD9205959192" modified="2009-05-26" version="1">MASSVSALHGAALARAMASKRSAFATSASDSSSSSSNKTSGFGYRRRRPSTSAPRRAVARPRAMASDGGDDEGFLSKINPFKAVAKAKEKSAIAKREADKNSIINDDLRKQLFGDGLLGKVAAGVINNAAGALKNQMAESMEASQEAYDAATRAVRMDAATRERLGGDMTFTPPMSQMSSSMNVNGVTRQSVQIGFIAQSARGDGRSASCNATGVSDGSAGGRMEVEVDVRFDDGGLIKVAGGGGGDFGGGAAGDVEVLSGGGDGGGSSRASSYGGSSSASSAVIDVDVETIDVDVDDVEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUH4</accession>
    <name>C1MUH4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SNF2 super family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_47521</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059494.1">
        <property type="nucleotide sequence ID" value="XM_003059448.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MUH4"/>
    <dbReference type="GeneID" id="9684639"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47521"/>
    <dbReference type="eggNOG" id="KOG0298">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KAVFFCA"/>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052583">
        <property type="entry name" value="ATP-helicase/E3_Ub-Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048686">
        <property type="entry name" value="SHPRH_helical_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21325">
        <property type="entry name" value="SHPRH_helical-1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="1473"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="392"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="610"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="841"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="899"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1741"/>
            <end position="1776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="400"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="899"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1747"/>
            <end position="1762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1776" mass="189869" checksum="6700386B13A35CD6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUJ7</accession>
    <name>C1MUJ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58834</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059506.1">
        <property type="nucleotide sequence ID" value="XM_003059460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUJ7"/>
    <dbReference type="STRING" id="564608.C1MUJ7"/>
    <dbReference type="GeneID" id="9684946"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58834"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NDCLERW"/>
    <dbReference type="OrthoDB" id="2018540at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029159">
        <property type="entry name" value="CA109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038985">
        <property type="entry name" value="OPRN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37904">
        <property type="entry name" value="OS10G0566900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37904:SF2">
        <property type="entry name" value="OS10G0566900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15011">
        <property type="entry name" value="CA109-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="221" mass="24037" checksum="9F8053B7DC51C32D" modified="2009-05-26" version="1">MADALLGKYRSLYAKARVVLERWSAAQTRATNLVDSVASIYERLAHLSETSRYGPLADSFPDLPARTRDAQYAALDRVLAALEDELELFDDLANLLDKIQRDGSALVRALRPPPPFAGALRRAHQPSLAECALGLEDVWRAYHDEATLKRVVCDELVVDASVEDVKTMAKLFAAEANVDKEFIRMTLDRVPAQSTSAMNEGRRGGGGRGGAGGSPRTRGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUQ8</accession>
    <name>C1MUQ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Long flagella protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LF4</name>
        <name evidence="5" type="ORF">MICPUCDRAFT_40264</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059539.1">
        <property type="nucleotide sequence ID" value="XM_003059493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUQ8"/>
    <dbReference type="STRING" id="564608.C1MUQ8"/>
    <dbReference type="GeneID" id="9684678"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40264"/>
    <dbReference type="eggNOG" id="KOG0661">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RVKTYMY"/>
    <dbReference type="OrthoDB" id="2158884at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07831">
        <property type="entry name" value="STKc_MOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000271">
        <property type="entry name" value="MAPK/MAK/MRK overlapping kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000773">
        <property type="entry name" value="MOK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="4"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="303"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="460"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="355"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="528" mass="58320" checksum="0F5AE4D2081DDB14" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUY8</accession>
    <name>C1MUY8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_69702</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059583.1">
        <property type="nucleotide sequence ID" value="XM_003059537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUY8"/>
    <dbReference type="STRING" id="564608.C1MUY8"/>
    <dbReference type="GeneID" id="9685023"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69702"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052048">
        <property type="entry name" value="ST_Response_Regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43228">
        <property type="entry name" value="TWO-COMPONENT RESPONSE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43228:SF1">
        <property type="entry name" value="TWO-COMPONENT RESPONSE REGULATOR ARR22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="182" mass="19974" checksum="A8204F6E2353816D" modified="2009-05-26" version="1">MSVLIVDDDVVNVKILKRAFVKNGDDVTTGEDGQDVVRLLLNESKRYDVVLLDENMRHMNGSAAVEETRRHEASAGDDPDGGERWSQLVVATTGNAAMSDKSKYQKAGFNGVLQKPMKLSTLVRWVHDFHAFWRATGGGKWTPGDPVPAGCVAPTISDASAHEDGYFIGDLEVFGTKLRREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV63</accession>
    <name>C1MV63_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubulin-specific chaperone A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_27395</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TBCA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059611.1">
        <property type="nucleotide sequence ID" value="XM_003059565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV63"/>
    <dbReference type="STRING" id="564608.C1MV63"/>
    <dbReference type="GeneID" id="9684761"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27395"/>
    <dbReference type="eggNOG" id="KOG3470">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VIQECIM"/>
    <dbReference type="OrthoDB" id="296187at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004226">
        <property type="entry name" value="TBCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036126">
        <property type="entry name" value="TBCA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02970">
        <property type="entry name" value="TBCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46988">
        <property type="entry name" value="Tubulin chaperone cofactor A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="115" mass="12740" checksum="EE92CBB512ABD600" modified="2009-05-26" version="1">MTADNREATRALKIKTGVLTRVRRELAMYSDEVAKETAKLETMKAEGRDPHDVRQQDQVLGESSMMIGDCKTRMENAFNELLAATEEHGEECADSEELAVAKALLDEVEPTLEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVG5</accession>
    <name>C1MVG5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Pyruvate, phosphate dikinase</fullName>
            <ecNumber evidence="3 11">2.7.9.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PPDK_1</name>
        <name evidence="19" type="ORF">MICPUCDRAFT_27547</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>pyruvate + phosphate + ATP = phosphoenolpyruvate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10756"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.1" evidence="3 11"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060034.1">
        <property type="nucleotide sequence ID" value="XM_003059988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVG5"/>
    <dbReference type="STRING" id="564608.C1MVG5"/>
    <dbReference type="GeneID" id="9685187"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27547"/>
    <dbReference type="eggNOG" id="ENOG502QREJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HFFHEVG"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050242">
        <property type="term" value="F:pyruvate, phosphate dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000038">
        <property type="entry name" value="Pyruvate, phosphate dikinase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.10">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.189.10">
        <property type="entry name" value="Pyruvate Phosphate Dikinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010121">
        <property type="entry name" value="Pyruvate_phosphate_dikinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004531">
        <property type="entry name" value="PRK05878.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01828">
        <property type="entry name" value="pyru_phos_dikin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE DIKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931:SF9">
        <property type="entry name" value="PYRUVATE, PHOSPHATE DIKINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000853">
        <property type="entry name" value="PPDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="17">
        <location>
            <begin position="66"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="17">
        <location>
            <begin position="113"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="17">
        <location>
            <begin position="349"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilising enzyme mobile" evidence="16">
        <location>
            <begin position="467"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilising enzyme C-terminal" evidence="18">
        <location>
            <begin position="565"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="12">
        <location>
            <position position="500"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="880"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="606"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="663"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="792"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="792"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="815"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="816"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="817"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="818"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="818"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH55986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="926" mass="99798" checksum="7E3D8BF3629B4DD7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVM3</accession>
    <name>C1MVM3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_34222</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060062.1">
        <property type="nucleotide sequence ID" value="XM_003060016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVM3"/>
    <dbReference type="STRING" id="564608.C1MVM3"/>
    <dbReference type="GeneID" id="9685500"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34222"/>
    <dbReference type="eggNOG" id="ENOG502S497">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AMTQKMY"/>
    <dbReference type="OrthoDB" id="193300at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051493">
        <property type="term" value="P:regulation of cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000059">
        <property type="entry name" value="RIKEN cDNA 6430531B16 gene"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010441">
        <property type="entry name" value="CH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052111">
        <property type="entry name" value="Spermatogenesis_Ciliary_MAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12509:SF9">
        <property type="entry name" value="SPERM FLAGELLAR PROTEIN 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12509">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06294">
        <property type="entry name" value="CH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="2">
        <location>
            <begin position="9"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="211"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="252" mass="28419" checksum="DB14D07FF43BBA84" modified="2009-05-26" version="1">MTYISAVSEAELKILYQWVDQIPLSRPKRNIARDFADGVLMAEVVAHFYPKLVELHNYSSASAMTQKMYNWNTLNAKVFRKLDFTLDPTHLKDLCTHKTGAVEYALKLIKHYLGEFQKNNGVVKKQNMKGGVAPPPVDFHKAGEEVKEAFGFVVTDHKIKPGMLEQNIMLPTVGDGAVNPETGEEMAQQPQGELLRYEDPTGEMIKKDLLIAELRETNAILDTKARKLEQLVRLKEAKVQTLLNKLQALSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVN1</accession>
    <name>C1MVN1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59439</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060066.1">
        <property type="nucleotide sequence ID" value="XM_003060020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVN1"/>
    <dbReference type="GeneID" id="9685221"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59439"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="308"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="412" mass="44744" checksum="BE756B1552E63BF8" modified="2009-05-26" version="1">MGLFGKSKKKKPQPASQESSIRADLRKMRSPVRSPSPPRGKARVSSPGPRARVTSMSPPRGRRVASPSKSSRGRSRSKSEGERESAKSPRPPLRFASPPRLPTNPVAPSFVDREPPSRVVRCMECMDGAVIRKKEAAWAKERAEWARTMSEARRLNNQLRRRVVVAEAKAVAPDELAKTKKKLLKANAEHKKVAARFNAAASKDRMLQHAAQKIKDAEKDAKMHALAARVVAAEKSAAAADESLRVALEKLDAITRQASANYECAVEMGEHVRKMERERAAAIERAESLEANAAEAEEKVRAVERLAEAAGDAEERRRRHALMDRLGVGTSLGGGSDGGDEDGGDAPLELDAIEMLAAADERDAAREASDLVGFDLDLAPPSPPPSPGPPAKSKKRSWFSPSKKKQRPRVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVS7</accession>
    <name>C1MVS7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59490</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059800.1">
        <property type="nucleotide sequence ID" value="XM_003059754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVS7"/>
    <dbReference type="GeneID" id="9685239"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59490"/>
    <dbReference type="eggNOG" id="ENOG502S3Y4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DESTWTM"/>
    <dbReference type="OrthoDB" id="496827at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="2">
        <location>
            <begin position="282"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="384" mass="40160" checksum="05040FBC9E978FF6" modified="2009-05-26" version="1">MTTDDAPAPEEPLTTTAEKEAWLRERGVEIESAADRASKAAARNQKKPATTTTIDGASSASAHTRAFTYVLIPADDAKPFEERVAIVDADAPPSDALVEILRPVFAGGGGIDARAAREQAVRQFGEKGAAVTAAALENVAADGATETFALVRPSDANGERGVSLYLDEVGLLKGSPHNARASALARACGYDDVDIRGDVFAGAIGITRDGERVSADFRVSELDGDAAWLKAAKAENYEHGMKMKKFQESLGDRAGGLVSGGIDMTGGGGNGGGMPGGPGVDMNGNAFAWCQTDDEVEIMVDVDADIVAKDVVVTFRPDGFAVRARDEVMLAVPSLFRKTRPDECTWTLERGGGGEGGEGEGARGRVVATLAKMDEEVWDALKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVU6</accession>
    <name>C1MVU6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59512</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059812.1">
        <property type="nucleotide sequence ID" value="XM_003059766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVU6"/>
    <dbReference type="GeneID" id="9685539"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59512"/>
    <dbReference type="OMA" id="DHAKTHR"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="524" mass="54538" checksum="6D6422E673E86A84" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVW1</accession>
    <name>C1MVW1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59531</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060108.1">
        <property type="nucleotide sequence ID" value="XM_003060062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVW1"/>
    <dbReference type="GeneID" id="9685259"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59531"/>
    <dbReference type="OMA" id="LPAEPCC"/>
    <dbReference type="OrthoDB" id="1045822at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="178" mass="19167" checksum="9396DF155F19CFEC" modified="2009-05-26" version="1">MAKPYYPPPPGQAPAPTYGYAQPQPVMAQPVMQQPAMVMMQNAGLGFWKASLCECQSDCGLCMASCFLPCCVHGSNANMRRDARFIGPMEGCNGECICYAIGCYARPLYAICGMSGRGNHRAKYNIAGGCCGDCCTHLCCYSCAVGQEYLDLKKRLEPPQQGMMGGVMMSQPGAVIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVW6</accession>
    <name>C1MVW6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_59536</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059822.1">
        <property type="nucleotide sequence ID" value="XM_003059776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVW6"/>
    <dbReference type="STRING" id="564608.C1MVW6"/>
    <dbReference type="GeneID" id="9685549"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59536"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="73"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="339"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH55774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="365" mass="39111" checksum="22DDA7F10A306BAF" modified="2009-05-26" version="1">MDRPPSSRQRSRARSRDPVSKLAVSTTRRAERTARAMMRAAAWTTAPTPTPAAGVRPFARARKTTTRALPLIQAAHRQHHRRRRPPPPLSDEPRARRRRASATTRAVTTREDEAATATADDDDGGDAADAASSSPVERDENDIECIAWGAGAYDPGLDESLLSESRCDLTTAVKFRRDAEWREYQSPSRYFQQLTTINGSVVARRVAAPAIAVAAWAAAVAFAVKSGLAWTAGMTAAAATATPFLSVVGGAVSLLIGFRTNAAYGRFCDAADSFADVLGSVRNLSRKLAVWCPEADRARMAALVAALPWAVKARGQGVEGSADATMRLRRILTPTGQFESIEPTGNVPAQARSPYTGSHTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW59</accession>
    <name>C1MW59_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59636</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060159.1">
        <property type="nucleotide sequence ID" value="XM_003060113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW59"/>
    <dbReference type="GeneID" id="9685306"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59636"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="144" mass="15937" checksum="48A3BD6FD680C0A1" modified="2009-05-26" version="1">MDEGKPGRHDERPRARDNFDPRPPFGGDPKMVRALADDIFMDGKMQLHAGADTESGLGPGLVPTSEASRGGDDIFAEGRAREHSEKDTHSWLEMTESGVVPGEGAPVQRPSHVRTYHGPPMDAERAGLVKRAEEDDLDPRHRYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX03</accession>
    <name>C1MX03_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_59315</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060011.1">
        <property type="nucleotide sequence ID" value="XM_003059965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX03"/>
    <dbReference type="STRING" id="564608.C1MX03"/>
    <dbReference type="GeneID" id="9685100"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59315"/>
    <dbReference type="eggNOG" id="KOG1867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FRTRTVH"/>
    <dbReference type="OrthoDB" id="47475at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF33">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="13">
        <location>
            <begin position="210"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="149"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="305"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH55963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="585" mass="60742" checksum="346B1DF49DB5C2B3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXG0</accession>
    <name>C1MXG0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_70283</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060390.1">
        <property type="nucleotide sequence ID" value="XM_003060344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXG0"/>
    <dbReference type="GeneID" id="9686123"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70283"/>
    <dbReference type="OMA" id="YFAKEAN"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031432">
        <property type="entry name" value="MGP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36013">
        <property type="entry name" value="ATP SYNTHASE 24 KDA SUBUNIT, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36013:SF2">
        <property type="entry name" value="ATP SYNTHASE 24 KDA SUBUNIT, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15704">
        <property type="entry name" value="Mt_ATP_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="257" mass="27648" checksum="43B6A9C48991620F" modified="2009-05-26" version="1">MLALRIARNLSRSAPAAVNAGVSRAFASSRIAANEAGAGEGDPVKDVFTRVQRDFRRLMDATPGVKVPVGGSEEEIAKFAWKRYDAAYELGIQSPEELAADVAEALRKPGQSAKQYLEKVDEHRERFGFEDTDGLSAALKTAVAEIEKKTGQTLMVDDEAGMAKLAETVAPLVENVMSADEDALESASIEEAAAEELAELAELKKSMRPPQIDAKTGQPKERATTEQIVARAKEAIESGRLKPAQAESLRKLLAQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXG2</accession>
    <name>C1MXG2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycolate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GOX2</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_19011</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060687.1">
        <property type="nucleotide sequence ID" value="XM_003060641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXG2"/>
    <dbReference type="STRING" id="564608.C1MXG2"/>
    <dbReference type="GeneID" id="9686124"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19011"/>
    <dbReference type="eggNOG" id="KOG0538">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WSYVAGG"/>
    <dbReference type="OrthoDB" id="25826at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000029">
        <property type="entry name" value="L-lactate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF149">
        <property type="entry name" value="2-HYDROXYACID OXIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 7" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="8">
        <location>
            <begin position="8"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="422" mass="45782" checksum="7267D66500EBD612" modified="2009-05-26" version="1">MLNAPSARRLESAVNIADLRLAARQRAHRMVFDYLDAGADDEITLRRNKDAYSSLELHPRVLAGLKPPLDLSARFMRSECALPFFVSPTAGSKMFHADGEQGVARAAAKHGVMYSLSTMGTSAPAEVAAAIPPKHPKLFQLYVWKDRALVRDMLRQAMDNGFDALALTVDLTWYGNRERDVRNGFTVPPAYTLRQIADAVRAPAWSWDFLANEEYAYAAVKLAAEGAFYTLVAFIRDAFDPSFDWDDAEWLVNEWGDRGPVALKGVLTPEDARLAVERGFDAVWVSNHGGRQLETSPAAIDVLPNIRDALGGTGLAVELVVDGGVQRGTDVLKGLALGADAVALGKPYLYGLGAGGEAGVDRAFTILRDELERAFGLLGVGTTAELRRRIGRGEGLVRRRGVSARDFPDPGAAERGWGGGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXR4</accession>
    <name>C1MXR4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle 14 kDa protein</fullName>
            <shortName evidence="7">SRP14</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_11942</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SRP14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060443.1">
        <property type="nucleotide sequence ID" value="XM_003060397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXR4"/>
    <dbReference type="STRING" id="564608.C1MXR4"/>
    <dbReference type="GeneID" id="9686174"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11942"/>
    <dbReference type="eggNOG" id="KOG1761">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SVTMKRM"/>
    <dbReference type="OrthoDB" id="19209at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.10">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, srp9/1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003210">
        <property type="entry name" value="Signal_recog_particle_SRP14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009018">
        <property type="entry name" value="Signal_recog_particle_SRP9/14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12013">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02290">
        <property type="entry name" value="SRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54762">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, SRP9/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH55212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="107" mass="12238" checksum="EF8028509E4800EF" modified="2009-05-26" version="1" fragment="single">VLLENDAFLTGLTQLYERNRASGSVWVTMKRSMMRKLPKRNAPNAPTPEEVMDRDGEVWVTLVRATDGKRKISTTVTKNKAEKFAKSLNTIQRAFIELQEDDAKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXZ0</accession>
    <name>C1MXZ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60337</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060473.1">
        <property type="nucleotide sequence ID" value="XM_003060427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXZ0"/>
    <dbReference type="GeneID" id="9686220"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60337"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="431" mass="46533" checksum="B49A4CF8B1AF6274" modified="2009-05-26" version="1">MFRTARIASRAWNAPCARGMCAGPSVGERDGRDGDDASPSSRDEEPSETRRDPPAGAPRVLLDFLVRDRDALPRSPFSSSPPFASPPRDPGASETEASASTDDGAKLGPDGKPWVPPEEIASVAFGSPVRYPLTRGDKSRGYPKMNVAEMCAEIRGRISAKQMPGERHLQQLVDKVTTKEEASAAAETIAQFHHARVRDPKFGAKSRLSGQSMNMFVSACERSGNVTAAVEALEMHNALGFRLTKTVCVKVLRFVESAEGELALTMRVYRTMREGKIGLGTDGVIVNLIVRAAVRAKAFEVARDWLKKFADAAVPVHLKNYVAVMQPAIDLGLATFVIDMHDTMTCKPPNNAFSLLSKAMAHLYLDEPDAAARAFEAAVEGAIAMERRETERAGGGGGGDDATDDVDPHRAGHVPVRTSFARILEAWPRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY41</accession>
    <name>C1MY41_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">molybdopterin molybdotransferase</fullName>
            <ecNumber evidence="2">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CNX1G</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_60392</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="2"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060806.1">
        <property type="nucleotide sequence ID" value="XM_003060760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY41"/>
    <dbReference type="STRING" id="564608.C1MY41"/>
    <dbReference type="GeneID" id="9685939"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60392"/>
    <dbReference type="eggNOG" id="KOG2371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NCLAKWM"/>
    <dbReference type="OrthoDB" id="4349954at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3340.10">
        <property type="entry name" value="SMc04008-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051920">
        <property type="entry name" value="MPT_Adenylyltrnsfr/MoaC-Rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023163">
        <property type="entry name" value="SMc04008-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036810">
        <property type="entry name" value="SMc04008-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43764">
        <property type="entry name" value="MOLYBDENUM COFACTOR BIOSYNTHESIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43764:SF1">
        <property type="entry name" value="MOLYBDOPTERIN MOLYBDOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06844">
        <property type="entry name" value="DUF1244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158757">
        <property type="entry name" value="SMc04008-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01078">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaB/Mog" evidence="5">
        <location>
            <begin position="192"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="106"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="116"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="354" mass="36923" checksum="38045A0805047676" modified="2009-05-26" version="1">MVDAQTTEKIEAYAFRALVAHMRERADVSNIDQMNLAGFCRNCLAKWYLVGARKNGDAAMRYDDALERVYGEPYGDWKKKHQTKATDAQMESFEKNKHLHAKHDEAALRDPPPPAAAAAAAPSEKIPTTTTTTTPSTSNAPTASPPPPPPLAARGGASSVCCEPADALAAAAAATASTSTATGGVPTSVRLGVVTVSDRAFDGEYEDVTGPALVCQMTAAAAEPKDPGGHGFTLFSHQRVVVPDDARKIAAAIKTLAASGCNLVLTTGGTGLSSRDVTPEATTSVLHKLAPGIPEAMHRAAVDRGVPHAMLSRSAAGVRDRCLVINLPGRPHAARDDLDVVMPVLAHAISQVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYI7</accession>
    <name>C1MYI7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40821</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060573.1">
        <property type="nucleotide sequence ID" value="XM_003060527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYI7"/>
    <dbReference type="GeneID" id="9686011"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40821"/>
    <dbReference type="OMA" id="KAFTWEA"/>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317">
        <property type="entry name" value="BLR8090 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317:SF1">
        <property type="entry name" value="ZINC-RIBBON DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="35"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="109"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="189"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="269"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="336" mass="38396" checksum="E5047358BF3FBDA1" modified="2009-05-26" version="1">MPKKRQTRPGKPFIEWCAENGKRGERLANEFREELPTELTFASNYKAKWKCLKCKHVWRAQVCNRTKSDRPSGCPKCCLSRGQGCQTVVSRTNNFLAWCEKNGELGKKLSREYVDKDKPPTAVTKASMYKALWKCSNVECKHVWRTQVCNRTRSNRPGGCPMCANNAPASKTNNFLAWCEKNGELGKKLSREYVDKDKPPTAVTKASMYKALWKCSNVECKHVWRAEMCNRTRSNRPNGCPECANHRPLSKTNNFLAWCEKNGELGKKLSREYVDKDKPPTELTFASHYKAKWKCLTCKHVWRAGVSSRTNNVKPTGCPKCNLVGGSQSEKRKRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ81</accession>
    <name>C1MZ81_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_19637</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="11"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061169.1">
        <property type="nucleotide sequence ID" value="XM_003061123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ81"/>
    <dbReference type="STRING" id="564608.C1MZ81"/>
    <dbReference type="GeneID" id="9686608"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19637"/>
    <dbReference type="eggNOG" id="KOG0831">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FWFTCAN"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF63">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH54819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="334" mass="36328" checksum="AD5C2C7825B53196" modified="2009-05-26" version="1">MTAAPASARDPALATGSGSLYNHLMMFAWLGVVHAVVALVAVACYFLPHPVATCAIALVALAALTPVTTPHPAWGLAIARAITKAAVRYFPLTMEWEDERAYLDAAAKGVPAVIGLEPHSVLPLSIVAFGNYFFFTESTPECVRNSRALATGTIFVIPVLKHLWSWLGMDAISRRAMKTLLDDGRSVLIIPGGVAECLQMRPGVETIYLKKRFGFVKLAIQTGASLVPAFTFGQTRSYSYWRLGPPLVPHVVAEVFARACRVAPMVFWGKWGSPIPNMVPMHTVVGKPIPVKKQSEPSNEYVQEKLNEFVAAMESLYARHKGKHGYAESTLVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N017</accession>
    <name>C1N017_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48161</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061049.1">
        <property type="nucleotide sequence ID" value="XM_003061003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N017"/>
    <dbReference type="GeneID" id="9686757"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48161"/>
    <dbReference type="OMA" id="CPVETIT"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="511"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="272"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="368"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="617" mass="63728" checksum="7888A1306556DB7B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0E9</accession>
    <name>C1N0E9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_10422</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061625.1">
        <property type="nucleotide sequence ID" value="XM_003061579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0E9"/>
    <dbReference type="STRING" id="564608.C1N0E9"/>
    <dbReference type="GeneID" id="9686820"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_10422"/>
    <dbReference type="eggNOG" id="ENOG502QT30">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PWEQMKL"/>
    <dbReference type="OrthoDB" id="2016955at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050988">
        <property type="entry name" value="Mannitol_DH/Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013118">
        <property type="entry name" value="Mannitol_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013131">
        <property type="entry name" value="Mannitol_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43362:SF1">
        <property type="entry name" value="MANNITOL DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43362">
        <property type="entry name" value="MANNITOL DEHYDROGENASE DSF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01232">
        <property type="entry name" value="Mannitol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08125">
        <property type="entry name" value="Mannitol_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannitol dehydrogenase N-terminal" evidence="2">
        <location>
            <begin position="11"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Mannitol dehydrogenase C-terminal" evidence="3">
        <location>
            <begin position="302"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="477" mass="52211" checksum="40FAA444D4854EB4" modified="2009-05-26" version="1" fragment="single">PVFDRSETSTGIAHIGVGGFHRSHQQAYMNELLARDFDAAKTWLYTGVGVMPNDAGMRDYLRGNDWSYPIVARDGADGGELRATVEEVVTIRDMLLAYEDPVVAIEALADPAIKIVSLTITEFGYRVPLHKGDFALIDNALNGILGTDAFDLDSIAEECALEEECKAPTTFGLICAAAALRFERGIKPFTLMSCDNLPENGEVCKKRMTSAGEELVCGGLCAASLDAFVVWIQTAVKYPSTMVDRITPATSWEDIATLPERCGIEDEWPVMCEPYKHWVIEDNFVDDERPAWETVGAVVVKDVIPHELMKVRLLNVTHSAMCYAGILAGLTHVHEAVTHGKLRAYLETLMRDEISATLARNPGMDPALIPTFDAYGESVLKRFENVAVKDQLDRIAMDGSEKFRVQGRGVVLEGLALGLEMKGFAMYVAAWATFLAREVAEGREVKDAGGQQVTAAFQKGGTGIEAFLDMVDIFGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0V8</accession>
    <name>C1N0V8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51168</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061705.1">
        <property type="nucleotide sequence ID" value="XM_003061659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0V8"/>
    <dbReference type="GeneID" id="9687144"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51168"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="334" mass="35047" checksum="4A561C1B6AC169B1" modified="2009-05-26" version="1">MGASTSAMPAPCGRPPVTANPTTAKLTPRDASALRDLYGHDDELFQLMCGAELLRDCAKNVRDDAAAYFHAMSASCAAERKFGEKLQSVADTPNVSGVAAHLAAAARADDAEGETSPFPRGAAGGGGSDPRLRAALQVSASVGELARAEVDASAAHDAFVETFLEKMKDVAARVEKAHNTKLETAALAHEKAFRQVKPPEHRLEHLMNLDDEQRESPECQKKIDVAEVELEKRKAQVAATSKMLKIRARLFLDTYTPYVRDAISAFAVAQHDAHAAMARAIGRSVGGGGGGVDAARRECAWFLDAEPGAATPKVPVPSAVGEGGEGEIVAAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N100</accession>
    <name>C1N100_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51209</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061485.1">
        <property type="nucleotide sequence ID" value="XM_003061439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N100"/>
    <dbReference type="STRING" id="564608.C1N100"/>
    <dbReference type="GeneID" id="9687161"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51209"/>
    <dbReference type="OrthoDB" id="10673415at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="340" mass="36613" checksum="828079779BE55CA5" modified="2009-05-26" version="1">MPLFGWTSRARDAAAAASAASAAASPPPAPATPTRGSRDARRRGSSGDVVLSVDADNAAVSVPRELGAGERARASTPPPRLSAEEEEEEEEEEDAVDVELGEIRVVPADGASSEKEKGKKAEKKDDDEERYCRICMERIARAELDAGTATSLGCACVGGFAHVDPCAEQYANAKSDATCEVRVFFLAYFLVLVLSKHLTLARAQLCLENMDALDAIVAKLRASRRGRARGRRAILVLNDLPTGAGGRAIRSRENDAHGDPVFDVEDARLYRPGWGSRNPGMWLLWIITRPFVLVAYVSLYFVTCLVAAMAVPAVILFCPEFLDASFFFPDVSIQPEASPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1G1</accession>
    <name>C1N1G1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_51390</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol polyphosphate 5-phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061810.1">
        <property type="nucleotide sequence ID" value="XM_003061764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1G1"/>
    <dbReference type="STRING" id="564608.C1N1G1"/>
    <dbReference type="GeneID" id="9687249"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51390"/>
    <dbReference type="eggNOG" id="KOG0565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498967at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF275">
        <property type="entry name" value="LD06095P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="3">
        <location>
            <begin position="27"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="679"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="787"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="835"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="464"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="696"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="712"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="793"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="854"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="884" mass="89420" checksum="109951EFB2E5278A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1T1</accession>
    <name>C1N1T1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_11297</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062173.1">
        <property type="nucleotide sequence ID" value="XM_003062127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1T1"/>
    <dbReference type="GeneID" id="9687407"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11297"/>
    <dbReference type="eggNOG" id="KOG1971">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1736837at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24014">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24014:SF4">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25238">
        <property type="entry name" value="OGFOD2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="77"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="19351" checksum="A6CF91B1F8954DCF" modified="2009-05-26" version="1" fragment="single">VYAFDLFEERFCAMLTEEVDAYEVSGLPKRRPNTMNASGLIVNEIGMWGLMTDVVKALASPLAAALYRDEIFADSLDHHHSFVVHYARDKDTRLDMHHDASEVTLNVCIGRDHFEGAGLRFCGRFGDANHRSGPSFAVSHVPGRAVMHLGRQRHGADVIAAGERMNLIVWARSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1U6</accession>
    <name>C1N1U6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_35623</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061975.1">
        <property type="nucleotide sequence ID" value="XM_003061929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1U6"/>
    <dbReference type="GeneID" id="9687619"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35623"/>
    <dbReference type="OMA" id="VICKVCY"/>
    <dbReference type="OrthoDB" id="370932at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039713">
        <property type="entry name" value="At2g23090-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039438">
        <property type="entry name" value="At2g23090-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788">
        <property type="entry name" value="OS07G0114300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788:SF21">
        <property type="entry name" value="OS07G0114300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12907">
        <property type="entry name" value="zf-met2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="At2g23090-like zinc-binding" evidence="2">
        <location>
            <begin position="39"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="78" mass="8551" checksum="33DAC8EBAC5C3B9A" modified="2009-05-26" version="1">MGGGNAQKSAKARQMKQEKMKTASKGSQLADNAKAMNIQCKVCLQTFVSTTASVKLKEHADNKHPKNPYEQCFPNNPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2N6</accession>
    <name>C1N2N6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_21075</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061906.1">
        <property type="nucleotide sequence ID" value="XM_003061860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2N6"/>
    <dbReference type="STRING" id="564608.C1N2N6"/>
    <dbReference type="GeneID" id="9687557"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21075"/>
    <dbReference type="eggNOG" id="KOG0393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PRHKDVT"/>
    <dbReference type="OrthoDB" id="494635at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00157">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000983">
        <property type="entry name" value="Rho family GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH53618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="189" mass="20638" checksum="9C5F9B1207F8B338" modified="2009-05-26" version="1">MKVVVVGDGAVGKTSMLLCYTTNTFPTDYMATVFDNYAVNVQYGEKTINLGLWDTAGQDEYAQYRPLSYHEADGFILAFSLIDRASFENVSQTWIKELRAKAPGAPITLVGTKLDLRGSASGVDRGGARHVTTEEGEEMRRKIGAEAYVECSALTQDNLKRVFETAIDVHMRPKDVPAKKTGGCACVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N326</accession>
    <name>C1N326_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48506</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062536.1">
        <property type="nucleotide sequence ID" value="XM_003062490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N326"/>
    <dbReference type="STRING" id="564608.C1N326"/>
    <dbReference type="GeneID" id="9687976"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48506"/>
    <dbReference type="OrthoDB" id="423607at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="235" mass="25509" checksum="34F06AE5855A1132" modified="2009-05-26" version="1" fragment="single">MDREEEEETLAARRKKLKRKRADAQRADARAMTRAGLSFAEQSTRALPRDVLLRIFAMATELPADVADDARRSTHRTGAIPLVPKLASTCRAFRDVLRERPESVWRVVDLSYGWCRPSDAVIRRLCASGQWAKVHTLNLSGCATLTDKTYAALAKHCPELKHLDASGMGDKVTAGALASIAGRLESASLDHLSLSPARGGVRGATTYVASALTGRLKRLSIAALPWLGNDVLPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N375</accession>
    <name>C1N375_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_68566</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062558.1">
        <property type="nucleotide sequence ID" value="XM_003062512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N375"/>
    <dbReference type="STRING" id="564608.C1N375"/>
    <dbReference type="GeneID" id="9687773"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68566"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910735" evidence="2">
        <location>
            <begin position="25"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="363" mass="38128" checksum="7805A195F61AFA55" modified="2009-05-26" version="1">MRGVIAIAARRVLFVLVLALVASSSPRTLVDAASSSSSSAASSTTSTRGLTDASPLATRDGIPDASLCEHGDAGHRRATTMGDAHLKQRKPLLAEACYLGALRYKSDFPMALYGLGEAHVMADRDALAAEAYALAIDAWPQYVDARIALGELKARGGDAIAAEAAFRGAVAIAPTDALAWEALGKHLLSIGARDRAHDAYERASASVPGGRENVGLLFGRARVAAAKREWRACVESAAAASARAGGAFADAAFLSGECEARLGCAEASRAEKTEEEIADGERRVASGLRRMKDAIAMDDDEPGDGEEAEARRVTYATLLEECAKRDDAIDAVNDALRAHPDSEALRALRASLNAKRKREAGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N391</accession>
    <name>C1N391_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_48532</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062339.1">
        <property type="nucleotide sequence ID" value="XM_003062293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N391"/>
    <dbReference type="STRING" id="564608.C1N391"/>
    <dbReference type="GeneID" id="9688008"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48532"/>
    <dbReference type="eggNOG" id="KOG2476">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IVPITHY"/>
    <dbReference type="OrthoDB" id="444325at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061632">
        <property type="term" value="F:RNA lariat debranching enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07380">
        <property type="entry name" value="MPP_CWF19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040194">
        <property type="entry name" value="Cwf19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006768">
        <property type="entry name" value="Cwf19-like_C_dom-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006767">
        <property type="entry name" value="Cwf19-like_C_dom-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072">
        <property type="entry name" value="CWF19, CELL CYCLE CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072:SF4">
        <property type="entry name" value="CWF19-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04677">
        <property type="entry name" value="CwfJ_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04676">
        <property type="entry name" value="CwfJ_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cwf19-like C-terminal" evidence="3">
        <location>
            <begin position="380"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Cwf19-like protein C-terminal" evidence="2">
        <location>
            <begin position="541"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="613" mass="65622" checksum="6626B4B36679D0DB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N399</accession>
    <name>C1N399_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52090</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062572.1">
        <property type="nucleotide sequence ID" value="XM_003062526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N399"/>
    <dbReference type="STRING" id="564608.C1N399"/>
    <dbReference type="GeneID" id="9688012"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52090"/>
    <dbReference type="eggNOG" id="KOG1302">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TEEWHAC"/>
    <dbReference type="OrthoDB" id="10262287at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043155">
        <property type="entry name" value="VPS33_dom3b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="737"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="845" mass="90517" checksum="39544B9F4906AC02" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3E0</accession>
    <name>C1N3E0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RWD domain-containing protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_52139</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062594.1">
        <property type="nucleotide sequence ID" value="XM_003062548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3E0"/>
    <dbReference type="GeneID" id="9688034"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52139"/>
    <dbReference type="eggNOG" id="ENOG502RUZ9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GARCKER"/>
    <dbReference type="OrthoDB" id="498790at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902073">
        <property type="term" value="P:positive regulation of hypoxia-inducible factor-1alpha signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033235">
        <property type="term" value="P:positive regulation of protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038840">
        <property type="entry name" value="RWDD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15628">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15628:SF1">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="7">
        <location>
            <begin position="9"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="449" mass="47071" checksum="F71C7CCFFE2C9482" modified="2009-05-26" version="1">METLSRQLMELECLAAMYPDDAPATAAGAEIAMTRSDVDANADARTLLDAWDDGAGETPSDDALAALPRPRATLTIPVRRARRRDGDGDGVDDDRFDGGVVVLRATLPSEYPRAAPELELDCSSSALPRDVAASALARLRALAASRTTALGEDGGECLMELTQEASDLAAAAAADAAAAAAAAAAAADAGGGGGDDDGCQVAVVKIDHMNDSSGYVKKLKKWAAVGGLSARLFARDPSGGGGGGETASHTTPFAWCTPFLKDFSRRHSSPALPFQRLTGGGFPAGRVDGAYLILRGDGDAIKSFLAKLRVELVDVDSRGAKCRERKSTVLCLRDANAAKDGQARSITTLVPIRPRRRGERRSLRNFSPGASLRPSPLDPFDARPRRLTTSTDAFRLLPPSRQDAVPKFDGFLSTPYDSDAELEDMMSALNVLHVGSGATRFTATAASQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3G8</accession>
    <name>C1N3G8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52166</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062374.1">
        <property type="nucleotide sequence ID" value="XM_003062328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3G8"/>
    <dbReference type="STRING" id="564608.C1N3G8"/>
    <dbReference type="GeneID" id="9688050"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52166"/>
    <dbReference type="eggNOG" id="ENOG502SD8U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EKDPFGQ"/>
    <dbReference type="OrthoDB" id="275715at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20251">
        <property type="entry name" value="Complex1_LYR_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="2">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="100" mass="10974" checksum="11D05D6AE51C0529" modified="2009-05-26" version="1">MSASTLTLYRHILKAARTFPSRNRAGIIEDIKLEFRENRAVTDAAALRAKIALANDGLDRMRAYTGLDSGSSAWDVSLKGPFDGTNGMGEKEDSKREDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1N480</accession>
    <name>C1N480_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_29336</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062951.1">
        <property type="nucleotide sequence ID" value="XM_003062905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N480"/>
    <dbReference type="STRING" id="564608.C1N480"/>
    <dbReference type="GeneID" id="9688593"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29336"/>
    <dbReference type="eggNOG" id="KOG0745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RIYQKKP"/>
    <dbReference type="OrthoDB" id="1721884at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19497">
        <property type="entry name" value="RecA-like_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003745">
        <property type="entry name" value="PRK05342.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="3">
        <location>
            <begin position="68"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="4">
        <location>
            <begin position="276"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="371" mass="40768" checksum="5427957B3208924A" modified="2009-05-26" version="1">MKRLPTPKEMVKMLDEHVVGQTHAKKVLAVAVFNHYSRVRAEAEAASSSSSASSGAASCPTEAAWPADKSNVVLCGPTGCGKTLLAKTLASFVDVPIVIADATTLTQAGYVGEDVESLLYKLLQEARFDVELAERGIVYIDEIDKLTRKAENVAITRDVSGEGVQQALLKMVEGCVVNVPEKGGRKNPRGEFTQVDTTNILFVCGGAFSGLETQVRHRRAESLVGRRPVRPRRRRVPKRADADDALERVEACDFIAYGLIPEFVGRFPVAVPLRSLNEDELVRVLMTPRRAIGRQYQRMMKMLGVELEFTDGAMWATARAALRRNTGARGLRTLVERLLVDAMYEVPGLAEARSYLHWSPYDRVGVVSADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4T0</accession>
    <name>C1N4T0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_52669</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL43 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063050.1">
        <property type="nucleotide sequence ID" value="XM_003063004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4T0"/>
    <dbReference type="STRING" id="564608.C1N4T0"/>
    <dbReference type="GeneID" id="9688490"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52669"/>
    <dbReference type="eggNOG" id="KOG3445">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PNERVVC"/>
    <dbReference type="OrthoDB" id="88at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039927">
        <property type="entry name" value="Ribosomal_mL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="141" mass="15555" checksum="716DEB0C0493046F" modified="2009-05-26" version="1">MSIRGVWQLLRLNVSYCDVEGSSRALRAFVKDGKLAAFAARYPHVEVTTETRRGLHPHMRGEFRSGETKDVSLRRFDESEILFQLRYIVSEKGMKNAAKNSIRGDRKMTKTPSVQGKWRPGMWERGAGGGAAAAAAGGVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4T8</accession>
    <name>C1N4T8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52677</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062850.1">
        <property type="nucleotide sequence ID" value="XM_003062804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4T8"/>
    <dbReference type="GeneID" id="9688290"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52677"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="444"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="566"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="660"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="827"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="894"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="977"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1063"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="792"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="453"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="497"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="569"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="665"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="857"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="910"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1066"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1081"/>
            <end position="1123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1208" mass="128712" checksum="3F32F76209B66736" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4W6</accession>
    <name>C1N4W6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52705</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063067.1">
        <property type="nucleotide sequence ID" value="XM_003063021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4W6"/>
    <dbReference type="STRING" id="564608.C1N4W6"/>
    <dbReference type="GeneID" id="9688305"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52705"/>
    <dbReference type="eggNOG" id="KOG2148">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="27109at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048628">
        <property type="entry name" value="Sec3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092:SF14">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092">
        <property type="entry name" value="SEC3/SYNTAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20654">
        <property type="entry name" value="Sec3_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exocyst complex component Sec3 C-terminal" evidence="1">
        <location>
            <begin position="34"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="356" mass="40064" checksum="4BA4FA6D94770027" modified="2009-05-26" version="1">MATYVFDEDFGGDGVSSKRKNEVAARFRSVHIPEMQQLLEGVELDLNRIADWVVTSNPMRCISMLGEIGWTLERVGERQDDPLRDALISCQDKIQRHLFEYLERNFSKEEIKSQDGSGRTMAEAFVLAKSDVAVLNEVSALPSLIDRFEGFMSELTVDEKTTAKQIAIDNACAKLLDVVFRAINRAADLDSKKSIRLRLVNFCTLEEILQERSARVSKLDEFLKAALEARSKACHEYASVLAEKEFGAVLEIAYHMHVTLGSGGEVLELPFQPGCSREAVLRTVSSQSGHEKSLKVLHKRATKHLAALQPELFNSVWTFVLDFVTGWLVFLDSILRTPAYSYSMSPSPKKLRLLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4Z1</accession>
    <name>C1N4Z1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52730</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063079.1">
        <property type="nucleotide sequence ID" value="XM_003063033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4Z1"/>
    <dbReference type="GeneID" id="9688318"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52730"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="242" mass="22883" checksum="A07D797694D3E430" modified="2009-05-26" version="1">MGSLFGGLGMSGVTPTGLSFGGLISPGALQADLGASLEFPAASGGGGGGGGGGGLAAGILNNSLNAKHAVLKSSASAGGGTVGNGNGNGNGNGKKGDLRIDIPENTSKTIEVAAARGVGVGDASGASPSPGPLTSLLMRGPDGINLSGRGDGGGNEKATEAAAAAAAVRADAAKREEEKETTKLADGGGSFALPGLGGGDVDVPSPTALGGRDRAAGVKRARNASVSEPSPGTGKRSTRSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5E6</accession>
    <name>C1N5E6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53306</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063347.1">
        <property type="nucleotide sequence ID" value="XM_003063301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5E6"/>
    <dbReference type="GeneID" id="9688787"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53306"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="202" mass="20086" checksum="B643462ED00F3134" modified="2009-05-26" version="1">MALSRVRSTALTVSLDANVPNGGSPAQAVGRSVEAYCNALDRAEGENARVVLEWDRDAAARHAAAAAAAADRLAEATDGYGATDWRDAFLLGAGGGAAAATESLVDRATSAFVGGGGGGASSFDDDRWTKVVRLRAMNGCDGGSAAYLTLRVTPPVEGAGGGGDVVVARGPRPDGPPRGPKPDGPPRGPKPDDGPPPGALSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5N9</accession>
    <name>C1N5N9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_63726</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063191.1">
        <property type="nucleotide sequence ID" value="XM_003063145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5N9"/>
    <dbReference type="GeneID" id="9688631"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63726"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="198"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="997" mass="105692" checksum="9911C11BD6167224" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N651</accession>
    <name>C1N651_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_63867</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063474.1">
        <property type="nucleotide sequence ID" value="XM_003063428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N651"/>
    <dbReference type="GeneID" id="9688913"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63867"/>
    <dbReference type="OrthoDB" id="515385at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="138" mass="15194" checksum="AA199AF7D297C6F3" modified="2009-05-26" version="1">MTAHGVSGPRGVGSAMLDKNVEKLLSEPWGAAKVGVHYTKEVLGSLCEQFSRLEPQARRGALQGTLFMRKGQRSGLNDEVEDLVAVATDDKDQWASLIARALGGLKQRFDLQRLQQDVPAVSYSPDLERTLAREFRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6C4</accession>
    <name>C1N6C4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_53236</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063314.1">
        <property type="nucleotide sequence ID" value="XM_003063268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6C4"/>
    <dbReference type="GeneID" id="9688754"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53236"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="199" mass="21832" checksum="95B65E12CF6656F0" modified="2009-05-26" version="1">MDTISSLARELKTPPALPSFDVNESVASAVLSRVAHVQTRVSLSRVNKTWHRASKQAPSLPSSLDFSACPEAEYSTSSTSAKHVNAYSLAYLLRVEGFLDLPEGRLRDLVRSTLRGVPIFTSDRDGNVKLVDAMVDKMVDALVDLMKIAKDGGAVPVDSVHLDERVRKVGLSDLETRLFLEGFFSCTYDSDSCTYDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6M1</accession>
    <name>C1N6M1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit F</fullName>
            <shortName evidence="4">eIF3f</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">eIF-3-epsilon</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_45955</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit F family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063576.1">
        <property type="nucleotide sequence ID" value="XM_003063530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6M1"/>
    <dbReference type="STRING" id="564608.C1N6M1"/>
    <dbReference type="GeneID" id="9689017"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45955"/>
    <dbReference type="eggNOG" id="KOG2975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EYFVHFH"/>
    <dbReference type="OrthoDB" id="25498at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08064">
        <property type="entry name" value="MPN_eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03005">
        <property type="entry name" value="eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027531">
        <property type="entry name" value="eIF3f"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF6">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="6">
        <location>
            <begin position="16"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="170"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="334" mass="35003" checksum="E69D963E87658211" modified="2009-05-26" version="1">MVAFLPVAGAGKVAGARVHPVVVFNACDSFVRRAEAQDRVIGTLLGSVGVDGVVDVRNCYAVPHNEQNDTVYVDVEFHRAMIELHQKVNPSEKIVGWYSTGDGVVPTDALIHEFYSHECQNPVHVTLDVGFNDRAKLMRAWTGSSIAIGAQAKSAADAAGDKAAAAAAIAEKKETAPGEDGDDAAATGPGDDASASAAKPPAAIHFQEINLTNVFDEAERVGVARLCAPSSDASTSDDVSGADGLQKTVAKLSGMLDDAAKHVAAVCDGKAPADAEIGRHLSDALSAVPRLTKEQFEKLFGDSVADVLLTRYLANITKMQLMLAEKLQTTSLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6N2</accession>
    <name>C1N6N2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_5811</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant tobamovirus multiplication TOM1 protein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063762.1">
        <property type="nucleotide sequence ID" value="XM_003063716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6N2"/>
    <dbReference type="GeneID" id="9689023"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5811"/>
    <dbReference type="eggNOG" id="ENOG502QQMF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TAICCAC"/>
    <dbReference type="OrthoDB" id="19798at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040226">
        <property type="entry name" value="THH1/TOM1/TOM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009457">
        <property type="entry name" value="THH1/TOM1/TOM3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31142:SF3">
        <property type="entry name" value="THH1_TOM1_TOM3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31142">
        <property type="entry name" value="TOBAMOVIRUS MULTIPLICATION PROTEIN 1-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06454">
        <property type="entry name" value="THH1_TOM1-3_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="THH1/TOM1/TOM3" evidence="7">
        <location>
            <begin position="4"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="267" mass="29212" checksum="FD66C2745EB327B4" modified="2009-05-26" version="1" fragment="single">PRAQDAVFDALGGAYAIIALVALAQLARIHARVPEIGLTTQKVFHLLNASCALVRAVVFPLRRRLDAVRPRVIEHVLLDLPGLLFFSTYALLVLFWAEIYNQARSRPVAALKPTFVAVNVAAYVTQTALWIAAGYEPSHRGTFRVASLSVLASLSVLAAIGFATYGGRLFRMLRRVLSHTGPHTTARFPIESRGRSRKLREVGCVTVVCTFAFIARAGLVIASEIDPSRDGLDVLGHPARNCAYYASCEIIPSGLVLYVLRKLPPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7T4</accession>
    <name>C1N7T4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49066</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064147.1">
        <property type="nucleotide sequence ID" value="XM_003064101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7T4"/>
    <dbReference type="GeneID" id="9689406"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49066"/>
    <dbReference type="OrthoDB" id="539419at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014955">
        <property type="entry name" value="DUF1826"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08856">
        <property type="entry name" value="DUF1826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="230" mass="24218" checksum="D19A08A3F7F7B9D1" modified="2009-05-26" version="1">MSASAASASASAPRAHASRRTSSRSHRVAASTPSSAASRRRRERAASASSTSSDSTPSAPSALATGAAWDDAWGSIADDPDTRVAYVDDADRDSLRATLAASSLREALAGADVGETIVSGVLSTSAPIDVRGVLNLPRELLRDSDHYSAALPGLEAIERDVAAIVERYGVIARARSARVHVSLLRRTLCSKFHVDHVPLRVMVTYFGAGTEARSLHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N821</accession>
    <name>C1N821_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53914</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064006.1">
        <property type="nucleotide sequence ID" value="XM_003063960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N821"/>
    <dbReference type="GeneID" id="9689634"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53914"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="219" mass="22876" checksum="630A14731D7365C9" modified="2009-05-26" version="1">MPFMDALGEISDDSSSDDDDVAAAGRAVAASTTSMPSYEELTSYGMRGGGSLVDTPEYFAAGEPARAAADADAKADAARGAGGSKRAAAKEHGASDDDDDDASRPEFIKNAFGKWEVSRHKRAKREAQLAEEAAERRANRGPTWGEQRGELLRRQAATRNVASFDLTRAFGAAAREDDASSRAREALARGGATAGGGARGATSAPKRSRHDDAEVLVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N878</accession>
    <name>C1N878_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53981</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064221.1">
        <property type="nucleotide sequence ID" value="XM_003064175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N878"/>
    <dbReference type="GeneID" id="9689476"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53981"/>
    <dbReference type="OMA" id="MEHESWI"/>
    <dbReference type="OrthoDB" id="10409098at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="188" mass="20564" checksum="3D8E457231F7DCC0" modified="2009-05-26" version="1">MGAKKTLWIAWIINFVFGFLFCICAIVNASAVDKIRDHAHGLGDSSTEDLITAIVTTQAYGVVMCIIYGTFSLLVLLRKTTANSGAGVMYGVIIGSAVHMFFALAQVSALLMEHESWIKSLPAEYHWESDDKKTYEATYVMGFISCVLFFVLAVVKVFCISAVTKGDEPYDSFRDRYAREGGASANAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8B2</accession>
    <name>C1N8B2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_43287</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TPX2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064238.1">
        <property type="nucleotide sequence ID" value="XM_003064192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8B2"/>
    <dbReference type="STRING" id="564608.C1N8B2"/>
    <dbReference type="GeneID" id="9689493"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43287"/>
    <dbReference type="eggNOG" id="ENOG502QVQS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EFCAPHY"/>
    <dbReference type="OrthoDB" id="10689925at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027329">
        <property type="entry name" value="TPX2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06886">
        <property type="entry name" value="TPX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPX2 C-terminal" evidence="6">
        <location>
            <begin position="946"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="40"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="551"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="707"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="842"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="123"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="260"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="448"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="485"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="578"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="707"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="727"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1059" mass="111487" checksum="E7D66CD5184D7EAF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8E3</accession>
    <name>C1N8E3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_5563</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064069.1">
        <property type="nucleotide sequence ID" value="XM_003064023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8E3"/>
    <dbReference type="STRING" id="564608.C1N8E3"/>
    <dbReference type="GeneID" id="9689510"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5563"/>
    <dbReference type="eggNOG" id="KOG4308">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LQHCSCN"/>
    <dbReference type="OrthoDB" id="537968at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="268" mass="28045" checksum="B0A3350BDEED31D3" modified="2009-05-26" version="1" fragment="single">AESYVAACRAAGIVPQTAATRGLATDSDRCELRHRALGDAAVAAVAAALRNPLCVSLTRLDLRDNDVRDAGFVAIARGLTHNSVLTHLDLSDNPGPKLTGVEALRDALDPNCARRLKDSHCALTTLRLSNVGLDDVCGAKLGEVFADNSSVKSLDLSRNQLGPLTSAALASSVDQNQGVVELNVSRNNFGARCAARFAALVKVNATIRILDISHNGLEDEGTETIGLMLGGEVELKSLDLSATRMGERGAAAVAASLSRNESLESLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8I3</accession>
    <name>C1N8I3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54096</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064271.1">
        <property type="nucleotide sequence ID" value="XM_003064225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8I3"/>
    <dbReference type="GeneID" id="9689712"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54096"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="110" mass="11772" checksum="FCB686BA91541941" modified="2009-05-26" version="1">MASTPRALRRAAATATASSSSSSSSTRLRHHRLVRSSSSSTRRRRRRLVAVASSSSASDASFEDALRAAANRAIDAHVESGDRVGIGHGAMTSMALDRIHERLNDEVRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8Q8</accession>
    <name>C1N8Q8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54207</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064489.1">
        <property type="nucleotide sequence ID" value="XM_003064443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8Q8"/>
    <dbReference type="STRING" id="564608.C1N8Q8"/>
    <dbReference type="GeneID" id="9689759"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54207"/>
    <dbReference type="eggNOG" id="ENOG502QU37">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LSHPEDM"/>
    <dbReference type="OrthoDB" id="9970474at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.400.10">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039343">
        <property type="entry name" value="NDX1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35467">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35467:SF2">
        <property type="entry name" value="PROTEIN NEOXANTHIN-DEFICIENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="352" mass="37288" checksum="8E1D531C9494CC48" modified="2009-05-26" version="1">MGGGKGYGGKNRAPWRFQGRALYQLCLIKSSDARKHVPDDLKLVEAFGYTLGGVYLARYDDSPAGTFDELVALGGLVWNPPTSCAWAAKVFVNDHTARAHGVKTCGLPSAFASFKETTAEKTRGRDGGAGAGVDARGWWKNDRPTKKRWGRVPFLARREKRVAERVKLVDDAGGELCSLALPAAAPKLAGPRINMFLPSFSGRTPSCPDLLKYSLCLRANVRLSDWIRVGDVVAVEDDDAASDAEVSEKREEKAGTGEGGPGGFWAPSGERRFPPQLALASVSLSDVPATAAAATTIEEDEKGAASKSKSKTAAPGKSVAGDETLAAILGGKPLLCIAFDDMTMDVGHPVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8S7</accession>
    <name>C1N8S7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_54225</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064500.1">
        <property type="nucleotide sequence ID" value="XM_003064454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8S7"/>
    <dbReference type="STRING" id="564608.C1N8S7"/>
    <dbReference type="GeneID" id="9689767"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54225"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RKMNEGN"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000527">
        <property type="entry name" value="Calmodulin-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="132"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="169"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="205"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="237" mass="26524" checksum="280794EAE69D0379" modified="2009-05-26" version="1">MQARKIALRGRVRHDSHPFVAEPPHSRGAPAGSARGRSTFTALRDRRVSSHPAQHLARGAEEIERRTRGGRMSREGKKKYLTDEELSAEWPYLTRTQVKEFRDAFAIFDKDGGGSITTDELGDVMKSLGQKPSHAELDAMVREIDADGNGEIDFPEFLTMMLRKMNEGNPEKELMDVFMVFDKDGSGTISAEELRSAMRVIGEKLTDDEIEDAIKLADSSGDGEVDYDEFINFVLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8Z1</accession>
    <name>C1N8Z1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_54295</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064525.1">
        <property type="nucleotide sequence ID" value="XM_003064479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8Z1"/>
    <dbReference type="STRING" id="564608.C1N8Z1"/>
    <dbReference type="GeneID" id="9689966"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54295"/>
    <dbReference type="eggNOG" id="KOG1419">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498779at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001508">
        <property type="term" value="P:action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537:SF254">
        <property type="entry name" value="POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="VOLTAGE-GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ion transport" evidence="12">
        <location>
            <begin position="163"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH51430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="347" mass="37611" checksum="BA68703A62FF6023" modified="2009-05-26" version="1">MASLVAAAAAPRPRGVGATRGDAPRARVRARETTTTTATSGGTSSAAFSPLAPRRRVRRDRRVAAPPRAMYDDGDDDVGARSLDDYEFADDLGLRGPYRERRAFDAVEWHAMPLSRRCKDGLAVVDRSGVWIVGTTIGALIISVSETHLAARATTDGFARDRSFPFRAVFLFEFILRAWSEGFDLNYLRSPVALVDFAAVLPSLELFIGGGGGAAAAALRPLRLFRLLRLLRLVEAKNGGLSGDADRMTDKVTNVAVEFLCVFLLAGELFYDLEYEVNDNISDVGDALYWSFLTLTGIGQPFEAVTAAGRVATVGSILTALVVVPLQARSYLHWFPYDRVGAVHADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9E2</accession>
    <name>C1N9E2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_66651</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064605.1">
        <property type="nucleotide sequence ID" value="XM_003064559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9E2"/>
    <dbReference type="GeneID" id="9690046"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66651"/>
    <dbReference type="OMA" id="WEECECE"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="185"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="277" mass="30374" checksum="01E19BC7D30C1A0D" modified="2009-05-26" version="1">MAPAPENAEAIVARLNVILAESDLEETSIKDVHKALEKEFEVSIDQAFLREHVNGYLVANARATTSRSQKKKSFPPCSGSGACRVQCLCECYTIDEDEEDEVWDEVCTCGHRAHQGENWEDEPGLYCPDISCGDEACALVPCMACEEEAPSWLMECHGGFCSGNCAMEMDKACGPVTRVHEEGECPICLETRPLIALNACGHAFCVRCRIKDTRAKLARARETIYDAGDDGTVLPDVVSVCALCRRANPGKSFAALGELCHAQHEYRVEDKARPKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9M4</accession>
    <name>C1N9M4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_54542</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH50971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064637.1">
        <property type="nucleotide sequence ID" value="XM_003064591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9M4"/>
    <dbReference type="STRING" id="564608.C1N9M4"/>
    <dbReference type="GeneID" id="9690204"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54542"/>
    <dbReference type="OMA" id="WRINCDE"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="273"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="640"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="64"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="386"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="492"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH50971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="682" mass="71583" checksum="937ACCFDCBF3765D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Q0</accession>
    <name>C1N9Q0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_4389</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Responsible for microtubule translocation. May be important for the organization of phragmoplast-specific arrays of microtubules. Plays an essential role in stabilizing the mitotic spindle. Required during mitotic cytokinesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064773.1">
        <property type="nucleotide sequence ID" value="XM_003064727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Q0"/>
    <dbReference type="STRING" id="564608.C1N9Q0"/>
    <dbReference type="GeneID" id="9690214"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4389"/>
    <dbReference type="eggNOG" id="KOG0243">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANQERIY"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000019">
        <property type="entry name" value="Kinesin-like protein KIN-5D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047149">
        <property type="entry name" value="KIF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970:SF12">
        <property type="entry name" value="KINESIN FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 10 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="12">
        <location>
            <begin position="1"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH51107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="310" mass="33149" checksum="F6F7DEEE4FFECD77" modified="2009-05-26" version="1" fragment="single">VFGADASQSDVYDGAIAPIVEEVLEGFNCTIFAYGQTGTGKTHTMEGDLSAVGVDGGDADALPTDAGVIPRAMAHVFEYLKASGAEFEVKCTFLELYNEEITDLLSPESPAEGTLEAANAEKRRHNLLEDGKGGVSVKGLEEITARSPAEIFQHLARGSAKRRTAETLCNKQSSRSHSVFSVTIHTREHNAANGEDLIKQGKLNLVDLAGSENISRSGAKDSRAREAGEINKSLLTLGRVITALVDRLAHVPYRDSKLTRLLRDALGGKSKTCVVATISPASQNVDETVSTLEYARRAAAIKNKPEVNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA30</accession>
    <name>C1NA30_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Signal recognition particle 54 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_23850</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 15">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane. Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes. Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA. Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA. SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER. Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="12 15">Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.</text>
    </comment>
    <comment type="domain">
        <text evidence="15">The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064840.1">
        <property type="nucleotide sequence ID" value="XM_003064794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA30"/>
    <dbReference type="STRING" id="564608.C1NA30"/>
    <dbReference type="GeneID" id="9690281"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23850"/>
    <dbReference type="eggNOG" id="KOG0780">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MTIFVMD"/>
    <dbReference type="OrthoDB" id="10250817at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006616">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17875">
        <property type="entry name" value="SRP54_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000022">
        <property type="entry name" value="Signal recognition particle 54 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006325">
        <property type="entry name" value="SRP54_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01425">
        <property type="entry name" value="SRP54_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10 15" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="16">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU364034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH51174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="513" mass="55786" checksum="5DE09F195E9914A4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAA7</accession>
    <name>C1NAA7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_54822</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064872.1">
        <property type="nucleotide sequence ID" value="XM_003064826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAA7"/>
    <dbReference type="STRING" id="564608.C1NAA7"/>
    <dbReference type="GeneID" id="9690313"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54822"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF261">
        <property type="entry name" value="ZINC FINGER CONTAINING PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="62"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH50852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="228" mass="24854" checksum="012F2B48DE7DAE3A" modified="2009-05-26" version="1">MAAFFKPRLRRILLKWGFKRLADGIVPGLGGRISKLEAFMAKQKLPRLHGFTPEIDPSEITINKADVLGTGSYGTVYKASHISEEVAVKAMFESANDRLPAYAAKLLRNEAMLMCSLNHTNVVRILGAVTQKDTYLHDPDNTLDASDKARLATETATGMAYLHMREVDIIHGDIKAGNVLLVSDKSVRICDFGMAEAKNRSKTVTSAAAASNGRSSVALTVYANLLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGW0</accession>
    <name>C1MGW0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49958</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055388.1">
        <property type="nucleotide sequence ID" value="XM_003055342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGW0"/>
    <dbReference type="GeneID" id="9680239"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49958"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="321" mass="35027" checksum="907B09F99B28BCA3" modified="2009-05-26" version="1">MPKRGRRDVVTLSAELAAEIGCPTEMYEDELETRMETKSGGVLSALFAQVDLLRTRIFPLLSQTDLAIVAGLNRECRRAVWMYAPIDNPRFAVEDCVASVERLRWARANNCPWTEATMRHVVTRGSLAALQFAIQYGCPMYAEILVDAAMSAARARADDKEESKRRADVCRHLRAHVAALTLDVETRLDDAGRELAPLALEPSERWKDVRDMHPRQIRKKVGEIRDELRALRWRTSGGDGEGGAAEGGGGGGGGDADADPASRLARLERRLELFERVMKLKLRLACLPGGDGLVRLARRRLSGPSGDVDAAVGLGGGATGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH65</accession>
    <name>C1MH65_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_50066</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMGA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054898.1">
        <property type="nucleotide sequence ID" value="XM_003054852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH65"/>
    <dbReference type="STRING" id="564608.C1MH65"/>
    <dbReference type="GeneID" id="9680440"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50066"/>
    <dbReference type="eggNOG" id="ENOG502SGVU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VEEWTIC"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010557">
        <property type="term" value="P:positive regulation of macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000116">
        <property type="entry name" value="HMGA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23341:SF1">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN HMG-I_HMG-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23341">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEINS HMG-A AND C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02178">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00930">
        <property type="entry name" value="HIGHMOBLTYIY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="219"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="292"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="365"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="392"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="528"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="555"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="578"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="641"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="696"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="714"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH60150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="727" mass="73853" checksum="655532EABFE62D59" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHE6</accession>
    <name>C1MHE6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_49391</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055476.1">
        <property type="nucleotide sequence ID" value="XM_003055430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHE6"/>
    <dbReference type="STRING" id="564608.C1MHE6"/>
    <dbReference type="GeneID" id="9680592"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49391"/>
    <dbReference type="eggNOG" id="KOG1639">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ATMPIFN"/>
    <dbReference type="OrthoDB" id="540503at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF28">
        <property type="entry name" value="VERY-LONG-CHAIN ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="9">
        <location>
            <begin position="163"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="307" mass="34716" checksum="50925F0CC562EA13" modified="2009-05-26" version="1">MKLNIVKRNGKEMFAGGLDVPDDATTDDLKAVFAKAAKKHQTRQRFTLPIPAGADPKKVRGTPLDAGKSLSKDYGLKDGSVVVFKDLGPQVPYAVVFLAEYAGPMLCYLPFYFFRSAIYASTKKYPATAPMLQVQTLAMVFHTAHYLKRILETLFVHHFSHATMPIFNLYRNCAYYWGFAAIMSYFINHPAYTPVSETQMKVGFAVSALMQLGNLHCHVYQASLRKDGSKEYKEPKGGLFRFVTCANYCCEIYQWVGFNVATQSAMGWLFVACGAAQMMDWANAKHKRLKRLFPGFRRPFKLLPPFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MID5</accession>
    <name>C1MID5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_11956</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TAF15 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055110.1">
        <property type="nucleotide sequence ID" value="XM_003055064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MID5"/>
    <dbReference type="STRING" id="564608.C1MID5"/>
    <dbReference type="GeneID" id="9680350"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11956"/>
    <dbReference type="eggNOG" id="KOG1995">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NWARRTH"/>
    <dbReference type="OrthoDB" id="76445at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1060.10:FF:000008">
        <property type="entry name" value="TATA-binding protein-associated factor 2N isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1060.10:FF:000004">
        <property type="entry name" value="Zinc finger Ran-binding domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12999:SF17">
        <property type="entry name" value="ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12999">
        <property type="entry name" value="ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="11">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="11">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="79"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH60362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="134" mass="15079" checksum="6A714B529F5409DA" modified="2009-05-26" version="1" fragment="single">QQRDGDWPCPNPTCGNTNFAFRGRCNRCGEARPAGAGGDRGGRGRGGGDDRGPPGLFAPDDWSCQNCFNVNWARRNKCNECGHPKGGSQKERREGRGGGHREIDDEAERLETRRRRRENEEKEKYDDFGNLKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MID8</accession>
    <name>C1MID8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_9646</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055112.1">
        <property type="nucleotide sequence ID" value="XM_003055066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MID8"/>
    <dbReference type="GeneID" id="9680259"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9646"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF32">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="3"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="3"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="52" mass="6111" checksum="52459C7ADEFC9205" modified="2009-05-26" version="1" fragment="single">KKSKRSLGAYKIFYEEVRPKIVAAHPKFTIGEVREKVGEKWKKLSDAERKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIS5</accession>
    <name>C1MIS5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_46374</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055184.1">
        <property type="nucleotide sequence ID" value="XM_003055138.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MIS5"/>
    <dbReference type="GeneID" id="9680627"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46374"/>
    <dbReference type="eggNOG" id="KOG2247">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NDMLTHT"/>
    <dbReference type="OrthoDB" id="10250638at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057855">
        <property type="entry name" value="Beta-prop_WDR19_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056168">
        <property type="entry name" value="TPR_IF140/IFT172/WDR19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040379">
        <property type="entry name" value="WDR19/dyf-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039468">
        <property type="entry name" value="WDR19_WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14920">
        <property type="entry name" value="OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14920:SF0">
        <property type="entry name" value="WD REPEAT DOMAIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23389">
        <property type="entry name" value="Beta-prop_WDR19_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15911">
        <property type="entry name" value="Beta-prop_WDR19_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24762">
        <property type="entry name" value="TPR_IF140-IFT172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR19 first beta-propeller" evidence="8">
        <location>
            <begin position="1"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="WDR19 WD40 repeat" evidence="7">
        <location>
            <begin position="364"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="IF140/IFT172/WDR19 TPR" evidence="9">
        <location>
            <begin position="681"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF15911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1366" mass="148434" checksum="0295B47ED51D6DDB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIW9</accession>
    <name>C1MIW9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_61744</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055207.1">
        <property type="nucleotide sequence ID" value="XM_003055161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIW9"/>
    <dbReference type="GeneID" id="9680714"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61744"/>
    <dbReference type="OMA" id="FRECARI"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014977">
        <property type="entry name" value="WRC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08879">
        <property type="entry name" value="WRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51667">
        <property type="entry name" value="WRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRC" evidence="3">
        <location>
            <begin position="258"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="288"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="533" mass="55354" checksum="2F69F6C68A1ACC08" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIY4</accession>
    <name>C1MIY4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50742</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055742.1">
        <property type="nucleotide sequence ID" value="XM_003055696.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9680938"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50742"/>
    <dbReference type="OMA" id="VTEAHEN"/>
    <dbReference type="OrthoDB" id="10689618at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47357">
        <property type="entry name" value="COP1-INTERACTIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47357:SF1">
        <property type="entry name" value="SPINDLE POLE BODY COMPONENT 110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="443"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="587"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="787"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="918"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1151"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1221"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="406"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="630"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="152"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="370"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="443"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="518"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="787"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="927"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1180"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1221"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1269"/>
            <end position="1293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1293" mass="135364" checksum="DA26BC433BE2B93D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJA4</accession>
    <name>C1MJA4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_50868</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055278.1">
        <property type="nucleotide sequence ID" value="XM_003055232.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MJA4"/>
    <dbReference type="GeneID" id="9680470"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50868"/>
    <dbReference type="eggNOG" id="KOG1240">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ATNTCRI"/>
    <dbReference type="OrthoDB" id="242910at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071561">
        <property type="term" value="C:nucleus-vacuole junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13980">
        <property type="entry name" value="STKc_Vps15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045162">
        <property type="entry name" value="Vps15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583:SF0">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="72"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="9">
        <location>
            <begin position="693"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="1159"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="1609"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="398"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="466"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="889"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="956"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1259"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1474"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="956"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1477"/>
            <end position="1490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH60530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1643" mass="168137" checksum="19BB15590D94ADC4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJD0</accession>
    <name>C1MJD0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_13068</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055292.1">
        <property type="nucleotide sequence ID" value="XM_003055246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJD0"/>
    <dbReference type="GeneID" id="9680493"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13068"/>
    <dbReference type="eggNOG" id="KOG1285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RVEYTRF"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF138">
        <property type="entry name" value="CAROTENOID OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="595"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="604" mass="66403" checksum="287427B0B49C2ECC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJD4</accession>
    <name>C1MJD4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_50898</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055813.1">
        <property type="nucleotide sequence ID" value="XM_003055767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJD4"/>
    <dbReference type="GeneID" id="9680358"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50898"/>
    <dbReference type="eggNOG" id="ENOG502RZWK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DCRDFTN"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36342">
        <property type="entry name" value="PTB DOMAIN ENGULFMENT ADAPTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36342:SF1">
        <property type="entry name" value="PTB DOMAIN ENGULFMENT ADAPTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH61065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="147" mass="15581" checksum="5C4E2912CCDE093F" modified="2009-05-26" version="1">MEPLADALEDAYPARLEHTMLLVRHRGETACVAYDFLPIEPTSPATAATLLSGGAVRGDRRVRALSRVPSRRCWRVGDTTPGLGGGGAAGVDAVARAFQSTYDASLRLRENGCREHTAAMALAMTGITLDLDALLIEGDANRSDDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJN6</accession>
    <name>C1MJN6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_38336</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">JanA and janB regulate somatic sex differentiation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the janus family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056243.1">
        <property type="nucleotide sequence ID" value="XM_003056197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJN6"/>
    <dbReference type="STRING" id="564608.C1MJN6"/>
    <dbReference type="GeneID" id="9681419"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38336"/>
    <dbReference type="OMA" id="QVQLTHP"/>
    <dbReference type="OrthoDB" id="10249612at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101006">
        <property type="term" value="F:protein histidine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007548">
        <property type="term" value="P:sex differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.20.20">
        <property type="entry name" value="Janus/Ocnus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007702">
        <property type="entry name" value="Janus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038596">
        <property type="entry name" value="Janus_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12258:SF5">
        <property type="entry name" value="BCDNA.GH02250-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12258">
        <property type="entry name" value="JANUS-A/JANUS-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05005">
        <property type="entry name" value="Ocnus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143724">
        <property type="entry name" value="PHP14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0221">Differentiation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0726">Sexual differentiation</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR607702-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR607702-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="172" mass="18550" checksum="FD10AA9D0E7C231B" modified="2009-05-26" version="1">MPPSDEPARFCDETGEALNAAARAVVAEAIGADRARDDVSNDAAAKLGPVLRSVPIVKLERGTHKYVQVQLTHPDEPGTAILVVRSVDVRRCPYHADVYRALVDELGSDARTRGVIGRVIGGGRIRRDAATVSVYGYSKTFGRTRGCNERTAELIRANVDGLASVEWSDDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK26</accession>
    <name>C1MK26_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64182</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055918.1">
        <property type="nucleotide sequence ID" value="XM_003055872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK26"/>
    <dbReference type="GeneID" id="9681917"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64182"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="138" mass="15807" checksum="FB6798FF1298E16A" modified="2009-05-26" version="1">MSTRISYYAETAPRGSRLRRRRRREEKRIRKRARLAHHTSPRVIQHTAFVPPAHSSSTRPPSRYVTPQRSTREMSIRAAAPNMGPFTRLVCTNFRTLHTKYAPGPLLPTTDGRSAGGADLVRVHVHVPVRVHVVWTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK75</accession>
    <name>C1MK75_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Acyl-coenzyme A oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_31340</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056334.1">
        <property type="nucleotide sequence ID" value="XM_003056288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK75"/>
    <dbReference type="STRING" id="564608.C1MK75"/>
    <dbReference type="GeneID" id="9681672"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31340"/>
    <dbReference type="eggNOG" id="KOG0136">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AHAQYMV"/>
    <dbReference type="OrthoDB" id="538336at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000015">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000005">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000013">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000003">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029320">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
        <property type="entry name" value="Acyl-CoA_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF250">
        <property type="entry name" value="PEROXISOMAL ACYL-COENZYME A OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14749">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000168">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-coenzyme A oxidase N-terminal" evidence="15">
        <location>
            <begin position="55"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="14">
        <location>
            <begin position="174"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="16">
        <location>
            <begin position="313"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-terminal" evidence="13">
        <location>
            <begin position="545"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="469"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH59710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="728" mass="80113" checksum="71850FCE4F011EE3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKD3</accession>
    <name>C1MKD3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer dynein arm docking complex 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ODA-DC3</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_49419</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055975.1">
        <property type="nucleotide sequence ID" value="XM_003055929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKD3"/>
    <dbReference type="STRING" id="564608.C1MKD3"/>
    <dbReference type="GeneID" id="9681689"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49419"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WEFDENM"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="13"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="175" mass="20261" checksum="3920D6E3D7FF7787" modified="2009-05-26" version="1">MAQAARERFAKKNEAEDLLRAFRRLDTRGDGKIDADELSSVFRILGHTAKKTEIEDMIWEVDDDCDMCVNWPEFQTMYNRCRQDKTGYEPRRLFNVVEFLMNDKDDSGTVSIEEAMQILYLRFGKGLLDSHLEDMFGTSDANSTSDLTLTEFLNSLHLSQAKHLRSTAKSHQQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKU0</accession>
    <name>C1MKU0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Component of splicing factor SF3B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49441</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHF5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056053.1">
        <property type="nucleotide sequence ID" value="XM_003056007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKU0"/>
    <dbReference type="STRING" id="564608.C1MKU0"/>
    <dbReference type="GeneID" id="9681980"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49441"/>
    <dbReference type="eggNOG" id="KOG1705">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AYYCWEC"/>
    <dbReference type="OrthoDB" id="10248186at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005345">
        <property type="entry name" value="PHF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13120">
        <property type="entry name" value="PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03660">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016468">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="110" mass="12381" checksum="77BA83C44817CB14" modified="2009-05-26" version="1">MAKHHPDLIMCRKLPGISIGRLCEKCDGRCVVCDSFVRPATLVRVCDECDYGTQHGRCVICGNPGVADAYYCKECTILEKDRDGCPKIVNIGSAKTDLFYERKKYGFKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKU3</accession>
    <name>C1MKU3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_55462</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056055.1">
        <property type="nucleotide sequence ID" value="XM_003056009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKU3"/>
    <dbReference type="STRING" id="564608.C1MKU3"/>
    <dbReference type="GeneID" id="9681732"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55462"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NAWFQGW"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061513">
        <property type="term" value="F:glucose 6-phosphate:phosphate antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051337">
        <property type="entry name" value="OPA_Antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43826">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43826:SF3">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="501"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="540"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="567"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="138"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="601" mass="65377" checksum="540FFB6DBF48BE73" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKY1</accession>
    <name>C1MKY1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64699</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056464.1">
        <property type="nucleotide sequence ID" value="XM_003056418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKY1"/>
    <dbReference type="GeneID" id="9681541"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64699"/>
    <dbReference type="OrthoDB" id="10630938at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="430" mass="46941" checksum="1960EE8AFDABC240" modified="2009-05-26" version="1">MGANFDFHPGRDPNQGDHSKELHAEFSPSRGTAEDTRRHGSVSNFGAGGQRHYRRRMVGQASVSTETTLKFTEGGLGPHRGAILYGHHDIVGSISPEQPNQRRFPRMMQQGQTFVGMALPPADPAPEPPPADPYPWADHFLDHSGKMSNRGKDDCEGENIYFGGQKRHSDRDPSDTSHLFTNPDSPSPEQPSKEQRWKRGMAIGRFSPMLRPDVALPTGVVPALAETSDSVNGRDDNTGFGRRSVGVRVLPEGIYAGTKSDPRNAEMIGKKMSYPQMTTNTFESVGMTPKALGVIDDRVQSVKFQPTHYAGGMPVPGKRGLVGPRKKAYPNMTKNTFDSVGITPKALGVPDDVDCIRPSMPNNMAGASTDFLACHRVAKKPGYFSHAAKSQNTFESVGRAMVLLDESGSPLGEPKHEKYIENNSRSGRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLC1</accession>
    <name>C1MLC1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_55662</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056142.1">
        <property type="nucleotide sequence ID" value="XM_003056096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLC1"/>
    <dbReference type="GeneID" id="9681780"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55662"/>
    <dbReference type="OrthoDB" id="512750at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_bL35-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_bL35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36400">
        <property type="entry name" value="RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36400:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="L35p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002911980" evidence="4">
        <location>
            <begin position="21"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="186" mass="21319" checksum="5AFDA5CED2BFFEC3" modified="2009-05-26" version="1">MSSLLFTSSRVFLLPFLSLTAPITNPGVACPRKIERFIAPLKERMKTKSMCNVDDKFESRPLELLNILRSRSNVPRLVLSSPRLKSVVDTNLRNTANSFFAREIHSVSNIHLQMCSFRGMKTKIKPYSSWKARFRATATGKYARKQKGKRHKASSKTLRQKMLLRATKLVHNSLVQPMKKLGFNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLP3</accession>
    <name>C1MLP3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55787</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056603.1">
        <property type="nucleotide sequence ID" value="XM_003056557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLP3"/>
    <dbReference type="GeneID" id="9681811"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55787"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="19751" checksum="F3A488297FF64353" modified="2009-05-26" version="1">MELLAIIAENEYIRIENEKLKALLSGTRCPHLTQKGLPCKNNGLCALSIAKGSLDWNEIIDAAVYGNVQRGTKGSGFRMIWSHKMAKGVEQLAYLPVFVYTHGPLSTILKIDRKPDLEILKMSVVRTDAPQTHVIQPPSTTIGEGKFTREQTKDEIHNEELRDLSRVRTFYYFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLQ8</accession>
    <name>C1MLQ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pilus-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HPR</name>
        <name evidence="1" type="ORF">MICPUCDRAFT_70764</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056206.1">
        <property type="nucleotide sequence ID" value="XM_003056160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLQ8"/>
    <dbReference type="GeneID" id="9681858"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70764"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="48" mass="5523" checksum="F6B5993B957A764D" modified="2009-05-26" version="1">MFVQSGDYGGITGLLGTGHMAELFEFVTCLDHRRTERMTEWRATIKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMC5</accession>
    <name>C1MMC5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56478</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056907.1">
        <property type="nucleotide sequence ID" value="XM_003056861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMC5"/>
    <dbReference type="GeneID" id="9682818"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56478"/>
    <dbReference type="OMA" id="QWHIVAM"/>
    <dbReference type="OrthoDB" id="10057036at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23534:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23534">
        <property type="entry name" value="MFS PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="479" mass="48602" checksum="B99598181604896A" modified="2009-05-26" version="1">MATAASATARGGSVTTTRDAANLARVASRSVPRDWHDVVFASLAQAAATSGFGIIVSTLVVATIARTGVRGLGTASLALEFATRSVVSLPLARLATTRGRRVVVAVSGALGVAGALLATVDFFLSTARVPYFLGIALLGVANCASQQLRFVAAAAVVPASQPRALSVGIAGGTIAAFVGPELAKASRTSLEKEYAGSFLAMAGCYAALVMFTLPLREEGPAAAKSASGVSVEGDEEDEPPPTYEEDEPPLPPTPLKQLFRSSFSARKGLACVAVSWAAMFVVMSAAPVAMIKAGHSFDDAATALQYHMILMFLPGLLGTGDCVRVLGPDVVAIAGCALYVACGFFTYAAEGGGGDASSRDGRVSLWVFQAILIALGLAWNLLFVSGSGMMTPAQCSPTLTRAECVRAQGVAETASFGAVAVVAACAGVALDEIGWAALCACLMPLGAGCGTYVLIERARARARGGVGKGGGDLDASARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMF7</accession>
    <name>C1MMF7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carnosine N-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_3417</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnosine N-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056920.1">
        <property type="nucleotide sequence ID" value="XM_003056874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMF7"/>
    <dbReference type="GeneID" id="9682837"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3417"/>
    <dbReference type="eggNOG" id="KOG2798">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GSMSMCA"/>
    <dbReference type="OrthoDB" id="978at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030735">
        <property type="term" value="F:carnosine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF6">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="354" mass="39808" checksum="565045939C23968C" modified="2009-05-26" version="1" fragment="single">DEELERAAFLKIVRAMRDYASDAAREVHRWERNYERLPENHRALLSHHVAKHDDAYRCVKRNDDFFKEMLSSFTGDDVPPHLRVPPPGEMAHEPVAPSDAVKVLYVLKNLARDWSAEAADERLQSHGPILAELERRLKAVPGRPPPRVMVPGAGLGRLVLECARRGWESEGNEYSYYMLLTSSFILNHATKAEQFTIHPWMHTNNNHLSDANQLRGVKVPDVPACDAGVPPGCMGMCAGDFVEVYGAAENAGRWDAVATCFFIDTAHNVIEYLEIISRCLKPGAVWVNFGPLLYHWADADGYLSADEMSVEMSLEDVERVADAVGLDVVKKEMRESKYTGDKMSMCQTVYECAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMN1</accession>
    <name>C1MMN1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56593</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057435.1">
        <property type="nucleotide sequence ID" value="XM_003057389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMN1"/>
    <dbReference type="GeneID" id="9682396"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56593"/>
    <dbReference type="eggNOG" id="ENOG502R8PP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TERFLWN"/>
    <dbReference type="OrthoDB" id="527994at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051291">
        <property type="entry name" value="CIMAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010736">
        <property type="entry name" value="SHIPPO-rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21580:SF28">
        <property type="entry name" value="BOREALIN N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21580">
        <property type="entry name" value="SHIPPO-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07004">
        <property type="entry name" value="SHIPPO-rpt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="702" mass="72701" checksum="EB7410A3AA15D463" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN00</accession>
    <name>C1MN00_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46860</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057014.1">
        <property type="nucleotide sequence ID" value="XM_003056968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN00"/>
    <dbReference type="GeneID" id="9682453"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46860"/>
    <dbReference type="OMA" id="WRMISES"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="851"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="922"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="978"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="851"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="922"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1043" mass="106769" checksum="09FB5AD9576569A9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN10</accession>
    <name>C1MN10_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="2 6">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_32627</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>9-ribosyl-trans-zeatin 5'-phosphate + H2O = trans-zeatin + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:48564"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16522"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:87947"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O = N(6)-dimethylallyladenine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:48560"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17660"/>
            <dbReference type="ChEBI" id="CHEBI:57526"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the LOG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="2 6"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057500.1">
        <property type="nucleotide sequence ID" value="XM_003057454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN10"/>
    <dbReference type="STRING" id="564608.C1MN10"/>
    <dbReference type="GeneID" id="9682460"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32627"/>
    <dbReference type="eggNOG" id="ENOG502QTZZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HQKPIGL"/>
    <dbReference type="OrthoDB" id="414463at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102682">
        <property type="term" value="F:cytokinin riboside 5'-monophosphate phosphoribohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00730">
        <property type="entry name" value="Rossman fold protein, TIGR00730 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223:SF70">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="224" mass="22923" checksum="F30E843AC232C510" modified="2009-05-26" version="1">MTTSPRGEAPAAAAAAAPAAAHFASVCVYCGSSAGDRPEFADAARSLGAELASRGSRLVYGGGSVGLMGAVSTTAHANGGRVLGVIPVALEPVEVSGGSVGEVMVVEDMHERKAAMAAASDAFIAMPGGFGTLEELLEMITWQQLGYHAKPVGVLNVAGYFDLFLKFLDESTARGFIRREARAIVVVGDTPAELLDKLETYAPPRSLIESLAKENGGGGGDAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNM3</accession>
    <name>C1MNM3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55957</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057133.1">
        <property type="nucleotide sequence ID" value="XM_003057087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNM3"/>
    <dbReference type="GeneID" id="9682572"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55957"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="67" mass="6910" checksum="9B0C39AE731BAC51" modified="2009-05-26" version="1">MPGTEPGAPPRYVLPGPAYSPAEAAEARFREKIQAERAAEKAATQKRYDALEAAEAAAKAAAEAAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPC9</accession>
    <name>C1MPC9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56231</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057261.1">
        <property type="nucleotide sequence ID" value="XM_003057215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPC9"/>
    <dbReference type="GeneID" id="9682240"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56231"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1220"/>
            <end position="1244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1244" mass="133213" checksum="9D864CCB05F2EAAE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPP6</accession>
    <name>C1MPP6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_16552</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057989.1">
        <property type="nucleotide sequence ID" value="XM_003057943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPP6"/>
    <dbReference type="STRING" id="564608.C1MPP6"/>
    <dbReference type="GeneID" id="9683014"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16552"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KLWPTDQ"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="10"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="4">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="304" mass="33678" checksum="F7B0D16735B625D7" modified="2009-05-26" version="1" fragment="single">LRTGATIPLIGLGTWKSEPGKVRAAVTHALKRGYAHVDCASVYENEGEVGDALRGVFDSTTLLREDVFITSKLWNSDHAADRVEPACKKSMDLLKVRYLDLYLVHWPVTGNRGAAVTPSIEETWRAMEALVDEGLVRAIGVSNFSVEKMEAISKYARHPISVCQVECHPYWRQTELVKYCEANDIHVTAYSPLGSPDSAAMFKRDAPALMSDPVVIAAAERAGKNVGQTLVRWALQTRPNCSVLPKSTDPARIEGNLDVLDWSLDEEDARALSELPTRRRMVDGSFWLSPLGPYKTLEDLWDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPX2</accession>
    <name>C1MPX2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57073</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058023.1">
        <property type="nucleotide sequence ID" value="XM_003057977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPX2"/>
    <dbReference type="GeneID" id="9683024"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57073"/>
    <dbReference type="eggNOG" id="ENOG502RXU7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SRMEMSE"/>
    <dbReference type="OrthoDB" id="75833at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36357">
        <property type="entry name" value="OS03G0148300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36357:SF1">
        <property type="entry name" value="OS03G0148300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912031" evidence="2">
        <location>
            <begin position="42"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="237" mass="26735" checksum="BDCB2B7AF4842946" modified="2009-05-26" version="1">MARRAPRRRGGGATSSLSSLLFLLLLLLLSLLLATPTLVRAKPRPKIPDNLDNVWDDEEDDDFKSWGEEKFGRQPVDGADDAPLFDANGQMDPKSLAKLQERSRAGPQLTFVKLHPDPVAGPRSIDEVNVIGERWATLMRSGGVSDRVYGIDTDTMLVQLKDGRYMDELREFLWMQEEVREFEWNSKRWLKGNDEPEPPTPKPKPDAAKKEKKKKKKKKKSEGRDGGGDGGEKRVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ77</accession>
    <name>C1MQ77_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_57188</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058079.1">
        <property type="nucleotide sequence ID" value="XM_003058033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ77"/>
    <dbReference type="STRING" id="564608.C1MQ77"/>
    <dbReference type="GeneID" id="9683517"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57188"/>
    <dbReference type="eggNOG" id="ENOG502QSC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GRFCCRD"/>
    <dbReference type="OrthoDB" id="1737200at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001293">
        <property type="entry name" value="Znf_TRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131:SF161">
        <property type="entry name" value="F26K24.24 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131">
        <property type="entry name" value="TNF RECEPTOR ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02176">
        <property type="entry name" value="zf-TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50145">
        <property type="entry name" value="ZF_TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TRAF-type" evidence="6">
        <location>
            <begin position="218"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TRAF-type" evidence="4">
        <location>
            <begin position="218"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="411" mass="44136" checksum="82B11AED6DF5F576" modified="2009-05-26" version="1">MGEESPPAAADSPPREKEDSASFKRAWAGARDAATSCRCAHLCLASHANVSRALVDAIAKAAVFQTAGKPFGDANDLVAKLATDLVAKLMKFADDAENGKSGLAPNLADLAAWINEWVTGKRSFFGEFGAMWSKEKQTEAVERVRQDVARGECWPAADRERVSRELLLRYDRGKVAHCEEAFATEDELFEHKKKCAFRPTQCPNEGCMEVHGANVAAAHDAQCPHKIVKCPNACDSTNVTRRALKMHVDLECPRRPVTCPFAPFGCASHVYAGTLRAHMKEHAHDHVADLAKRVGRMSDAAEKTEAKVAEMAVALADVGPNLGKVGNLSKELFDTTAKATIVEKGLLDLEKLVVSMGKALANLEVQVKQQRKDIGIVMTAVDRVAKETAGNSAAIAKLASPDAAAGSNGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQA2</accession>
    <name>C1MQA2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_16660</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057722.1">
        <property type="nucleotide sequence ID" value="XM_003057676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQA2"/>
    <dbReference type="STRING" id="564608.C1MQA2"/>
    <dbReference type="GeneID" id="9683530"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16660"/>
    <dbReference type="eggNOG" id="KOG2093">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TRCKPDG"/>
    <dbReference type="OrthoDB" id="427711at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017125">
        <property type="term" value="F:deoxycytidyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053848">
        <property type="entry name" value="IMS_HHH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21999">
        <property type="entry name" value="IMS_HHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UmuC" evidence="3">
        <location>
            <begin position="46"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="345" mass="36656" checksum="AFBD0F87998EB010" modified="2009-05-26" version="1" fragment="single">MGTFFRASRLHYIGSWRARYETFLDDETTTPPPLPPPAAKNGERLVMHVDMDCFFAAVAALGRPELRDLPIAVSWSSGGQGELSSCNYAARAFSCKAGMRVGHAKSLCPRLVVMPYEFEKYSEIALEVYRVLHAITPHVMGVSVDEAYVDVTQRANAGEDARAIAEDVRRKIFAKTGCAASVGSGPNRLIARLATKRAKPDGAFHVSLAAAPAFMSSLPAAELPGVGRGALKKLAAAGVGGGGGVGGELELTCADVVSAPLTSLQRALGPKAGVALRDAARGVDTRAWEARPPRRSVGAQVTWGVRFVEASEAVAFVTKLATEVATRMKRVRVKGKSLTLKILRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQT9</accession>
    <name>C1MQT9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_67467</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058186.1">
        <property type="nucleotide sequence ID" value="XM_003058140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQT9"/>
    <dbReference type="GeneID" id="9683253"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67467"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="19099" checksum="EC00E2410F3A2BF3" modified="2009-05-26" version="1">MSRRRAPPAATSDGRERRPVLLFRASAAKHDSHPPMRRGHDLIISPTPPPMPMNDSDPPLPPFPRLAPACRSRIIREVPRFLFDLTACGILSFASSTESTRRMPPFSFLCTFASTPPCLDLSFVPALGSSISSRSTLLLLELKSCCIFRSFSVGKYLLRVTRLSSGCRRVLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR41</accession>
    <name>C1MR41_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_33167</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058237.1">
        <property type="nucleotide sequence ID" value="XM_003058191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR41"/>
    <dbReference type="STRING" id="564608.C1MR41"/>
    <dbReference type="GeneID" id="9683304"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33167"/>
    <dbReference type="eggNOG" id="KOG3358">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KPQHGTR"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23294">
        <property type="entry name" value="beta-trefoil_MIR_AtSDF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809:SF2">
        <property type="entry name" value="GH21273P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809">
        <property type="entry name" value="STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910612" evidence="4">
        <location>
            <begin position="25"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="5">
        <location>
            <begin position="40"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="5">
        <location>
            <begin position="103"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="5">
        <location>
            <begin position="166"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="237"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="275" mass="30415" checksum="CAB97620FB123F69" modified="2009-05-26" version="1">MRRSALFLTAVACVLALFATPAFAWDDDDDDPANVDAADYEGVTCGSTIKLQHSGTKARLHSHDIAYGSGSGQQSVTGFPETTDANSYWQVLHAHGAEPCRFGTEIANGAIVRLLHINTKKWLHSHLHKSPITGNQEVSAYGTRGDGDTPEDSNSDDNWKIELSAGETVWKKDKKMRLIHVSTGVILHSHDQKFGRPIAGQFEVCGAKSKNNNNLWFATEGVYIPKPKPSKHAHAFTIRKLPYDPRKDDDDGEELKNEAAKEDLKNEKKKKKVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSA2</accession>
    <name>C1MSA2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">E2F/DP family winged-helix DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_58408</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the E2F/DP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058647.1">
        <property type="nucleotide sequence ID" value="XM_003058601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSA2"/>
    <dbReference type="STRING" id="564608.C1MSA2"/>
    <dbReference type="GeneID" id="9684454"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58408"/>
    <dbReference type="eggNOG" id="KOG2578">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KYTWHGI"/>
    <dbReference type="OrthoDB" id="5318at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000073">
        <property type="entry name" value="E2F transcription factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000295">
        <property type="entry name" value="E2F transcription factor-like E2FE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015633">
        <property type="entry name" value="E2F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003316">
        <property type="entry name" value="E2F_WHTH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12081">
        <property type="entry name" value="TRANSCRIPTION FACTOR E2F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12081:SF7">
        <property type="entry name" value="TRANSCRIPTION FACTOR EFL-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02319">
        <property type="entry name" value="WHD_E2F_TDP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01372">
        <property type="entry name" value="E2F_TDP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="E2F/DP family winged-helix DNA-binding" evidence="11">
        <location>
            <begin position="156"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="E2F/DP family winged-helix DNA-binding" evidence="11">
        <location>
            <begin position="360"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="115"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="244"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="477"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="543"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="293"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="810" mass="80829" checksum="1A2C597F7F190827" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSP9</accession>
    <name>C1MSP9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exon junction complex protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PYM1</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_67922</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058715.1">
        <property type="nucleotide sequence ID" value="XM_003058669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSP9"/>
    <dbReference type="STRING" id="564608.C1MSP9"/>
    <dbReference type="GeneID" id="9684154"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67922"/>
    <dbReference type="eggNOG" id="KOG4325">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MERRCTP"/>
    <dbReference type="OrthoDB" id="21625at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903259">
        <property type="term" value="P:exon-exon junction complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039333">
        <property type="entry name" value="PYM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015362">
        <property type="entry name" value="WIBG_mago-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036348">
        <property type="entry name" value="WIBG_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959:SF0">
        <property type="entry name" value="PARTNER OF Y14 AND MAGO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959">
        <property type="entry name" value="PYM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09282">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01273">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101931">
        <property type="entry name" value="Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WIBG Mago-binding" evidence="2">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="229" mass="23846" checksum="B3A952D5705A9E2D" modified="2009-05-26" version="1">MTPTTTPDEETRRKPPPAGFKEELPERVIAASRRPDGSMRKEIRVRAGYVNQDEVRRYVVRGARGRGDAAGGGGGGGGGAGGVPGAFAEEAKSDAARKNARKKAAKKEKEKEKEKDARAKSGEGGDEEKKTKTTPPAAAAAAAAAPEDEDPARALSKRARAAKKKVRACEDLAARARDGADLDDDQRAKLEKMAAFAAEAEALERQLAALSTGGGRDATTGAGATLARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSU6</accession>
    <name>C1MSU6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_47229</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058740.1">
        <property type="nucleotide sequence ID" value="XM_003058694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSU6"/>
    <dbReference type="STRING" id="564608.C1MSU6"/>
    <dbReference type="GeneID" id="9683830"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47229"/>
    <dbReference type="eggNOG" id="ENOG502QQ1I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PVNIRAN"/>
    <dbReference type="OrthoDB" id="498745at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37204">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37204:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910466" evidence="1">
        <location>
            <begin position="32"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="360" mass="37804" checksum="7C137B0C962E4338" modified="2009-05-26" version="1">MAGPRRSRLAARRRTIARCCACVVLALAALAARPTARGVGDARERARRRASVDPSLLEEWSRSRLPPKCSRALSGSVDAASGSWALSHVASRSKLYAAMDAELTERGLTAFDDAGGARTQGSGVDDLFAFDRVTGLARAKLTRLDVAVRAIVLPLPRRSRAAFRMRRATRAVVAAAGYHDGRDAWLQDPDAYHFSMFHASHHLAPTPASAAEVEAEMRAVARVVRGACAMTATIERVVATPSGSVVALWNLAGGSEPSAFRDALRAALPNAPAAQIVSDEHIMHTTLARLLRPPPGAGGDAAAATAAAAAIARQLTERLCGVEVTLPIAWFVQERDKLALALGGAHDATPTTFDACGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSZ8</accession>
    <name>C1MSZ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_57886</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058408.1">
        <property type="nucleotide sequence ID" value="XM_003058362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSZ8"/>
    <dbReference type="STRING" id="564608.C1MSZ8"/>
    <dbReference type="GeneID" id="9684209"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57886"/>
    <dbReference type="eggNOG" id="KOG0442">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THILDIM"/>
    <dbReference type="OrthoDB" id="361020at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20078">
        <property type="entry name" value="XPF_nuclease_XPF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000002">
        <property type="entry name" value="DNA repair endonuclease XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047520">
        <property type="entry name" value="XPF_nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150:SF0">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="11">
        <location>
            <begin position="904"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="392"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="504"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="582"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="704"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="424"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="511"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="582"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="594"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="606"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="647"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="708"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="724"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH56863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1140" mass="121926" checksum="E8DC88514DF01A67" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTC7</accession>
    <name>C1MTC7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58022</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058842.1">
        <property type="nucleotide sequence ID" value="XM_003058796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTC7"/>
    <dbReference type="GeneID" id="9683904"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58022"/>
    <dbReference type="OrthoDB" id="513166at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910650" evidence="1">
        <location>
            <begin position="30"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="92" mass="9382" checksum="8562F77DF3BF0A75" modified="2009-05-26" version="1">MSRRSPSAFLAALLAAMVCLLLAATPAAALAPRGRDASTSITAPAPGGECAAKTTQRSCKPPCVWCAAAAVPSECVDPRDAKKLPPAIFDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU11</accession>
    <name>C1MU11_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_58629</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS54 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059415.1">
        <property type="nucleotide sequence ID" value="XM_003059369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU11"/>
    <dbReference type="STRING" id="564608.C1MU11"/>
    <dbReference type="GeneID" id="9684855"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58629"/>
    <dbReference type="eggNOG" id="KOG2115">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10259024at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039745">
        <property type="entry name" value="Vps54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019515">
        <property type="entry name" value="VPS54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10475">
        <property type="entry name" value="Vps54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 N-terminal" evidence="8">
        <location>
            <begin position="157"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="541" mass="55544" checksum="20F97C6A14C3C571" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU57</accession>
    <name>C1MU57_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58675</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059140.1">
        <property type="nucleotide sequence ID" value="XM_003059094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU57"/>
    <dbReference type="GeneID" id="9684506"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58675"/>
    <dbReference type="OMA" id="NATEHAC"/>
    <dbReference type="OrthoDB" id="10632589at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="475" mass="54589" checksum="FD344029077DE1DB" modified="2009-05-26" version="1">MDLERGERRPRREGERRHRDDGRGERRHRDDGRGERRHRDRDNPRERRERGDPRAGHGGEARRGPPRPGRRRPPHLIRRHKKPKPPGLHVMGVKVTFWRVSLLAFLLAFCVVAGAWLAPSYERYKNRPSTVRQFCEVLDSNADTGCVAVRLLYESDCDNPYAYNSAAEGGGTTKAQDKAACEAMMKRLCVYSDDQKAASDAWPPDPNAISPDLRAAYVARYPNATEHACWYPPGEMERGMTFTPPREYWDDFFNALMTMIPILFGLLLSFWCVVRRKRTHPELEDEEMLSGLFDEVVSHKDGMRALAEEQSRAVRSLQAKLDREQEKRIDFVLEVEKEKKERLMSEDNIKHAVNANLRSMESKLAAEMAARLAQALGKKGKRAAKKFEKERLLNSGDGGTRPDSAASIYEEHERDYARRRAALADDIEAQRSAFHKRLADRKARPEPGERREGRERGGDRGERRSKSRGPRRDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUM8</accession>
    <name>C1MUM8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LHCA</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_49623</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059523.1">
        <property type="nucleotide sequence ID" value="XM_003059477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUM8"/>
    <dbReference type="SMR" id="C1MUM8"/>
    <dbReference type="STRING" id="564608.C1MUM8"/>
    <dbReference type="GeneID" id="9684963"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49623"/>
    <dbReference type="eggNOG" id="ENOG502S0WM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ELMNARW"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="235" mass="24996" checksum="6640E444F9A1603F" modified="2009-05-26" version="1">MAALTTTSLTAVSAVRGARSAFAGSRAAFVAAPAMKVSSRASLTVKAQRELWIKDSTVAPAHLDGTLPGDFGFDPLGLGADPQRLKYYQEAELMNARWAMMAVAGITATEVLGIGPAWYDVGAADFDFPPLALLAIQFPVMGILELKRIRGWLDTGKSGVVDQFPWDPMGMNSDGMAVKEIKNGRLAMIAFVGIVVQAIVYREGPVAALKDHVTDPFGCNMASNIMSIPEHLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUT8</accession>
    <name>C1MUT8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_47564</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059556.1">
        <property type="nucleotide sequence ID" value="XM_003059510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUT8"/>
    <dbReference type="GeneID" id="9684996"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47564"/>
    <dbReference type="eggNOG" id="ENOG502QRQG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FTRHHCD"/>
    <dbReference type="OrthoDB" id="496771at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21385:SF0">
        <property type="entry name" value="RE51073P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21385">
        <property type="entry name" value="ZINC FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912155" evidence="3">
        <location>
            <begin position="25"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="324" mass="36047" checksum="DC393E5FC4755461" modified="2009-05-26" version="1">MTRVAAMCVIALAAFASCIAGVVGDSHASAPACSRERSRRARAVLDDYFYPVVDRHAGSFEVPPACPFQRSKDMYLEQEKHKERVRRTQWKSLYSEKVFRTEWHVDKHMDNRHADKIPPGADVCLADYCAVLRCDEHHAHRNPDDPSRSGSRGAPSRSKGGGGGGAGARRARRERCDESKLAGARHFCETLMHACFPSDDDAESDGDRGGGARGHGAAGRLRAYFTRHHCDQLTCDAVAGMFQIMDGHHLNREGRRGAFVFVVVFCVVLAAYYVVAWRHAVGGRARGDLRRATARKGAWVNVDRITRSWPLCVVLGKRRKRKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVR4</accession>
    <name>C1MVR4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59475</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060085.1">
        <property type="nucleotide sequence ID" value="XM_003060039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVR4"/>
    <dbReference type="GeneID" id="9685523"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59475"/>
    <dbReference type="eggNOG" id="ENOG502QQTP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LVIQWIF"/>
    <dbReference type="OrthoDB" id="202063at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="292" mass="32689" checksum="903ED9B70332B138" modified="2009-05-26" version="1">MDGPAPPEDATRPDPSPSPRMDIQPRREASPPPRDRAASGRGGGGIVGVVSRWKPLETPRFTSCVLLYLLGIFVAFYATPPVTITDAMQTKYFDMMEAADAIDLEPRTAAETALYHATMDVHRARNSQWFCWSSAPCRARVNKAKARQRAKLRDAEVYRKRRDAKVREAKRTLGLWSALGVDEAKALFRDCYERGKVFATRNTYYDTFWLIIGGRSDDSLAELLIRWGFTVLSNFTVGMASAVISFAWRLPALIRTFAAGTWSGLVFFGVATIRRVLSVQTFFTHPPLGFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW73</accession>
    <name>C1MW73_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40678</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060167.1">
        <property type="nucleotide sequence ID" value="XM_003060121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW73"/>
    <dbReference type="GeneID" id="9685312"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40678"/>
    <dbReference type="eggNOG" id="ENOG502SBMZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FNQGGEF"/>
    <dbReference type="OrthoDB" id="2018221at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35732">
        <property type="entry name" value="OS10G0545100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35732:SF1">
        <property type="entry name" value="OS10G0545100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="594"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="651"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="716" mass="78340" checksum="0B053EA1D8F4ECCC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWD0</accession>
    <name>C1MWD0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_71066</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060192.1">
        <property type="nucleotide sequence ID" value="XM_003060146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWD0"/>
    <dbReference type="GeneID" id="9685344"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_71066"/>
    <dbReference type="eggNOG" id="ENOG502S2UE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IKERYRA"/>
    <dbReference type="OrthoDB" id="204494at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="526" mass="56049" checksum="AE54E9C0F340A6B5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWG5</accession>
    <name>C1MWG5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59758</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059920.1">
        <property type="nucleotide sequence ID" value="XM_003059874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWG5"/>
    <dbReference type="GeneID" id="9685650"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59758"/>
    <dbReference type="OrthoDB" id="426386at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="88" mass="9151" checksum="B552E9D2540B7353" modified="2009-05-26" version="1">MNAGLDAAPGWTLFAFVLIDMGSALCLYALFAAAKVPVDADFALAYAVSKSIRAPRLALGAFCFLRRAGSRATASAIGTGPHTTPFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWU4</accession>
    <name>C1MWU4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_5008</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059690.1">
        <property type="nucleotide sequence ID" value="XM_003059644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWU4"/>
    <dbReference type="STRING" id="564608.C1MWU4"/>
    <dbReference type="GeneID" id="9685422"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5008"/>
    <dbReference type="eggNOG" id="KOG4581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CKSYQED"/>
    <dbReference type="OrthoDB" id="5263at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042371">
        <property type="term" value="P:vitamin K biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13962">
        <property type="entry name" value="PT_UbiA_UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026046">
        <property type="entry name" value="UBIAD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13929">
        <property type="entry name" value="1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13929:SF0">
        <property type="entry name" value="UBIA PRENYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="318" mass="33355" checksum="41375588F9B45878" modified="2009-05-26" version="1" fragment="single">RATLWWRALKIPMYSVCVAPLIVAASLCHHWYGCVNASQFGLFALGGCLVIAWLNLSNDAWDAATGVDDDKEMDGGGKPESIVRLMGGDVHAVNKVSLLAVGCLLSGIGALVMASTVDVAGVSSNVLSMLGVAVLCGQAYQGPPFRMSYKGLGEPLCFAAFGPLATGAFYLALAAGTGGSVWVNAPLTPVLSQGGVFGAAIMVGLTTTCILFTSHFHQEAGDRAAGKMSPVVKLGLERAIRTLRCALAIGMGWIGALPRMGALAVFLCSPLAIAIARYATEHEATPERLFKTKYLAVRWHAASSLAMAIGIWLDPWFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWU9</accession>
    <name>C1MWU9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_9357</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059692.1">
        <property type="nucleotide sequence ID" value="XM_003059646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWU9"/>
    <dbReference type="STRING" id="564608.C1MWU9"/>
    <dbReference type="GeneID" id="9685425"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9357"/>
    <dbReference type="eggNOG" id="ENOG502SWHK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="515836at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21553">
        <property type="entry name" value="VEFS-box_EMF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019135">
        <property type="entry name" value="Polycomb_protein_VEFS-Box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF0">
        <property type="entry name" value="POLYCOMB PROTEIN SUZ12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09733">
        <property type="entry name" value="VEFS-Box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Polycomb protein VEFS-Box" evidence="7">
        <location>
            <begin position="2"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH55644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="92" mass="11037" checksum="5D29BB527D2833E8" modified="2009-05-26" version="1" fragment="single">VEDSDDEEDLDEWTREDLRQLSDFEDIDHREKLFMHEWNVFVHRFKPYADRDVPAALAAFAKYRGDALRADPALRRMFVLHLVNQWDFGVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX96</accession>
    <name>C1MX96_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 18">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="12">IMP dehydrogenase</shortName>
            <shortName evidence="12">IMPD</shortName>
            <shortName evidence="12">IMPDH</shortName>
            <ecNumber evidence="12 18">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MICPUCDRAFT_27930</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12 18">
            <text>IMP + NAD(+) + H2O = XMP + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 18">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12 17">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="12 18"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060654.1">
        <property type="nucleotide sequence ID" value="XM_003060608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX96"/>
    <dbReference type="STRING" id="564608.C1MX96"/>
    <dbReference type="GeneID" id="9685796"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27930"/>
    <dbReference type="eggNOG" id="KOG2550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MGYCGAK"/>
    <dbReference type="OrthoDB" id="416622at2759"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04601">
        <property type="entry name" value="CBS_pair_IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000086">
        <property type="entry name" value="IMP dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911:SF111">
        <property type="entry name" value="INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01240">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0129">CBS domain</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 12 18" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 12 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12 14" id="KW-0520">NAD</keyword>
    <keyword evidence="7 12 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 12 15" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 12 18" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="19">
        <location>
            <begin position="111"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="19">
        <location>
            <begin position="174"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="12 13">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12 13">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12 14">
        <location>
            <begin position="273"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 14">
        <location>
            <begin position="323"/>
            <end position="325"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="363"/>
            <end position="365"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="386"/>
            <end position="387"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="410"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00056556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEH55423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="511" mass="53938" checksum="A66F9363BE020B18" modified="2009-05-26" version="1">MSKRKSVTMDDVDGFSAAQLFGQGVCYTYDDVIFHPGHINFAATEVDLTTKLTKNITIRTPIVSSPMDTVTEADMAIAMASVGGAGFLHYNMTQEEQIANLKAVKAHRLGYVTRPEVVSPDATLEFLDELATRRGFTSACVTDTGAVGGKLLGLVTSRDAELVADRSTKVVDVMTSASDLLVGSATDGVAALEELLLKSKKGKMPVVNAETGELVGLITRASIKQKKLLPPPGAPSLDKKGRLLCGAAIGTRPADRDRAVALAAEGVDALILDSSQGDSTYQIEMVKFLKKTIPEVDVIAGNIVTQNQARRLLDAGADALRVGMGSGSICTTQEVCAVGRGQATAVYKVANLAAQYDVPIIADGGIQNSGHVTKALTLGASTAMCGSMFAGTTEAPGEYFYVDGVRVKKYRGMGSLDAMKKGSDTRYLSESGHLKVAQGVSGTVKDKGSVCKMVPYLIHGVKQGFQDMGAKSHAHATELRNAGDMRVETRTGAAQAEGGVHDMHSYKKVLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXL2</accession>
    <name>C1MXL2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Ca2+:Cation antiporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MICPUCDRAFT_18857</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060710.1">
        <property type="nucleotide sequence ID" value="XM_003060664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXL2"/>
    <dbReference type="GeneID" id="9685856"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18857"/>
    <dbReference type="eggNOG" id="KOG1307">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YPFTFLI"/>
    <dbReference type="OrthoDB" id="2127281at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008273">
        <property type="term" value="F:calcium, potassium:sodium antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000009">
        <property type="entry name" value="sodium/potassium/calcium exchanger 5 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00367">
        <property type="entry name" value="calcium/sodium antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846:SF8">
        <property type="entry name" value="INNER MEMBRANE PROTEIN YRBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="SODIUM/POTASSIUM/CALCIUM EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="16" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="10" id="KW-0769">Symport</keyword>
    <keyword evidence="7 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="19">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="19">
        <location>
            <begin position="195"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEH55479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="357" mass="38291" checksum="7A69AF7019203C62" modified="2009-05-26" version="1" fragment="single">LSEDVAGATFMAAGSSAPELFTSTMSLVSSNATNELGVATIVGSAVFNILIIIACTIIFSGGDALELDWKPVTRDCVFYACSIAFLLAIMSDGKVWWYEGVVSVGLYLVYVYFMTKNARIMAWVDAKNNEEEEDHNLTGDGALNDDDDDDDDDRSPFAPPSSLAAYPLWLLSLPWYAAFRVTCPDCSKPDGEKYYLASFFVSVFWISAISYGMVDAAAAVGCILGIPEVVMGTLVLAAGTSIPDALSSVSVAQSGQGDMAVANAVGSNVFDILLGLGLPWIVFLPSRGGFEVVSTKQLWPSIFILAGVLALYYSTVAGNKFKLVKSMGYAYLATYAAFVVYSLVAVWYLDVYDVHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXM8</accession>
    <name>C1MXM8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MICPUCDRAFT_60218</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060719.1">
        <property type="nucleotide sequence ID" value="XM_003060673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXM8"/>
    <dbReference type="STRING" id="564608.C1MXM8"/>
    <dbReference type="GeneID" id="9686156"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60218"/>
    <dbReference type="eggNOG" id="KOG1778">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MIKSQHN"/>
    <dbReference type="OrthoDB" id="899at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15614">
        <property type="entry name" value="PHD_HAC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15802">
        <property type="entry name" value="RING_CBP-p300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1020.10">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031162">
        <property type="entry name" value="CBP_P300_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010303">
        <property type="entry name" value="RING_CBP-p300"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000197">
        <property type="entry name" value="Znf_TAZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808">
        <property type="entry name" value="CBP/P300-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808:SF1">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02135">
        <property type="entry name" value="zf-TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00551">
        <property type="entry name" value="ZnF_TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57933">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51727">
        <property type="entry name" value="CBP_P300_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50134">
        <property type="entry name" value="ZF_TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 21" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TAZ-type" evidence="18">
        <location>
            <begin position="324"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="17">
        <location>
            <begin position="565"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="CBP/p300-type HAT" evidence="20">
        <location>
            <begin position="658"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="19">
        <location>
            <begin position="1101"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="domain" description="TAZ-type" evidence="18">
        <location>
            <begin position="1161"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="295"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="924"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EEH55488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1272" mass="141568" checksum="827508D617ED4876" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXS7</accession>
    <name>C1MXS7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_60272</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060745.1">
        <property type="nucleotide sequence ID" value="XM_003060699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXS7"/>
    <dbReference type="GeneID" id="9685886"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60272"/>
    <dbReference type="eggNOG" id="KOG3200">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KSPKTKW"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032862">
        <property type="entry name" value="ALKBH6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="151"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="300" mass="32612" checksum="EAEC032BCFEC0864" modified="2009-05-26" version="1">MNGRRTPIRVSRSIFSEIFARSHSVLSQSTTREYAYGLTEAVLVSELGSRNSPRSGLARGMDAHALARAPVPGVYLLYDFDTAAEESYLLSRVDNEPKTRWTTVSDRRVLQFGGRPTATKHGMIAEKIPEWLLDAFYTLVPIRPHPRVREDLNHVLVNAYEPGRGIMPHEDGPLYDPAVAIVSLGASATMRFTPRRRDDADADAADGGGGRASDAAAAFGVWLPPRSLLVFTGAAYTEYLHGIEDVAEDVVDESVANRDAAAKAVGGGGGADGPLVIPRERARVSLTCRRVLKTRKILAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYA6</accession>
    <name>C1MYA6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_59837</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060543.1">
        <property type="nucleotide sequence ID" value="XM_003060497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYA6"/>
    <dbReference type="STRING" id="564608.C1MYA6"/>
    <dbReference type="GeneID" id="9685694"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59837"/>
    <dbReference type="eggNOG" id="KOG1764">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="449052at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF128">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="312"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="454"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="592" mass="64338" checksum="ADF036C2EA293D6C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYM0</accession>
    <name>C1MYM0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68925</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060591.1">
        <property type="nucleotide sequence ID" value="XM_003060545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYM0"/>
    <dbReference type="GeneID" id="9685682"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68925"/>
    <dbReference type="OMA" id="YEVQQHI"/>
    <dbReference type="OrthoDB" id="10431038at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="132" mass="14747" checksum="40F796E0335A0FF4" modified="2009-05-26" version="1">MSTPTTETPVDVSFHLDAGLANEDPENYLVVHELMGRGQLLNAYEAKLQHQHGVEFGVGILNKGKAQKREKRPPTQIEIMAAVEREKQEKKAARKAAKEAKVEARKAAEEFAANGGNKKLSKKERRKLENDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ80</accession>
    <name>C1MZ80_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="2">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_20099</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GARS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="2"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061168.1">
        <property type="nucleotide sequence ID" value="XM_003061122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ80"/>
    <dbReference type="STRING" id="564608.C1MZ80"/>
    <dbReference type="GeneID" id="9686351"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20099"/>
    <dbReference type="eggNOG" id="KOG0237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KATVCKY"/>
    <dbReference type="OrthoDB" id="2018833at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000006">
        <property type="entry name" value="Phosphoribosylamine--glycine ligase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000006">
        <property type="entry name" value="phosphoribosylamine--glycine ligase, chloroplastic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.600.10:FF:000001">
        <property type="entry name" value="Trifunctional purine biosynthetic protein adenosine-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="entry name" value="Phosphoribosylglycinamide synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PHOSPHORIBOSYLAMINE--GLYCINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLAMINE--GLYCINE LIGASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01209">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="13">
        <location>
            <begin position="171"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH54818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="494" mass="51231" checksum="28A2286A96703A2F" modified="2009-05-26" version="1">MPQTLRAPVTAAARARAPDATLRRSRVTPLRANARAAKRRVLVIFAAASSAPIVAAASGDAKTNVLVVGGGGREHSLCWRLRQSPTCGNLFCTPGNAGIASEDGVEVVRVNESDHAAVVKFCEEKGVGLVVVGPEAPLVDGLADSLAAAKIPCFGPSKSAARLEGSKGFLKDLLKKYDIPTAKYERFTDPEKAKAYIKSEGAPIVVKTDGLAAGKGVIVAMDLDTALAAVDDMMLNAAFGAAGDEIVVEEFLTGEEASFFAVVGGGVAVPLVGAQDHKRVGEGDTGLNTGGMGAYSPAPVLTPEMEAKVMKTIVQPTVDGMAAEGCPFTGVIFAGLMIEGDDVKLLEHNVRFGDPECQCLMVRMKSDLVELLSRAATGALDGSEKLEWSDDVAMNVVVAANGYPGSYAKGEVIEGLDDADALPGVKVFHAGTASNADGEIVSAGGRVLGVVAVGDDIAEAAKRAYDGVDAIVWPGGFVRRDIGWRAIARDEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZJ2</accession>
    <name>C1MZJ2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_60750</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060964.1">
        <property type="nucleotide sequence ID" value="XM_003060918.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MZJ2"/>
    <dbReference type="GeneID" id="9686403"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60750"/>
    <dbReference type="eggNOG" id="KOG1932">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RWIEGCG"/>
    <dbReference type="OrthoDB" id="308861at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057345">
        <property type="entry name" value="Ig-like_TAF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037813">
        <property type="entry name" value="TAF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15137">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15137:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25316">
        <property type="entry name" value="TAF2_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 2 Ig-like" evidence="8">
        <location>
            <begin position="791"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="187"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="385"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="579"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1405"/>
            <end position="1697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="595"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1442"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1462"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1521"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1540"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1573"/>
            <end position="1601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1654"/>
            <end position="1664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1673"/>
            <end position="1689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1697" mass="176386" checksum="E3060FA1D1206E0E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2024-11-27" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZQ5</accession>
    <name>C1MZQ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_60815</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Asterix family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060994.1">
        <property type="nucleotide sequence ID" value="XM_003060948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZQ5"/>
    <dbReference type="GeneID" id="9686700"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60815"/>
    <dbReference type="OMA" id="FCAWAGA"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045048">
        <property type="term" value="P:protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005351">
        <property type="entry name" value="ASTER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13193">
        <property type="entry name" value="CGI-140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13193:SF0">
        <property type="entry name" value="PAT COMPLEX SUBUNIT ASTERIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03669">
        <property type="entry name" value="ASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="113" mass="12222" checksum="08ABE1B1C47374BF" modified="2009-05-26" version="1">MVLAKGVKLEEDPRDPEGIVRFKRPTLTEAELAQDGYSLFALMLSLLGVMLGGRKIFCWTGALLAVASVVNRRAHDADTKQIWTAALFGVGGLFIMILNGKQGEKARAGGFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N029</accession>
    <name>C1N029_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48167</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061324.1">
        <property type="nucleotide sequence ID" value="XM_003061278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N029"/>
    <dbReference type="GeneID" id="9686763"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48167"/>
    <dbReference type="OrthoDB" id="580209at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="716" mass="78837" checksum="CE9BCE4D19688A52" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N069</accession>
    <name>C1N069_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_60992</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061342.1">
        <property type="nucleotide sequence ID" value="XM_003061296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N069"/>
    <dbReference type="STRING" id="564608.C1N069"/>
    <dbReference type="GeneID" id="9686516"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60992"/>
    <dbReference type="eggNOG" id="KOG1558">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DCTSHDD"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF209">
        <property type="entry name" value="ZIP ZINC TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910575" evidence="6">
        <location>
            <begin position="28"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="444" mass="47076" checksum="99E1F68568606F34" modified="2009-05-26" version="1">MKTTVTMKLLVSLLLALLCATAPVVRASGDPFEELTELYVTDTTSTTLNSDEVQLMFDDLQSLIDTGHPANEHAHSEAKSTLTVAEIITEHGSSNALTEDQFKAACPEILVCAVEDTCTFDTTETTGSMDYVGLKMGLAVVIFVEALIGGLLPLFFIKNLAKADSIMSLLNAFSGGVFITAGLTHILPHVVESQADVDDLYNEYPLAYALVVIGFIMIFLVERVIFHAHGHSAEEEEGHSHGHSHSKSDEKYMVGLVDGDSVKKATKEGFKTSLVILLAISLHAILAGVSMGIQSESENVYTVFVAIASHKAPAAFSIGSKFIRNGMDAKTVVSLIVVFSLVTPVGIIIGFLVGSTSAVARLVLEGLAAGTFIYIGATEVTADEFEMTARACSKLHSGAAAGAATVHTHKTHEVPGMAARLVAFGAYAFGCLVILLANLAPHYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N091</accession>
    <name>C1N091_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50932</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH53985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061355.1">
        <property type="nucleotide sequence ID" value="XM_003061309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N091"/>
    <dbReference type="STRING" id="564608.C1N091"/>
    <dbReference type="GeneID" id="9687032"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50932"/>
    <dbReference type="eggNOG" id="ENOG502QQWW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="532384at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46873">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46873:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="3">
        <location>
            <begin position="231"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="403" mass="42550" checksum="859313F8CDDA53CE" modified="2009-05-26" version="1">MHPHARGPRHSRRLRTSREARGPAVCLLCSLVTAITMVLILARMTYTRAREHHEVAAMFDAGRESAARSANIARPAGGGLGGVNKNPNLDARGRPRDPAFLMCGAADDMWNVEYGGDVVATPDVSAAAAPGNIIRTPTECCIRCAKTKGCNLYVFGGEGRRGTPEGMKCWLKHTHDPKHPVVRAEGEDVGWTSGALMKDYDAGASPGAGAGGGGGDRTGSGGDVVVPGAVALDTPAGRIEIELMPGWHAASVAHVARLARERGSCENSCHLYRAEPGFLLQGTLKSFSVRPNEETKRGPKVMERGEIGWAGEGAGPDFFVYLGDRPATHWGTGHTVWGKVTDEWSLRVADAIVNGPSHTPGGEGTMRFLKDFMYFDVVESERPPPPSSSSSSSSSSVGGGGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0A5</accession>
    <name>C1N0A5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_50947</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061599.1">
        <property type="nucleotide sequence ID" value="XM_003061553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0A5"/>
    <dbReference type="STRING" id="564608.C1N0A5"/>
    <dbReference type="GeneID" id="9687038"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50947"/>
    <dbReference type="eggNOG" id="KOG2207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WVGPKSH"/>
    <dbReference type="OrthoDB" id="497581at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="entry name" value="YbaK/aminoacyl-tRNA synthetase-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052408">
        <property type="entry name" value="Exonuclease_MUT-7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002782">
        <property type="entry name" value="Mut7-C_RNAse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765">
        <property type="entry name" value="3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765:SF2">
        <property type="entry name" value="EXONUCLEASE MUT-7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01927">
        <property type="entry name" value="Mut7-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="YbaK/ProRS associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="578"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="YbaK/aminoacyl-tRNA synthetase-associated" evidence="4">
        <location>
            <begin position="774"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="domain" description="Mut7-C RNAse" evidence="3">
        <location>
            <begin position="949"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="711"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1118"/>
            <end position="1174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1174" mass="125022" checksum="9B1D8149B3541F34" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0E5</accession>
    <name>C1N0E5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_41525</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061623.1">
        <property type="nucleotide sequence ID" value="XM_003061577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0E5"/>
    <dbReference type="STRING" id="564608.C1N0E5"/>
    <dbReference type="GeneID" id="9687062"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41525"/>
    <dbReference type="eggNOG" id="KOG4573">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70161at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034497">
        <property type="term" value="P:protein localization to phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040182">
        <property type="entry name" value="ATG13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018731">
        <property type="entry name" value="Atg13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13430:SF4">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10033">
        <property type="entry name" value="ATG13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autophagy-related protein 13 N-terminal" evidence="2">
        <location>
            <begin position="13"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="227" mass="25018" checksum="E34D481BF0CE371B" modified="2009-05-26" version="1">MATADRATQITREWFAKCANVILCSRLADDDPHAAQTPTRARDRWFNLDMDEHATHASSIKPWRRGGAASVHASTPLVIDVFVDARMRDVDVADDATAAEAVSRTLVERWVLSHDARCRGDGEEEEEVVEEEEEECTSSSSDVAVTYKRAVIMVRSLLALTRALPANRLHRARVRGGARDDASYRLSCEVRDVGTLGTNPGTDEGRHPGADAWRTYEFAPVDAAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0L8</accession>
    <name>C1N0L8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">G2-like myb-family transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_62878</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061410.1">
        <property type="nucleotide sequence ID" value="XM_003061364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0L8"/>
    <dbReference type="STRING" id="564608.C1N0L8"/>
    <dbReference type="GeneID" id="9687104"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62878"/>
    <dbReference type="eggNOG" id="ENOG502RIEW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000007">
        <property type="entry name" value="Two-component response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044841">
        <property type="entry name" value="LUX/BOA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31442:SF29">
        <property type="entry name" value="HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31442">
        <property type="entry name" value="HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="57"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="344" mass="34180" checksum="20EF057144BBA152" modified="2009-05-26" version="1">MGTSHDDGDAGADADADADADADADADADAAETETATTVTGEKRVSDGEKEATSGRATKKRRLVWTPELHVRFMSAVNHLGITNAVPKTILQLMNVEGMTRENVASHLQKYRLYLKRLAGVPPNAPLPPDVMRRAHPYHFPAAAAFPPPTPTIEQMHAGLPPSMPSMQSMPSMQSMPATMPNMSALMQMPAYNSAMGAMGAAMGGMGGMYASWPPAPPACAGSGAATMGLPGASASDPYGAAAAQSFMNYVANYRPGGGVPGKDASSSAAAAAAAAAMASHGWGFPGHAGGAWSAGAGAAATSAAMTSAAMTSAAMTSAAAASAIADGGCSAPAAGGPDAGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0Q7</accession>
    <name>C1N0Q7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ceramide glucosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_51114</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.80" evidence="5"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061432.1">
        <property type="nucleotide sequence ID" value="XM_003061386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0Q7"/>
    <dbReference type="STRING" id="564608.C1N0Q7"/>
    <dbReference type="GeneID" id="9687121"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51114"/>
    <dbReference type="eggNOG" id="KOG2547">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SFAFICD"/>
    <dbReference type="OrthoDB" id="1483400at2759"/>
    <dbReference type="UniPathway" id="UPA00222"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008120">
        <property type="term" value="F:ceramide glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006679">
        <property type="term" value="P:glucosylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726:SF0">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912303" description="ceramide glucosyltransferase" evidence="13">
        <location>
            <begin position="21"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="413"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="24"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH54062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="506" mass="54796" checksum="D1461B14BFDDE010" modified="2009-05-26" version="1">MAQAIAVYVAFVVAWRWAAARRARGRRGIEARGTARSAYCVPSDDEEEEEEEEEEDGDDDDDDDDDGGVRRRRRTRGAARSRSRTRRSAAPPPPPPPVAIVLPVKGVKPDSEDNWRAQLSSSYAGDREYVFVVESADDPAAAAATRLAKEFGRDRAGRAGRVRVRVLEAGSSTRSSQKIHSMLKGARAVCGGGGDDDDDDAGAKYVLFLDDDIRTHANTIGSLVSSMETLGEDAFLVNGYPFDIPEESAASSAAFVDYLTMVYHLVLIVAFSQGAVAKNVWGGCMLLRASDVRQNTHGWVTRYEDGGYSDDLILASLCDEHARVIGCPFDALFPQRMGGGGGGRKSKKTFARWWNYLRRQLFVMDTYSNAHNRRVNHAMLLVLSYLSLAVTTGMACALTELASWGSARSEVDVRFPSLAAAVVVAFACAVRSARAMYAAMGDLAEALGDADANALVKKINWAKVAAAFACAYALVPIAAAITATRATVVWEGVAYEKRRGKVTRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0S3</accession>
    <name>C1N0S3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Diacylglycerol kinase</fullName>
            <shortName evidence="9">DAG kinase</shortName>
            <ecNumber evidence="9">2.7.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_51131</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.107"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eukaryotic diacylglycerol kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.107" evidence="9"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061689.1">
        <property type="nucleotide sequence ID" value="XM_003061643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0S3"/>
    <dbReference type="STRING" id="564608.C1N0S3"/>
    <dbReference type="GeneID" id="9686881"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51131"/>
    <dbReference type="eggNOG" id="KOG1169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="242257at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007200">
        <property type="term" value="P:phospholipase C-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037607">
        <property type="entry name" value="DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000756">
        <property type="entry name" value="Diacylglycerol_kin_accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255">
        <property type="entry name" value="DIACYLGLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255:SF54">
        <property type="entry name" value="DIACYLGLYCEROL KINASE THETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00609">
        <property type="entry name" value="DAGK_acc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00045">
        <property type="entry name" value="DAGKa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DAGKc" evidence="11">
        <location>
            <begin position="30"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="236"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="304"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="669"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="274"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="309"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="361"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="444"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="681"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH54319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="690" mass="72472" checksum="3811032E45FA1A52" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N153</accession>
    <name>C1N153_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51266</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061509.1">
        <property type="nucleotide sequence ID" value="XM_003061463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N153"/>
    <dbReference type="GeneID" id="9686949"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51266"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="146" mass="16034" checksum="8F9883CD5AC277F8" modified="2009-05-26" version="1">MTPATITEQNFPAVHLSCIFGAAHFFYAWVFFVLSTSSRCSALRLKIIRGYACGLSVFYLANLKYPAAGRAHDSMWEMPLPVLYSLSAAALFGSCGFENVFARRSQRNRKKPSAGEPTPPRVDAVGRQGEAKVNERRDAATRGPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1B8</accession>
    <name>C1N1B8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_51339</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061785.1">
        <property type="nucleotide sequence ID" value="XM_003061739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1B8"/>
    <dbReference type="STRING" id="564608.C1N1B8"/>
    <dbReference type="GeneID" id="9687224"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51339"/>
    <dbReference type="eggNOG" id="KOG0756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="APICAVQ"/>
    <dbReference type="OrthoDB" id="44467at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071913">
        <property type="term" value="F:citrate secondary active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006843">
        <property type="term" value="P:mitochondrial citrate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF4">
        <property type="entry name" value="TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="89"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="187"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH54415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="285" mass="28670" checksum="E3EEF76B1395400F" modified="2009-05-26" version="1">MASSEPLGPWTKAGIGALAGLVEVSCQQPLHALKNCVQDGRRFPLANPIAWYRGWLACVCVSAPTTATQFGGGAAFAALASSSQTPRADAGAVGAASAFAAGAASGAALNPFDLGAIQQQKHGGSLPGTARRLIREHGVGVLTRGGMATMAREGTYVLGFMWATPLIARRLAERGDAADGDVGASAVAVGDRLAASVVAGVAASVLTQPFDVVKTRMQANLGEGGGGDGGYRRVAAAVFRERGAAGLWLGLLPRALRVVGATFIVSSVDANASAMVATRRATAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1F7</accession>
    <name>C1N1F7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aspartate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Aspartyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_44735</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061556.1">
        <property type="nucleotide sequence ID" value="XM_003061510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1F7"/>
    <dbReference type="STRING" id="564608.C1N1F7"/>
    <dbReference type="GeneID" id="9686996"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44735"/>
    <dbReference type="eggNOG" id="KOG0556">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HYSEEVI"/>
    <dbReference type="OrthoDB" id="372395at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000013">
        <property type="entry name" value="Aspartate--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="142"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH54186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="448" mass="50621" checksum="E09FF835233D0833" modified="2009-05-26" version="1">MTAARVNETVTLRGRVHNVRGKGKSAFLILRQQTATCVFFVDDVDVSKGMVKWVSKLEAESVIDISGVVAVPSEGPVVSCTQKEVELVVHSVYCVSRSIDDASRPESDFDKEDGAQYVRVLQDTRLNYRVIDLRTPANQAIFRVQSAVCELFREALRRKDFVEIHTPKLIGGASEGGASVFKLDYMGQPACLAQSPQLYKQMAIEADMDRVFEIGPVFRAENSNTHRHLCEFTGLDMEMTIKEHYSEVLDVLNDLFLHMFDGLNERFKHELEVVNAQHPFEPLKYLNPTLRLTFPEGIKMLQDHGVEGVDPLGDLSTEQERVLGQLVKEKYDTDFYILHKYPLNARPFYTMPCPHDGDYTNSFDIFIRGEEIISGAQRIHDVELLSKRAVECGIEIETIQAYIDAFKYGALPHGGCGVGLERVVMLFLNLGNIRKTSMFPRDPRRLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1W5</accession>
    <name>C1N1W5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_20767</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062190.1">
        <property type="nucleotide sequence ID" value="XM_003062144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1W5"/>
    <dbReference type="STRING" id="564608.C1N1W5"/>
    <dbReference type="GeneID" id="9687424"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20767"/>
    <dbReference type="eggNOG" id="KOG1752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RDETHGM"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF5">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="2">
        <location>
            <begin position="87"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="172" mass="18080" checksum="5524FE7B89D72994" modified="2009-05-26" version="1" fragment="single">MRALSFAARGRDAPPSPRGDAPRVQTRGEIKTSRGGLAAARGLTSSSSALLLLLSLLLLLLAAPAPARALAPPANAYVLQTVSAHDVVVFSKSYCPRSRGVIKVLLANGARDPFVVDVDRDETHGMHGVVDALSLLYGDKSIPQVFVKGQRIGGNDEFLSANATGELRRLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N276</accession>
    <name>C1N276_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51876</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062043.1">
        <property type="nucleotide sequence ID" value="XM_003061997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N276"/>
    <dbReference type="GeneID" id="9687483"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51876"/>
    <dbReference type="OMA" id="RRAFMLW"/>
    <dbReference type="OrthoDB" id="10486729at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910590" evidence="1">
        <location>
            <begin position="24"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="69" mass="7492" checksum="7CED94902248C60F" modified="2009-05-26" version="1">MGFIKAVAQQLVITGLLLGVAKRSGVISVHPRSISHETGRRAFMLWVGCSDSIVGQVDSLWHGFKNSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N282</accession>
    <name>C1N282_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_6221</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062245.1">
        <property type="nucleotide sequence ID" value="XM_003062199.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N282"/>
    <dbReference type="STRING" id="564608.C1N282"/>
    <dbReference type="GeneID" id="9687684"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6221"/>
    <dbReference type="eggNOG" id="KOG4837">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SKWEVAH"/>
    <dbReference type="OrthoDB" id="4150at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017506">
        <property type="entry name" value="PSII_S4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040591">
        <property type="entry name" value="RqcP2_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03069">
        <property type="entry name" value="PS_II_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13633">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13633:SF3">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17774">
        <property type="entry name" value="YlmH_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="2">
        <location>
            <begin position="169"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="244" mass="25953" checksum="A0A89B8B71C8B99B" modified="2009-05-26" version="1" fragment="single">ASIAERAEAASDAWSVHVTPFLDPALAADALAVVGRMADVDARPWGGYDRAERVRLVIGRAEVLDAPPACVSAYKLSGNFMFDAADHRDFLGAVLGTGIERDRVGDILVQGERGAQVLATPEMATFLSQARPALTSVRSVPVACAAAPLSDLRVPPPRVDAFNSVEASMRLDAIASAGFRMSRSKMSDLVTSGAVRVNWREGCKPKTVVATGDVISLRGKGRVEVGEVETTKKGKFSVQLTRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2H9</accession>
    <name>C1N2H9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_69850</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062092.1">
        <property type="nucleotide sequence ID" value="XM_003062046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2H9"/>
    <dbReference type="GeneID" id="9687315"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69850"/>
    <dbReference type="OMA" id="MTRATSX"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="250" mass="29753" checksum="6A026DC0441787C3" modified="2009-05-26" version="1">MLGMIRTVPTNERRASRDDDERRRGTSRSRRTSSPPRRLRVTSLRRAFYPKRQTTPSHPPPPRRLPSSSSFASRTPNGRRSRARTPPRSARRPTRDDPNRLERGRASAARSRTSPRRAAREKTRRASRRRDRETRTRGVRAAHTWRRRRRRRRRRLRRASSSPRWANRRAPRGGRRGGATRRRRRRRAAARFRFPPRSRPRRRRAPARRRRRRRRSAAAPRTRPRRRRRGASEAAAAATTTTRRRATPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N370</accession>
    <name>C1N370_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PSI-G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PSAG</name>
        <name evidence="11" type="ORF">MICPUCDRAFT_52059</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PsaG/PsaK family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062556.1">
        <property type="nucleotide sequence ID" value="XM_003062510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N370"/>
    <dbReference type="STRING" id="564608.C1N370"/>
    <dbReference type="GeneID" id="9687770"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52059"/>
    <dbReference type="eggNOG" id="ENOG502RZ2U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QNGESHF"/>
    <dbReference type="OrthoDB" id="494978at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.40">
        <property type="entry name" value="Chlorophyll a-b binding protein like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000549">
        <property type="entry name" value="PSI_PsaG/PsaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023618">
        <property type="entry name" value="PSI_PsaG/PsaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016370">
        <property type="entry name" value="PSI_PsaG/PsaK_pln"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34195:SF1">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT V, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34195">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT V, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01241">
        <property type="entry name" value="PSI_PSAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="139" mass="14372" checksum="56981B140ABC2F2C" modified="2009-05-26" version="1">MACLRAPALPARASPATFASKTRKSLAVRSTGGARKVSTNAFSDVNVVISGCNALALALGRFVWLPSIREKTAMQGPGVQNGESHFAAGDARAEEAASVFATNDPAGFTIVDLLMWGSIGHVVGYSALASQSFVDVFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N383</accession>
    <name>C1N383_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_2829</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NARF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062564.1">
        <property type="nucleotide sequence ID" value="XM_003062518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N383"/>
    <dbReference type="STRING" id="564608.C1N383"/>
    <dbReference type="GeneID" id="9688004"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2829"/>
    <dbReference type="eggNOG" id="KOG2439">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GYLHHVL"/>
    <dbReference type="OrthoDB" id="10253113at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000042">
        <property type="entry name" value="Cytosolic Fe-S cluster assembly factor NAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.950.10">
        <property type="entry name" value="Fe-only Hydrogenase (Larger Subunit), Chain L, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050340">
        <property type="entry name" value="Cytosolic_Fe-S_CAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11615">
        <property type="entry name" value="NITRATE, FORMATE, IRON DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="Fe-only hydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron hydrogenase large subunit C-terminal" evidence="6">
        <location>
            <begin position="105"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="388" mass="40523" checksum="3E7EDB88FC666643" modified="2009-05-26" version="1" fragment="single">FSGAVKLGDLNDFINPSQNCVVALTAGEVILQRRGAPPSDLPPGAPTIYGDPSAPTVKVSLSDCLACSGCVTSAETVLLEAQSADEFRARVRAAAMSGGRMVVVVSVVLDTTASRDLSLLESCEEFVSRYRNAKHAAVTNTPPPSPADVLPVLTSACPGWVCYAEKTHGGAVLNHVSAVKSPQQVMGCIVKRKIAAELGVPASAVFHATVMPCFDKKLEASREDFAMDDLGENVREVDCVLTTGEVAEMIAVAAGLGAPSSALAFNPRPRCLSTPPDAFQLHPVVRSGSGGYLDAVFRHAAKVLHGVDVTGPLKYATPSSRNLDLKEVTLEVDGAVVLRFAAAYGFRNIQNIVRKCKAGSVATGDAYDFVEIMACPSGCLNGGGQLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3N5</accession>
    <name>C1N3N5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68694</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062645.1">
        <property type="nucleotide sequence ID" value="XM_003062599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3N5"/>
    <dbReference type="GeneID" id="9688085"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68694"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="157" mass="17493" checksum="30B6064A097CBCF0" modified="2009-05-26" version="1">MACTTLNCGFWLRCHMRRLVARAHVATSDCAGTRGDSLRGHVWRLLPFLHHGGVACCARFRIGSSVIVPWRQRWRLHYCAVAAAFRVLDRVPGVCIGSTQLWKREGGAVALDLSARTKSLILLKCGRLIRSGSRRQRDTRNATNDEAPPCRAAREDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3U2</accession>
    <name>C1N3U2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68744</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062675.1">
        <property type="nucleotide sequence ID" value="XM_003062629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3U2"/>
    <dbReference type="GeneID" id="9687873"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68744"/>
    <dbReference type="OrthoDB" id="411785at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="611" mass="68105" checksum="C041B2D718BF9319" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4E7</accession>
    <name>C1N4E7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_52529</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PurH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062985.1">
        <property type="nucleotide sequence ID" value="XM_003062939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4E7"/>
    <dbReference type="STRING" id="564608.C1N4E7"/>
    <dbReference type="GeneID" id="9688218"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52529"/>
    <dbReference type="eggNOG" id="KOG2555">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IKHNNPC"/>
    <dbReference type="OrthoDB" id="6017153at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01421">
        <property type="entry name" value="IMPCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.20:FF:000001">
        <property type="entry name" value="Bifunctional purine biosynthesis protein PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000001">
        <property type="entry name" value="Bifunctional purine biosynthesis protein PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692:SF0">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="11">
        <location>
            <begin position="33"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00050488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH52924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="625" mass="66707" checksum="32E2385FB8732CAE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4Y1</accession>
    <name>C1N4Y1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flagellar inner arm dynein light chain Tctex1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_70830</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062873.1">
        <property type="nucleotide sequence ID" value="XM_003062827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4Y1"/>
    <dbReference type="STRING" id="564608.C1N4Y1"/>
    <dbReference type="GeneID" id="9688313"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70830"/>
    <dbReference type="eggNOG" id="KOG4081">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VNQWTSA"/>
    <dbReference type="OrthoDB" id="10059120at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21455">
        <property type="entry name" value="DLC-like_DYNLT1_DYNLT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.40:FF:000001">
        <property type="entry name" value="Dynein light chain Tctex-type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF4">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0243">Dynein</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH52812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="106" mass="11777" checksum="DA41E3B4C1DE7611" modified="2009-05-26" version="1">MQAIFVADDVNEIIKESIDAVLQNAAYSHAKVGQWTSSAVETTLRRLTALKKPFKYVVTCVIMQKNGAGLHTASSCYWDNETDGARTVRWENKSMYCIVTVFGLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5A0</accession>
    <name>C1N5A0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52866</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063135.1">
        <property type="nucleotide sequence ID" value="XM_003063089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5A0"/>
    <dbReference type="GeneID" id="9688575"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52866"/>
    <dbReference type="OMA" id="HAANFRD"/>
    <dbReference type="OrthoDB" id="532617at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019494">
        <property type="entry name" value="FIST_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10442">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01204">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FIST C-domain" evidence="2">
        <location>
            <begin position="568"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="747" mass="78369" checksum="B67E2285CC295A81" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5H1</accession>
    <name>C1N5H1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_63656</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063361.1">
        <property type="nucleotide sequence ID" value="XM_003063315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5H1"/>
    <dbReference type="GeneID" id="9688595"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63656"/>
    <dbReference type="OrthoDB" id="498906at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="300" mass="32280" checksum="CF1CC86F27B95060" modified="2009-05-26" version="1">MGNGPDPNAPPPQGGGGGALPPIHGARQGTPQSRPMSDPGPPPPGPPTNPPGAVNVPPSNVQGTHTSYSEPAIGVPIGGPQHPGPGAYYAGQQPYGAHSTQPGAAHHQQPGPHQYYHGAPAPINPHYNAHPHGGVAYLQTVEVHPGNYYHTLADGTTVRISEETLPVEHEEAVVLSKSLRIFSIIDVVLCVLYIITGLYWAMLAILGPIMGYVGAKNYSPGYTIVYFVFTLLNLVWKVAIFIINTDLFTRVLTALLVCVQIYIARLCWQFYKLIKHFSEIECITLRAFEGSMIYPARPGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N631</accession>
    <name>C1N631_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53138</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063264.1">
        <property type="nucleotide sequence ID" value="XM_003063218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N631"/>
    <dbReference type="GeneID" id="9688904"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53138"/>
    <dbReference type="OMA" id="WHRKVEA"/>
    <dbReference type="OrthoDB" id="435053at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="141" mass="15354" checksum="B1978E143DE0BD62" modified="2009-05-26" version="1">MPGMHGGIAGAVVQESNDYKYPPTPRTPAEDTPAARFKRLPKDDVLFLERLFSEFDVDESGGLGREQTGALIRRLNDGVAPTDEELDDVMREAAGDDGIVFVDELADVLKSWHRKVEAKRVAREGKKPQKSDGAVGSCAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N688</accession>
    <name>C1N688_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diphthamide biosynthesis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_22214</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 [3Fe-4S](0)-[protein] + 2 Fe(2+)-[Dph3] + NADH = 2 [4Fe-4S](1+)-[protein] + 2 [Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71239"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:17998"/>
            <dbReference type="Rhea" id="RHEA-COMP:18001"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[3Fe-4S](1+)-[protein] + Fe(2+)-[Dph3] = [3Fe-4S](0)-[protein] + Fe(3+)-[Dph3]</text>
            <dbReference type="Rhea" id="RHEA:71235"/>
            <dbReference type="Rhea" id="RHEA-COMP:17996"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:33751"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DPH3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063492.1">
        <property type="nucleotide sequence ID" value="XM_003063446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N688"/>
    <dbReference type="STRING" id="564608.C1N688"/>
    <dbReference type="GeneID" id="9688734"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22214"/>
    <dbReference type="eggNOG" id="KOG2923">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IYDPDMF"/>
    <dbReference type="OrthoDB" id="66964at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.660.10:FF:000001">
        <property type="entry name" value="Diphthamide biosynthesis 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF31">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DPH-type MB" evidence="8">
        <location>
            <begin position="3"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="71" mass="7962" checksum="4EA3CDB09D3FB8F5" modified="2009-05-26" version="1">MSSYDEVDLEDMEWNAELGAFTYQCPCGDLFQISPEELRAGEEIGHCPSCSLVITVVYEPEDLKTLIPEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6E7</accession>
    <name>C1N6E7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_48880</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063519.1">
        <property type="nucleotide sequence ID" value="XM_003063473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6E7"/>
    <dbReference type="STRING" id="564608.C1N6E7"/>
    <dbReference type="GeneID" id="9688766"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48880"/>
    <dbReference type="eggNOG" id="KOG4232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LSANWWN"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF30">
        <property type="entry name" value="DELTA 8-(E)-SPHINGOLIPID DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="14">
        <location>
            <begin position="37"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="121"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH52655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="527" mass="58780" checksum="2A76466EDD24668C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6G6</accession>
    <name>C1N6G6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_53278</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063334.1">
        <property type="nucleotide sequence ID" value="XM_003063288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6G6"/>
    <dbReference type="STRING" id="564608.C1N6G6"/>
    <dbReference type="GeneID" id="9688969"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53278"/>
    <dbReference type="eggNOG" id="ENOG502RMSV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ACESCAG"/>
    <dbReference type="OrthoDB" id="202764at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039647">
        <property type="entry name" value="EF_hand_pair_protein_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10891">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SAM" evidence="6">
        <location>
            <begin position="339"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="439"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="475"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="558"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="758"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="805"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1011"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1106"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1011"/>
            <end position="1032"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1156" mass="122763" checksum="CE4914BD7F180D37" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6J1</accession>
    <name>C1N6J1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase</fullName>
            <ecNumber evidence="4">1.14.13.81</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_49742</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Mg-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 O2 + 2 H(+) = 3,8-divinyl protochlorophyllide a + 3 NADP(+) + 5 H2O</text>
            <dbReference type="Rhea" id="RHEA:33235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58632"/>
            <dbReference type="ChEBI" id="CHEBI:60491"/>
            <dbReference type="EC" id="1.14.13.81"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AcsF family.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.81" evidence="4"/>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063553.1">
        <property type="nucleotide sequence ID" value="XM_003063507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6J1"/>
    <dbReference type="STRING" id="564608.C1N6J1"/>
    <dbReference type="GeneID" id="9688990"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49742"/>
    <dbReference type="eggNOG" id="ENOG502QRIH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FHPIFKW"/>
    <dbReference type="OrthoDB" id="524174at2759"/>
    <dbReference type="UniPathway" id="UPA00668"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048529">
        <property type="term" value="F:magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01047">
        <property type="entry name" value="ACSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01840">
        <property type="entry name" value="AcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008434">
        <property type="entry name" value="AcsF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003251">
        <property type="entry name" value="Rr_diiron-bd_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02029">
        <property type="entry name" value="AcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010172">
        <property type="entry name" value="PRK13654.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31053">
        <property type="entry name" value="MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER [OXIDATIVE] CYCLASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31053:SF2">
        <property type="entry name" value="MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER [OXIDATIVE] CYCLASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02915">
        <property type="entry name" value="Rubrerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rubrerythrin diiron-binding" evidence="12">
        <location>
            <begin position="145"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH51926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="414" mass="47645" checksum="6C97F7D08A4EE135" modified="2009-05-26" version="1">MASQTISMSATARVAARASLRSSRDTSRIARLPKSAARRAASSARLAVRAAGAAVDQETGIKKMREGIKEAADENLLTPRFYTTDFDEMEQLFSTEINPNLDEAELVAILQEFREDFNQKHFVRNDSFKKAADGITGESRRIFIEFLERSCTAEFSGFLLYKELGRRLKKTAPVCAEIFTLMSRDEARHAGFLNKAMSDFNLALDLGFLTKNRQYTFFKPKFIIYATYLSEKIGYWRYISIYRHLQENPNDQLYPLFQYFENWCQDENRHGDFFTACLKARPEFINDWEAKLWARFFCLSVYVTMYLNDHSRTEFYESIGLDTTQFNMHVIHQTNKTTAQIFPQVIDTYNPKFKEYLDNLRDINVKLSKAQSPMEKAPLIAGFAANLLGVALMKPVDSGSIDFVEDVNSPAFMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N784</accession>
    <name>C1N784_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_48995</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063853.1">
        <property type="nucleotide sequence ID" value="XM_003063807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N784"/>
    <dbReference type="GeneID" id="9689134"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48995"/>
    <dbReference type="eggNOG" id="ENOG502SDJM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WDQFPKL"/>
    <dbReference type="OrthoDB" id="10475109at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="349" mass="39277" checksum="794E8EF1C62B5829" modified="2009-05-26" version="1">MPASSLAARVSLPFALSKRAKAPVSRRSASVRASAALNHKGRTALTGILRVPQEKESEVDAMWRSHEVMMQKTHKVYDGELEDDFTDGPRLLEFYVSKAVEKTNPLDPASPDSGHILYCVNEKYVAPEGLAEHMRVGAEQWDQFPKLMEFIRDYSPFMTTNGEIFTNYVDRAPACTARKGDTTINLGFVVPQSMERTVDALWKSHEEFMRETHDFGEGPTNDPTRPRLTQFTITKARELVNPMDPTEGFTGNLQYSMQETYASKDGIAKHMAFNDPKSGYAALFEALMPLLEEPYVRYADVGQGVVITSMQKGGFNSNIVGGFKELLDKVLPRRAPHEEYCEEYCPETW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N797</accession>
    <name>C1N797_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_22841</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063699.1">
        <property type="nucleotide sequence ID" value="XM_003063653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N797"/>
    <dbReference type="STRING" id="564608.C1N797"/>
    <dbReference type="GeneID" id="9689301"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22841"/>
    <dbReference type="eggNOG" id="KOG0034">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MMVGIQV"/>
    <dbReference type="OrthoDB" id="495428at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46971">
        <property type="entry name" value="CALCINEURIN B SUBUNIT (PROTEIN PHOSPHATASE 2B REGULATORY SUBUNIT)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46971:SF1">
        <property type="entry name" value="CALCINEURIN B SUBUNIT (PROTEIN PHOSPHATASE 2B REGULATORY SUBUNIT)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="29"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="93"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="193" mass="21847" checksum="DCFC70692F5450F7" modified="2009-05-26" version="1">MGLTASSLNLTQYDVEEVQEHCGGRFNHREIQCLYKRFRALDKRHKGYVSEDELLSIPELAISPLASRVVQVFQNLNFKDFVLMLAAFSDRASREEKLEFMFRVYDVDRDGFISLSDLETIVKHLVGSSLNEEQVALLITRAMGELAERRKRDKRFRDGDGNAGSGGITFGEFQVILEGAEKLPNVVVPVGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7L0</accession>
    <name>C1N7L0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_23204</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Prolyl cis/trans isomerase with specificity for phospho-Ser-Pro bonds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PpiC/parvulin rotamase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063921.1">
        <property type="nucleotide sequence ID" value="XM_003063875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7L0"/>
    <dbReference type="STRING" id="564608.C1N7L0"/>
    <dbReference type="GeneID" id="9689558"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23204"/>
    <dbReference type="eggNOG" id="KOG3259">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DEVQCLH"/>
    <dbReference type="OrthoDB" id="2530521at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000010">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase Pin1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051370">
        <property type="entry name" value="PPIase_Pin1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10657">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10657:SF4">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="8">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="115" mass="12137" checksum="7BEBBF08B2CEA160" modified="2009-05-26" version="1">MEVRASHLLVKHQGSRRAASWRDPDGVVITKRTKAAAMDELMAYKAEIDAGNVTFADLAAKVSDCSSAKHGGDLGFFGPGKMQKAFEDGAFALEVGAMSGVVDSDSGLHIILRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7P5</accession>
    <name>C1N7P5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53779</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063943.1">
        <property type="nucleotide sequence ID" value="XM_003063897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7P5"/>
    <dbReference type="GeneID" id="9689384"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53779"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="145" mass="15768" checksum="1364092FD9B67AFB" modified="2009-05-26" version="1">MTDDSRSLRRRTFTVLLMTPPGRRVSESLTSAATATWDFGDVLKGHAEPYERNERNGGGGGGGASCPSPNAPRAVARETARRSMTFSDGDHFAEDDAASGERDTPRGDRRASSSFPERPRSLSDAKARSIHWFPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7W1</accession>
    <name>C1N7W1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_5567</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064160.1">
        <property type="nucleotide sequence ID" value="XM_003064114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7W1"/>
    <dbReference type="GeneID" id="9689601"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5567"/>
    <dbReference type="eggNOG" id="ENOG502QR9S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="STKHKWK"/>
    <dbReference type="OrthoDB" id="361580at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080120">
        <property type="term" value="P:CAAX-box protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43592">
        <property type="entry name" value="CAAX AMINO TERMINAL PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43592:SF24">
        <property type="entry name" value="CAAX AMINO TERMINAL PROTEASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="2">
        <location>
            <begin position="138"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="229" mass="25887" checksum="A5346A6952EDD4D9" modified="2009-05-26" version="1" fragment="single">VPWNAGLVFQVMILWFAAFLLVGHVGLPSVVTWLGFNCRELSARGLALYSLSADVVEMFVGLGVLYQCLRPYFPLPKRWFPIALKGRWWMEILRGCVAFPIVTATVNLNSAMMPVSSASLPMSPWEQVMISNDILSVCFYIGVVSLVAPVWEEMIFRGFLMPSLTRYFRMDVAIVLSSFLFAAAHFSMERLLPLTVLGMLMCVVYIRSKNILAPIVLHSLWNFCAFFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7W7</accession>
    <name>C1N7W7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sphingolipid delta(4)-desaturase DES1-like</fullName>
            <ecNumber evidence="8">1.14.19.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_49081</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Sphingolipid-delta-4-desaturase required for the biosynthesis of delta-4-unsaturated sphingolipids and derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:46544"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:31488"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="EC" id="1.14.19.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.17" evidence="8"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064164.1">
        <property type="nucleotide sequence ID" value="XM_003064118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7W7"/>
    <dbReference type="STRING" id="564608.C1N7W7"/>
    <dbReference type="GeneID" id="9689422"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49081"/>
    <dbReference type="eggNOG" id="KOG2987">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GATCNQN"/>
    <dbReference type="OrthoDB" id="200948at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042284">
        <property type="term" value="F:sphingolipid delta-4 desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03508">
        <property type="entry name" value="Delta4-sphingolipid-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011388">
        <property type="entry name" value="DES1/DES2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013866">
        <property type="entry name" value="Sphingolipid_d4-desaturase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879">
        <property type="entry name" value="SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879:SF8">
        <property type="entry name" value="SPHINGOLIPID DELTA(4)-DESATURASE DES1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08557">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017228">
        <property type="entry name" value="Sphnglp_dlt4_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01269">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingolipid delta4-desaturase N-terminal" evidence="10">
        <location>
            <begin position="9"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH51786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="327" mass="36980" checksum="60ECEB1D7AC0060F" modified="2009-05-26" version="1">MSSGALEAKTKGDFYWSKDDEPHARRRREILAKYPQIKDLYGADMWSFPQIVAVVFTQLAAAYYLGNNAPMPVLVLAAYSLGGFATANLFLANHELSHNLVFENTTANRALGLFANLPVGIPFSVAFKRYHMEHHLFQGHDGVDTDIPTKGEAAVFSVGGALLKTVWVMGQLFFYALRPMLVSPKPMKAWDCLNLVTQVGFDFAFVYLAGPRAMLYLLLSVFLGGGLHPIAGHFISEHYVFEPGQETYSYYGPLNFLVYNVGYHNEHHDFPKVPGSRLHKIREIAPEYYDTLKYHTSWTKVIFEYIMDPSMGPFSRTMRRRKSAKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N825</accession>
    <name>C1N825_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_53918</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064008.1">
        <property type="nucleotide sequence ID" value="XM_003063962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N825"/>
    <dbReference type="GeneID" id="9689636"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53918"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="164" mass="16928" checksum="6E16C4758C5B3121" modified="2009-05-26" version="1">MAAAARPVAPRARLAARAAATTTRRDVDRAVAPPTRRSLLAATTTTLLLATTAAVARAAEEAETDDGTRVIISTSSAATAAVASPLECASDPSCVVARDASLAGGGSYAPPTEFVEEDPDGALRRAICPRNPTADICRSVKDRKKINDSPCLIPIGLACAMWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8T3</accession>
    <name>C1N8T3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_43408</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM214 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064504.1">
        <property type="nucleotide sequence ID" value="XM_003064458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8T3"/>
    <dbReference type="STRING" id="564608.C1N8T3"/>
    <dbReference type="GeneID" id="9689769"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43408"/>
    <dbReference type="eggNOG" id="KOG4467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019308">
        <property type="entry name" value="TMEM214"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13448">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13448:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="674"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="70"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH51409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="728" mass="74263" checksum="B70B97AF8DF21908" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N914</accession>
    <name>C1N914_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_54324</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064377.1">
        <property type="nucleotide sequence ID" value="XM_003064331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N914"/>
    <dbReference type="GeneID" id="9689818"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54324"/>
    <dbReference type="OMA" id="ANAHHAI"/>
    <dbReference type="OrthoDB" id="442947at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="735"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="305"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="305"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="866" mass="88426" checksum="DEDDBD96D86CA115" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9C6</accession>
    <name>C1N9C6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_54452</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064594.1">
        <property type="nucleotide sequence ID" value="XM_003064548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9C6"/>
    <dbReference type="GeneID" id="9689872"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54452"/>
    <dbReference type="OrthoDB" id="205639at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="135"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="185"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="215"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="394"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="694"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="733"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="637"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="394"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="749"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="939" mass="100221" checksum="CC12B7BC4DA2A1D2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9L9</accession>
    <name>C1N9L9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54534</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH50968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064634.1">
        <property type="nucleotide sequence ID" value="XM_003064588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9L9"/>
    <dbReference type="GeneID" id="9690080"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54534"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040884">
        <property type="entry name" value="SLATT_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18181">
        <property type="entry name" value="SLATT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMODS and SLOG-associating 2TM effector" evidence="2">
        <location>
            <begin position="3"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH50968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="111" mass="12496" checksum="187FED489814FF2E" modified="2009-05-26" version="1">MAEWVALTVAVGQAAQQWLRENRIEEQRIAYRQASAELADAKMKWEAVPMEKRAMQSKIDELVLRVETAIVSVVEPLPQSCNCPSLEVLVERSESAEEGEEKKKEGKGLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA77</accession>
    <name>C1NA77_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_43709</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064858.1">
        <property type="nucleotide sequence ID" value="XM_003064812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA77"/>
    <dbReference type="GeneID" id="9690186"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43709"/>
    <dbReference type="OrthoDB" id="47172at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin-like" evidence="3">
        <location>
            <begin position="12"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="319" mass="35453" checksum="BF442F041FFB5FD7" modified="2009-05-26" version="1">MYPFPVCHAYDGYSMVDLANIDYVKYPRIVDVRGDVAVCRPGDVLFVPDGWWRHEQGLSGDACGNAHVDVRVATGARPRTRACATLAVGRVVEQRITREEGAKDARRWLEVVKNAEEAEWLDLGTVEGQRRIDTAQVLRDEIDIGLPPPPPAADDTKNGSKTGVTTTATLNKKRKHARARGRGRWPSFLADLIDGRMLPTDWLNDDFVDPLLLSEAEAAMKKAALTGEDDANETTSRQLATVKTPSDADFAIALPDGGVLTRRAKILKDDREAYERAHPEFFVNKLRDKGWDAKYTPMSVLNPDHPDFIGKKPPNPMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAC5</accession>
    <name>C1NAC5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_70793</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064940.1">
        <property type="nucleotide sequence ID" value="XM_003064894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAC5"/>
    <dbReference type="GeneID" id="9690319"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70793"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00761">
        <property type="entry name" value="Glyco_tranf_GTA_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="1">
        <location>
            <begin position="188"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="403" mass="45452" checksum="89B001F7BBF7CEEB" modified="2009-05-26" version="1">MAIAYGYLHRKARRAGSNGKKSWIVFFSYESTFVRKYESTKVLVLSKVPSYDSTFVLSYFRKYSRKYFRTFVRTTFVVSYKVRAMQASRLASSYLRTYFRKNFRKYLPRFCALSHSLRPLPASTSPGVAGVDGASLSVFDCNIVHLCCLRYLHVLSLHVTGSLRDGITNRHVTICIPALPNDLLEGGGETFRHTLNSIRVQTLPPREVIVGLSESTASEGSNFCHEFREILEGIPLRIITTTSKGSVGAKRNRAAVTARSRYVTFFDADGDVIHPRRIELIQMAFERYSDSVLVLHTFTSEKVVAAEDVASFSVVSPKELCTANKQPIRSNAFNRLIGSDTREWLLPVLPDIHHGYLSVRTDFVSSTPFSEDFDGREDSSFVNTVVEKTSCSSARLAFFYELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAI9</accession>
    <name>C1NAI9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_54930</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064917.1">
        <property type="nucleotide sequence ID" value="XM_003064871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAI9"/>
    <dbReference type="GeneID" id="9690357"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54930"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="3">
        <location>
            <begin position="12"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH50897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="148" mass="16795" checksum="2AA1E96D9210A633" modified="2009-05-26" version="1">MGFSEVARRLSTRHVPYTERKKQAIWAGSTTGVPCYDIGPCASSCNELERVKLVRYFNNITWLNLRLSNAVQWCHGSAAALKDEGLLGDHVQEDEWAQYRGVLDIDGNVDAWGLRWRLESGSVVFLVKSSYEHFFSNSLVDGTHYVHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGL3</accession>
    <name>C1MGL3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_70228</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054795.1">
        <property type="nucleotide sequence ID" value="XM_003054749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGL3"/>
    <dbReference type="GeneID" id="9680599"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70228"/>
    <dbReference type="OMA" id="LDPKMSG"/>
    <dbReference type="OrthoDB" id="496380at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="237" mass="25043" checksum="643A187A95F7633D" modified="2009-05-26" version="1">MSSSSCATMSPSSRVRVSPARSPRRSTTSAIRRRTMTIVAKATSPAALKSAASPATATSPATAPAVKAEKGEFVFEAPNQYGYFDSAIEAAETKRAKRLEQGYVPITGLSADEEASRYARLCSKHPTAARCAEGFSKKIVTKPATQSMVNGSMVRSDGIILVPGNREDLITWALDPKMSGDTLGLLLPTLFVIIGAQLKQVAGVPEYVSGAVGITTKIIATCLVALYWLPDFTAGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGL6</accession>
    <name>C1MGL6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_70811</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055343.1">
        <property type="nucleotide sequence ID" value="XM_003055297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGL6"/>
    <dbReference type="GeneID" id="9680290"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70811"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="298" mass="33309" checksum="8C915A315FB06C84" modified="2009-05-26" version="1">MVAWVNMRIDAGGLRVAQTSASRKVLRALARRGDEAEREDAARSSSSLSEACERFEDADDVPFRLLRRACEASRAEKMKKMKKKKDDDDDDDDDDDGPYLQDVMLGSKLVLTAPRLPPVDPEHAARMAKLREEVDERRRRAMRLRESAEEGDAEGDAEGDAGTSGVSMLAKDLGFGAHVLTVVVASGVAGVLAGASRRVREETFFFFQRDAAPTPRLPLPRRQIDGPGQRHDAHRDRGDGRVRRAGRGSPPFHPPRREDVGAARRETREKTFDDETRDDWNRIRCVLYTGSHTTAFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGT6</accession>
    <name>C1MGT6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein HYP13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HYP13</name>
        <name evidence="1" type="ORF">MICPUCDRAFT_70662</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054832.1">
        <property type="nucleotide sequence ID" value="XM_003054786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGT6"/>
    <dbReference type="GeneID" id="9680871"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70662"/>
    <dbReference type="OMA" id="ESELRWC"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="822" mass="89803" checksum="5D1F8E3809A271F5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGX4</accession>
    <name>C1MGX4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_46151</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055395.1">
        <property type="nucleotide sequence ID" value="XM_003055349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGX4"/>
    <dbReference type="GeneID" id="9680271"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46151"/>
    <dbReference type="eggNOG" id="ENOG502T2JY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DEGWAPR"/>
    <dbReference type="OrthoDB" id="513668at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="153" mass="17213" checksum="4E8F53F3D44211A7" modified="2009-05-26" version="1">MLRTIARNNELARRTLLARVAGASQQSRTFISFDAKYSDEMPLGDAATRIGASFGPALDMIAEAQRKREPVAKKEDTIYVPELPHIFPIARLAAKSEFVRDVLVVDESKRVKPRLSWYDPYDTSWVPTGWFKDGVVADVEYYFGDKAVKVGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHE3</accession>
    <name>C1MHE3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_50146</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054942.1">
        <property type="nucleotide sequence ID" value="XM_003054896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHE3"/>
    <dbReference type="STRING" id="564608.C1MHE3"/>
    <dbReference type="GeneID" id="9680959"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50146"/>
    <dbReference type="eggNOG" id="KOG0336">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10256233at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050547">
        <property type="entry name" value="DEAD_box_RNA_helicases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963:SF8">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="168"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="394"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="7">
        <location>
            <begin position="702"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="550"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="666"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="728"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="564"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="747" mass="80656" checksum="D47BB131A793499B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHZ2</accession>
    <name>C1MHZ2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61474</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055039.1">
        <property type="nucleotide sequence ID" value="XM_003054993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHZ2"/>
    <dbReference type="GeneID" id="9681144"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61474"/>
    <dbReference type="OMA" id="HDAGAVY"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="343" mass="37958" checksum="AC5D822A3771C528" modified="2009-05-26" version="1">MLGSGCQKRPRHGGLRLRPARRVASGRARHPRGLREPRRGGGRAVRARNPVRRRGEHHEHPQGRGARRQAVARAAASAAGDRARARGRARGRPSGNRGGVRGDPRLDRGGRRLGRRRRRRRAMARGRAVARATEAGRGDRDVRRDSRADALAGRTRTRTRKTREGRVRARTRVEPRARLGGARPRARPRPRPRPRPRPRPRARGVAAAAGARELETRRVRLPRRLVPGFESSRAAGHHLGLPRRRSRARRRASLHAHAREEHPDSSAAAAGASPRAGRPRTRRGVRRSHGRGVRAGYHKRSSHERARSRASQFYGVRALGGAVDGRATVVHDAGAVYDSESAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI15</accession>
    <name>C1MI15_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_50398</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055051.1">
        <property type="nucleotide sequence ID" value="XM_003055005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI15"/>
    <dbReference type="STRING" id="564608.C1MI15"/>
    <dbReference type="GeneID" id="9681155"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50398"/>
    <dbReference type="eggNOG" id="KOG2597">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CFPVVYC"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10590">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041417">
        <property type="entry name" value="NPEPL1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963:SF4">
        <property type="entry name" value="AMINOPEPTIDASE NPEPL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="LEUCINE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18295">
        <property type="entry name" value="Pdase_M17_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosol aminopeptidase" evidence="6">
        <location>
            <begin position="447"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="562"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="626" mass="63914" checksum="2DD5CECA0BE67BF1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI45</accession>
    <name>C1MI45_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_50432</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055603.1">
        <property type="nucleotide sequence ID" value="XM_003055557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI45"/>
    <dbReference type="STRING" id="564608.C1MI45"/>
    <dbReference type="GeneID" id="9680586"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50432"/>
    <dbReference type="eggNOG" id="KOG1868">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HEFLCEC"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF827">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="4">
        <location>
            <begin position="371"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="550"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="761"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="803"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="570"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="773"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="839"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="937" mass="98065" checksum="091ED0B9114F571C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI72</accession>
    <name>C1MI72_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50461</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055077.1">
        <property type="nucleotide sequence ID" value="XM_003055031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI72"/>
    <dbReference type="GeneID" id="9680822"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50461"/>
    <dbReference type="eggNOG" id="ENOG502STJB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WSIAPSH"/>
    <dbReference type="OrthoDB" id="189346at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="160" mass="17688" checksum="585D111B6E6F9A0B" modified="2009-05-26" version="1">MALITAQQYIQAFVVVMAVYAAQMLLVPAKMVTDHFKAPATPMVQFWIRGASVAWGGLAYCVYTMPTAAALPVATAASVACNVLYPMNAKFGLIGAKKLPVKYPMHYVRHVTFQRVVESESIDRPRFAFRRRAAAATSPRWLHGVRRARADSSVTRNSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIM0</accession>
    <name>C1MIM0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_46356</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055154.1">
        <property type="nucleotide sequence ID" value="XM_003055108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIM0"/>
    <dbReference type="STRING" id="564608.C1MIM0"/>
    <dbReference type="GeneID" id="9680251"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46356"/>
    <dbReference type="eggNOG" id="ENOG502SC5Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HAYFERE"/>
    <dbReference type="OrthoDB" id="21204at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15315:SF26">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NRDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15315">
        <property type="entry name" value="RING FINGER PROTEIN 41, 151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="237"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="294"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="344"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="377" mass="40549" checksum="C835135E610D5941" modified="2009-05-26" version="1">MPIPVVGIYIGYIVARVLFRSAIEFFVRERGAINACLRKFQPPRGGPKLNLATALADIADANRSLADAETLPELPRAGWRYRCDLVYNSHAGQRAFFRALRVGPKLASVVGSVSVDVEEVPASSRGAAAAARGAAAEEEEEDDAAPAAAARGGDDGEIEVADEAAAAADDDDGFEHVGACRRMTLAQFYTMLRPALAQIAVDALASSSFATTTRPPRRVRIAGGENDDDDDDDARLCSICMDGEVEIVTKCAHAFCEACHLRWLSMSRECPLCRETLGREVSGTNDGSYSLVEWTYAGDDDDGDGDGGGGGGDDDTEAEAEAAAEATSTAERVDAAWLRRRMREFPAVSEPGRRPHERWLARRAAEKAKRRATDHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIM9</accession>
    <name>C1MIM9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_50628</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055159.1">
        <property type="nucleotide sequence ID" value="XM_003055113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIM9"/>
    <dbReference type="STRING" id="564608.C1MIM9"/>
    <dbReference type="GeneID" id="9680217"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50628"/>
    <dbReference type="eggNOG" id="ENOG502QRQR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QMAIDGC"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48466:SF2">
        <property type="entry name" value="OS10G0509000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48466">
        <property type="entry name" value="OS10G0509000 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein MutS core" evidence="6">
        <location>
            <begin position="34"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="7">
        <location>
            <begin position="434"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="333"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="758"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="184"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="662"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="759"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="839" mass="87331" checksum="CA08FA7ED62683D0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ88</accession>
    <name>C1MJ88_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dpy-30 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_50851</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dpy-30 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055791.1">
        <property type="nucleotide sequence ID" value="XM_003055745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ88"/>
    <dbReference type="STRING" id="564608.C1MJ88"/>
    <dbReference type="GeneID" id="9680902"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50851"/>
    <dbReference type="eggNOG" id="KOG4109">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="417678at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22965">
        <property type="entry name" value="DD_DPY30_SDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007858">
        <property type="entry name" value="Dpy-30_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049629">
        <property type="entry name" value="DPY30_SDC1_DD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05186">
        <property type="entry name" value="Dpy-30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="62"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH61043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="175" mass="18770" checksum="FE81A25A711ECC50" modified="2009-05-26" version="1">MPEEPPVDGALPRATDALDRRLATTRRPPRSRPSRLPRPGPRPRRFSLTVRFAVVARSCAAEVEGEEAAAPEPEPVPASEDAGYDNPEAAAAAQEAALATQNKLDVQALPIRQYLEQAVVPILLQGMQALVKERPGNPVEYLAAYLLKNNPQGPSNPPPEKALANPPPPEAEASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJP1</accession>
    <name>C1MJP1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55040</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056247.1">
        <property type="nucleotide sequence ID" value="XM_003056201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJP1"/>
    <dbReference type="GeneID" id="9681420"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55040"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="100" mass="10388" checksum="52DB76744B723001" modified="2009-05-26" version="1">MERPKVDGALNAILTDMIGLMRGAIDRLDALPDEPGCGWKKDEPACDFGCVAGELCVANKPWVAETKTETREAAAAAARESPLNPGGETDEAGDGDGDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJY8</accession>
    <name>C1MJY8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_8276</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056295.1">
        <property type="nucleotide sequence ID" value="XM_003056249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJY8"/>
    <dbReference type="GeneID" id="9681295"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8276"/>
    <dbReference type="eggNOG" id="KOG1108">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YARGMPY"/>
    <dbReference type="OrthoDB" id="10257697at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005496">
        <property type="term" value="F:steroid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF4">
        <property type="entry name" value="NEUFERRICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0754">Steroid-binding</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="3"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="130" mass="14298" checksum="1A1D7821ED0E3334" modified="2009-05-26" version="1" fragment="single">RLVTPDELATRNGVDDPSLWLAIVGRVFDVTRGGGARHYARGMPYAGFVGRDGTRAFATGRFDEDGLVPDVDGLSDDEILGVRRWLEFYEGGSEERDAYREIGVLAGGHYYDANGVETRRKLAFDAAANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKS7</accession>
    <name>C1MKS7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46543</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056047.1">
        <property type="nucleotide sequence ID" value="XM_003056001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKS7"/>
    <dbReference type="GeneID" id="9681361"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46543"/>
    <dbReference type="OrthoDB" id="10257430at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="270" mass="29598" checksum="ED7E45D9C7942855" modified="2009-05-26" version="1" fragment="single">MAHAPPGQPEGPDTTPIRAGRRRRRPPLAASSSSSDDDAYDGDDASRSLRRSMYSAESRTTRRFTNASSSDDDDDDARREDTLRARVRGDLRRNVRDLASTSSRGPLSGEWFVACNALSRVAEYCVLEMRSAPSSKHAPDATLWERDDAIAPRFVLEEGKLNVVIRALSELCVFTGVGGGEESSSSTREDVGGRAGSGLSLDDAVTSAAYNHRVDETVVREKLREFERAGGVVLERCLTFVECVQTCDFDELMEHCARVLAEASEESFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKU4</accession>
    <name>C1MKU4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_14114</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056447.1">
        <property type="nucleotide sequence ID" value="XM_003056401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKU4"/>
    <dbReference type="STRING" id="564608.C1MKU4"/>
    <dbReference type="MEROPS" id="S14.A01"/>
    <dbReference type="GeneID" id="9681365"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14114"/>
    <dbReference type="eggNOG" id="KOG0840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EIMHHKS"/>
    <dbReference type="OrthoDB" id="2017408at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF12">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="209" mass="22888" checksum="FFE0CB825170B333" modified="2009-05-26" version="1" fragment="single">QSKGPPPMVMERFQSVATQLMNQRIIRLGGAVDDDSCNLIVAQLLWLDAADPNQDITIYVNSPGGSVTAGMAVFDTMRHVRPNVSTVCVGLAASMGKFTYEIHLRPPYLFSYSLPNSRIMIHQPLGGAQGQAADIEIQANEIMHHKSTLNGYLAEFTGKPLEMVMEDTDRDFFMSATEAKEYGLIDTVIEHPTDVAVRSSGIPLYAGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML54</accession>
    <name>C1ML54_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="14">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_55580</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="function">
        <text evidence="12">Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 19">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="14"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056116.1">
        <property type="nucleotide sequence ID" value="XM_003056070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML54"/>
    <dbReference type="STRING" id="564608.C1ML54"/>
    <dbReference type="GeneID" id="9682004"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55580"/>
    <dbReference type="eggNOG" id="KOG0480">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RHQQTDK"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000347">
        <property type="term" value="C:THO complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000115">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 14" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="16">
        <location>
            <begin position="363"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="841"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="854"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00053280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH59492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="889" mass="99336" checksum="489EB35125576A2E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLD6</accession>
    <name>C1MLD6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55676</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056148.1">
        <property type="nucleotide sequence ID" value="XM_003056102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLD6"/>
    <dbReference type="STRING" id="564608.C1MLD6"/>
    <dbReference type="GeneID" id="9682026"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55676"/>
    <dbReference type="eggNOG" id="ENOG502R368">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10258312at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038929">
        <property type="entry name" value="CCDC13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31935">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31935:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="69"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="352"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="432"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="461" mass="52382" checksum="EAF9785FA3489A62" modified="2009-05-26" version="1">MPELKSDVPASEQRSNFTWVDFKQVQELTRRNQELTKILDLREREVAHITALLETKGDVLTAGVRKSKIIEVAKKNRELKLAVEREKAEKERLQTELKKLQTKLKTHTSDIDRTESPVETAYREVVAEASETAELARKELAVWKEKATHVAAWAERSSGRYTTVKAENDRLRLIIKREVGDAAEDLNRLEEASIKQGPGGWRGRAQQIQKLRNENTLLKQKLGRIEDLQSFGRGQVTVPEIEMKQTHIRAEALADVRSDNEYLEKKLKQTALRKNLVEKELRVVREKVNVLTEKCSNDDKLISALQLAIRRKIDSRVTEGSGTGLPGQATFQGSFAGNVVPAVMHHAVERRAHAQEQQIQVQNRIVQEMRQQNLQLRAKIATMEYDSGKNTRIREKYSSHNSEYSLPSGGDGMSVMLSDQNVEDVETLISHAEGLERLVELLKGKLSVTEAQVEHLRKQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMB0</accession>
    <name>C1MMB0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56460</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057372.1">
        <property type="nucleotide sequence ID" value="XM_003057326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMB0"/>
    <dbReference type="GeneID" id="9682338"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56460"/>
    <dbReference type="OrthoDB" id="10451618at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="602" mass="63370" checksum="EFF198018CEC6CAB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMC6</accession>
    <name>C1MMC6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pachytene checkpoint protein 2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_14739</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. PCH2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056908.1">
        <property type="nucleotide sequence ID" value="XM_003056862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMC6"/>
    <dbReference type="STRING" id="564608.C1MMC6"/>
    <dbReference type="GeneID" id="9682347"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14739"/>
    <dbReference type="eggNOG" id="KOG0744">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NGPHEKF"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051598">
        <property type="term" value="P:meiotic recombination checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000680">
        <property type="entry name" value="pachytene checkpoint protein 2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044539">
        <property type="entry name" value="Pch2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058249">
        <property type="entry name" value="Pch2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991:SF1">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23242">
        <property type="entry name" value="AAA_lid_TRIP13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="179"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="449" mass="48550" checksum="2D1A921594E509E0" modified="2009-05-26" version="1">MDTAAASPAPTSAVNAARKAPLSVYACMRSTSVAKREDVEAAMRSHVEASGVVPYEEGFALAIPSEASNAFLHANVESAVVSDLGDFDELRIPEGSPVSYHQLDLRVFAYQLDEDGPGEEMDGEDDVATFREWTLPSRDFHGLWESLVFDSDVKTRLTRYAGNALLFSEREVDPNLIAWNRVVLLHGPPGTGKTTMCKALAQRLSTAFSKTYESATLVEVNAHSLFSRWFSESGKLVGRLFQKIQDLCEDEKQLVFVLVDEVESLAAARKAAASGGEPGDAIRVVNALLTQIDALKKNPNAMVLTTSNITEAIDVAFVDRADIKAYIGPPGLRARYSILHSATLELVGKGLVQAPGSMALPEGFNRIAIETVTAVLKGGIVNDGTYANAALLRASAACEGMSGRALRKLPFLAYAIEHRDGRCELLDFLNAIAKAVMSERRDREKLAMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMJ7</accession>
    <name>C1MMJ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peroxisomal protein importer family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_45395</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxisomal targeting signal receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056940.1">
        <property type="nucleotide sequence ID" value="XM_003056894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMJ7"/>
    <dbReference type="STRING" id="564608.C1MMJ7"/>
    <dbReference type="GeneID" id="9682857"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45395"/>
    <dbReference type="eggNOG" id="KOG1125">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RISLGCC"/>
    <dbReference type="OrthoDB" id="10006023at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005052">
        <property type="term" value="F:peroxisome matrix targeting signal-1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024111">
        <property type="entry name" value="PEX5/PEX5L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130:SF0">
        <property type="entry name" value="GH08708P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="464"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="569"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="603"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="637"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="124"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="707" mass="75178" checksum="5ABBBEE9D864EA26" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN40</accession>
    <name>C1MN40_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56768</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057039.1">
        <property type="nucleotide sequence ID" value="XM_003056993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN40"/>
    <dbReference type="GeneID" id="9682478"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56768"/>
    <dbReference type="eggNOG" id="ENOG502S5ZD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SMNITTY"/>
    <dbReference type="OrthoDB" id="507659at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Flavin reductase like" evidence="3">
        <location>
            <begin position="114"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="268" mass="28495" checksum="B8F98D357733A001" modified="2009-05-26" version="1">MPGPVMSFALGLGLGVGVRVHVASRRREKKRTRRGGRSSRDAAVDAVPSARVDDALRRASLMAMRRRPTPRNYRVTAPTAALESSSDAADADADAETTPAPPPPPPPYASLSVPVYSLATAPTSPAGDSAGVASMNITTYACPVTIKPSRRMAVALYTHTATARNMLATGRGVLQVLRKRHAPLVELLGKRSAHDCDKMKALRDDFGIAVVERYGVRTIADVAGVMELKIVSIEHAGDHHLALCDVGEYESFEGDGEVLYTGDLPKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNQ2</accession>
    <name>C1MNQ2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46601</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057149.1">
        <property type="nucleotide sequence ID" value="XM_003057103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNQ2"/>
    <dbReference type="GeneID" id="9682588"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46601"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="234" mass="27988" checksum="2A7DBD25C55BD2DC" modified="2009-05-26" version="1" fragment="single">RRPRDGGGDGGGRRRVRTRRARRALVERGRDDGLDQRDVRAEVAHRPLALSLAIERGSFRREKRAFETRGDVPRAVSARARPRLEANALGVERGGESPRRGHRARRGVDAFRRERRRRRRRERRQSRVDRQREDAVVRRDFLPPRRRGRVRVGVARLFARRVFVVFVLGPPRAVVRVVVVGRGRGRDGEDADRRRLSPHGLRARRRRRRRRRRRRRRRRRRLRGRLRDHRVHEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNW7</accession>
    <name>C1MNW7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.131</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_62070</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:29523"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="EC" id="2.4.1.131"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:29524"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.131" evidence="3"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057183.1">
        <property type="nucleotide sequence ID" value="XM_003057137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNW7"/>
    <dbReference type="STRING" id="564608.C1MNW7"/>
    <dbReference type="GeneID" id="9682167"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62070"/>
    <dbReference type="eggNOG" id="KOG1387">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WKHFTLI"/>
    <dbReference type="OrthoDB" id="2276068at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031814">
        <property type="entry name" value="ALG11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15924">
        <property type="entry name" value="ALG11_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="15">
        <location>
            <begin position="47"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="15">
        <location>
            <begin position="148"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="14">
        <location>
            <begin position="313"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="285"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF15924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH58828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="520" mass="55912" checksum="C38F113188F7B595" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP62</accession>
    <name>C1MP62_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">intramembrane prenyl-peptidase Rce1</fullName>
            <ecNumber evidence="10">3.4.26.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_38670</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic sidechains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.26.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase U48 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.26.1" evidence="10"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057230.1">
        <property type="nucleotide sequence ID" value="XM_003057184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP62"/>
    <dbReference type="STRING" id="564608.C1MP62"/>
    <dbReference type="MEROPS" id="G05.002"/>
    <dbReference type="GeneID" id="9682204"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38670"/>
    <dbReference type="eggNOG" id="KOG4130">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="271604at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039731">
        <property type="entry name" value="Rce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046:SF0">
        <property type="entry name" value="CAAX PRENYL PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046">
        <property type="entry name" value="PROTEASE U48 CAAX PRENYL PROTEASE RCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="12">
        <location>
            <begin position="149"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH58875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="312" mass="33775" checksum="4878D85017ADCAC2" modified="2009-05-26" version="1">MGMRAIIDALKANGTYGVAQCLFITIAFVGGLYIWPPSPHPRDSPHTIKRRFLSLAMTLAMCWVPTYVCIRDEHSRGSRAANLAGTFHVLGLGRPDADAIDAVVDAVLSVACVMYLTAALFLGPLTHLALDGKLVSTFADAFRIDTVLKLRNYVVAPVSEEFAFRACMAPLLILCGRWSAPAARIFTPMRATWTCPVFFGLAHLHHFGEACARFGVLVAVVSVVAQFTYTVVFGWFAAFTLLRTGSIAGAMASHAFCNVVGFPDVEGAVAHERKAVVLAAYACGIALFTAGLWRVTDPDLHHASLWEEWSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP63</accession>
    <name>C1MP63_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GPX5</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_70210</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056765.1">
        <property type="nucleotide sequence ID" value="XM_003056719.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MP63"/>
    <dbReference type="GeneID" id="9682670"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70210"/>
    <dbReference type="eggNOG" id="KOG1651">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NGHEMPL"/>
    <dbReference type="OrthoDB" id="446890at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0711">Selenium</keyword>
    <keyword evidence="6" id="KW-0712">Selenocysteine</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="non-standard amino acid" description="Selenocysteine" evidence="6">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000303-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="157" mass="17223" checksum="A58D552842662CDC" modified="2009-05-26" version="1">MANFHSLSAKDIDGNDVDFAKFKGKVCLVTNVACKUGATRSNYQEMSAMAKELGPKGLEIICFPCNQFGRQEPGSNEEIKKFVEEKFDFSGPGVNMMDKIDVNGANTSPVWKWLKEQQPGDVSWNFAAKFIIDKDGNVVERNGSGAGDSKAKLTSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP65</accession>
    <name>C1MP65_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUMO-conjugating enzyme UBC9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_14889</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056766.1">
        <property type="nucleotide sequence ID" value="XM_003056720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP65"/>
    <dbReference type="STRING" id="564608.C1MP65"/>
    <dbReference type="GeneID" id="9682671"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14889"/>
    <dbReference type="eggNOG" id="KOG0424">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TWECGIP"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019787">
        <property type="term" value="F:ubiquitin-like protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000035">
        <property type="entry name" value="SUMO-conjugating enzyme ubc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="12">
        <location>
            <begin position="4"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH58411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="158" mass="18149" checksum="85A3C03F9A4AF7B4" modified="2009-05-26" version="1">MSGIARSRLMEERKVWRKDKPHGFYARPVTVGDGSVDILKWECQIPGKKDTDWHGGYYPLTMEFSEDYPSKPPKCKFPEKFFHPNIYPSGTVCLSILNEDDGWRPSITLKQILLGIQELLSTPNSASPAQSEAYMMFTTDEKQYKIRVRQQAAKYPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPG8</accession>
    <name>C1MPG8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Pyruvate kinase</fullName>
            <ecNumber evidence="5 15">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MICPUCDRAFT_49534</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 15"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057955.1">
        <property type="nucleotide sequence ID" value="XM_003057909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPG8"/>
    <dbReference type="STRING" id="564608.C1MPG8"/>
    <dbReference type="GeneID" id="9683068"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49534"/>
    <dbReference type="eggNOG" id="KOG2323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="17">
        <location>
            <begin position="129"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="18">
        <location>
            <begin position="494"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="10"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH57906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="665" mass="71042" checksum="0304747B8F10CC12" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPM3</accession>
    <name>C1MPM3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56958</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057979.1">
        <property type="nucleotide sequence ID" value="XM_003057933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPM3"/>
    <dbReference type="GeneID" id="9683417"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56958"/>
    <dbReference type="OrthoDB" id="10668933at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="204" mass="21077" checksum="576DE096F804E8A4" modified="2009-05-26" version="1">MGNASSTSAPSAAPAPNPPPSRPPKNPLERVFGPPRRDGPLRNPGWDDRVARTTAAGFFAGLAGGGALAAYRESIHYATIMANTSGNCAVVAGMFASGKEASRLVRQSDGDAIDAFVGGFAAGAVCASWWRDRRSALAGGLALGSLCGGIHWILDPASDASAPARALGFAVDDGGWMAPTWFPVVRSISHWFPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPU6</accession>
    <name>C1MPU6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57041</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057646.1">
        <property type="nucleotide sequence ID" value="XM_003057600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPU6"/>
    <dbReference type="GeneID" id="9683450"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57041"/>
    <dbReference type="OrthoDB" id="10644665at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="194"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="393"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="419"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="544" mass="59114" checksum="1C8A8812E6E8CF9C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ81</accession>
    <name>C1MQ81_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histone-lysine N-methyltransferase, H3 lysine-79 specific</fullName>
            <ecNumber evidence="1">2.1.1.360</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Histone H3-K79 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_57193</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60328"/>
            <dbReference type="Rhea" id="RHEA-COMP:15549"/>
            <dbReference type="Rhea" id="RHEA-COMP:15552"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.360"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.360" evidence="1"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057711.1">
        <property type="nucleotide sequence ID" value="XM_003057665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ81"/>
    <dbReference type="STRING" id="564608.C1MQ81"/>
    <dbReference type="GeneID" id="9683520"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57193"/>
    <dbReference type="eggNOG" id="ENOG502S1KF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CNCVTWD"/>
    <dbReference type="OrthoDB" id="496746at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140956">
        <property type="term" value="F:histone H3K79 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025789">
        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030445">
        <property type="entry name" value="H3-K79_meTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451:SF19">
        <property type="entry name" value="ACTIVATED IN BLOCKED UNFOLDED PROTEIN RESPONSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451">
        <property type="entry name" value="HISTONE H3 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08123">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOT1" evidence="6">
        <location>
            <begin position="113"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="281" mass="30367" checksum="D1E99358C8D68247" modified="2009-05-26" version="1">METATAPPPKKRSEAEILRSLLENGVAKRFDLVAWANAGCRQPTPIERLLHLFEQCRPDVAKLIVLEELEGTPEEDADVLVYGEIDTVEFTELLNKYGGVNALGGGGGDDGGRVFYDLGSGTGKAVCAAGLCAHFRHVRGVEILPCTAAIASVLVEDFVRDVLPGSRPAGNALVSVDVERGDFFAREHLERWRRADLVFCNCVTWDDDTMTTLSRHAEGLRPGAVFITVLCPLASDAFELVEEVELKFSWGSVEALVHRRLTDEQAAAAAALGAAMEAMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ99</accession>
    <name>C1MQ99_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_57211</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058090.1">
        <property type="nucleotide sequence ID" value="XM_003058044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ99"/>
    <dbReference type="GeneID" id="9683159"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57211"/>
    <dbReference type="OMA" id="CPAHCVG"/>
    <dbReference type="OrthoDB" id="442947at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="138"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="216"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="373" mass="39707" checksum="F56CAFD85AC2933B" modified="2009-05-26" version="1">MASLGFFGAGAVDVSDSSDSDAEEEPPREEAADATKADGAKDADDDGTAKKDDDDDADDDSKKPSSSGLPSFLEVMKNTEGVAPSFTREGAMLANDGKPLDARVAKVAANAHGGDRAGFAGFAGAKIPDGPLVASVDLGVTRVREIPPRVADRLYGDNGRGLTEMRLQTGARLTLPPPDDFRTEDEAPRRVIISGSIEAVNACVDEIEDMVRQDKLSMTKNVICPAHCVGTVIGAGGFSIKSIQKETGCVVKILGDFGRGGPMTDEQIRAMSSTQGGIDRYGVATDAPERVVTVKGPPKMVQKAVQMVQARIDMALRESGWVTRDSLKREREERAMFGKGAKKKAATTEYGDADEWEIPEENTAVEEVRDVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQS3</accession>
    <name>C1MQS3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_39393</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057807.1">
        <property type="nucleotide sequence ID" value="XM_003057761.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9683616"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39393"/>
    <dbReference type="OrthoDB" id="780650at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00538">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051216">
        <property type="entry name" value="Teneurin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11219">
        <property type="entry name" value="TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11219:SF69">
        <property type="entry name" value="TENEURIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 4" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912047" evidence="6">
        <location>
            <begin position="27"/>
            <end position="2070"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="2027"/>
            <end position="2048"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="1098"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="1357"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="1102"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="1122"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="1381"/>
            <end position="1390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2070" mass="214753" checksum="131329A98B94A7CA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRG0</accession>
    <name>C1MRG0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">phytol kinase</fullName>
            <ecNumber evidence="12">2.7.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_5805</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>phytol + CTP = phytyl phosphate + CDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38055"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17327"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:75483"/>
            <dbReference type="EC" id="2.7.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; tocopherol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.182" evidence="12"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057921.1">
        <property type="nucleotide sequence ID" value="XM_003057875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRG0"/>
    <dbReference type="STRING" id="564608.C1MRG0"/>
    <dbReference type="GeneID" id="9683739"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5805"/>
    <dbReference type="eggNOG" id="KOG4453">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SWPIFST"/>
    <dbReference type="OrthoDB" id="5673at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010276">
        <property type="term" value="F:phytol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039606">
        <property type="entry name" value="Phytol/farnesol_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32523:SF8">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32523">
        <property type="entry name" value="PHYTOL KINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00039024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH57872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="248" mass="25649" checksum="93B740429B1DEE96" modified="2009-05-26" version="1" fragment="single">VANLDAVLGDGTRRDAIAALAAAVGAYLWVKLFDVLASNDVLERKLSRKLIHTSCGPFFVLLWPLFSASPSAKYFAAAVPVLQGIRLMAIGVGAIENEDAIRAVSREGDRTELLRGPLYYTAVLVVCTAVFWRGSPSGIAALSLMCGGDGLADIVGRRLGKGNPLPFNADKSYAGSAAMFLGGFGLSLALCAFFHALGYMSVDPGSAAGRLALIAAACTAIEALPAGSFLDDNISVPVVAVVLGGVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRG2</accession>
    <name>C1MRG2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_39538</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057922.1">
        <property type="nucleotide sequence ID" value="XM_003057876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRG2"/>
    <dbReference type="GeneID" id="9683740"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39538"/>
    <dbReference type="OMA" id="YRDKPEI"/>
    <dbReference type="OrthoDB" id="495458at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNase-like" evidence="1">
        <location>
            <begin position="15"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="413" mass="46104" checksum="D5D41205120DE370" modified="2009-05-26" version="1">MADLFRGAIIRDCLVKCVVDGKTLKVLLNPLGWAPKPSGGWLARPTSATAPLRGPSEEDWEEVTVRLMCVDTEESSIPRGTSRHYKPITYGGREADAWLKEHLGVKHDGRPRPSAPISCDIEFDTTEPTIIGCRRHNEENYGRMLAYVHVGGRPVGENLSLAVVRAGRSPYFTKYGRSRLYHAEFLQAEQNAMSDETGLWGIMNAVGERSVPVSDYVRNYTQLLPWWSTREGIVEDFRRWQREGVARHVLVPRVHHEQLVKAAVDGETITVLVDLQPKDAFLMLGVMRNVEYADEQNRPRTGTVIHAGPKAFPFNLWLDHAFSEESEKIKALIERRYSRGGRNYAYVTGKAFMYRKKQIPQILVTRVSQFSDAPVKDAAALHHAGEKYHIAAASMPLEKHGPGVAAAAVGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRT3</accession>
    <name>C1MRT3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_63</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058928.1">
        <property type="nucleotide sequence ID" value="XM_003058882.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MRT3"/>
    <dbReference type="GeneID" id="9684004"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63"/>
    <dbReference type="eggNOG" id="KOG0952">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MCSATEF"/>
    <dbReference type="OrthoDB" id="5575at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000198">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000002">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000231">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000004">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000102">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000012">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000024">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000001">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000062">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF13">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="67"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="314"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="923"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="1131"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00055371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1741" mass="192928" checksum="E928B2E5B97CAF2B" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS77</accession>
    <name>C1MS77_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58377</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059001.1">
        <property type="nucleotide sequence ID" value="XM_003058955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS77"/>
    <dbReference type="STRING" id="564608.C1MS77"/>
    <dbReference type="GeneID" id="9684440"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58377"/>
    <dbReference type="OMA" id="WCMLLRV"/>
    <dbReference type="OrthoDB" id="17317at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34560">
        <property type="entry name" value="POLYKETIDE CYCLASE/DEHYDRASE/LIPID TRANSPORT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34560:SF1">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="488"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="501" mass="53890" checksum="1814CB2D7EE9FFC6" modified="2009-05-26" version="1">MAVEADAVARALELIDDDRLVAGARVLRAANISPSASASSSSSSDANLKLAASLRKASRVVDVVRSLKATPDERSGWLVQGEHMGKRDVSIYYRLDPETKTKLTARVESPIDESLLVPMIRRDFCERLSPPTPRFQSPPSTPFNSASDAYELHPDVIASYGTTLVSVLNESELYATWLPNWTVPRFRVRRSVKLSQSGRCSQVVLVTCDLPWPFSPRECVLDACGVDDIDHSGDIAVLVRSLDGLDDDDDDEREENDDDDAAAKASKRKTKKRAEGEFEAPPPDDKSVVRIGFHGGFLFRALPPGWKTYKRAKKDKKKDTKRASASAGASSGETDEGTDGGGWGWGMGSWGLGGGGDANDGGDGDDDVEPKITPGHLDDPDAEALLHAAEEDVLSNARVPAAAGDAGDGDGDGDGDGDGDAGGKKQLLVSVQMFIDPKLEYVPSSLMNFVVRTVTYTMWCMLLRVAEGIRDGKMPEHQTAIESKARPGRAFGPPARRAVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSA3</accession>
    <name>C1MSA3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TRX_2.1</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_68394</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059015.1">
        <property type="nucleotide sequence ID" value="XM_003058969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSA3"/>
    <dbReference type="GeneID" id="9684087"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68394"/>
    <dbReference type="eggNOG" id="KOG2501">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031397">
        <property type="term" value="P:negative regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030178">
        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472:SF1">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="74"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="427" mass="46054" checksum="C5D2B6EB68BF3515" modified="2009-05-26" version="1">MGCGASSASSSSVPSASSAPADTRWIENMFGKTLLTKSGERVATTKARDATRRFARPPSPPARIHHHHLTSVLPPPSRAAADVIIPPSLPPSLHPPRDVVRPQVLGGKIVAVYFGASWCGPCRAFLPTLTKISDALRSRGALFEVVYASSDNDDAEFAAHFTKGDKMPTWWFAHPSIGGAFAESRAWTEAMGDFGGAEVVKGVPHVSLFDASGKPMSGPYNACGLLQHRGVDGFPWAEPGYVRAAAENASELMALEKWKPALAAYEDVAELLKKNPNPADPSSLEDVAIALNDLAWIHNKLGSAKNALKVYEEALAAIVKDAKHLGTESEAYAVTLFNVADMKSEMKRFADAEKDLRVVSRLRAKILGKEDYEYGNTLYALAFVLENLGRHEESAGFYDDAADVMEKATGDAMDARKKADAMRAKCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSC3</accession>
    <name>C1MSC3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58432</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059028.1">
        <property type="nucleotide sequence ID" value="XM_003058982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSC3"/>
    <dbReference type="GeneID" id="9684467"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58432"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="207" mass="22477" checksum="E730D85A38B37ECA" modified="2009-05-26" version="1">MSAAPTHEPTLTEQEVRAPPRDASSAPTPSRVAAFLHSSPRRLNRTFKPARSLPPSLPPLQEPLIGAALRALYAAVRAKEDALDEAPKIPKDANTTTAKKLTTAHNTRLRDAFEPLSDVQLSAKALRAFKPRAEEIGVKAKNVEDACLLRVLITTASKKLLQKLDNKVEQKRKRQEKAAAAKEVAKVQKTAADVEGVNENEPMCAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSC9</accession>
    <name>C1MSC9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_58439</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059030.1">
        <property type="nucleotide sequence ID" value="XM_003058984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSC9"/>
    <dbReference type="STRING" id="564608.C1MSC9"/>
    <dbReference type="GeneID" id="9684098"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58439"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SFACFET"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="21"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="121"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="270"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="385"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="494"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="656"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="754" mass="77174" checksum="7DDE44FA6A6795DE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT01</accession>
    <name>C1MT01_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <ecNumber evidence="10">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_26764</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the IspH family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="10"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058771.1">
        <property type="nucleotide sequence ID" value="XM_003058725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT01"/>
    <dbReference type="STRING" id="564608.C1MT01"/>
    <dbReference type="GeneID" id="9683856"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26764"/>
    <dbReference type="eggNOG" id="ENOG502QPIQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NSAIWDS"/>
    <dbReference type="OrthoDB" id="1698201at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.20">
        <property type="entry name" value="4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009911">
        <property type="entry name" value="PRK13371.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31619">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31619:SF5">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="523" mass="57992" checksum="4737D27613C5730B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTA8</accession>
    <name>C1MTA8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_17419</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptotagmin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058833.1">
        <property type="nucleotide sequence ID" value="XM_003058787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTA8"/>
    <dbReference type="GeneID" id="9683894"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17419"/>
    <dbReference type="eggNOG" id="KOG1012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21677">
        <property type="entry name" value="SMP_SYT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045050">
        <property type="entry name" value="Synaptotagmin_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039010">
        <property type="entry name" value="Synaptotagmin_SMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10774:SF190">
        <property type="entry name" value="C2 CALCIUM_LIPID-BINDING ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10774">
        <property type="entry name" value="EXTENDED SYNAPTOTAGMIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17047">
        <property type="entry name" value="SMP_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="10" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="12">
        <location>
            <begin position="16"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH57288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="201" mass="22180" checksum="28D444ABD53E1CB0" modified="2009-05-26" version="1" fragment="single">MKVALQHLPKWTKQPDHSRTAWLNKSIDCFWPGLDTAASQCIRDSVEPMLRTMMPSFVNWIGFEKITLGPTPLVVGGAKTHGSNSEDAMLELEIAWTSGVDVILSAYVFGVRIPIRLHDVQLKTTVRLDFNPLVDELPCLGAVDVSLLDELALLDFGLTIPPGIDLMALPGVQQLVKHVVRGSLKTMTYPEKMSCPIMTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTY7</accession>
    <name>C1MTY7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino Acid/Auxin permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_58602</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059101.1">
        <property type="nucleotide sequence ID" value="XM_003059055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTY7"/>
    <dbReference type="STRING" id="564608.C1MTY7"/>
    <dbReference type="GeneID" id="9684551"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58602"/>
    <dbReference type="eggNOG" id="KOG1303">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AMTFFLP"/>
    <dbReference type="OrthoDB" id="498603at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="67"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="546" mass="58840" checksum="8B04E782F8360BA0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU59</accession>
    <name>C1MU59_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58677</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059437.1">
        <property type="nucleotide sequence ID" value="XM_003059391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU59"/>
    <dbReference type="GeneID" id="9684877"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58677"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="170" mass="19716" checksum="EA556FFA08FB537F" modified="2009-05-26" version="1">MWKIKEFTVRKLTTRYAATSFFRSSYEPVRKCACHIMTTKTTTFTTQKHRRFVWRCGVSAATGCLSGDVAAHRWSVERGRDRTGWVKSVRVYRTHLTKSKYTTVVRRMNTTAVFASSSTARLLLRHRLGRDGREDEGREKGMKRRGTGVGRRTREGNRPRARKDARGRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV86</accession>
    <name>C1MV86_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59094</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059329.1">
        <property type="nucleotide sequence ID" value="XM_003059283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV86"/>
    <dbReference type="GeneID" id="9685066"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59094"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="94" mass="9923" checksum="A90F4E426C29C25D" modified="2009-05-26" version="1">MSRNDGTANDGDGERPRYLSFKFTSGERSSALLERAAAWAFGCRAPPMIAPRPRLPGDAPIPRGVDLGALVAARSNARVEACGGHTEGGRDGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVB8</accession>
    <name>C1MVB8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59134</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059640.1">
        <property type="nucleotide sequence ID" value="XM_003059594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVB8"/>
    <dbReference type="STRING" id="564608.C1MVB8"/>
    <dbReference type="GeneID" id="9685080"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59134"/>
    <dbReference type="eggNOG" id="ENOG502QRWE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YSRAVSH"/>
    <dbReference type="OrthoDB" id="38730at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044">
        <property type="entry name" value="NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044:SF1">
        <property type="entry name" value="NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="273" mass="28903" checksum="ABBFAD4E226FB4E7" modified="2009-05-26" version="1">MASSSQSSSDGVMPSIIIGGGRVGQALFDMGVDGDVIVKRGDAFPSSPATGPIYVCTRNDALQGVVDATPEARRKDLVFLQNGMLQPWLDARGLGGNTQALVYFAVAKMNEKPTDGITDANPEGLTAANGEWADAFAARLRSGGLRCHVLDDDAFRASMFEKLIWICAFMGVGAAHPGATVGDVESAHKEEVEALIAELVAGSESAKGVRFAEGTIPRLAAYARAVSHFPTAVKEFEWRNGFFCGISERELAAGRLDPFPTHTALMKQVGALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVJ8</accession>
    <name>C1MVJ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59404</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059764.1">
        <property type="nucleotide sequence ID" value="XM_003059718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVJ8"/>
    <dbReference type="GeneID" id="9685489"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59404"/>
    <dbReference type="eggNOG" id="ENOG502S4BV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FKYKCRV"/>
    <dbReference type="OrthoDB" id="539593at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048469">
        <property type="entry name" value="YchJ-like_M"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17775">
        <property type="entry name" value="YchJ_M-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YchJ-like middle NTF2-like" evidence="2">
        <location>
            <begin position="131"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="256" mass="27616" checksum="D0982D00C184EDA6" modified="2009-05-26" version="1">MAAVRCAFLPATTKGVRCPNANLARARRDATTPRPVVVAPRRGGGDGNDHGGVDDGRRRRRGVGVVARGKKKKGFAELLGGEDEPVVVAKSKSSTELSASERCPCGGGAEGAPYARCCKPFHKNESYPDDCVTLMRSRFSAYAKGEGEYVVKTTHPENPIFRDGAKAESGKVVSSLAEDVRMTCKKVKFYGLEIVTDRAGKNAEEHMVGFKYKCRVVGQKGFKEGAEENHSELSTFRKGAEDGKWLFLDGITGAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVR2</accession>
    <name>C1MVR2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59473</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060083.1">
        <property type="nucleotide sequence ID" value="XM_003060037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVR2"/>
    <dbReference type="GeneID" id="9685235"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59473"/>
    <dbReference type="OMA" id="DEFFCAS"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912185" evidence="2">
        <location>
            <begin position="23"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="519" mass="54724" checksum="C335F9FF0E4725EB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWC1</accession>
    <name>C1MWC1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_4415</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059898.1">
        <property type="nucleotide sequence ID" value="XM_003059852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWC1"/>
    <dbReference type="STRING" id="564608.C1MWC1"/>
    <dbReference type="GeneID" id="9685628"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4415"/>
    <dbReference type="eggNOG" id="KOG2914">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GVIMEFE"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47108">
        <property type="entry name" value="5-AMINO-6-(5-PHOSPHO-D-RIBITYLAMINO)URACIL PHOSPHATASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47108:SF1">
        <property type="entry name" value="5-AMINO-6-(5-PHOSPHO-D-RIBITYLAMINO)URACIL PHOSPHATASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="287" mass="31740" checksum="FAF232A148CDDCBA" modified="2009-05-26" version="1" fragment="single">FPPVGVADDHTIANPLLRSQRLSTGWFGCVFELEGVLVNSREAEHREAWTKLAKERGERPPAELVLKYCDLMKPEAFIERQLRWTRDPMEVRRIRQRKGEIYDEILEEQKSLGGRGGGGGDGIGGGGGLDEFALRDGVLPFLNLLADAGVPMAAISNAYGYHDLCGVLSKIGILGYFEDANDGQGPHVVAADDVRDWLPDPEPLERACDLMQRTPKRTIVFGNNTTVTEACYEKGSKAVLLLGRQPRYEMQNADSVVEKLTDLTIANLKNLFADETSEAAEPERQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWY1</accession>
    <name>C1MWY1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_47661</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059710.1">
        <property type="nucleotide sequence ID" value="XM_003059664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWY1"/>
    <dbReference type="STRING" id="564608.C1MWY1"/>
    <dbReference type="GeneID" id="9685439"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47661"/>
    <dbReference type="eggNOG" id="ENOG502RXRB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YWIDWID"/>
    <dbReference type="OrthoDB" id="515493at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044818">
        <property type="entry name" value="ILR3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46133">
        <property type="entry name" value="BHLH TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46133:SF15">
        <property type="entry name" value="BHLH TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="96"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="144"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="277" mass="28934" checksum="2DD13E0E0D624008" modified="2009-05-26" version="1">MTSAPGANAGESIAPAGAVGVKKEETAVNKEDSGDWLADIFDAVDEDAITSLEMGDVALPQDILAKVDEGSASAVAAGKKEEGVGKRGRGEGGEELSKVKKSRREKLRREALNDRFMGLSALLDPSKPPATDKATIVTEAAAVISSLRKQLAELGENLEKLTASNEALETEKNALASDKASLMRDKVALQQEKHKLEHQLHVFMGSMPFASPPPGMMVMHHPPGAPPPGAAIVSSTASGAKVGGHPGGMMPMMWSFPPLVVQSTTAEEDAKLRAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX37</accession>
    <name>C1MX37_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_68991</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060623.1">
        <property type="nucleotide sequence ID" value="XM_003060577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX37"/>
    <dbReference type="STRING" id="564608.C1MX37"/>
    <dbReference type="GeneID" id="9686060"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68991"/>
    <dbReference type="eggNOG" id="KOG1947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CANLRTI"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055411">
        <property type="entry name" value="LRR_FXL15/At3g58940/PEG3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF190">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24758">
        <property type="entry name" value="LRR_At5g56370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box/LRR-repeat protein 15/At3g58940/PEG3-like LRR" evidence="3">
        <location>
            <begin position="328"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="514" mass="54808" checksum="D394AB33702F6DFA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX48</accession>
    <name>C1MX48_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_34549</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060629.1">
        <property type="nucleotide sequence ID" value="XM_003060583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX48"/>
    <dbReference type="STRING" id="564608.C1MX48"/>
    <dbReference type="GeneID" id="9686066"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34549"/>
    <dbReference type="eggNOG" id="KOG4300">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="APFMFIE"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052356">
        <property type="entry name" value="Thiol_S-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036:SF1">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="69"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="250" mass="26395" checksum="F147559430A232FA" modified="2009-05-26" version="1">MTAIVDADPVLLAEFDRQRNAKQDVLFAKGMNGGMGGYESAVAARKNDLFEDVFASLPKGSNVEATVVEVGMGTFPNARYYFDGGRRGGRKLDIVGVDPNDAMESFARSNLAKANEAFGGGGGEDASLRIVHGVAEALPLKDNSADAVVCTLTLCSVLDQVAAVSEIKRILKPGAPFMFIEHVLSEDDPRLAAQQISLNGMQVAMADGCHLDRKTLDVIDAAGFASVRSERFTLPGFGLISSQVAGIAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXZ9</accession>
    <name>C1MXZ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60346</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060785.1">
        <property type="nucleotide sequence ID" value="XM_003060739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXZ9"/>
    <dbReference type="STRING" id="564608.C1MXZ9"/>
    <dbReference type="GeneID" id="9685918"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60346"/>
    <dbReference type="eggNOG" id="KOG0715">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YRCAIND"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45286">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45286:SF1">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="41"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="530" mass="56713" checksum="09D9B925423EB945" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYQ5</accession>
    <name>C1MYQ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59988</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060610.1">
        <property type="nucleotide sequence ID" value="XM_003060564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYQ5"/>
    <dbReference type="STRING" id="564608.C1MYQ5"/>
    <dbReference type="GeneID" id="9685753"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59988"/>
    <dbReference type="eggNOG" id="KOG0620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2338">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WHELLFE"/>
    <dbReference type="OrthoDB" id="412787at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF37">
        <property type="entry name" value="2',5'-PHOSPHODIESTERASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="240"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="811" mass="86030" checksum="5541627E298084DF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ53</accession>
    <name>C1MZ53_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GDP-L-fucose synthase</fullName>
            <ecNumber evidence="3">1.1.1.271</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_60606</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.271" evidence="3"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060897.1">
        <property type="nucleotide sequence ID" value="XM_003060851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ53"/>
    <dbReference type="STRING" id="564608.C1MZ53"/>
    <dbReference type="GeneID" id="9686595"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60606"/>
    <dbReference type="eggNOG" id="KOG1431">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HPSNYGY"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="UniPathway" id="UPA00128">
        <property type="reaction ID" value="UER00191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050577">
        <property type="term" value="F:GDP-L-fucose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05239">
        <property type="entry name" value="GDP_FS_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00956">
        <property type="entry name" value="GDP_fucose_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028614">
        <property type="entry name" value="GDP_fucose/colitose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238:SF1">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="7">
        <location>
            <begin position="9"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="323" mass="36720" checksum="C25671884DFB67CB" modified="2009-05-26" version="1">MSSPEKTVVMVTGGSGLVGKAIQEVIEAEEGTLNERWVYLSSGDGDLTCPIQTSAIFDKYMPTHVIHLAAQVGGLFANMKYKVQFWRNNVIMNDNIFQECHKRNIKKLVSCLSTCIFPDKTTFPIDETMIHDGAPHFSNEGYAYAKRMVDVQNRMYRDQYGMKFTSVIPTNIFGKHDNFHLEDSHVIPGLIHRGYLCKQKGEPFQIWGTGKPLRQFIFSKDLARLMVWTLRSYDEADPIILSVGEEDEVSIADVAHTVAKALGFEGEIQFDATKADGQHKKTANNAKLRRYLPDFKFTPFEDAMKETVEWFTENYATPGRVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZY2</accession>
    <name>C1MZY2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_70223</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061299.1">
        <property type="nucleotide sequence ID" value="XM_003061253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZY2"/>
    <dbReference type="STRING" id="564608.C1MZY2"/>
    <dbReference type="GeneID" id="9686472"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70223"/>
    <dbReference type="eggNOG" id="ENOG502SBR7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1112980at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062064">
        <property type="term" value="F:box C/D methylation guide snoRNP complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027921">
        <property type="entry name" value="NOPCHAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28674:SF1">
        <property type="entry name" value="NOP PROTEIN CHAPERONE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28674">
        <property type="entry name" value="SIMILAR TO DNA SEGMENT, CHR 10, WAYNE STATE UNIVERSITY 102,-EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15370">
        <property type="entry name" value="NOPCHAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="176" mass="18055" checksum="BE1C52281886C9BD" modified="2009-05-26" version="1">MAGTNAAGCVPERSRELLAAEHAAPPSPLLVNAPKRSPGDPPATKPDFSAMPPPPTALLGKLSAFLPQMKAANDSLAEAMKTRPASEFDVECVDEEGGESHVAMDVGLGVVELNTEDAVAKATANAGFAVVENDDGGRAKVVDDDDDDDDEILIGAGAKRGRDGAAKKTPGIEVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N043</accession>
    <name>C1N043_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Central pair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PF16</name>
        <name evidence="1" type="ORF">MICPUCDRAFT_35126</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061330.1">
        <property type="nucleotide sequence ID" value="XM_003061284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N043"/>
    <dbReference type="STRING" id="564608.C1N043"/>
    <dbReference type="GeneID" id="9686502"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35126"/>
    <dbReference type="eggNOG" id="KOG0166">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CECIEQS"/>
    <dbReference type="OrthoDB" id="522946at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000196">
        <property type="entry name" value="Sperm associated antigen 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23314:SF0">
        <property type="entry name" value="SPERM-ASSOCIATED ANTIGEN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23314">
        <property type="entry name" value="SPERM-ASSOCIATED ANTIGEN 6 ARMADILLO REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="508" mass="54389" checksum="8D33A81ACFC9358E" modified="2009-05-26" version="1">MAATRAVLQVFEKYQKDRVAFVQTVAELATRPQNVEPMQSAGVMALLRPLLLDNVPSIQQSAAIALGRLANYSDHLAEAVVSNEILPQLVYSLSEQNRFYKQAAAFVLRAVAKHSPPLAQAVVDSGALDSLVQCLEEFDPGVKESAAWALGYVAGHNADLAATVVEAGAVPLLVLCVQEPELSLKRIAASSLSDIAKHTPEMAQAVVDAGAIAYLAPLIVSPDAKLKRQVCAALGQVAKHSVDLAEVVVEAEIFPNILMCLKDVDGFVRKHAATCIREVAKHTPELAQLIVSNGGVGALVDYVHESESNNRLPGIMALGYVAAFSETLATAVIASKGIAPLYAALVEEPEDHIKSASAWSLGQIGRHTPDHAKAVADAGALSKLVAVGANPRSSDDLKTKCVRSLRFIIEKLTDLRALDKTLQNRELPHEIVRYVVHQISKVLPNDPQGRHDFVVGGGLAACQALDAEAGTALKEYVDIIKSCYPEEIVQYYSPTYATQLLEKLEVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N054</accession>
    <name>C1N054_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_20089</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061069.1">
        <property type="nucleotide sequence ID" value="XM_003061023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N054"/>
    <dbReference type="STRING" id="564608.C1N054"/>
    <dbReference type="GeneID" id="9686774"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20089"/>
    <dbReference type="eggNOG" id="KOG3275">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GQNWPQK"/>
    <dbReference type="OrthoDB" id="672793at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047627">
        <property type="term" value="F:adenylylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01277">
        <property type="entry name" value="HINT_subgroup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039384">
        <property type="entry name" value="HINT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648:SF1">
        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="HIT FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="12"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="2 3">
        <location>
            <begin position="105"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="148" mass="15649" checksum="C503D948FA855F22" modified="2009-05-26" version="1">MASSIPYDDDNVFKKIIEGVIPCYKIFETEHALAFLDAFPMAPGHALLVPKTTGAATMMDLPEDVAANVLKELPRLARAVKAATGCDGVNVVQNNGATAGQVVFHLHVHVIPRWEKDGVVRLGKSGEAIGKDAADAMVAKMKAAIGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0G4</accession>
    <name>C1N0G4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_28543</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Membrane</location>
            <topology evidence="2 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PRA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061635.1">
        <property type="nucleotide sequence ID" value="XM_003061589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0G4"/>
    <dbReference type="STRING" id="564608.C1N0G4"/>
    <dbReference type="GeneID" id="9686825"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_28543"/>
    <dbReference type="eggNOG" id="KOG3142">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MQKNLNY"/>
    <dbReference type="OrthoDB" id="63113at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004895">
        <property type="entry name" value="Prenylated_rab_accept_PRA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317:SF0">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03208">
        <property type="entry name" value="PRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="190" mass="20571" checksum="597F66B8A007BE9E" modified="2009-05-26" version="1">MAEVTQTTGSPFMAALGKIKETTMHVVGQRKPMSEILDRTAYQRPASFSEATGRMQKNLNYFKINYILFTAVVLAAFIMYHPSSLVMLGAISAAWGYVYMVRTEPLKIGERPVSDREKFLGMSGASILAVFFMSSAGSVMLSAMGVALLCIGAHSAVRVPDDLFIDDSANENGFFSFLQPPRPGLTGGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0Z0</accession>
    <name>C1N0Z0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Origin recognition complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_62973</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061717.1">
        <property type="nucleotide sequence ID" value="XM_003061671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0Z0"/>
    <dbReference type="STRING" id="564608.C1N0Z0"/>
    <dbReference type="GeneID" id="9686920"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62973"/>
    <dbReference type="eggNOG" id="KOG2228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DERIGMQ"/>
    <dbReference type="OrthoDB" id="343623at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016527">
        <property type="entry name" value="ORC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032705">
        <property type="entry name" value="ORC4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14629">
        <property type="entry name" value="ORC4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="237"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="646" mass="69231" checksum="C903465ED62DD4A0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N161</accession>
    <name>C1N161_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_41685</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061513.1">
        <property type="nucleotide sequence ID" value="XM_003061467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N161"/>
    <dbReference type="STRING" id="564608.C1N161"/>
    <dbReference type="GeneID" id="9687194"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41685"/>
    <dbReference type="eggNOG" id="KOG2265">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="416217at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF3">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="112"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="256" mass="27576" checksum="7A54357235720296" modified="2009-05-26" version="1">MASSERASSSTARVALALAAGGVAAYAYYRLSRALAVARARDEDPSIAADVMDAARASTARDRETFASQSEEETAEMRRQAAVHMARLQAAGNMGQDGAGGMKNLTAEECGGVTDRYRWKQTEREIVLEFPIPRGVTSKHVDVRIETKTLKVAIRPCPAAEIATERVVIAGRLLRDVVPDECVWEIEAADDGDGGRKVVVTLFKLLATMAMHHWNCVVKGEPTIDVKKFGPAIVGINGNDPSALQRMMEGLPPPGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1L1</accession>
    <name>C1N1L1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_20175</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061576.1">
        <property type="nucleotide sequence ID" value="XM_003061530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1L1"/>
    <dbReference type="STRING" id="564608.C1N1L1"/>
    <dbReference type="GeneID" id="9687281"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20175"/>
    <dbReference type="eggNOG" id="KOG1612">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YNTRIPK"/>
    <dbReference type="OrthoDB" id="272245at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11367">
        <property type="entry name" value="RNase_PH_RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="29"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="213"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="318" mass="33062" checksum="855DBDEE5951A863" modified="2009-05-26" version="1">MPLSRAEIDYVRDGIDQNMRNDGRTREDYRELTLDLGVIPQATGSARARLGLDAWSTDVIVTVKADIGAPSAEHPGDGRLRCAVELSSASDTAYGGRGGEARATELSRALERSLLGATAGSSASLSAHGEGCALDMSALGIQRGKSCWILQVDGLVLADDGNVLDALSMATRAALFDAKIPKVTAVAGPNPDDPAELELDDDPEECSRLDVSGVPVIVTLTRVGKHSIVDATKDEESMRDPRLCVGVDATGKVRSVGKRGGGGIDLNAMCAMTRTACECGKQLIAALDEAHAKAEADAAVQAAKGDDDDDDADDAMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1Q9</accession>
    <name>C1N1Q9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Patatin</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_3862</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Lipolytic acyl hydrolase (LAH).</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the patatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062161.1">
        <property type="nucleotide sequence ID" value="XM_003062115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1Q9"/>
    <dbReference type="STRING" id="564608.C1N1Q9"/>
    <dbReference type="GeneID" id="9687600"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3862"/>
    <dbReference type="eggNOG" id="KOG2214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MRPFELL"/>
    <dbReference type="OrthoDB" id="15478at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF29">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE SWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4 5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="6">
        <location>
            <begin position="5"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="36"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="336" mass="37230" checksum="D483F291DE39DC7C" modified="2009-05-26" version="1" fragment="single">GRTALCLSGGGALAMYHFGVIKVLLQEGLLPQVISGTSGGSIVAAFISMFPEEELLKTIRPDLSSRHGVRWFPPVWKMVINFVQNSVLMSSENFAETTRAYFGDVTFAEAFVISKRAVSIQISVGSGHGFVLNHFTAPQVVIRTAVNASCALPGLMRPFELLAKDEKTGELIAFHPPGVSSFDGTITADIPAARLTELFNCNNFIVSQVNPHVNFVLHLAEEGQGRRLSRAARSNDRRAAVIKLLRVAKYLLLNIKYGVQKLLEVDLLNLRMVRTLQGILVQDFRGHITVLPQLQFRDYLRVLRHPNDDEMARFIRNGEAATWPHVEAIRLTMAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2K6</accession>
    <name>C1N2K6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_21172</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.107" evidence="1"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061890.1">
        <property type="nucleotide sequence ID" value="XM_003061844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2K6"/>
    <dbReference type="STRING" id="564608.C1N2K6"/>
    <dbReference type="GeneID" id="9687543"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21172"/>
    <dbReference type="eggNOG" id="KOG1527">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VIYMGIL"/>
    <dbReference type="OrthoDB" id="508204at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000001">
        <property type="entry name" value="Siroheme synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050161">
        <property type="entry name" value="Siro_Cobalamin_biosynth"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790:SF3">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790">
        <property type="entry name" value="SIROHEME SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="7">
        <location>
            <begin position="50"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="292" mass="31276" checksum="290CB0EEDE7DE0F6" modified="2009-05-26" version="1">MASASVAPPPRRFFHSPTPRRRRPRAGGGARASTRAPPSSSSSSSSSGFVHLVGAGPGGMDDMTTRALRLVRECDVLVYDDLGASERDVLAEARADAERIYVGKRGGRRSSWKQPDIDALLVDKCVAGKRVVRLKGGCPSTFSRVHSERAALRKRGCAHELVPGVSSALAAPLSAGIPLTHVDHGKHYVVCSAHDPDGIDFHAFNGIDTCVFLMVGKSLPVVCERLARDAGKRSDAPAAVIKNGRTREEEVFRGTLGTMAEVTAGRNLSPCVLVVGEVAREEEEEEEEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2L4</accession>
    <name>C1N2L4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51576</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061895.1">
        <property type="nucleotide sequence ID" value="XM_003061849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2L4"/>
    <dbReference type="STRING" id="564608.C1N2L4"/>
    <dbReference type="GeneID" id="9687546"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51576"/>
    <dbReference type="eggNOG" id="ENOG502QQ86">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GHINICS"/>
    <dbReference type="OrthoDB" id="2161379at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45296">
        <property type="entry name" value="TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45296:SF1">
        <property type="entry name" value="TRANSDUCIN_WD40 REPEAT-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="461" mass="45654" checksum="BCF392551DE0BC66" modified="2009-05-26" version="1">MQKTRALAAPKEMRVGSLLCAALSPHDDGATIVVGGERATALVFDLRAPSSRVTAHALSASTGCFDADDAVNAVAFNPTRPHALYCASGARVDAWDLRALPSTTTTTRSKSKSKSTSPSSGGGGSALGSPLHRYAFNADEINSIVIDAKGGAMACADDAGEVVAVDVSSPSSVDGKLLKRLRVGGHSNIASGACFREHKPWDVVSGGLDCAIVKWDRSRASAVASWRVSDLAAEDDAAAAADDDDDAAAAAASTSNAMNPPMVHAVAVASAVECGAALDPRARRLVAAACGDGTVALVDVDLPAAAARGAGGGKGKSKRGGAGGGGDASGGNGGGAFGGARRAVFLGRRGGGHASACTAVRFPGRFDGARVLSGGNDGVVKLWDWRVAAGMADSGADSGADAGADAAPAPPAATGLVCETAHGRKVNALTCRGADAGGGGGGDWLFVCDTSSRLSAYALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2P3</accession>
    <name>C1N2P3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_51608</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062122.1">
        <property type="nucleotide sequence ID" value="XM_003062076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2P3"/>
    <dbReference type="STRING" id="564608.C1N2P3"/>
    <dbReference type="GeneID" id="9687349"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51608"/>
    <dbReference type="eggNOG" id="KOG1552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NCYEYLY"/>
    <dbReference type="OrthoDB" id="446723at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="306" mass="33350" checksum="79B5EA933BA0A428" modified="2009-05-26" version="1">MSSLWKSIDPVDSIIFPGARMKSTYDEDGTPFAGELVIGDVVYKTLLLSLPCLVPGGLCSPPVHATAPCLVVLRLDATRPEGPCKGRGVIVYAHGNAVDIGAVAEEAKAMSHHLHCHVIVPEYPGYGVAKGKPCEDTVDVAVYAAVRLATEVIGAPIERVVMYGRSIGTGPIAAASARLDMMARSRPAAMILQSPFTSINDFARERAGRLLAWLFVSERWKTRVNLTRVQTPTLLIHGDEDKVISIEHSRQLRRITSFAAKPCELHVQKGRGHNDFDFVLDVLKPAGEFLRRVRSHTGPHTTAFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2Q3</accession>
    <name>C1N2Q3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_48381</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062126.1">
        <property type="nucleotide sequence ID" value="XM_003062080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2Q3"/>
    <dbReference type="STRING" id="564608.C1N2Q3"/>
    <dbReference type="GeneID" id="9687355"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48381"/>
    <dbReference type="OMA" id="IWYASRI"/>
    <dbReference type="OrthoDB" id="2212170at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="146" mass="16024" checksum="BDE00EFEF54A75B0" modified="2009-05-26" version="1">MSEEKTYTGRCYCGAVKVTAVGEPAAVAVCHCRDCSRWGGINMASLWPCEKVTVEGDLVEFTNPPPEGKPKGSNRKTCAKCRSNVLNDHPDTMKLTDVVSGIMDGYEFKPKMHINYSEAIWKVKDGLPKFATMPAAFGGDDKMLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2W4</accession>
    <name>C1N2W4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_48485</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062276.1">
        <property type="nucleotide sequence ID" value="XM_003062230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2W4"/>
    <dbReference type="STRING" id="564608.C1N2W4"/>
    <dbReference type="GeneID" id="9687944"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48485"/>
    <dbReference type="eggNOG" id="KOG3291">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QAEDAVW"/>
    <dbReference type="OrthoDB" id="10264639at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003106">
        <property type="entry name" value="PRK04027.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="33"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="194" mass="21680" checksum="9EAF5753B691F0E9" modified="2009-05-26" version="1">MAEVSEIKLFGKWTYDDVEINDISLEDYIGVKSKHAVYVPHTAGRYAQKRFRKAQCPIVERLVNALMMHGRNNGKKLMAVRIVKHTMDIIHLLSDQNPIQVIVDAIINAGPREDATRVGSAGVIRRQAVDISPLRRVNQAIYLITTGAREAAFRNVKTIAECLADELINAAKGSSNSYAIKKKDELERVAKANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2X9</accession>
    <name>C1N2X9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitochondrial-targeted muts 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MSH1</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_51959</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062284.1">
        <property type="nucleotide sequence ID" value="XM_003062238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2X9"/>
    <dbReference type="STRING" id="564608.C1N2X9"/>
    <dbReference type="GeneID" id="9687724"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51959"/>
    <dbReference type="eggNOG" id="KOG0217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LMGSITC"/>
    <dbReference type="OrthoDB" id="10252754at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053276">
        <property type="entry name" value="MtDNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48448">
        <property type="entry name" value="MUTL PROTEIN ISOFORM 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48448:SF1">
        <property type="entry name" value="MUTL PROTEIN ISOFORM 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="6">
        <location>
            <begin position="887"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="83"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1088"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1089"/>
            <end position="1098"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1258" mass="131567" checksum="B82AE3004E136379" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N358</accession>
    <name>C1N358_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48520</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062322.1">
        <property type="nucleotide sequence ID" value="XM_003062276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N358"/>
    <dbReference type="GeneID" id="9687992"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48520"/>
    <dbReference type="OMA" id="AESRYHA"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="418" mass="44660" checksum="379A1A49850AF52D" modified="2009-05-26" version="1">MGSGGIGKKKQADVPADGGIDKVRLVYVELVHNNAPFEELFQIDFGGWRAFFRAVKDFAEDPTSALSECIATGILQKNGIAFKDWGKKVRERSPAFKEQFNRFIHLPAVRYALATDLGMDPAATDLTDADGRSGPGGPSMNPAAIRDRDRYEPANDSYDERAGAGGSQQPRRPYSPSEGGYTANADSSMPAESRYHARKRADPDSPTSPMLDRLEMLLSSSPVDGPDSPIERLQRTLDEKDPEPPRGTAALGAGPATARRQFAGAGYAAMAARSPPPPPTTTTGGGALDVDTALAAATVTSPNGSVGGGVRNVSTPGVPGNLVQVDVSDTHVTVEFHRRRVSAYLAGFKNLLLNLRDHISSIERADVMHVARTVEETNARLDVAMEKIDQMTAAEEATHPGREEVDGYAASELDAYSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3I7</accession>
    <name>C1N3I7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_52189</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062620.1">
        <property type="nucleotide sequence ID" value="XM_003062574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3I7"/>
    <dbReference type="STRING" id="564608.C1N3I7"/>
    <dbReference type="GeneID" id="9688060"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52189"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="313"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="68"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="409" mass="43548" checksum="5C9D9F0232B3C1CB" modified="2009-05-26" version="1">MTDVVIVATAEDAAAGLGFIRTSRGVLRCMRCHTCRNPGLKKRCVNAPALDDAGGSVGGGIGDDARARAHAAAAPKSTKPRGGGNAAWAWQREDDGSWRRAAALAEEETAPPPSAEKSENPRTPSAADEPEPAARADAGAGEEEDAEDAEEKPVPDERPVVLLFTTPSGRANLGELPLVDALTHPDATCCAPDHRSSYLGGARGGGDLLRLVHATAQSLTRKRPFAFTAGLGLDGDDDRVAGGVMNQTRKTAAFSAAADDGSRLPGPGDGAAAEREIYEGEGAHACDEPGCGKTFHSVAKLRRHQLTHGDRAYRCSLPGCDKRFLDFAKLKRHWFSHEGADARPHLCPHPECGHAAANREQWRDHQLEAHADAERKPRAGFLCVYAGCGKRSGALERHEEHVRSCVYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3L2</accession>
    <name>C1N3L2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52216</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062635.1">
        <property type="nucleotide sequence ID" value="XM_003062589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3L2"/>
    <dbReference type="GeneID" id="9688075"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52216"/>
    <dbReference type="OMA" id="ESRIVEC"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="830"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1007"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="849"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1007"/>
            <end position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1265" mass="134328" checksum="73362EB67B166E98" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3W6</accession>
    <name>C1N3W6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52323</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062446.1">
        <property type="nucleotide sequence ID" value="XM_003062400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3W6"/>
    <dbReference type="STRING" id="564608.C1N3W6"/>
    <dbReference type="GeneID" id="9687886"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52323"/>
    <dbReference type="eggNOG" id="KOG3035">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VIWPKVI"/>
    <dbReference type="OrthoDB" id="671439at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01838">
        <property type="entry name" value="Isoamyl_acetate_hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045136">
        <property type="entry name" value="Iah1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209:SF19">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="12"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="279" mass="30217" checksum="130872339A9EFB01" modified="2009-05-26" version="1">MGLTDRRRAIVIFGDSLTQRSFQPAGWGAALAMRYQRRVDVINRGYGGYNSRWCLAMVDELFPASARGRDKPLLVTVMLGTNDAALPEVEPAPTVPLEEYRSNLDAIVAKLKQRAEHVVVMTPPCMDEPGRLAYQRETYQDDAVGRLERTNANTRRYADAAMAVAMLHGVPCVDLFASTSDALESAAASTDGPTTLFDDGIHFNALGQEVVYASLVRVIESAPGLEDLDPEKMPPDWPFGPDLRANPDANAGEAAAAASRRRGRAWTGRARGGGSSPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4N8</accession>
    <name>C1N4N8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_21783</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063030.1">
        <property type="nucleotide sequence ID" value="XM_003062984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4N8"/>
    <dbReference type="STRING" id="564608.C1N4N8"/>
    <dbReference type="GeneID" id="9688264"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21783"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053241">
        <property type="entry name" value="NADPH_pterin_aldehyde_rdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45267">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45267:SF2">
        <property type="entry name" value="NADPH-DEPENDENT PTERIN ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="161" mass="17037" checksum="FBF4BFD6DE6D8D8B" modified="2009-05-26" version="1" fragment="single">RPARLWETRATDWSRLLNDAKGVAVVLRRFLPSMVARGSGAIVNVTHVLDPPQGANVASYQASRAAISALTRCVAAELPPGMHAVEIDPGALLGLRGTEKEGADVGPTRRPGFDETACDWARAAVPFVLGLTREVNGCSVHVPGWGSLGGDVHAPHHRVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4Q1</accession>
    <name>C1N4Q1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hep hag like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_42460</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062830.1">
        <property type="nucleotide sequence ID" value="XM_003062784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4Q1"/>
    <dbReference type="STRING" id="564608.C1N4Q1"/>
    <dbReference type="GeneID" id="9688270"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42460"/>
    <dbReference type="eggNOG" id="ENOG502S7B0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTWTEYS"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12820">
        <property type="entry name" value="LbR_YadA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="entry name" value="Serralysin-like metalloprotease, C-terminal"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008640">
        <property type="entry name" value="Adhesin_Head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05658">
        <property type="entry name" value="YadA_head"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="Adhesin YadA, collagen-binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trimeric autotransporter adhesin YadA-like head" evidence="2">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Trimeric autotransporter adhesin YadA-like head" evidence="2">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Trimeric autotransporter adhesin YadA-like head" evidence="2">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Trimeric autotransporter adhesin YadA-like head" evidence="2">
        <location>
            <begin position="498"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Trimeric autotransporter adhesin YadA-like head" evidence="2">
        <location>
            <begin position="557"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Trimeric autotransporter adhesin YadA-like head" evidence="2">
        <location>
            <begin position="599"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Trimeric autotransporter adhesin YadA-like head" evidence="2">
        <location>
            <begin position="627"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="Trimeric autotransporter adhesin YadA-like head" evidence="2">
        <location>
            <begin position="659"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="742"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="888"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="747"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="888"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="917"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="940"/>
            <end position="953"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="960" mass="92784" checksum="40056249B6F48263" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N531</accession>
    <name>C1N531_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pyruvate dehydrogenase (acetyl-transferring)</fullName>
            <ecNumber evidence="3">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_22101</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Tetramer of 2 alpha and 2 beta subunits.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="3"/>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062902.1">
        <property type="nucleotide sequence ID" value="XM_003062856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N531"/>
    <dbReference type="STRING" id="564608.C1N531"/>
    <dbReference type="GeneID" id="9688535"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22101"/>
    <dbReference type="eggNOG" id="KOG0225">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LGYEMPC"/>
    <dbReference type="OrthoDB" id="10256198at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02000">
        <property type="entry name" value="TPP_E1_PDC_ADC_BCADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000013">
        <property type="entry name" value="Pyruvate dehydrogenase E1 component subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050642">
        <property type="entry name" value="PDH_E1_Alpha_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF60">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Dehydrogenase E1 component" evidence="8">
        <location>
            <begin position="36"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="386" mass="42653" checksum="DBE80A9C03F32187" modified="2009-05-26" version="1">MMIDVPIPFVAHRIDPPSQTVETSKAEIVDMFTQSYLMRRLEIAADVLYKGKFIRGFCHLYDGQARSISHWSPYDREAVCVGMEAALNKDDAIVTSYRDHCTHLGRGGTPLEVMAELMGRIDGASKGMGGSMHMYKRDAHFFGGNGIVGAQASSDWSPYDRTPIGAGLAFAMQYEKKPNVAVAMYGDGAANQGQLFEALNIAALWDLPLIYVCENNHYGMGTAIAKSAKSPEYFKRGDYVPGLKVDGMDALAVKQAIKFAKEHCVSGKGPIVLEMDTYRYHGHSMSDPGSTYRTRDEITGIRQERDPVERLRKLIVEHELLDTAEIKAIEKAQRKIVDEAVAAGKASPEPPVENLMKNMNQIMDNVVVRGVDSEARTHLTEAYGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5C7</accession>
    <name>C1N5C7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52894</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063148.1">
        <property type="nucleotide sequence ID" value="XM_003063102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5C7"/>
    <dbReference type="STRING" id="564608.C1N5C7"/>
    <dbReference type="GeneID" id="9688385"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52894"/>
    <dbReference type="eggNOG" id="ENOG502QQU0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FVHQMAT"/>
    <dbReference type="OrthoDB" id="10028886at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19368">
        <property type="entry name" value="TenA_C_AtTH2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050967">
        <property type="entry name" value="Thiamine_Salvage_TenA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43198">
        <property type="entry name" value="BIFUNCTIONAL TH2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43198:SF2">
        <property type="entry name" value="SI:CH1073-67J19.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiaminase-2/PQQC" evidence="1">
        <location>
            <begin position="32"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="218" mass="23850" checksum="FA8FE14DBE83F59B" modified="2009-05-26" version="1">MAPSETPPTAARRLFDHPSVRANYADMTAASSFVSQMANGTLPRAKYVAFLSQDRYFLFHFNRAYASALARAPGIEQQRTFHALIGGVLDELKLHEDACARWGVDDGALETIHPASRAYVDFLTALQSPDVPMDELVAGMTPCMRLYAALGRDYLDRGLVAEGCAYREWFDAYGGDEMGALAASLEALLPEDIVAGGGVEANYMRAMELERDFFAAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5H6</accession>
    <name>C1N5H6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52924</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063364.1">
        <property type="nucleotide sequence ID" value="XM_003063318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5H6"/>
    <dbReference type="GeneID" id="9688597"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52924"/>
    <dbReference type="OMA" id="ANDRPWH"/>
    <dbReference type="OrthoDB" id="46257at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.30">
        <property type="entry name" value="Hypothetical protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="200" mass="21432" checksum="3D5555F86E86A9E0" modified="2009-05-26" version="1">MKQPWADLVVSGAKTMETRAYALPPRLLGKPVALLRTPAAKDGEARSISHRSPYDRVGVPANVSSLGDACDPGAATIVALVTFTSVKEWDSAKDWAADGDKHLVPSDDEAFRWRRGDGLRRRVRGWIVGDVAPIAPTPSPKMTRALRSLFKLEFTADELLVKGIDDRGGGGGGGAVGDDDEEDDDAGIFADDGANDRPWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6C8</accession>
    <name>C1N6C8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53240</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063316.1">
        <property type="nucleotide sequence ID" value="XM_003063270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6C8"/>
    <dbReference type="GeneID" id="9688949"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53240"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="435" mass="47564" checksum="15D8179F6B191185" modified="2009-05-26" version="1">MAPRTPSIASRASARADALESLCALSAERERRRRRELDDARATRPRDDDDDASDAPSARPSSPPPLRLPARTPPRVHTYTIDDVRDAALEHRVDAERRALAAIRAAEALSKSNFVPERSWVARVGPVVRRCVASWRARARRANPTAAAAMEASRRASTIARPLGEDDASESRCVMVSHDLASIARALRDPSTIRCAHVGEDANDDGGWYSKDVTGRYEFPAVVRIARLSTPGAPMLAKHVTCARCRDVARDRRSATKTRCVACRTLVPSAVLVENANRRNREMRTDATTGPTCLFCETLRRRGRRRGDDGDGGERTKRINTIAAHPRAAGTFRAAHPFARADDAPPVEVLRALQRASAGAESTASVWDPISRQCRSVETERRWILPEDGGDVAKAVERARGGFGGGARGEEAFAREFLRLPGEPPSARRRAARAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6R9</accession>
    <name>C1N6R9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_36528</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063780.1">
        <property type="nucleotide sequence ID" value="XM_003063734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6R9"/>
    <dbReference type="STRING" id="564608.C1N6R9"/>
    <dbReference type="GeneID" id="9689042"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36528"/>
    <dbReference type="eggNOG" id="KOG1426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TWGANNE"/>
    <dbReference type="OrthoDB" id="512027at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="52"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="107"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="344" mass="36718" checksum="8A80704F27F47F92" modified="2009-05-26" version="1" fragment="single">MGQLGLGVRNAEDTTLRFVPTLLELYNGNGQKQPVIDVALGLEHTVAVVKGGRVFVWGSNRWGQLGIDQDPDVVPWTSIPTPIDIGGESIRNVSSAGGHNAALTFGGAVYTWGANNEGQLGQSGCIREDGIGNDPSVAGNPVIIEIKTGSYHSLALTDDGNLFSWGDNFFGQLGHGYLSLQQEPDAFYQTQNYRVPEMIDVPERVKHWDYGTTEVVTETVGNVTREVTRNVQVTGKIRLPDGGEDRIIQVDAGFFQSIALTKNGNVYVWGTNAKGQMGTCGCGPCVHDYDAAGQCDPLVGAPPLPPAPVAITFGAATPVVTNQETSTSNTTADPYANYFWNVGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6S6</accession>
    <name>C1N6S6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_53422</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063783.1">
        <property type="nucleotide sequence ID" value="XM_003063737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6S6"/>
    <dbReference type="STRING" id="564608.C1N6S6"/>
    <dbReference type="GeneID" id="9689046"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53422"/>
    <dbReference type="eggNOG" id="KOG3764">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RLNFEWA"/>
    <dbReference type="OrthoDB" id="497880at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF26">
        <property type="entry name" value="MFS-TYPE TRANSPORTER SLC18B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="67"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="512" mass="54267" checksum="6BD2F47625824539" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N723</accession>
    <name>C1N723_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL11c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">50S ribosomal protein L11, chloroplastic</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">CL11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_29915</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063828.1">
        <property type="nucleotide sequence ID" value="XM_003063782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N723"/>
    <dbReference type="STRING" id="564608.C1N723"/>
    <dbReference type="GeneID" id="9689098"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29915"/>
    <dbReference type="eggNOG" id="KOG3257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CKQFNAK"/>
    <dbReference type="OrthoDB" id="1091498at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000001">
        <property type="entry name" value="50S ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_uL11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="11">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="10">
        <location>
            <begin position="71"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00068991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00082752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH52201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="160" mass="17028" checksum="FB7623663C1C7FB9" modified="2009-05-26" version="1">MAAKIAGYIKLAIEAGKANPAPPIGPALGAKGVNIMMFCKEYNARTQDQAGTIIPVEITVFEDKSFTFVLKTPPASVLLKKAAGVAKGSAQLEKVGSITRDQLEEIAKIKMPDLNAHKVESAMRVVAGTAANMGITIEGWDMEESKEILRQEKAATWGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>C1N725</accession>
    <name>C1N725_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA replication licensing factor MCM4</fullName>
            <ecNumber evidence="13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_36602</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="function">
        <text evidence="11">Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="13"/>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063657.1">
        <property type="nucleotide sequence ID" value="XM_003063611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N725"/>
    <dbReference type="STRING" id="564608.C1N725"/>
    <dbReference type="GeneID" id="9689271"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36602"/>
    <dbReference type="eggNOG" id="KOG0478">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AFFKCNV"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000347">
        <property type="term" value="C:THO complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000217">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="356"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH52030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="764" mass="84620" checksum="579FA77BBD067854" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N764</accession>
    <name>C1N764_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43030</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063680.1">
        <property type="nucleotide sequence ID" value="XM_003063634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N764"/>
    <dbReference type="GeneID" id="9689121"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43030"/>
    <dbReference type="OMA" id="MYSNMAS"/>
    <dbReference type="OrthoDB" id="205639at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="497"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="635"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="381"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="339"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="352"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="552"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="645"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="655" mass="66608" checksum="A25D36F24523115A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7A3</accession>
    <name>C1N7A3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53613</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the p23/wos2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063702.1">
        <property type="nucleotide sequence ID" value="XM_003063656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7A3"/>
    <dbReference type="STRING" id="564608.C1N7A3"/>
    <dbReference type="GeneID" id="9689304"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53613"/>
    <dbReference type="OrthoDB" id="1564555at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06465">
        <property type="entry name" value="p23_hB-ind1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045250">
        <property type="entry name" value="p23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932:SF1">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DAF-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="2">
        <location>
            <begin position="5"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="235" mass="26585" checksum="F50C35BF9B3547EA" modified="2009-05-26" version="1">MTVTTRTPVVLWAQRKDRLFLTIDLHDATAPVVELSDDGVLKMTTTAGAPGVEGRHEYHLELEFLHPIDAKASKISVAPRQIVVMVMKTEEVGRRPLDDSFVRSFVVFPSLLFSFLSASVLDVRRSVSDRELALSFRPYRPHSGPHWPRLLKANGKFPHVKTDFDKWVDEDEEDELDRGATRATEALFLKNFFFASPAARRRGRRARVVVVVAKLFYLSSAPPLPSLFNQTPRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7H8</accession>
    <name>C1N7H8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_53699</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063901.1">
        <property type="nucleotide sequence ID" value="XM_003063855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7H8"/>
    <dbReference type="STRING" id="564608.C1N7H8"/>
    <dbReference type="GeneID" id="9689180"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53699"/>
    <dbReference type="eggNOG" id="KOG3720">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GMETHLP"/>
    <dbReference type="OrthoDB" id="10257284at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF110">
        <property type="entry name" value="2-PHOSPHOXYLOSE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="261"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="314"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="585" mass="61519" checksum="4709D64C27F9ABBE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7L1</accession>
    <name>C1N7L1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phytoene dehydrogenase</fullName>
            <ecNumber evidence="10">1.3.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PSD2</name>
        <name evidence="13" type="ORF">MICPUCDRAFT_49039</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene with a concomitant isomerization of two neighboring double bonds at the C9 and C9' positions from trans to cis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>2 a plastoquinone + 15-cis-phytoene = 9,9',15-tri-cis-zeta-carotene + 2 a plastoquinol</text>
            <dbReference type="Rhea" id="RHEA:30287"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:48717"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
            <dbReference type="EC" id="1.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carotenoid biosynthesis; lycopene biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Plastid</location>
            <location evidence="10">Chloroplast</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 10">Plastid</location>
            <location evidence="2 10">Chromoplast</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.5" evidence="10"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063922.1">
        <property type="nucleotide sequence ID" value="XM_003063876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7L1"/>
    <dbReference type="STRING" id="564608.C1N7L1"/>
    <dbReference type="GeneID" id="9689361"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49039"/>
    <dbReference type="eggNOG" id="KOG0029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WKEHAMT"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="UniPathway" id="UPA00803"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009509">
        <property type="term" value="C:chromoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016166">
        <property type="term" value="F:phytoene dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000091">
        <property type="entry name" value="15-cis-phytoene desaturase, chloroplastic/chromoplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014102">
        <property type="entry name" value="Phytoene_desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02731">
        <property type="entry name" value="phytoene_desat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF45">
        <property type="entry name" value="15-CIS-PHYTOENE DESATURASE, CHLOROPLASTIC_CHROMOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6" id="KW-0957">Chromoplast</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="12">
        <location>
            <begin position="94"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH51544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="562" mass="61720" checksum="8D00ED361D66ADAE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7P0</accession>
    <name>C1N7P0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_30088</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063939.1">
        <property type="nucleotide sequence ID" value="XM_003063893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7P0"/>
    <dbReference type="STRING" id="564608.C1N7P0"/>
    <dbReference type="GeneID" id="9689380"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30088"/>
    <dbReference type="eggNOG" id="KOG1133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QTHQFRD"/>
    <dbReference type="OrthoDB" id="267079at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034085">
        <property type="term" value="P:establishment of sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF41">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE DDX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="1"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="50"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="627"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="181"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="634"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH51561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="770" mass="81362" checksum="1AC72BAC22AB7965" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7R2</accession>
    <name>C1N7R2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53797</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063952.1">
        <property type="nucleotide sequence ID" value="XM_003063906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7R2"/>
    <dbReference type="GeneID" id="9689579"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53797"/>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317">
        <property type="entry name" value="BLR8090 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317:SF1">
        <property type="entry name" value="ZINC-RIBBON DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="35"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="103"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="183"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="235" mass="27019" checksum="779366DC295D37CC" modified="2009-05-26" version="1">MVKKGQKGPGKPFLEWCAENGERGERLANEFREELPTELTKGSKYEAKWKCLKCKHVWRAKMFSRTKSDKPCGCPKCANRMPASKTSNFLVWCEKNGELGKKLSREYVDKDKPPTAVTKGSDYKALWKCSNVECKHVWRAKMLNRTTSNKPRGCPKCANRIPLSKTNNFLTWCEKNGELGKKLSREYVDKDKPPTAVTKGSNYKALWKCEECAHEWRAKMFHRTNSDRLTGCPKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Y8</accession>
    <name>C1N7Y8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53880</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064176.1">
        <property type="nucleotide sequence ID" value="XM_003064130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Y8"/>
    <dbReference type="GeneID" id="9689617"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53880"/>
    <dbReference type="eggNOG" id="ENOG502QPKV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AMINRNN"/>
    <dbReference type="OrthoDB" id="269872at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23313:SF0">
        <property type="entry name" value="TESTIS-EXPRESSED PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23313">
        <property type="entry name" value="TSEC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="161"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="85"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="417" mass="46266" checksum="631AF3A7753DD765" modified="2009-05-26" version="1">MAEADLARYEQELLRRNAALEERAAASIARAKAVVEGTIPPSPGAADAPDLEEYSDVDDDPNDDDDDDDARARPPTPPQAKRAEVAAAAAAAKSPSKQQPPAAAKRATAASKTRARASSGDASSIIRASASASAAPDLDARDHNDAWEDAYDEDKYGRLARARIRALQDELAAQARELREAHARLKERDVELKRLLTEKLSGAFYLTPVPIRPRRRGERRFLRTFARRISPPRVPRSQSRHISTPFNSTFDAYELHPDIIARVDPRPSAAKAQKTQQTAADKERKAALDARAQLEAKERECAELRREMDRASRANKAAETEFKTRDVRLNRALEDAERYKGAEAAKGGNASTRAEADKLRGENKRLERQKAELVAAFKKQMKLIDVLKRQKIHVEAARSLQFAEEDFMRTLDAGAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8S2</accession>
    <name>C1N8S2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54220</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064324.1">
        <property type="nucleotide sequence ID" value="XM_003064278.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N8S2"/>
    <dbReference type="GeneID" id="9689765"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54220"/>
    <dbReference type="OMA" id="EFTIEAQ"/>
    <dbReference type="OrthoDB" id="2019763at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1529"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="289"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="494"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1101"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1196"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="444"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="475"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1544"/>
            <end position="1556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1597" mass="173154" checksum="40BCA7C9AEE0A218" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N918</accession>
    <name>C1N918_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54328</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064538.1">
        <property type="nucleotide sequence ID" value="XM_003064492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N918"/>
    <dbReference type="GeneID" id="9689979"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54328"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="156" mass="17377" checksum="6F44ABDD5FE5222B" modified="2009-05-26" version="1">MLIHIIICHYMLRFMYVSSRDLGSFDSALGARVGGARELVRAGVALRLKRSTFAPGSPLYFDAKAVADRRLGSFYGAIWGALAPLAQVWVLRRAPKFYEKHFEVMSFHTLLATTTATFPSSLAPAWMIEVGRLTFQARSPSHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N936</accession>
    <name>C1N936_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54350</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064549.1">
        <property type="nucleotide sequence ID" value="XM_003064503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N936"/>
    <dbReference type="GeneID" id="9689990"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54350"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964">
        <property type="entry name" value="ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964:SF113">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="32"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="284" mass="30078" checksum="304A915549E9F613" modified="2009-05-26" version="1">MQGWDAVKAALNPFAIGRRRRVPPGAGPGRVLVFAVDGSSESEDAVRFGLDNVARANDTCAFACAYKRAPRGARAMDPSGLTALEGTVDQVRTTLRRESVLSAFWTTLRFVDATALHRRAQDQRELRLAAEKIDRERCEKATTRAAEDARLVGVAGVFSDVLASEDCGNAPLRETLSRYCASRAADIVVVGSRGFGSIHRAALHIAGFGSVSEHLMRHGTWATLLVKRAGEVVDVDGKANSAKSAKSAAKEEVDTVGVGSADERKMKPTNDDGGGGGGGARDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9A6</accession>
    <name>C1N9A6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Acyl carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MICPUCDRAFT_23642</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Carrier of the growing fatty acid chain in fatty acid biosynthesis. May be involved in the synthesis of short and medium chain fatty acids. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Complex I is composed of at least 49 different subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064585.1">
        <property type="nucleotide sequence ID" value="XM_003064539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9A6"/>
    <dbReference type="STRING" id="564608.C1N9A6"/>
    <dbReference type="GeneID" id="9689861"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23642"/>
    <dbReference type="eggNOG" id="KOG1748">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TTICARE"/>
    <dbReference type="OrthoDB" id="448946at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000035">
        <property type="term" value="F:acyl binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000003">
        <property type="entry name" value="Acyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002148">
        <property type="entry name" value="PRK00982.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="ACYL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863:SF28">
        <property type="entry name" value="ACYL CARRIER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 16" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 16" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Carrier" evidence="17">
        <location>
            <begin position="10"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00057783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00063067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH51490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="88" mass="9353" checksum="2DB700FA306AF64B" modified="2009-05-26" version="1">MGAAGYLDANQVTERVVEVVKKFNKVDPSKVSPTSTFAADLGLDSLDTVEVVMAFEEEFAVEIPDAEADKISSVAEAVAYLTSNPDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Q4</accession>
    <name>C1N9Q4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46063</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH50989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064655.1">
        <property type="nucleotide sequence ID" value="XM_003064609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Q4"/>
    <dbReference type="STRING" id="564608.C1N9Q4"/>
    <dbReference type="GeneID" id="9690096"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46063"/>
    <dbReference type="eggNOG" id="KOG1203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GDSWQYL"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF45">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="3"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="211" mass="22570" checksum="4B42376B92361163" modified="2009-05-26" version="1">MDVVRQLKDAGTWVTVLQRKNDDRAEIEKMGAFLSKGDALVDKDVKKAYDMVEEYDAVVSTIGGTPADATADSVGNINLIEACVKKGEEQGRMPKFVLVTSIGTGDSQGAPPPQVYEALKPVLLEKVKAEDRLKELAKEKGLPFCIVRPGGLKSEPATGTGDTSVCGAVNRADVASLVVKCVLKDKANGKVLSAVDSEQLFDQPAFEVFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Z1</accession>
    <name>C1N9Z1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54695</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064819.1">
        <property type="nucleotide sequence ID" value="XM_003064773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Z1"/>
    <dbReference type="GeneID" id="9690260"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54695"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="77" mass="8513" checksum="3044C28981C6942C" modified="2009-05-26" version="1">MSEDDDATREIARLTLRDDAPAPAPAAAWPGGALPPWDVRLDEPSHVYTIHGDWAHRFHGVRRVLSHTGPHTTPSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA14</accession>
    <name>C1NA14_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_6234</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF2/ABP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064707.1">
        <property type="nucleotide sequence ID" value="XM_003064661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA14"/>
    <dbReference type="STRING" id="564608.C1NA14"/>
    <dbReference type="GeneID" id="9690274"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6234"/>
    <dbReference type="eggNOG" id="KOG3152">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ILAIPHC"/>
    <dbReference type="OrthoDB" id="287393at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034462">
        <property type="term" value="P:small-subunit processome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12263">
        <property type="entry name" value="RRM_ABT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039119">
        <property type="entry name" value="ABT1/Esf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034353">
        <property type="entry name" value="ABT1/ESF2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311:SF7">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="32"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="176" mass="20262" checksum="57C291617FBF70F5" modified="2009-05-26" version="1" fragment="single">ASADETTTTEKPTPVLSSKALAKSKRAQEKRGIVYLGSIPPRMKPQKLRQLLTPHGALDRIFLTPEDPAIRARRKQARSFGGNTGKNYTEGWIEFRSKKKARAAAEMLNGNPIGGKRRGSHYSDLWCMKYLPKFKWDNLTEEIEYQKALRRQKMRLELAVAKRERDFYLQKVEQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA24</accession>
    <name>C1NA24_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_43678</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064835.1">
        <property type="nucleotide sequence ID" value="XM_003064789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA24"/>
    <dbReference type="MEROPS" id="S28.A10"/>
    <dbReference type="GeneID" id="9690156"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43678"/>
    <dbReference type="eggNOG" id="KOG2182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF11">
        <property type="entry name" value="THYMUS-SPECIFIC SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910797" evidence="7">
        <location>
            <begin position="35"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="271" mass="29765" checksum="7E7F9CF9EC1B590D" modified="2009-05-26" version="1">MGPRRAPPRALPRSLALLLLLLLLLGVFPRPARALRPNALRPRLRASPRNARAHLARRVRALDAIASTEEDAPPPRPPPPARFLAQRLDHNDPAESRTWRQRYFLNDAWFLNDARPRRRRRLGEEEDGDGEQDASASDATEDAKNTSATAAARASPAIVFLCVGGEGPALRATVVTIGDAHCALAVETARRRNALVVALEHRFYGASQPTGDLSTASLRRYLSSSQALGDIAHFVTRVNEMYGLFGDDVRWIAFGGSYPGVLASWSRLKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA94</accession>
    <name>C1NA94_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_43720</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064755.1">
        <property type="nucleotide sequence ID" value="XM_003064709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA94"/>
    <dbReference type="STRING" id="564608.C1NA94"/>
    <dbReference type="GeneID" id="9690196"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43720"/>
    <dbReference type="OrthoDB" id="494131at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="255" mass="29199" checksum="C27F48B17A910BE1" modified="2009-05-26" version="1">MFAAAKRGHLHVLRWIREEVCDDDDVWDWPSICADAATGGHLRVLKFAREECKKDDDAVPWDFWTPFKAAQRGHQEVFEWVCEQSKGRFNLLPSARIAAQFGRAEILRYIVSKAPGRNYWNMLANDNYGRGYGRKSGFNVDVGRKWHKHVIALAVANGRLECAKFLLTRYAFKQKAELCKMAAAGNALPVLRWLVEEQNFPFDVRFCVGLLIRDADNWNEDTVGAIGDVEDFRAKRPEEWAVAQTLLDVANARKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAF4</accession>
    <name>C1NAF4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_9667</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064897.1">
        <property type="nucleotide sequence ID" value="XM_003064851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAF4"/>
    <dbReference type="STRING" id="564608.C1NAF4"/>
    <dbReference type="GeneID" id="9690337"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9667"/>
    <dbReference type="eggNOG" id="KOG0987">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MPSRWTR"/>
    <dbReference type="OrthoDB" id="1934841at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH50877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="52" mass="5843" checksum="FE5C4943B32594A2" modified="2009-05-26" version="1" fragment="single">PSRWTRRKFPVRPAFAMTVNKSQGQTIRGRVGVLLPEPVFSHGQMHVAASRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRC6</accession>
    <name>C1KRC6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Small ribosomal subunit protein uS3c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rps3</name>
        <name evidence="12" type="ORF">MicpuC_chl25</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="12"/>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7 10">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 10">Plastid</location>
            <location evidence="7 10">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRC6"/>
    <dbReference type="STRING" id="564608.C1KRC6"/>
    <dbReference type="OMA" id="THRSQWF"/>
    <dbReference type="OrthoDB" id="564115at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02412">
        <property type="entry name" value="KH-II_30S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000001">
        <property type="entry name" value="30S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_uS3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_uS3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_uS3_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF19">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10 12" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="11">
        <location>
            <begin position="39"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACO50758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="227" mass="25163" checksum="3F4C0A9A3B8BE2AC" modified="2009-05-26" version="1">MGQKVHPLGFRIGVTQTHRSQWFAKPKDYANLVKEDLVIRDYVAKHLSDASISRVNISRQVDRIEIEFFTARPRALVGAKGEALVKVREALSAKLPAHRSVALYVTKTVQPEVDAVCIAENIAMQLEKRAPFRRTIRQALRSAQQAGAVGIKVKIAGRLNGAEIARSEWSREGRVPLHTIRADIDYATARALTVYGILGIKVWVCKDDTERFKPQPSASAPSGSEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGQ6</accession>
    <name>C1MGQ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Prasinophyte-specific protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PSP2</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_70657</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CD36 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054819.1">
        <property type="nucleotide sequence ID" value="XM_003054773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGQ6"/>
    <dbReference type="STRING" id="564608.C1MGQ6"/>
    <dbReference type="GeneID" id="9680775"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70657"/>
    <dbReference type="eggNOG" id="ENOG502SEF3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CENEVEW"/>
    <dbReference type="OrthoDB" id="18585at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002159">
        <property type="entry name" value="CD36_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923:SF51">
        <property type="entry name" value="LYSOSOME MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01130">
        <property type="entry name" value="CD36"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="690"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="772"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="782"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="820" mass="88478" checksum="A2E80CF0D0C09845" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH04</accession>
    <name>C1MH04_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_3522</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054868.1">
        <property type="nucleotide sequence ID" value="XM_003054822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH04"/>
    <dbReference type="STRING" id="564608.C1MH04"/>
    <dbReference type="ESTHER" id="micpc-c1mh04">
        <property type="family name" value="Duf_1350"/>
    </dbReference>
    <dbReference type="GeneID" id="9680284"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3522"/>
    <dbReference type="eggNOG" id="ENOG502QSXN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DTICESE"/>
    <dbReference type="OrthoDB" id="4892at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010765">
        <property type="entry name" value="DUF1350"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34127">
        <property type="entry name" value="OS04G0405600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34127:SF1">
        <property type="entry name" value="OS04G0405600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07082">
        <property type="entry name" value="DUF1350"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="326" mass="34586" checksum="A4FDAE92085789B1" modified="2009-05-26" version="1" fragment="single">SSSSPTDAFAALEALLTAASESSGPSSARGWKELEGAWVLPPPNGRAAVGVVHFIGGAFVGASPQLTYRLLLESLSARGDLTIVATPYAIGFDHLRLADEIQFVFDRCVRSLGKEYDTLPVYGVGHSMGALMHALIGSRYKLPDRVGNVLISFNNKPATDAVPLFTPVVAPGLQARSNLSPLFNGISSSPLRAPARAIDASLRARAPPVVRELLPVLDQLEPVFLEVANGANEFVPKPDDSKDLVRKYYAVKRNLLLRFRDDTIDETGVLASTLTDGAAISESLDLSVKSLAGDHVRPCRQDVGADVPPELASPLIETGNLISGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHL4</accession>
    <name>C1MHL4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">serine O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_30855</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="3"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054975.1">
        <property type="nucleotide sequence ID" value="XM_003054929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHL4"/>
    <dbReference type="STRING" id="564608.C1MHL4"/>
    <dbReference type="GeneID" id="9680206"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30855"/>
    <dbReference type="eggNOG" id="KOG4750">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DPACTSF"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000002">
        <property type="entry name" value="Serine acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="entry name" value="serine acetyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010493">
        <property type="entry name" value="Ser_AcTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053376">
        <property type="entry name" value="Serine_acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041874">
        <property type="entry name" value="EPS_EpsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42811">
        <property type="entry name" value="SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06426">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00971">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine acetyltransferase N-terminal" evidence="7">
        <location>
            <begin position="90"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="350" mass="36976" checksum="F75B33C8C0DF9B59" modified="2009-05-26" version="1">MEPLYPKSRSPVASCRKFSTVFGTSFPKRPMTTRPAGFPPIATSKYTLFVISLLQIIGDVSGAGQSPAANAGAAAAAAAAAADPTRAARRDTMCKEARADADKEPALASYLFSTILAHKSLEDALAFVLANKLKSTVLLDSQLLELFSATYRRDGHLVKMAQADMQAYIERDPACEKYMHILLFFKGFQAIQAHRVASALWKQDRKPLALLLQSRISEIFHVDIHPGANIGAGIMLDHATGVVIGETAVVEDNVSILHGVTLGGTGTKDGDRHPKIGTGVVIGAGVTILGNLKVGANSKIGAGSVVLRDIPENCTAVGIPARLVGGPKPESQPSLSMDQVSGLSDYAYDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHP2</accession>
    <name>C1MHP2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_11510</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055526.1">
        <property type="nucleotide sequence ID" value="XM_003055480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHP2"/>
    <dbReference type="STRING" id="564608.C1MHP2"/>
    <dbReference type="GeneID" id="9680856"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11510"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01697">
        <property type="entry name" value="PARVALBUMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="34"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="72"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="142" mass="15868" checksum="FB8BA035704941E8" modified="2009-05-26" version="1" fragment="single">EDVKEAFREFDLDKNGYVGAAEISHILQSMGEKATDDEVDEMILMADLDGDGQVSFDEFFKLINSFQGMPPPPGDKVKFAFQVFDLDGSGSIDADELRKIVKATNMASEKQLTRKVEWLMKQCDSDGDGQISFDEFVNLAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHP6</accession>
    <name>C1MHP6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_61408</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055529.1">
        <property type="nucleotide sequence ID" value="XM_003055483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHP6"/>
    <dbReference type="GeneID" id="9680833"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61408"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="159" mass="17271" checksum="6BFED449C4BBA2EB" modified="2009-05-26" version="1">MSRMITFTPLNSSPRRRGRARFVLFSSRTGNPSGSWFGHLTSLYGLAALPAPRLVSLRMPFGIGLREVVASATSLSCLSCSPEPPPEPPTASSSPWTVIRVRYSRSSSSPKAIARSLRVAVARLDLSRALCFVLASLSNTRALPFARRAVVCRAGPRWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHW3</accession>
    <name>C1MHW3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_50343</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055561.1">
        <property type="nucleotide sequence ID" value="XM_003055515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHW3"/>
    <dbReference type="STRING" id="564608.C1MHW3"/>
    <dbReference type="GeneID" id="9680380"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50343"/>
    <dbReference type="eggNOG" id="KOG0381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MKNMGGK"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF32">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="36"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="36"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="87" mass="9660" checksum="811B4147C7666BE6" modified="2009-05-26" version="1">MAPKKATKAAPKAKKVISKSPKKAAKKAKVDKKDKPKRAPGPYMLFCKEMRPKIVAANPKFTFGEVGKKLGEEWKKLSDAKKASYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIX4</accession>
    <name>C1MIX4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cysteine synthase</fullName>
            <ecNumber evidence="9">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_31117</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="9"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055210.1">
        <property type="nucleotide sequence ID" value="XM_003055164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIX4"/>
    <dbReference type="STRING" id="564608.C1MIX4"/>
    <dbReference type="GeneID" id="9680635"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31117"/>
    <dbReference type="eggNOG" id="KOG1252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NAWIPQQ"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000006">
        <property type="entry name" value="Cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000130">
        <property type="entry name" value="Cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="5 7 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="10">
        <location>
            <begin position="2"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="164"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH60462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="308" mass="32326" checksum="A0F5FA4E730D48D7" modified="2009-05-26" version="1">MVYLNKVTEGCVAEIAAKLEIMEPCCSVKDRIGFSMIADAEEKGAITPGKTMLVEPTSGNTGIGLAFIAAAKGYDLTLTMPASMSLERRILLKAFGADLVLTDPAKGMKGAVMKAEELGAANKNAYILQQFENPANPKVHFETTGPEIWEDTAGQIDILVCGVGTGGTVTGTGRYLKSKNPNVKVVAVEPKESAVLSGSGPGPHKIQGIGAGFIPGILDTEILDEIIQVGSDDAIEMAKELALKEGLMVGISSGAAALAAIELAKRPENAGKLIGTVFPSFGERYLSSALYSSIREEAEGMTFDKEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJM8</accession>
    <name>C1MJM8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphohistidine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55024</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055847.1">
        <property type="nucleotide sequence ID" value="XM_003055801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJM8"/>
    <dbReference type="STRING" id="564608.C1MJM8"/>
    <dbReference type="GeneID" id="9681627"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55024"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2019724at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07040">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47623">
        <property type="entry name" value="OS09G0287300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47623:SF1">
        <property type="entry name" value="OS09G0287300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="352" mass="36999" checksum="F04B59450972D71D" modified="2009-05-26" version="1">MSSATAPRVRASAPRARLPRPTTTTTTTTRRPAAASASPLHRRSLLRRGRVAARAASASADAPPPNTPLRMIVLRHSDSCTEDASLKDHDRPLTSRGRALANGLAKALAASDDGGDGAWGAPDLVLCSASTRSRETLEELVRAHAPIGDATTHFLGSLYHFAAMDGVTAAHLKETIVKTSEAAAAEKKKNGGGGGGVKTVMCIGHNKGWEEAASEFAGEPVKLNVANAALLEYVGDGGEDWAKVFDGARGAGGLGEKSGAIRVHVRPRAVEGRSRRGARRDDAAAAAGAAGGRHVGGGRAHPGAVRVTKTRQESSRDRRVRSSGADAILLRIIRFFFTYVYVYEYLRTSTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJR3</accession>
    <name>C1MJR3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55064</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056256.1">
        <property type="nucleotide sequence ID" value="XM_003056210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJR3"/>
    <dbReference type="GeneID" id="9681427"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55064"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="163" mass="17426" checksum="731B2091AB6DB906" modified="2009-05-26" version="1">MPGFDRPAPSTATRLGPSFPWQEENALQRHWTLAARGKAPARDEGPDAPLDLDAWIRRVRGDDDGDDGRAGSASAPRGAEEEEEEEEEARVEPAARGGDEEDGDARGANDEDVAASGGAARDWNNPAPPSLEDVLASGAMKRDATVAQSLAGGYRRFYCEDAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK27</accession>
    <name>C1MK27_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_64183</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055919.1">
        <property type="nucleotide sequence ID" value="XM_003055873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK27"/>
    <dbReference type="STRING" id="564608.C1MK27"/>
    <dbReference type="GeneID" id="9681458"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64183"/>
    <dbReference type="eggNOG" id="ENOG502SCTD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QHLNGHK"/>
    <dbReference type="OrthoDB" id="162638at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.410.60:FF:000001">
        <property type="entry name" value="50S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_bL35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_bL35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_bL35-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_bL35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_bL35_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="L35p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="131" mass="13777" checksum="1DF9708CB6216D94" modified="2009-05-26" version="1">MASFVMSAGATASGTNARVSTNARVSGLGFRRAVAALPRVTSAPVAKSVAPSAVVTTCGKPGAKAKTRKSAAKRYKVTASGKVLHRRPGKQHLNGHKTTERKTRLSGERQVGRAQIPLVKGCLPYLKSKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK62</accession>
    <name>C1MK62_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_8338</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055941.1">
        <property type="nucleotide sequence ID" value="XM_003055895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK62"/>
    <dbReference type="STRING" id="564608.C1MK62"/>
    <dbReference type="GeneID" id="9681470"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8338"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552819at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF18">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="147" mass="14716" checksum="DA80FDC1F3B463FE" modified="2009-05-26" version="1" fragment="single">IIVRVEAVGLNFRDVLNVLGMYPGDPGALGSDYAGVVLGGANHFGRSVFTPGTEVFGLAPGCLGTRVVASALTAVEKPPSVGFADAAGCPTIFVTVDLALLEASPQDGVAPKSVLVHSATGGVGLAACQILAARRIKTIVTAGSTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKB0</accession>
    <name>C1MKB0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_64282</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056356.1">
        <property type="nucleotide sequence ID" value="XM_003056310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKB0"/>
    <dbReference type="STRING" id="564608.C1MKB0"/>
    <dbReference type="GeneID" id="9681480"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64282"/>
    <dbReference type="OMA" id="TACAFAT"/>
    <dbReference type="OrthoDB" id="727118at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="339"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="439"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="626" mass="68166" checksum="25E7BF572D577C51" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLH1</accession>
    <name>C1MLH1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55712</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056167.1">
        <property type="nucleotide sequence ID" value="XM_003056121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLH1"/>
    <dbReference type="GeneID" id="9682034"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55712"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="235" mass="26240" checksum="D479B1196283A216" modified="2009-05-26" version="1">MTAVEYAQQLSLLEGGSSLKRQREDTSAPSPAVVSGCGRTLNFGSATRPATPAAPRVVQTTLNQQSGPTESIIRQGTDLTTELVDDTLGDNDRLATMFDMEPVLHKYTDADADVGERIKNAPELYILRGLLERVGCLLYDKGIFPETVKSQGKRKGFRLYTRNGDFANFVRVVYIKLVEFIIPKDIKIEEEGENYKTAIRTMNSEIFADLRPCINTYITQGYIRRGIIEDGVVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLI3</accession>
    <name>C1MLI3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55725</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056570.1">
        <property type="nucleotide sequence ID" value="XM_003056524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLI3"/>
    <dbReference type="GeneID" id="9681842"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55725"/>
    <dbReference type="eggNOG" id="ENOG502QPZJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45251at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35512">
        <property type="entry name" value="OS11G0550900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35512:SF1">
        <property type="entry name" value="OS11G0550900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="208" mass="22638" checksum="90E756D7FAFACC27" modified="2009-05-26" version="1">MRLGEFVVTIGVLAVTLGTKDLPILARGLGRLTGRALGFISELRADAEILTRSANVDAMHNEMRRGVSDLVSVTEEIRTGLDPLTLGRRILTEVRGESARVFRGNVPRQSEQLREHLPARLSVSSLSDRQGMLVACPNQRTSTSLNYIPISAVSLGHRSRNLIVISGVDLLDEAVVEAEVAYRVSMSHPVGYHKGKVVSLTAASWDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLR7</accession>
    <name>C1MLR7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_56246</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056809.1">
        <property type="nucleotide sequence ID" value="XM_003056763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLR7"/>
    <dbReference type="STRING" id="564608.C1MLR7"/>
    <dbReference type="GeneID" id="9682248"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56246"/>
    <dbReference type="eggNOG" id="ENOG502S173">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NQGTLWR"/>
    <dbReference type="OrthoDB" id="497832at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002128">
        <property type="term" value="P:tRNA nucleoside ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18098">
        <property type="entry name" value="SpoU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="TRNA/RRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786:SF6">
        <property type="entry name" value="TRNA_RRNA METHYLTRANSFERASE SPOU TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="6">
        <location>
            <begin position="119"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="264"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="292" mass="31489" checksum="218A4D63C0DDDAFE" modified="2009-05-26" version="1">MEVPSTSGTPAVLRYVYPGVTPRNGRLVTAGAATLLSGCEIRDLLANDGVDVTRWQLRFQDKRNEGWARLEPDTMIAFDDPDRMRLDVALEPVPRPADARRLQGEDERDGYFGIGVVGGKNEANQGTLWRSAWTCGAAFTFTVAQRFAKSSADTVKVWTSLPAYAYEDWGAFASAQPHACSWVAVEMGTDATPLEEFEHPDRAIYVLGSEDNGLPSSVLRACAHRVALPAAEGRTASFNVAACGSVVMYDRVAKRRRAEGGVARLRQGDSLPGGRVGVDSAKPSQVLASSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLU8</accession>
    <name>C1MLU8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="6">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_25687</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="6">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="6"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057281.1">
        <property type="nucleotide sequence ID" value="XM_003057235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLU8"/>
    <dbReference type="STRING" id="564608.C1MLU8"/>
    <dbReference type="GeneID" id="9682267"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25687"/>
    <dbReference type="eggNOG" id="KOG0557">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ATIEWEA"/>
    <dbReference type="OrthoDB" id="537444at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000003">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006257">
        <property type="entry name" value="LAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01349">
        <property type="entry name" value="PDHac_trf_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="70"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="8">
        <location>
            <begin position="208"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="498" mass="50925" checksum="3BDA1203421E39B6" modified="2009-05-26" version="1">MAFRHATRRLAAAVARTDTTAARAICAHPFAGGGSCALARDNASFRAAVASARAPRWSRSFAAGADYPPYQEITMPALSPTMTQGNIAEWKVKEGDKVSAGDVLADIETDKATMALESMEDGYVAKILHGTGASDVEVGTLVAIMVEDEGDVGKFGGFTVSAAAAPAARTATPAAAPAAAAPAAAAAPAASAASAPVSAPRHAGARVFATPKARVMAAEAGIAIDQIDGSGPGGRILMSDVSHAIANGVAPRAAAGSADGAADGFARFFPPYEDVSVTTIKKVTAARLTESKRTVPHFYLSVDVRMDQIVSARAKLNAGKEKGKISVNDFVVKAAASALKQVPDVNASWMGDKIRVYKNADISVAVQTDAGLMVPIVRNACGLGLSGISSEVRALAGKAKEGKLSPADMIGGTFTISNLGMFGIKQFAAIVNPPQAAILAVGAARKEVVKKADGSGYEEALLMSATLSCDHRVVDGAVGAQWLGAFKAFMEDPVTMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMD3</accession>
    <name>C1MMD3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_46781</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Putative transcription factor.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057382.1">
        <property type="nucleotide sequence ID" value="XM_003057336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMD3"/>
    <dbReference type="STRING" id="564608.C1MMD3"/>
    <dbReference type="GeneID" id="9682351"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46781"/>
    <dbReference type="eggNOG" id="ENOG502SGI5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IIHALEC"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044607">
        <property type="entry name" value="RKD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003035">
        <property type="entry name" value="RWP-RK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373">
        <property type="entry name" value="PROTEIN RKD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373:SF2">
        <property type="entry name" value="RWP-RK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02042">
        <property type="entry name" value="RWP-RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51519">
        <property type="entry name" value="RWP_RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RWP-RK" evidence="8">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="138"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="409" mass="41245" checksum="289BD658935170CE" modified="2009-05-26" version="1">MPKKRGGGQSKSLTVEELSANFHLPINDVARKLGLCVTVLKQRCREHGITRWPYRKVKKLDTIIHALEVAAPGRAAAAAPIAADSAEASEKLALSVGDAERERLESVRKTREVLITDPNSKAHLRIGKLKAVRRRVARVSAGAGGDSSDRDTTTDDGYARRRLSTGSGNSGGVDGLLEAAASLSDGETTPGTPRRGAKGEHTPRERSPRTSGRSTFGDDDIAEELGNAAAALGALTEAALGRASGGGGEAQTASKPAAAALIAKPAPAPALGGFDPTAFAAQLAAFTPPPAAAAAAQAARGAAPVPTMPNMMAACMNPSLMFAWMSGVANAAAAAQPAGVGVGVGPGQAAGAAAWNPNAFAQMLAQANAFTARAQAQAQAAVQAAAGQQSAVAPPAAPPANIESAHQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMU4</accession>
    <name>C1MMU4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_56659</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056990.1">
        <property type="nucleotide sequence ID" value="XM_003056944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMU4"/>
    <dbReference type="GeneID" id="9682904"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56659"/>
    <dbReference type="OMA" id="DAHERAC"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="18257" checksum="D5E9F66C8C6A754D" modified="2009-05-26" version="1">MKSSPNAPPLPSLLLRAAPARSWLDAHERACASAGTDPDAAPFVPTTAQAEVAKHLAHRLDLARVVSRDLDAQIASTADALARIERVTAAAESVRETDERRARFAREGGADRRAALPMGADADAAPSPHAADGRTLARELLAASEDPQKTEAYAAALRLRKRLVTDELLALGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN43</accession>
    <name>C1MN43_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prokaryotic-like GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FTSZ</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_70241</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057513.1">
        <property type="nucleotide sequence ID" value="XM_003057467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN43"/>
    <dbReference type="STRING" id="564608.C1MN43"/>
    <dbReference type="GeneID" id="9682952"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70241"/>
    <dbReference type="eggNOG" id="KOG0229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NHKEYAL"/>
    <dbReference type="OrthoDB" id="270720at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="449"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="715"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="715"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="878" mass="90156" checksum="961B5D078830A5E3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNL2</accession>
    <name>C1MNL2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_55945</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057126.1">
        <property type="nucleotide sequence ID" value="XM_003057080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNL2"/>
    <dbReference type="STRING" id="564608.C1MNL2"/>
    <dbReference type="GeneID" id="9682139"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55945"/>
    <dbReference type="eggNOG" id="ENOG502RXWT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CARDIYD"/>
    <dbReference type="OrthoDB" id="2744543at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045039">
        <property type="entry name" value="NSI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43626">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43626:SF4">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="100"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="242"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="298" mass="30581" checksum="CF3AF824F6D8EFF2" modified="2009-05-26" version="1">MVVAARAAATATRAPCLARPRALSSRPWTRAPAPPRATPRDRAVAVVAGSFASSADARRARRREPPGLAFTTRASDVDARELASLLGGGGGDDDDDALAAKLRAMLDASEAVVVAAFASSSSSSSSSSSSSSSSPSPMERMRYLNPFASRFGGDVRGKALVGFAHAATDGAMVATVDVVVVREDARGAGVGEKLVRRLGEELCARDIYDVGVRAPRERRAFFARCGFGPDAEGATLMALPPGGGGGGGGGATGAKGGDRARELAKTFTPERTLKNDGAGLREMMLKEMRDADGTARAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNU0</accession>
    <name>C1MNU0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_38598</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057170.1">
        <property type="nucleotide sequence ID" value="XM_003057124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNU0"/>
    <dbReference type="GeneID" id="9682609"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38598"/>
    <dbReference type="OrthoDB" id="414028at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910368" evidence="2">
        <location>
            <begin position="26"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="280" mass="29939" checksum="FA6559979F32FE0B" modified="2009-05-26" version="1">MARAKPPKPLDALAVFTLLLSHCLALQVAKDAQRLVEWRSLFSALPTILLATAIIRANRSPSSTGRLADLSHAGVLVLLVNGSQSNHVLLELATCVAVAIATWGKATSSGGADANALAVSSSRRAAVEDRLVRSCRAILFALYLSTGVAKLNDAWHDPKTSCCVGMFVAAASTLGVSASFSSPAVLRAMPYAATVFELSFPTLLWVASRYRDDAYVVPWLKVSYTPVVTRRKRAKIIMRCLCVAGAAFHVVIALPPPPMSAYPFRRVLLYTGSRTTASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNW6</accession>
    <name>C1MNW6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Glycosyltransferase family 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_38613</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056716.1">
        <property type="nucleotide sequence ID" value="XM_003056670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNW6"/>
    <dbReference type="GeneID" id="9682622"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38613"/>
    <dbReference type="eggNOG" id="KOG3917">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="508846at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046525">
        <property type="term" value="F:xylosylprotein 4-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030166">
        <property type="term" value="P:proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003859">
        <property type="entry name" value="Galactosyl_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027995">
        <property type="entry name" value="Galactosyl_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19300">
        <property type="entry name" value="BETA-1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19300:SF30">
        <property type="entry name" value="BETA-1,4-GALACTOSYLTRANSFERASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13733">
        <property type="entry name" value="Glyco_transf_7N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02050">
        <property type="entry name" value="B14GALTRFASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910371" evidence="12">
        <location>
            <begin position="27"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Galactosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="101"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Galactosyltransferase C-terminal" evidence="13">
        <location>
            <begin position="203"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="31"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH58361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="314" mass="33817" checksum="A3884883636A8255" modified="2009-05-26" version="1">MPSAAKAARALGVLLLASALASLCLGGVRDLRPAPRRVPEKTTSTRSPSAPSAPSARTPRASSFDDPSRAVAPPRSSSASSSSRDAVASASSASSATSPLLCVVAPYRDRPGKEGEVERFVAHASRWLPRVAGVARHSTWIVHQDDDLRFNRGWLLNVGVALARTTDACDYFAVHDIDLLPTSARLPYDAVPETATHLSPPGVHPEYIYPSFKGGAWLFTWEQLKAFDGYSHAYWGWGQEDDDLGARMRRANVAHGAALKYPGPREEPSDAAAAAAANETCTGRVAKCDHDPTERECGIYPYAALLTMRRRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPC4</accession>
    <name>C1MPC4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional lysine-specific demethylase and histidyl-hydroxylase</fullName>
            <ecNumber evidence="3">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_56226</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ROX family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="3"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056797.1">
        <property type="nucleotide sequence ID" value="XM_003056751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPC4"/>
    <dbReference type="STRING" id="564608.C1MPC4"/>
    <dbReference type="GeneID" id="9682236"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56226"/>
    <dbReference type="eggNOG" id="ENOG502S0FU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RWSDPWL"/>
    <dbReference type="OrthoDB" id="425950at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.30">
        <property type="entry name" value="50S ribosomal protein L16 arginine hydroxylase, Chain A, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="NO66-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="MINA53 MYC INDUCED NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096:SF8">
        <property type="entry name" value="RIBOSOMAL OXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="JmjC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="5">
        <location>
            <begin position="149"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="433" mass="47691" checksum="1CE52D8B46E8C1E5" modified="2009-05-26" version="1">MSAVRAIPTACHAKPRTPNPRAPARHTRAPVSRACASSSLREGVVAIDELHAQLPFDRDTWKMFMSEYWQKRPCVIRGAVNSTIPEIDADELSGLACENVFQPRIIRKGEGRSDWALEMGPFSEDELRALPTAGSWCLIMNDLEKHIREVKGLLALFDHFPRWRVADVQASLSADGGSVGPHSDQFDVFLIQAEGNKAWSISDSAEYAPDNESAFYQDIDVRVLKDFRPTSSSLLERGDMLYLPPKVAHHGVAKGCDTVCVTYSVGFLAPTHDELVSSFAQASVNERAAVERWSDPWLEPQCDVGKISSAAVTHATEIIRNAMPKNETDVARWFGCHVTGSGGVDDAFFAPVDDVTADELIAEWTETGFLFRRGDIKFAIIEDVSDGSLDGCLFFAAGSVWTVKSPRCIEFARHVANHDEIEADEQGAIARLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPM4</accession>
    <name>C1MPM4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_56959</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057606.1">
        <property type="nucleotide sequence ID" value="XM_003057560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPM4"/>
    <dbReference type="STRING" id="564608.C1MPM4"/>
    <dbReference type="GeneID" id="9683418"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56959"/>
    <dbReference type="eggNOG" id="KOG1111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PMWDFIR"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03814">
        <property type="entry name" value="GT4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050194">
        <property type="entry name" value="Glycosyltransferase_grp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947:SF3">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13692">
        <property type="entry name" value="Glyco_trans_1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="562"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="598"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="697"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="731"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="4">
        <location>
            <begin position="117"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="3">
        <location>
            <begin position="580"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="769" mass="81394" checksum="907F93EDB06A8806" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPM6</accession>
    <name>C1MPM6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56961</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057607.1">
        <property type="nucleotide sequence ID" value="XM_003057561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPM6"/>
    <dbReference type="STRING" id="564608.C1MPM6"/>
    <dbReference type="GeneID" id="9683419"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56961"/>
    <dbReference type="OMA" id="YLHAKPL"/>
    <dbReference type="OrthoDB" id="497887at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110102">
        <property type="term" value="P:ribulose bisphosphate carboxylase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.210">
        <property type="entry name" value="Chaperonin-like RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038052">
        <property type="entry name" value="Chaperonin_RbcX_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003435">
        <property type="entry name" value="Chaperonin_RcbX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791">
        <property type="entry name" value="CHAPERONIN-LIKE RBCX PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791:SF1">
        <property type="entry name" value="RUBISCO CHAPERONE RBCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02341">
        <property type="entry name" value="RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158615">
        <property type="entry name" value="RbcX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="145" mass="16455" checksum="8661398727B41A89" modified="2009-05-26" version="1">MNSDDVDEPETFVVPPDAFVDATTGESMTPERKAGVALGNLFTMAATRVILDQFTGTRHRSPVYYKMVDFLNENPLRNGNEWLAKLMREPDNDLRITAMRIIETRRVFADTEFNWDVVESVTKEEIAGDTLEMTKSFLTESLTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPN6</accession>
    <name>C1MPN6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56974</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057614.1">
        <property type="nucleotide sequence ID" value="XM_003057568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPN6"/>
    <dbReference type="GeneID" id="9683025"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56974"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="14"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="186" mass="20014" checksum="ECB3407210D3FAE0" modified="2009-05-26" version="1">MPFVDDSLVDQHEARAEAARACFLQHDVDGSGSIDASELAAALESLGLREPGESDESFRALVGRCMHEHDINGGGTLSFNEFSHLYNAVRGVAVENARGTGGFAVVRKATHARTKTQYAIKIINLDVDGDAGHASPNANATTTRGGDVDDEEEHERASIEDIADEIKVRSIHWSPYDRVGDVDADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPP4</accession>
    <name>C1MPP4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">methionine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Methionyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_70268</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="1"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057617.1">
        <property type="nucleotide sequence ID" value="XM_003057571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPP4"/>
    <dbReference type="STRING" id="564608.C1MPP4"/>
    <dbReference type="GeneID" id="9683427"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70268"/>
    <dbReference type="eggNOG" id="KOG0436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2241">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VIWPCIL"/>
    <dbReference type="OrthoDB" id="24670at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.220.10:FF:000002">
        <property type="entry name" value="Methionine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326:SF2">
        <property type="entry name" value="METHIONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="METHIONYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 12" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="15">
        <location>
            <begin position="549"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="513"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH57568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="632" mass="70002" checksum="47E289BE0BD8DC4D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPW0</accession>
    <name>C1MPW0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bardet-biedl syndrome 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_16331</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058018.1">
        <property type="nucleotide sequence ID" value="XM_003057972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPW0"/>
    <dbReference type="STRING" id="564608.C1MPW0"/>
    <dbReference type="GeneID" id="9683114"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16331"/>
    <dbReference type="eggNOG" id="ENOG502QPS5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KGEGCFK"/>
    <dbReference type="OrthoDB" id="414590at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034464">
        <property type="term" value="C:BBSome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056334">
        <property type="entry name" value="BBS7_GAE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056335">
        <property type="entry name" value="BBS7_hairpin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056333">
        <property type="entry name" value="BBS7_pf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056332">
        <property type="entry name" value="Beta-prop_BBS7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16074">
        <property type="entry name" value="BARDET-BIEDL SYNDROME 7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16074:SF4">
        <property type="entry name" value="BARDET-BIEDL SYNDROME 7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23360">
        <property type="entry name" value="BBS7_GAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23349">
        <property type="entry name" value="BBS7_hp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23361">
        <property type="entry name" value="BBS7_pf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23743">
        <property type="entry name" value="Beta-prop_BBS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BBS7 beta-propeller" evidence="5">
        <location>
            <begin position="21"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="BBS7 GAE" evidence="3">
        <location>
            <begin position="394"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="BBS7 platform" evidence="4">
        <location>
            <begin position="507"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="BBS7 helical hairpin" evidence="2">
        <location>
            <begin position="613"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="344"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="734" mass="79596" checksum="CA20835682A64DE2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ54</accession>
    <name>C1MQ54_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_32900</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057698.1">
        <property type="nucleotide sequence ID" value="XM_003057652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ54"/>
    <dbReference type="GeneID" id="9683506"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32900"/>
    <dbReference type="eggNOG" id="KOG1385">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WTCRIKE"/>
    <dbReference type="OrthoDB" id="6372431at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017110">
        <property type="term" value="F:nucleoside diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009134">
        <property type="term" value="P:nucleoside diphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF83">
        <property type="entry name" value="GUANOSINE-DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01238">
        <property type="entry name" value="GDA1_CD39_NTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="234"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="477" mass="50912" checksum="A9A598CB256445BB" modified="2009-05-26" version="1">MRRRYSGARDSPAELLWKFRGVVAVVSVPIFLFLAVLLLMPRAADDSLDFSSNAMDRDARLSQAASSPTANNAAADDDARKYAIVFDAGSTGSRVHVYRFDETEDGSLALVDDTFEQLKPGLSSFAKFPSEGADSIDPLLEIAMKTVPEARRATTTVEVRATAGLRLLPGKEADGLLDAVRAKLKGYPFSFNDDSVSIMDGAEEGAFQWLTMNYLLGNLDGDLSDTVATVDLGGGSVQLAYAAEEKHVKAAPEGYFKAMTSGSKKYHVYVYSHLGFGIMAARAAVLGSANGAPSPCVPTGHSGTYEYGGKTHNVTGGSTPANATECKRVVNGVLAPDTKCGKVVRQTDCSFNGAWDGSRGPGTGKFYLSSYLFDRVTQAGLVDPGEPSGTTTPGEILKVAEKACEMTVDQIAVEYRDVDAKDAPYYCHDLSYAHSLLTVGYKIHDEDVVTLVKQVEYNGQLTEAAWPLGAAINALSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQE4</accession>
    <name>C1MQE4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57261</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057741.1">
        <property type="nucleotide sequence ID" value="XM_003057695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQE4"/>
    <dbReference type="GeneID" id="9683179"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57261"/>
    <dbReference type="OMA" id="ECEFTHA"/>
    <dbReference type="OrthoDB" id="10690573at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36721:SF1">
        <property type="entry name" value="OS04G0446401 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36721">
        <property type="entry name" value="PROLINE-RICH FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="857"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1070"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="443"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="652"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="758"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="773"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="857"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1161" mass="124143" checksum="A28189845DE396EA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQI7</accession>
    <name>C1MQI7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57306</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057766.1">
        <property type="nucleotide sequence ID" value="XM_003057720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQI7"/>
    <dbReference type="GeneID" id="9683571"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57306"/>
    <dbReference type="OMA" id="SWYDKDY"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="398" mass="43038" checksum="83D75320DFC99549" modified="2009-05-26" version="1">MPAASSRERNFQNDEDEERTLLLVVTRRRRGRPRAHARSRAARRSIARPARRRWDTVDVFERRRANVVVVVVVVVCATAATMGRSRGESPSSSDGESSSSEDRRASERRKEKKHKKEKKHKSKKEKKSKKRKRGDDEEERREKEMLKEAKRYLRMQRELGMSAAGGAGAGGVGVAAAAVAVENARVAAAAAAADDDVPPTAARAAAKRVADARKAALEEDAALASVGALRESLLDFRAAGLPPSLTDVGAGGDAAGAANARVDAATAKARRRLEKERLEELAGPKATGRDALREKRLGIRAEHRAYQAQRDDAMLGGMRELGGSELGGGGGDEFRAALAAKRRAQERRANARGTTADPRVLAARAEAHERAERERMSAFHELVGDAGGEKMTIPRRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQQ7</accession>
    <name>C1MQQ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_8098</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057801.1">
        <property type="nucleotide sequence ID" value="XM_003057755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQQ7"/>
    <dbReference type="STRING" id="564608.C1MQQ7"/>
    <dbReference type="GeneID" id="9683606"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8098"/>
    <dbReference type="eggNOG" id="KOG0070">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RGIWKAY"/>
    <dbReference type="OrthoDB" id="414781at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00878">
        <property type="entry name" value="Arf_Arl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051995">
        <property type="entry name" value="Ciliary_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46090">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46090:SF2">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="6"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="108"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="132" mass="14305" checksum="5691C355AFA2B36C" modified="2009-05-26" version="1" fragment="single">KLVLVGLDGAGKSTLLQTMLGEKPEKTMPTFGFNNARTKQRGFDIDLFDLGGGKRIRGIWKAYMADVHGCVFVVDAADADRLDECREVFADTLRDPHLSGKPIVVFANKQDLPSAKSEAQIATALGLATLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQW6</accession>
    <name>C1MQW6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bile Acid:Na+ symporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_47101</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057826.1">
        <property type="nucleotide sequence ID" value="XM_003057780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQW6"/>
    <dbReference type="GeneID" id="9683640"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47101"/>
    <dbReference type="eggNOG" id="KOG4821">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="188035at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016833">
        <property type="entry name" value="Put_Na-Bile_cotransptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640:SF5">
        <property type="entry name" value="SODIUM_BILE ACID COTRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 10 MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13593">
        <property type="entry name" value="SBF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="510"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="644" mass="68296" checksum="DA3C580F6D97E0C6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR55</accession>
    <name>C1MR55_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_7683</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058245.1">
        <property type="nucleotide sequence ID" value="XM_003058199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR55"/>
    <dbReference type="STRING" id="564608.C1MR55"/>
    <dbReference type="GeneID" id="9683683"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7683"/>
    <dbReference type="eggNOG" id="KOG0707">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="REKLAMN"/>
    <dbReference type="OrthoDB" id="6334211at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:GMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.10:FF:000002">
        <property type="entry name" value="Guanylate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.10">
        <property type="entry name" value="Guanylate Kinase phosphate binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117:SF13">
        <property type="entry name" value="GUANYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117">
        <property type="entry name" value="GUANYLATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="171" mass="18902" checksum="2CD2C4B56458EAB8" modified="2009-05-26" version="1" fragment="single">VVRRLRALRPELHFVVTATSRAPRPGEEDGVDYFFVSTEEFEKMIADGELIEHAVVYGQYKGIPKKQVREKLAMNTDVILRLDVQGAATVREMIPGATSVFVCAESEAALARRLARRGTETPDELAERVKTAREETARGVGEFDYVLVNAEGKLDDTAAKLAGIIDAVKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRI5</accession>
    <name>C1MRI5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_39554</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058314.1">
        <property type="nucleotide sequence ID" value="XM_003058268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRI5"/>
    <dbReference type="STRING" id="564608.C1MRI5"/>
    <dbReference type="GeneID" id="9683371"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39554"/>
    <dbReference type="eggNOG" id="KOG0920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CYVAFHE"/>
    <dbReference type="OrthoDB" id="5600252at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF145">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="270"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="595"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="85"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="408"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="520"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1047"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1114"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="408"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1135"/>
            <end position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1152" mass="121779" checksum="F5BBFD512B29F117" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRU5</accession>
    <name>C1MRU5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_39881</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058934.1">
        <property type="nucleotide sequence ID" value="XM_003058888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRU5"/>
    <dbReference type="GeneID" id="9684010"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39881"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="364" mass="38646" checksum="78163C8F736DB604" modified="2009-05-26" version="1">MSPREKLARRIAHVVVAIVACYTMYVLGRMPVSEPDDVLARRSWRSRISRSPRGASALAPSSLELKRAECERQGMDTCPVCGECVRRSEWGEGERARCPHCGATARERVAAIVQRERLFEPGVLEARAGGGAAAGDERFVVAYFEPNEALATRMRDAGASVIALELEGEGGRGGRRLGGGDDDDDDDGSRGGARPSRKESADAADAAAAADAAADADDDDAGPLIADLTGRGDCFPANKMRPNECLPMYSGVADGVVILDELQRLRDATFAVVQLGRVVRDGGWMQTSAPCRAGGGGGGGGTTRYACDDFRAEMEATGHFVCVDGRSALGGVDDAALKWYGLFPSRDGTAARVDQHFVCERVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRU6</accession>
    <name>C1MRU6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58237</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058571.1">
        <property type="nucleotide sequence ID" value="XM_003058525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRU6"/>
    <dbReference type="STRING" id="564608.C1MRU6"/>
    <dbReference type="GeneID" id="9684374"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58237"/>
    <dbReference type="eggNOG" id="KOG2777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4308">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RACEANE"/>
    <dbReference type="OrthoDB" id="341587at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003726">
        <property type="term" value="F:double-stranded RNA adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008251">
        <property type="term" value="F:tRNA-specific adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006382">
        <property type="term" value="P:adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002466">
        <property type="entry name" value="A_deamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10910:SF62">
        <property type="entry name" value="AT07585P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10910">
        <property type="entry name" value="EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02137">
        <property type="entry name" value="A_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00552">
        <property type="entry name" value="ADEAMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50141">
        <property type="entry name" value="A_DEAMIN_EDITASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A to I editase" evidence="3">
        <location>
            <begin position="394"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="652"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="772"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="665"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="793" mass="81384" checksum="FA6AD1FC4A7AA2E6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS48</accession>
    <name>C1MS48_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58346</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058623.1">
        <property type="nucleotide sequence ID" value="XM_003058577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS48"/>
    <dbReference type="GeneID" id="9684424"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58346"/>
    <dbReference type="OMA" id="FECARIN"/>
    <dbReference type="OrthoDB" id="10661558at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="721"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="809"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="934"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="560"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="649"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="737"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="779"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="833"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="856"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="998" mass="106496" checksum="AA6CEC860B329B51" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSE1</accession>
    <name>C1MSE1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58451</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059037.1">
        <property type="nucleotide sequence ID" value="XM_003058991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSE1"/>
    <dbReference type="GeneID" id="9684103"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58451"/>
    <dbReference type="eggNOG" id="KOG1840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4825">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VQGNDYN"/>
    <dbReference type="OrthoDB" id="66599at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052607">
        <property type="entry name" value="CEP104-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048739">
        <property type="entry name" value="CEP104_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 104 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371">
        <property type="entry name" value="GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21040">
        <property type="entry name" value="CEP104-like_TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21038">
        <property type="entry name" value="CEP104_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="TOG" evidence="3">
        <location>
            <begin position="498"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="798"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="304"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="735"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="461"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="735"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="760"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="897" mass="96034" checksum="3038C74937D7631A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSG7</accession>
    <name>C1MSG7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_40017</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059050.1">
        <property type="nucleotide sequence ID" value="XM_003059004.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MSG7"/>
    <dbReference type="GeneID" id="9684116"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40017"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HMHASEL"/>
    <dbReference type="OrthoDB" id="432528at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="187"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="794"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="243"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1264"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1404"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="794"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1534" mass="164908" checksum="939F90679FE6A4FA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSS5</accession>
    <name>C1MSS5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_57805</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058376.1">
        <property type="nucleotide sequence ID" value="XM_003058330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSS5"/>
    <dbReference type="GeneID" id="9683847"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57805"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="87" mass="8886" checksum="D2C0E989E28BC300" modified="2009-05-26" version="1">MAELQSAWGAACVDAAGEATVYGDDASTEAGGPCLTAIVFLTRATECFGRAAELVGDAKGKASSEYAAATRRARASRRALADAMKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT10</accession>
    <name>C1MT10_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_57898</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058776.1">
        <property type="nucleotide sequence ID" value="XM_003058730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT10"/>
    <dbReference type="GeneID" id="9684215"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57898"/>
    <dbReference type="eggNOG" id="KOG1386">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YVWATAG"/>
    <dbReference type="OrthoDB" id="6372431at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017110">
        <property type="term" value="F:nucleoside diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009134">
        <property type="term" value="P:nucleoside diphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24003">
        <property type="entry name" value="ASKHA_NBD_GDA1_CD39_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF83">
        <property type="entry name" value="GUANOSINE-DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01238">
        <property type="entry name" value="GDA1_CD39_NTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="280"/>
            <end position="284"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="640" mass="64292" checksum="5BA0EE28E8013B46" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT35</accession>
    <name>C1MT35_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_6662</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058791.1">
        <property type="nucleotide sequence ID" value="XM_003058745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT35"/>
    <dbReference type="GeneID" id="9683774"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6662"/>
    <dbReference type="eggNOG" id="ENOG502QTYT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CLAYICS"/>
    <dbReference type="OrthoDB" id="416096at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038938">
        <property type="entry name" value="D27-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025114">
        <property type="entry name" value="D27-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33591">
        <property type="entry name" value="BETA-CAROTENE ISOMERASE D27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33591:SF4">
        <property type="entry name" value="OS08G0114100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13225">
        <property type="entry name" value="D27-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-carotene isomerase D27-like C-terminal" evidence="1">
        <location>
            <begin position="105"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="193" mass="21463" checksum="C8EC169178EE62F8" modified="2009-05-26" version="1" fragment="single">TRYEDGALDELAIALFNRKLESALRDDAIDVKETTLPKRGFDRLVALADLISVGRSPSRQRAVVLTTLLGLIPPWVRARFKEIIRPEWRWVDEMNAVITVNAFAWLVGPCEIIPRESDGVMSAVKLRKCRYLEQCGCTASCVNFCKMPTQAFFREAFGVDAHLAPDHSDGSCVMTFGAKPPSPDPAFEAPCYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT67</accession>
    <name>C1MT67_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Starch synthase, chloroplastic/amyloplastic</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SSIA</name>
        <name evidence="15" type="ORF">MICPUCDRAFT_47271</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Chloroplast</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Amyloplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058812.1">
        <property type="nucleotide sequence ID" value="XM_003058766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT67"/>
    <dbReference type="STRING" id="564608.C1MT67"/>
    <dbReference type="GeneID" id="9683873"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47271"/>
    <dbReference type="eggNOG" id="ENOG502QTWM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TWCPWYM"/>
    <dbReference type="OrthoDB" id="512920at2759"/>
    <dbReference type="UniPathway" id="UPA00152"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009501">
        <property type="term" value="C:amyloplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010021">
        <property type="term" value="P:amylopectin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000048">
        <property type="entry name" value="Starch synthase, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45825:SF11">
        <property type="entry name" value="ALPHA AMYLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45825">
        <property type="entry name" value="GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0035">Amyloplast</keyword>
    <keyword evidence="4 11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0750">Starch biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Starch synthase catalytic" evidence="14">
        <location>
            <begin position="175"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="13">
        <location>
            <begin position="488"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH57267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="702" mass="77542" checksum="2D21534F78AC9F6C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT91</accession>
    <name>C1MT91_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_47278</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058823.1">
        <property type="nucleotide sequence ID" value="XM_003058777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT91"/>
    <dbReference type="STRING" id="564608.C1MT91"/>
    <dbReference type="GeneID" id="9683886"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47278"/>
    <dbReference type="eggNOG" id="KOG4401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QAQVVCF"/>
    <dbReference type="OrthoDB" id="1057137at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047574">
        <property type="entry name" value="AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039683">
        <property type="entry name" value="Lsm12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019181">
        <property type="entry name" value="LSM12_ABD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13542">
        <property type="entry name" value="LSM12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09793">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00995">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52001">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AD" evidence="1">
        <location>
            <begin position="76"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS52001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="18538" checksum="3628DD9CB27C00F2" modified="2009-05-26" version="1">MGVADWGIGHVVSGVTATGEKFAGEVFTFDEGTGLAVLRAKGDIVNTHDVRILRAEGVSDLKSTPPSDPPKMEKLPVVDEARCQKREEAAVKAATISAANIGVDVTAEAQDIFDALARTLPCRWEGRSIVVLDEVKISPPYAECVGVATGDPRAVERVQKVLAMEKSKLVKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTB6</accession>
    <name>C1MTB6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_9106</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058837.1">
        <property type="nucleotide sequence ID" value="XM_003058791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTB6"/>
    <dbReference type="GeneID" id="9684276"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9106"/>
    <dbReference type="eggNOG" id="ENOG502S188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RATAVNW"/>
    <dbReference type="OrthoDB" id="4311at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.90">
        <property type="entry name" value="Protein of unknown function DUF1823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014952">
        <property type="entry name" value="DUF1823"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08853">
        <property type="entry name" value="DUF1823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="140" mass="16171" checksum="54210D6F5AE8816B" modified="2009-05-26" version="1" fragment="single">PISNETLLKIVLSQVPDREVNELVWEALGYVKSIELDMETLEGEEVWSPDNVFPKWKAAYPEPPDVIGVRRKYWQEIDAPVKAACAALTRSVAEEHKAGIKTTLRHYGWKGFRMDGLTPNMTRRAQVANWLLYYRRELRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTE1</accession>
    <name>C1MTE1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_58037</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058848.1">
        <property type="nucleotide sequence ID" value="XM_003058802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTE1"/>
    <dbReference type="STRING" id="564608.C1MTE1"/>
    <dbReference type="GeneID" id="9683912"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58037"/>
    <dbReference type="eggNOG" id="ENOG502QQIX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IHCTKER"/>
    <dbReference type="OrthoDB" id="16573at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057228">
        <property type="entry name" value="DUF7906"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31515:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31515">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25483">
        <property type="entry name" value="DUF7906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910475" evidence="3">
        <location>
            <begin position="30"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1112"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7906" evidence="4">
        <location>
            <begin position="469"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1143" mass="121011" checksum="0F6C806F4C1615E2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTL8</accession>
    <name>C1MTL8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_26898</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058882.1">
        <property type="nucleotide sequence ID" value="XM_003058836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTL8"/>
    <dbReference type="STRING" id="564608.C1MTL8"/>
    <dbReference type="GeneID" id="9683955"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26898"/>
    <dbReference type="eggNOG" id="KOG1569">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MYIASSM"/>
    <dbReference type="OrthoDB" id="1747252at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.790:FF:000001">
        <property type="entry name" value="50S ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_uL1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_uL1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_uL1_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="329" mass="34457" checksum="F9D2C6739CFF6AAE" modified="2009-05-26" version="1">MASLTCVNAMVASKARFVGGARVSAKSSITRVGGLKAKASVSMRVTGGRQGLSVRAAGLDFAELETAASQDEDDDADWVAPVRATRKDGKSAKEARMSKRFLKALKSVPGRLNPVSPEEGIKLMMDNATAKFVESAEAHVRLNIDPKYNDQQLRATVALPKGTGKTVRVAVLCQGDNIAAAKAAGADFAGADDLVEDIAGGMLDFDLLIASPDMMPKAAKLGRALGPKGLMPNPKAGTVTPDVVTAVNEFKGGKVEFRADKQGIVHVPFGKLNFTAADLQENLVAIVAAINANRPPGAKGIYWKSLYIASTMGPSVMIDHTAVEAQVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTV0</accession>
    <name>C1MTV0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_17963</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059383.1">
        <property type="nucleotide sequence ID" value="XM_003059337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTV0"/>
    <dbReference type="GeneID" id="9684553"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17963"/>
    <dbReference type="eggNOG" id="KOG1611">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IINHANP"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="150" mass="16169" checksum="BBACC5A05A5CCE89" modified="2009-05-26" version="1" fragment="single">LEDMTSDEMMHVFKINTIGPLLVTQRLLKAGVLGTAGVGERPRGALVGNVTSKVGSVDDNGSGSGYAYRASKAALNIVNKSMSIDLADRGVLCELLHPGWVRTRMTQARSIGRGLIDAEESARGLIAAMEGKYGEVNGRWYDYKGDEIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUC8</accession>
    <name>C1MUC8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58756</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059475.1">
        <property type="nucleotide sequence ID" value="XM_003059429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUC8"/>
    <dbReference type="GeneID" id="9684612"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58756"/>
    <dbReference type="eggNOG" id="ENOG502SDWC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ELLYCCM"/>
    <dbReference type="OrthoDB" id="496594at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="268" mass="29003" checksum="E52CFD13DA5C4DE8" modified="2009-05-26" version="1">MASARVAIAPAMASASARGRLRAARAAAASSRVVASISSSLGSKRASRGAARALRERRRATTSTATRRRRDARAFALFGPPPDPALLLAEGKALYAEGERMRGYKTFERALRQDTIDVETRRELLYCCMCCNAAFGDVETAKQFLRDMNIAGLPFDVAMLDDRLMPLESSAQMRNQLVKFASGEMKSQGTVQREIFERDRAPRGNLGAMGGGGAGKPQRMGDMDLMNLEISGDTSAETKDIVKRVLGLVVASVVGFVGLFQFGLTFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUE3</accession>
    <name>C1MUE3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_47514</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059179.1">
        <property type="nucleotide sequence ID" value="XM_003059133.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MUE3"/>
    <dbReference type="GeneID" id="9684923"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47514"/>
    <dbReference type="eggNOG" id="KOG4231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CWENRRT"/>
    <dbReference type="OrthoDB" id="498528at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07211">
        <property type="entry name" value="Pat_PNPLA8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045217">
        <property type="entry name" value="PNPLA8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1350"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="8">
        <location>
            <begin position="687"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="157"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="607"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1188"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="5">
        <location>
            <begin position="691"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="5">
        <location>
            <begin position="723"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="5">
        <location>
            <begin position="918"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="725"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1412" mass="149853" checksum="7677E92B50F92308" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUU8</accession>
    <name>C1MUU8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P-type Cu(+) transporter</fullName>
            <ecNumber evidence="2">7.2.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_58940</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.8" evidence="2"/>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059255.1">
        <property type="nucleotide sequence ID" value="XM_003059209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUU8"/>
    <dbReference type="STRING" id="564608.C1MUU8"/>
    <dbReference type="GeneID" id="9685002"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58940"/>
    <dbReference type="eggNOG" id="KOG0207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ACGMNMV"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140581">
        <property type="term" value="F:P-type monovalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000001">
        <property type="entry name" value="ATPase copper transporting beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594:SF4">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="773"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="804"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="33"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH56387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="848" mass="90001" checksum="56FB0401F2CBED2D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVD0</accession>
    <name>C1MVD0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_69800</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059352.1">
        <property type="nucleotide sequence ID" value="XM_003059306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVD0"/>
    <dbReference type="GeneID" id="9685087"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69800"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912177" evidence="2">
        <location>
            <begin position="28"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="230" mass="23654" checksum="387594A3F117FF1F" modified="2009-05-26" version="1">MPRRSFVATETGCCAFTLIALFVEDAADPPPPPPPGEALPPLSRPPPRPRPRPPRGEGDACRGVPPCRGVDRADGGAVVVFSGPSASGGSTTAASPPRTAPAVRRSRSSRSPLARGDDDGAASTSTSTSPRLRTPSDVAAFVGDNAGDMTDGDGRGRRGSPRGRNGTPLAAARSIVRSTCATTTGRLLGGSATYARTPIESIDASVAVSRRRPIRQRGGLSARVVRRARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVM6</accession>
    <name>C1MVM6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65419</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059778.1">
        <property type="nucleotide sequence ID" value="XM_003059732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVM6"/>
    <dbReference type="GeneID" id="9685503"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65419"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="121" mass="13314" checksum="D61CE9923084C26F" modified="2009-05-26" version="1">MATDATKNAAKVWEAEQIETSRGSLDARRSRSLDRGASAARADARDDTRTPRDDQDDDDDHGLARRRDGITMTWRDLRYVVHPNGPSKPSKEVLRGLTGAALPRHVMALMGAFSRVVNAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWA6</accession>
    <name>C1MWA6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40696</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059891.1">
        <property type="nucleotide sequence ID" value="XM_003059845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWA6"/>
    <dbReference type="GeneID" id="9685620"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40696"/>
    <dbReference type="OMA" id="HAMAISW"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="630"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="974"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="673"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="704"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1083"/>
            <end position="1096"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1096" mass="108307" checksum="2CFE191D98AEDF1E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWX7</accession>
    <name>C1MWX7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AP2-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_6478</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059998.1">
        <property type="nucleotide sequence ID" value="XM_003059952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWX7"/>
    <dbReference type="STRING" id="564608.C1MWX7"/>
    <dbReference type="GeneID" id="9685163"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6478"/>
    <dbReference type="eggNOG" id="ENOG502QSBE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PWEAWIR"/>
    <dbReference type="OrthoDB" id="207175at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467:SF90">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR AIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00367">
        <property type="entry name" value="ETHRSPELEMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="6">
        <location>
            <begin position="7"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="6">
        <location>
            <begin position="108"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="168" mass="18603" checksum="D1E23C03FCFDFE0C" modified="2009-05-26" version="1" fragment="single">GKQRSSQYRGVTKHKRSGRWEAHIWVKETGKQMYLGGYDTEEHAAEAYDVAAMKCKGGAGNNGTRKVRLNFPAAKYAELSSFMASVSLEELVMAIRRQSQGFARGSSGFRGVTHHPNGRWEARIGMPGSKHIYLGLYNEEAAAARAYDRALVRLRGPGAATNYALVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY98</accession>
    <name>C1MY98_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40772</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060538.1">
        <property type="nucleotide sequence ID" value="XM_003060492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY98"/>
    <dbReference type="GeneID" id="9685704"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40772"/>
    <dbReference type="OMA" id="CAPRARQ"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="491"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="571" mass="60877" checksum="0AC775629F8DB130" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYP6</accession>
    <name>C1MYP6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59977</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060604.1">
        <property type="nucleotide sequence ID" value="XM_003060558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYP6"/>
    <dbReference type="GeneID" id="9685750"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59977"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="182" mass="20296" checksum="5BE5BFC258B31184" modified="2009-05-26" version="1">MRATREKNDDPRSYALAREDEERWAEAAERVVAWDEDSFSLSLPGDCGGASKPRAAADDRATTPPFARRWRRDDESAASRLAAYMRATGRLSKAAPLEDAVAATFFSSDAHATPRRARCRATLTTLDGERRVEDGRWAATEDDAKEDAMRALLAWMTMRDSTGVRPIHWFPYARVGAMNADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ97</accession>
    <name>C1MZ97_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60653</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060920.1">
        <property type="nucleotide sequence ID" value="XM_003060874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ97"/>
    <dbReference type="STRING" id="564608.C1MZ97"/>
    <dbReference type="GeneID" id="9686616"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60653"/>
    <dbReference type="eggNOG" id="ENOG502S25I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="536576at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36970:SF1">
        <property type="entry name" value="BESTROPHIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36970">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="340"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="492" mass="53949" checksum="FD41A604A200A3DD" modified="2009-05-26" version="1">MTPASDDLDVATPMVPPGSAHHKSTTSRGAGNGKVKRLDSYSLGDDVDDNLQRVDAMWAAESPLHVEWREGTPKTGPFAPLFGAVLALVASARVYFMFLVTVESILVSALSVASVLLFSLYKVHGNRLAVDVSWAFISFAIVFPLTNSLNEAFRRREEALRMIGEVKAYLLSYYQGHRDWDWGANGRGKLPAGHLSQVRYVVAQLVVDMRDVLTAPNTTRQEHFHTEWGRRQRMKMATIYREINQRIASHFDKISHAVEELKYGGMPGNESSRLRQYVTLTMCAWEKLKFIKKYRTPIATRAFARVYIFLHPIFWGPYYARLVEQMVGDDDASAGASSPSASLVVWANVYACTLAVLTSLAMMGLFNVRYNMEDPFCTDVRTAGGEMGGGGGAEAAGEKGGASTRSDRSSRAVGASQHISKGGMDLIHVNQEFAELMECVMKEATDAGANPCGGGPTARVWPVPELSKLAHVTFAAGVDVTRIAGDVDRQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZI0</accession>
    <name>C1MZI0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_70766</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061223.1">
        <property type="nucleotide sequence ID" value="XM_003061177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZI0"/>
    <dbReference type="GeneID" id="9686396"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70766"/>
    <dbReference type="OMA" id="YMTATAG"/>
    <dbReference type="OrthoDB" id="498677at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="151" mass="16384" checksum="8B075AFA4A66EA27" modified="2009-05-26" version="1">MSDTASIQFMITNAMKATLVDELEFRPEEVDVMRPEIAKELIEKKMKRPFGSKPMPEAWKRDYDPNKGGGGGGGGGLFGFLGPVGDLLRSVVYMSMTAGVALGVACAANGTVRKGVKGVVKDIKRTLKGKKRKKKKNRVRSNRGRGPSEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZN7</accession>
    <name>C1MZN7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63459</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061251.1">
        <property type="nucleotide sequence ID" value="XM_003061205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZN7"/>
    <dbReference type="GeneID" id="9686425"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63459"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="146" mass="15528" checksum="47A5E4B9B83DC673" modified="2009-05-26" version="1">MKDARRDEATTRAGTAATEGASRAPFFARSASAGTRACGSREGRCCCGGGTPCSRRSGHDAFKTGRPRRAKKPEELARARARSTRAAVTWPSTPRPARHNAPALSRTEAPPPTHARIARLLASPPPNTPCRFSDPSRPRSTARGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N021</accession>
    <name>C1N021_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin delta chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Delta-tubulin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_20062</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Acts as a positive regulator of hedgehog signaling and regulates ciliary function.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061320.1">
        <property type="nucleotide sequence ID" value="XM_003061274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N021"/>
    <dbReference type="STRING" id="564608.C1N021"/>
    <dbReference type="GeneID" id="9686759"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20062"/>
    <dbReference type="eggNOG" id="KOG1374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ACHPEYK"/>
    <dbReference type="OrthoDB" id="10250004at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02189">
        <property type="entry name" value="delta_zeta_tubulin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002967">
        <property type="entry name" value="Delta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01224">
        <property type="entry name" value="DELTATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="9 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 14" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="16">
        <location>
            <begin position="41"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH54970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="453" mass="48232" checksum="E8CFBE12954F46A7" modified="2009-05-26" version="1">MPGSVVTVQLGQCGNQVGCELFDTLAREAAASSPSVRDEIHEAFFRSGDGAARPSSSSSSSSSPTARAVLIDMEPKVIASSLKRARRSSHRWRYDANSALAFQSGSGNNWARGYNTYGGLVRDEALELVRREAERCDHLGGFLLTQSLAGGTGAGLGAFVAEAIRDEHRGATILNHCVWPYESGEVIVQCYNTLLTLSTLLNVSDGVCVVQNEQLHRACVGALKIKRPTFDDMNGVAATQLAGVLLPSVARGVTPAGGAGCGRKLMLLHDVSRGACCDPTMRLLSLRSVPMMPQTSVDFTTFAWPGLIKRARQMLLTGTTLEEGLDWGVEPGGDGGGRVVTRCLAAMAFLRGKGAEDADVGALSDPRLFPTWTPSPLSVSHSGARFCGYDASLTLLSNCQSACPPIGRMLARAYQMKHAGAYLHQYAEHGVGEGEFDEAFGRVEDVLAAYRAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N088</accession>
    <name>C1N088_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_41485</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061084.1">
        <property type="nucleotide sequence ID" value="XM_003061038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N088"/>
    <dbReference type="STRING" id="564608.C1N088"/>
    <dbReference type="GeneID" id="9686523"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41485"/>
    <dbReference type="eggNOG" id="ENOG502QT1A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ILIPQDW"/>
    <dbReference type="OrthoDB" id="2013293at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407:SF17">
        <property type="entry name" value="PSBP DOMAIN-CONTAINING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="2">
        <location>
            <begin position="94"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="265" mass="27642" checksum="4FB7F0504CB134C5" modified="2009-05-26" version="1">MSAAASSVTLARAVAAPRVAAKRHARVAGAVAPARCAAAASSSSSSSIDDASAASSSSSSSSSRAVDRRAVLLGGAALAATAAIAPDARAEGAETKRYVDAEDKYSFSVPADWEQAIGTTDDNPQSSRRVTAYFPPGDPDINVNVVCTALGADYPKMGSFGSPDEFAFGVAAGMTRPKPKSGPKQFSYVLNAKSKGDKYFIEYTVERPSEDFYQHLMSVVGVGYNGRVSRLITATAVCPEDKFAENKAKLEAILDTIELPPPLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0A3</accession>
    <name>C1N0A3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_45791</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH53992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061362.1">
        <property type="nucleotide sequence ID" value="XM_003061316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0A3"/>
    <dbReference type="STRING" id="564608.C1N0A3"/>
    <dbReference type="GeneID" id="9687037"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45791"/>
    <dbReference type="eggNOG" id="KOG0239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CTDWNSL"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14473">
        <property type="entry name" value="FERM_B-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01366">
        <property type="entry name" value="KISc_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000041">
        <property type="entry name" value="Kinesin-like calmodulin-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.530">
        <property type="entry name" value="MyTH4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019749">
        <property type="entry name" value="Band_41_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035963">
        <property type="entry name" value="FERM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019748">
        <property type="entry name" value="FERM_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002404">
        <property type="entry name" value="IRS_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000857">
        <property type="entry name" value="MyTH4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038185">
        <property type="entry name" value="MyTH4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF16">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00373">
        <property type="entry name" value="FERM_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02174">
        <property type="entry name" value="IRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00784">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00295">
        <property type="entry name" value="B41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47031">
        <property type="entry name" value="Second domain of FERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51016">
        <property type="entry name" value="MYTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MyTH4" evidence="11">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="FERM" evidence="9">
        <location>
            <begin position="135"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="713"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1061"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="518"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="577"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="795"/>
            <end position="802"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH53992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1084" mass="119645" checksum="984A025204A9BE7F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0F7</accession>
    <name>C1N0F7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_20162</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061384.1">
        <property type="nucleotide sequence ID" value="XM_003061338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0F7"/>
    <dbReference type="STRING" id="564608.C1N0F7"/>
    <dbReference type="GeneID" id="9687069"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20162"/>
    <dbReference type="eggNOG" id="KOG1252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DTSERYM"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000003">
        <property type="entry name" value="Cystathionine beta-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="5">
        <location>
            <begin position="51"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="399" mass="42525" checksum="23467E7152B0FAC5" modified="2009-05-26" version="1">MLASFTPALATQRASLRGRAVKPSPSRVAPPRSRPRAAALRTSAKLYENILETIGSTPIIKINKLAPEGVTMYAKAEFFNPCSSVKDRLALAVITDAERRGVLKPGDTVVEATSGNTGIAVAMVCAQRGYECVICMAEPFSVERRKIMRMLGAKVIVTPKAGKGTGMVAKAEELCEKHGWFLCSQFENDANPAFHASTTGPEILSDFAGKRLDYFVTGYGTGGTFQGVGRVLKAARPDVNIVLLEPEAAGLIASGTKTERKPTGAPKGSHPAFTPHPIQGWTPDFIPKVLEDAQAMNLYDELVPITGPESIETAQKLARMEGIFTGISGGASMAGALKVAANAPKGSVILTMLPDTSERYMSTPLYENIAADMDEAELEIAKSTPSFQLLPGEEPVLQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0X1</accession>
    <name>C1N0X1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_48266</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061468.1">
        <property type="nucleotide sequence ID" value="XM_003061422.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N0X1"/>
    <dbReference type="GeneID" id="9687149"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48266"/>
    <dbReference type="eggNOG" id="ENOG502QQ4F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PCEWFVQ"/>
    <dbReference type="OrthoDB" id="442692at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904158">
        <property type="term" value="P:axonemal central apparatus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033305">
        <property type="entry name" value="Hydin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053879">
        <property type="entry name" value="HYDIN_VesB_CFA65-like_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23053">
        <property type="entry name" value="DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23053:SF0">
        <property type="entry name" value="HYDROCEPHALUS-INDUCING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22544">
        <property type="entry name" value="HYDIN_VesB_CFA65-like_Ig"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14874">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HYDIN/VesB/CFA65-like Ig-like" evidence="7">
        <location>
            <begin position="220"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="HYDIN/VesB/CFA65-like Ig-like" evidence="7">
        <location>
            <begin position="507"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="HYDIN/VesB/CFA65-like Ig-like" evidence="7">
        <location>
            <begin position="1331"/>
            <end position="1425"/>
        </location>
    </feature>
    <feature type="domain" description="HYDIN/VesB/CFA65-like Ig-like" evidence="7">
        <location>
            <begin position="3038"/>
            <end position="3113"/>
        </location>
    </feature>
    <feature type="domain" description="HYDIN/VesB/CFA65-like Ig-like" evidence="7">
        <location>
            <begin position="4476"/>
            <end position="4572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1540"/>
            <end position="1571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1589"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1648"/>
            <end position="1717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2085"/>
            <end position="2137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2208"/>
            <end position="2244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2345"/>
            <end position="2408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2508"/>
            <end position="2577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2687"/>
            <end position="2725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2748"/>
            <end position="2767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2830"/>
            <end position="2877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2919"/>
            <end position="2964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="3196"/>
            <end position="3221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="3334"/>
            <end position="3353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="3671"/>
            <end position="3756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1648"/>
            <end position="1666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1693"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2114"/>
            <end position="2126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2218"/>
            <end position="2239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2351"/>
            <end position="2365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="2366"/>
            <end position="2377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2378"/>
            <end position="2406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2516"/>
            <end position="2536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2546"/>
            <end position="2574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2696"/>
            <end position="2710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2716"/>
            <end position="2725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2862"/>
            <end position="2877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2920"/>
            <end position="2929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="2938"/>
            <end position="2951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="3196"/>
            <end position="3205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="3343"/>
            <end position="3353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="3701"/>
            <end position="3710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="5081" mass="549296" checksum="F3F6912C8C0FA41E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N132</accession>
    <name>C1N132_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63001</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061738.1">
        <property type="nucleotide sequence ID" value="XM_003061692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N132"/>
    <dbReference type="GeneID" id="9686941"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63001"/>
    <dbReference type="OMA" id="RTHNDEM"/>
    <dbReference type="OrthoDB" id="10486679at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="193" mass="20288" checksum="505EA658DD597860" modified="2009-05-26" version="1">MGQKQKLREEKKASAASGVDCATLEKTSKAAYDRKNVAEVIARMKALAKEDTDRFAKMGLHETIERLEQSQKVAATIDAALAVEMTRKRALLGCFLSNEMTPPAPAAAAPTPTLHGAGVGDAVAKKTTAGGDGDDGEEEDEVANAKRQLAESQAEARRKLSVAKSTRTHNDEMVDALRAKGVTVPSEGVAAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1B9</accession>
    <name>C1N1B9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63058</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061540.1">
        <property type="nucleotide sequence ID" value="XM_003061494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1B9"/>
    <dbReference type="GeneID" id="9687225"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63058"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="296" mass="32837" checksum="7E9F76C3294BA402" modified="2009-05-26" version="1">MGRAARSRPSRRSTTRTTARAATSERRRGRSSAGTLNETRARSLVESSFSEDEQIDPIARAHRTTRPRHARSARMFNALTKASTLRRLSSAAAAVASRASAASETPRGLAASASALARERNPNRGAIGRVEANAATRHRAWTASPFLSAQQTRAYGPYHTKYPEAARPPDAWNDPDLRELDADGKEILPRNDYHVLNIPKHGTRNKWRRRREKAAFIQWNATVNRENRTKRNIERQEKRVEKWRTLAANARAYKARVEEEAAAAAAAAEAAEAERREEASEGGGPDEGARAKEGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1D0</accession>
    <name>C1N1D0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51353</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061545.1">
        <property type="nucleotide sequence ID" value="XM_003061499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1D0"/>
    <dbReference type="GeneID" id="9686985"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51353"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="606"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="683" mass="74753" checksum="3A274463BB9DDC9D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1P4</accession>
    <name>C1N1P4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_35551</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061950.1">
        <property type="nucleotide sequence ID" value="XM_003061904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1P4"/>
    <dbReference type="STRING" id="564608.C1N1P4"/>
    <dbReference type="GeneID" id="9687592"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35551"/>
    <dbReference type="eggNOG" id="ENOG502S8MQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RETHCAW"/>
    <dbReference type="OrthoDB" id="1934521at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051716">
        <property type="entry name" value="Plant_RL_S/T_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48053">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48053:SF71">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="470" mass="50084" checksum="41F12F441AD4DFF3" modified="2009-05-26" version="1">MWGWDGPDDEDLAFDVDAFDVDQVAETRRVERMVLTDLYRTTEGSRWYRQRGWLSRETHCAWEGVTCLRRSDPFGVLSLELRDNGLAGPLPQTLARLHKLRNLDLRDNALRGSVSSAFGSMTKLKVLLLKGNAVNGKLPKELGGAAGLTQADLSANAFIGAMPADLGRLSNLRMLNVSHNGLSGELPHRLCGAPSLEVLSASKNRIRGGLERCGAALDARGAASTMRLFDASENNFDGEPPAAPSRSGSLAIWDVSGNALTGTIPNRAPPRSLRVLSYARNKLTGAIPDALFPRDSGLRRVDLSGNALNGTLPDGLMGLTKVRVVNVSGNALSGAIPSEGDVDVRAMASLTDFDASNNALVGAVPPSLAGLKHLRTLSLRGNKLTGTIPCDQLAHSRSLRELDLSDNDLSGELSGDVAALGERLTRLDLSRNRLSGPVPVGLITGRALTHLDISGNEDLDWTSLGVREGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1Y3</accession>
    <name>C1N1Y3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51779</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061994.1">
        <property type="nucleotide sequence ID" value="XM_003061948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1Y3"/>
    <dbReference type="STRING" id="564608.C1N1Y3"/>
    <dbReference type="GeneID" id="9687637"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51779"/>
    <dbReference type="eggNOG" id="ENOG502RXIP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2020464at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040377">
        <property type="entry name" value="Ssl2009-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34048">
        <property type="entry name" value="LOW-DENSITY RECEPTOR-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34048:SF3">
        <property type="entry name" value="LOW-DENSITY RECEPTOR-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="144"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="202" mass="20848" checksum="9479C5E773952B69" modified="2009-05-26" version="1">MTSFASPTAPRARVVAAGANPRVARAASSSARVRARGASALGKKASEDRRPVAASASFALFSPSRTTTTTTTTTGRRGLTIVAKASDGGGNGGGVGKFLTGFLIGGAVCGVAGVLFAPQLSKTFLKGKDSVGKFLYEDYDEDDDDSLERTRRNLNDKIAQLNSAIDNFSTEADRGLSDKISKLNGEVEKLEKNAEGGAEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1N206</accession>
    <name>C1N206_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_51802</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062209.1">
        <property type="nucleotide sequence ID" value="XM_003062163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N206"/>
    <dbReference type="STRING" id="564608.C1N206"/>
    <dbReference type="GeneID" id="9687648"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51802"/>
    <dbReference type="eggNOG" id="KOG4205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="514262at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15241:SF304">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15241">
        <property type="entry name" value="TRANSFORMER-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="94"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="243"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="8">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="165"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="363"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="375"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="406" mass="42644" checksum="95CE4E6BEFACD944" modified="2009-05-26" version="1">MAKEDGDGGGDDDDAATAKEDAADARATTASANDPTDPTPPGTEEAEIMDDVAERIESPRRGVDPVDAAAAAAAAAPGPSPSTADDDDAETTPARLFVGNVAESIDPATFRARLEAFGDVASANLATKRGGRASRGFGFVTYASMASQRAALASDDVAFDVPNGGGARATWTVRVSQKPKSPGDTPREDGGDGEAGKTARGPADFDASSSRSKKDEKDTKPPPEGGAPRAGDQGPPTEKNPSVKYFVGGIGNTTFETLRAHFAKFGKIMACNVVHRTDGRPRGFGFVTFEREEDAEKALLEKHEVDGKTWDVKTVQPNSFVDSRGTKGVGGAVEGDWRCRRCDNVNFKWRDACFKCKHAPRFESGGGGGGGARRGGGDDRPRSRDGQVRSIHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N227</accession>
    <name>C1N227_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48454</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062016.1">
        <property type="nucleotide sequence ID" value="XM_003061970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N227"/>
    <dbReference type="STRING" id="564608.C1N227"/>
    <dbReference type="GeneID" id="9687659"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48454"/>
    <dbReference type="OMA" id="DRAPGYP"/>
    <dbReference type="OrthoDB" id="10690506at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="220"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="295"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="481"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="552"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="733"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="808"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="238"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="481"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="552"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="738"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="748"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="808"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="828"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="839" mass="83875" checksum="178C468E01B0C9B6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2V6</accession>
    <name>C1N2V6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucosylceramidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_48400</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061945.1">
        <property type="nucleotide sequence ID" value="XM_003061899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2V6"/>
    <dbReference type="STRING" id="564608.C1N2V6"/>
    <dbReference type="CAZy" id="GH116">
        <property type="family name" value="Glycoside Hydrolase Family 116"/>
    </dbReference>
    <dbReference type="GeneID" id="9687588"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48400"/>
    <dbReference type="eggNOG" id="KOG2119">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VMGEWAL"/>
    <dbReference type="OrthoDB" id="730489at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006775">
        <property type="entry name" value="GH116_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024462">
        <property type="entry name" value="GH116_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052566">
        <property type="entry name" value="Non-lysos_glucosylceramidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12654">
        <property type="entry name" value="BILE ACID BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12654:SF0">
        <property type="entry name" value="NON-LYSOSOMAL GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04685">
        <property type="entry name" value="DUF608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12215">
        <property type="entry name" value="Glyco_hydr_116N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912254" description="Glucosylceramidase" evidence="2">
        <location>
            <begin position="27"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl-hydrolase family 116 N-terminal" evidence="4">
        <location>
            <begin position="77"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl-hydrolase family 116 catalytic region" evidence="3">
        <location>
            <begin position="579"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="913"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="644"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1042"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1063"/>
            <end position="1073"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1073" mass="113127" checksum="01B04E3BDEE9324A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3E4</accession>
    <name>C1N3E4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_8595</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062365.1">
        <property type="nucleotide sequence ID" value="XM_003062319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3E4"/>
    <dbReference type="GeneID" id="9687805"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8595"/>
    <dbReference type="eggNOG" id="ENOG502RY61">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IGGPCVR"/>
    <dbReference type="OrthoDB" id="431169at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21618">
        <property type="entry name" value="RRM_AtNSRA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="17"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="107" mass="11576" checksum="8334256204F1D349" modified="2009-05-26" version="1" fragment="single">PGPGPRRGPPLPRDASPTLYIEGVPHDATVREIAHIFRPFDGFQSTRLVKKENVRGPLCFAEFAGADLAFAALNTLQGYVLDRDDPKSPALRIVFAKSKGRVPPGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3P6</accession>
    <name>C1N3P6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_48587</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062651.1">
        <property type="nucleotide sequence ID" value="XM_003062605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3P6"/>
    <dbReference type="STRING" id="564608.C1N3P6"/>
    <dbReference type="GeneID" id="9687851"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48587"/>
    <dbReference type="eggNOG" id="ENOG502QPTR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498039at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd04873">
        <property type="entry name" value="ACT_UUR-ACR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051258">
        <property type="entry name" value="Diverse_Substrate_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42920:SF26">
        <property type="entry name" value="OS03G0707200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42920">
        <property type="entry name" value="OS03G0707200 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="679"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="705"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="731"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="457"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="673"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="91"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH53470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="777" mass="82482" checksum="45CF90B5C3E897BE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3R9</accession>
    <name>C1N3R9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_68730</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062662.1">
        <property type="nucleotide sequence ID" value="XM_003062616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3R9"/>
    <dbReference type="STRING" id="564608.C1N3R9"/>
    <dbReference type="GeneID" id="9687863"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68730"/>
    <dbReference type="OMA" id="WWFEARN"/>
    <dbReference type="OrthoDB" id="498796at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="115"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="148"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="305" mass="32147" checksum="649809AF4A0DEE97" modified="2009-05-26" version="1">MAARARWCVAPPRAVPRRRAGGDAPGRARRRRGRGASAPRAADGPPPAEAASESIAVSTGRSASDDAKTELWERWWFEARNADALAVLAKMPGADVNRKTRPRIDPKGKVAFDPGGLTACALAAQRDDAASIRVLASLGADLNARDANGACALHHAAFADAADAADALVDLGADANAQDARDGSTAVILAAYGARRETLRRLVARHPVVDLSLRDVGNATVAGHCAQRRLADELLTILKLCGPGGAGRLLRGEKVYLGKRRELTGQLETLPARPHLAELCEAWGARVAEGDDKKALIAKLLQRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3Y4</accession>
    <name>C1N3Y4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_21635</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062695.1">
        <property type="nucleotide sequence ID" value="XM_003062649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3Y4"/>
    <dbReference type="STRING" id="564608.C1N3Y4"/>
    <dbReference type="MEROPS" id="S01.472"/>
    <dbReference type="GeneID" id="9687895"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21635"/>
    <dbReference type="eggNOG" id="KOG1320">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IMSPEGY"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00990">
        <property type="entry name" value="cpPDZ_AtDEGP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000001">
        <property type="entry name" value="Periplasmic serine protease DegS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051201">
        <property type="entry name" value="Chloro_Bact_Ser_Proteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039382">
        <property type="entry name" value="DEGP1/8_PDZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343:SF2">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343">
        <property type="entry name" value="PEPTIDASE S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="218"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="356"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="380" mass="39996" checksum="F969DA0D96FAD099" modified="2009-05-26" version="1">MRSLTSDEQATISLFKENTPSVVYITNLAQRRDVFTLNITEAPQGAGSGIVWDDDGHIITNYHVIARANQVRVTFQDQTVYPATVVGFDEDKDIANTSLKSASGKAEIRPVPLGTSSDLQVGQRVFAIGNPFGLDHTLTTGVISGLGREIQSGNTGRPIDGIIQTDAAINPGNSGGPLLDSAGRLIGINTAIYSTSGSSSGVGFALPSDMVSGIVSQIITSGRVTRPILGITFAPDQAVEQLGLGGVLVLDAREKGPAWRAGVKSTSRDESGRLILGDVIVELNGALIKNSSDLYRTLDKLTVGQEISMKVMRGENKVDLGLTLDDRPNEQSTQGMFIFPGMAPGEGIPIPPGGIPIPGLPGPGYEEDEDEGGQFLAPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4A5</accession>
    <name>C1N4A5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_70973</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062965.1">
        <property type="nucleotide sequence ID" value="XM_003062919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4A5"/>
    <dbReference type="STRING" id="564608.C1N4A5"/>
    <dbReference type="GeneID" id="9688405"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70973"/>
    <dbReference type="eggNOG" id="KOG2493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AWKTGNA"/>
    <dbReference type="OrthoDB" id="260807at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF80">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910750" description="Phosphate transporter" evidence="9">
        <location>
            <begin position="38"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="548"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="637"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="397"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="665" mass="69725" checksum="EE6BD1A2C2A9B51F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4H0</accession>
    <name>C1N4H0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PAF1 complex protein Leo1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42413</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062789.1">
        <property type="nucleotide sequence ID" value="XM_003062743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4H0"/>
    <dbReference type="STRING" id="564608.C1N4H0"/>
    <dbReference type="GeneID" id="9688229"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42413"/>
    <dbReference type="eggNOG" id="KOG2428">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NDWEDSN"/>
    <dbReference type="OrthoDB" id="498767at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990269">
        <property type="term" value="F:RNA polymerase II C-terminal domain phosphoserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007149">
        <property type="entry name" value="Leo1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23146">
        <property type="entry name" value="LEO1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23146:SF0">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN LEO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04004">
        <property type="entry name" value="Leo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="293" mass="31598" checksum="C17CD0D5F693DBF6" modified="2009-05-26" version="1">MATADLIKNVFGDSDSDSDADAAAPAAAAKPTKAELRATAAKKAAFAAALGAVDDDDDDDDAGGDASDDDGSLGGDVVAEKPAFRSSLEDPDAAGSDSDDEKPEPAPDLHIDVPYIDPIPEGVTAKIFKQTNVCRVEPQPYDPKTFQLETETITHADGTTETRPADVHNVIRWRHVLDEDGKQVMGEDGEPKIESNAKFVRWSDGSLTLHIGEEVLRVTETDMSGEHQYVYARHPGVLQGVKHIESRLQMAPRNLDSATHSRLTRRVDARHVKSKKVQARSPHTGSRTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4H8</accession>
    <name>C1N4H8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52561</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062793.1">
        <property type="nucleotide sequence ID" value="XM_003062747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4H8"/>
    <dbReference type="GeneID" id="9688441"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52561"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="126" mass="14415" checksum="E06F9614562FDBEF" modified="2009-05-26" version="1">MPASEREAVSFREIEDEALRLNAEAKETEEAGHFDDARALYERALELMSSTSGMTVPYATTLSNMACLLRTQKRYDEALELFTEALDMVENYQYWDSFGGEDSKKEMVDQILQNKLQMEIRSGVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4U2</accession>
    <name>C1N4U2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52681</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063055.1">
        <property type="nucleotide sequence ID" value="XM_003063009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4U2"/>
    <dbReference type="GeneID" id="9688293"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52681"/>
    <dbReference type="eggNOG" id="ENOG502QRNR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KQLAHAT"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="484"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="532" mass="54454" checksum="0DE770ACD50BCB9E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N582</accession>
    <name>C1N582_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flagella-associated protein FAP196-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_71081</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063125.1">
        <property type="nucleotide sequence ID" value="XM_003063079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N582"/>
    <dbReference type="STRING" id="564608.C1N582"/>
    <dbReference type="GeneID" id="9688565"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_71081"/>
    <dbReference type="eggNOG" id="KOG0266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RVWEMKS"/>
    <dbReference type="OrthoDB" id="10264376at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF39">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="356"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="448"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="490"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="589"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="630"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="669" mass="70300" checksum="1ECA9DD2D6C404E0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5F7</accession>
    <name>C1N5F7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_48896</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063353.1">
        <property type="nucleotide sequence ID" value="XM_003063307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5F7"/>
    <dbReference type="STRING" id="564608.C1N5F7"/>
    <dbReference type="GeneID" id="9688987"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48896"/>
    <dbReference type="eggNOG" id="KOG2211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MMVEYFE"/>
    <dbReference type="OrthoDB" id="18786at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019465">
        <property type="entry name" value="Cog5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048485">
        <property type="entry name" value="COG5_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049176">
        <property type="entry name" value="COG5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228:SF3">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20649">
        <property type="entry name" value="COG5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10392">
        <property type="entry name" value="COG5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 N-terminal" evidence="6">
        <location>
            <begin position="26"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="199"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="470"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="933" mass="97562" checksum="69BD0EFCB1FE19A3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5G0</accession>
    <name>C1N5G0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53325</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063355.1">
        <property type="nucleotide sequence ID" value="XM_003063309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5G0"/>
    <dbReference type="GeneID" id="9688988"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53325"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="73" mass="7810" checksum="4725258C8D3071EB" modified="2009-05-26" version="1">MSVAEIRMSVRVRPTPPGDPRAVNLDPRTGALALTTGEIFDYPSSVVVGSDQDVAYDALCAPLVRHQGLGFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5L9</accession>
    <name>C1N5L9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_63702</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063181.1">
        <property type="nucleotide sequence ID" value="XM_003063135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5L9"/>
    <dbReference type="GeneID" id="9688825"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63702"/>
    <dbReference type="eggNOG" id="ENOG502QVWK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GQNACKF"/>
    <dbReference type="OrthoDB" id="568028at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971:SF3">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="203"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="203"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="155"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="414"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="414"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="434"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH52317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="500" mass="53424" checksum="E9CCAF2FC1C2F7F1" modified="2009-05-26" version="1">MSSPPPPPPPPPRADSLVLLGVVVGRRNRSKRLAFFDLDVAGAGRGGGAFDAAEARSRVAAVVASASVDAPPPSSSASPPPPPLPSRVEIIAKTRAYNGGFEDDDALADARSRVLKLGNVVRARGRWTRRDDGEWSCACEGVELVSSWADANPGKHFSRAEEEGAAAAGGGGGGGGGGGAERRRDAPAASIDRTVVDDDDADPPPRPPCKFWLNQGVCHKGAACKYAHADDRGGRARAWIEARRARRRALAAEAGDPHGSDAVSKGKRAERFAEWLVRTFGVDALNAGDGVLDVAGGRGDVSFELYNRRGVKCTLVEPRARKLSKSQRKFLKNRPPSLGAADADAPLCAQVRAEFEPATWDRYANVSVIVGMHPDQATEAIADFALRRDVPFAVVPCCVFPRLFPRRVAVAVDAEEEEEDGEEEDGTPTVADEGAAHEAAGRSEEGRRRVSKQRTTEVTERRQLVEYLVNKTRGKMAFLDFEGANQVVYSTTPPSANERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N641</accession>
    <name>C1N641_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_8832</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063270.1">
        <property type="nucleotide sequence ID" value="XM_003063224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N641"/>
    <dbReference type="STRING" id="564608.C1N641"/>
    <dbReference type="GeneID" id="9688908"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8832"/>
    <dbReference type="OMA" id="NNAKVND"/>
    <dbReference type="OrthoDB" id="548600at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="5"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="38"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="72" mass="7781" checksum="2F26C117F9366E52" modified="2009-05-26" version="1" fragment="single">EDAKNGNRPLHIAAQNGFTHVCKLLIAKHAEIDATNAKNNTALHMALGYDYDECAEFLVNAGADPMIVNEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N650</accession>
    <name>C1N650_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63866</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063473.1">
        <property type="nucleotide sequence ID" value="XM_003063427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N650"/>
    <dbReference type="GeneID" id="9688715"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63866"/>
    <dbReference type="eggNOG" id="ENOG502R8W3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="208" mass="23564" checksum="65202F3799FAF031" modified="2009-05-26" version="1">MRQRKQPKKRLISVSSSVTLKPSSASSVTPSHATQVGGSMFAPPSRKPNPAAASFLRNTSTKRPADGPAGGLSAKDFLKRKQASANRSMMIDVQEAAKLGTVMGEDLRREEEEREKKKEREERELKRKQEQEEREARKLKEQEEKQRRIQRMMQEREQKKAQEAEKKRLREEERAAAAAAKRMRTASSPDQREGVATPSPDQEPIPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6K2</accession>
    <name>C1N6K2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_36490</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063753.1">
        <property type="nucleotide sequence ID" value="XM_003063707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6K2"/>
    <dbReference type="GeneID" id="9689002"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36490"/>
    <dbReference type="eggNOG" id="ENOG502RZCJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3426336at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20302">
        <property type="entry name" value="cupin_DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025979">
        <property type="entry name" value="ChrR-like_cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12973">
        <property type="entry name" value="Cupin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ChrR-like cupin" evidence="2">
        <location>
            <begin position="54"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="200" mass="22948" checksum="3F2886A9CF739924" modified="2009-05-26" version="1">MNDDERGGERQNEYDENQNSAHHAAAVVSSRLVHHPTRHVLQREEYVLPDVVVDDLVQTHDRLWVPQTETISFHPLLFNVSNGYYVNLLRVKGAGVLSRHKHPGAVHGWVLRGEWRYLEHDWVAKEGSYVFEPPGETHTLVVPEGCDEMITMFHVQGSLNYCDERGDVIKSEDVFDKLDMARKHYESVGLGASYVDNFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6Q0</accession>
    <name>C1N6Q0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53390</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063772.1">
        <property type="nucleotide sequence ID" value="XM_003063726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6Q0"/>
    <dbReference type="GeneID" id="9689031"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53390"/>
    <dbReference type="OrthoDB" id="10590856at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="116" mass="12588" checksum="89C48D88A0CB8869" modified="2009-05-26" version="1">MTFQIFVGGQRVNSDHITSTPAWADAQGKSRKRDAFEGDALDDELARANAHAGKRAFVSPQGGVQGDLMVAGGENPGGRQQRGHHLHVFQRPTRPLGELGCQVFVTPQQGGYDHPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6T4</accession>
    <name>C1N6T4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_53433</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Putative transcription factor.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063787.1">
        <property type="nucleotide sequence ID" value="XM_003063741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6T4"/>
    <dbReference type="STRING" id="564608.C1N6T4"/>
    <dbReference type="GeneID" id="9689050"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53433"/>
    <dbReference type="eggNOG" id="ENOG502QSPQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FGIKRWP"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044607">
        <property type="entry name" value="RKD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003035">
        <property type="entry name" value="RWP-RK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373">
        <property type="entry name" value="PROTEIN RKD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373:SF2">
        <property type="entry name" value="RWP-RK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02042">
        <property type="entry name" value="RWP-RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51519">
        <property type="entry name" value="RWP_RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RWP-RK" evidence="8">
        <location>
            <begin position="164"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="302"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="437"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="504"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="604"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="732" mass="76336" checksum="52EFFEE50E2E4CBB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7M0</accession>
    <name>C1N7M0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53751</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064120.1">
        <property type="nucleotide sequence ID" value="XM_003064074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7M0"/>
    <dbReference type="GeneID" id="9689369"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53751"/>
    <dbReference type="OrthoDB" id="2335338at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34957">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34957:SF1">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13474">
        <property type="entry name" value="SnoaL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="65" mass="7082" checksum="00D7CAC5AB554263" modified="2009-05-26" version="1">MERPLDVEAENVRVHASGDLGFVTCVEKVDSSTGYGTLTATNVFERQGGEWKMVHHHANGVQGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Q1</accession>
    <name>C1N7Q1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53786</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063947.1">
        <property type="nucleotide sequence ID" value="XM_003063901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Q1"/>
    <dbReference type="GeneID" id="9689573"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53786"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="809"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1078"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="458"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="739"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="824"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="848"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1078"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1122" mass="120772" checksum="1D31956B8BF9DF1F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7V0</accession>
    <name>C1N7V0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_53838</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063973.1">
        <property type="nucleotide sequence ID" value="XM_003063927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7V0"/>
    <dbReference type="STRING" id="564608.C1N7V0"/>
    <dbReference type="GeneID" id="9689414"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53838"/>
    <dbReference type="eggNOG" id="KOG0272">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CRGHKDE"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050349">
        <property type="entry name" value="WD_LIS1/nudF_dynein_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44129">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="67"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="390" mass="39674" checksum="C68E789023466EB1" modified="2009-05-26" version="1">MGSPNVPLVLQNGAMRKGVDRAHFGRVFDIAFCPWDDRLFASAGEDETARVWLDRGAADGATAHGVCRGHKDEVVRVAWHPTLKILATGSADGASGVWRIAQPGAEESANANDPNAGAIALVDTLVDETCGDEVYGCAFVGECGDGPVLATASGADVRLWDLESGGMTCRATPSAATSAAASAGAVPERWRPGYLFSLASDGGARGLLASGCSDGRVRVYAHDSTAGTVTNVACLPLHANAMVSCTAFLAGGDVLASVSADGVVVTTDVRTMTATRRITAPCPIMGCCAIGGVDGNWLAMCGNDGVVRAMDVTGEGGSKSMRVSESPLLCVAADARGKRIAAAGHQAEAAQKSVGSFGWSESSGGGVFGAKKKPSPAVVHLFESAGDVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N893</accession>
    <name>C1N893_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_43272</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064042.1">
        <property type="nucleotide sequence ID" value="XM_003063996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N893"/>
    <dbReference type="STRING" id="564608.C1N893"/>
    <dbReference type="GeneID" id="9689670"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43272"/>
    <dbReference type="eggNOG" id="KOG2425">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498994at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090730">
        <property type="term" value="C:Las1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007174">
        <property type="entry name" value="Las1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002:SF0">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04031">
        <property type="entry name" value="Las1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="149" mass="16609" checksum="25FFF6C4298D5609" modified="2009-05-26" version="1">MSARRVPWKDWDEWEWVRAGVSGHDVALRDRALRRVEEWRTFQGHVPHAVEVTAQLMEARQMDRGVPGAPGPFVSESMLRLTYAMALVRMVNGCVDPSQNGKYAAPVMTLAKKIGIPVLLVNVRMEASHQALPQVRSSHTGSHTTASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8L6</accession>
    <name>C1N8L6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_11591</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064287.1">
        <property type="nucleotide sequence ID" value="XM_003064241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8L6"/>
    <dbReference type="STRING" id="564608.C1N8L6"/>
    <dbReference type="GeneID" id="9689728"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11591"/>
    <dbReference type="OMA" id="WDDAIVY"/>
    <dbReference type="OrthoDB" id="6288734at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009143">
        <property type="term" value="P:nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="RdgB/HAM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067:SF9">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="124" mass="13648" checksum="5D23AA653F265BE9" modified="2009-05-26" version="1" fragment="single">LVFVTGNTGKLTRARLALSLRSLSRVQVQGVDLKIPEIQADSVKAVAMDKARRAFEELKRPLIVHDCGLVCAALKDFPGPATKYANYTIGTEGLLNLMREKEDRRAGWADVIVHVDANGKLKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N902</accession>
    <name>C1N902_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_45062</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="5"/>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064529.1">
        <property type="nucleotide sequence ID" value="XM_003064483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N902"/>
    <dbReference type="STRING" id="564608.C1N902"/>
    <dbReference type="GeneID" id="9689813"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45062"/>
    <dbReference type="eggNOG" id="KOG2472">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FPGRCAN"/>
    <dbReference type="OrthoDB" id="1698572at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000005">
        <property type="entry name" value="Phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000059">
        <property type="entry name" value="phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.40.10:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="entry name" value="Phenylalanyl-trna Synthetase, Chain B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004531">
        <property type="entry name" value="Phe-tRNA-synth_IIc_bsu_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040659">
        <property type="entry name" value="PhetRS_B1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00471">
        <property type="entry name" value="pheT_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947:SF0">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18262">
        <property type="entry name" value="PhetRS_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56037">
        <property type="entry name" value="PheT/TilS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B5" evidence="16">
        <location>
            <begin position="299"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH51434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="595" mass="65570" checksum="D5707FF7306C30F3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9F3</accession>
    <name>C1N9F3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_54485</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064611.1">
        <property type="nucleotide sequence ID" value="XM_003064565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9F3"/>
    <dbReference type="STRING" id="564608.C1N9F3"/>
    <dbReference type="GeneID" id="9689882"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54485"/>
    <dbReference type="eggNOG" id="KOG2159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="445712at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3090.10">
        <property type="entry name" value="cca-adding enzyme, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052191">
        <property type="entry name" value="tRNA_ntf/polyA_polymerase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43051">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43051:SF1">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAP" evidence="6">
        <location>
            <begin position="179"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="99"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="229"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="457"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="277"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="457"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="500"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="787" mass="86053" checksum="22751236FA00CEFF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Q9</accession>
    <name>C1N9Q9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_54588</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064779.1">
        <property type="nucleotide sequence ID" value="XM_003064733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Q9"/>
    <dbReference type="STRING" id="564608.C1N9Q9"/>
    <dbReference type="GeneID" id="9690220"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54588"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HCEMEGA"/>
    <dbReference type="OrthoDB" id="42736at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="535"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="644"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="679"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="750"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="15"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="59"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="844" mass="89872" checksum="F4F91844054E2DE0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGX0</accession>
    <name>C1MGX0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA topoisomerase 1</fullName>
            <ecNumber evidence="3">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TOP1</name>
        <name evidence="13" type="ORF">MICPUCDRAFT_49968</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054849.1">
        <property type="nucleotide sequence ID" value="XM_003054803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGX0"/>
    <dbReference type="STRING" id="564608.C1MGX0"/>
    <dbReference type="GeneID" id="9680876"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49968"/>
    <dbReference type="eggNOG" id="KOG0981">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RKHEYED"/>
    <dbReference type="OrthoDB" id="47179at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00660">
        <property type="entry name" value="Topoisomer_IB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.15.10:FF:000003">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.11.10">
        <property type="entry name" value="DNA Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.15.10">
        <property type="entry name" value="Topoisomerase I, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.41">
        <property type="entry name" value="Yeast DNA topoisomerase - domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013034">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013030">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001631">
        <property type="entry name" value="TopoI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025834">
        <property type="entry name" value="TopoI_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014711">
        <property type="entry name" value="TopoI_cat_a-hlx-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014727">
        <property type="entry name" value="TopoI_cat_a/b-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008336">
        <property type="entry name" value="TopoI_DNA-bd_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013499">
        <property type="entry name" value="TopoI_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018521">
        <property type="entry name" value="TopoIB_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14370">
        <property type="entry name" value="Topo_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02919">
        <property type="entry name" value="Topoisom_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00416">
        <property type="entry name" value="EUTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00435">
        <property type="entry name" value="TOPEUc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00176">
        <property type="entry name" value="TOPO_IB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52038">
        <property type="entry name" value="TOPO_IB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="DNA topoisomerase I eukaryotic-type" evidence="12">
        <location>
            <begin position="306"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="584"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="119"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="9">
        <location>
            <position position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH60101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="685" mass="76593" checksum="C6BEF56416C1DBCE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH01</accession>
    <name>C1MH01_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50001</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055408.1">
        <property type="nucleotide sequence ID" value="XM_003055362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH01"/>
    <dbReference type="GeneID" id="9680891"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50001"/>
    <dbReference type="OrthoDB" id="10636243at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="278" mass="30799" checksum="7C910678D5ABA79B" modified="2009-05-26" version="1">MGARRRQQRASASTDAASDATATKEKAAAIRRKKRADEFRLYLNLLKAFLCGVVLVMMSTAAMWYGGKGKYSRLARREAELSEAVRKMEANPELAKAREMLKTQHAIGLGTIRGGMDADDDVIASLESKWIAMDYAERSELWRGTRATLAETDPAFAPLLKADGKKLTDAVVPEIFAVDEFSEDAGRFPRLVRLVLEGKETGGQWRTKDGEDGTDRDRAGRREPTADHIVARDLYRRALLSRFVGAVANALRGGDYVVDVAALARELGRQIPSIRREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH14</accession>
    <name>C1MH14_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50013</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054873.1">
        <property type="nucleotide sequence ID" value="XM_003054827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH14"/>
    <dbReference type="STRING" id="564608.C1MH14"/>
    <dbReference type="GeneID" id="9680810"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50013"/>
    <dbReference type="eggNOG" id="KOG4408">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QWMANEP"/>
    <dbReference type="OrthoDB" id="2305498at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1470">
        <property type="entry name" value="ApaG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050718">
        <property type="entry name" value="ApaG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007474">
        <property type="entry name" value="ApaG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036767">
        <property type="entry name" value="ApaG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47191">
        <property type="entry name" value="OS05G0170800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47191:SF2">
        <property type="entry name" value="OS05G0170800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04379">
        <property type="entry name" value="DUF525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110069">
        <property type="entry name" value="ApaG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51087">
        <property type="entry name" value="APAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApaG" evidence="2">
        <location>
            <begin position="112"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="283" mass="30382" checksum="FEC55D8C93E10CE1" modified="2009-05-26" version="1">MNVARVAYRGLLRATRRLDQQLARHGTVDVFPENECARLRELLPGYKIALAPNSRAALRALVGDAFRAGARLDARAHAVDVGRRLDDAIAAYALLNRRLALLESMAADVSSDTLTSGVRVRVRSALLPEMSDPREGEFWYSYTVVVKNESVDEPVQVVSRRWEIRDEEGRVQDVLGVGLVGFQPVLERGAEFEYTSRVSLERLKGTMSGDFTVVGQRSGALWEAVVGAFALSPPRAPTANAAAADADAAREGGGASGAKGKGRGGRAKKAAEVVNKAATAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH27</accession>
    <name>C1MH27_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_30709</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055421.1">
        <property type="nucleotide sequence ID" value="XM_003055375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH27"/>
    <dbReference type="STRING" id="564608.C1MH27"/>
    <dbReference type="GeneID" id="9680441"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30709"/>
    <dbReference type="eggNOG" id="KOG0029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MELLYYY"/>
    <dbReference type="OrthoDB" id="2219495at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF46">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="74"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="598" mass="64138" checksum="B7E978B29556D3E7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH55</accession>
    <name>C1MH55_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50056</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055436.1">
        <property type="nucleotide sequence ID" value="XM_003055390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH55"/>
    <dbReference type="GeneID" id="9681216"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50056"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="114" mass="13129" checksum="93B3A40EFB33EC85" modified="2009-05-26" version="1">MGYYDPEEAPVAGMPSGRNKVDRRQLPPQQHEFNQRMMRATGEESPKPFHFEHPKDVSKICVERDVFGRPVLSPKIKLSFNGEDGDTTPVKSPAVKNAELREVRGELDYRSRFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHF1</accession>
    <name>C1MHF1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61319</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055480.1">
        <property type="nucleotide sequence ID" value="XM_003055434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHF1"/>
    <dbReference type="GeneID" id="9680327"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61319"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="386" mass="41017" checksum="0FC11B0C4F9D563A" modified="2009-05-26" version="1">MSPIVKEVTPLLERKPARKWPIVTAVASVAIVGTLGAILVFSRTNTFQSNSASALGLTPAEVEAQYVAMENAGPDFNWKPCGVCPTPSDILSCPPCMIGGLRGRCVDVGVCQTTDIQVVGSNPLDAYVHTTSDEDDEKYMEMENAGPDFKWYPCPACAGSQADGRSTCAPCLNDNERGRCGPAVGQCTVNSAPVMSAPTYVPLESPMPAPRLSVAPWGNRRMCATTEEKQHGHRGLTDGQTCYLEQWGPDASGAWVRIRDARGRCVEINEDTPPTTPGMSTSASYPTMGMSYAFCLDDRRCKTREQKQAGMPGPGPGRGCMWPFVMGQPGRCVDSPYDEAVGGYCQWNNPHFTTPPGCTGPSCTGARLGVAAKEAAAGGPGLHAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHG1</accession>
    <name>C1MHG1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_12472</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055485.1">
        <property type="nucleotide sequence ID" value="XM_003055439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHG1"/>
    <dbReference type="STRING" id="564608.C1MHG1"/>
    <dbReference type="GeneID" id="9680220"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12472"/>
    <dbReference type="eggNOG" id="ENOG502RXGP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SECLTVR"/>
    <dbReference type="OrthoDB" id="185175at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13276">
        <property type="entry name" value="PH_AtPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000286">
        <property type="entry name" value="PH-protein kinase domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051707">
        <property type="entry name" value="PI-Interact_SigTrans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336:SF8">
        <property type="entry name" value="PROTEIN OPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336">
        <property type="entry name" value="TANDEM PH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="28"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="142" mass="16275" checksum="057E73E70D38F351" modified="2009-05-26" version="1">MDKIFSSFSTLLNPSQAELTAGISFWQDAVHAGWLEKQGDVIKTWRKRWFVLKDNKLFWFLDDDVQQCSRVRGVIDVSKCMSVKGCDDAFGREHCFELSTRNEQMYFVCATKADKEGWLSCLGKAVVSTSRDTDGFTEYLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHH4</accession>
    <name>C1MHH4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cilia- and flagella-associated protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_37894</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CFAP45 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055494.1">
        <property type="nucleotide sequence ID" value="XM_003055448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHH4"/>
    <dbReference type="STRING" id="564608.C1MHH4"/>
    <dbReference type="GeneID" id="9680677"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37894"/>
    <dbReference type="eggNOG" id="ENOG502QPRZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WGHKPET"/>
    <dbReference type="OrthoDB" id="1902038at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033253">
        <property type="entry name" value="CFAP45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043597">
        <property type="entry name" value="TPH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15504:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15504">
        <property type="entry name" value="NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13868">
        <property type="entry name" value="TPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trichohyalin-plectin-homology" evidence="9">
        <location>
            <begin position="149"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="89"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="509" mass="59093" checksum="200BBE6C43809C68" modified="2009-05-26" version="1">MPRPLPNLRSTYRSKPSSVDESLFGTKKSSSASTNSFQRKTAKPSTASSAAKSTKSSAGSDYLVLSSNDIDRMRKPASVLTPHEVSAIKAERQAEKELELMKSKQMRERMSTMEARRGGASKGKEPSETEVIAAAKSQSTLNRAELLREEALDEVKNMNQMMLYSKCVTIRDAQLEEKKHILAEAQEEERRMDLMMEIERMKALDVYEEREKQRAEDRMKGAAVLRKQIEDRAKERAREEELLDLDRKQMLSEIQRVKDEAAAEAQRKRDMGKKLLAEVSKANAAQIERKKLIIQAERDEEERIAQYIADRDARELAEQMERDRVAHEKEMETVRMRAQQEKQADTQAEMDELRAMRVQEAHERAYREKERAAVARNRAINEDLARAREHQKMLKMKQLSDQARQDQSEFFRVVDVQMAKEEEEAQQSARLAALRKQHKEELQAQINFNEERRLHERREFLEEGDSLRKNMMDEQARLESIKQRKLDELSRTGVPTKYLAELARKKINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI41</accession>
    <name>C1MI41_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50428</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055601.1">
        <property type="nucleotide sequence ID" value="XM_003055555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI41"/>
    <dbReference type="STRING" id="564608.C1MI41"/>
    <dbReference type="GeneID" id="9680265"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50428"/>
    <dbReference type="eggNOG" id="KOG4232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HGRGKWC"/>
    <dbReference type="OrthoDB" id="260091at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF19">
        <property type="entry name" value="DELTA(5) FATTY ACID DESATURASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="109"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="508" mass="56730" checksum="0244F95A87908506" modified="2009-05-26" version="1">MTSSSAVASAASAATHAMRAAARPRASSRGASSAPRRAAVAPAVPGSASSSRDDGIVVRRRAIALRRRSPMTPHPAFLSPFETAVADAPASDAASAKKKKTKGALRLRIDGEWYDCTGWAKAHPGGSLFITLMDGCDATDVFYALHSYGPNGDDLAARRLAMLPRCDGPEEEEEEEEEEEGGREIAAPSIVRNPNHTIETKPGNADANFATLRKKFEDEGWFARDPLKEASVLCQVLGLYALGWFLAWTHPILASLSLGLGMQQAGWLAHDYIHGRGKWCTMMRGFGSLTNGFSTEWWQHKHNMHHSFTNIDGRDGDIKLEPLYYLQDPKVTGRNDNPGLRKWQHWYGYPLYAATYALWRRHSMASAIARRDKKELTLLGIHYAWLFLCLPWQVAVSSVLIGGFLVGSLVTATHQTEEIMFEQGGEFVDIQFRSTREADVKGLEAWLWGGMDTQLVHHLFPTMPRYRHHEARPVIRKWAEEHGYDFRISSSWEILSKNFNHLKELAHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI75</accession>
    <name>C1MI75_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_50464</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055078.1">
        <property type="nucleotide sequence ID" value="XM_003055032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI75"/>
    <dbReference type="STRING" id="564608.C1MI75"/>
    <dbReference type="GeneID" id="9680824"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50464"/>
    <dbReference type="eggNOG" id="KOG4359">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LHMHAFA"/>
    <dbReference type="OrthoDB" id="1915375at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486:SF5">
        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486">
        <property type="entry name" value="APRATAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="203" mass="22231" checksum="09216CB45AB6A815" modified="2009-05-26" version="1">MGLTAWTYELFQSWNILPKDDRVARPKTCEFCAKIASSARDETFVHADDALVVFEDWKPAAARHYLVCPREHITSANALSGAGRREGDDDGGDGDRARGGGGDAAMARRMLELGKEAIARDYADATTTPDTKFGFHLPPFNSVDHLHMHAFALPFDPPWKEHKYGGVLGSVAFAEATDVIERLEREEAEAAAAEAEAGRRSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MII4</accession>
    <name>C1MII4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MYT1</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_13156</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055672.1">
        <property type="nucleotide sequence ID" value="XM_003055626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MII4"/>
    <dbReference type="STRING" id="564608.C1MII4"/>
    <dbReference type="GeneID" id="9680857"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13156"/>
    <dbReference type="eggNOG" id="KOG0601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SKDHSPC"/>
    <dbReference type="OrthoDB" id="1335080at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF185">
        <property type="entry name" value="WEE1-LIKE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="8"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="300" mass="32129" checksum="675F9B68232133D5" modified="2009-05-26" version="1">MSRLRTDFVDVGVVGRGGFCKVFKVIGRLDGAQYAVKRTEKKLQTEREKLEALREVQAMASLGGGGEHVVRYFGAWMEYDHLYIQLELCDGTLSELSALSNAATEASLVSGVPVPAGVKIFDEAAVIEVLTHVCRALRYAHARNVAHLDVKPDNVLHRRGAYKLADWGRAAPVDGIGGGRLVSVEEGDARYLAPELLRGDFGCSLGVPGDSSFVGLDRADVFSLGATAYELARRAPLPSSGDEYQALRRGVGVRPLGEGWSDGFHALISSMMREAPGERPSAKRLMREGLLSGDGGGGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIR4</accession>
    <name>C1MIR4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50667</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055176.1">
        <property type="nucleotide sequence ID" value="XM_003055130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIR4"/>
    <dbReference type="STRING" id="564608.C1MIR4"/>
    <dbReference type="GeneID" id="9680734"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50667"/>
    <dbReference type="OMA" id="IHGVDQR"/>
    <dbReference type="OrthoDB" id="46564at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="34963" checksum="4EAFC9507E3A34E6" modified="2009-05-26" version="1">MSDDADDVAAKEAAALFKIHGVDQRSPSLTFEHAALGDGVVVAVRQDGSTSRSFLPGTSTVIWPCAYTLADILCDATAAWRRTREEEECASVVGGVDGDAAAIDAATDGAVTPHTVVVELGAGLGLAGLACAALGAKRVAITDATTAAAERNVRASGLENATVHELWWRRAGWRRRRGRGAAAAPATADESKSKSKSESESESESESDVDEEPEGTPTAAEVAEALLKTLPGGEAPHMIIGSDVCYSQSRGEMQMLADTMSALAAPGRTKIFVVFEDRGDCCWGTLNHFWVAAEKAGLEGDPTPVDELKTRAGEGRHNDSERLLLTLTKRASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJG2</accession>
    <name>C1MJG2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50928</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055828.1">
        <property type="nucleotide sequence ID" value="XM_003055782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJG2"/>
    <dbReference type="STRING" id="564608.C1MJG2"/>
    <dbReference type="GeneID" id="9680531"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50928"/>
    <dbReference type="eggNOG" id="ENOG502RZCC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="497540at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH61080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="437" mass="48682" checksum="C17D7ACB99F2767D" modified="2009-05-26" version="1">MAPPKRRRSARLAVDDDDRSTDDRSTDDLRRENADLRREIAALEEELRSLREAARSPSILERFVEEAPDVFAAHVLPRFDNYGDLAVLAMVNRQMRGVVFELPVGDVRWTGAAVSRELAKVRNFVGSIRRLAWAWERGCPWNAKTFACIAKGGNLEVAKWAKERGCQWDERTCAEAAGEGHLEVLQWLRANGCPWNEWTCFHAAMGGHFEVLKWARANGALWDENTCSSAAWSGDLQILQWARANGCPWDGETCSEAAIHGHLELLQWARANGCPWDESTCSRAAEGEELEVLKWARANGCPWDTKTCAEAACGGQLEMLQWARANGAPWDEETCSKAAEGEDLEVLKWARENGCPWDTKTCAEAATGGQLEMLQWARANGAPWDEETCSKAAEGNELEVLQWARANGCPWDKETCKKAEEGGHLEVLRWAGENGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJH8</accession>
    <name>C1MJH8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_65216</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056215.1">
        <property type="nucleotide sequence ID" value="XM_003056169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJH8"/>
    <dbReference type="STRING" id="564608.C1MJH8"/>
    <dbReference type="GeneID" id="9682065"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65216"/>
    <dbReference type="OrthoDB" id="2160585at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="642"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="642"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="601"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="675"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="601"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="737" mass="75916" checksum="8BD17E9B0ECDDC9D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJN7</accession>
    <name>C1MJN7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55035</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056244.1">
        <property type="nucleotide sequence ID" value="XM_003056198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJN7"/>
    <dbReference type="GeneID" id="9681629"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55035"/>
    <dbReference type="OrthoDB" id="194076at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050744">
        <property type="entry name" value="AI-2_Isomerase_LsrG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33336:SF1">
        <property type="entry name" value="(4S)-4-HYDROXY-5-PHOSPHONOOXYPENTANE-2,3-DIONE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33336">
        <property type="entry name" value="QUINOL MONOOXYGENASE YGIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="170" mass="19210" checksum="E4F7E479F4E7DD5F" modified="2009-05-26" version="1">MHIAHVHVHVKPGMEDEFVDACVANAASSVLEPDNLRFDVLRSGAFYHLDHLALDFYTSRRLFLSAHHPSLLSIPTHAPRRLSTPPLTPFNSTPTFVASYGRSPSEEDPTRFVLIEIYATAEGPAAHKKTPHYAEWRTTVEDMMASPRSARTFRPVFPTEVDEWKMALWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJW3</accession>
    <name>C1MJW3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">S-acyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_55124</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056280.1">
        <property type="nucleotide sequence ID" value="XM_003056234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJW3"/>
    <dbReference type="STRING" id="564608.C1MJW3"/>
    <dbReference type="GeneID" id="9681291"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55124"/>
    <dbReference type="eggNOG" id="KOG1311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4096362at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="10">
        <location>
            <begin position="359"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="479"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH59656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="548" mass="60053" checksum="95C0EE203B421457" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK17</accession>
    <name>C1MK17_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_46515</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056313.1">
        <property type="nucleotide sequence ID" value="XM_003056267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK17"/>
    <dbReference type="STRING" id="564608.C1MK17"/>
    <dbReference type="GeneID" id="9681301"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46515"/>
    <dbReference type="eggNOG" id="KOG0323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LRWHMDY"/>
    <dbReference type="OrthoDB" id="498964at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="8">
        <location>
            <begin position="441"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="156"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="582"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="739"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="772"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="624"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="634"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="645"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="798" mass="86053" checksum="26765CD0E234473D" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK35</accession>
    <name>C1MK35_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64190</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056321.1">
        <property type="nucleotide sequence ID" value="XM_003056275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK35"/>
    <dbReference type="GeneID" id="9681462"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64190"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="303" mass="32794" checksum="AE9439C4E8A37FFF" modified="2009-05-26" version="1">MKLLRSSAKARAQSSHSLQFTTRLKSGMLAWQGATKNNFHRGCGASLASRWAAKKRALCDAEETAREEGFQSEDESSRVREAGNKRTRHFAKPLDTSLDVLDIVLLRHEATEALEATIATAATNTTNEANTAGEEACSKKNVDCAALALTPYMRPSRPSSGPFIATIPSVCIISPAAAESSLDLCGDLSLTARARGAEEEATAEEEAKARQSAVATAATQAALHNPRRLLFASDDGDDKREDETEEVTSRGGDFDLDLVRTQLCACSSPLRALADVMCSPRTGARMFLFSDAWMVEEEEEEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK88</accession>
    <name>C1MK88_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_3089</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056343.1">
        <property type="nucleotide sequence ID" value="XM_003056297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK88"/>
    <dbReference type="STRING" id="564608.C1MK88"/>
    <dbReference type="GeneID" id="9681676"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3089"/>
    <dbReference type="eggNOG" id="KOG0234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RWIQERC"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="428" mass="49547" checksum="3BD99BFF151A7F74" modified="2009-05-26" version="1" fragment="single">HVLVMVGLPARGKTHMAKRLCQYLRFFHGARTQVFNVGSYRRKMMPAGRKADAKFFDQSDAESEKTRKEFARAALKDMIDFLFQSDVASCLEQRGFDSGRVAIFDATNTTRARREWIRKELHGLPLKLLFIESVCTDEQVIDRNIWHVKVQNEDYSDDADKRRAFDDFKLRIAHYEKVYEPMDEEHLSYIKLINQGRRVEINNIHGFLLGRIVQFLSNLHATHQTIYLCRHGQSEYNFLGKIGGDSGLSPMGEAFATKLGEYCEREIATDPETREPRPCRLWTSSLRRTILTGRHIPHPKIRTKDGENWIQMAPRVLRNLDEIYAGVCDGMTYEEIEVNYPEEFALRRENKLSYRYPRGESYLDVISRLDPLVQELESYQEPVLIIGHQGVLRLIYAYFTGMDRADACTASIPLNAVITLTPKTHTCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKV9</accession>
    <name>C1MKV9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NTF2-related export protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Ntf2</name>
        <name evidence="4" type="ORF">MICPUCDRAFT_49446</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056455.1">
        <property type="nucleotide sequence ID" value="XM_003056409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKV9"/>
    <dbReference type="STRING" id="564608.C1MKV9"/>
    <dbReference type="GeneID" id="9681368"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49446"/>
    <dbReference type="eggNOG" id="KOG2104">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QFVEYYY"/>
    <dbReference type="OrthoDB" id="6507044at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000005">
        <property type="entry name" value="Nuclear transport factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="3">
        <location>
            <begin position="14"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="136" mass="15118" checksum="594C912386B58D16" modified="2009-05-26" version="1">MDPLANVCSNFEQVGQAFVSHYYNTFDANRSHLGQLYKDEVSMLNFEHSAERPGQYKGVSAILSKIQSLPFQQVKHHVITIDCQPTPGGGVIVMVCGNLLVDAEQIPQKFSQVFQLLPSGNGSFYILNDIFRLNIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKZ5</accession>
    <name>C1MKZ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55517</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056471.1">
        <property type="nucleotide sequence ID" value="XM_003056425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKZ5"/>
    <dbReference type="STRING" id="564608.C1MKZ5"/>
    <dbReference type="GeneID" id="9681544"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55517"/>
    <dbReference type="eggNOG" id="ENOG502QVK7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THQNASI"/>
    <dbReference type="OrthoDB" id="2020701at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407:SF3">
        <property type="entry name" value="PSBP DOMAIN-CONTAINING PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="1">
        <location>
            <begin position="104"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="279" mass="30755" checksum="081413BFE5052817" modified="2009-05-26" version="1">MQLRSLCVQVRGGFHVASNLFRTHQNASITATCGLKNEKFPVSRLYSSVQNSTVAQSKSLDGGGSGNAYSMCRRDFFGYFMVCLGENRELFTPRALACSTVPGKFTVFVDRINLFSLCYPMEWEILNKAGAKLFLRDSADNNSQVGVTVNPVKISTLSEFGSVHDVGERLVAAEATKESTLPGGVTLIREGSRQGPRSGSTFYDYEYQLTTTRGKKLVFNTVAVDNNLLYILNIQVKERIFSGQENDKSMIDDVVAGFRTLIQTFDVGQSTIDVSSQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLM1</accession>
    <name>C1MLM1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_7177</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056190.1">
        <property type="nucleotide sequence ID" value="XM_003056144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLM1"/>
    <dbReference type="STRING" id="564608.C1MLM1"/>
    <dbReference type="GeneID" id="9681805"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7177"/>
    <dbReference type="eggNOG" id="KOG3215">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WANSKND"/>
    <dbReference type="OrthoDB" id="205166at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008501">
        <property type="entry name" value="THOC7/Mft1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05615">
        <property type="entry name" value="THOC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="97"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="189" mass="21380" checksum="8639CB835EA260DB" modified="2009-05-26" version="1" fragment="single">KDDENFIRSRLRTQTATARPGADPPLKKLLKKYVVYFDALASGGREDKMANDAQKEAFLKDSVNFDLAMARTTSVVSANSGEMDAYRVDHGNVRTSISNAKGDIEALKNALDGARLERQHKEEYEGLRRLCVRYPRRETTEAANATLRGSIRELEEASESNIKVLKLRKKQFTTLLHVVNELTEELEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM90</accession>
    <name>C1MM90_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_14939</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057359.1">
        <property type="nucleotide sequence ID" value="XM_003057313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM90"/>
    <dbReference type="STRING" id="564608.C1MM90"/>
    <dbReference type="GeneID" id="9682798"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14939"/>
    <dbReference type="eggNOG" id="KOG4033">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NLCCETI"/>
    <dbReference type="OrthoDB" id="2157380at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019332">
        <property type="entry name" value="OSCP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21439">
        <property type="entry name" value="OXIDORED-NITRO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21439:SF0">
        <property type="entry name" value="PROTEIN OSCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10188">
        <property type="entry name" value="Oscp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="192" mass="21910" checksum="239C998DFD4F9B37" modified="2009-05-26" version="1" fragment="single">MAPSMHALPLVICNMGCEMMYILEQRLRAQSIKPDKAVKVLDDVSRAMFDASFVDELFRPQEMYTESSLKHVFTKLAHASIMRLSESSMGKLFDLMTMGFKYQLTQCLTPTQIVDVTLTHVVTVRSYLTDESVIALLDAFEAKCRDVYGRFTVNEWIDLRADLHDYLKDYRVKVSLFLQAGVQKSDGSFCVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MME5</accession>
    <name>C1MME5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_46784</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057391.1">
        <property type="nucleotide sequence ID" value="XM_003057345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MME5"/>
    <dbReference type="GeneID" id="9682354"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46784"/>
    <dbReference type="eggNOG" id="KOG2508">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANVNVWM"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF100">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="180"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="169"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="513" mass="55375" checksum="4C35F7D2CB7FFF10" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMI4</accession>
    <name>C1MMI4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_32486</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057412.1">
        <property type="nucleotide sequence ID" value="XM_003057366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMI4"/>
    <dbReference type="GeneID" id="9682372"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32486"/>
    <dbReference type="eggNOG" id="KOG2234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LVFACEC"/>
    <dbReference type="OrthoDB" id="408493at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="386" mass="40496" checksum="90500699EB5170EC" modified="2009-05-26" version="1">MFVKAQGPKFRKARKLLKWEDGTFLDAIAFMATELSVSFDEVAMKVARYGPAPSELAAEGGVVKGFSSVNPQVGVFFCVLLALQYAAQPFLIKSFIPENVNKVSLVFACECVKIVIALVIMIGEGSLKANFKNWTPKVGLLSVVPAVVYAGQNFLLQTAYGSMDSVTFNCLNQTKLVSTALCVYLFFGVRQSFTQVVALGGLLLAGVMLSMDETGVETGVGVAAVLTASATSGVASAATQYSLQAHRRSSNAMTIEMALAAIPFLISSAGITSVADFDVLFANWTRATWVPVITSAFGGIFVGQVTKHLGGVAKGFAIVGGLVLTGIVQSAAVGALEVQHLVGLVLVAWSTYAHAANPPKPIDRVPPPRPGGAVSPVSSPQKMKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN15</accession>
    <name>C1MN15_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56742</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057024.1">
        <property type="nucleotide sequence ID" value="XM_003056978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN15"/>
    <dbReference type="GeneID" id="9682463"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56742"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="252" mass="27984" checksum="B3140062A633E09F" modified="2009-05-26" version="1">MTPRGEKIMRARNPSSARDTYRERPEAFRREQDDGMPSWTPRSWGGGSQRSQRSGGGDGGGGPEGGRGGWEAFKARFWRSNGGDAAPRAPPPRPRDAREERYRAERNQRVGRLRRALSDNGGSSGRAASSLSSSRPPPPAFEFEFDDIEEGFERDDGVEMRETAAAAARTRARHERMGAPARARGEPRPAAAAAVPPSSRRARAEAARAPPLRHPLEQWSLRQQHELKKRGYADEDFSPYRYTPEGRGHAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN69</accession>
    <name>C1MN69_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Small nuclear ribonucleoprotein G</fullName>
            <shortName evidence="10">snRNP-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_56803</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in pre-mRNA splicing.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Probable common Sm protein, is found in U1 and U2 snRNPs and may be part of the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057528.1">
        <property type="nucleotide sequence ID" value="XM_003057482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN69"/>
    <dbReference type="STRING" id="564608.C1MN69"/>
    <dbReference type="GeneID" id="9682967"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56803"/>
    <dbReference type="eggNOG" id="KOG1780">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IMWECID"/>
    <dbReference type="OrthoDB" id="2146at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043186">
        <property type="term" value="C:P granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034719">
        <property type="term" value="C:SMN-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01719">
        <property type="entry name" value="Sm_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000023">
        <property type="entry name" value="Small nuclear ribonucleoprotein G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034098">
        <property type="entry name" value="Sm_G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF2">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00059471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH59173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="71" mass="7792" checksum="847FDDD5F30EFBAC" modified="2009-05-26" version="1">MDKKLRLKLNGNRGVLGVLRGFDQFLNLVLDECVDDSTSDKEPLGMVVVRGNSISALEALEHIPAAVRKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNS2</accession>
    <name>C1MNS2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56008</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057159.1">
        <property type="nucleotide sequence ID" value="XM_003057113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNS2"/>
    <dbReference type="STRING" id="564608.C1MNS2"/>
    <dbReference type="GeneID" id="9682134"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56008"/>
    <dbReference type="OMA" id="LDWIAFP"/>
    <dbReference type="OrthoDB" id="1432093at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051181">
        <property type="entry name" value="CAF1_poly(A)_ribonucleases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092">
        <property type="entry name" value="POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092:SF22">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="476"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="476"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="513" mass="52696" checksum="4F24DD591EA0D293" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNT4</accession>
    <name>C1MNT4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_3527</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tubulin polyglutamylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056701.1">
        <property type="nucleotide sequence ID" value="XM_003056655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNT4"/>
    <dbReference type="STRING" id="564608.C1MNT4"/>
    <dbReference type="GeneID" id="9682605"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3527"/>
    <dbReference type="eggNOG" id="KOG2157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DWNFYWS"/>
    <dbReference type="OrthoDB" id="564098at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF31">
        <property type="entry name" value="POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="407" mass="45546" checksum="A1F388DB1C939AD5" modified="2009-05-26" version="1" fragment="single">LKWRSDFDKFVVVSNFEKRGWERWRDPGPDAADAGAADAHQTSSSWNVYWANVHAAKHLFHPSAESRLGDHQVVNHFPNHYELTRKDLMVKNVKRYRKELEKEAALAAALRGNGLGGVAVPTPTDHLDFVPLTFSLPADYSLFAEEFRRGGGDNARATNATTWIMKPTGKAQGKGIFLVNKLAQVKRWANTGGALAANNSAAHSTSNKHQSDRDKTEPPAQEAYIVSRYVHNPLLIGGKKFDLRLYVTVTSYRPLRAFISKLGFARFCNVKYSGDVADIDNPFVHLTNVAIQKRGEEYNESHGNKWPLRDLRLHLESTRGKTATDALFAAMRDCVTHSLRAVSNVMVNDRHCFELYGYDLLVDESLKPWLIEVNASPSLSATTEADRRLKCRVIRDALLVAVPPGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP29</accession>
    <name>C1MP29_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GPI inositol-deacylase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56125</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056747.1">
        <property type="nucleotide sequence ID" value="XM_003056701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP29"/>
    <dbReference type="GeneID" id="9682654"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56125"/>
    <dbReference type="eggNOG" id="ENOG502QRTI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2016516at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31934">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31934:SF5">
        <property type="entry name" value="OS05G0557900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GPI inositol-deacylase PGAP1-like alpha/beta" evidence="3">
        <location>
            <begin position="225"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="531" mass="56275" checksum="C37E2C69A749352C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP52</accession>
    <name>C1MP52_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_56149</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CONSTANS family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056761.1">
        <property type="nucleotide sequence ID" value="XM_003056715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP52"/>
    <dbReference type="STRING" id="564608.C1MP52"/>
    <dbReference type="GeneID" id="9682663"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56149"/>
    <dbReference type="eggNOG" id="KOG1601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AFLCVNC"/>
    <dbReference type="OrthoDB" id="153872at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19821">
        <property type="entry name" value="Bbox1_BBX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010402">
        <property type="entry name" value="CCT_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045281">
        <property type="entry name" value="CONSTANS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049808">
        <property type="entry name" value="CONSTANS-like_Bbox1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31319">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31319:SF77">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06203">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51017">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="9">
        <location>
            <begin position="2"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="CCT" evidence="10">
        <location>
            <begin position="261"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="190"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="329"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="381"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH58406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="424" mass="44884" checksum="31FA63B088BACFB1" modified="2009-05-26" version="1">MTNKMPCDNCHAAPAEWFCAHDGANLCARCDVAIHTANKLAMRHERIPMEQKLANDALCQSINPTNDGFDTEMGVARNEQASTSSGAPTNETSNDLDWLVSGPHGNMDDPLSNLLDMHQDAHDSSNGDASHFGLDDASLWGSHGGFGNGNHLSSAAFRNSDARRELSAQPVVGDSAGFVTGNGAAMMGQGHADGMQRQQNDGKEISSTSGTSETTQAPTQMMPPHAGGQVNFSHGGGAPGGPGSPHYDQVLTRPFATSALRHAQLQRYRAKRLARHLGHKKIRYECRKTLADNRPRIKGRFAKVHSDPNLAAAALAAVQSCPDLTALNVVGEDKESSEDSNSKKGGRNAKSRLSNGSGSNESSSPKLKNPAHKASSKKPNTRGSGASSPEQWDSTAGVSLRSGGKGMPYTQSEVSLVDLGRRLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPE3</accession>
    <name>C1MPE3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_15302</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057268.1">
        <property type="nucleotide sequence ID" value="XM_003057222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPE3"/>
    <dbReference type="STRING" id="564608.C1MPE3"/>
    <dbReference type="GeneID" id="9682247"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15302"/>
    <dbReference type="eggNOG" id="KOG2682">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ATHSCID"/>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="8">
        <location>
            <begin position="112"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="413" mass="45196" checksum="A8EF84F65F613AE2" modified="2009-05-26" version="1">MGGSDPLPGDDPRDEAPAGITDDARRDDTTAKTDSTVEASDGSEEEHSNRGLAEVDSTDAVASVSGSDDDEEVEEELTGLAALIRKLALKAEEKNATEAAAEEEPATFDTTPLLSTFDVAGVAEYITSGKAKNVIVMVGAGISVSAGIPDFRTPGTGLYDNLQKYDLPHPTAVFELDYFRENPSPFYLLAKELYPGQYPPTPTHHFIHLLHKKGILLRCFSQNIDSLEAATGLPRELIVPAHGNFDTARCLNGHDADVDEVRQHVDDGIPMRCKDCDELVKPDIVFFGENLPERFHTLARRDFPECDLLVIAGTSLEVHPFAGLIDFPNEDVPRFLVNREKVGEMDERMREFSRLVGRGAGLNFGEDNRRDALFLGDCDAGFAELARLLGWGDELDELVRAGVEKVKSPTIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPP2</accession>
    <name>C1MPP2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_26148</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Endomembrane system</location>
            <topology evidence="9">Lipid-anchor</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057987.1">
        <property type="nucleotide sequence ID" value="XM_003057941.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPP2"/>
    <dbReference type="STRING" id="564608.C1MPP2"/>
    <dbReference type="GeneID" id="9683425"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26148"/>
    <dbReference type="eggNOG" id="KOG0394">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FAFMIET"/>
    <dbReference type="OrthoDB" id="1436450at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01862">
        <property type="entry name" value="Rab7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000295">
        <property type="entry name" value="Ras-related protein Rab7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF20">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB-7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH57938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="206" mass="22908" checksum="AB001116649B8CE4" modified="2009-05-26" version="1" fragment="single">MASRKRTLLKVIILGDSGVGKTSLMNQYVNRKFSKQYKATIGADFLTKEVQVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLTYDVNAGKTFENIDNWRDEFLIQANPADADSFPFVVLGNKVDVDEGKARVVSEKKAKSWCAGKGNIPYFETSAKEDYNVEAAFQCIARNALKNETEEEVYLPDTVDVNGRRGAQQAGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPT5</accession>
    <name>C1MPT5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57027</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057640.1">
        <property type="nucleotide sequence ID" value="XM_003057594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPT5"/>
    <dbReference type="GeneID" id="9683109"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57027"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="91" mass="10028" checksum="6B2D46AA37966CE3" modified="2009-05-26" version="1">MAPLFTSAREGDEGYERSAGVARRMGMATEEGEGRGARRRRRRRRRREEKIALIDREAGKKVVVGVGAASSVLALESVFVALRRALEDGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPY0</accession>
    <name>C1MPY0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_57084</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057665.1">
        <property type="nucleotide sequence ID" value="XM_003057619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPY0"/>
    <dbReference type="STRING" id="564608.C1MPY0"/>
    <dbReference type="GeneID" id="9683465"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57084"/>
    <dbReference type="eggNOG" id="KOG2186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QQHTSCV"/>
    <dbReference type="OrthoDB" id="21474at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.490:FF:000001">
        <property type="entry name" value="cell growth-regulating nucleolar protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039999">
        <property type="entry name" value="LYAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014898">
        <property type="entry name" value="Znf_C2H2_LYAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13100:SF10">
        <property type="entry name" value="CELL GROWTH-REGULATING NUCLEOLAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13100">
        <property type="entry name" value="CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08790">
        <property type="entry name" value="zf-LYAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51804">
        <property type="entry name" value="ZF_C2HC_LYAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger C2H2 LYAR-type" evidence="9">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="124"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH57616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="228" mass="24345" checksum="6BAAACA7DC29A331" modified="2009-05-26" version="1">MPWFQCEDCGDTLKKPKVKGHASGCSASRFSCVDCLQVFDRWSVQQHTSCVTEHEKYALSITKPGQEHLMHASAAASGGGGGGGAGGGGNGGGVVGESFLATKPPWDCACCRVKCTSQETLLGHAAGKRHRSKARGALAKQGLGLDGKPLPVEGGDDGAGKGGGGGGGEAEEEEKEAPVEEKREKKEKREKKEKKEKKEKKEKKEKKEKRDRGGDAEEKKEKKRKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ07</accession>
    <name>C1MQ07_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">glutamate synthase (NADH)</fullName>
            <ecNumber evidence="18">1.4.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">GLT</name>
        <name evidence="24" type="ORF">MICPUCDRAFT_57115</name>
    </gene>
    <organism evidence="25">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="21">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="21">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.14" evidence="18"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057676.1">
        <property type="nucleotide sequence ID" value="XM_003057630.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MQ07"/>
    <dbReference type="GeneID" id="9683481"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57115"/>
    <dbReference type="eggNOG" id="KOG0399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WDGPAAM"/>
    <dbReference type="OrthoDB" id="4327079at2759"/>
    <dbReference type="UniPathway" id="UPA00045"/>
    <dbReference type="UniPathway" id="UPA00634">
        <property type="reaction ID" value="UER00690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097054">
        <property type="term" value="P:L-glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000031">
        <property type="entry name" value="Glutamate synthase 1 [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000009">
        <property type="entry name" value="Glutamate synthase 1 [NADH] chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000043">
        <property type="entry name" value="Glutamate synthase 1 [NADH] chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000113">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000022">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.60:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000314">
        <property type="entry name" value="Uncharacterized protein, isoform E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="entry name" value="Glutamate synthase, alpha subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012220">
        <property type="entry name" value="Glu_synth_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008730">
        <property type="entry name" value="PRK11750.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000187">
        <property type="entry name" value="GOGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="Alpha subunit of glutamate synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17 21" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0288">FMN</keyword>
    <keyword evidence="16" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="15 21" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="23">
        <location>
            <begin position="94"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="898"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1024"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="915"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="20">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="1248"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="1254"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="1259"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00024383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EEH57627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2181" mass="233990" checksum="6B98106DD964449F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQR3</accession>
    <name>C1MQR3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_16484</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057804.1">
        <property type="nucleotide sequence ID" value="XM_003057758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQR3"/>
    <dbReference type="STRING" id="564608.C1MQR3"/>
    <dbReference type="GeneID" id="9683609"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16484"/>
    <dbReference type="eggNOG" id="ENOG502RXTW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PEHETRC"/>
    <dbReference type="OrthoDB" id="409625at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044673">
        <property type="entry name" value="DCL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33415">
        <property type="entry name" value="PROTEIN EMBRYO DEFECTIVE 514"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33415:SF12">
        <property type="entry name" value="PROTEIN EMBRYO DEFECTIVE 514"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11523">
        <property type="entry name" value="DUF3223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="156" mass="16241" checksum="A2CA4F00CC7D92F8" modified="2009-05-26" version="1">MVKYFSWILNNMTINQDMNDYERMVVEPCLRTAHPDAEKKIGSGIKAFQIRTHPEHETRCYTVIRTDGTTEDFSYRKCVEVLFPGYTPNAPKNSGGRGGGRGGGGRGRGGGGRGRGGGGRGGGGRGGGGRGGRGGGRGGRGGGRGGRGGRGRGGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQV4</accession>
    <name>C1MQV4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">5-amino-6-(5-phosphoribosylamino)uracil reductase</fullName>
            <ecNumber evidence="2">1.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_15833</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.193" evidence="2"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058195.1">
        <property type="nucleotide sequence ID" value="XM_003058149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQV4"/>
    <dbReference type="STRING" id="564608.C1MQV4"/>
    <dbReference type="GeneID" id="9683259"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15833"/>
    <dbReference type="eggNOG" id="KOG1018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GIRHPLK"/>
    <dbReference type="OrthoDB" id="206452at2759"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00402"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004794">
        <property type="entry name" value="Eubact_RibD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011549">
        <property type="entry name" value="RibD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050765">
        <property type="entry name" value="Riboflavin_Biosynth_HTPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00326">
        <property type="entry name" value="eubact_ribD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00227">
        <property type="entry name" value="ribD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02464">
        <property type="entry name" value="ribofla_fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011:SF7">
        <property type="entry name" value="2,5-DIAMINO-6-RIBOSYLAMINO-4(3H)-PYRIMIDINONE 5'-PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_8G06820)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial bifunctional deaminase-reductase C-terminal" evidence="6">
        <location>
            <begin position="217"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="NADAR" evidence="7">
        <location>
            <begin position="465"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="628" mass="66628" checksum="0E11168C98A6246D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR27</accession>
    <name>C1MR27_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_15978</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058232.1">
        <property type="nucleotide sequence ID" value="XM_003058186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR27"/>
    <dbReference type="STRING" id="564608.C1MR27"/>
    <dbReference type="GeneID" id="9683295"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15978"/>
    <dbReference type="eggNOG" id="KOG0060">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KQFHDME"/>
    <dbReference type="OrthoDB" id="422637at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF55">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="76"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="396"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="636"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="636"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="652"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="663" mass="71828" checksum="6EDD61FFBAF1E60E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-11-30" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR42</accession>
    <name>SYAP_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alanine--tRNA ligase, chloroplastic/mitochondrial</fullName>
            <ecNumber evidence="1">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="1">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ORF">MICPUCDRAFT_16345</name>
    </gene>
    <organism>
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="1"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057866.1">
        <property type="nucleotide sequence ID" value="XM_003057820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR42"/>
    <dbReference type="SMR" id="C1MR42"/>
    <dbReference type="STRING" id="564608.C1MR42"/>
    <dbReference type="GeneID" id="9683676"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16345"/>
    <dbReference type="eggNOG" id="KOG0188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GFDMEME"/>
    <dbReference type="OrthoDB" id="2423964at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00673">
        <property type="entry name" value="AlaRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.40:FF:000001">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.54.20:FF:000001">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.54.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03134">
        <property type="entry name" value="Ala_tRNA_synth_plantC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027522">
        <property type="entry name" value="Ala_tRNA_synth_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0150">Chloroplast</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0934">Plastid</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0809">Transit peptide</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="transit peptide" description="Chloroplast and mitochondrion">
        <location>
            <begin position="1"/>
            <end status="unknown"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000402304" description="Alanine--tRNA ligase, chloroplastic/mitochondrial">
        <location>
            <begin status="unknown"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="581"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="585"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="683"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="687"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03134"/>
        </source>
    </evidence>
    <sequence length="899" mass="95154" checksum="50631B1782D30122" modified="2009-05-26" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRH4</accession>
    <name>C1MRH4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Vacuolar ATPase assembly protein VMA22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57653</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057927.1">
        <property type="nucleotide sequence ID" value="XM_003057881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRH4"/>
    <dbReference type="GeneID" id="9683365"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57653"/>
    <dbReference type="OMA" id="HNAGAMS"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040357">
        <property type="entry name" value="Vma22/CCDC115"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31996">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31996:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00093634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="256" mass="26447" checksum="5B1CA0266A6E96D2" modified="2009-05-26" version="1">MAFLGEINHNAGAMSPRERTEAELLEILELSEELVALKLSLASSMSDANMDVASARIASPFGHHAVGPLAFPTDMEALVGVRVTRREADGDDAGGDDAAAKQASAATREYEVVDRPPRNDEGVAGDDEVKKRKDAAAAGPDGGGLRRRATAAAGAAAGIGAAVAAAAATPPPDALARDGPDPDPDPDPDPRRRRTRPRRPPASWFNGGVPHVGLTRAAGAYAACVETVARAATVSSKIDAALCRFERRGRDSTEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRP3</accession>
    <name>C1MRP3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58177</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058543.1">
        <property type="nucleotide sequence ID" value="XM_003058497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRP3"/>
    <dbReference type="GeneID" id="9684349"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58177"/>
    <dbReference type="OMA" id="NRQAQIF"/>
    <dbReference type="OrthoDB" id="10501774at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="335" mass="36236" checksum="8A40682B0EBC902B" modified="2009-05-26" version="1">MGGIGGKGKGARRREKLKDNAKSFDKKTGTFREPKLELVDGKVSKQDMLKAPSSFRRFMEATRRAKEQAARRERQYNKSQGLDVSDDEVDDPLVNAPDVGTGAKAKSKNDAENESDKDTGDDDALTWLRPDVGGEEEPDELDAAAELRKKRKKRAGDEDGANVKKKYQSLRERKSAARKAMKAMKDEDESFIFGKTSEARVEKSRGGDVSFGEVADAPPTITLKRKSGGKGAKPVPVAESGHKIAGSKGAGNRQAQIFQSLMRKSAKDGGGQKAPPGVGLRRVAEMTALREQVISGYRQMKGRPSNNGRSASLATDPSRLFSAVGGATIRRDAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRQ5</accession>
    <name>C1MRQ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_17294</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FtsZ family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058549.1">
        <property type="nucleotide sequence ID" value="XM_003058503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRQ5"/>
    <dbReference type="STRING" id="564608.C1MRQ5"/>
    <dbReference type="GeneID" id="9683988"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17294"/>
    <dbReference type="eggNOG" id="ENOG502QRFN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IMNQGGV"/>
    <dbReference type="OrthoDB" id="70257at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010020">
        <property type="term" value="P:chloroplast fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000023">
        <property type="entry name" value="Cell division protein FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="CELL DIVISION PROTEIN FTSZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314:SF23">
        <property type="entry name" value="PLASTID DIVISION PROTEIN FTSZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="10">
        <location>
            <begin position="10"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="11">
        <location>
            <begin position="204"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="313"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="350"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="367" mass="37955" checksum="247205A899635223" modified="2009-05-26" version="1">MPVVQANSATIKVIGCGGGGGNAVNRMIKSGIQGVEFWSLNTDAQALVQSEADNRIQIGRDTTRGLGTGGNPELGRAAAEESINEITEAVAGADLVFITAGMGGGTGSGSAPVVARIAKDAGTLTVGVVTQPFSFEGRRRQEQAKAYIEQMRANVDTLIVIPNDRLLDAVKTNTPLQQAFLLADDVLRQGVQGISDIITISGLVNVDFADVSTVMRDSGTAMLGVGQAQGTDRAVEAAMAAISMPLIEHSIDLCSGIVFNITGGKDLSLQEVSAVSDVVTSMAAPDANIIFGAVVDENFTDGIAVTIIATGFDLPEENQPPPRGQRRGDGGQFPPPPPQNVGAALPWNQRGGGASPPRGGGSWLNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRY6</accession>
    <name>C1MRY6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58278</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058957.1">
        <property type="nucleotide sequence ID" value="XM_003058911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRY6"/>
    <dbReference type="GeneID" id="9684396"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58278"/>
    <dbReference type="OrthoDB" id="44061at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="270" mass="30100" checksum="29FFDAE1AEA47D87" modified="2009-05-26" version="1">MAPPTMRRPRAREGEVSPAGKLLLVFVVAATIVYVAFGGGGSREPIDRATATAAAAATARGEARLADASLAKNLGTRETQLELRWGVDRDIATRICAKNRAFAEPSGYWVSGTTFLDDEATTFQHAVTFHDSATGLPLFVAPRVRRVRSILASFGFRKNFGFPRRPRCPLFPPPRPVPVRPRRRDLHPHPHPHPHPRDRPQGRTWREFEAESRAHGWPSFRDEEVVWENVRVLGRENNAEVISADGVTHLVRSGSHWSPYDRVGVVNAYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS16</accession>
    <name>C1MS16_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_58309</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058606.1">
        <property type="nucleotide sequence ID" value="XM_003058560.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9684409"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58309"/>
    <dbReference type="eggNOG" id="ENOG502S5DJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DWAFEAE"/>
    <dbReference type="OrthoDB" id="415691at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43042:SF3">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE YWBD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43042">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1311"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="911"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="299"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="492"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="749"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="867"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1022"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1334"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="507"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="749"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="778"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="890"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1032"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1338"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1362"/>
            <end position="1379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1379" mass="147579" checksum="F6F4BFF73DDA2CA4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS83</accession>
    <name>C1MS83_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SNF2 super family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RAD54</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_58384</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059004.1">
        <property type="nucleotide sequence ID" value="XM_003058958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS83"/>
    <dbReference type="STRING" id="564608.C1MS83"/>
    <dbReference type="GeneID" id="9684078"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58384"/>
    <dbReference type="eggNOG" id="KOG0390">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TWGHHHR"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18004">
        <property type="entry name" value="DEXHc_RAD54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000021">
        <property type="entry name" value="DNA repair and recombination protein RAD54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000332">
        <property type="entry name" value="DNA repair and recombination protein RAD54-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="194"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="539"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="734"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="865"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="748"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="867"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="888"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="909"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="926"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="980"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1018"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1031"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1087"/>
            <end position="1098"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1131" mass="121823" checksum="B936E57856E61B20" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSI4</accession>
    <name>C1MSI4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_39578</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058687.1">
        <property type="nucleotide sequence ID" value="XM_003058641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSI4"/>
    <dbReference type="GeneID" id="9684126"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39578"/>
    <dbReference type="OMA" id="LGCINVF"/>
    <dbReference type="OrthoDB" id="10683954at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="382"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="432"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="511"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="657"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="311"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="387"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="436"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="476"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="546"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="582"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="597"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="617"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="657"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="708" mass="71780" checksum="641F3A2A870B2B18" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSK4</accession>
    <name>C1MSK4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MICPUCDRAFT_45490</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 2 phosphate + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the C-terminal section; belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058695.1">
        <property type="nucleotide sequence ID" value="XM_003058649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSK4"/>
    <dbReference type="STRING" id="564608.C1MSK4"/>
    <dbReference type="GeneID" id="9683844"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45490"/>
    <dbReference type="eggNOG" id="KOG1284">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GGVHMAM"/>
    <dbReference type="OrthoDB" id="60371at2759"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10990:FF:000001">
        <property type="entry name" value="Riboflavin biosynthesis protein RibBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.870.10:FF:000001">
        <property type="entry name" value="Riboflavin biosynthesis protein RibBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00179">
        <property type="entry name" value="RibA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01283">
        <property type="entry name" value="RibBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016299">
        <property type="entry name" value="Riboflavin_synth_RibBA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001591">
        <property type="entry name" value="PRK00393.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006803">
        <property type="entry name" value="PRK09311.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00505">
        <property type="entry name" value="ribA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327:SF18">
        <property type="entry name" value="3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327">
        <property type="entry name" value="GTP CYCLOHYDROLASE II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001259">
        <property type="entry name" value="RibA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="19">
        <location>
            <begin position="222"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEH57150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="445" mass="47944" checksum="3C8DEF669185939A" modified="2009-05-26" version="1">MPAHIDGDVPTPGFATIASALEDVAAGKFVVVLDDEDRENEGDLIGAADAMTAESIAFMIKHTSGLLCVAVDDETADRLNLPLMVTSKENEDAMKTAFTVSCDLAASTTGISAGERAATIAKLGDAKAHKDEFVRPGHVFPLRYREGGVLKRTGHTEAAYDLAKLSGRGAAGVLCEITNDDAEGTMARLPQLREFSKKHDLKMILISDLVRYRRKREVLVRRTASARVPTEHGAFTAVSYKSETDGIEHVAFVYGNLDDEGKENGGSLADGDNVLVRVHSECLTGDIFGSSRCDCGNQLDMAMQRVASEGKGVIVYLRGQEGRGIGLGHKLRAYNLQDEGRDTVQANEDLGLPVDSREYGVGAAILRDLGVKTIRLMTNNPAKYHGLKGFGLTIVGRSPLFAPITLENKRYIETKRAKMGHMFGDESGAFEEAVEAAEEVNVEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSU2</accession>
    <name>C1MSU2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_17192</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058383.1">
        <property type="nucleotide sequence ID" value="XM_003058337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSU2"/>
    <dbReference type="STRING" id="564608.C1MSU2"/>
    <dbReference type="GeneID" id="9684178"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17192"/>
    <dbReference type="eggNOG" id="KOG4563">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CKSIKAN"/>
    <dbReference type="OrthoDB" id="5587616at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034080">
        <property type="term" value="P:CENP-A containing chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051730">
        <property type="entry name" value="NASP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081:SF1">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="68" mass="7535" checksum="2E86A4CBA8F40E38" modified="2009-05-26" version="1" fragment="single">MTTPTEADATTAFDEGCKSIKANDMELAIEKLARALEIRSALYGEQDIKTASAYYKYGCALFYKAQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUF0</accession>
    <name>C1MUF0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_40194</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059184.1">
        <property type="nucleotide sequence ID" value="XM_003059138.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9684925"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40194"/>
    <dbReference type="OMA" id="RKWPTGK"/>
    <dbReference type="OrthoDB" id="10693219at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025486">
        <property type="entry name" value="DUF4378"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14309">
        <property type="entry name" value="DUF4378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4378" evidence="2">
        <location>
            <begin position="1719"/>
            <end position="1839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="839"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="894"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1284"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1406"/>
            <end position="1624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="421"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="607"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="681"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="849"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="894"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="918"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="940"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1284"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1319"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1410"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1421"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1439"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1457"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1502"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1596"/>
            <end position="1621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1846" mass="195242" checksum="5BE1EED985328268" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUI1</accession>
    <name>C1MUI1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino Acid/Auxin permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_58815</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059202.1">
        <property type="nucleotide sequence ID" value="XM_003059156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUI1"/>
    <dbReference type="STRING" id="564608.C1MUI1"/>
    <dbReference type="GeneID" id="9684938"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58815"/>
    <dbReference type="eggNOG" id="KOG1305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GERWFIT"/>
    <dbReference type="OrthoDB" id="28208at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="544"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="78"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="321"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="416"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="569" mass="58572" checksum="3122A7F77F988532" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUW4</accession>
    <name>C1MUW4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_58956</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059262.1">
        <property type="nucleotide sequence ID" value="XM_003059216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUW4"/>
    <dbReference type="STRING" id="564608.C1MUW4"/>
    <dbReference type="GeneID" id="9685011"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58956"/>
    <dbReference type="eggNOG" id="KOG1375">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KRAHLHH"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02190">
        <property type="entry name" value="epsilon_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000017">
        <property type="entry name" value="Tubulin epsilon chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004057">
        <property type="entry name" value="Epsilon_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01519">
        <property type="entry name" value="EPSLNTUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="6">
        <location>
            <begin position="55"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="7">
        <location>
            <begin position="288"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="485" mass="52515" checksum="D657E47DA44C4684" modified="2009-05-26" version="1">MPREIITVQVGQCGNQIGCRFWEMALNEHAAYNAKARYDEALSSFFQNVDARRDPPVNVPVGDPIRALKARAVVVDMEEGVTNELLTGPMRDVFDSKQFITGQSGSGNNWACGSHHYGPMYRESLLEQVRRPVEEADSLQSFMLLHSLGGGTGSGLGSYLLAALADEYPDVYRFSVSVFPSDDDDVVTSPYNAMLSCAALAEHADCVLPVENQALMDIVQSIEAKSKNASPFGGRSGGVLSGSSLSGVDGGDVAGRAGHGGKPWDGMNGIAANLLLNLTAGMRFDGALNVDINEITMNLVPFPRLHFLLSSMSPVVTPADRGMTVPAPRTLDQIFSEVFSTDRQLASVDPRRNTYMACALLMRGAVNISDANRNVERLKRGLKMAHWVSDGFKVGLCDRAPVNSLYSATCLANNCAMQKPLSAICERFHKLRRKKVFLHHYTEYMDVEDIDGAAASIGSLAEEYARVDASRAPDAVPSIAPLGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUY3</accession>
    <name>C1MUY3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="4">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_27367</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="4"/>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059272.1">
        <property type="nucleotide sequence ID" value="XM_003059226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUY3"/>
    <dbReference type="STRING" id="564608.C1MUY3"/>
    <dbReference type="GeneID" id="9685020"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27367"/>
    <dbReference type="eggNOG" id="KOG1557">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RAYRQML"/>
    <dbReference type="OrthoDB" id="36455at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000741">
        <property type="entry name" value="FBA_I"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033379">
        <property type="entry name" value="FrucBisAld_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11627">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00274">
        <property type="entry name" value="Glycolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="339" mass="36657" checksum="6A72329A6439DF8B" modified="2009-05-26" version="1">MIGTPGKGITACDEGPGTIGDRLAAVGVENTEENRRSYRQVLFEARDANEYLSAAILDPETLYQKSSDSGDLFPKVLMDRGIVPGVKPHLKVYALPGQSGATVMQGLDSLAARCAEYKAAGCEFAKWRSPMEIDVANGQPSDVIIEANMRDLARYALICQAEGLVPIVEPDVSLKGDHDLETAVRVNLKIQSELFKAMLDHGVYMEGAVLKSNMVNPGKDCATSYTVDEIAVANLQVFRRCFPTAMVTANFLSGGQSLEDAAARLDAINKHKGPRDPWNLSFSWSAAIQMPLFQLCKGTGELQLEAMGELYVKELAIASAAARGEWTRSGTDGDHKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVJ0</accession>
    <name>C1MVJ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_37513</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059760.1">
        <property type="nucleotide sequence ID" value="XM_003059714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVJ0"/>
    <dbReference type="STRING" id="564608.C1MVJ0"/>
    <dbReference type="GeneID" id="9685485"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37513"/>
    <dbReference type="eggNOG" id="ENOG502QUU3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AECGYKE"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF19">
        <property type="entry name" value="CATALYTIC_ HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="3">
        <location>
            <begin position="22"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="313" mass="33834" checksum="AB4EF3AA615BEEC6" modified="2009-05-26" version="1">MASKATTPPNDAPSPSPPLVLDAHLHVWPTPTSYAYVEGKEPPASLATTATAEALVSAMDDAGIHGALIVQPINLLHDHAYVADVVRRYPGRFVACALADPTRGIAGVNDLSRLLHAGDAPGNASTGTYRAVRFNPGLWPEGARMTDEVGVAMFELCGERRAPVGFMCFHGLHLHVEDIKELMRASPRTPVMIDHFGFCKGVDDPNWKALLELAKFPQVGVKASAQFRVLPLDASDEDKEWPYPTTGAQLRQLIDAFGVERVLWGSDFPYVTRECGYAEAATILENCGAGVTPEEKALLMGGNLQRTFPGGWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVM8</accession>
    <name>C1MVM8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_27574</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060065.1">
        <property type="nucleotide sequence ID" value="XM_003060019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVM8"/>
    <dbReference type="STRING" id="564608.C1MVM8"/>
    <dbReference type="GeneID" id="9685219"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27574"/>
    <dbReference type="eggNOG" id="KOG0861">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MINEIYM"/>
    <dbReference type="OrthoDB" id="27923at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15867">
        <property type="entry name" value="R-SNARE_YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045848">
        <property type="entry name" value="R-SNARE_YKT6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806:SF1">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Longin" evidence="9">
        <location>
            <begin position="7"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="139"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="199" mass="22407" checksum="A3B78684D4526419" modified="2009-05-26" version="1">MKVTALSLWKWNGDKAEPTCLGKAEDVAEFGYFQRGSVREMLTFISRTIVKRTQPGQRQSVEQDQYLVHVTNRGGLVAIAVMDREYPSRSAFCVLSKMSDDYVARVGDAWKTVASDDARGDAILAEAIAKYQDPMEADKILKIQRELDETKVVLHKTIDSVLARGEKLDNLVDKSTDLSLASQMFYKQAKKQNQCCTMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVQ1</accession>
    <name>C1MVQ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_18738</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060079.1">
        <property type="nucleotide sequence ID" value="XM_003060033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVQ1"/>
    <dbReference type="GeneID" id="9685517"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18738"/>
    <dbReference type="OrthoDB" id="497158at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051938">
        <property type="entry name" value="Apopto_cytoskel_mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44145">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44145:SF3">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="14"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="62" mass="6732" checksum="6DB155E585F05B61" modified="2009-05-26" version="1" fragment="single">MASSSASSPRTREDACATLGIPVYATRADAKKSYRALARAFHPDKGGDAERFQAVQRAYELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW74</accession>
    <name>C1MW74_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_47764</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059873.1">
        <property type="nucleotide sequence ID" value="XM_003059827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW74"/>
    <dbReference type="STRING" id="564608.C1MW74"/>
    <dbReference type="GeneID" id="9685606"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47764"/>
    <dbReference type="OMA" id="NCASELH"/>
    <dbReference type="OrthoDB" id="568331at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051966">
        <property type="entry name" value="RPAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423:SF4">
        <property type="entry name" value="OUTER ENVELOPE PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="260" mass="28642" checksum="0814478F45118489" modified="2009-05-26" version="1" fragment="single">MAMKRNRVRLTDDERRKFDDVGLDDINAMTDPATLHKLMQYMEEEGFPQTASVVKNRLIALGAKKPDAVVDSETEADAASFAEDLVRWTNDLKAADVADAAEPTFVRARDRDGDGVAPIRCIPTTTVNPTGADEAAKKRAKDDAEKSDDGEGRPVPEELSEAESMLFGASGLTPDDSEDMSVANTAVDVKRTLRAMEGATARERRWVATREKEKGNELFKAREYRSAIEAYGLSLALDPSSAATRCNRAAAYMKLKRWHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWH8</accession>
    <name>C1MWH8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59773</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060217.1">
        <property type="nucleotide sequence ID" value="XM_003060171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWH8"/>
    <dbReference type="GeneID" id="9685655"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59773"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="190" mass="21434" checksum="0D059561366F184D" modified="2009-05-26" version="1">MDEEDLPLLNEEPARRRRRRRKTQTCCGCFAWDTCKWILWIAAGAAGAWIVYHLYLHYFGGTSDSHAEFTRVKAMRYATFASATYAPLNEVKAWDCKECVKSDVVPRNITVVETTPLFDGRVDVFTITPLGEPSKLVVAFRGETTESAAAWMGIEHAFAEATFGPQYANVKVRSIHWSPYDPVRVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWJ5</accession>
    <name>C1MWJ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_34421</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059933.1">
        <property type="nucleotide sequence ID" value="XM_003059887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWJ5"/>
    <dbReference type="STRING" id="564608.C1MWJ5"/>
    <dbReference type="GeneID" id="9685667"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34421"/>
    <dbReference type="eggNOG" id="KOG3418">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NQWFFTK"/>
    <dbReference type="OrthoDB" id="1908962at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.770:FF:000001">
        <property type="entry name" value="60S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="4">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="135" mass="15510" checksum="832EBD5836930AB9" modified="2009-05-26" version="1">MVKFLKANKVVVVLNGRYAGKKAVIVKNYDEGTSSRPYGHALVCGLSTYPRKVTKKQTKKQQDKHSRVKTFIKTVNYNHLMPTRYTLDVDLKTTVTPDVLDNATKKVAARKEAKKVLEERFKTGKSRWFFTRLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWN0</accession>
    <name>C1MWN0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_65243</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDK5RAP3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059656.1">
        <property type="nucleotide sequence ID" value="XM_003059610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWN0"/>
    <dbReference type="STRING" id="564608.C1MWN0"/>
    <dbReference type="GeneID" id="9685393"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65243"/>
    <dbReference type="eggNOG" id="KOG2607">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="340432at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008491">
        <property type="entry name" value="CDK5RAP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14894">
        <property type="entry name" value="CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14894:SF0">
        <property type="entry name" value="CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05600">
        <property type="entry name" value="CDK5RAP3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="598" mass="62077" checksum="DAD883D77B89B007" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX32</accession>
    <name>C1MX32_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60012</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060620.1">
        <property type="nucleotide sequence ID" value="XM_003060574.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9685766"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60012"/>
    <dbReference type="eggNOG" id="ENOG502SZNG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GTWGRPS"/>
    <dbReference type="OrthoDB" id="10689130at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="537"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="695"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="748"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="881"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1227"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1306"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="267"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="331"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="482"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="538"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="695"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="756"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="890"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="954"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="971"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1073"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1157"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1198"/>
            <end position="1207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1397" mass="149554" checksum="3C23E88CC9C252FB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX86</accession>
    <name>C1MX86_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60066</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060352.1">
        <property type="nucleotide sequence ID" value="XM_003060306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX86"/>
    <dbReference type="GeneID" id="9685790"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60066"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="311" mass="34696" checksum="A02485905488BB30" modified="2009-05-26" version="1">MGLFSPRKAKKPPPAIAEDEDPPPPPPPPPKPNAFKKSATAMKANAKLQRLNPVTYAKTAEREYRAARAALARREAELKQCEKRVANKQLAYEYQERELAWHLQSLRAELADARDHGAKKHEEDVMDLVDDADARAKQLKKLRAPGGCPAVEALTARIEELNVEIVNLTKSAEKWKDVWEERGGDVSSEEEEEEVKEEEAAEAPAPAKPRTPERAPPRAPSGEKENKREQQAASKKKKSSKMTPQKSPPKRNEAQIRAIVARMQNRDGPKKSLWRKGAYEGHKPIPTRGGVPIKPRESTKQKNESGACVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXD5</accession>
    <name>C1MXD5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="10">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PHO1</name>
        <name evidence="13" type="ORF">MICPUCDRAFT_49649</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="10"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060376.1">
        <property type="nucleotide sequence ID" value="XM_003060330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXD5"/>
    <dbReference type="STRING" id="564608.C1MXD5"/>
    <dbReference type="GeneID" id="9686112"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49649"/>
    <dbReference type="eggNOG" id="KOG2099">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GIEPCRC"/>
    <dbReference type="OrthoDB" id="9215500at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04873">
        <property type="entry name" value="ACT_UUR-ACR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04300">
        <property type="entry name" value="GT35_Glycogen_Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000002">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000003">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000197">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011833">
        <property type="entry name" value="Glycg_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035090">
        <property type="entry name" value="Pyridoxal_P_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02093">
        <property type="entry name" value="P_ylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468:SF30">
        <property type="entry name" value="ALPHA-1,4 GLUCAN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00102">
        <property type="entry name" value="PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="9 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="12">
        <location>
            <begin position="91"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1008"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1015"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH55145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1027" mass="116140" checksum="9E7C32B37BDB5197" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXL1</accession>
    <name>C1MXL1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_47925</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060417.1">
        <property type="nucleotide sequence ID" value="XM_003060371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXL1"/>
    <dbReference type="GeneID" id="9685855"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47925"/>
    <dbReference type="OMA" id="DEDAMHF"/>
    <dbReference type="OrthoDB" id="2137924at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="685"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="712"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="756"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="954" mass="99022" checksum="7592FED9DA393D96" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXU2</accession>
    <name>C1MXU2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60290</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060754.1">
        <property type="nucleotide sequence ID" value="XM_003060708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXU2"/>
    <dbReference type="STRING" id="564608.C1MXU2"/>
    <dbReference type="GeneID" id="9685892"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60290"/>
    <dbReference type="eggNOG" id="ENOG502S73D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RNSMPAN"/>
    <dbReference type="OrthoDB" id="70850at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38585">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38585:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="394" mass="41508" checksum="AA6AF2B8C5CF1755" modified="2009-05-26" version="1">MGFGRDRDEYPASSVAEAIRCARASSRRASPSPTHPIARLAETTERTHDGSRDASPPRRASRRPVPSLPPSSRRFPSAVGVLDDLATSAPGVAAAATSAAAFVLTANAARRAAYATGVSCATPILGVAWGLCATAGASVVAGQAARAALEASRSGGGGWSGSVGVADVANAARVGWSSFASSSSSARSGFFRGALGGLGGRDAAWDEGEMTLDAMLGTVLYAFIGRGVHSALPSDVSHPGAMRRNSMPANGAHYASESQKRTLARWMRRDGCHHCGTRSGAVIGDHMPPNKMAFGSSAAAEASRNGTLSLGARAWNFLRMVPRQRFFPQCRACSDLQSTAVRLRAKSLVMHNGGVRIGCVVASVVAARHYVMWKHPREYERFERRVEEFVLRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYX2</accession>
    <name>C1MYX2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_37554</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060857.1">
        <property type="nucleotide sequence ID" value="XM_003060811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYX2"/>
    <dbReference type="STRING" id="564608.C1MYX2"/>
    <dbReference type="GeneID" id="9686554"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37554"/>
    <dbReference type="eggNOG" id="KOG0901">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IRQSKPW"/>
    <dbReference type="OrthoDB" id="1882674at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.150.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_uL14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006344">
        <property type="entry name" value="PRK08571.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="141" mass="15026" checksum="724BFBC52DD3C44C" modified="2009-05-26" version="1">MSKRGSGGIASGTKYKMSIACPVGAVMNCADNTGAKNLYVIAVKRWGSRLNRIPGASTGGMVMATVKKGKPDLRKKVFPAIVVRQRKPFRRKDGLVIYFEDNAGVIVNPKGEMKGSAITGPVAKECADLWPRIASAANSIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYZ6</accession>
    <name>C1MYZ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63247</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060870.1">
        <property type="nucleotide sequence ID" value="XM_003060824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYZ6"/>
    <dbReference type="GeneID" id="9686565"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63247"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="615" mass="66775" checksum="7A34C122AD8F4971" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ86</accession>
    <name>C1MZ86_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_19725</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061171.1">
        <property type="nucleotide sequence ID" value="XM_003061125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ86"/>
    <dbReference type="STRING" id="564608.C1MZ86"/>
    <dbReference type="GeneID" id="9686354"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19725"/>
    <dbReference type="eggNOG" id="KOG0907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DWSMTTC"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="101" mass="10989" checksum="97107F76298FB993" modified="2009-05-26" version="1" fragment="single">TELRATLEEASAADALCVVDWSMTTCGPCQRVKPMYEQMARSCANALFVGIDVQASSANADLARKAAVTAFPTFHLYKKMQRVAEMRGADVPRLAQLIATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ90</accession>
    <name>C1MZ90_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48057</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060917.1">
        <property type="nucleotide sequence ID" value="XM_003060871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ90"/>
    <dbReference type="GeneID" id="9686612"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48057"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="900"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="919"/>
            <end position="929"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="949" mass="100578" checksum="0507A875AD7A4D03" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZG0</accession>
    <name>C1MZG0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_41301</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061211.1">
        <property type="nucleotide sequence ID" value="XM_003061165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZG0"/>
    <dbReference type="GeneID" id="9686650"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41301"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="443" mass="45523" checksum="C6A4847A40F1FD54" modified="2009-05-26" version="1">MDEPKRNASDETRREEAAALSLHEPRLPRRAGAARSSPLHLARGAGGLARVSPMTATIDDAERLLVSASFAEASAAASAARLAARDPADRVAAECVWIQAEFKLGALSTHDADAARMLAGTTLEPGGATFEPASLVLWCKLRLHDADDAAGEEAGEAALWTMFERAKERCAAAPSTSSPAAAASTSSPSSAPTGGGTPRAEDETSTGTIEDDIVMGTAAWMYAVHLLCERRKRPDAAAKWLQYAWGFLPPDARERLTDSIVSYCRAGGDGDGGGSGSGGGEAAATTAGIEPAATAGERMPTPSPAPGSARRARSKPGRGRSAAHPRGTPGEEEGAGEIEIEAAGGVLEGDANANRPGTPPAGTPPPPPPRSDRPSTLSELLAAVAESVDGLSFSKMTDATSPTFVRDAAVGGVAAVLAGVAAYAVFAEARGSWRRWRARRGRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZL2</accession>
    <name>C1MZL2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_19557</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PRP39 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061239.1">
        <property type="nucleotide sequence ID" value="XM_003061193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZL2"/>
    <dbReference type="STRING" id="564608.C1MZL2"/>
    <dbReference type="GeneID" id="9686678"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19557"/>
    <dbReference type="eggNOG" id="KOG1258">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HANFERR"/>
    <dbReference type="OrthoDB" id="10265668at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000243">
        <property type="term" value="C:commitment complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030627">
        <property type="term" value="F:pre-mRNA 5'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000395">
        <property type="term" value="P:mRNA 5'-splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000064">
        <property type="entry name" value="Putative pre-mrna-processing factor 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059164">
        <property type="entry name" value="HAT_PRP39_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204">
        <property type="entry name" value="PRE-MRNA PROCESSING PROTEIN PRP39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204:SF5">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23241">
        <property type="entry name" value="HAT_PRP39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23240">
        <property type="entry name" value="HAT_PRP39_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="420" mass="45797" checksum="46AA4DA082ECFF49" modified="2009-05-26" version="1" fragment="single">SSVEKIRAVYDAFLAEFPLCYGYWKKYADAETRLAGGAKTGEVYERGVAAVPYSVDLWTHYCAHAVGARADADHVRGLFERGLAYVGTDWLSHPLWDAYVDFEQNSGCGSPRHVAEVYTRVLQVPSRELDRYWTKFCEYVEGRKADALASEDELASIAAEVRASAPPAAAATGAGGGDAATGNGAEEAAAAAAEAAATADPGKDAKTIKFREARRALYETASAHRAIREPFELLIKRPYFHVKPLDDAQVANWERYLSHEESVGDAASVVRLYERCLIPCASYPALWLRYASRTERDQGVEPARAVLQRATRVFVKRELDAHLALAAFEERAGDVAAAREAHARITEEVAPGSIRAAVAHANFERRVGRAEDAKAVYERAMAVERSKEGAETPTYGCLVNQYAAFVAEALGDPAGARDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZT2</accession>
    <name>C1MZT2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60842</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061273.1">
        <property type="nucleotide sequence ID" value="XM_003061227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZT2"/>
    <dbReference type="GeneID" id="9686448"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60842"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="353" mass="38441" checksum="8CD2EC4A9E15F95F" modified="2009-05-26" version="1">MSRYGDRGSREEFTIEDIARGRTIMASDLDKSFEQVFMCNKAHGDALVRAFRNKKYPRRILVHGNMIVSVKIDDRGFVVHKWTKKIIDLKQVYLVVKDSRKIYQLALEFAQRPGEKKAFCDVLQFDPGTSRQFTQLISSRRKELLRDGPGGGGGPSSGRFSDKYAHERSASGGGRGDDVPTMTLAELDAQGSGPPSAMAAAIAKAQQRGGAQQQQQQHIPEHSAFTPASPTRGDDPFNGGLNSSIPPQPHSPVGNQDSTAGDPFGQMMQSVNQNGHQMQTLFSPSPGGAQPASVGNGGAVVDPFAAPNPYGSQPQSMRQNPLLAQQQQQQPLVDPFAQPQQQQQQQKSFNPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZT7</accession>
    <name>C1MZT7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_48127</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061009.1">
        <property type="nucleotide sequence ID" value="XM_003060963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZT7"/>
    <dbReference type="STRING" id="564608.C1MZT7"/>
    <dbReference type="GeneID" id="9686717"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48127"/>
    <dbReference type="eggNOG" id="KOG1465">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3574">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6415790at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008521">
        <property type="term" value="F:acetyl-CoA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035348">
        <property type="term" value="P:acetyl-CoA transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778:SF9">
        <property type="entry name" value="ACETYL-COENZYME A TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="534"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="562"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="593"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="644"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="682"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="715"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="745"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="850"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="389"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="890" mass="94174" checksum="0DAAF6B7B34B1B53" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0A9</accession>
    <name>C1N0A9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50951</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061602.1">
        <property type="nucleotide sequence ID" value="XM_003061556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0A9"/>
    <dbReference type="GeneID" id="9687041"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50951"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004864">
        <property type="term" value="F:protein phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007062">
        <property type="entry name" value="PPI-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398:SF20">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398">
        <property type="entry name" value="PROTEIN PHOSPHATASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="249" mass="25971" checksum="7CF8FB68B78709B7" modified="2009-05-26" version="1">MATAAATTDSAKRKHIVWNEQNLSYNEANKSVRTLPDDRSPPAVVEARRRSTDRSSATPPPFVVLTPSPPLPSPSQAKMKIDEPDTPWASPPRELFEDPAADADADANAINADADAKPAVALDDVAARLEEIESGGGAAGPGTSPGTSPGKGAGDGGEWESSDDEDATAEKSPKQRPKLSFPDPREAPGGGGGGGGGELGEEEGGGAFDDVDKVLTARLFEAQRKAHQCTFRGVMAQGRSLLEEEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0B1</accession>
    <name>C1N0B1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_48194</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061603.1">
        <property type="nucleotide sequence ID" value="XM_003061557.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N0B1"/>
    <dbReference type="GeneID" id="9686803"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48194"/>
    <dbReference type="eggNOG" id="ENOG502QQZZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WHARGAI"/>
    <dbReference type="OrthoDB" id="18797at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00267">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00838">
        <property type="entry name" value="MPP_superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32114">
        <property type="entry name" value="ABC TRANSPORTER ABCH.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32114:SF2">
        <property type="entry name" value="ABC TRANSPORTER ABCH.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13558">
        <property type="entry name" value="SbcC_Walker_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="151"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="4">
        <location>
            <begin position="571"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1093"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1243"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1295"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="922"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1095"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1258"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1276"/>
            <end position="1289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1578" mass="164495" checksum="8213C527F00CD393" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0H3</accession>
    <name>C1N0H3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Geranylgeranyl transferase type-2 subunit beta</fullName>
            <ecNumber evidence="9">2.5.1.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_44694</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="9"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061640.1">
        <property type="nucleotide sequence ID" value="XM_003061594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0H3"/>
    <dbReference type="STRING" id="564608.C1N0H3"/>
    <dbReference type="GeneID" id="9686829"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44694"/>
    <dbReference type="eggNOG" id="KOG0366">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VKRCQCP"/>
    <dbReference type="OrthoDB" id="5428259at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02894">
        <property type="entry name" value="GGTase-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000012">
        <property type="entry name" value="Geranylgeranyl transferase type-2 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026873">
        <property type="entry name" value="Ptb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="11">
        <location>
            <begin position="33"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH54270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="345" mass="36891" checksum="1CE75F839F4E8381" modified="2009-05-26" version="1">MPDEDPTPASASASASASTSRGGVASIPPSRLLSSLHADFIQRASSDDDAIESALTDHLRVSGAYWGLTAMALLGRLDEMDRDGVLAWLARCYDAKKGGYGGNEGHDAHLLYTLSAVQIYALFDRMDLVDADAVAAFAGSLQRDDGSFAGDEWGEIDTRFSYCALCLCKLCGRMDAIDVDAAAAFVDRCKNWDGGYGAEPGGESHAGQIFVCVAALEIAGGDAPGTIDREALGWWLCERQVKAGGLNGRPEKLPDVCYGWWVLSALSILNKLEWIDADALARFILDAQDGEKGGIADRPSDEPDVFHTFFGVAGLSLLGFEGLRRIDPTYALPADVVQRMGLRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0K2</accession>
    <name>C1N0K2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_51051</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061655.1">
        <property type="nucleotide sequence ID" value="XM_003061609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0K2"/>
    <dbReference type="STRING" id="564608.C1N0K2"/>
    <dbReference type="GeneID" id="9686843"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51051"/>
    <dbReference type="eggNOG" id="KOG0068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VQMAEYV"/>
    <dbReference type="OrthoDB" id="496145at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05300">
        <property type="entry name" value="2-Hacid_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="82"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="177"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="35575" checksum="FA64D3DB886F4658" modified="2009-05-26" version="1">MGEILAAPCASSSSSPSSSSRGDGSSHATSERDGRVAWLHSGSAGVEHILAVPRVRDAVAPLTNARGAFSASLGEWALFASLWFAKKVHAMRASQAKGEWMRDTVGMLQGKTMSIVGYGDIGRACAVRAKAFGMKVVALRRDPSKARSTSNWSPYDRGGVVNASLARFPTHRDRPAADDTSSVRSDPIQAEGDFVVLALPHTPETEARSIHWSPYDRGGVGLIDASMIASMKPTGVLVNVGRGAVVDEDALVDALTREKIKGAALDVTATEPLPAGHAFYALENCLMSFHCADLTEDYHELTMTTFIRHARAYVGEEEGDDAAWNVVSKEKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0L9</accession>
    <name>C1N0L9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_51069</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061665.1">
        <property type="nucleotide sequence ID" value="XM_003061619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0L9"/>
    <dbReference type="GeneID" id="9686850"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51069"/>
    <dbReference type="eggNOG" id="KOG3710">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MTAWIND"/>
    <dbReference type="OrthoDB" id="441695at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071456">
        <property type="term" value="P:cellular response to hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051559">
        <property type="entry name" value="HIF_prolyl_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907">
        <property type="entry name" value="EGL NINE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907:SF26">
        <property type="entry name" value="HIF PROLYL HYDROXYLASE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="331"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="163"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="445" mass="46167" checksum="CA888FB0BE4E72ED" modified="2009-05-26" version="1">MATATARASTPRAAAAPPSPRALSRRRRARAPRRAVPARARVATTDEDASASRRPCATLRDARATSAPLADALGDGPDAVPDGPAVFALLLRGDSGDGDDDVAYVGASKRAREAIAAAARSLACSSSELRVARASLPKASRKPALRAAAAAWIAELGRVPSGNAAEDEAEAGGAGGGGGVEEGARERPTRRGRKATMADVARVVISADATKALCEDGFVVLDDVLPLEFFAAARKACEALKADGKMEALGQDGRDDLVGVLDAAALPRGGSAYGGVTPLAELLLAIPDALRARAGGSGGEDDKENGRFKGVTKKKTTAAEETRARLKTATPPPRLMLANYPGSGARYVSHLDNDPNDPGHLEGEIGSRACDRAVTAIVYMNDGWEESRGGCLRIVRRSENGGGASGAVDVAPSEGRLVLFDCRRVPHEVLPAHHTRWAMTAWIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0P9</accession>
    <name>C1N0P9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_51103</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061428.1">
        <property type="nucleotide sequence ID" value="XM_003061382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0P9"/>
    <dbReference type="GeneID" id="9686868"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51103"/>
    <dbReference type="OMA" id="MANRMAC"/>
    <dbReference type="OrthoDB" id="424610at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF5">
        <property type="entry name" value="FERULOYL ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912301" evidence="3">
        <location>
            <begin position="25"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="382" mass="40108" checksum="4536F7749D19E1C3" modified="2009-05-26" version="1">MRAAVFSPVVVLLFAASVAPRVSAGGVDAQGAATPPPPLEGVRLNVPIPVVPDVEVFTPSSYSPTGAKKPLLVFLHGFCLPDAEQQEYSFTGSRASATTPPRQQTLSQVGLRDLVETEDFVYVTPTAPHATRYCALCNVGEDSPNVGDRLTVRWINSTLARTAPAFACPAWDGSDACCNPELGGRGDDASFVKAVVDAVVDRYAIDTSRIYLMGIATGGFMANRMACEYADVFAGVATFAGGVWADADKCVAGGGGENGVTNVLNVHGDGDLTVPIGGGVNFAGVPFPSADQTVDTFARKFGCDALPREVAAADDGDDFSLPSDGRRDVDVSVTKFEGCGADGAYVVEQWTLAGVDHFMQEKTSRGVFKAVVQWLTSKRRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0S5</accession>
    <name>C1N0S5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_62915</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061442.1">
        <property type="nucleotide sequence ID" value="XM_003061396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0S5"/>
    <dbReference type="GeneID" id="9686882"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62915"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="171" mass="18929" checksum="A7A8AA1FA955505D" modified="2009-05-26" version="1">MNQKMEWSIDRSVVRSNRRTRRERGRGARARRERGAARVRRATLAVESAGAPRTTDASPERRRERRGSRAARSNDDARRGRALRGAKTGRAALCGRDCGGAGGVGRPSSARLAGGKIVDWRRWSWSERQPASCVVNQFQSSRARRVRRSALSTSWACTRRNGRADAGPGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N135</accession>
    <name>C1N135_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_51246</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061740.1">
        <property type="nucleotide sequence ID" value="XM_003061694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N135"/>
    <dbReference type="GeneID" id="9686942"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51246"/>
    <dbReference type="OMA" id="ADCNQAG"/>
    <dbReference type="OrthoDB" id="10636730at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="222" mass="23392" checksum="EF97374A237DE2E7" modified="2009-05-26" version="1">MAPPRALRILHGGPIAREVASHVAAAANAAADGALAAEVFELAEYPDAGLDIVRLGVVDDDDDDARVDARSRDVIYVLVVETAEFENPADESVTFIRDCLAASKKNRAAGAAAGDDDRASPSRWRIRRVDDDDVGSAAPVPVAYAVVAVGDTDAMPERAAFRSNQNTAADCNQAGALADDAVKRLGGTRVTPRRYLDAARDELDVAAAAWCRDTLLPAVRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1D2</accession>
    <name>C1N1D2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_7107</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061793.1">
        <property type="nucleotide sequence ID" value="XM_003061747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1D2"/>
    <dbReference type="STRING" id="564608.C1N1D2"/>
    <dbReference type="GeneID" id="9687232"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7107"/>
    <dbReference type="eggNOG" id="KOG1667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PEGSCTY"/>
    <dbReference type="OrthoDB" id="10261079at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1130.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007051">
        <property type="entry name" value="CHORD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043316">
        <property type="entry name" value="RAR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47895">
        <property type="entry name" value="CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN RAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47895:SF2">
        <property type="entry name" value="CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN RAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04968">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51401">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CHORD" evidence="5">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="CHORD" evidence="5">
        <location>
            <begin position="157"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="221" mass="23452" checksum="8F43F4820C224B52" modified="2009-05-26" version="1" fragment="single">KYLCQRVGCDAVYDASENAAGSCRHHPGAPTFHDGTKRWSCCGKSSHDFGEFMSFPGCATGRHTQRKPKKTRAPPAPAPALAPIPMPTSAEARAGAAASPAASPAAACARCRQGFFCSDHAASAEAQAAYVAPTIKPPSNPAADTVVCADPDAVQICRNKGCGESYRERDNADDACLHHPGPPIFHERKKGWACCDVMCYDFDEFMSVKPCARGRHCAAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1E5</accession>
    <name>C1N1E5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_51371</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061802.1">
        <property type="nucleotide sequence ID" value="XM_003061756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1E5"/>
    <dbReference type="GeneID" id="9686990"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51371"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001510">
        <property type="entry name" value="Znf_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00645">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01336">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50064">
        <property type="entry name" value="ZF_PARP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PARP-type" evidence="7">
        <location>
            <begin position="5"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="102" mass="11149" checksum="E001D31047F52017" modified="2009-05-26" version="1">MPKAYVVERAPNARASCKGVCGMKFEKDVLRFCGKSGKRQSPAWTHLSCAPAATFDAAIATCGDLGSIPGVKELEIEDTMRRARENARKREERLAARRSPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1G4</accession>
    <name>C1N1G4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51393</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061560.1">
        <property type="nucleotide sequence ID" value="XM_003061514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1G4"/>
    <dbReference type="GeneID" id="9687000"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51393"/>
    <dbReference type="OMA" id="GHAPEFS"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="225" mass="26415" checksum="24C1D838762C7673" modified="2009-05-26" version="1">MRARQAESAAKARAHELKVRAAAIAAREKLREEQKAMAEHYEQEQARLTTLHEAAAKKRRAEIRAEDERRKELDRQREIDKRAHMKALREKQRAREAAWAARMESEDGERTTGMAVEIREFQKRMDSARRADSARRRDAQRRERREAREKEAEYREHLQRIADEQAEKAAQRLKEIRAAQKKAARDAAKKQAERVERLKLEEEAARSKDEEMKTRIAARKGMLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N221</accession>
    <name>C1N221_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_6556</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062216.1">
        <property type="nucleotide sequence ID" value="XM_003062170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N221"/>
    <dbReference type="STRING" id="564608.C1N221"/>
    <dbReference type="GeneID" id="9687655"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6556"/>
    <dbReference type="eggNOG" id="KOG0895">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NEANSEH"/>
    <dbReference type="OrthoDB" id="47801at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23810">
        <property type="entry name" value="UBCc_BIRC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF39">
        <property type="entry name" value="BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="162" mass="17963" checksum="57F7645F6FDFA889" modified="2009-05-26" version="1" fragment="single">LVRVDERRAVQWTILITGPEDTPYDCGAFLFDAFFPSSYPTSAPLVKFRTTGGGRVRFNPNLYKDGKVCLSLLGTWSGAKGETWDAASSTMLQVIVSIQSLILCAQPYFNEPGYERTIGTPEGDRQSSQYNAAIREHALRCAMIDQLKKPPAPFAEAIRAHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2L6</accession>
    <name>C1N2L6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51578</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062107.1">
        <property type="nucleotide sequence ID" value="XM_003062061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2L6"/>
    <dbReference type="STRING" id="564608.C1N2L6"/>
    <dbReference type="GeneID" id="9687337"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51578"/>
    <dbReference type="eggNOG" id="ENOG502RZCC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="543798at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="300" mass="32710" checksum="2166DD1D1DBE6BBF" modified="2009-05-26" version="1">MPPATTPSSPPPSLSRMTICGSRGDSLSLGPFLDRLPRELLEEKILKALPTTALTLFGRTCRGAREMMIESGDRYHGDGRSRPEGCPTCGKFSVYDFVTSVPLLAWALSNGLKVDATICGNAAFHGALDVLAFARENGIPWDLDTCDGAAQGAKLDVLQWVIDRGCPLEMSACEVAAEVGHLDVLKFLRARDPPCPWGPRVAAGAAANGNLECLKWLHENGCEWDERVLKLGSRHNHAELCAWAVSAGAPEWHSDSEDEDDEEEVDEEGVDDVGDEFAEDEEVDELEDTEVDDENEAEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2R6</accession>
    <name>C1N2R6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_20863</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061922.1">
        <property type="nucleotide sequence ID" value="XM_003061876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2R6"/>
    <dbReference type="STRING" id="564608.C1N2R6"/>
    <dbReference type="GeneID" id="9687571"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20863"/>
    <dbReference type="eggNOG" id="KOG0048">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF25">
        <property type="entry name" value="MYB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="50" mass="5732" checksum="04B59CB44AFCB4C6" modified="2009-05-26" version="1" fragment="single">LRRDTFTPAEERTLLAAYKKLGNRWAAIAKVLPGRTDNAVKNHLNSKLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3G7</accession>
    <name>C1N3G7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pseudouridylate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RSU</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_70674</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062609.1">
        <property type="nucleotide sequence ID" value="XM_003062563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3G7"/>
    <dbReference type="GeneID" id="9688049"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70674"/>
    <dbReference type="eggNOG" id="ENOG502QQ1B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SMEFAPF"/>
    <dbReference type="OrthoDB" id="440619at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF2">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="6">
        <location>
            <begin position="92"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="5">
        <location>
            <begin position="158"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="356"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="386" mass="40467" checksum="C6ED25E6871AA207" modified="2009-05-26" version="1" fragment="single">MASPAARAALTRVVPSAFGRLSRRGARGRGALDGVDPRGVATSSSSGEKKKRVGGVAVRATTRLSWSSGARSFAAAAHVDDGELPPHPIQTQRVSKLMSQRGMASRREAEALIDRGDVIVNGGEVATRGMKVAIDATIDIAGDSDGGANALLAKKVTVVLNKPPGYVSNLPSRGEREASELITPRNAIYHHSTGGGVVGGGADADAATRRKLEDVCRDARALNVCGRLDKDSRGLLVLTTDGVLARAIVGGNEIPKVYEVVVDAIATREQLAALNGPVALDGERLLPMRVETLEGTTLRFELRQGKKRQIRRLCEGLALRVLDLRRVHVGTCDVGDLPEGRWRLMSEAESASIRAAGLAAAGNDPNRGGRGGRGGRGGRGRGRGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3H0</accession>
    <name>C1N3H0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52168</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062375.1">
        <property type="nucleotide sequence ID" value="XM_003062329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3H0"/>
    <dbReference type="GeneID" id="9688051"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52168"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="184" mass="19771" checksum="2B82B39554689D57" modified="2009-05-26" version="1">MPPRRWHHETGGELAHIVSSLLHGSGPPPVLVGITACMVCTALSSLGVGRWHEKMWRQRRADADVLASALRREAEEEILNASMATSSAMDTARDESDMSFVVESADDDDETMSIRGSETSASEAGSDVAWTTTTPSSSRATKGRDFKCAPPRGSAKKPPSRLARHSPNSVLGDLTNVGVSSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3M4</accession>
    <name>C1N3M4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_52228</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062398.1">
        <property type="nucleotide sequence ID" value="XM_003062352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3M4"/>
    <dbReference type="GeneID" id="9688082"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52228"/>
    <dbReference type="OMA" id="SSINYAW"/>
    <dbReference type="OrthoDB" id="74529at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="237" mass="27244" checksum="5D31EE7FF2807352" modified="2009-05-26" version="1">MGACATKCFARDPPLRSSYPPTRSAEDEYRVAMLVLPLVEDVKTRVVASRLSRGWRDADKSAASLPAKLDGLDLYPNNPRNTYGRVVTASYEYVMRHEGVLDLPKERVEALLTRFWETPPTHRLFKDTHYFCQRAAYIGNLELLQWLREHDYPWSTATCASAVFGSQLEVLRWALANGAPWDKYETTFSRPGNRENVITWLLNPRKGDPRPSDWEKYLELLREAGKRQVSKRLVARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N447</accession>
    <name>C1N447_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_42328</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062482.1">
        <property type="nucleotide sequence ID" value="XM_003062436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N447"/>
    <dbReference type="GeneID" id="9688171"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42328"/>
    <dbReference type="OrthoDB" id="424834at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910748" evidence="2">
        <location>
            <begin position="23"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="415" mass="42149" checksum="B8E4387A81E497AD" modified="2009-05-26" version="1">MALPPRLRRGVVCAALLAIVLACNHFCRDAPGTIEEQLRADPSLDVTPTRFSIMTALYFAPSALVPLVAGGVSSLPKHHAAYVSPQRAFATVAAVGAAGNVLSAAGASSGSFAALACGRAVAGSVYEAIDMTPLGFVPALLPGLWGTASGFITGALRLGSVLAFAALPRIYEQSGGGADGGGGVAAVFWFAACVGVVMWPLAAIVREVATRAAFDASPHWGGGSLGARLRAWLSDGGDGGDDDDDGGGGAASGGGGGEALKAFESSTGGGGGEAPTPPIASSIATAVAAVVSAVETVPRSFWLYALSGTCMYRRRRRGRDVAAADELMLLPELALAVLSVPIGVAVDRAKLSFRAQQLGFSVCALMITLAHAALLFGGDEVAAVFFLGVGYACCNQVRSIHWFPYDRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4S7</accession>
    <name>C1N4S7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_52666</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063048.1">
        <property type="nucleotide sequence ID" value="XM_003063002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9688285"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52666"/>
    <dbReference type="eggNOG" id="KOG0241">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VEMSAFE"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="5"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="167"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="257"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="346"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="471"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="725"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="919"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1046"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1168"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="502"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="348"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="487"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="734"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="924"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="968"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1063"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1173"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1195"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1306"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1385"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1533"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1548"/>
            <end position="1560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1560" mass="165580" checksum="8F278EDF4E76F279" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4V3</accession>
    <name>C1N4V3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52691</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063061.1">
        <property type="nucleotide sequence ID" value="XM_003063015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4V3"/>
    <dbReference type="GeneID" id="9688298"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52691"/>
    <dbReference type="OMA" id="GNSSHER"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="185" mass="21968" checksum="AA53A1F27947ADCC" modified="2009-05-26" version="1">MSYHDTSDEEGEIVAAPAPAPATDVAGKRRGRSRSGSPPRHQSKRAARMDDPSSYRDDDRDRDRDRDRDRDRERDRDRDRDRDRDRRRGDSRDRDRDRRDRERRDPGDRDRDRDRRADPRDSARGGERGREKPREQDPRDSHKPGTARKVVVVKRGGNEARRDDDRDRDRDRDRDRGAFYTLVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N616</accession>
    <name>C1N616_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 18 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_22528</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063458.1">
        <property type="nucleotide sequence ID" value="XM_003063412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N616"/>
    <dbReference type="STRING" id="564608.C1N616"/>
    <dbReference type="GeneID" id="9688696"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22528"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SGIMIWE"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.30">
        <property type="entry name" value="(Trans)glycosidases - domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910763" evidence="1">
        <location>
            <begin position="29"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="2">
        <location>
            <begin position="51"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="362" mass="38756" checksum="24AEA37EF14128E0" modified="2009-05-26" version="1">MASRGGGAGATARLALLLVVLLLLPGRGAPDTAPSSSFASPSPGAPASSPFAVVAYLPEWRFASTDWDAVCVNVTHLILFSLEVTDDGSLTSLDRFPSPEAMTTLRAAAAKRGVKLLLSLGGHGRTRGFPIVAVEKTKRRRLARTLASFCATHGLHGVDYNWEYPASPAEWNGMFALLRTTRKVFDGSPQRLTITMAYYPDGRQERELKRGGAEEHVELLHAMSYDHPRGSHSSTALARAAIRNAEEAGLDARKITIGLPFYGRHVETGEWKTYAELDAAHGVSAEPSKDEAGGYAFNGADTIRLKTSEAKAAGTGGVMIWEAGQDLHPSHARSLLAVVAAEAWGDEGKNAVGEKKRAREEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N853</accession>
    <name>C1N853_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53955</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064022.1">
        <property type="nucleotide sequence ID" value="XM_003063976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N853"/>
    <dbReference type="STRING" id="564608.C1N853"/>
    <dbReference type="GeneID" id="9689650"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53955"/>
    <dbReference type="OMA" id="GWCLIDA"/>
    <dbReference type="OrthoDB" id="496720at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01100">
        <property type="entry name" value="SHIKIMTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="300" mass="32467" checksum="3C512881C421ACDE" modified="2009-05-26" version="1">MASASPASSAATTVRATARWRPTRRSLSLSSTPRAALRARGRGRRGGGIDDDPAIRHRHRGKKGVGAATENGGEHAGGANDDDDASPLPPPNNLILIGGRGCGKSALCRRLVALEPRFELFVLDDIVVEDAGKSIPKIVEEDGWRAFRDLEFDACRKTAIAAGRGWCLIDAGGGVVVDLDEHGNEVYSERKVDALKRNGQGKIVYLKRAVSYLTRRITGDKNRPSLSEKWTFGEIMRRRAPMYERAADYVCDGSGGALEKDVKTKNEIKREVIEWFYDVSGSGVLRAEGESGGEELFGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8C4</accession>
    <name>C1N8C4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54033</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064244.1">
        <property type="nucleotide sequence ID" value="XM_003064198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8C4"/>
    <dbReference type="GeneID" id="9689499"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54033"/>
    <dbReference type="eggNOG" id="KOG3940">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="265955at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026319">
        <property type="entry name" value="ZC2HC1A/B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13555">
        <property type="entry name" value="C2H2 ZINC FINGER CGI-62-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13555:SF68">
        <property type="entry name" value="ZINC FINGER PROTEIN 474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13913">
        <property type="entry name" value="zf-C2HC_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="395" mass="42662" checksum="F2D36408FCC36A7A" modified="2009-05-26" version="1">MTSKPRLLTCYVCAREYGTKSIAIHIPQCRRTFEAREALKRDARDRRRCPDPPPGYMDLIDAIGASRSLGETLAAASLTPPSPGSLSTRAKGSLVVDAINDAAYRRWSDEVLRKCERCGRSFNPDAYTRHAARCAGKGLSPARRSARAAASRGGKVVDVGTKVAAKPRSPAKAPRARTIAFDDDDDDDEVCGDSGDDAGDDAGDDSARCASDEDAPHGRPVLSGVALDTTHAPSLGAVRVYENEDWYLARVSVPDCDDERFVVEISNGDRGDRAEIVVEGVVTGAADGAVERAVPVSISNPGVCVDSYFTPVLGPGTYLPELPNPGRWSRKFALPGPVVLELRDVDGRLPPGETRTHYKIVHQQSRTLELYFWKEKPSDVLSPVRSPGVDRGFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8D9</accession>
    <name>C1N8D9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43305</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064066.1">
        <property type="nucleotide sequence ID" value="XM_003064020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8D9"/>
    <dbReference type="STRING" id="564608.C1N8D9"/>
    <dbReference type="GeneID" id="9689507"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43305"/>
    <dbReference type="eggNOG" id="ENOG502QPJI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YVQCALG"/>
    <dbReference type="OrthoDB" id="550558at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052963">
        <property type="entry name" value="Pantetheine_PDE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36492:SF2">
        <property type="entry name" value="[ACYL-CARRIER-PROTEIN] PHOSPHODIESTERASE PPTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="447" mass="48808" checksum="8E92AB4E52129FEB" modified="2009-05-26" version="1">MRRSASAPVVAASSAPVETRAEYYSLIVNAINDAAAKAPPPNRALPPPPSFASSSFAADRYSRDGRWTVHAISDVHADMKDNMRWAKRLPRYPPRHALIVAGDVATAVDCIAATLRAFKEKFEEVFYVPGNHDLWSPAPPNDWSHAGHPANSIGKLRHIVDVCASLGVRVAPTILPGAAGGKSALEEETPEASQSSESEEEEDYFGKIGGSRRRTKEDTLAKSNTPPSNETVPAATTAASTDQSPNDVLILPMQSWYKSTFYGGDHPTDSFHGREDDETFSSREKHFDVGCCWPPAIGYANEPRNSHARGIADFFLRCNEGIGAAGTKRVVLDRVGVPPAVPESSVDVVSFSHFIPHPRLYRGHPRLSKVMGCEELGAQVRELRSVCHVFGHSHMDVDEVIGGCRYVQCALGYPNERWGGSVTPTKVWPRGRRRETSAWADVDSWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8L0</accession>
    <name>C1N8L0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_54129</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C69 family. Secernin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064103.1">
        <property type="nucleotide sequence ID" value="XM_003064057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8L0"/>
    <dbReference type="STRING" id="564608.C1N8L0"/>
    <dbReference type="GeneID" id="9689726"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54129"/>
    <dbReference type="eggNOG" id="ENOG502RZ1C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GNMNEHQ"/>
    <dbReference type="OrthoDB" id="5175656at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070004">
        <property type="term" value="F:cysteine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005322">
        <property type="entry name" value="Peptidase_C69"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994:SF17">
        <property type="entry name" value="LD30995P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994">
        <property type="entry name" value="SECERNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03577">
        <property type="entry name" value="Peptidase_C69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910683" evidence="3">
        <location>
            <begin position="46"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="602"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="606"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="630"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="640"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="651" mass="70107" checksum="BE4AF73FFA401607" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAH9</accession>
    <name>C1NAH9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66084</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064962.1">
        <property type="nucleotide sequence ID" value="XM_003064916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAH9"/>
    <dbReference type="STRING" id="564608.C1NAH9"/>
    <dbReference type="GeneID" id="9690403"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66084"/>
    <dbReference type="eggNOG" id="ENOG502S9FE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2011676at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF10">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="86"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="307" mass="34771" checksum="7B2FD707C950443B" modified="2009-05-26" version="1">MIHRETLVYDVKHMCSFQRRRLPKKKVSTSTLIFVLLCITLLSQVAPGIVMRRDVHPDVYTRFAGSSKSWDAYLPHKLSTPDFCTNKNQLALDWFRELYNRPAAIMPARCDSARRVGNIGDGGKYVCLSPLQSHRCVVYSLGSRLDFSFELALQNMTGCEVHTFDCTVGVPGSGVVPEGINFHPWCAGPHDEIKFISSDLGHTGEKGQYYTLQSIMNSLAHDSIELLKMDIERHEVEVISTLAKHTAPSQLVFETHLHNAYGMWGRPVNPNEWNSIWSRLESLGYGVFSYEPNDICLCCSEWSLLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAL7</accession>
    <name>C1NAL7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_11237</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064927.1">
        <property type="nucleotide sequence ID" value="XM_003064881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAL7"/>
    <dbReference type="GeneID" id="9690427"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11237"/>
    <dbReference type="eggNOG" id="ENOG502S32G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="41052at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051842">
        <property type="entry name" value="uS12_prolyl_hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117:SF0">
        <property type="entry name" value="PROLYL 3-HYDROXYLASE OGFOD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase" evidence="1">
        <location>
            <begin position="108"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="210" mass="24391" checksum="05C2EA06EC0863B1" modified="2009-05-26" version="1" fragment="single">LANQHRERFRNADPFPHVYVDDFLEPNFVRAVDDEFAGKNQKKKVHCFHKAGDENEGKKTAVLDESVMGPNTRAVFGLLKTSLFVEFLERLTGIDDIIPDPHYRGSGLHQTEPGGFLRVHADFNRYERFGLDRRVNVFLFLNEGWDAGWGGALELWPRDMSSCKQKIQPLFNRLVIFRTTDFSYHGYTDPIRSPFPRRSVSMYYYTNGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGF0</accession>
    <name>C1MGF0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_70259</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054761.1">
        <property type="nucleotide sequence ID" value="XM_003054715.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MGF0"/>
    <dbReference type="GeneID" id="9680994"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70259"/>
    <dbReference type="eggNOG" id="KOG1809">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PRYSCVA"/>
    <dbReference type="OrthoDB" id="428159at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF130">
        <property type="entry name" value="PROTEIN SORTING-ASSOCIATED PROTEIN, PUTATIVE (DUF1162)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Chorein N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="379"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="564"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1141"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1416"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1489"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1909"/>
            <end position="1935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2123"/>
            <end position="2152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2606"/>
            <end position="2627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2655"/>
            <end position="2712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3058"/>
            <end position="3082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3185"/>
            <end position="3209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3428"/>
            <end position="3453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3660"/>
            <end position="3770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3981"/>
            <end position="4013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4098"/>
            <end position="4117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="516"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="565"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1508"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1909"/>
            <end position="1919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1920"/>
            <end position="1935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2130"/>
            <end position="2150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="2606"/>
            <end position="2615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="2699"/>
            <end position="2710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3062"/>
            <end position="3071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3672"/>
            <end position="3683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3687"/>
            <end position="3728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3735"/>
            <end position="3749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3758"/>
            <end position="3770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3997"/>
            <end position="4013"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="4168" mass="430283" checksum="70531BAB8ACD6AA8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGT3</accession>
    <name>C1MGT3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Endonuclease III homolog</fullName>
            <ecNumber evidence="12">3.2.2.-</ecNumber>
            <ecNumber evidence="12">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <shortName evidence="12">DNA glycosylase/AP lyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">NTH1</name>
        <name evidence="15" type="ORF">MICPUCDRAFT_30626</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="12"/>
    <dbReference type="EC" id="4.2.99.18" evidence="12"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055376.1">
        <property type="nucleotide sequence ID" value="XM_003055330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGT3"/>
    <dbReference type="STRING" id="564608.C1MGT3"/>
    <dbReference type="GeneID" id="9680260"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30626"/>
    <dbReference type="eggNOG" id="KOG1921">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KDPITHA"/>
    <dbReference type="OrthoDB" id="2099276at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000703">
        <property type="term" value="F:oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000005">
        <property type="entry name" value="Endonuclease III-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03183">
        <property type="entry name" value="Endonuclease_III_Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030841">
        <property type="entry name" value="NTH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286:SF1">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="14">
        <location>
            <begin position="95"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH60628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="298" mass="31920" checksum="5C73871C1CED1ABA" modified="2009-05-26" version="1">MAGGRKRAHVKIEVDDAGDDEDAKATTPKAAAAKTKKKTPPFSPPEDWRDVLAAIKRQRAVGGAPVDTMGCEKISEDAAPDDRGRRFVTLVSAMLSSQTKDPITHAATARLVKHGCTPENIAATSAEDLAAIIRPVGFHARKGQYLRDAARACVERHGGDIPSDVDGLMALPGVGPKMAYLVMNVGWGVPSGICVDVHVHRIAERLGWVPSVAFTSNGTPRKNRTPEDTREALEAWLPREEWIEINPLLVGHGQLTCAPKAPKCGECAANAMCPSAFKDEEARRAKKEEKNAAAEAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGV0</accession>
    <name>C1MGV0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_4867</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MlaE permease family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054841.1">
        <property type="nucleotide sequence ID" value="XM_003054795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGV0"/>
    <dbReference type="STRING" id="564608.C1MGV0"/>
    <dbReference type="GeneID" id="9680281"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4867"/>
    <dbReference type="eggNOG" id="ENOG502QPRJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VFQGYDC"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005548">
        <property type="term" value="F:phospholipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_roteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00056">
        <property type="entry name" value="MlaE family lipid ABC transporter permease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="ABC TRANSPORTER PERMEASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188:SF4">
        <property type="entry name" value="PROTEIN TRIGALACTOSYLDIACYLGLYCEROL 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="251" mass="26687" checksum="DA0F074503EF1EC5" modified="2009-05-26" version="1" fragment="single">LNEWEPPKFVWRTLYTLLLLGLVIKRVVWQRKLNMAQTIQQIARVGPDTLGVAMLTSSFVGMVFTIQFCKEFSKVGLTRVIGGLLGLAFTRELTPVICAIVLAGRVGSAIAAELGTMQVSEQVDQLRTLGSDPVDYLVAPRVVACALSLPILSVVSFTIGMAASILLADLRYGISPNAIVDSAAKYLETSDIGVMCVKGLAFGGVIATISCGWGQTTTGGAKGVGESTTASVVISLVAIFVVDFFLSMIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHA0</accession>
    <name>C1MHA0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase III subunit RPC6</fullName>
            <shortName evidence="6">RNA polymerase III subunit C6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_43793</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055453.1">
        <property type="nucleotide sequence ID" value="XM_003055407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHA0"/>
    <dbReference type="STRING" id="564608.C1MHA0"/>
    <dbReference type="GeneID" id="9680911"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43793"/>
    <dbReference type="eggNOG" id="KOG3233">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QGCTIRD"/>
    <dbReference type="OrthoDB" id="613763at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000116">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit RPC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000237">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit RPC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007832">
        <property type="entry name" value="RNA_pol_Rpc34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016049">
        <property type="entry name" value="RNA_pol_Rpc34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12780">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05158">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028763">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR028763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="294" mass="32828" checksum="6FAE8D10FBC850EA" modified="2009-05-26" version="1">MAEAAILEQCRLHPQGIPDADLAMEIAHIPVNERASAINALLSSRKIQVYKDGDSLIYREVQKDEAVKFKGLSSEDLLVYQIIQSSGNTGIWTKELKQKSNLPQTQITKIFKVLEARKLIKSVKNVAQQNRKVYMLFELEPSREITGGAWYTEHEYDAEFISVLREQCDKFINSRGKATLDDVWDFVKRAKLSNVDLGKEEVLQIVNTLVYDGKIDAIEVPDPNFKPTAKKGKDIDAGHEGEDYSPAAIPIPSESALTNVPCGLCPVFEECVPGGLISPETCEYMDAWLAQDDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHW8</accession>
    <name>C1MHW8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_8379</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endomembrane system</location>
            <topology evidence="4">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055027.1">
        <property type="nucleotide sequence ID" value="XM_003054981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHW8"/>
    <dbReference type="STRING" id="564608.C1MHW8"/>
    <dbReference type="GeneID" id="9681132"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8379"/>
    <dbReference type="eggNOG" id="KOG4252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KGIFTHA"/>
    <dbReference type="OrthoDB" id="6585768at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="167" mass="18542" checksum="EEDD1E3C2BBEF710" modified="2009-05-26" version="1" fragment="single">EKEVKVVVVGNGGVGKTSMIRRYCRGVFTEDYKKTIGVDFLEKVSYIESVGEDVRLMIWDTAGQEEFDTITRSYYRGAGAAVIVFSTTDRASFDAVRSWKQKLSEEVGDDVATCVVQNKGASHLTPACAVEPGEAETLARELGVKFFRACVKENFNVDNVFDYLVDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ12</accession>
    <name>C1MJ12_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46408</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055230.1">
        <property type="nucleotide sequence ID" value="XM_003055184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ12"/>
    <dbReference type="GeneID" id="9680378"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46408"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="512" mass="53713" checksum="87AE0F9B3757BFCA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKL5</accession>
    <name>C1MKL5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55381</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056406.1">
        <property type="nucleotide sequence ID" value="XM_003056360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKL5"/>
    <dbReference type="GeneID" id="9681708"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55381"/>
    <dbReference type="OrthoDB" id="666364at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="59" mass="6610" checksum="BFE14A67CF4B18DC" modified="2009-05-26" version="1">MLTSVQANTNHSEKKSKISRDRERDVGEQIALGQSKVPSSGERIALFDQRLFDQVLHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKM6</accession>
    <name>C1MKM6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55390</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056414.1">
        <property type="nucleotide sequence ID" value="XM_003056368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKM6"/>
    <dbReference type="GeneID" id="9681713"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55390"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="179" mass="18965" checksum="D30F68471B16AF75" modified="2009-05-26" version="1">MASASTTATRAGPSLPQRVLARRLSLNALASHAARRVAGSRASSSSSSSSSSSAASACAVSSHLVARRAGAALALASAAAVPRGGDLVRTDPLRGRGFDAPRHVARAAGGQGGYLLGGRKSKDRYSDAAARVPPSPEESLDDEENARVRRARFEEEERQRYKNLPVKMKIRYALRRLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML42</accession>
    <name>C1ML42_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_25078</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PRP38 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056109.1">
        <property type="nucleotide sequence ID" value="XM_003056063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML42"/>
    <dbReference type="STRING" id="564608.C1ML42"/>
    <dbReference type="GeneID" id="9681756"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25078"/>
    <dbReference type="eggNOG" id="KOG2889">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QNGYNEF"/>
    <dbReference type="OrthoDB" id="190958at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="189" mass="21537" checksum="316D9D82F67FD963" modified="2009-05-26" version="1">MASSTDPLARSINGLNPQAIIEKITRTKIYESPFWKERCFGVSAATLVDLAMNLRAFGGVYGSSSKATDFLCLTLKMLQIQPDKEVILEFIKNEDCKYVRILGAFYLRLVGKSFEVYQLLEPLLLDYRKIRHQTSQGNFELMHVDEFVSALLTRDNFCDISLPRLTHRQLLETSGQLEPRCGVAVKLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLP4</accession>
    <name>C1MLP4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase family U32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PEPU32</name>
        <name evidence="2" type="ORF">MICPUCDRAFT_70757</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056199.1">
        <property type="nucleotide sequence ID" value="XM_003056153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLP4"/>
    <dbReference type="STRING" id="564608.C1MLP4"/>
    <dbReference type="GeneID" id="9681812"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70757"/>
    <dbReference type="eggNOG" id="ENOG502QVE5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ACRLPYG"/>
    <dbReference type="OrthoDB" id="426032at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020988">
        <property type="entry name" value="Pept_U32_collagenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051454">
        <property type="entry name" value="RNA/ubiquinone_mod_enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30217:SF10">
        <property type="entry name" value="23S RRNA 5-HYDROXYCYTIDINE C2501 SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30217">
        <property type="entry name" value="PEPTIDASE U32 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12392">
        <property type="entry name" value="DUF3656"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase U32 collagenase" evidence="1">
        <location>
            <begin position="529"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1027" mass="110832" checksum="BD49B1DEACBD7C95" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLR9</accession>
    <name>C1MLR9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56248</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056810.1">
        <property type="nucleotide sequence ID" value="XM_003056764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLR9"/>
    <dbReference type="GeneID" id="9682709"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56248"/>
    <dbReference type="eggNOG" id="ENOG502S6QT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FCNARES"/>
    <dbReference type="OrthoDB" id="195555at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049213">
        <property type="entry name" value="DUF6816"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20670">
        <property type="entry name" value="DUF6816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6816" evidence="1">
        <location>
            <begin position="92"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="335" mass="36405" checksum="C145ECF2206C7E35" modified="2009-05-26" version="1">MSALAGAPTPATTAKARVAPRARVSRARAFVARDGADYDFDRRAALLAGGLLASTLALPEPAALAASTSLAERVERRDLSKPVFNKARPGPTRFPDWLEGTWRCTSTFEGFDFPSKNINKNALLKEPTVPGFQKMSLVYVPDVGTSDVEYLVRFVRANDGDGGVCEDRVFNLKSIVDAYLKRPDAVEAVEYDAASDANRVTVRLAPGVSNNAERIELFSNARESETRASDGTFFAAEALRQVTLGYSKDYNKARVVNTDYQHVWSYTPTYESDGSIRRVRCALSTAGYIQPSDAMRLTAMPNLGGGAPVPSMGNMGNASFEPAVLYSHTIVMERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM04</accession>
    <name>C1MM04_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_62347</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057310.1">
        <property type="nucleotide sequence ID" value="XM_003057264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM04"/>
    <dbReference type="STRING" id="564608.C1MM04"/>
    <dbReference type="GeneID" id="9682294"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62347"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MADPEEC"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15241:SF304">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15241">
        <property type="entry name" value="TRANSFORMER-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="9"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="282" mass="31971" checksum="FA77C7C749086D17" modified="2009-05-26" version="1">MGDNRGSATRVFVGGLAWAVDSARLGQRFTEFGPVEFSKVVYESGGQRRSRGFGFVKFATTEARDRAVKDGDGMEFDGRRVNVKVADDIDGSDHQRPPPPRGGDDRGAAPPPRYPPPPERTIPPGPPERAMDYRGGERRRDDWGAPPPRRASYDEPPPREPHYGRGDDPRGYDAPPRREPSSSYDRYERYDDRRAFSRPPSRDRDEQRGERGERGGDRRDWPRDAYDDRRGPERPPPPAGYDRAYDRDRPPPRGAPPRSPPRGPPPRSPPRRAAPTPYDRPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM07</accession>
    <name>C1MM07_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56355</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056856.1">
        <property type="nucleotide sequence ID" value="XM_003056810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM07"/>
    <dbReference type="STRING" id="564608.C1MM07"/>
    <dbReference type="GeneID" id="9682295"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56355"/>
    <dbReference type="OMA" id="AIYMEYP"/>
    <dbReference type="OrthoDB" id="421121at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050498">
        <property type="entry name" value="Ycf3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44858:SF20">
        <property type="entry name" value="SHSP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44858">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="345" mass="36488" checksum="E3D40997BC0A8B3B" modified="2009-05-26" version="1">MASALATASRFATIATRAAASESSVPGPRRSASRVARTRRDLLAAALVVAPFASSSSSSSASSASSSASESAPDLARAIASLQREAADAYDARDFERASDALSSLMALEPSNEIWLEGRAQVYVDASRFRDAIDDYTSLLARAGAGPTAENAGARARYLANRALAHEGEKSWQRALEDDDAALALASDGGFLPDPYVLNSRGSVKSQLGDYAGARDDFLESYDLFQQSKGFRSASGVRSTPRLDGAVYAASNAALALAQLGTDDARATRELRDVARRAPNVADARAALAAVLYAGGETAAAEDAWTSACATNVGCKNYRDAAYVRDVRRWPPRMRAMLEDFLLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM89</accession>
    <name>C1MM89_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_45380</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057358.1">
        <property type="nucleotide sequence ID" value="XM_003057312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM89"/>
    <dbReference type="STRING" id="564608.C1MM89"/>
    <dbReference type="GeneID" id="9682797"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45380"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QVMQYCW"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000060">
        <property type="entry name" value="Serine/threonine-protein kinase isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF261">
        <property type="entry name" value="ZINC FINGER CONTAINING PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="12">
        <location>
            <begin position="138"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="196"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="447"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="450"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH59003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="481" mass="52520" checksum="5058EED5645E5BFB" modified="2009-05-26" version="1">MTPASSKASKEQVALRVLERLKETWPIIAQDPTLEAALKTHFTRLPRRYALDIHNLEDIRSHVRLLERAERTPGAVLCESRGVRLSSVFGDVSNSIGNSLNDMDVAMSSSPSASDGRTLEDQMNEGGVGGKTPLPVFEIAVSGRNRPRMLSRVSASLFDLGLNITEAHVFCTNDGYALDVFVAQGAGEWEIQEAQLSFKEKIASGAFGVLYRGGYCGQEVAIKVLKTGEKSSQEEVYREFAQELSILRKVRHRNIVQLIGAMTKPPRLCLVTDFMKGGSVLQFLHKNAPLKLPQLLKLSGGVALGMDYLHKVSVIHRDLKTANLLMDENEVVKVADFGVARVVAADGAAMTAETGTYRWMAPEVISHQHYNHKCDVFSYGILLWELISGGDIPYPGYTPLQAARGLRPTIPPSCHPVMAQVMQYCWQSDPNVRPEFEQIVELLKHTEASGAGGGGNGGGSEKQGFFGRLRSGLGTRSAKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMC2</accession>
    <name>C1MMC2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56474</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056905.1">
        <property type="nucleotide sequence ID" value="XM_003056859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMC2"/>
    <dbReference type="GeneID" id="9682344"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56474"/>
    <dbReference type="OMA" id="NARQTHI"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="436"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="516" mass="54510" checksum="ACC8B3B93F53CFB3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MML5</accession>
    <name>C1MML5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_56576</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056949.1">
        <property type="nucleotide sequence ID" value="XM_003056903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MML5"/>
    <dbReference type="STRING" id="564608.C1MML5"/>
    <dbReference type="GeneID" id="9682866"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56576"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="145" mass="15694" checksum="F4FD34187EECAB4A" modified="2009-05-26" version="1">MKTPVDRARLVPAHADEVKTRQLKVHVLIHKHARRRSKLRGAELASRRGSVGGDALRASVCFQRGLDLYEGAGVKRDAAAAFACWREAASRGDVDAMYNVGVMYNDGDGVERCVAKALTWFGEAAKRGDAEAAAWCARLRAPSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMS5</accession>
    <name>C1MMS5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex non-core subunit NAF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_56638</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056980.1">
        <property type="nucleotide sequence ID" value="XM_003056934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMS5"/>
    <dbReference type="STRING" id="564608.C1MMS5"/>
    <dbReference type="GeneID" id="9682895"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56638"/>
    <dbReference type="eggNOG" id="KOG2236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DDACHAE"/>
    <dbReference type="OrthoDB" id="21550at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000493">
        <property type="term" value="P:box H/ACA snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040309">
        <property type="entry name" value="Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633">
        <property type="entry name" value="H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633:SF1">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="30"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="280"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="344"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="356"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="408"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="490" mass="50501" checksum="E4BC43301DB4F36A" modified="2009-05-26" version="1">MAQDAVTVVPAGEGDLAVAAAFATGADSTKILPPARADSTDGEGDDDDDDDDDDDATRVKAHDANAANAAENPEFEFSDGDDETTTTTTGGRARRRAIPDVIRDGDDSSEWESSDDESVEELDLENMPKWLQDIKDGVDTRGGGGGGGGGGGDDFDGDDDGDSVPPRTLNEVAPDATPAPAPPPPIDPDEAVAHVGDVVSVVGDTIVVQSLPGIEYLDEESVLCLSDRVALGAVEEVFGPVAAPLYALRVPRRRRETRAENGSGSGSGCGNETAAAAAAAAKAKESGATEDKDDGATDAKDGGDDEAHKTTNTNTTAAIEVKVGARVYVVEGRRRRLTTAGLYRKGYDNSGKNDEEISDDDEFSDDEKEAEAKKKRRQRKRGIDGEERPADRRVADGGLAAAAAAAGAGAGLGGGRGGQRGGGPPPRARAFQPNAPPAMQMAHMSGIGAGGNVGAGHPAHTTRGPPPPMAPVRSMHWSPYDPVREVNAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMS9</accession>
    <name>C1MMS9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56643</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057457.1">
        <property type="nucleotide sequence ID" value="XM_003057411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMS9"/>
    <dbReference type="GeneID" id="9682422"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56643"/>
    <dbReference type="OMA" id="KRYPEDD"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="232" mass="24555" checksum="9FD7E00A87ED43DA" modified="2009-05-26" version="1">MMSFLRRERRRPTPSIPPPRPQPFRDDDDCEQRLAKTPRTERKRYPEDDDDENDGASSRYPLRSRTPLTLMKNMSKASLYVPPPARTVAEMKASNAKSSTTATTTAAAAGKGGSIPAPRRLVAFADCDPPPKLKTAPPAAEKKPPAPAPAPLAAICRTAAASWKRKANGERGASGYDASAERGRGGISTYTSSSSSSAAAAAAAASSRRGSRSRGGRGRSVRVVVVPPANAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMX2</accession>
    <name>C1MMX2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56695</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057483.1">
        <property type="nucleotide sequence ID" value="XM_003057437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMX2"/>
    <dbReference type="GeneID" id="9682439"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56695"/>
    <dbReference type="OMA" id="WLVWPDV"/>
    <dbReference type="OrthoDB" id="10661365at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="496" mass="52101" checksum="66E36BAF9C6B60F8" modified="2009-05-26" version="1">MASASPSPSPSPSPSPSPSPSPSRVRPLKWLVTDLLAAHVDELIELAGESLLQLPSDVRCALRAVARRRGCLDDRALLALVDGHDGAPFLDVAGCVGVTDDGIDALARRGALAAVVAADVTGCGGISARGIATLCAAAPMMHTLRCGGDDACDDAMRRAIDPGGGGRGKLTRGGRRERGVGGILPRFDDARHHHHVESWEDRAAAASPPPAASSSATDTLTTARASSLQWLVWPDVDVAHRELIRAECPRMRIVAPSKEAYLAAAAVATSPRFRAVDGEGWVAVGKAASAPVDGGGVSCPCPRPRPRPRPKPRGIGFGRGENNDGFVVVASASPPPPPPRPPPWPISPPPPPGAPPPREADPTTPLDAPALACLDASARSGWRGEAAASTEAMMFFSGGMKDEDGGAAPSKRGLGLGAAALRWRLGFAEDADGVSVAERFKRACEEVDAERKLKREKNRRKGRNRTLNKLGKSSYERAMFDALDDRSPFDPRRRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MND0</accession>
    <name>C1MND0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_56872</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057559.1">
        <property type="nucleotide sequence ID" value="XM_003057513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MND0"/>
    <dbReference type="STRING" id="564608.C1MND0"/>
    <dbReference type="GeneID" id="9682998"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56872"/>
    <dbReference type="eggNOG" id="ENOG502SCIV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="534422at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="37"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="333"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="467"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="333"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="495" mass="53337" checksum="5DB5B0D3E9B188E6" modified="2009-05-26" version="1">MSGDGGGGPAPAPGAGDAPPSVDELPRGFVPKPPKKCLNCAASYESLRRCSRCKAVYFCNATCQREVWKEHLKTCVPAPLSAKAEAEKAEIEKLRAREEAAKTRPPPRPPPPQTTTPQSKPEQVKADELVRVRTAILPEVDRLMKLGEYEDAIEHLDDGVAVASAHDERELLDSLSCLVARCYLRLNKPKDARDGLNPALMQARREGGKNAMKPHSIAAEICKAMGDETQMRVELKALMEAAQDAGVDAREQGAALYLAGCLLDDVGDDAAATPLLTSAADAAEKTRDHGMRAGAMSRIGRAMMRARKPRGAIDAWTDELRALDEGERANAEDALRRVDVSEEKQKDKDKEGGDRGEGGEGEKQDNDDDAKTPSTPPLPYRPLGDARARRCRAHANLYAARAVTRDRPRADAHLDAALSIANGMGDARDVARELGKLWLQVGHARRLASVGEEGEEKDVAEAYERAAAKAREAGDDETAKEAEEGLAKSAGKKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNE3</accession>
    <name>C1MNE3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_46561</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056636.1">
        <property type="nucleotide sequence ID" value="XM_003056590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNE3"/>
    <dbReference type="STRING" id="564608.C1MNE3"/>
    <dbReference type="GeneID" id="9682529"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46561"/>
    <dbReference type="eggNOG" id="KOG2034">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498989at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007810">
        <property type="entry name" value="Pep3/Vps18_beta-prop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF26">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05131">
        <property type="entry name" value="Pep3_Vps18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pep3/Vps18 beta-propeller" evidence="5">
        <location>
            <begin position="93"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="447"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="730" mass="76637" checksum="4EE8B9E8508B32C7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNN1</accession>
    <name>C1MNN1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_25478</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056676.1">
        <property type="nucleotide sequence ID" value="XM_003056630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNN1"/>
    <dbReference type="STRING" id="564608.C1MNN1"/>
    <dbReference type="GeneID" id="9682577"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25478"/>
    <dbReference type="eggNOG" id="KOG1714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IMGADIC"/>
    <dbReference type="OrthoDB" id="6353017at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000039">
        <property type="entry name" value="Ribosomal_eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021132">
        <property type="entry name" value="Ribosomal_eL18/eL18-A/B/_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17135">
        <property type="entry name" value="Ribosomal_L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01106">
        <property type="entry name" value="RIBOSOMAL_L18E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="2"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="183" mass="20281" checksum="08396C11B84998F1" modified="2009-05-26" version="1">MGIDLEAGGRNKVKHRTAPKSENVYLKLLVKLYRFLARRTDSDFNKTVLKRLFMSKINRPPLSLSKLAKFHKGGVSAIVGTVTDDARMFEVPAMKVCALRFTETARARIIKAGGECMTFDQLALSAPTGDGVTLLRGPKNSREAVKHFGAPGVPGSHAKPYVRHKGRKFEKARGRRKSRGYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNR0</accession>
    <name>C1MNR0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_55996</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056690.1">
        <property type="nucleotide sequence ID" value="XM_003056644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNR0"/>
    <dbReference type="STRING" id="564608.C1MNR0"/>
    <dbReference type="GeneID" id="9682592"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55996"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46065">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46065:SF3">
        <property type="entry name" value="FI20425P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="11">
        <location>
            <begin position="164"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="90"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="437" mass="47009" checksum="9D5E8417E91FBE2F" modified="2009-05-26" version="1">MRVVNVEGVDIGVDPAARRITIPGGDDGHHHPAHPVNAVAFLAAGMWLRHLQRVVRREERAELGEEDARGEDADGLRDLARAVAVANANANANARAPHDAEDDARDDPADAEGVATTATRDALESHPLADPTDDPSRGASTTTTSTTTSTTTTITTTTPDATAPVAGGGRVCRFCFVGDDDDDDDGGGGGGDGDVLVSPCRCTGTQEWVHVGCLRQWQRVSMRSSGAREKRCRVCHATFKLPRPPMREALAQWFSSRATDRLSQYKRVWWQMLSNSVLAQEGTPHLSSANQLLRLVIASELRIWGGREVRGGNRALRTLRRVARDCTNFHSIVLVAWLLSLGALSAGDALNHPGGPLDVIDQELRARQGAGAGRGGRGERGFGWRGKLFGAAKLVVGKPLGFALRLVVPSAGAFMRLAEPVHGVITWVERYPQYRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNY4</accession>
    <name>C1MNY4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_15179</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle pole</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056725.1">
        <property type="nucleotide sequence ID" value="XM_003056679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNY4"/>
    <dbReference type="STRING" id="564608.C1MNY4"/>
    <dbReference type="GeneID" id="9682631"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15179"/>
    <dbReference type="eggNOG" id="KOG0738">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LHAPRYE"/>
    <dbReference type="OrthoDB" id="191529at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19509">
        <property type="entry name" value="RecA-like_VPS4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000434">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A-like 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF78">
        <property type="entry name" value="KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="98"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="353" mass="38661" checksum="C3B15A1799894D0A" modified="2009-05-26" version="1">MGRRGEEGTAEEEGTAEEEEEEEEDWENARRVLKPPPTFGGSSELRDLARVITRDIHTANPNVRWRDVVGLDDAKRLLKEAVVMPVKYPQFFHGLLTPWRGVLLYGPPGTGKTMLAKAVATECGTTFFNIAASSIVSKWRGDSEKLVRVLFELARHHAPSTVFMDELDAVMSARDGGGGASGGGDHEASRRLKTELLIQMDGLAKSDELVFVLAATNLPWDLDPAMLRRLEKRVMVSLPSRDARRAMASSLLSAHAVDDLDGALDRIAAATEGHSGSDVHSLCKECAMRPLRRLMAKLDDDLEPRDGMEEEVAAMGAITEEDVSGALREAKPSHAAAHSRRYETWTESHGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNY5</accession>
    <name>C1MNY5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56077</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057192.1">
        <property type="nucleotide sequence ID" value="XM_003057146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNY5"/>
    <dbReference type="GeneID" id="9682075"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56077"/>
    <dbReference type="OMA" id="KGYWGGA"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="123" mass="12905" checksum="89A70B3922480068" modified="2009-05-26" version="1">MGKSRRRKDKKNGVDTTMAVAAPAGDAGWVVGDGVTAMLEGEDGAAAVAPTTPTVNANGGKMTAGIRVGKKTPTVLRGITKRKKKMVAKGIAHAERKEGTLKKKTFKRGLRQEAKGYWGGANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPP3</accession>
    <name>C1MPP3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56983</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057988.1">
        <property type="nucleotide sequence ID" value="XM_003057942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPP3"/>
    <dbReference type="GeneID" id="9683426"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56983"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912055" evidence="3">
        <location>
            <begin position="27"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="169" mass="17781" checksum="6E1FCC3F27F25543" modified="2009-05-26" version="1">MPTPRAWTLLALVLALAFHADGGADALPIADHVSSIVTRAKEARAAAAPAVRAARDRVVARVANSTVVEAVGDLRAGMASLSVKSAREDEEEEEEDGGSSAEGVTSDGHVISGRAHGVASFLSLAMCVSFSIWVASAFCRVRRREGDVLPTFELTSEGRRALRHPGTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQH0</accession>
    <name>C1MQH0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57288</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057757.1">
        <property type="nucleotide sequence ID" value="XM_003057711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQH0"/>
    <dbReference type="STRING" id="564608.C1MQH0"/>
    <dbReference type="GeneID" id="9683563"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57288"/>
    <dbReference type="eggNOG" id="KOG1828">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ERRDLEW"/>
    <dbReference type="OrthoDB" id="21648at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34057">
        <property type="entry name" value="ELONGATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34057:SF1">
        <property type="entry name" value="ELONGATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="560" mass="56746" checksum="D683768EF510D599" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQY0</accession>
    <name>C1MQY0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57453</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058208.1">
        <property type="nucleotide sequence ID" value="XM_003058162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQY0"/>
    <dbReference type="STRING" id="564608.C1MQY0"/>
    <dbReference type="GeneID" id="9683272"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57453"/>
    <dbReference type="eggNOG" id="KOG2936">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NGWHWEE"/>
    <dbReference type="OrthoDB" id="567237at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009:SF21">
        <property type="entry name" value="ACTIVATOR OF HSP90 ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="2">
        <location>
            <begin position="29"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="166" mass="18690" checksum="2CCF921C58343AC5" modified="2009-05-26" version="1">MAKWGEGDERWIVQEREDGVNVNGWHWQEKNYMGWGRERLSDLLTAVTFDLPNDEGSASVIEISKFEGDAAVSIRKGNKKFAVFDLNITLKWEGTCEGFEGDGIVKGEIKIAEFASTNDEDEYEFKVTASDGDADAKKKMKQKIKSVVAEAFMPHLNTFAKELAEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQY4</accession>
    <name>C1MQY4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57457</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058210.1">
        <property type="nucleotide sequence ID" value="XM_003058164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQY4"/>
    <dbReference type="GeneID" id="9683274"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57457"/>
    <dbReference type="OMA" id="GPYGWFC"/>
    <dbReference type="OrthoDB" id="10376425at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912085" evidence="1">
        <location>
            <begin position="25"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="251" mass="27718" checksum="187C16984A4FC6AF" modified="2009-05-26" version="1">MTRPRASAALTLRIALLLLASGTSRVRDVARRGLDANEPRASWIRPGRGGVVLADAQADDNPLSITTSTTTDGRECSVGPYGWFCDPASVDNDVKYYTAVPFEGQEPFDTPDGLVGAFPDGLPPLCTISCVDDCQPPCPVECVRAKFEARVEALDSGTAGVFINRDTHQFYVNPYNGSDAWPGTRTQPWETLKRAQAQVRFMRVQNTEQPDSVKLLDPVQIWIRSFDHAQTEDYRANGEENSRFMGFTILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRD0</accession>
    <name>C1MRD0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_67648</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058285.1">
        <property type="nucleotide sequence ID" value="XM_003058239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRD0"/>
    <dbReference type="GeneID" id="9683345"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67648"/>
    <dbReference type="eggNOG" id="KOG2933">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FFTNTEY"/>
    <dbReference type="OrthoDB" id="63891at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024395">
        <property type="entry name" value="CLASP_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567">
        <property type="entry name" value="CLASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567:SF87">
        <property type="entry name" value="CRESCERIN-LIKE PROTEIN CHE-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21040">
        <property type="entry name" value="CEP104-like_TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12348">
        <property type="entry name" value="CLASP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="2">
        <location>
            <begin position="2"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="2">
        <location>
            <begin position="289"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="521" mass="53483" checksum="D70C10886B257D01" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRF7</accession>
    <name>C1MRF7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_57637</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VPRBP/DCAF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057919.1">
        <property type="nucleotide sequence ID" value="XM_003057873.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MRF7"/>
    <dbReference type="GeneID" id="9683738"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57637"/>
    <dbReference type="eggNOG" id="KOG1832">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RAQHRQC"/>
    <dbReference type="OrthoDB" id="27563at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033270">
        <property type="entry name" value="VPRBP/DCAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13129:SF4">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13129">
        <property type="entry name" value="VPRBP PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="593"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="771"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="895"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1023"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1107"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1689"/>
            <end position="1721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1769"/>
            <end position="1897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="596"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="798"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1023"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1115"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1158"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1174"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1689"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1699"/>
            <end position="1721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1776"/>
            <end position="1823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1830"/>
            <end position="1857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1867"/>
            <end position="1887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1888"/>
            <end position="1897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1897" mass="197270" checksum="151BF0C4D4EA5412" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRK0</accession>
    <name>C1MRK0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrate high-affinity transporter accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NAR2.1</name>
        <name evidence="2" type="ORF">MICPUCDRAFT_70904</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058320.1">
        <property type="nucleotide sequence ID" value="XM_003058274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRK0"/>
    <dbReference type="STRING" id="564608.C1MRK0"/>
    <dbReference type="GeneID" id="9683380"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70904"/>
    <dbReference type="OMA" id="VGTMSFF"/>
    <dbReference type="OrthoDB" id="510280at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010167">
        <property type="term" value="P:response to nitrate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016605">
        <property type="entry name" value="Transptr_NO3_Nar2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34806:SF1">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 3.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34806">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16974">
        <property type="entry name" value="NAR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912092" evidence="1">
        <location>
            <begin position="22"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="213" mass="22469" checksum="0812E9B47CAA2204" modified="2009-05-26" version="1">MNKFVLAIAALLAFAVNSASAATKYSALTKLSTVTLDVGGAGTGSTDCGATQLAGAHSDTITVAWTGFTSNSEASLTIKMCYTDDMIVNRPWRKYVDAVDKNKQCWQIPEMTKTLHSGIATADGSKTITIPTNTPASTYYFQVIGVDASGGYVSYGESSTNSCKLTTKSYDNTPATLVGTHATLTVISIIALGVTYAVDLRKQQATYAPYVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSE2</accession>
    <name>C1MSE2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_44364</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058664.1">
        <property type="nucleotide sequence ID" value="XM_003058618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSE2"/>
    <dbReference type="STRING" id="564608.C1MSE2"/>
    <dbReference type="GeneID" id="9684477"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44364"/>
    <dbReference type="eggNOG" id="KOG0880">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CVIKDSG"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000001">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006522828" description="Peptidyl-prolyl cis-trans isomerase" evidence="5">
        <location>
            <begin position="37"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="50"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="217" mass="23145" checksum="BFA22C4CD6E61BD3" modified="2009-05-26" version="1">MAMLLSTFSRPSSGRARVFVALLVALLLLGVNGADAKKKKKGPKITHTVFFDVAIAGEPAGRIEMGLYGKTTPKTAENFRALATGEKGFGFKGSSFHRVIKDFMIQGGDFTNGDGTGGKSIYGETFPDENFKLKHTGPGTLSMANAGPDTNGSQFFICTVKTSWLDGRHVVFGKVTNGMDVVKAIEALDGTPPKQEVTIVDAGEIPMDEPKQEEIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSS0</accession>
    <name>C1MSS0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_39637</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058726.1">
        <property type="nucleotide sequence ID" value="XM_003058680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSS0"/>
    <dbReference type="GeneID" id="9683797"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39637"/>
    <dbReference type="OMA" id="TLWIGRA"/>
    <dbReference type="OrthoDB" id="498948at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="427"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="787"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="803" mass="83107" checksum="714F459BF06DA348" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU29</accession>
    <name>C1MU29_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_58648</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059122.1">
        <property type="nucleotide sequence ID" value="XM_003059076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU29"/>
    <dbReference type="STRING" id="564608.C1MU29"/>
    <dbReference type="GeneID" id="9684866"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58648"/>
    <dbReference type="OMA" id="FFECERV"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="SAP" evidence="5">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="331"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="76"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="292"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="473"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="545" mass="56185" checksum="A7B87C6E1A03B486" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU46</accession>
    <name>C1MU46_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heme-binding peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_58664</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059131.1">
        <property type="nucleotide sequence ID" value="XM_003059085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU46"/>
    <dbReference type="GeneID" id="9684874"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58664"/>
    <dbReference type="OMA" id="SILCEWK"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00314">
        <property type="entry name" value="plant_peroxidase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF8">
        <property type="entry name" value="L-ASCORBATE PEROXIDASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912130" evidence="8">
        <location>
            <begin position="28"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="489"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="56"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="340"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="811" mass="86708" checksum="960BA3CEF616F694" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUJ3</accession>
    <name>C1MUJ3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_17886</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059208.1">
        <property type="nucleotide sequence ID" value="XM_003059162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUJ3"/>
    <dbReference type="STRING" id="564608.C1MUJ3"/>
    <dbReference type="GeneID" id="9684944"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17886"/>
    <dbReference type="eggNOG" id="ENOG502QR1Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WFWLTIL"/>
    <dbReference type="OrthoDB" id="447756at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021919">
        <property type="entry name" value="CCB1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35302">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35302:SF1">
        <property type="entry name" value="PROTEIN COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12046">
        <property type="entry name" value="CCB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="210" mass="22806" checksum="11F13F61C2E28B76" modified="2009-05-26" version="1">MTLFSSPLATAAPLFALAEGLRDDIKPSYFATLGLFVLSAPGLWSLVKRSAKSKVDRKTFEVAGPSATPSMPLDELAREIAAFFRRNNYVVADAGEVITFEGNIAPEKGTAAYITFCVAVGLLCIALVCSIALPGGNLWYSIALISPLSGTYYMDNAGRKEKVKVKMVTADDDMTTDIIVEGDVEEIERMRRDLNLVEKGKVYVKGILEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV26</accession>
    <name>C1MV26_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_69733</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059294.1">
        <property type="nucleotide sequence ID" value="XM_003059248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV26"/>
    <dbReference type="STRING" id="564608.C1MV26"/>
    <dbReference type="GeneID" id="9685041"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69733"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1577640at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="157"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="232"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="361" mass="36010" checksum="0FD193410DE4D3EC" modified="2009-05-26" version="1">MTLKPRDFTPKARARRELTRASREVHVAAARALSEAAMRGAIERAAAAAAAARATDPKATFDVDAAARVAVLDDDDDYDDDDGDGTMTPLARAASRPTRAGAACARALVDAGASVTVACGASGCAPLHRAAACNADRVAEVLLARVDGVALDARDAGGLTPLHVAIVNGATETAIALIRNGASVDVTSGGPGAGGGNWDALAHAARVGDEAVVAAVLDANRRAASNSTETVTTTTPLHIAARRGHAAIVQTLLDAGADAGAVDAFGSTAAAAAAASGHHAIATLLSARGGDERANANANADADADADADAGGERRDEPRSALEWAAYEGGEANVRAAIAAADEKVRCVLCHTGSHTTASAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV57</accession>
    <name>C1MV57_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59061</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059608.1">
        <property type="nucleotide sequence ID" value="XM_003059562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV57"/>
    <dbReference type="STRING" id="564608.C1MV57"/>
    <dbReference type="GeneID" id="9684758"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59061"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="639" mass="66802" checksum="AC3299C947D77CF5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV88</accession>
    <name>C1MV88_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59096</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059331.1">
        <property type="nucleotide sequence ID" value="XM_003059285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV88"/>
    <dbReference type="GeneID" id="9684771"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59096"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="139" mass="14257" checksum="7C9014BCFA90E0FA" modified="2009-05-26" version="1">MEKDRAEALVAVATTLLTDAVRNVNDHNDGGLFSVFRGNRGQGLFGGVVVGADGKSKWVTKQIVRAGANRDARPKGITEEIAFEGDKGTDAVAVQSPYRQLSRGGLGRTKKGGGGGGGGGASFAKKPPSPVEEGSEESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVQ9</accession>
    <name>C1MVQ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_34256</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059793.1">
        <property type="nucleotide sequence ID" value="XM_003059747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVQ9"/>
    <dbReference type="STRING" id="564608.C1MVQ9"/>
    <dbReference type="GeneID" id="9685232"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34256"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ATWCQRD"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000669">
        <property type="entry name" value="Cyanobacterial-type MPBQ/MSBQ methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="PiNMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF11">
        <property type="entry name" value="GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="8">
        <location>
            <begin position="219"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="17"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif I" evidence="6">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif II" evidence="6">
        <location>
            <begin position="283"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="6">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="449" mass="48179" checksum="CBE3CCB9D4146EA8" modified="2009-05-26" version="1">MHAHAVNALALSSSRAALDGAARPRGRAVAPSTRARGRAARCPTIASASASSAHRDAATSDRSATTTLSVADLARPALPSHGANEIATVAGRAAAAPPPPPAPAFPHNVPTPALVAAGALALALGAKAILDKPSRAYVQGPGGDSIGTVGEEYDAWTEEGILEHYWGEHIHLGYYTDEDMAKGAGTLLGCRVKDFVEAKFDFVDKMLEWSGCPPNPAMVLDVGCGIGGTSRHLAKALGPKSKVQGITLSPNQVQRATELAATQGVDNASFRVMNALEMEFPDDTFDLVWACESGEHMPDKKKYVEEMIRVLKPGGTIVIATWCQRETPPAFTDEEKANLKFLYEEWAHPYFVSIEEYVRLMEGTGAMATVGSANWVKETIRSWRHSIWVGVWDPWPVVFAGPRIWYKTIREIVTLERMHRAFDCDLMTYGMMKGTKAAAAAAAAAAAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW65</accession>
    <name>C1MW65_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_18271</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060163.1">
        <property type="nucleotide sequence ID" value="XM_003060117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW65"/>
    <dbReference type="STRING" id="564608.C1MW65"/>
    <dbReference type="GeneID" id="9685308"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18271"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WGVSNEN"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF17">
        <property type="entry name" value="ALDO KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="413" mass="45854" checksum="5250EA6D606DA003" modified="2009-05-26" version="1">MTTDAKTVPRRAELRKVKFGNTDMMVTEVCGGTMTWGSFNDEEEDAHAQLDKLWELGVNFLDTAELYPVGWNYGALTEKWMGNWLGASSSARTRAKLYIATKVNPSTVGAEHPTRSGAHGYDEEIVLWSCQKSIERLKCGYVDLYQIHWPSRDCPLMSTPTFAPDGKNRMMPFFDRGTQEDFDRTVRSIKTLFERGLIKHWGVSNENAYGITMLCNACVKLDCPLPVSCQNDFSLLNQTYECDTYEAAYRFGVVGLPYGALAGGTLTGKYFEKTKPEYAAKDATERPLEKCRHRVMADFQPRYGSKAAMAATREIVDIAEAWGVTPTELSLAWAIGRPCNASVIIGTTTTRQVEECVGAALLDLPDALVKELDAVHEKYRNPCMYYADKEVWNAHGGAGRAAAVPEGAAVPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW83</accession>
    <name>C1MW83_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65583</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059878.1">
        <property type="nucleotide sequence ID" value="XM_003059832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW83"/>
    <dbReference type="GeneID" id="9685610"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65583"/>
    <dbReference type="OrthoDB" id="1932153at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="236" mass="25773" checksum="135451735BEC943F" modified="2009-05-26" version="1">MAASNAESDNAPVTTSAPPPPPRVQAPARKPPPSTGPSASLKNEGKGKGIAGKIFGFVLGTSSTTVRLDMQRPAFTRDRARQTNHNGWGDGPADVRGEKSDGPVRHNFNVEQTRLKVTQKWEAGAFTRLGDGGAKKSRVDLGVGLDVSLMEAEVLPECRVRVRLGNDKYSPNIYLRALPRQEIVARGRVPLLNTDLSLGVRVEVRLVPIRPRSRCARRSLRTFTVVTLHPRFPFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWA8</accession>
    <name>C1MWA8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_18620</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DPH4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059892.1">
        <property type="nucleotide sequence ID" value="XM_003059846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWA8"/>
    <dbReference type="STRING" id="564608.C1MWA8"/>
    <dbReference type="GeneID" id="9685621"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18620"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LEDMTWE"/>
    <dbReference type="OrthoDB" id="442087at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45255">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45255:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="6"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="DPH-type MB" evidence="6">
        <location>
            <begin position="88"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="181" mass="19104" checksum="B39FC7A738F521DE" modified="2009-05-26" version="1">MSSSRTHYEVLGVDARDASTEDIKRAYKAAALASHPDKRASRVDGAAGDNSEFLKVQAAWEILKESASRAAYDARLLETARRDADVVVSDEFDIDDMDAEGSSPTKFTRRCRCGDAYEVWSDELLASFDAIDVPCASCSLHVRVRLTGGAAAAKFDAFAMATAAATAAAAAAAGTKDDAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWJ9</accession>
    <name>C1MWJ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59796</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060231.1">
        <property type="nucleotide sequence ID" value="XM_003060185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWJ9"/>
    <dbReference type="GeneID" id="9685669"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59796"/>
    <dbReference type="OMA" id="REPAPWA"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="365" mass="39933" checksum="7D9C6055A3DAE8A4" modified="2009-05-26" version="1">MTQLANLAPGHRETRPHVLAEAQVRRDANDRARVAFNARAEKAKERTTAEDAKCDDGRDADAARRPRRQRASTSNPNDAGALPGVRETTDDDVAGAAHLAVASTLAAKGRVAEAECVLFNVLRARPNDAGARWLLRQIREPSGAVPGRGPPKTKATPKPPQPEPEVPLEELFARLKGAPEPPGGRRVAELMKRLDREMGERETPMLVGVGPAPRMDLGPVRGRPAAGASVVTLSDLDDELAKKKARLAEERRRDMEFDARVAADERAAIAREDAAAADAKRRATREQKFGLDAQQRVDRERRDQLWAEEKRKGLEATRGGRESSEKTEVGRGSVAVIGGEEMAPRGKKTREPPKRRALAPFAFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWQ4</accession>
    <name>C1MWQ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59211</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059668.1">
        <property type="nucleotide sequence ID" value="XM_003059622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWQ4"/>
    <dbReference type="GeneID" id="9685124"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59211"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="109" mass="11245" checksum="019AA80D910D0AAE" modified="2009-05-26" version="1">MGLGREIRPGSRGLEWAASHGVPRVAFVGDCALSVLCFASACAVAGLRSGVGELGRVLDISRRSPINYCDNAGGRWCAQMDAGAVFAFLTAISVVPSAVANSMNSCGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX40</accession>
    <name>C1MX40_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60020</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060332.1">
        <property type="nucleotide sequence ID" value="XM_003060286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX40"/>
    <dbReference type="GeneID" id="9685770"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60020"/>
    <dbReference type="eggNOG" id="ENOG502SUGV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CRHYVND"/>
    <dbReference type="OrthoDB" id="513772at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36342">
        <property type="entry name" value="PTB DOMAIN ENGULFMENT ADAPTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36342:SF1">
        <property type="entry name" value="PTB DOMAIN ENGULFMENT ADAPTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="380" mass="39383" checksum="87C096B150E606F2" modified="2009-05-26" version="1">MAMGSRAGTVLFPPALQGVGEATTAEEELVEPELYVTTRSFRADRSFLGRLPPPARDALSTGGVCHFLCVYKSERGEIFQFDFGPFGGDVHSAMLSDTGSSSSSSSSSTPGHVREKKLDALPANGTYLVGKTSMTLDDVRAFNKKRDTIYNVNKNDCRHYVNDLCELGCGFTNACSKYVKGEVFGRSMFSRAAEERAEERRRRATELAVLVPIMAVTDLENAPLWERLQHGSTAALIIGVGVRAVPPALVAVASARAAAAGGASAKVAASAGMSLGAAAAGLGGAIEAMGAGGILARAAAASKPLVAPVARRLITTAAGVIGGASEDIQRTVRPGYDRAVRAMSSIRGNWGGSGAQGRRATPALGWAGQRNLQAAGGGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX57</accession>
    <name>C1MX57_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60036</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060338.1">
        <property type="nucleotide sequence ID" value="XM_003060292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX57"/>
    <dbReference type="GeneID" id="9685776"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60036"/>
    <dbReference type="OMA" id="SEDNAMP"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="415"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="480"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="621"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="695"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="142"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="238"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="282"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="522"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="551"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="572"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="627"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="700"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="726"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="751"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="768" mass="83373" checksum="814C133D8AE449CD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXB7</accession>
    <name>C1MXB7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_60097</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060665.1">
        <property type="nucleotide sequence ID" value="XM_003060619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXB7"/>
    <dbReference type="STRING" id="564608.C1MXB7"/>
    <dbReference type="GeneID" id="9686102"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60097"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CVICACA"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="205"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="254"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="445" mass="47396" checksum="AF03AC4DA5F38E50" modified="2009-05-26" version="1">MEEEAADLRAEVRRAREAREARERVRSALGTAIAGVGLALGGGERADADGRGAGGRVGAAAGIASSPSDDDAIERAWNAPPRRPDDDSDLLSDAALRRIVDRIYREQVAATRLARVAGEGGEEDEGAERPTRRSRAAARGDERYRRARRPLSAEEFDALPSLRYGEEEDAAKEEEEEEEEEADAATTEPTEPAVASPPPPPPEDCVICACAFAPADALKRLPCGHSGFHVDCIRAWLSRSPTCPLCRCACRAAPPPRTRDDDDDDGDDDDDDDDDDGPPSLTDASSLADDDFVSTEHLAELQSMHAEESAWLDRLESQPRARLYDRLYDLPAAVAAAAEDGTPTDADAAAGAEDAARTVAARTEAARARGGAGDASLDAGAAARAREEGRGGRRRGERAPPPGPPGRRVDRVELPLTTAALERDRRSRASAADALERWRGSEGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXP4</accession>
    <name>C1MXP4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_34682</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ISY1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060726.1">
        <property type="nucleotide sequence ID" value="XM_003060680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXP4"/>
    <dbReference type="STRING" id="564608.C1MXP4"/>
    <dbReference type="GeneID" id="9685872"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34682"/>
    <dbReference type="eggNOG" id="KOG3068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YHWERRI"/>
    <dbReference type="OrthoDB" id="1739576at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000350">
        <property type="term" value="P:generation of catalytic spliceosome for second transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.660:FF:000001">
        <property type="entry name" value="pre-mRNA-splicing factor ISY1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009360">
        <property type="entry name" value="Isy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037200">
        <property type="entry name" value="Isy1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13021">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ISY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06246">
        <property type="entry name" value="Isy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140102">
        <property type="entry name" value="ISY1 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="269" mass="30652" checksum="676CF6AFC6B8F606" modified="2009-05-26" version="1">MARNEEKANNMFNRWTAGKQAALRGEKARRPYLASECKDLNSADKWRQDILREIGKKVMDIQNAGLGEHRIRDLNDEINKLIREKHHWEKRILQLGGPNYISQGRRIADEEKGEVVGRPGGYQYFGAAKNLPGVKELFEKPKPRTVRRSRAQMLKCIDLDYYGMRDEEDGTLVKLEAEAEEKLRAKKIAEWEAKQREIEAITGKRKHDGDGDDGVAFGSEFVAHVPLPDNKDIEALVLAKKKKDLLAKYASEELQAEEAEAKSMLNKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY51</accession>
    <name>C1MY51_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Centriolar satellite-associated tubulin polyglutamylase complex regulator 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_60403</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Regulator of the tubulin polyglutamylase complex (TPGC) that controls cytoskeletal organization, nuclear shape, and cilium disassembly by balancing microtubule and actin assembly. Regulates the assembly and stability of the TPGC and thereby modulates polyglutamylation of the microtubule, which antagonizes MAP4 binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriolar satellite</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CSTPP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060810.1">
        <property type="nucleotide sequence ID" value="XM_003060764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY51"/>
    <dbReference type="GeneID" id="9685945"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60403"/>
    <dbReference type="OrthoDB" id="64214at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22959">
        <property type="entry name" value="DD_C11orf49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038968">
        <property type="entry name" value="CSTPP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057632">
        <property type="entry name" value="TPGS1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34252:SF1">
        <property type="entry name" value="CENTRIOLAR SATELLITE-ASSOCIATED TUBULIN POLYGLUTAMYLASE COMPLEX REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34252">
        <property type="entry name" value="UPF0705 PROTEIN C11ORF49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24480">
        <property type="entry name" value="TPGS1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin polyglutamylase complex subunit 1-like C-terminal" evidence="10">
        <location>
            <begin position="76"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="187"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH55579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="288" mass="30577" checksum="AB69C6892B513F58" modified="2009-05-26" version="1">MDAATRRAAAADATAASRAHPHPAPPIALDVAAFDRSSLTVYLNDALTLVFENRPEDPIAFCADYLRRVLSGAGPVPRAYQFLTLCPHHRTAFIDNAVVAFGVLEKERGGVSAGDAKAVMQMLCADFPREVAVAVLRALGRGDDDDAEDVDFFEFLGGVRACLAFEEALGEVERAFAMYGAADGDDAAGGGDGGENENENENVVDARDDSRTVPKSTLRDVLRRVGEDVGKRGDKRWDDFRALSTRVVDAIPGTRVTFSRFATAVFRAMAPSPSPASGGGGGVWDALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY52</accession>
    <name>C1MY52_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60404</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060507.1">
        <property type="nucleotide sequence ID" value="XM_003060461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY52"/>
    <dbReference type="GeneID" id="9686248"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60404"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="101" mass="10506" checksum="89B1320C0B6C365C" modified="2009-05-26" version="1">MEGGCAASDAGGLSPRAGSRARSPSTPTTSPPPPLERPSPSSAGYGYVVGPNAIIHTPGPHDRVQAKRYALSRRWLLVDRGGAVSLLEASKAEMQKEARSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY76</accession>
    <name>C1MY76_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60431</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060519.1">
        <property type="nucleotide sequence ID" value="XM_003060473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY76"/>
    <dbReference type="GeneID" id="9686260"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60431"/>
    <dbReference type="OMA" id="GVREDEW"/>
    <dbReference type="OrthoDB" id="498359at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="313" mass="32298" checksum="EB2508CA135F993B" modified="2009-05-26" version="1">MTTTCAASRALTRAVSRRSRPWRDVAASASATSAPPPRDRDASSSSSSSSSSSSSRRSILLGTVVGAATATATGVSLASPPRVLAAALGSVRPAAEAVGGPLLPLADYVAALDAVAVELAAVASELRDALGDATSSSASASDDGDFAYDDPELAIAAPLASSTRAALKSRLHANALGAFWVTARGLDRYLSSERSPFARDREDLWKLLPEKTGPLGRALQPDFNNPDDPLCLVYSCVNDPRAPPSIDVLYALKLLDEGLATKGVTARGLLGNATDAAEKLETYAALVKANADADLIDTEWVNPAPKGWGRIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYD9</accession>
    <name>C1MYD9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59877</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060557.1">
        <property type="nucleotide sequence ID" value="XM_003060511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYD9"/>
    <dbReference type="GeneID" id="9685702"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59877"/>
    <dbReference type="eggNOG" id="ENOG502QU5X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="421671at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF2">
        <property type="entry name" value="LYSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="683" mass="72873" checksum="07D4C333060C0730" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYE4</accession>
    <name>C1MYE4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_11332</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060559.1">
        <property type="nucleotide sequence ID" value="XM_003060513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYE4"/>
    <dbReference type="STRING" id="564608.C1MYE4"/>
    <dbReference type="GeneID" id="9685717"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11332"/>
    <dbReference type="eggNOG" id="KOG1069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CHALMDA"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="6">
        <location>
            <begin position="4"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="137" mass="14131" checksum="5E2E55B492C75115" modified="2009-05-26" version="1" fragment="single">DRSVVYAAVYGPMEIRAGKQDTDKLVIEVVVRPASGAPSSADKEREVTIRRALEHVVKTAAHPRCGIRVVLQTVSSDGGIDAILLNAACAALIDASVDVTGVLCASSLAVLPGVGVVVDPTEDEETAATATATMAYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYG1</accession>
    <name>C1MYG1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_69306</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060522.1">
        <property type="nucleotide sequence ID" value="XM_003060476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYG1"/>
    <dbReference type="STRING" id="564608.C1MYG1"/>
    <dbReference type="GeneID" id="9685960"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69306"/>
    <dbReference type="eggNOG" id="KOG4372">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VEHQAEY"/>
    <dbReference type="OrthoDB" id="273452at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF62">
        <property type="entry name" value="LIPASE ROG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="2">
        <location>
            <begin position="77"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="527" mass="56848" checksum="0D1976C9955BA00F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ19</accession>
    <name>C1MZ19_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_60570</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061139.1">
        <property type="nucleotide sequence ID" value="XM_003061093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ19"/>
    <dbReference type="STRING" id="564608.C1MZ19"/>
    <dbReference type="GeneID" id="9686578"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60570"/>
    <dbReference type="eggNOG" id="KOG2382">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QETWAFN"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="73"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="340" mass="35407" checksum="1D1AA63003450AED" modified="2009-05-26" version="1">MAASGPGRIARALAGATRGRRWRGVAGGILGTPRWLSASSSSSSSSSSPSPLAYEMIEPPAGTPNASDAPIALVLHGLMGAGRNWRTFTRALSSSLAERRAPFRFALVDHVWHGKTHADLALRSLRNPDPDRDGVDAVDVAASAVAAVAGHILRTHGRSGSEPVAAVLGHSLGGKVALRHVARAAAAAAAASRGGGATAHANATDAPPHQTWSLDSVPTYLPPDADPHSVQKVIETVAALPREFAAREDLEPALRSSGVAFPPDLVSWLGSNLVPIDPSAGAMSKLTWTFDVKGAAALYAAYKVRRGGGRERRNFGFFGFVISFRSTSKTRASSPSLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ25</accession>
    <name>C1MZ25_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_28211</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060884.1">
        <property type="nucleotide sequence ID" value="XM_003060838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ25"/>
    <dbReference type="STRING" id="564608.C1MZ25"/>
    <dbReference type="GeneID" id="9686323"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_28211"/>
    <dbReference type="eggNOG" id="KOG3080">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="443772at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008610">
        <property type="entry name" value="Ebp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028">
        <property type="entry name" value="RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028:SF0">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EBP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05890">
        <property type="entry name" value="Ebp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="156"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="420" mass="48282" checksum="DE0591C95A734376" modified="2009-05-26" version="1">MEMDADADAGGGGDGDDDDALEDEDDELEAEMAALESSRRERGYKKLENRAFVNNKEGLRASLDDFQWTKKAKWIDHMVVAGTKTAETLADVNDDLARETHFYEHALRSAEVAIKNLKEIGVAVKRPDDFYAEMVKSDEHMKRVRAELIFEQTSQETREERRKAREQKRYGKQVQAEKIKERTLKKKESIKNLDKWRKQRKQNGFADDGKAPDGFEDAPRQKERGGSRGGGGQHGRSTPESQKKREFKNEKFGFGGRKRVRRRRRRANGRTSAVFFSFRFVTFATFPARIDSKLETRNSIDHRRAQGVLPASLEAWRKGHLLLYGVYPALKRLKVPPAVVGSLGPWRAFARAHIERASRHAPRIFHCLGERRRRHYASGQTMLVLFDPTRFRRRLLETRNARAALRPDVLSPSPSPSLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ26</accession>
    <name>C1MZ26_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_11572</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061141.1">
        <property type="nucleotide sequence ID" value="XM_003061095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ26"/>
    <dbReference type="STRING" id="564608.C1MZ26"/>
    <dbReference type="GeneID" id="9686324"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11572"/>
    <dbReference type="eggNOG" id="ENOG502RY7G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MAIAGQC"/>
    <dbReference type="OrthoDB" id="410458at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007263">
        <property type="entry name" value="DCC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052927">
        <property type="entry name" value="DCC_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33639:SF2">
        <property type="entry name" value="DUF393 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33639">
        <property type="entry name" value="THIOL-DISULFIDE OXIDOREDUCTASE DCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04134">
        <property type="entry name" value="DCC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="123" mass="13401" checksum="820BBF0150EE5E77" modified="2009-05-26" version="1" fragment="single">RPVILFDGVCNLCNGGVNLALDLDPPGELRFAALQSSAGRALLRRSGRDASDISSIVLVERDRSYVKSDAVLRIATYLKRMPLLPIAGVVGPLVPGFLRDAVYDLVANNRYELLGMKDECRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZB7</accession>
    <name>C1MZB7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_41274</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060930.1">
        <property type="nucleotide sequence ID" value="XM_003060884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZB7"/>
    <dbReference type="STRING" id="564608.C1MZB7"/>
    <dbReference type="GeneID" id="9686369"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41274"/>
    <dbReference type="eggNOG" id="KOG3078">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FFPIYGA"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053021">
        <property type="entry name" value="Chloroplast_ADK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35509:SF6">
        <property type="entry name" value="ADENYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35509">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (DUF1995)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1995" evidence="2">
        <location>
            <begin position="100"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="354" mass="39348" checksum="3EFD18C44A5C9329" modified="2009-05-26" version="1">MTSTAFAPSLALRARARPPRASRASSSPIRAFWSGFGGGEKDADAKGKPSSSTRKAPSGRAPGKAKPEDDVNMPTEEDLARKADIPIMLNNTPHPREVRRWFYDDCVTSVTRAVTGEEPMTRVKAKVEFPELNVNGDVYRVGTLLELVRELAMTLAKDGKRVRVCVQGSMGEGVFQGLPLSLSGVARILDMMDWGDADEFISRGAIDGDVPQPEDDFFILIAPQNIVGFAVLPRIIAMEEAAGDRPMIMINPKLDDIQSAGNVMSIRGRGERREYVSTWREVYHFRLLYRKPYFFPIYGAMRYTHDGKWELYKKFGKMESEEYVLKRAYDTGSEGMPGAGEVTKVILAKGERNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZF9</accession>
    <name>C1MZF9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">diaminopimelate epimerase</fullName>
            <ecNumber evidence="3">5.1.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_44639</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S,6S)-2,6-diaminopimelate = meso-2,6-diaminopimelate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="3"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061210.1">
        <property type="nucleotide sequence ID" value="XM_003061164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZF9"/>
    <dbReference type="STRING" id="564608.C1MZF9"/>
    <dbReference type="GeneID" id="9686388"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44639"/>
    <dbReference type="eggNOG" id="ENOG502QQKJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EWEFYNA"/>
    <dbReference type="OrthoDB" id="4768at2759"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.10:FF:000009">
        <property type="entry name" value="Diaminopimelate epimerase chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689:SF0">
        <property type="entry name" value="DIAMINOPIMELATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="DIAMINOPIMELATE EPIMERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="262" mass="27819" checksum="5FC70D6C56846291" modified="2009-05-26" version="1">MCDRNFGIGADGVIVAMPKGSAEYPGRVVEEEDYAMRMFNSDGTEPEMCGNGIRCLANFVAAIDDADPRAYKVGTLAGLIQPECKPDGQVAVDMGVPTLTPADVPTKLAATEDGAAVKSQMTVDGATWLATAVSMGNPHCVTFGREKGDEKGLAVDDMDLAAIGPSFESHETFPARTNTEFVEVVRRDYVKMRVWERGAGATLACGTGACATVVAGVLEGRTDRKCTVELPGGPLEIEWRESDSRVIMTGPAELVFYGEIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZJ1</accession>
    <name>C1MZJ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_60748</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060963.1">
        <property type="nucleotide sequence ID" value="XM_003060917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZJ1"/>
    <dbReference type="STRING" id="564608.C1MZJ1"/>
    <dbReference type="GeneID" id="9686402"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60748"/>
    <dbReference type="eggNOG" id="ENOG502T1HZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THETQHA"/>
    <dbReference type="OrthoDB" id="515366at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF3">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="22"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="185" mass="20972" checksum="7AFCCFB49C5D3D3D" modified="2009-05-26" version="1">MRSSPCPPDPTKPPAPEPDPDAALRLLSWTQDSESAFVRVRVPRGTRAREVLVDATPSSLRVRLDWLPESEAFGGALRETIVASETLWTLETDGTETLVSVVLQKTERDVEQRAWRGLFENDEEKSLQEVLLELTNADERSPAHSALTHETQHAIEEMRERRYQMGCGEFNPDEGFDDFRLVIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZN5</accession>
    <name>C1MZN5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_41349</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060984.1">
        <property type="nucleotide sequence ID" value="XM_003060938.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MZN5"/>
    <dbReference type="GeneID" id="9686690"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41349"/>
    <dbReference type="OMA" id="WRNRSAN"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="353"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="545"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="620"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="743"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="907"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1042"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1384"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1687"/>
            <end position="1711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="472"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="573"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="771"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="928"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1053"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1067"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1100"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1145"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1393"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1691"/>
            <end position="1711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1760" mass="179099" checksum="731798FAE02CFFBF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N098</accession>
    <name>C1N098_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_50938</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061596.1">
        <property type="nucleotide sequence ID" value="XM_003061550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N098"/>
    <dbReference type="GeneID" id="9687035"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50938"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="627"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="677"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="174"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="305"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="556"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="725"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="804"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="128"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="438"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="85"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="567"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="594"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="743"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="808"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="826" mass="89442" checksum="BE7EE6618161A884" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0F8</accession>
    <name>C1N0F8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_20226</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061630.1">
        <property type="nucleotide sequence ID" value="XM_003061584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0F8"/>
    <dbReference type="STRING" id="564608.C1N0F8"/>
    <dbReference type="GeneID" id="9686824"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20226"/>
    <dbReference type="OMA" id="NAHEGDQ"/>
    <dbReference type="OrthoDB" id="66726at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051728">
        <property type="entry name" value="RING-FYVE_E3_ubiquitin-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14879">
        <property type="entry name" value="CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14879:SF5">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="128" mass="13609" checksum="B097F12C56EBB676" modified="2009-05-26" version="1">MLAGVGLLLNRFVRAKIVEWRERRFKRRLAEAEKARREREGGGGADGGATVDDPSSTSSRGGGGGGGGGGGGERAPGETCVVCLYEAASVVYKECGHLVCCELCARRMTRCPLCRRKSAWMKVFRAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N102</accession>
    <name>C1N102_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51211</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061486.1">
        <property type="nucleotide sequence ID" value="XM_003061440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N102"/>
    <dbReference type="GeneID" id="9687162"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51211"/>
    <dbReference type="OrthoDB" id="10610964at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="150" mass="15323" checksum="5488107D25AC5A8A" modified="2009-05-26" version="1">MLFAISTTTSALAAAPTRVPARRRAARVATTTTTRATTTTTTTTTTTSEDNASTASTSRFLAAALAAATIATTACLSAPAPSTANVGYANDCDPICHVLDDGAAKSKAQEEAFKREGPPMGDLMAQLQAQRKAEEAAAAKAAPKKDGTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N130</accession>
    <name>C1N130_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_51241</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061499.1">
        <property type="nucleotide sequence ID" value="XM_003061453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N130"/>
    <dbReference type="GeneID" id="9687177"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51241"/>
    <dbReference type="eggNOG" id="ENOG502SYZC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TEAWCAR"/>
    <dbReference type="OrthoDB" id="495821at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.100">
        <property type="entry name" value="SG protein - dephosphorylation function"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050582">
        <property type="entry name" value="HAD-like_SerB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006385">
        <property type="entry name" value="HAD_hydro_SerB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01490">
        <property type="entry name" value="HAD-SF-IB-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344:SF13">
        <property type="entry name" value="PHOSPHATASE RV3661-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="314" mass="33650" checksum="016056DCC5CD4E77" modified="2009-05-26" version="1">MATTEPVPADAAPATAEETVTAADSALAPAARDVDATSTATATSIGGVDDRRSVPAPSSPSYDDGRGVAFFDLDHTLIDTNSSWLWMKHELNNGKVGAGMLATSVYWFARYAMGFGSGAERAGAEAAELYAGTPEEKLRREVDAFFEKELAHRARPGGKPIMEKHIRAGERCVVCTSSWQHPAASAARLFNCESAVDDVISSVMEVDEAGNLTGKIAKVCYGDGKSVVTEAWCARRGIDLAKCYFYTDSMSDVSLLEKVGHPVAVNPDRRLRAHAKKRGWAVMDWGVAKPKDPMKKPRYSYGCLAFHGAKSGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1N157</accession>
    <name>C1N157_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">GTPase Der</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_44721</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061511.1">
        <property type="nucleotide sequence ID" value="XM_003061465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N157"/>
    <dbReference type="STRING" id="564608.C1N157"/>
    <dbReference type="GeneID" id="9687192"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44721"/>
    <dbReference type="eggNOG" id="KOG1191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CNLPQYV"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01894">
        <property type="entry name" value="EngA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01895">
        <property type="entry name" value="EngA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000004">
        <property type="entry name" value="GTPase Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000040">
        <property type="entry name" value="GTPase Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001185">
        <property type="entry name" value="GTPase Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTPase_Der"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43834">
        <property type="entry name" value="GTPASE DER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43834:SF2">
        <property type="entry name" value="GTPASE DER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="8">
        <location>
            <begin position="4"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="8">
        <location>
            <begin position="200"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="470" mass="50952" checksum="97D9F3C073B840B7" modified="2009-05-26" version="1">MGLPRVAIVGRPNVGKSALFNRLTGTKRAIVYDQPGITRDRMYVRAFWGDSEFMMVDTGGLESLPGNPGAAPSVDAVGGFEILPGMIESQAALAVREAASLVMVVDGQTGLTTADVDIYRWIRKNHADKPLVLAVNKCESTTRGEEQVLDFWSLGGVTPLAVSAISGTGTGDMMDQLCATLPAVNADDEKESGEEVAEPLKVAIVGRPNVGKSSLLNQLSGDARAIVSDHSGTTRDTIDSDVTDADGNKFTLIDTAGIRRRTAVAAGKDKPEELSVGRALQAMRRAEVVVLVIDAEEGPSQQDFVLAERAALTEGCALVLCVNKWDVIDKNSYSMNEYTKSLRSKLRVFEWASVVYVSALTGQRVQKVLAAAVEASTHHRKRLSTATLNAVVQEATLWKSPPSRGGRKGKVYYVTQASTRPPTFVFFCNDPKLFVETYRRYMERSLRENIGFPGTPVRILWRGKGVSGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1I1</accession>
    <name>C1N1I1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_20482</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061825.1">
        <property type="nucleotide sequence ID" value="XM_003061779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1I1"/>
    <dbReference type="STRING" id="564608.C1N1I1"/>
    <dbReference type="GeneID" id="9687264"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20482"/>
    <dbReference type="eggNOG" id="KOG1203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THIICCT"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF50">
        <property type="entry name" value="UPF0659 PROTEIN YMR090W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="5"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="254" mass="26421" checksum="0B77348656233104" modified="2009-05-26" version="1" fragment="single">VLVVGSTGGVGQLVVAKLLESGFRVKALARSEESARALFADAFASDDDAFEVVTGVDLRDAAALERSGACVGVDAIVSCVGTTAFPSARWRDGNGPEATDFVSGAFYTLSPNARRIVLVSSIGVTRTDRMPFLVLNLFGVLKFKAMGEQAVVDSGIPYTILRPGRLTDGPYTSYDVNTVLRATSGTRRAVDLRLGDDLLPEETSRIVVADAAVAALSSAACVGKGYCLGTREGEGPGSDFGKWDALFEGAGGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1N7</accession>
    <name>C1N1N7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51674</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061946.1">
        <property type="nucleotide sequence ID" value="XM_003061900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1N7"/>
    <dbReference type="GeneID" id="9687589"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51674"/>
    <dbReference type="OMA" id="YSAYFAY"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="290"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="340" mass="35631" checksum="41CF1F8F80AD8C25" modified="2009-05-26" version="1">MAMNAMTFRAAVVGSAPSSKLLKSSRVASSAKPTAIVSFFGKKEPAPKKAAVRGLNGPTNRPKVVVAKGKELTGSAAKAAKAKPMFDFSSKPKPVVKAKPKPKPKPVAKKASKPMFGTAKKAKPIAKKASASKPLFSFGGSGAAKKTKPKATMKKSSPASSYTIKKTPFTAKKSATTFKTVQPKKVVAKPAAAKASAPRAASAAKYDRDLVENYGLVPIFAGTFLLTYAVFPAVIENFLEVVGIGYSAYFAYSYYTSPEARANFGQTLDKVDEDFGLDLRSVAAGAGDIANKTSKQLAEQAEKNAEAAAKKKLEDKKAAEKLAADTIKAAGKAAEKEKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1P2</accession>
    <name>C1N1P2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA topoisomerase</fullName>
            <ecNumber evidence="3 7">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_51680</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3 7"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061949.1">
        <property type="nucleotide sequence ID" value="XM_003061903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1P2"/>
    <dbReference type="STRING" id="564608.C1N1P2"/>
    <dbReference type="GeneID" id="9687591"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51680"/>
    <dbReference type="eggNOG" id="KOG1957">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GKWSFAN"/>
    <dbReference type="OrthoDB" id="430051at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.290.10:FF:000001">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056452">
        <property type="entry name" value="Zn_ribbon_TOP3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 3-BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23546">
        <property type="entry name" value="Zn_ribbon_TOP3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="9">
        <location>
            <begin position="3"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IA-type catalytic" evidence="10">
        <location>
            <begin position="168"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="821"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="849"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="862" mass="93662" checksum="1DF26FB13D5115DB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N288</accession>
    <name>C1N288_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51890</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062048.1">
        <property type="nucleotide sequence ID" value="XM_003062002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N288"/>
    <dbReference type="STRING" id="564608.C1N288"/>
    <dbReference type="GeneID" id="9687688"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51890"/>
    <dbReference type="eggNOG" id="ENOG502S7G4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TNCRDAR"/>
    <dbReference type="OrthoDB" id="2148418at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012891">
        <property type="entry name" value="GCK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34357:SF2">
        <property type="entry name" value="F26F24.3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34357">
        <property type="entry name" value="F7A19.14 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07802">
        <property type="entry name" value="GCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01227">
        <property type="entry name" value="GCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GCK" evidence="2">
        <location>
            <begin position="75"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="18838" checksum="5F8475FA1269376C" modified="2009-05-26" version="1">MWWFPTSHAAGAEDASSSRDRAETETASKAATTAAATTAAADEPDRAPDADTKKKEGGDGAKAEEEEEEEEEEEETCGFCKFMKGGSCKATFVKWEKCVDAAKERDDDYVAECAKQTEALRDCMLADPGYYGEMLPDEKEDDDEKGGDGKKKEKEEVTEEPAAKTRAEKALGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2A1</accession>
    <name>C1N2A1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homoserine kinase</fullName>
            <ecNumber evidence="3">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_5371</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-homoserine + ATP = O-phospho-L-homoserine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13986"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="3"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062256.1">
        <property type="nucleotide sequence ID" value="XM_003062210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2A1"/>
    <dbReference type="STRING" id="564608.C1N2A1"/>
    <dbReference type="GeneID" id="9687494"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5371"/>
    <dbReference type="eggNOG" id="KOG1537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QDVIHQP"/>
    <dbReference type="OrthoDB" id="195231at2759"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF1">
        <property type="entry name" value="HOMOSERINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861">
        <property type="entry name" value="HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00958">
        <property type="entry name" value="HOMSERKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="12">
        <location>
            <begin position="70"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="13">
        <location>
            <begin position="218"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH53968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="261" mass="27361" checksum="51BE5226E8EBEAF7" modified="2009-05-26" version="1" fragment="single">VSVPATSANMGPGFDSFGFAVDLENELILERGEFVVDVVGEGEDSLPRDESNAIIQAVKDGFSAIYPDRELPIENIRFKSVNRIPPARGLGSSSAALVSGLAAGLALAGQDLAAPQTKQLLLQLAADCEGHPDNVAPAIYGGFQVSINTGKQWVTQAVRLPDGMQAILFIPDFESLTSETRAALPKEIPVADAVYNISRAAMLVNSFSTGNLEALRYACQDVIHQPVRGAAFPLAELIDAAYSKGAHGAFLSGAGPTVLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2F7</accession>
    <name>C1N2F7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51511</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062081.1">
        <property type="nucleotide sequence ID" value="XM_003062035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2F7"/>
    <dbReference type="GeneID" id="9687520"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51511"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="13"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="389" mass="40998" checksum="325190652E8F2D0C" modified="2009-05-26" version="1">MTPMPPSQPPSLAPATTTTATTTSPASARSSSRSSPTSANASAPGTFRLSRANKTAPAPGAAATATAPATATAPATATATATNANAAIVDMKKVAKKDQREASIAIKRADAEKARAKTELNDALRLGTCAADHTFHHVSENRSLSSIHVYSRTNHSRPRHPSPEQVARAEKARAAELKLAAQKSEAQSRRLINQKKLQDTGGTVGIGVLLVSAIGTVWRSSGVPILIAGWIRNNYEDASATKTVYAVQARPCIYYTRPRTTSFARCSPFLEDFTSRRFSPPIPLCVSFNPDAPRRFATPTDAPPNSTPTSLRAGKHPRIHQWNDPIASPSAPDGIPTTVTIKAQKADAYHLKTAVAAASGLGSTGAEGIGHLAHVDPNLRFLRPLGAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2K8</accession>
    <name>C1N2K8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiamine pyrophosphokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51570</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062104.1">
        <property type="nucleotide sequence ID" value="XM_003062058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2K8"/>
    <dbReference type="STRING" id="564608.C1N2K8"/>
    <dbReference type="GeneID" id="9687332"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51570"/>
    <dbReference type="eggNOG" id="KOG4313">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WPDEISP"/>
    <dbReference type="OrthoDB" id="10261522at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044715">
        <property type="term" value="F:8-oxo-dGDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03676">
        <property type="entry name" value="NUDIX_Tnr3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031804">
        <property type="entry name" value="DUF4743"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622:SF8">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15916">
        <property type="entry name" value="DUF4743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="159"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="355" mass="37955" checksum="EEF71609996C6CF7" modified="2009-05-26" version="1">MASASTPPGAAPPASSSYSGHVPGFRARVAECNEITPADVATYTPLVVAGVEVGLMQRAFADALVAHGDGVFAMEEGKEDADASSPSSSSRSTIVTLDADATMTADARTAVVAPVMTSLRDAGVIEGWRDELFPVNAGYGSENLLLVERAAASLLGIRAYGVHVNGYVVMPDGSKELWVARRAKNKQTFPGKLDHVVAGGEFVPDWSPYDPASDAVSRGRTFLARLLSSGLPANMPPGTCVVKECEEEASMPPELAKNAKPVGVVTYNQNYNGCCKRDVLFCYDVELPEDFVPVPADGEVEGFERYTMERAMRTISQTTEFKTNCCVVIIDFFVRHGFVAPEEPGYAELVKSLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3D5</accession>
    <name>C1N3D5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52134</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062359.1">
        <property type="nucleotide sequence ID" value="XM_003062313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3D5"/>
    <dbReference type="STRING" id="564608.C1N3D5"/>
    <dbReference type="GeneID" id="9688032"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52134"/>
    <dbReference type="eggNOG" id="KOG4018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTSNPCF"/>
    <dbReference type="OrthoDB" id="277175at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23823">
        <property type="entry name" value="RWD_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040213">
        <property type="entry name" value="GIR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12292">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="2">
        <location>
            <begin position="10"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="300" mass="32230" checksum="E8CF99775CC1C4C9" modified="2009-05-26" version="1">MTDHLEDQAMEIEALESILMDDMSLVDGAEAIPGATHAPCYQIVVSPLGDGEDEDADDESQRARLGLVFSHTPSYPDEVPLLKCRSVHGLFDAELVAVHAALTRAAETSVGCPMIYDLTQVAKEWMRDRAGVVDVVEETPEQIASRLEEEAEARLRAMRATGTPVTPETWRAWEERFEAEETLARLSKGFHARGGAGGDAAAAETPPSAAPGKMKMTGRRYFEERTAAQLDVELDGGEGDREGGGGGGGGGDDDDDFAFSDDDFDDDDDALAAWLAARGGDGDGSENEEEEDEDEDYVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N454</accession>
    <name>C1N454_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="2">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_52416</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="2"/>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062487.1">
        <property type="nucleotide sequence ID" value="XM_003062441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N454"/>
    <dbReference type="STRING" id="564608.C1N454"/>
    <dbReference type="GeneID" id="9687927"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52416"/>
    <dbReference type="eggNOG" id="KOG3084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RNSKWPR"/>
    <dbReference type="OrthoDB" id="10249612at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006742">
        <property type="term" value="P:NADP+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03429">
        <property type="entry name" value="NUDIX_NADH_pyrophosphatase_Nudt13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050241">
        <property type="entry name" value="NAD-cap_RNA_hydrolase_NudC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049734">
        <property type="entry name" value="NudC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015376">
        <property type="entry name" value="Znr_NADH_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904:SF8">
        <property type="entry name" value="NAD(+) DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904">
        <property type="entry name" value="NUDIX HYDROLASE, NUDC SUBFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09297">
        <property type="entry name" value="Zn_ribbon_NUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="8">
        <location>
            <begin position="313"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="534" mass="56970" checksum="713894BEFA085CBE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4M3</accession>
    <name>C1N4M3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52611</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063023.1">
        <property type="nucleotide sequence ID" value="XM_003062977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4M3"/>
    <dbReference type="GeneID" id="9688463"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52611"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="323" mass="34675" checksum="E7BA10112D6B1959" modified="2009-05-26" version="1">MDAADGGDALLKMGLIEKLKDVARAVANADAVAAASTTAAAAAHEAALMCFPPEDFLPELPPLPKIPTTPSPPKARWPGTWRDVMTRNEPTVLPLHAVVPEIWRFRVRADDGAWRNLEGDELSDALKAVLDAALTPEALEQLTVEPPSLVEEETGTDVAFYEKGQERRGCRNLETKSVPAEETLPLASTRTFPPPCAYAGLRFALLALGDPAYEEAFAPKPREGTEEGDAEGDAAAETLIEPEPRDAWGSDALKSALAPEGELARRLTEFVWAERPPVREAAPGAEEDPNAEDAEDASPPRPGIETAEVRSPYTGSHTTAFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5A8</accession>
    <name>C1N5A8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_29541</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062935.1">
        <property type="nucleotide sequence ID" value="XM_003062889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5A8"/>
    <dbReference type="STRING" id="564608.C1N5A8"/>
    <dbReference type="GeneID" id="9688375"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29541"/>
    <dbReference type="eggNOG" id="KOG0198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QFPAARY"/>
    <dbReference type="OrthoDB" id="8693905at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF0">
        <property type="entry name" value="CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH52874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="231" mass="24127" checksum="4314993968A68ADB" modified="2009-05-26" version="1" fragment="single">MKCSVPFPGVIQGRPIGDGLSIGEVEAKVLSALPPHENVVKLHAAFLSDERNESYLLLSDVGDNLHASRERGEVSPKDVRRHARSVLRALKHCHAHGVTHRDVKGGNVLVGENGVATLIDFGVARHASVADTLPPDRYGTPGYQAPEVLLSDMSDSLKDDARYAAVDVFALGCTIFFLCVGRELYGPSPSGDGGLGASGVGVGGGGEAEVQLGARTKTKARATGAQVAVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5D0</accession>
    <name>C1N5D0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Micromonas-specific orphan protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_71086</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062946.1">
        <property type="nucleotide sequence ID" value="XM_003062900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5D0"/>
    <dbReference type="GeneID" id="9688590"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_71086"/>
    <dbReference type="OMA" id="GMAISEW"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1210"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1274" mass="135084" checksum="5A5BB408541718EA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5I8</accession>
    <name>C1N5I8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_36259</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063165.1">
        <property type="nucleotide sequence ID" value="XM_003063119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5I8"/>
    <dbReference type="STRING" id="564608.C1N5I8"/>
    <dbReference type="GeneID" id="9688810"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36259"/>
    <dbReference type="eggNOG" id="KOG0446">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KICHNCG"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001027">
        <property type="entry name" value="dynamin-related protein 3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="5">
        <location>
            <begin position="35"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="4">
        <location>
            <begin position="655"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="543"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="546"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="560"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="757" mass="81545" checksum="78508F03F0D868D6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5T7</accession>
    <name>C1N5T7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_42701</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063211.1">
        <property type="nucleotide sequence ID" value="XM_003063165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5T7"/>
    <dbReference type="STRING" id="564608.C1N5T7"/>
    <dbReference type="GeneID" id="9688863"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42701"/>
    <dbReference type="eggNOG" id="KOG0581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF9">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="99"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH52347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="464" mass="49270" checksum="493DF4956436C599" modified="2009-05-26" version="1">MSRPPRPAGLGLGLKLDGSFNLERSLNASADLSARLYASYNLTDDGIKLLSASAREFKLTSDGIEYGARGGDARASSATTGTSSRAENECAYRCASSDVRVFGVVGVGASGVVKRAIHVPSHRVIALKQMTVNDKERRRQIINEMRTLCDSPRVRGLVSFYGAFYSAENDTINIALEYVEGGSLEALLKRGGAIPCDVLGHITSGVTRGLEYLHRDRRVVHRDVKPGNVLMTSAGEPKITDFGISASIEPGGAGLLDSFKGTMCYMSPERVENGDYDFAADVWSLGLTVLECGLGRYPYDQNDGGPLGLMLQITQDDPPLPKEKDALRARGLTPSFEDFVRQARSIHWSPALYRDVSCVTTAQGEKVRGGRDISALLASRAASGAGALRRTVRTIDALPGGVDGGVTVFATGTLTSGGGGGGGGSGAFYTLVHEDWGGRGGGGDASSSGQFYVRNQLERWSSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5U5</accession>
    <name>C1N5U5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53044</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063427.1">
        <property type="nucleotide sequence ID" value="XM_003063381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5U5"/>
    <dbReference type="GeneID" id="9688656"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53044"/>
    <dbReference type="OMA" id="NDDLNEM"/>
    <dbReference type="OrthoDB" id="1915473at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36338">
        <property type="entry name" value="OS02G0495900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36338:SF1">
        <property type="entry name" value="OS02G0495900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="117" mass="13281" checksum="50B809B5160574D2" modified="2009-05-26" version="1">MSWIWEKSPLWRKIVRGTRTNRVAMGAFSLTTMFALPVAAGVAVMRWTTPDVSDDDAVALRKRVSMDARRLRANNNDDLNEMLDEVKRGVKNEERWRAALDGRTTSARTSSGTSLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N602</accession>
    <name>C1N602_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53110</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063453.1">
        <property type="nucleotide sequence ID" value="XM_003063407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N602"/>
    <dbReference type="STRING" id="564608.C1N602"/>
    <dbReference type="GeneID" id="9688892"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53110"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="279" mass="29308" checksum="F336039E8D6E8933" modified="2009-05-26" version="1">MTTVVPGVPPLRPPGVATRPRVGRRARSRAATAWRVASNPAARLGGGARGALAGGVRLFADSRSRTTSSPPLASTSTSRGFPTARASPRRETRTRAIGTETRAETECADGDENCVPPPGAVPLDATATDGVDAVAAEARGTMTRKTNNVAFVDKLRVDDATTAAMKKRSEAYATLDDIVLDFDPSLDTAQKLLLIGGYFSSSPTEVATRLAEVTAVAARLYAVWTWEEKTNVPDGSRTRASTLRDGIAGLGPVFVKMAQARSDSRRSPYDGVGVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6K8</accession>
    <name>C1N6K8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_36496</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063564.1">
        <property type="nucleotide sequence ID" value="XM_003063518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6K8"/>
    <dbReference type="STRING" id="564608.C1N6K8"/>
    <dbReference type="GeneID" id="9689005"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36496"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="6">
        <location>
            <begin position="1"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="236"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="272"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="288" mass="30276" checksum="813E00A966711FCB" modified="2009-05-26" version="1">MDPQQRLVLTACVSLSVFETACVIRDGSYPRREDWATMIGLSQVEYPRVSLADASPGPYYATGAHLSVTAGRVAFTLGFGGPAIVIDTACSSSLVAIGHAREYVCGRGFERAATTTTKSRGCVVGGVNLTIDATWSLACAAARMLAPDGRCKTLDSTADGYVRAEACGVLHVVGQSPRRAPSFLAVSGASANQDGRSSGLTAPNGPAQTTAIRLALASAEGNASDVTVLEMHGTGTARSGIRSKSAPPPPRCPPPTPFKPLSSPFKPLSNRGFHRDRRRRPRPRPRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6U7</accession>
    <name>C1N6U7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein RER1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RER1</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_49748</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the RER1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063616.1">
        <property type="nucleotide sequence ID" value="XM_003063570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6U7"/>
    <dbReference type="STRING" id="564608.C1N6U7"/>
    <dbReference type="GeneID" id="9689234"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49748"/>
    <dbReference type="eggNOG" id="KOG1688">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PYILYRW"/>
    <dbReference type="OrthoDB" id="448250at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004932">
        <property type="entry name" value="Rer1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743:SF0">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03248">
        <property type="entry name" value="Rer1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016013">
        <property type="entry name" value="AtER_Rer1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="193" mass="22069" checksum="033FF01469561255" modified="2009-05-26" version="1">MPSAEDSSRAAQLQAQLERKFQTYLDKSVPHVSQRWSAFACVALVYLVRAYFLKGYYIVTYGLGIYNLNLLIGFMTPQMDMTEDGPSLPTSGNEEFKPFVRRLPEFKFWYRSAKSVCVAFCMTFCPAFDLPVFWPILLMYFIMLLFMTMKQQVKHMLKYKYVPFSWGKKQYGKGGTGGASADAATAGLKKDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7M4</accession>
    <name>C1N7M4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49044</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063929.1">
        <property type="nucleotide sequence ID" value="XM_003063883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7M4"/>
    <dbReference type="GeneID" id="9689564"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49044"/>
    <dbReference type="eggNOG" id="ENOG502S2CN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTHRAYC"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="337" mass="35660" checksum="E47917C8C8AB27C1" modified="2009-05-26" version="1">MGVVEREAPYRLTRDEREAWERAKRRGPGVGGFAKGVGGGGFVELATKQRDDLAPRRHALVNTHRLYCDAINSVFVCVEQEPTKGEDEIVIDVSTLRVERDGAIRARIESVARAAAASETTTSGDGRGDGIVSVIDECGDEEPLDAMMRAVEASRVTELVVGPPEMSEMSDADVELSDGLSEKKKKSAAPPTAADVAAAEAAAAAAADAVRELKSLPGKTNADADVAELVRELLAKRATAEATRAAMEANAPEAIATAREAKARETRAIEEEARRMLGELPVHGLPERRVRVTCADRPTAKRVSKALAGANVLEALADAAAAEEEEEVVSSEEVATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N852</accession>
    <name>C1N852_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_53954</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064208.1">
        <property type="nucleotide sequence ID" value="XM_003064162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N852"/>
    <dbReference type="GeneID" id="9689463"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53954"/>
    <dbReference type="eggNOG" id="ENOG502RZCC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LWNEDTC"/>
    <dbReference type="OrthoDB" id="549039at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="407" mass="44307" checksum="29A008912DC28BB1" modified="2009-05-26" version="1">MNSGDVDEISGDGSTSPDLAAGSRLERFAADARDVFDEDVLRRLSVGDRAMLALVSRSMRDVVFTSSVGDVKDVAAVRRELGRMPNFVGSVGRLAWAKELGCPWNENTCAKAAEGGHLEVLQWARANGCPWDEDTCRAAAEFGHLEVLQWARANGCPWDEDTCRYAAKHGHLHVLQWAVANGAPWDEYTCSYAAGGGHLEVLQWAVANGAPWNEYTCRYAAKHGHLHVLQWAVANGAPWDEYTCSYAAGGGHLEVLQWAHANGAPWNTVYIDWAARGGHLEVVQWARANGAPWGEWTCNRAAGGGHLEVLQWARANGAPWDERTCAWAAEGGHLEVLQWAEANGCPWDADTCSGAAKGGHLEVLQWARANGAPWDARTCHEAALGGHLRVLQWARANGMPWESSWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N865</accession>
    <name>C1N865_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53968</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064213.1">
        <property type="nucleotide sequence ID" value="XM_003064167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N865"/>
    <dbReference type="STRING" id="564608.C1N865"/>
    <dbReference type="GeneID" id="9689471"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53968"/>
    <dbReference type="OMA" id="GFCTAYR"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="30"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="853"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1022" mass="108722" checksum="ADA4284FB848E7DD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1N872</accession>
    <name>C1N872_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_36886</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064031.1">
        <property type="nucleotide sequence ID" value="XM_003063985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N872"/>
    <dbReference type="STRING" id="564608.C1N872"/>
    <dbReference type="MEROPS" id="C19.094"/>
    <dbReference type="GeneID" id="9689660"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36886"/>
    <dbReference type="eggNOG" id="KOG1872">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FKSDAEY"/>
    <dbReference type="OrthoDB" id="333239at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="9">
        <location>
            <begin position="29"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="116"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="373"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH51653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="517" mass="55682" checksum="3FA22744AAE02B25" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N898</accession>
    <name>C1N898_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54005</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064231.1">
        <property type="nucleotide sequence ID" value="XM_003064185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N898"/>
    <dbReference type="GeneID" id="9689486"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54005"/>
    <dbReference type="OrthoDB" id="424712at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="2"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="386" mass="44929" checksum="93D2BA5DC81517A8" modified="2009-05-26" version="1">MAVTVFFFITGYVVYIGYADKVNEPEFGYWTFIKKRYIRLVPMHWLAILAFAPIVYVNYATIRDDYYLWQNKSSEYHMWAGWILNPFFMHTWIFSSMHYWNAPMWSVSTQCGFYFLFPFLARRMLKKIDKEETHVAQVYTLVTAGPNAGRSAGVVAELDAKKIDRNYVTRARWLFFWSIVIPVCAMSFFMSETFKKEWADPDAPDTDPGALEEDFNIVRAYFNARSWPPFRLPVFMLGMLFAAKRVRAHRNGDAANPDYVGYIGQQTDSLGWKLALWCVVSSALSCAYEDQKINVRMFNEFFLTLAVAYFVYGITVAPNDSWIARVVLRNRVMTFLGGLTYAAYVMQFVVWIYVNVVKTSRRTPRCRRRGSTASSRTRARIGWTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8C9</accession>
    <name>C1N8C9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54038</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064060.1">
        <property type="nucleotide sequence ID" value="XM_003064014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8C9"/>
    <dbReference type="GeneID" id="9689501"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54038"/>
    <dbReference type="OrthoDB" id="61280at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="70" mass="8018" checksum="6FBC0662F3C86916" modified="2009-05-26" version="1">MVRDGNPHAGYNKNALRGTLVGNWVEERALEADTGIFRYEVRRGSIALALASRRRRVGRRPRQEGSQRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8D7</accession>
    <name>C1N8D7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54046</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064250.1">
        <property type="nucleotide sequence ID" value="XM_003064204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8D7"/>
    <dbReference type="GeneID" id="9689506"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54046"/>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317">
        <property type="entry name" value="BLR8090 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317:SF1">
        <property type="entry name" value="ZINC-RIBBON DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="35"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="103"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="172" mass="19917" checksum="841210B664B28390" modified="2009-05-26" version="1">MAKKGQKGPGKPFIEWCAENGKRGERLANEFREELPTELTKGSHYKAKWKCLKCKHVWRAQVFHRTTSDKPRGCPKCANHMPLSKMNNFLAWCEKNGELGKKLSREYVDKDKPPTAVMKGSHYKVKWKCSSVECKHVWRAEMCHRTRSVRPSGCPACHPPGENLRKKRKRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8G5</accession>
    <name>C1N8G5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54077</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064263.1">
        <property type="nucleotide sequence ID" value="XM_003064217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8G5"/>
    <dbReference type="GeneID" id="9689704"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54077"/>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317">
        <property type="entry name" value="BLR8090 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317:SF1">
        <property type="entry name" value="ZINC-RIBBON DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="35"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="103"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="183"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="248" mass="28369" checksum="D7CF0F493C4B7687" modified="2009-05-26" version="1">MPKKGQKGLRKPFLEWCAENGKRGERLANEFREELPTELTYGSKYKAKWKCLKCKHVWRAAVNHRTRSVRPSGCPKCAHNAHVSKTHNFLAWYEKNGELGKKLSREYVDKDKPPTAVPKASHYKAKWKCSNVECKHVWRAEMCDRTRSDKPRGCPQCANHAPASKTNNFLTWCEKKGERGKKLLKEYVDPDKPPTAVTYGSKYKALWKCAECDHEWRATLNQRTHTRSANACPACKARESAGDEHAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8X4</accession>
    <name>C1N8X4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_9130</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064353.1">
        <property type="nucleotide sequence ID" value="XM_003064307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8X4"/>
    <dbReference type="STRING" id="564608.C1N8X4"/>
    <dbReference type="GeneID" id="9689794"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9130"/>
    <dbReference type="OMA" id="CVIREPA"/>
    <dbReference type="OrthoDB" id="10064100at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16655">
        <property type="entry name" value="RING-Ubox_WDSUB1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052085">
        <property type="entry name" value="WD-SAM-U-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573:SF1">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="70" mass="8217" checksum="3B3E8722302554B3" modified="2009-05-26" version="1" fragment="single">PSHFRCPITLCVIREPAVTPAGITYERAALMRWLEHQHTEPSTKQRLKRSHVVPNLTLRAMIEDWLQEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9L1</accession>
    <name>C1N9L1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54170</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064471.1">
        <property type="nucleotide sequence ID" value="XM_003064425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9L1"/>
    <dbReference type="GeneID" id="9689912"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54170"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="510" mass="52485" checksum="6904D7C6C2E7CF26" modified="2009-05-26" version="1">MTGPPGGADDHSPPSGGGGGRGASALAALMRARAASASSSSPAPTTTPTTTRDEASSRENARDAAIDAAARVFPELVAELAETIRRAVTTSGEDDVDDVESRDESAASTDDDLAHPDDDRRRHHRRHDDARKRANDDATITLPLPPTPDGRAALTNAAALSSLDLSGDDGVSARDGSLSLSRQIPLPPRPQSHQRRSVESALGGGPESWQSAGSVIVHATPTGSAAGRARARTRMRCSGDGEDARKRAARTATAAAATAAVGALLEEASGTETTRTTRATLDDDAMDALSDALAIAIARGARPLADAAAGALGTAACARRWRVASRTLRDAKRAISISISISISISTSASSESVAAAATRPLNVAAGAVVVAALDDLVGVAASLAPSSSSSSSSSSPTPPDDASGALYTLVPIRPRRRGERRSLRTFAVVSLRPHLAFNPRHRRLSTPTDAFQLHPDIRLYRTALRRDASVGGAVVDGEGRCGRRGARVRGGGAPLAARPTRGTFRGIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9T1</accession>
    <name>C1N9T1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_67754</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064788.1">
        <property type="nucleotide sequence ID" value="XM_003064742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9T1"/>
    <dbReference type="GeneID" id="9690229"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67754"/>
    <dbReference type="OrthoDB" id="10267855at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02208">
        <property type="entry name" value="cupin_RmlC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="JmjC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="141"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="508" mass="56552" checksum="EE728BDDBC58457A" modified="2009-05-26" version="1">MSDEDGDGDDDEEEYERVTFAEVLPAAADDDGVAAFFADRWCRDDVHSWSVIRPNDDDDARARRPDDDVLRRLRAGFCHGDAHAIIATCRKPSNAKFTEDEIEEMVGDVRSRGATLDLPFCFADGARELRRSLARMAFRADARRGARSSDNVAALECANDVEVGVYLSSARGAEAGWHYDANHNVTIQLYGSKEWHTVPSGNVNVESARGASDAPRNVFELRDAPPDVASASVTRVSPGAVIYVPPGCWHRVVPTEDDDGVCLSVDVRVGSVTELRWLMENLHTAMCGYTAREKATNATLMKNAVSDALLRKAMRFFSLLEASADKDFFFPIPRALPFEHDLSDGLDLCASLQFLHESLPPDIHEFLPASMVEAEGNLLYNSMVILSKTRAPDQNGVYLCMRSTSKLTNMDYMRFKILCPALLEPGIDLLIGEMCYHEGEDTEKRNAHRESVHAEHCEKDPTYRKAWGDLEDVLVWARVLKLNIPKEDMAVAEPSQSKGSVAPKRQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA10</accession>
    <name>C1NA10_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Heat shock transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_43666</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the HSF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064829.1">
        <property type="nucleotide sequence ID" value="XM_003064783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA10"/>
    <dbReference type="STRING" id="564608.C1NA10"/>
    <dbReference type="GeneID" id="9690148"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43666"/>
    <dbReference type="eggNOG" id="KOG0627">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000037">
        <property type="entry name" value="Heat stress transcription factor B-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0346">Stress response</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="11">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="106"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH51163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="188" mass="21043" checksum="06E4ACB386D85395" modified="2009-05-26" version="1">MSTRRERAPPFIRKLYHMIEDEVPPYDNVSWSESGREFTIHNVAAFSNTLLPRYFKHANFSSFVRQLNSYCFRKCDNVRWSFSNPYFVRGGESAMVRIRRRLPKPRNEEAASAAAARRDAASASAPAPPLEPSNDGAAADARNAALSLALKSAMDARAAAEIKTAVEAQARSIHWFPYDPVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA84</accession>
    <name>C1NA84_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54799</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064748.1">
        <property type="nucleotide sequence ID" value="XM_003064702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA84"/>
    <dbReference type="STRING" id="564608.C1NA84"/>
    <dbReference type="GeneID" id="9690303"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54799"/>
    <dbReference type="eggNOG" id="ENOG502RXVM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AEEYFFM"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46100">
        <property type="entry name" value="IMP2'P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46100:SF4">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="209" mass="22232" checksum="DA09D9F125FF2543" modified="2009-05-26" version="1">MAPLRRRKVAVAVDDSPGSMRATRYAAKSLLSRGDDVVLISAVHTTPSANPGARPRRLRSRLRFSPLTPSDAPTARSLTPPPSSPSAPQAEGERVLEHHRVQLLNTKMPSDRIKSVVVRCKVNESSARAVERAVDAEARSSVFTLSPDHVCLGSRGLGSLQTALLNAVGLGSVGEHVVKNVRVPVTVVPLSTPVPENITVRTGVSEHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAM1</accession>
    <name>C1NAM1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54971</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064930.1">
        <property type="nucleotide sequence ID" value="XM_003064884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAM1"/>
    <dbReference type="GeneID" id="9690428"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54971"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="80" mass="8753" checksum="069F4394B3BE1E1E" modified="2009-05-26" version="1">MPYPWEVSPGRSRQEDIFKESVDPHLDPAPREPSDAPVTAVSPPRGASNPEEEGAPPKVSRLKIPLFVDRSSVSTVFSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGE4</accession>
    <name>C1MGE4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_37659</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055310.1">
        <property type="nucleotide sequence ID" value="XM_003055264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGE4"/>
    <dbReference type="STRING" id="564608.C1MGE4"/>
    <dbReference type="GeneID" id="9680224"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37659"/>
    <dbReference type="eggNOG" id="KOG2810">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YEMHEVM"/>
    <dbReference type="OrthoDB" id="498197at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071479">
        <property type="term" value="P:cellular response to ionizing radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007268">
        <property type="entry name" value="Rad9/Ddc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04139">
        <property type="entry name" value="Rad9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="471" mass="49247" checksum="AE442D52191AE36F" modified="2009-05-26" version="1">MDLLLSGAPMRAFLKSVLCLSRIGSEVLFEATQEDGLSIKSINTARSAFCSIVLKPAAFEKYALTSGEATVQTCVLSKHLLASMRTTRMESLSLALDADQTTLSVTIVCNRGGVRKTYRIHVIEDAEHLKATIDAESMPVKLVLRPRGFSRLLSHFQPGQNDITIACLPETDGAERVERSFGVNANEPPPPRKNLKLTSYVDPNAPPSGALQTSIGMDTSEDAVLRYEAKKDETLEVTVNLKDLKAMVAFCEHVDVDVAIFADSPGAPVLVRPCAEFREIGGGGGGGGGGGGYGQQQHGGYPQRGQFDGLSGVPLDAELVLASMIPLQQELDKNEGGAHGGGDGGAGAGGGFGGESNEDEDALLLAAVTQAEQRMSAAASRGGEITERPARGKRRAAKDADASVGAAASTGIPDSVDDDGGGGGRAREAASVGNAGLAWAPGESTRADDTDDDDDGDQFVEPTPPDKRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGG1</accession>
    <name>C1MGG1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_37668</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054768.1">
        <property type="nucleotide sequence ID" value="XM_003054722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGG1"/>
    <dbReference type="GeneID" id="9680905"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37668"/>
    <dbReference type="eggNOG" id="ENOG502S7BP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FKTLAWG"/>
    <dbReference type="OrthoDB" id="45740at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="328" mass="35362" checksum="1F2C1DAFEF1CA490" modified="2009-05-26" version="1">MTASIASIATIATIALSSPHLPAALAGGYGTSLSYFERLERERVISEEPQTMAERDARAGARGRLAAAPSPSSARGVPLSLNAADDGTEDGAYSDLFVKSDPVGDGAAEDERRNKIDVRRWGRAAFQWGVIAAVAIRMRQANDRSSKVTKRLGLEGAASKALIGTRWRLTLDVGRERGTWMPPSWAASGVRVIAPIAIELAEGGVTRVVATGAFLPMKLSEGRWRLEGDALKFDVLMTTGMEKGDVTLPANESLHFRASAWGGAVSSRGTLLLRQTRWGFRKEWRMVGVFKAEKLSDGEDGVGDDQDYSGSSVFVDLPPMRVKQSEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGK3</accession>
    <name>C1MGK3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49846</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055336.1">
        <property type="nucleotide sequence ID" value="XM_003055290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGK3"/>
    <dbReference type="GeneID" id="9680826"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49846"/>
    <dbReference type="OrthoDB" id="19344at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="181" mass="18966" checksum="77DC2B3538B32F80" modified="2009-05-26" version="1">MTLGVVNGVLEATRYLPQVYSSYVNKGSGSLSYVRFFLCIGGGLGATIQKLVLGAFYTLVPIRPREDISTWLPPLVGHGLEVVIFVMNLYYDLSRGQGIIATGKGPGKYKGGGPGDRADETTPLVERMRSMRRDGGGGGGGGGGAGMGDGDGDGDGDGDGFSYPKRGCFSTPLGRKIIKYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGM3</accession>
    <name>C1MGM3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_61093</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054800.1">
        <property type="nucleotide sequence ID" value="XM_003054754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGM3"/>
    <dbReference type="GeneID" id="9680434"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61093"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="180" mass="20249" checksum="C90ACEB662DC6821" modified="2009-05-26" version="1">MWGWDVSARVASRVSGARVGPVIRVHERSDDVTQTKRRRSVAPAYLRERGLDVALERAPRPQRLRERARQHAVVLRENAQRRGAGRDVLALVDLLHVCFRSDGTRASRRRVFRLRGSGVATGSRRARARVRGDASRARRRASAIRAARASSACGPRASCGWRMDGSLRRGAVWAFREFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGU6</accession>
    <name>C1MGU6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_10761</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054839.1">
        <property type="nucleotide sequence ID" value="XM_003054793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGU6"/>
    <dbReference type="STRING" id="564608.C1MGU6"/>
    <dbReference type="GeneID" id="9680883"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_10761"/>
    <dbReference type="eggNOG" id="KOG2520">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAYLNQH"/>
    <dbReference type="OrthoDB" id="31113at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048256">
        <property type="term" value="F:flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09904">
        <property type="entry name" value="H3TH_XPG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09868">
        <property type="entry name" value="PIN_XPG_RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000030">
        <property type="entry name" value="Flap endonuclease GEN-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171:SF7">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00842">
        <property type="entry name" value="XPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG-I" evidence="12">
        <location>
            <begin position="10"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH60091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="237" mass="26607" checksum="D07E8A6A59B772E3" modified="2009-05-26" version="1" fragment="single">MHAEVQQLLTLFGIPYIIAPQEAEAQCAWLDREGFVDAVITDDSDAFLFGAKTIYRNVFESKKYVEFYDANRVDADLGLDRAKMAQLALLLGSDYTEGVTGVGIVNALEVVLNFPGVEGLTKFAEWVGESEFTGKPAAIREFKLKHRTLKKAWELPRDFPSERVLDAYANPSVDASREKFEWGEPDLDALRLFCGEHFAWRPTQTDDLLLPVVKMWETSDKQSRIDSFFAAAASANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGW1</accession>
    <name>C1MGW1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein bL32m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_12645</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054846.1">
        <property type="nucleotide sequence ID" value="XM_003054800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGW1"/>
    <dbReference type="STRING" id="564608.C1MGW1"/>
    <dbReference type="GeneID" id="9681253"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12645"/>
    <dbReference type="eggNOG" id="ENOG502S51Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2014905at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_bL32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051991">
        <property type="entry name" value="Mitoribosomal_protein_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="156" mass="16602" checksum="A75CB1F6FAFAD88F" modified="2009-05-26" version="1">MLRRAFHSIAATCAAAPRRGATPPASVAPWTRALTTTTTSRPSSDSTTGSFSGAFVAARPGTIFAPPSRGALPEDDARAPASPFALMAVPKRKVSPSRKGKRNQFRRIKFVGQAVRCRDCGKVKMPHVYCDRCSANVYEEEDLDGGGVPRAGVTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH48</accession>
    <name>C1MH48_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50049</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055431.1">
        <property type="nucleotide sequence ID" value="XM_003055385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH48"/>
    <dbReference type="GeneID" id="9681199"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50049"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="3">
        <location>
            <begin position="50"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="126" mass="13792" checksum="2BB4BD149F075003" modified="2009-05-26" version="1">MVLSNRAAAKAQAEWVLVGGKESKSVERGWIIVPDKSKDRKSGPIVEEPERADKVLASHGYCKRSEAKAWIRHGRVTFEGDVVKTCDAKVVVRLYDGVCVDGKPVPLTKKESSAKENDENDAPSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHU4</accession>
    <name>C1MHU4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_37960</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055552.1">
        <property type="nucleotide sequence ID" value="XM_003055506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHU4"/>
    <dbReference type="STRING" id="564608.C1MHU4"/>
    <dbReference type="GeneID" id="9680809"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37960"/>
    <dbReference type="eggNOG" id="KOG0371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EGYNWGQ"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="5">
        <location>
            <begin position="102"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="301" mass="34194" checksum="E6C6AA7D5133BF45" modified="2009-05-26" version="1">MVATLLEHEFLPEKDVLSLCERAKTLLTEESNVHAVRAPVTVVGDIHGQFHDLLEMFKMGGYAPDTNYLFLGDYVDRGYYSVETVTLVVALKVRYPDRVTIIRGNHESRQITQVYGFYDECMRKYGHAGIWKAFTDLFDYMPLTAVIENQIFCPHGGLSPSIDSLEDVRKIDRFQEVPHEGPVCDLVWSDPDDRTGWGMSPRGAGYTFGQDISEQFNHANGLKMIARAHQLVMEGYLWHHDQSLVTIFSAPNYCYRCGNQASIMEVSDDMTSEFLQFDPAPRRGEAQKTGDGPVRCPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHV3</accession>
    <name>C1MHV3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_50333</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055020.1">
        <property type="nucleotide sequence ID" value="XM_003054974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHV3"/>
    <dbReference type="STRING" id="564608.C1MHV3"/>
    <dbReference type="GeneID" id="9681124"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50333"/>
    <dbReference type="eggNOG" id="KOG4392">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RVEMRIQ"/>
    <dbReference type="OrthoDB" id="10248581at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06926">
        <property type="entry name" value="RNAP_II_RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037685">
        <property type="entry name" value="RBP11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF16">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="7">
        <location>
            <begin position="32"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="152" mass="16973" checksum="11554F53B10A814E" modified="2009-05-26" version="1">MNQPSRAEKFVLPDGVRKLTFTRDTKVANAGTFVVQKEDHTLGNAVRMQLHRDPEVVFSGYQVPHPSDNRIVIKVRAASAQSLGFLFLSAVRTRDPLALTARPPPSRPQVHTTKNSSPMQAMTEAVDCLRTEITDISQKFVDEVDSFRANQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI80</accession>
    <name>C1MI80_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_46306</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055624.1">
        <property type="nucleotide sequence ID" value="XM_003055578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI80"/>
    <dbReference type="GeneID" id="9680601"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46306"/>
    <dbReference type="eggNOG" id="KOG0061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QACINTS"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF41">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="12"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="197"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="694" mass="72268" checksum="31D985E33A71E882" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIL6</accession>
    <name>C1MIL6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61659</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055688.1">
        <property type="nucleotide sequence ID" value="XM_003055642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIL6"/>
    <dbReference type="GeneID" id="9680511"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61659"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="495" mass="51660" checksum="4DA895C031380A4F" modified="2009-05-26" version="1">MRVKEDAVKAAQLLHDPSKTHELYANERVYVPVKSTVVLDPPPRRTGDRAFAEGHGSDQPAGKVARRRLRARLKGGDGASFSAGFETGYDHGKDSKSQADAVASTASTANKIGRSHADAGGGKGDAGGDGACVTERVEAIVVAACRFQNSELADYAHRGAVTGRSSIACLDEKFRGINTTRWSSDCVLIHARCDDDDGDGVYGEDGEGAFESVETRRVARAIVDVCLDLHRFSLESGGGGLAVGVGIGSGFLDLRAGKLAGVESVARDAAARLCDLANDDGGGVRVDAAMYPLVRRSHLARVPVGVRPGGGADAKRVAAFAGYEISGRRAREDDDEFGGGGVAEGEAAEGGVVRDREKPTSGAPAAVPAFRGPLRRREEYRPGVVAAEGVSAPRSIAEMREVRAGFLRRFDACDSGARRVKTVAARREASASKKIQIAAANSRSTSRANSKATEGGDSAAMRVLTEFLSTQRLGTESGDGGASKAVFDRVIASAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIR0</accession>
    <name>C1MIR0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61694</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055709.1">
        <property type="nucleotide sequence ID" value="XM_003055663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIR0"/>
    <dbReference type="GeneID" id="9680640"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61694"/>
    <dbReference type="eggNOG" id="ENOG502SG0Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PYADEGW"/>
    <dbReference type="OrthoDB" id="199317at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049226">
        <property type="entry name" value="DUF6823"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20709">
        <property type="entry name" value="DUF6823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="195" mass="21581" checksum="D18751393F3D5871" modified="2009-05-26" version="1">MRALSSSPVLTSRGSLANARALARAPRAASNASRGRDLAAITRAGWFENDKDKAGRDTTWEAQQEILRKRRRGVNVESEISSRRKKVSGFLKGTLSKEETEAINKKNRDKANELSKEAFKGQKGWISIPGMAIGMPEFDGGERFDLRGPYADEGWVDPDDEGISNPFKGLFGGGKKKKEEEKPKPKPKKKGFFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ50</accession>
    <name>C1MJ50_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50810</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055251.1">
        <property type="nucleotide sequence ID" value="XM_003055205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ50"/>
    <dbReference type="GeneID" id="9680409"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50810"/>
    <dbReference type="OrthoDB" id="10668608at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="574" mass="61480" checksum="4387D9FE75F5493D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJE0</accession>
    <name>C1MJE0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_50904</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055298.1">
        <property type="nucleotide sequence ID" value="XM_003055252.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MJE0"/>
    <dbReference type="GeneID" id="9680497"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50904"/>
    <dbReference type="eggNOG" id="KOG0018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KHMDFQR"/>
    <dbReference type="OrthoDB" id="5575062at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03275">
        <property type="entry name" value="ABC_SMC1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028468">
        <property type="entry name" value="Smc1_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF12">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="13">
        <location>
            <begin position="583"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="501"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1011"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="188"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="764"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="905"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="501"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="521"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1014"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1039"/>
            <end position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH60550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1335" mass="149136" checksum="E11D2FEEFFBFA2A4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJJ1</accession>
    <name>C1MJJ1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 12">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MDH</name>
        <name evidence="15" type="ORF">MICPUCDRAFT_63993</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 12"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055830.1">
        <property type="nucleotide sequence ID" value="XM_003055784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJJ1"/>
    <dbReference type="STRING" id="564608.C1MJJ1"/>
    <dbReference type="GeneID" id="9681619"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63993"/>
    <dbReference type="eggNOG" id="KOG1494">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SDVFECT"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="52"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="196"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="57"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="166"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH59206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="362" mass="37439" checksum="743FC37B1AFEAC16" modified="2009-05-26" version="1">MAAAAMPVAAPVLSARASFRGSSKSSVRRSTAKAAATTTRRRVATATTSEYKVAVLGAAGGIGQSLSLLLKMNPMIAQLNLYDIQGTPGVAADLSHTNTQTKVTGYAGADSLADALKGCDLVIIPAGVPRKPGMTRDDLFEINAGIVKTLCEAVAANCPGALVNIISNPVNSTVPIAAEVFKKAGTYDPKKVFGVTTLDVVRSNTFVAEAKGLDVNDVDIPVVGGHAGITILPLLSQSYPATKFDADELEAMTVRIQNAGTEVVEAKAGAGSATLSMAYAAARMAEACLRGLSGEADVYECSYVASSVTELPFFATKVRLGPGGAEEVLPVGDLTEYEKGWLEKLIPELKGSIDKGIAFANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJT3</accession>
    <name>C1MJT3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_38364</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056268.1">
        <property type="nucleotide sequence ID" value="XM_003056222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJT3"/>
    <dbReference type="GeneID" id="9681641"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38364"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="321" mass="33944" checksum="24E02DB78C3A5DC6" modified="2009-05-26" version="1">MVEGLFKTSGSEALQDAGAGLSGSTKYLERVAAAAHGLRLTSSSSSPPPPPSRTTNDDATRVNAHATPTTKPVAVRALRTGLHATGWDVATKTLTVYGSVENLAEDANAPHAECVILRYMSNKTHMSETLRSIKTGMPRVHELRLEECALSSLSFLDELAALGLGGSGDADGRFIAKLSVSATGNPALRSLTLYRPYATRTLPSLETIDGVDVSAEDRDAARALFAPLDDEIAASASVVSSFQRQNAHQRDVTSIDPNDARALLTYARAATARAKAVAEKLRILDERWDGLVRGYAREGLELAAASSPGAVRKSVGETKCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJU9</accession>
    <name>C1MJU9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46493</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055884.1">
        <property type="nucleotide sequence ID" value="XM_003055838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJU9"/>
    <dbReference type="GeneID" id="9681439"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46493"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="692"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="735" mass="74032" checksum="64F384C40D1C8C64" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK68</accession>
    <name>C1MK68_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PKS2</name>
        <name evidence="10" type="ORF">MICPUCDRAFT_55217</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056330.1">
        <property type="nucleotide sequence ID" value="XM_003056284.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MK68"/>
    <dbReference type="GeneID" id="9681474"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55217"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PRERWDM"/>
    <dbReference type="OrthoDB" id="513994at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05274">
        <property type="entry name" value="KR_FAS_SDR_x"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7901"/>
            <end position="7920"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="671"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="763"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="2007"/>
            <end position="2082"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="2105"/>
            <end position="2553"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="2586"/>
            <end position="2882"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="3702"/>
            <end position="3776"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="3815"/>
            <end position="3889"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="3929"/>
            <end position="4003"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="4045"/>
            <end position="4495"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="4527"/>
            <end position="4803"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="5313"/>
            <end position="5388"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="5427"/>
            <end position="5880"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="5909"/>
            <end position="6241"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="6883"/>
            <end position="6961"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="6971"/>
            <end position="7478"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="7793"/>
            <end position="7877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="4">
        <location>
            <begin position="2586"/>
            <end position="2723"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="4">
        <location>
            <begin position="2741"/>
            <end position="2882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="3046"/>
            <end position="3066"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="4">
        <location>
            <begin position="4527"/>
            <end position="4654"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="4">
        <location>
            <begin position="4664"/>
            <end position="4803"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="4">
        <location>
            <begin position="5909"/>
            <end position="6043"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="4">
        <location>
            <begin position="6072"/>
            <end position="6241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="3055"/>
            <end position="3066"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="4">
        <location>
            <position position="2621"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="4">
        <location>
            <position position="2795"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="4">
        <location>
            <position position="4558"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="4">
        <location>
            <position position="4712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="7926" mass="848291" checksum="5066ABB701918593" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML11</accession>
    <name>C1ML11_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64742</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056477.1">
        <property type="nucleotide sequence ID" value="XM_003056431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML11"/>
    <dbReference type="GeneID" id="9681994"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64742"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="442" mass="47501" checksum="DCCE57BA77331FFC" modified="2009-05-26" version="1" fragment="single">MEEGGNCGTASADERIVPAYTAVSRSSFFTSTPRLDAPSAPSAPSAPSAPSARAASPVHPLVCGNDRSLSVCDVLVSSRGRSFRLADTFFYHSTAKNDDADVTNIAEAVAAAFGQNDELLKSSTYRGDVMLEAIIPHDFDPARDTLLMDVPFGYGESSGKTLEVKCERFRPGAAVAIPVPRWSEHVSKDAEEAEEVDVDGLDGDEEADRVRGGPLTAGVKQKSRALLETSAHISTHGGLEKNIVKWAEARGCAALECEDLSATMKLKDRSEKSIRRGESECSSASSEDEVDNKINDDESMQSRKDTQPSTQANVALGVDRIGSSQVRIVSPYEFHTSLAAALATNEASKRDSFDSARVETLPCQGNETAAACSVDATRRVNMDTGREGSIDGRRDSIDAIWFTDKQVKSSRNTIVRRTDSALDPRNHLLVETGSTSTAEFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM61</accession>
    <name>C1MM61_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_25774</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057343.1">
        <property type="nucleotide sequence ID" value="XM_003057297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM61"/>
    <dbReference type="STRING" id="564608.C1MM61"/>
    <dbReference type="GeneID" id="9682318"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25774"/>
    <dbReference type="eggNOG" id="KOG0922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FHEVMET"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000578">
        <property type="entry name" value="probable ATP-dependent RNA helicase DHX35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF136">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX35-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="60"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="273"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="738" mass="79804" checksum="C40A40A658C2628B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMA4</accession>
    <name>C1MMA4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56454</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056896.1">
        <property type="nucleotide sequence ID" value="XM_003056850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMA4"/>
    <dbReference type="GeneID" id="9682808"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56454"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="121" mass="12517" checksum="3B81188AF75A607B" modified="2009-05-26" version="1">MEKVKSIKAKVASGSEALLKKAKEEAAEAKEYTKKKAVELKPKLKAALAKAEPAVQEFFKSPTGEFLKNNPKAVIGVLTVLAFIGIPGAGPLAALVKIAGPLQAALPIIMTMAAPAAALLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMV8</accession>
    <name>C1MMV8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56676</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056996.1">
        <property type="nucleotide sequence ID" value="XM_003056950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMV8"/>
    <dbReference type="GeneID" id="9682912"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56676"/>
    <dbReference type="OrthoDB" id="545379at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="258" mass="27796" checksum="33A4F6EB18A455EF" modified="2009-05-26" version="1">MSSASVAARPLRTTSRAARDIVRESVRRARAVASSSERPPAPEARRRPIPIDRRTLLLASATAASSRALVLATLRADAADETDETERETTRASAGGARDDPDGRSASTSTATSTPDGDGATRDSGEDPWEGSYVKPALSVREYVEEIDKERDAAFATLRALCASSKFAALSNELVLAPTDDVRQAAYYLPWALVKLDEDAGVTTQRAWSEMRDALTYLDATAIDASRYDAEEEDVMAGIDRVERALDALVDSVPAAYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN53</accession>
    <name>C1MN53_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56785</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057519.1">
        <property type="nucleotide sequence ID" value="XM_003057473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN53"/>
    <dbReference type="STRING" id="564608.C1MN53"/>
    <dbReference type="GeneID" id="9682484"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56785"/>
    <dbReference type="OMA" id="ECECKDR"/>
    <dbReference type="OrthoDB" id="285219at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14361">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052617">
        <property type="entry name" value="Huntingtin-int_K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038922">
        <property type="entry name" value="HYPK_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184:SF2">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nascent polypeptide-associated complex subunit alpha-like UBA" evidence="2">
        <location>
            <begin position="79"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="121" mass="12620" checksum="6D5A449E9AA2071A" modified="2009-05-26" version="1">MGEHDDDEIEDVAPAQTGAAAEASKGLDRLGGRDDDGDDAAAADVVTPGARAEALRALLEEGKAEKEAEAARLRELAKVKIDAADVAVIVSEMEVEKKAAELRLREHGGDLAAALRSYVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNK9</accession>
    <name>C1MNK9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_38547</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056667.1">
        <property type="nucleotide sequence ID" value="XM_003056621.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MNK9"/>
    <dbReference type="GeneID" id="9682564"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38547"/>
    <dbReference type="eggNOG" id="ENOG502QPTZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MERTLKY"/>
    <dbReference type="OrthoDB" id="6351660at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026201">
        <property type="entry name" value="Cep290"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18879">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 290 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18879:SF20">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 290 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="345"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1719"/>
            <end position="1744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1936"/>
            <end position="1965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2015"/>
            <end position="2067"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="104"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="385"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="550"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="774"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="891"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="969"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1055"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1366"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1573"/>
            <end position="1621"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1756"/>
            <end position="1928"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="2074"/>
            <end position="2159"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="2265"/>
            <end position="2357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="2449"/>
            <end position="2476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1719"/>
            <end position="1742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1941"/>
            <end position="1954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="2052"/>
            <end position="2067"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2491" mass="272574" checksum="B1B97C56ECD1E65E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP69</accession>
    <name>C1MP69_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 70, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_56166</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057233.1">
        <property type="nucleotide sequence ID" value="XM_003057187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP69"/>
    <dbReference type="STRING" id="564608.C1MP69"/>
    <dbReference type="GeneID" id="9682208"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56166"/>
    <dbReference type="eggNOG" id="KOG0102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MGTDWKI"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11733">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000014">
        <property type="entry name" value="Chaperone protein DnaK HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000020">
        <property type="entry name" value="Chaperone protein HscA homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000003">
        <property type="entry name" value="Heat shock protein 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000001">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003520">
        <property type="entry name" value="PRK05183.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="702"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="674"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="720"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="732" mass="78650" checksum="9711203CA4F2C603" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPC2</accession>
    <name>C1MPC2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_32259</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056795.1">
        <property type="nucleotide sequence ID" value="XM_003056749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPC2"/>
    <dbReference type="STRING" id="564608.C1MPC2"/>
    <dbReference type="GeneID" id="9682699"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32259"/>
    <dbReference type="eggNOG" id="KOG2939">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MAKVKWD"/>
    <dbReference type="OrthoDB" id="498063at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990745">
        <property type="term" value="C:EARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019514">
        <property type="entry name" value="Syndetin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040047">
        <property type="entry name" value="VPS50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019515">
        <property type="entry name" value="VPS54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13258">
        <property type="entry name" value="SYNDETIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13258:SF0">
        <property type="entry name" value="SYNDETIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10474">
        <property type="entry name" value="Syndetin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10475">
        <property type="entry name" value="Vps54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 N-terminal" evidence="6">
        <location>
            <begin position="133"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Syndetin C-terminal" evidence="5">
        <location>
            <begin position="858"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="92"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="593"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="651"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="705"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="654"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="707"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1104" mass="119602" checksum="4D31D08F85B4974C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPM0</accession>
    <name>C1MPM0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Intraflagellar transport protein 72/74</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">IFT72/74</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_67097</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057604.1">
        <property type="nucleotide sequence ID" value="XM_003057558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPM0"/>
    <dbReference type="STRING" id="564608.C1MPM0"/>
    <dbReference type="GeneID" id="9683416"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67097"/>
    <dbReference type="eggNOG" id="ENOG502QS4E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RYWEELM"/>
    <dbReference type="OrthoDB" id="444379at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035735">
        <property type="term" value="P:intraciliary transport involved in cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029602">
        <property type="entry name" value="IFT74"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31432">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31432:SF0">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="198"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="310"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="449"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="604" mass="66112" checksum="A6D022B265693C2C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPQ8</accession>
    <name>C1MPQ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gcn5-like n-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NAT</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_32793</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ARD1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057625.1">
        <property type="nucleotide sequence ID" value="XM_003057579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPQ8"/>
    <dbReference type="STRING" id="564608.C1MPQ8"/>
    <dbReference type="GeneID" id="9683433"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32793"/>
    <dbReference type="eggNOG" id="KOG3234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EQHPSMR"/>
    <dbReference type="OrthoDB" id="10264728at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000034">
        <property type="entry name" value="N-alpha-acetyltransferase 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="177" mass="20329" checksum="E14A8A3ABD055EB1" modified="2009-05-26" version="1">MTTMRPFTCDDLFAYNDVNTDALTETFNLNFYLSYLARWPEYFTTAEGPGGSAPTGYVMGKAEGRGERWHGHVTAVTVAPSYRRMGLAKKLMRELEDVSEKVHDGYFVDLFVRRSNVNAIAMYEGMGYVVYRRVLNYYMGEEDALDMRKALPRDVEKKSGVPLKRPIQPHELEQDFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPW7</accession>
    <name>C1MPW7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57067</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058021.1">
        <property type="nucleotide sequence ID" value="XM_003057975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPW7"/>
    <dbReference type="STRING" id="564608.C1MPW7"/>
    <dbReference type="GeneID" id="9683060"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57067"/>
    <dbReference type="OMA" id="CARRIYE"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="496" mass="52772" checksum="FC697C9AB9A1476B" modified="2009-05-26" version="1">MAPKKREKAAAAPLSAYELEREARVKRNAEILARLRIPTLAAATRDPDASASSSGTSSDDADDDANGGANGGGDDARRRAKKLRKRRRERHRARAEEKAPGRSGSAATNRDRGEPSRRSSRPAAITSRANGKYADAAEDDTDDSDVSFYSSDEDEDADASGSADDDDDDEDEEEEDDDELDADGARRPPTRKRKKPSTKPKPSFAAPTSERARAAAAAARAASRPVGMWRKGGEDAPAFRAPYETGSAAAPGRGRVVPGLGGRVIPPPPPPPRPSAFAAAAANPAMRETPRPAEPDGGDVDLSGKTKKKKNGATRRPTPSLLHAVASEADVHDAWTALQPPSTTVAIERGAMRASDATIGASELRAAADAHGFCDCWRAWSPSSPTAATSRTPAAARARSCARGRGRACARRIYEGSWRESACGGRELGGRVGREFFEARGADANRRTNVARAKSSTRYRRSDHTSRHPARVVVAVVVVVFTWLFSLPRRLVSAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPZ9</accession>
    <name>C1MPZ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_16230</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057673.1">
        <property type="nucleotide sequence ID" value="XM_003057627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPZ9"/>
    <dbReference type="GeneID" id="9683476"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16230"/>
    <dbReference type="eggNOG" id="ENOG502QRUP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YLVGYPI"/>
    <dbReference type="OrthoDB" id="567232at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016730">
        <property type="term" value="F:oxidoreductase activity, acting on iron-sulfur proteins as donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009773">
        <property type="term" value="P:photosynthetic electron transport in photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039987">
        <property type="entry name" value="PGRL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31032:SF2">
        <property type="entry name" value="PGR5-LIKE A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31032">
        <property type="entry name" value="PGR5-LIKE PROTEIN 1B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="270" mass="28284" checksum="6D46E669388946FC" modified="2009-05-26" version="1">MWDDASIDGPSCLRLPPLHLSTRAELEEVYLQAKNTYFSGQPIVDDAFFDAIETRLKHLGSDVARKYPRCSRRDMTVFGDAEADYEQMGALAATWAGFVFLGIALMGLDVKSAVDAGALEGVFGFGGGGGDGPGLGLAETAGTTRPAARAPILAALGGFLAQTGCGKLASLRDGNTIAMSGDCPNCAERVYAFLPANSAAKTVKLKSDCHVCGRGLTFAADVQSSKDAPYGKVASGRIYLVSRTDDYYDGGAAPRWPPAKARAKEESGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ27</accession>
    <name>C1MQ27_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_15947</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057686.1">
        <property type="nucleotide sequence ID" value="XM_003057640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ27"/>
    <dbReference type="STRING" id="564608.C1MQ27"/>
    <dbReference type="GeneID" id="9683491"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15947"/>
    <dbReference type="eggNOG" id="KOG0544">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IHYTIKL"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="23"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="114" mass="12416" checksum="279BB7C45B7D5C3F" modified="2009-05-26" version="1">MPPPLIDVQIIRAGDGKYYPKPGETVAIHYTIKLASGKEVDNTYKRKQPFRFKVACGQVVKGWDAAVTQLSVGEKATCVFPARLAYGEKGFPGLIPKNAELHVTLELVAISMGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQS8</accession>
    <name>C1MQS8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="2">1.3.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_11009</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="3">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="6">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="4">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Dus family. Dus3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="2"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058180.1">
        <property type="nucleotide sequence ID" value="XM_003058134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQS8"/>
    <dbReference type="STRING" id="564608.C1MQS8"/>
    <dbReference type="GeneID" id="9683248"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11009"/>
    <dbReference type="eggNOG" id="KOG2333">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PWIFKEA"/>
    <dbReference type="OrthoDB" id="498058at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="7">
        <location>
            <begin position="5"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="229" mass="24506" checksum="64F3FF0A04693B42" modified="2009-05-26" version="1" fragment="single">GKLLLAPLTKGGNLPFRRLCVSLGCEVTVSEMVFARFALKKNPVELARLRKHDSETLFGVQIATNQITEGVNAGRLAHEAGADFVDLNCGCPIHETWKRGLGAALLKKPRKLERLVRGIADGIPIPLTVKIRLGAGSSEAPAHALAEAVENAGAAAVVIHGRTKEARYTKAANWETIGAIQAERGIPVVGNGDILTRYELNDRMGISNAHAAIVGRGALIKPWIFKEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRM5</accession>
    <name>C1MRM5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_58157</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058534.1">
        <property type="nucleotide sequence ID" value="XM_003058488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRM5"/>
    <dbReference type="STRING" id="564608.C1MRM5"/>
    <dbReference type="GeneID" id="9684340"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58157"/>
    <dbReference type="eggNOG" id="ENOG502QT4C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YTICHED"/>
    <dbReference type="OrthoDB" id="495392at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009640">
        <property type="term" value="P:photomorphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19821">
        <property type="entry name" value="Bbox1_BBX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051979">
        <property type="entry name" value="B-box_zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049808">
        <property type="entry name" value="CONSTANS-like_Bbox1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31832">
        <property type="entry name" value="B-BOX ZINC FINGER PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31832:SF68">
        <property type="entry name" value="B-BOX ZINC FINGER PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="B box-type" evidence="9">
        <location>
            <begin position="57"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="230" mass="25344" checksum="030E5699B8E7D5CC" modified="2009-05-26" version="1">MAKINRKIQQRVLVQGRDFPRTRTSHSAPPHATQSPTMKSVCEVCTTAPATLMCVADDAVMCGMCDKRCVNPVYTICHEDRAFLCRGCDVSLHSANEAVKKHRRFLYTGVTVALAPLGEKETATPREATDIVKEVPPMAAPIRPTVTQPQPQKKRKAVDIEDDFAVPTMSPDNSAGHGGVQWQSDEEFNSFVQDFVGKGEKNPDVNFDGFLDNFFDDVPLSDDFGVVPTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRN6</accession>
    <name>C1MRN6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_68245</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058540.1">
        <property type="nucleotide sequence ID" value="XM_003058494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRN6"/>
    <dbReference type="GeneID" id="9684345"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68245"/>
    <dbReference type="OrthoDB" id="10653676at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="502" mass="54358" checksum="8EAB3F8E750B9663" modified="2009-05-26" version="1" fragment="single">MVTTPPTARASGRIHVDVEAANVEKRLAPVFEYLNRYLPSSDDDGNGEIGDALHAAVKDAIDAARGGLRDARSLVFSALFFAWVASTPIVAPRDPFLATSKWKLPTGLFVLLVKKSGLEQNLRAKLRDDVPPHVSKYLDAELQGYDIEFIHESEGSKKLDENTVEESKPMSPRPLKVAAESDEGEAASPCGRCFAVVNEWLLLNEFATGDRISSAVESIKRIVREYGGEGRLTASMLLSSNAFHSARRAISRSDVSREKHLKVEQELIAILNRITTRRDGGRSEKTEHRSDDGLALAIDLLSPLLREPEMTLSRLVHTAAVHSSQAPFLVSAFTALPGLAMLKLEPTHAPFILEVLVRVLRNSPLELRGFNQLAGIKNLTVALFGEHAKEEESLGFFGHRFLAPRRSILDPRETLLMVLFPILVAGGSTSPSSNIDEGEVGASGSEGEMCALQILRALLVGDDASGATDVDPPLSSSGLKLLESTFPGAVLLSLGSYVDSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS14</accession>
    <name>C1MS14_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47376</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058605.1">
        <property type="nucleotide sequence ID" value="XM_003058559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS14"/>
    <dbReference type="STRING" id="564608.C1MS14"/>
    <dbReference type="GeneID" id="9684044"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47376"/>
    <dbReference type="OrthoDB" id="567749at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="338" mass="36340" checksum="C7E5B290E5CB2BA7" modified="2009-05-26" version="1">MPRPERDLRVASPGASSASSVFARRGRAARSSSSARRLLRAAALACCGFATLLLFGLRPPPLYDVFDLYSADAGNARGFVEAKHCHPFFAPKHERVVVASPPTRTKRLSGMRAGYCPCADDARGTTIAGAKGCGSKPVACGVECARRPVRGTKPPRCARKKRTSCEISGPRGRDGRSYHPNVKRPSRSVVAFAASFADARGPPLGVKLPGPAKKPRRDPTRDFVVRGERLSARDVTRVKRRLEAFKRAAPSYPATTFKGRGIVVVGGNSRRLQTSYFVAAHAIRRTGCALPIQLWFPEGEMPSCERVAALAELRVDVVSFAAFKDAGVGGGSSKRCYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS82</accession>
    <name>C1MS82_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein TIC 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_68383</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in protein precursor import into chloroplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Tic20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058638.1">
        <property type="nucleotide sequence ID" value="XM_003058592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS82"/>
    <dbReference type="STRING" id="564608.C1MS82"/>
    <dbReference type="GeneID" id="9684443"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68383"/>
    <dbReference type="eggNOG" id="ENOG502QUSD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="414558at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005691">
        <property type="entry name" value="Tic20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510:SF5">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16166">
        <property type="entry name" value="TIC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1001">Plastid inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="51"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="254" mass="27489" checksum="8F26308D67CE2F6E" modified="2009-05-26" version="1">MMAISSSVGAVATARATRAAPARATSAVVVRPRRRVASAAASANKIVARASSAPDHHHHHHHLAPRRVVASPARGRGAGARTTTTTAGYSPSYGGGGGSMIPVPDRFVALLPYLVPLLDGLRYSRFFFSQFPQAIFLLQPLQPIASMYFRIPFAGMISFFAIYLGIAENRNMSRFVRFNAMQAIILDIVLVLPGMVEYVLSPGSLRGMAFEMYKLCYNSVWVFVLAAFCLAAVGCMLGQMYKLPFIGDAADMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSF0</accession>
    <name>C1MSF0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">aspartate kinase</fullName>
            <ecNumber evidence="2">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_58461</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="2"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059042.1">
        <property type="nucleotide sequence ID" value="XM_003058996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSF0"/>
    <dbReference type="STRING" id="564608.C1MSF0"/>
    <dbReference type="GeneID" id="9684481"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58461"/>
    <dbReference type="eggNOG" id="KOG0456">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DNINIMM"/>
    <dbReference type="OrthoDB" id="4323675at2759"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009090">
        <property type="term" value="P:homoserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1320">
        <property type="entry name" value="Aspartokinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054352">
        <property type="entry name" value="ACT_Aspartokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042199">
        <property type="entry name" value="AsparK_Bifunc_asparK/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21499">
        <property type="entry name" value="ASPARTATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21499:SF59">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22468">
        <property type="entry name" value="ACT_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/glutamate/uridylate kinase" evidence="10">
        <location>
            <begin position="98"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Aspartokinase ACT" evidence="11">
        <location>
            <begin position="514"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="575" mass="61894" checksum="94B02389F0E3A788" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSG6</accession>
    <name>C1MSG6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_11097</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058676.1">
        <property type="nucleotide sequence ID" value="XM_003058630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSG6"/>
    <dbReference type="STRING" id="564608.C1MSG6"/>
    <dbReference type="GeneID" id="9684489"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11097"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THYMPPE"/>
    <dbReference type="OrthoDB" id="513891at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14014">
        <property type="entry name" value="STKc_PknB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF289">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE VIK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="207" mass="22723" checksum="4B6467498F997FE8" modified="2009-05-26" version="1" fragment="single">GEYKLLRKIGVGAFGEVAAYRNVNSGRSLAVKMLNKAAAVDEKAIEDLESEVLLLSMLSHPHLVSLEGVGYLPVSGKLFVATEFLGAGNLQKLVQEASVTPGRFNDADITKWMLQSAEALAYLHSRDPPIVHRDLKLANIVLDGNYDAKIIDFGLARMMGVEKVTTTVRESFGPGFKYMAPEVYKGEPMNERLDVYSLAMIAYELLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSJ6</accession>
    <name>C1MSJ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_39586</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058692.1">
        <property type="nucleotide sequence ID" value="XM_003058646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSJ6"/>
    <dbReference type="GeneID" id="9683778"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39586"/>
    <dbReference type="OMA" id="PMGPRGC"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="225" mass="18304" checksum="52C9CFD61B50BAE8" modified="2009-05-26" version="1">MMSSAGSGGASVAGAVSLDTAASTAASTADVSLDTAASTAASTAGAGAAASGAGAGAAASGAGAGAAASSAGAGAAASGAGAGAAASGAGAGAASSDAGAGAGAGAAASDAESSGAGAASSDAGAGAASSDAGAGAASSGAGAGAGSSGAGAGAGAGASIGASGAGAGAGASIGAPGAGAGAASCPSATRASVADESVAHAARITHARSARDRGMMTRASTRDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT40</accession>
    <name>C1MT40_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_10436</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="5">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058794.1">
        <property type="nucleotide sequence ID" value="XM_003058748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT40"/>
    <dbReference type="STRING" id="564608.C1MT40"/>
    <dbReference type="GeneID" id="9684233"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_10436"/>
    <dbReference type="eggNOG" id="KOG0133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RICINSP"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF18">
        <property type="entry name" value="SI:CH1073-390K14.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="7">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="254"/>
            <end position="258"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="424"/>
            <end position="426"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="434"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="527" mass="59397" checksum="FE50E2FF0270E609" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTI7</accession>
    <name>C1MTI7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47312</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058496.1">
        <property type="nucleotide sequence ID" value="XM_003058450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTI7"/>
    <dbReference type="STRING" id="564608.C1MTI7"/>
    <dbReference type="GeneID" id="9684310"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47312"/>
    <dbReference type="OMA" id="KHESAVG"/>
    <dbReference type="OrthoDB" id="10685356at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="834"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="383"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="703"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="838"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="929" mass="100468" checksum="C8DCC9ABA3D3FE6C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTK1</accession>
    <name>C1MTK1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_58101</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058876.1">
        <property type="nucleotide sequence ID" value="XM_003058830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTK1"/>
    <dbReference type="STRING" id="564608.C1MTK1"/>
    <dbReference type="GeneID" id="9683944"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58101"/>
    <dbReference type="eggNOG" id="ENOG502QWH1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AMNSIYE"/>
    <dbReference type="OrthoDB" id="298344at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040221">
        <property type="entry name" value="CDCA7/CDA7L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018866">
        <property type="entry name" value="Znf-4CXXC_R1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31169:SF23">
        <property type="entry name" value="OS03G0572250 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31169">
        <property type="entry name" value="OS05G0300700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10497">
        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Zinc-finger" evidence="11">
        <location>
            <begin position="155"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="62"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="267"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="369" mass="39622" checksum="3B06FF65B6E04A7E" modified="2009-05-26" version="1">MPRFGHKMVAADAREEMTAYEAERAARIEANKARMRDLGILDATARLRATDAAAAARRAAVRAARTPKGSDADGNPAYRVADRAAKPAVATRRSGRLSGASPDDAATTTRTTDRDDDVDRNPETYSPAQVAALGSATKTWTLFVDGYDANGNRIYDSAIGATCHQCRQKTVCAHTSCGGCGELRGQFCGDCLWMRYGEHVDEANALGAKWRCPPCRDLCNCSFCRQRKGWPPTGTLYRRAIKEGYASVAHYLVLNNRADEDVDVKTRGGAEEEGAADAADAAARDGRSPSGDDNARESGDVDAVDAVAVDAPPAAPVTPTASGPAKDDDDEFYDAKTRPSRMIVKVVRKMADAVTNPTATKRRRAMSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU34</accession>
    <name>C1MU34_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_18202</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PCNA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059428.1">
        <property type="nucleotide sequence ID" value="XM_003059382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU34"/>
    <dbReference type="STRING" id="564608.C1MU34"/>
    <dbReference type="GeneID" id="9684868"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18202"/>
    <dbReference type="eggNOG" id="KOG1636">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="534348at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043626">
        <property type="term" value="C:PCNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019985">
        <property type="term" value="P:translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000006">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA C-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="101" mass="11219" checksum="F20535DE792D4A71" modified="2009-05-26" version="1" fragment="single">SKDGVKFSTTGDIGQANITCRQNTSVDKEEQTVIELQEPVTLTFALRYLNSFTKATPLAPTVQLQMSKELPVVVQYLIADMGYVRYYLAPKIEDEETAGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU72</accession>
    <name>C1MU72_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58693</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059147.1">
        <property type="nucleotide sequence ID" value="XM_003059101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU72"/>
    <dbReference type="STRING" id="564608.C1MU72"/>
    <dbReference type="GeneID" id="9684884"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58693"/>
    <dbReference type="OMA" id="AVRNDNN"/>
    <dbReference type="OrthoDB" id="499002at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="558"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="633"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="767"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="910"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="449"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="236"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="560"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="635"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="646"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="676"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="807"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="857"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="910"/>
            <end position="964"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1002" mass="98129" checksum="B462FA5037C2CBF0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUA6</accession>
    <name>C1MUA6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_18118</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059162.1">
        <property type="nucleotide sequence ID" value="XM_003059116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUA6"/>
    <dbReference type="GeneID" id="9684602"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18118"/>
    <dbReference type="OrthoDB" id="2251794at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.10">
        <property type="entry name" value="endopeptidase domain like (from Nostoc punctiforme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051202">
        <property type="entry name" value="Peptidase_C40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041382">
        <property type="entry name" value="SH3_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47053">
        <property type="entry name" value="MUREIN DD-ENDOPEPTIDASE MEPH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47053:SF1">
        <property type="entry name" value="MUREIN DD-ENDOPEPTIDASE MEPH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18348">
        <property type="entry name" value="SH3_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82057">
        <property type="entry name" value="Prokaryotic SH3-related domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="NlpC/P60" evidence="5">
        <location>
            <begin position="105"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="192" mass="21328" checksum="5A45756AC289AA50" modified="2009-05-26" version="1" fragment="single">MAPPPEPEPKNGRWHQLLNFVALYDSPKCDTLATEATSGRWFRLFEKDDHHDGAVEILLREDYYRGWVEASSLFIHDDAHVSIQKEHDDLFAIVDDATGGVVDAKEAVGWVLREVSRARDDGTAYVWGGTMGPCFDCSGLTQGAFRDAGTWIPRDAYQQRAFATPVTDVRDAMPGDLLFFGDSDAVEDVGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUA7</accession>
    <name>C1MUA7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_45595</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059463.1">
        <property type="nucleotide sequence ID" value="XM_003059417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUA7"/>
    <dbReference type="STRING" id="564608.C1MUA7"/>
    <dbReference type="GeneID" id="9684603"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45595"/>
    <dbReference type="eggNOG" id="KOG2726">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HRMVRNS"/>
    <dbReference type="OrthoDB" id="2019491at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43116:SF3">
        <property type="entry name" value="CLASS I PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43116">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="2">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="289" mass="31783" checksum="BE15670AE96351F6" modified="2009-05-26" version="1">MIADDPSSADVPELASEVSDAVNALEGALEAWEARRLLGGTYDALGATVFIYAGAGGTDAQDWSEMLERCYLQWADRRGFAVRVEARTPGDEAGLKSVTLEIEGRYAYGYLASEKGTHRLVRTSPFNKGAFSFIHATRQTSFAAVDVMPTLEDKIEVTTMRSGGAGGQNVNKVETAVRMKHLPTGIVVRCEEERSQAMNRAKAIARLKAKLAAVAEERRLADVAAVRGDVVKAEWGQQIRNYVFHPYKMVKDVRTGMETSDVEGVMNGKLDEFQNAWLRWRASEKDDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUM0</accession>
    <name>C1MUM0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_27278</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059519.1">
        <property type="nucleotide sequence ID" value="XM_003059473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUM0"/>
    <dbReference type="GeneID" id="9684660"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27278"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QLMGWLT"/>
    <dbReference type="OrthoDB" id="6339427at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF49">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="49"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="490" mass="50945" checksum="6B83F9F378FB39B6" modified="2009-05-26" version="1" fragment="single">MGVLGALAAIVRSPIRAVRRRVTYGTFERDPEESPETTRAPLPWYTVRVVAFVAAIVALQGYDIGVMAGARLAMQRDRNFETWQSEIVVGCLNFVSAFGALAGGMAYNKHGAVRSVGAALALFVLGTAVAASAYSFTQAACGRAVCGVGVGLAFATCPAYLAEISPPARRGAVVAAGFELAIVSGLLLGYVASLIAVTCEDDDATRWRVSVGAPVPVAILLLALVPWMPESPRWLMREPNPRAAEALEVLRKTFGVGSPGGVKSKSPGNGRRRRVGSASGGWRGVFSDDPACRRALVVGVGLMFFQQACGTEAAVYYVPTLLRDAGWSSETDQIKAACAVGATKTFFVLVSAFVIDGLGGRRRTLLTSVAFSFACSVALAASVASVASPAATLTVLCLYVAAFSAGVGPVTWVVNAELWPRAVRARGTALGVAVNRATSGAVAMSFLSLSDALGGAGGAFACFAGVCLCHFIFAYALVPELKGRSLEQIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVG0</accession>
    <name>C1MVG0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65381</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060032.1">
        <property type="nucleotide sequence ID" value="XM_003059986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVG0"/>
    <dbReference type="GeneID" id="9685184"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65381"/>
    <dbReference type="OrthoDB" id="10678733at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="388" mass="40342" checksum="97B6AE89F407376C" modified="2009-05-26" version="1">MTRRADLVKTTAWFKTEEDPIEAMAKLAATIRDRAAYPGGVILHAEASARPGCTLLTVDVLARRLPDSDDASFCGPIADADREGMYDIDDEVDQVAARLAAVGANHGLEGTLDLAAQNATCSSRRRRVRYAGGFARGVHVDPTPNVRVGAKMRAAIRAANDPSTPMRVLRSDEYECFIMPSAPEGYSYVLRCRGRFVPMFATTPSYPETDTIVLHVTPTGAEGLAFLELVADAGGRETGDGAFGNAAPIICVPVFMSTDPALVKELTSDGRCARLGNTPALFNLGIALAAAAAVAEGEDPRVEGETASGEITFHAAAACATIGWATAVTRTIATLYDADAAYGGDGGFGGGGDGGDGTARTMSEGPDTDSQRNSSPCPDASTSAGTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW34</accession>
    <name>C1MW34_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_59609</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059854.1">
        <property type="nucleotide sequence ID" value="XM_003059808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW34"/>
    <dbReference type="STRING" id="564608.C1MW34"/>
    <dbReference type="GeneID" id="9685585"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59609"/>
    <dbReference type="eggNOG" id="KOG2231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PRCCICK"/>
    <dbReference type="OrthoDB" id="3838338at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057634">
        <property type="entry name" value="PAH_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056437">
        <property type="entry name" value="Znf-C2H2_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044288">
        <property type="entry name" value="ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938">
        <property type="entry name" value="ZINC FINGER PROTEIN 598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23202">
        <property type="entry name" value="PAH_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23230">
        <property type="entry name" value="zf-C2H2_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="7">
        <location>
            <begin position="721"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="341"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="422"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="539"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="775"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="553"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH55806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="829" mass="84719" checksum="C98017C5E265FD3C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWL7</accession>
    <name>C1MWL7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_5599</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Probable phosphatase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CTDSPL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059945.1">
        <property type="nucleotide sequence ID" value="XM_003059899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWL7"/>
    <dbReference type="STRING" id="564608.C1MWL7"/>
    <dbReference type="GeneID" id="9685131"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5599"/>
    <dbReference type="eggNOG" id="KOG1605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HRDYSTI"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000015">
        <property type="entry name" value="CTD small phosphatase-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="5">
        <location>
            <begin position="16"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="199" mass="22793" checksum="58A06600EF7C1D21" modified="2009-05-26" version="1" fragment="single">SCVPAKRAAILPKKSKAEPKNTLVLDLDETLVHSNLEATEDACDFSFPVTFNNQQHIVNVRKRPYLREFMEFAAARFEVVVFTASQRVYAERLLNTIDPEKRLIKHRLYRESCVLVEGNYMKDLSVLGRDLSRTIIVDNSPQAFGFQVDNGVPIESWFDDVSDRQLLKLMPLLARLSEVSDVRPLLRGKFNLGDRIERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWQ6</accession>
    <name>C1MWQ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_59214</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059669.1">
        <property type="nucleotide sequence ID" value="XM_003059623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWQ6"/>
    <dbReference type="GeneID" id="9685406"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59214"/>
    <dbReference type="eggNOG" id="ENOG502QUCQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IQARSRC"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="4">
        <location>
            <begin position="69"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="4">
        <location>
            <begin position="239"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="375" mass="39895" checksum="F764C0642AB58A8E" modified="2009-05-26" version="1">MASCARVASASASSSPRASPPPSSRRRAPTRARHHRTRRRSTIARDDDDAIDDDVATTTSSSSSIADAEALLISRLSSLPGRGANASAADEEAIAAALAVLEADGGIARPATRDEICGTWRLLYTSKSAFDPRNPLGKRADGSAPGIEGLFRAVFGDDAGEKMAAGMTSAASSSPIQRTVTSLEAFTIQARSRCYYTGLYFPAVVPLRPLPLAAFNPDAPTSTPHDSASDAPLNSAPTSRRRFARIVDAQQAIRLRGRDDDRVDQIVQFGDSGYLRLSAAASVDEASAPSRIDFAFDLAYFEIRSLPPFGFKPPGGPIRIPYPVPFKLLGDEAKGWLETTYLGADVRVSKGNKGTTFVLVREASDGTGTPLPYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX65</accession>
    <name>C1MX65_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_60045</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endomembrane system</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060638.1">
        <property type="nucleotide sequence ID" value="XM_003060592.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MX65"/>
    <dbReference type="GeneID" id="9686075"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60045"/>
    <dbReference type="eggNOG" id="ENOG502S5CA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48052:SF8">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE_THREONINE-PROTEIN KINASE FLS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48052">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH55407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2418" mass="264262" checksum="34889A04C5094351" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXF1</accession>
    <name>C1MXF1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_60136</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060383.1">
        <property type="nucleotide sequence ID" value="XM_003060337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXF1"/>
    <dbReference type="STRING" id="564608.C1MXF1"/>
    <dbReference type="GeneID" id="9686121"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60136"/>
    <dbReference type="eggNOG" id="ENOG502QQZG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="510988at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.890.10">
        <property type="entry name" value="Methyl-cpg-binding Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003888">
        <property type="entry name" value="FYrich_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01429">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51542">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50982">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MBD" evidence="5">
        <location>
            <begin position="42"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="210"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="368"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="418"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="618"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="426"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="758" mass="81475" checksum="13BC53B784EC96D8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXR1</accession>
    <name>C1MXR1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_34695</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060735.1">
        <property type="nucleotide sequence ID" value="XM_003060689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXR1"/>
    <dbReference type="STRING" id="564608.C1MXR1"/>
    <dbReference type="GeneID" id="9686172"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34695"/>
    <dbReference type="eggNOG" id="KOG0239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000113">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF28">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 2" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="5">
        <location>
            <begin position="345"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="688"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="21"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="297"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="692"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="708"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="426"/>
            <end position="433"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="742" mass="79477" checksum="3408132D8480A8AD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXU1</accession>
    <name>C1MXU1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_41039</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060453.1">
        <property type="nucleotide sequence ID" value="XM_003060407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXU1"/>
    <dbReference type="STRING" id="564608.C1MXU1"/>
    <dbReference type="GeneID" id="9686191"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41039"/>
    <dbReference type="eggNOG" id="KOG1454">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CFCEFNG"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689:SF56">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="79"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="405" mass="42841" checksum="A819D85E5CD26405" modified="2009-05-26" version="1">MATAKAQKDFTELVVEPFSDPDPKPLVGLLPARALADADSKFVTVTVRGEAVVVHYKESSPPPESQSQSRSPSPRDIDAVVCLHGANGSEFSFRNLLPRLASDAGVRAIAFDRPPYGLSSRPKLKKNGDAATDAATDAAGATATATATAAAHFVYTPEGQAELTLALMDALGVTRACVLGHSAGAPVALDAALRAPERIPTLALVAPAIFVGGDPLAGVPLDRALRFAWFRFLISQDGPGLNLVRGSVRRQLAAIEEGRTYANLSEDVRRAYARPTKAEGWDEGLLQSFRAGSFADASERLRREVPNALAPAKTKVVVVVGKNDRTTPPALSEALRDVLIECGVEDVRYELMPTASHLPMEEEAGGVRETFEALVVDVVLGGGGDGGVTTTTEKEEEEEEVTPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXW7</accession>
    <name>C1MXW7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60315</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060463.1">
        <property type="nucleotide sequence ID" value="XM_003060417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXW7"/>
    <dbReference type="GeneID" id="9686207"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60315"/>
    <dbReference type="OMA" id="DMCLDGY"/>
    <dbReference type="OrthoDB" id="497226at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="320" mass="35080" checksum="69380724C433F003" modified="2009-05-26" version="1">MAAATTSASISATLASRRRGDAMCQRNVAAACAKPRRAGPCRRPDAAAAGFRRRFEAACSSSSSSSSSSSPIDPDDVSAPAERDDYAAWKSSKDDETESFKRAARRDDDDFVVGAKPLDEKQLSQVMLQLLTNHSRGVPAAMLLDKVKKDMCLDGYKSVLVGIGRTRQWALAREVVEWVRAQGVEQGERGSEVLTSNWFVALIQRRVDEGEWDAAVEVFEYMRDFGGVPSGECVEMFARVTDHEGEMSEMTTSRCRAVGAWLASSDAGKALWHLSFGVPGMEAPRDVAPSKTIRIAMPSEEWDIDGDIDVLRDKLKDYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYD5</accession>
    <name>C1MYD5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartyl aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_1995</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.</text>
            <dbReference type="EC" id="3.4.11.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M18 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.21" evidence="4"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060266.1">
        <property type="nucleotide sequence ID" value="XM_003060220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYD5"/>
    <dbReference type="STRING" id="564608.C1MYD5"/>
    <dbReference type="MEROPS" id="M18.A01"/>
    <dbReference type="GeneID" id="9685993"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_1995"/>
    <dbReference type="eggNOG" id="KOG2596">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="INERDAW"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.250.10:FF:000001">
        <property type="entry name" value="Aspartyl aminopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002759">
        <property type="entry name" value="PRK02813.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF3">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH55035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="444" mass="47418" checksum="26CF2B9E1D92B6BD" modified="2009-05-26" version="1" fragment="single">INERDAWSLEPGGKYFFTRNMSAVCAFAVGGAYAPGSGFIVIGAHTDSPCPKLKPQTKLTSADFLQARSVRTQNYGGGLWYTWFDRDLGVAGRVLVREKGGAARHAVVKVDRPVMRIPSLAIHLDRSLNEGFKVNFQSHMAPVIASAVEEALGHGGGGATVDDSSSPAAKKAKGEKHHPVLLDLLADELECDADDILDFELQLCDVQPSAIGGARKEFIFSGRLDNLVSCFASLRALIDASGDAKSSVPRMGVRMMVHYDHEEVGSDSAQGAGSSMTEDAMRRITTSLSAGMAAGPGEEGVEERARRKSFVVSADMAHAVHPNYADKHEPGHKPKFGAGVVVKHNANQRYATDAVSSYLFKEIGERAGLPVQEFVVRSDLGCGSTIGPTLSTNTGIRTVDVGAAQLSMHSVREMCGAKDVEHAVKHFTAVYEGFTALDATLMVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYI9</accession>
    <name>C1MYI9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59914</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060575.1">
        <property type="nucleotide sequence ID" value="XM_003060529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYI9"/>
    <dbReference type="GeneID" id="9686013"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59914"/>
    <dbReference type="OrthoDB" id="733571at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31182">
        <property type="entry name" value="C2 NT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31182:SF21">
        <property type="entry name" value="C2 NT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="770" mass="81674" checksum="B56D7C9651903B94" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYX9</accession>
    <name>C1MYX9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_34846</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060861.1">
        <property type="nucleotide sequence ID" value="XM_003060815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYX9"/>
    <dbReference type="STRING" id="564608.C1MYX9"/>
    <dbReference type="GeneID" id="9686557"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34846"/>
    <dbReference type="eggNOG" id="KOG0691">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052814">
        <property type="entry name" value="Peroxisomal_DnaJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45006">
        <property type="entry name" value="DNAJ-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45006:SF1">
        <property type="entry name" value="DNAJ-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="202"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="273" mass="28377" checksum="D2A97D30AA977675" modified="2009-05-26" version="1">MATGGDANDRMMADAAKALTGYTGGGLSRTGATGAGEELDFNDVFSLRRPQNAMSGLSSGLQSAGKGVLAGAAALIAAPAIGAKAEGATGFFKGLGAGLVSAVVLPVVGVGVGATQIVRGIANTPEAIAEANAGKRWNRRTREWVTEDLVKEALKLAEIDDETILEKARERARAREAEERATSGGGGGGGGGATGGGVSETEFYDVLEVAPTASASEIKRAYYVAARKWHPDKCQDDPSAHERFQKIGEAYQVLSDDATRKKYDEKVRLVSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZD6</accession>
    <name>C1MZD6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">transketolase</fullName>
            <ecNumber evidence="4">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_34943</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="12">Binds 1 thiamine pyrophosphate per subunit. During the reaction, the substrate forms a covalent intermediate with the cofactor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061196.1">
        <property type="nucleotide sequence ID" value="XM_003061150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZD6"/>
    <dbReference type="STRING" id="564608.C1MZD6"/>
    <dbReference type="GeneID" id="9686379"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34943"/>
    <dbReference type="eggNOG" id="KOG0523">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ADYMRGS"/>
    <dbReference type="OrthoDB" id="10267175at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000004">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF2">
        <property type="entry name" value="TRANSKETOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="15">
        <location>
            <begin position="402"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="459"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="165"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="510"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="522"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="569"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH54846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="706" mass="75875" checksum="B0C9BB5BE9F13BC0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZK4</accession>
    <name>C1MZK4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60762</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061235.1">
        <property type="nucleotide sequence ID" value="XM_003061189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZK4"/>
    <dbReference type="STRING" id="564608.C1MZK4"/>
    <dbReference type="GeneID" id="9686408"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60762"/>
    <dbReference type="eggNOG" id="ENOG502SBK5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="231" mass="25987" checksum="F11ADE68B0E652E2" modified="2009-05-26" version="1">MRTRSSIGFNAIPENVAAVVFSHLGDDPRDRVALAQVSKVWRDAEKSDASLPGGSLSALSALSYELYIDGKYEHSIYWLRKAADRGDVDAMFEMAERYLYFDGFGETLDHKKASEWYERASGCGHAHATYELAWCYLYKEGDGVEKNEAKAVELYFKAAELGSGIAAWDLGLFYEQGLCGVAVNKKEALKWWRVAVERSDTRDTHDTRNIHAHAKAHVTKLERELSMTHAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZW0</accession>
    <name>C1MZW0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41396</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061287.1">
        <property type="nucleotide sequence ID" value="XM_003061241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZW0"/>
    <dbReference type="GeneID" id="9686726"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41396"/>
    <dbReference type="eggNOG" id="ENOG502S08K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WNELTVG"/>
    <dbReference type="OrthoDB" id="531455at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="263" mass="27963" checksum="8F51C5E8F67E2B81" modified="2009-05-26" version="1">MTLHAAATYRAPVACRATTPTPTRRRATTTRRATRTRAAADPMAVEDGTIDLVVSTEAAKKTLQFDKVTVNEAEGPVIFVTGVAIGSEAEAAGVTPGQRLVAVSDPINDGELWFLDGSERLAFVLDAIRSAQNRPETTIIVETEVSITKELVDRARGVDTEEEARAAAAKAKAADAAAAPRREVTAADLAPRGSSPPGASDKPREKPREREDLYSDKWAGDEYVGEGFWNELTVGAAIFVAVPAVIVTLAVTTRGTLWDTTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0U8</accession>
    <name>C1N0U8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine(9)-N(1))-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.221</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_11492</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>guanosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43156"/>
            <dbReference type="Rhea" id="RHEA-COMP:10367"/>
            <dbReference type="Rhea" id="RHEA-COMP:10368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.221"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.221" evidence="1"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061700.1">
        <property type="nucleotide sequence ID" value="XM_003061654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0U8"/>
    <dbReference type="STRING" id="564608.C1N0U8"/>
    <dbReference type="GeneID" id="9687139"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11492"/>
    <dbReference type="eggNOG" id="KOG2967">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="278300at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052905">
        <property type="term" value="F:tRNA (guanosine(9)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18089">
        <property type="entry name" value="SPOUT_Trm10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028564">
        <property type="entry name" value="MT_TRM10-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038459">
        <property type="entry name" value="MT_TRM10-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007356">
        <property type="entry name" value="tRNA_m1G_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563">
        <property type="entry name" value="TRNA (GUANINE-9-) METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563:SF13">
        <property type="entry name" value="TRNA METHYLTRANSFERASE 10 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51675">
        <property type="entry name" value="SAM_MT_TRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase TRM10-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="134" mass="14176" checksum="3D6619BFA70161B4" modified="2009-05-26" version="1" fragment="single">LVFDMAYDASATRAEIGALTRQVSMCVAANKRAKTPFLLAVAAPPGNNDDELPPASNSWRALPWESWGARVVDLDDENENENSAAASLTADARRVVYLTADSPNVLTDVAPGTALVLGGVVDHAEKPGMSLRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0W9</accession>
    <name>C1N0W9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_20451</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sterol desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061467.1">
        <property type="nucleotide sequence ID" value="XM_003061421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0W9"/>
    <dbReference type="STRING" id="564608.C1N0W9"/>
    <dbReference type="GeneID" id="9687148"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20451"/>
    <dbReference type="eggNOG" id="ENOG502QQ3D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CEMTMPR"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021940">
        <property type="entry name" value="CER1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12076">
        <property type="entry name" value="CER1-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="7">
        <location>
            <begin position="129"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Very-long-chain aldehyde decarbonylase CER1-like C-terminal" evidence="8">
        <location>
            <begin position="449"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="628" mass="71115" checksum="DEA24114409B3FD9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1G7</accession>
    <name>C1N1G7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48312</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061813.1">
        <property type="nucleotide sequence ID" value="XM_003061767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1G7"/>
    <dbReference type="GeneID" id="9687252"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48312"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032707">
        <property type="entry name" value="MYCBPAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14646">
        <property type="entry name" value="MYCBPAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="424" mass="45282" checksum="DD130F3BEC8591F8" modified="2009-05-26" version="1" fragment="single">MFMDKWLVETRPNLRKGPMPAVTLRGFATPEDEHSHPRRGLTNEMERKEMVHKVSTAVSKVLRAVKTPATATATDLTKRGPESNADAALWRAGNRGRRPRVYYTHEGFVALREIREKARAKRFAIEGEPEPPPPPAEGEEPPPDESVWIGAVDAVAKELDSLQAAIENNPDYVDPDAPPPPAEGEDAAPFETPSDVLMNLRGDYERAIEEALLPEGRADLLAVAASESLANALSGVDDAAAAAMAAHGPPPEEEEKEGGDAEADPGGDAAQAPPAGTPPRKPPWKPRYLRQLRESVSAMLCDAVETFEEIAIGRAEAEVNKESLRRVREMRETRANDTVTARGGSGPHAELSVSEAIGLSPGMNGKGALEWDVYDALRRRKMLLGREPSGTMSALASPVAASPSPAKSARSGDSASGSGAGTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1H2</accession>
    <name>C1N1H2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_20393</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061818.1">
        <property type="nucleotide sequence ID" value="XM_003061772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1H2"/>
    <dbReference type="STRING" id="564608.C1N1H2"/>
    <dbReference type="GeneID" id="9687257"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20393"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FDTRMDI"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF12">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="111"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="546" mass="60548" checksum="AA651490D38A2134" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1I0</accession>
    <name>C1N1I0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_48319</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061824.1">
        <property type="nucleotide sequence ID" value="XM_003061778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1I0"/>
    <dbReference type="STRING" id="564608.C1N1I0"/>
    <dbReference type="GeneID" id="9687263"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48319"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46699">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE STN8, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="74"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="274" mass="28933" checksum="84B311973255746C" modified="2009-05-26" version="1" fragment="single">MASLRAAPPPTTTTTSSSSSSRRPRVASRRATPPPLPARRASSHVARAEYSYDVGSYDPEMDGFVPPEVSLSTLAVGAKIGEGSFGVVYRGVVTEEDASPRDVVVKEYKKSVRGRDWYSFYCDERDICRRLVGCAGVAPFAGVAGSDAYLVWEHVGDETLGSVLDAGRGVKGVREAIGDGRGGRGGRDDAETFRAIAAGLCEAAIAMHERGVVHRDVKPDNVLLTSVITSANVSDDDAVLALCDLGGAADFETGQGCDGREAIFDPVYGAPEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1N8</accession>
    <name>C1N1N8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_21054</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062150.1">
        <property type="nucleotide sequence ID" value="XM_003062104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1N8"/>
    <dbReference type="STRING" id="564608.C1N1N8"/>
    <dbReference type="GeneID" id="9687387"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21054"/>
    <dbReference type="eggNOG" id="KOG1149">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PHWRFKL"/>
    <dbReference type="OrthoDB" id="428822at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000045">
        <property type="entry name" value="Glutamate--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049940">
        <property type="entry name" value="GluQ/Sye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43311">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43311:SF2">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="An anticodon-binding domain of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="11">
        <location>
            <begin position="43"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class I anticodon-binding" evidence="12">
        <location>
            <begin position="390"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH53862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="536" mass="59155" checksum="74491E73D33D5E36" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1U1</accession>
    <name>C1N1U1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Midasin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_21219</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the midasin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061971.1">
        <property type="nucleotide sequence ID" value="XM_003061925.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N1U1"/>
    <dbReference type="GeneID" id="9687618"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21219"/>
    <dbReference type="eggNOG" id="KOG1808">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KRCAIAP"/>
    <dbReference type="OrthoDB" id="5186at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000142">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000582">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001384">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001887">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040848">
        <property type="entry name" value="AAA_lid_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041190">
        <property type="entry name" value="Midasin_AAA_lid_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103:SF2">
        <property type="entry name" value="MIDASIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103">
        <property type="entry name" value="MIDASIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17865">
        <property type="entry name" value="AAA_lid_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17867">
        <property type="entry name" value="AAA_lid_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="305"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="684"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="976"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="1318"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="1651"/>
            <end position="1923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="209"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1021"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="275"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1039"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1926" mass="205447" checksum="6C3AF69844C241F8" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1V0</accession>
    <name>C1N1V0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51741</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062181.1">
        <property type="nucleotide sequence ID" value="XM_003062135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1V0"/>
    <dbReference type="GeneID" id="9687418"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51741"/>
    <dbReference type="OMA" id="RYCVANA"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="254" mass="27199" checksum="2CF6984F6574F8B4" modified="2009-05-26" version="1">MRILADTQNALAAFRAGLTPPVLAFLAATWVLAALNPTPESWAATCASRGLISRGFLDILSLRTSSSVCSNGGLSRAFFLRQGAYTHHDLLIASVVETSRDPRARYLGVVGLWIKFPFGLGWLAGLFVNVYRVHAFVTKLLCVGIVALAAMRVVTLVKTTLLYVVYAVVALVALPKLTGAPLHAVVIGLGVLAYGLKLQPGIQASLMSLMNVLMPPTRQRKAQLSVLKRLDALEAKAKDEVAASDDDDDDDDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1W2</accession>
    <name>C1N1W2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_8198</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061982.1">
        <property type="nucleotide sequence ID" value="XM_003061936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1W2"/>
    <dbReference type="STRING" id="564608.C1N1W2"/>
    <dbReference type="GeneID" id="9687628"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8198"/>
    <dbReference type="OrthoDB" id="513226at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110102">
        <property type="term" value="P:ribulose bisphosphate carboxylase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.210">
        <property type="entry name" value="Chaperonin-like RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038052">
        <property type="entry name" value="Chaperonin_RbcX_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003435">
        <property type="entry name" value="Chaperonin_RcbX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791">
        <property type="entry name" value="CHAPERONIN-LIKE RBCX PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791:SF1">
        <property type="entry name" value="RUBISCO CHAPERONE RBCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02341">
        <property type="entry name" value="RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158615">
        <property type="entry name" value="RbcX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912328" evidence="4">
        <location>
            <begin position="34"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="129" mass="14650" checksum="40BAD77EECCD3138" modified="2009-05-26" version="1" fragment="single">LFANGVGPQVPEAKAARSMKLLFTMVALRVVLAQEEGFGNECHDDPSYTELYDDLTTYLGKNPLNAGGDGEAWLRELMRHDKLHCRLAAVRLLEVRDVYASREFDWGEVRREALEDMEATRIAMLNEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N235</accession>
    <name>C1N235_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_70106</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062020.1">
        <property type="nucleotide sequence ID" value="XM_003061974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N235"/>
    <dbReference type="GeneID" id="9687460"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70106"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="501" mass="51997" checksum="C8C4608CD6D89BBB" modified="2009-05-26" version="1">MRGSTSDVSGSSSSALNAGAVGFVAAAKAVASASASPLPLPAGAAFSFSPHSSESLALPASREFDGGDTFCFFPDGTSPRAGSSYTVAAARISSGASFFFCFFAGGDRPSTPVAPGSAGRFFATVFFDAPPQSADDAAFFASLNGFIFFFASSFFVLCSAFSRSLRARSSAFSRSFLALASSFSCSFRSFSSAFSCSFRSFSSAFSCSFRSFSSAFSCSLRSRSSSRCASFSARSASFFRRSSSRIASRAFRASAAAAARSAASSALVGFFGFIAGGLMRYSRSRSRRRLSVSLGGIVFPASVDLPSSASSSGFSGHGASPAFANDSVSSARSASNCSSSASCDHGENPCRSDPRRRSASKDSFHHDTRLPFAMTGTTSRNVASSFSSGIGGTYSAGRVAISAASRAMSSSDFSTSIASDSAARSLRHFVARCHPEASRFQTFTRASATRASSVTASAVSAKDSSHALRVDRRQVESKGVRYEVERGVAACRDRTRGMSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2H0</accession>
    <name>C1N2H0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_44749</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062087.1">
        <property type="nucleotide sequence ID" value="XM_003062041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2H0"/>
    <dbReference type="STRING" id="564608.C1N2H0"/>
    <dbReference type="GeneID" id="9687526"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44749"/>
    <dbReference type="eggNOG" id="KOG1301">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VNDLRAW"/>
    <dbReference type="OrthoDB" id="10251230at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="620" mass="66278" checksum="07B561978B8215C0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N307</accession>
    <name>C1N307_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cilia- and flagella-associated protein 36</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Coiled-coil domain-containing protein 104</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_8917</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CFAP36 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062295.1">
        <property type="nucleotide sequence ID" value="XM_003062249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N307"/>
    <dbReference type="GeneID" id="9687968"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8917"/>
    <dbReference type="eggNOG" id="KOG4511">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272687at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097546">
        <property type="term" value="C:ciliary base"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1520.10">
        <property type="entry name" value="ADP-ribosylation factor-like 2-binding protein, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023379">
        <property type="entry name" value="BART_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042541">
        <property type="entry name" value="BART_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038888">
        <property type="entry name" value="CFAP36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21532:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21532">
        <property type="entry name" value="PHOSPHODIESTERASE HL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11527">
        <property type="entry name" value="ARL2_Bind_BART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BART" evidence="10">
        <location>
            <begin position="2"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="89" mass="10291" checksum="CA54E46422747440" modified="2009-05-26" version="1" fragment="single">LVFDGEEENKLSYTDVHQQFKDLVEKLLTGFLSDLGIVPEQFVHVVSNAAKTELNEFIITSILTVDDFTQFKAMMVKRNRDLTDEVRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N312</accession>
    <name>C1N312_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_3013</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2</text>
            <dbReference type="Rhea" id="RHEA:63388"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:61715"/>
            <dbReference type="EC" id="1.17.99.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:63389"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Porphyrin-containing compound metabolism; heme A biosynthesis; heme A from heme O: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062299.1">
        <property type="nucleotide sequence ID" value="XM_003062253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N312"/>
    <dbReference type="STRING" id="564608.C1N312"/>
    <dbReference type="GeneID" id="9687739"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3013"/>
    <dbReference type="eggNOG" id="KOG2725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AFVCYSW"/>
    <dbReference type="OrthoDB" id="1726137at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120547">
        <property type="term" value="F:heme A synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023754">
        <property type="entry name" value="HemeA_Synthase_type2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH53118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="377" mass="41325" checksum="2317D9200B7849E1" modified="2009-05-26" version="1" fragment="single">LVRGGAFAENAVAAWLAGGCVWVFSLVVLGGATRLTRSGLSMTDWKFEWERAPSTDVEWRAEFDKYKRSPEYVKTNVGMTLEEYKFIYWMEFGHRMWGRGLGAYFALPLAVFAAAGFVTPGLMARLAGLFTLGACQGMIGWWMVKSGLTLRRAAERNEIPRVSPYRLATHLTGAFTIYVGMLWTTLSVAFPGCAIEDHARRSMTWVAGDSGARRIAMLALEAARKARQTIVPLAGLIATTALSGAYVAGMDAGRAFNTFPLMGGRVVPEEYFDMWEKYGWRNFFENTAAVQFDHRALAVTTLLAVTYAWGTLRGNPRLPAVSSLALDAVMVVTLAQVGLGISTLLYHVPVSLGSLHQANALLLMTTVVGLLYTLRVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3A7</accession>
    <name>C1N3A7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_68592</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062346.1">
        <property type="nucleotide sequence ID" value="XM_003062300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3A7"/>
    <dbReference type="STRING" id="564608.C1N3A7"/>
    <dbReference type="GeneID" id="9688017"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68592"/>
    <dbReference type="eggNOG" id="KOG1824">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6260732at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010265">
        <property type="term" value="P:SCF complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039852">
        <property type="entry name" value="CAND1/CAND2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12696">
        <property type="entry name" value="TIP120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25782">
        <property type="entry name" value="TPR_CAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="278" mass="28957" checksum="62FE078A4FB43C6A" modified="2009-05-26" version="1">MDASDKSAAARTPETLTLRVSALAFVRLAIETHAVDAFAPHVNALAPCVFRASGDAYYKIAAEAMRACAALVPVLAAARAAAAAVVDASVAAELAAACASRVARVDQDQEVKEAAIACAGAMLAELGEDGVGEAVARETLSLLVDRLKNETTRLCAVKAIGRAAASPVKLNLKMNDVASRAATELAGFLRKANRPLRQAAAAALAALATNHAAALSGAFYTLVPIRPCWRGERDSLRTFAGASLRTSLAFNPRPRRLSTPSDAFELHPPIALYGTTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3X0</accession>
    <name>C1N3X0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_21673</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062688.1">
        <property type="nucleotide sequence ID" value="XM_003062642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3X0"/>
    <dbReference type="GeneID" id="9687888"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21673"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TGSHMES"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904659">
        <property type="term" value="P:D-glucose transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000118">
        <property type="entry name" value="D-xylose-proton symporter-like 3, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050820">
        <property type="entry name" value="MFS_Sugar_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48023">
        <property type="entry name" value="D-XYLOSE-PROTON SYMPORTER-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48023:SF4">
        <property type="entry name" value="D-XYLOSE-PROTON SYMPORTER-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="58"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH53507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="510" mass="53460" checksum="C4DC6BC58910B2D2" modified="2009-05-26" version="1">MLRHRHDAWSPVARASVDDYDAELARGDDDARRLLDDDRGGGERPIADDVDVRATALLFIFPAIAGLLFGWDIGSTSGALQSLTDPNTAGMDWYALDPFQRGLVVSTSLAGALVASATAALKLGDKLGSRKELQLAALLYAGGALVQGGAISLETLVLGRFTYGLGIGFAMHGAPLYIAETAPTKVRGLLISLKECFIVGGILLGYAGGYLIEGEEGGWRVLLSSSVALSGVLSLGLLKLPDSPRWSLQRGGDANDARAALKILRGDKATPGTIDAEMRAMTAASEKSGVGGVGELLRKKNVRPLFVGLSVVLFQQITGQPSVLYYAEQVFIAAGFDASEGAGVSVILGVFKLVMTGFAVKYVDSVGRRPLLLGGVAAMMLATVALGACSDALATGDPADSLNTARLSVLAIFAYVGAYQVSFGPIAWLLVGEIFPQRVRSAAVGTATLTNFASNYLVALYLPTMIASYGQAGTYYIFSVMGVIALASIYLTVPETKGKSLEEIEAEMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N428</accession>
    <name>C1N428_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_9514</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062472.1">
        <property type="nucleotide sequence ID" value="XM_003062426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N428"/>
    <dbReference type="GeneID" id="9688162"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9514"/>
    <dbReference type="eggNOG" id="ENOG502S46H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PQAHSHK"/>
    <dbReference type="OrthoDB" id="1915122at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040153">
        <property type="entry name" value="Rcf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28018">
        <property type="entry name" value="RESPIRATORY SUPERCOMPLEX FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28018:SF3">
        <property type="entry name" value="RESPIRATORY SUPERCOMPLEX FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="HIG1" evidence="5">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="73" mass="7706" checksum="802F81F0967D934B" modified="2009-05-26" version="1" fragment="single">LASIAAWCKEHKLRTIGGVWLGGVAGAFAWNSTRTHLSAAARVFHTRIYAQALTLGCLIGSAAAELYDAKYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N467</accession>
    <name>C1N467_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_52431</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062496.1">
        <property type="nucleotide sequence ID" value="XM_003062450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N467"/>
    <dbReference type="STRING" id="564608.C1N467"/>
    <dbReference type="GeneID" id="9688177"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52431"/>
    <dbReference type="eggNOG" id="KOG0043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IYGREYN"/>
    <dbReference type="OrthoDB" id="10255210at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.170:FF:000004">
        <property type="entry name" value="EF-hand domain containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.170">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006602">
        <property type="entry name" value="DM10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040193">
        <property type="entry name" value="EFHC1/EFHC2/EFHB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086">
        <property type="entry name" value="EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086:SF9">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06565">
        <property type="entry name" value="DM10_dom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00676">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51336">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DM10" evidence="8">
        <location>
            <begin position="56"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="DM10" evidence="8">
        <location>
            <begin position="239"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="DM10" evidence="8">
        <location>
            <begin position="414"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="522" mass="56252" checksum="69F051D332FD1416" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4M4</accession>
    <name>C1N4M4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52612</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063024.1">
        <property type="nucleotide sequence ID" value="XM_003062978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4M4"/>
    <dbReference type="GeneID" id="9688464"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52612"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="682"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="766" mass="81034" checksum="B36C487BFFF8C2EB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N534</accession>
    <name>C1N534_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_52784</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062903.1">
        <property type="nucleotide sequence ID" value="XM_003062857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N534"/>
    <dbReference type="STRING" id="564608.C1N534"/>
    <dbReference type="GeneID" id="9688537"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52784"/>
    <dbReference type="eggNOG" id="KOG0274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LYTKTCG"/>
    <dbReference type="OrthoDB" id="256303at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="133"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="235"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="341"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="510" mass="52530" checksum="3807003BA4C33CF3" modified="2009-05-26" version="1">MDEGFRAMGVGGSREADEDGVDDETVHHRAAPSSGALLRGESAAPTASSFAASRPASVLAANWFESPVSQQGTVTRLSDRPLVCADVDALGAKAYVGGEVSMTAAETASRTDHAVYEVDVKTCKKLRTLYTKTHGHKEWVTKVRCLPDGRVLSSGMDSLICLWDARGTRCSALEGHNGSGAFYTLVPIRSRWRGGRRSLRTFAGVSLRLPLAFNPRPRCLSTPLLTPFNSTLTSLCMERPSVSDVAVGASGLTAVSAGYDKTLKLWNLAPKGFTARSDRCVGTLHGHKAPVTTLAWGERRVAKNAEEKKDQDDASGGLGSGDRDGVVMLWDAGSGAAVGRRGGHRGHVTSLAWIDGGGGGGGAVLLSGGQDGKVHAWDPRVGGTSPVASVAAHVQKAGAGAVGDIVQTVSGAVVTAGADGHVAVIDPRAGFAARGKVACGDFVYSLAAIGPLALAGTGSGGIHVIDIDVTDEPKTLYGLGANEAAVRCVHASEDGLFAAGDDGTCISYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N540</accession>
    <name>C1N540_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52790</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063099.1">
        <property type="nucleotide sequence ID" value="XM_003063053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N540"/>
    <dbReference type="GeneID" id="9688347"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52790"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="97" mass="10352" checksum="DEDBD489A794DD04" modified="2009-05-26" version="1">MEEERERAEKARRREERGGEERGGEERGGERGGDGGAPMEGGLEIRKPPPPPESAAPPESAAAAESAAEVATGARRNKEDAVAAAKARYLERKRKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N567</accession>
    <name>C1N567_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52819</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062919.1">
        <property type="nucleotide sequence ID" value="XM_003062873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N567"/>
    <dbReference type="STRING" id="564608.C1N567"/>
    <dbReference type="GeneID" id="9688554"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52819"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="255" mass="28298" checksum="722B12023058485A" modified="2009-05-26" version="1">MSNESKRRRVDPPAREAPSVDVDDDVSPGDVLRLLLARFEKQEEKLERVGAELTATRRALAELTDVVESMTPTFDVNEQLASVVFSHVNDVRTRVALSQVSSVWRRASKVVSAQPAALEFSPKMLEWYQKGARLGNTECERMLGCLYFLGVGVERNLDTAMQYFEKAAAKGHAAAQNGVGRCHYEKGRYEEAFKWHTKSAAQGYTNAEINLGILYEDGLGVTKDISKAIEWYTKAAEKGVVIAAKCLRKLTQPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N587</accession>
    <name>C1N587_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_52848</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BLOC1S2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C26 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063128.1">
        <property type="nucleotide sequence ID" value="XM_003063082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N587"/>
    <dbReference type="STRING" id="564608.C1N587"/>
    <dbReference type="GeneID" id="9688365"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52848"/>
    <dbReference type="eggNOG" id="KOG3179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92161at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019269">
        <property type="entry name" value="BLOC1_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF5">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10046">
        <property type="entry name" value="BLOC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="4">
        <location>
            <begin position="57"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="330"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="336"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="482" mass="50538" checksum="183DE7A90AC65666" modified="2009-05-26" version="1">MAPRTRFAILDCEDADKWDGHAIAISRLFSRAGERWRVLPAEHFRCFSGELPELASLSSYAGLVVTGSHHGVNDGRGWIDALRSFLAEACDPSRGVRVLGVCFGCQILAQALGGAAGKNPRGDGGFTLKRERVTCHRAMLERDDYQSAAASFPSSSADSDSVIMTVFESHGDAVTSLPPSATTLATSATAPHEIWSRGDNVLAWQGHPELSADAIVAKIVPHVSSLSERQRDAGASSSSHWFPYDRVPVEDFETDDVDGDVARDAMRLIAMGRAFLRGGKCEGDDADVVAAHKYACDERFARCGGGGGGGGGEDDGGLASAAARDFVANFGRKSNAGKEEPGRGRGNERAAASNGRDASTAPPRGPASGDDALKAAAADAFAKTSKHLSAELAIVAAEFRLSADAHDEASRKFDAIASTAEDLRAFAGRLSEKSEKLSPLLRSLRGVDAQVTALEEVAAAMATRASELEAKLVALGGSIAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5K4</accession>
    <name>C1N5K4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Voltage-gated ion channel superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_52954</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063173.1">
        <property type="nucleotide sequence ID" value="XM_003063127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5K4"/>
    <dbReference type="STRING" id="564608.C1N5K4"/>
    <dbReference type="GeneID" id="9688613"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52954"/>
    <dbReference type="eggNOG" id="KOG3713">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YFMLIAN"/>
    <dbReference type="OrthoDB" id="415460at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001508">
        <property type="term" value="P:action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537:SF254">
        <property type="entry name" value="POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="VOLTAGE-GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00169">
        <property type="entry name" value="KCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="323"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="14">
        <location>
            <begin position="109"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="392"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH52309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="493" mass="55151" checksum="436D2D99B8C2F3ED" modified="2009-05-26" version="1">MAAAAASLSTKTMEFKTIREAHEDEARNREHMLQHSFEIRAAIQIQRAWRKYQIHLLAEQGREGGGDVFILVRTNDEPVSFRYHWQLTLYTYFEERGDRPSATTKAVNFVVSVLVIFFIVIATVVFIVETIPTVARDDDAMYALSILEGVCIAMFTLEISVRMSSVPLEDGKYARGLKKWMKNPMNVVDIIAVIPWYLELIVGGGTGAFSVVRVVRLIRVFRVFKINRYNASADLFSRALQRSVQPLTLLFYFMLIANILFSSAIYYAENLGNEHNPSDETNDSIGGPAAPFDSIPRSMYWCAVTMTTVGYGDMFPITLYGRFIAVLTLFAGIIVIAMPITLIGSNFVDEYRKSQMAQWREKKRLEALAKAKEEMKVLPLLTEMGLGSRSRSRSRYDLARKSTEMEGKKKEEGAGGGAGVGTEDVEVLPTAEFAALQPSPWDAPPRPGARLEARTPATGDDAARLARLVIERLDAMQDQIASLEETIVRMTIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5M7</accession>
    <name>C1N5M7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Monovalent Cation:Proton antiporter-2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_22276</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063390.1">
        <property type="nucleotide sequence ID" value="XM_003063344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5M7"/>
    <dbReference type="GeneID" id="9688625"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22276"/>
    <dbReference type="eggNOG" id="KOG1650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WIEHEGA"/>
    <dbReference type="OrthoDB" id="1654420at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045158">
        <property type="entry name" value="KEA4/5/6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16254">
        <property type="entry name" value="POTASSIUM/PROTON ANTIPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16254:SF14">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912312" evidence="11">
        <location>
            <begin position="20"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="12">
        <location>
            <begin position="3"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH52526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="249" mass="26758" checksum="9815851C00DBF132" modified="2009-05-26" version="1" fragment="single">LSFVKVATTLALFLAAATAASKTVVARAFRFISPRGGELYQMVTVAFCLVVAWTSEWLGLSIELGAFVAGVMASATPFTEQTLHAVEPVKNVFTALFLASIGMIMNPYFLWLHLDVLLGTLLVVTVFKCAMMTLVVRSFGYTTRTSLTVGISLAQVGEFSFVLLSRASALGLVQRNMYLLLLGTTALSLIATPLMFRLTPAALKLAHAAKWIEHEGAEEAVEMVGWSEIGAGGPGRSRSRSRSPDPARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5P1</accession>
    <name>C1N5P1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_63729</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063396.1">
        <property type="nucleotide sequence ID" value="XM_003063350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5P1"/>
    <dbReference type="GeneID" id="9688633"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63729"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="452" mass="48705" checksum="9D742EF0E2618537" modified="2009-05-26" version="1">MKLTTFTTDVQVDDVKLMYKVDMSTTTFAEQVALIVNPFSTGVWLLILAVIVTTGISYSAIRGGHEVYDDSKPGDDLKTRAWDTVKSLGAMVFGAVLEFATLEFNVARDGNDNPLTGGRNSSANVIKLALALFTLLTFFIYSAKLTANIVADDSTQTGITSMEQCVAQTCKVCVAEAMEDSAFRIYGGSIQYYPVPMAGEDVARALREEHCDIALLIERIYANEWDAYFGTRSKDDMCQYEFSEVVMPLGVGQPVREEYAEALSYWVNSVADTNGYLSTLMNEYAPLPGCGTIATEDTSSITIEVMTGPALIFFGIVGAIFAYNIIRRRKKLHAAMKIAGSFLTRNKNELTDDDDADDSSVVVTNANNPFLVMAATPAPVQRPSPAARDASASARPSGIDLESCNLIWSTQRKSRGETAGGEAGELAATGESNDGVSASPGSLPPIPSSYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1N647</accession>
    <name>C1N647_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_36384</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ubiquitin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063272.1">
        <property type="nucleotide sequence ID" value="XM_003063226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N647"/>
    <dbReference type="STRING" id="564608.C1N647"/>
    <dbReference type="GeneID" id="9688912"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36384"/>
    <dbReference type="eggNOG" id="KOG0001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CQIPCGI"/>
    <dbReference type="OrthoDB" id="494754at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000016">
        <property type="entry name" value="Polyubiquitin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.400">
        <property type="entry name" value="Nickel-containing superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036502">
        <property type="entry name" value="NiSOD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014123">
        <property type="entry name" value="Superoxide_dismutase_Ni-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09055">
        <property type="entry name" value="Sod_Ni"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109770">
        <property type="entry name" value="Nickel-containing superoxide dismutase, NiSOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="7">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH52408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="205" mass="22841" checksum="D223D7997BE5FD8E" modified="2009-05-26" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGHCQVPCGIFDDPAMIAELKEACATIRKAMAQITELSAAPPSAANFNQMTRWVMTKEEHCGRIIAKVSEYCLCQRVKVELYKDAEEYKEALRLHHELMQAAMKAKQTVDTAGADALEHALSHVAAQYTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N703</accession>
    <name>C1N703_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_3762</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063643.1">
        <property type="nucleotide sequence ID" value="XM_003063597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N703"/>
    <dbReference type="STRING" id="564608.C1N703"/>
    <dbReference type="GeneID" id="9689263"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3762"/>
    <dbReference type="eggNOG" id="ENOG502QQQ2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WDNYNAC"/>
    <dbReference type="OrthoDB" id="1461976at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fatty acid desaturase" evidence="1">
        <location>
            <begin position="58"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="312" mass="35314" checksum="C0F573FB1C325160" modified="2009-05-26" version="1" fragment="single">DDDDDKTGVVPSLRELRAAIPAECFVPCLRESMKYAAIDLGLLAACFGLWSPLVVDNPWMLPLYAPVTGTIMWMCFVVGHDCGHGSFSENKWINGVVGHATHSPLLVPFYPWAYSHKQHHRFHNHEEKDMSHPWMSAERYKDTNAIVRFLALDHPWGAFLGFPGYLLLEPKWSSTDGSHFNPAGRLFDRAPKDERLKCAVSTVACAAFLLATFAACDGPAQWATQYLAPYLCFSWWLFTVTYLQHHDHDTKTYKEGEWEYVLGGLETIDREFGYGVDEATHHITDCHVAHHMFSDMPHYNLEKATAGVRGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N758</accession>
    <name>C1N758_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_65886</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063676.1">
        <property type="nucleotide sequence ID" value="XM_003063630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N758"/>
    <dbReference type="GeneID" id="9689285"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65886"/>
    <dbReference type="eggNOG" id="ENOG502S5DF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CARICDF"/>
    <dbReference type="OrthoDB" id="498642at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="5">
        <location>
            <begin position="60"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="246"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="274" mass="29208" checksum="7073876FAC95AC03" modified="2009-05-26" version="1">MAPAAANEESPYLRHWSRVYAEDPSARTREWHCAFDDAVDVLRPYVAPIVASSPSRSLVVDVGCGGSSIGYDLAKAFAFTDVLMTDIDPGIVEILRERYASSSSSSSSSSSAAAAPATRCEVADARSMPTVPTGAAVVVLDKGTVDALHGDDDKLATLRECVRMANRPDGVGVVASISFPAADRLRLLERVARETRVGLRVRVVGDGDPARGRRAVFVAVLGKRVERVETPRCELSETVLARIRRSGSVVEDEPAGEEDALTLFDDSDGDGDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7H3</accession>
    <name>C1N7H3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_43102</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063898.1">
        <property type="nucleotide sequence ID" value="XM_003063852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7H3"/>
    <dbReference type="GeneID" id="9689178"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43102"/>
    <dbReference type="eggNOG" id="ENOG502SHXE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FPIGRYW"/>
    <dbReference type="OrthoDB" id="568060at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22786">
        <property type="entry name" value="DPBB_YuiC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010611">
        <property type="entry name" value="3D_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051933">
        <property type="entry name" value="Resuscitation_pf_RpfB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39160">
        <property type="entry name" value="CELL WALL-BINDING PROTEIN YOCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39160:SF4">
        <property type="entry name" value="RESUSCITATION-PROMOTING FACTOR RPFB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06725">
        <property type="entry name" value="3D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="3D" evidence="3">
        <location>
            <begin position="181"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="247" mass="26312" checksum="D83B6C79259A6A1D" modified="2009-05-26" version="1">MPPAPYTRTMEATAYSSDWRSCGWTWGLSLGPLPFYVPLCLGTRPSGTREWPLVPRPRRDVADAKADLALGGLALACLTALSVASGALLDGSFLRRRAAIAARGRVARAAALGAGVGATAFPIGRYWAETDLAGLPYSGATASGKQPRAMRPPITRVNPLTDPIAFASRVLTLQWGPVDGSIAADTSVYPFGTRMKIEGMGWGVVEDRGGGVVGGDRIDIYVRRRKRALEFGRKRVEVTVHPPPAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7U2</accession>
    <name>C1N7U2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_30126</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I NDUFA5 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064150.1">
        <property type="nucleotide sequence ID" value="XM_003064104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7U2"/>
    <dbReference type="STRING" id="564608.C1N7U2"/>
    <dbReference type="GeneID" id="9689411"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30126"/>
    <dbReference type="eggNOG" id="KOG3365">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ENQWKWP"/>
    <dbReference type="OrthoDB" id="286811at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006806">
        <property type="entry name" value="NDUFA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04716">
        <property type="entry name" value="ETC_C1_NDUFA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="130" mass="14430" checksum="1A06CA409E805AE2" modified="2009-05-26" version="1">MSHFFIRQSRALLGAVKQTTGIVGLEPIADGRGALGAIVARVLTEVKTQIPEEAGYRKVVESVYRHRQKIIEEVEDPAQIEARIGCGQIEELVAQAKDELRLIPKMAETKPWEFDHAIKSIAPQGKTLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7U3</accession>
    <name>C1N7U3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosome assembly factor mrt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_30129</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Ribosomal protein P0 is the functional equivalent of E.coli protein L10.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">Associates with the pre-60S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
            <location evidence="7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063970.1">
        <property type="nucleotide sequence ID" value="XM_003063924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7U3"/>
    <dbReference type="STRING" id="564608.C1N7U3"/>
    <dbReference type="GeneID" id="9689592"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30129"/>
    <dbReference type="eggNOG" id="KOG0816">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LEWAENY"/>
    <dbReference type="OrthoDB" id="10262308at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05796">
        <property type="entry name" value="Ribosomal_P0_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1730:FF:000005">
        <property type="entry name" value="Ribosome assembly factor mrt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000003">
        <property type="entry name" value="Ribosome assembly factor mrt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033867">
        <property type="entry name" value="Mrt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051742">
        <property type="entry name" value="Ribosome_Assembly_uL10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841:SF1">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 MRTO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="9">
        <location>
            <begin position="126"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="258"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH51592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="291" mass="32355" checksum="1BFD0EA1D88FD6FF" modified="2009-05-26" version="1">MPKSRRDKVIALTQTKKKGREWKSGLIDTVREALDEYDSVYAFRTENLRNNTFKELKSDLAESSRFFMGSNKVLQVALGKGPEDEQREGLHQLSAHVRGHAGIVMTNLRKEDLEKALEKYKVSDYARTGSLAPETIVIEEGPVHGPHGGLMEHTMEPTLRKNGMPTKLNRGVIELLADHVVCREGEHVSPQAAILLRLFGHELATFSIDLLCGWREGGEFEEYDAALEGDDDDDDVDIGDVERDRFAFDNVSKSMMLPPELMNAVPGQPLGGGDAPAKKRTSTRKKAGTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8L9</accession>
    <name>C1N8L9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WAT1-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_54139</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064289.1">
        <property type="nucleotide sequence ID" value="XM_003064243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8L9"/>
    <dbReference type="GeneID" id="9689730"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54139"/>
    <dbReference type="OMA" id="PVMIKYP"/>
    <dbReference type="OrthoDB" id="498093at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030184">
        <property type="entry name" value="WAT1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31218">
        <property type="entry name" value="WAT1-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="8">
        <location>
            <begin position="41"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="362" mass="38710" checksum="0A1250BA324E8587" modified="2009-05-26" version="1">MAPPGGGGTFAPAVRAASRALLDWSLAQYARPSNAFCHGALVLAQLLFAGMHITAASALDHIPPFSFCALRLALALPFLYWLARREGGRALRGWERAWPLPMGAAIGTAYALVFVCNQRSGPNYTAMVQPLIPLAAAAMSAALRIERVDAMKAGGLFVSVVGTTITLRVWTNEDEAPGVVDSIFLMTQPIAYATYVVLLALALKRVRAGDGSNSTAAVTRRSVTTSHFEDEDDDDDDDVVIEGLDRPPPGPMLFLFAATVVSEIVIASVGVRGLVRRVEWSTLPAHAYLAVLYAGIMSSCFAHGINSWAISHVSGVLPTVYSGVQVIFTVILADIFLDEGAFYKIVSDWSPYDRVGEVDAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8Q9</accession>
    <name>C1N8Q9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43396</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP15 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064318.1">
        <property type="nucleotide sequence ID" value="XM_003064272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8Q9"/>
    <dbReference type="STRING" id="564608.C1N8Q9"/>
    <dbReference type="GeneID" id="9689931"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43396"/>
    <dbReference type="eggNOG" id="KOG2974">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RGHVKPQ"/>
    <dbReference type="OrthoDB" id="20949at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012459">
        <property type="entry name" value="Rrp15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245:SF14">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07890">
        <property type="entry name" value="Rrp15p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="365" mass="39175" checksum="E7B4741030E05357" modified="2009-05-26" version="1">MGALGKRKPAAGKKPSAKAAKREPSPEPASESESEDGSSGDDDDEDEAGGGAEESNSGDGSDSEEALGEDDASDDDDDDDDDDDASADDLDDEAFEGDDVDLDDDDDEDEGEEEEEDDDAEDSDGAMDDDFDGDDAGEAAGSDSEDSRQEEYDDAARAAAAAASRAGGGGGFGFAKAFANLVGDDPSREAEVLPKTKKQRRVEAEARREKRARNAEKSRKLELRERGHVVPKKGVADPASDQLERRLIQTATRGVVRLFNAVSKAQRDAAEADASRDKKKKKTTLLSSKGFMAELTKRTKARTDDEIEMEAEILKKTAGQKKAEAEGGWDVLSDGYLMGRNKMKDWEKGTAAGENELEIEDEMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8X6</accession>
    <name>C1N8X6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_23556</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064354.1">
        <property type="nucleotide sequence ID" value="XM_003064308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8X6"/>
    <dbReference type="STRING" id="564608.C1N8X6"/>
    <dbReference type="GeneID" id="9689962"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23556"/>
    <dbReference type="eggNOG" id="KOG2704">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WHGTRPG"/>
    <dbReference type="OrthoDB" id="286734at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049941">
        <property type="entry name" value="LPLAT_7/PORCN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906:SF4">
        <property type="entry name" value="LYSOPHOSPHOLIPID ACYLTRANSFERASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906">
        <property type="entry name" value="PORCUPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="497" mass="54925" checksum="6675064EC4F936AE" modified="2009-05-26" version="1">MEWEWQRAVCRPLSGPLGVPPGTVLFTLALFASLPIGAGFRFIESPVLKNLYGLLAGTFLSVFAFGSATASVFVFGAASYAAMAAHRKRCGAIVGVGAFAYLIYFHATSSSGEAWKAGNIDITGLLMVLTLKVTACALNYQDAAAPLDRLSDFQKRRAVTTLPNPLDYAAWLVFPCTLVVGPALEFRDYSDWLRGKGVWDKNHRNGGCPSVFVQAMKTAAYATFFMTIHLYVATIYTIDDTYLSPDWNSKPLWLKFWELHILGQGSRGKYFFCWVWAEAACVASGIGFSGHEEKKGAGEVATTRVATWETGKNVRPMGVETAATFVQIPHHWNIQTGKWLRHYVYDRSTPAGKKPGFRQLLLTQTVSGVWHGLYAGYWLFFVSSAVFIEGSKSVYRWQSKHWLFSRAPASWLISLPHWLLATVGLNYLCGAFMLVTFRQCVDAWASVYFLPHLIIVAMVIFGRVVNPKKKRDRGDASAKANASGTVGVGAEEKKKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N912</accession>
    <name>C1N912_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_9952</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064535.1">
        <property type="nucleotide sequence ID" value="XM_003064489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N912"/>
    <dbReference type="STRING" id="564608.C1N912"/>
    <dbReference type="GeneID" id="9689976"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9952"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RREAMRW"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF10">
        <property type="entry name" value="MRJ, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="2"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="54" mass="6263" checksum="7DF1429080211769" modified="2009-05-26" version="1" fragment="single">IDYYALLGVKPGASADELKKAYRREAMRWHPDRHPEGEAKRAAEKKFKQVSEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9B7</accession>
    <name>C1N9B7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54438</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064427.1">
        <property type="nucleotide sequence ID" value="XM_003064381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9B7"/>
    <dbReference type="GeneID" id="9689868"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54438"/>
    <dbReference type="OrthoDB" id="502714at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="217" mass="24022" checksum="CBF3D962FBF51E88" modified="2009-05-26" version="1">MDDYPQLWPAEDDAVDGTEDLNAEEAARSVHWFPYDPKRTERRELAAEVFVLAKGVFFVVPALTLGFSWVLGAVFAEIEGWSNENGFYYVVSMLFGLPDPITDPPELSPTTTNGKICDVFIALLAWSLIGTFVGIIVNLNVISRFVGWLESGGSRWRRLFNVKTLGDFEGDALREVDDARTMREAARTFGEINAEMASARAELLGLIAPEGTPKNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9D0</accession>
    <name>C1N9D0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_30402</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064596.1">
        <property type="nucleotide sequence ID" value="XM_003064550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9D0"/>
    <dbReference type="STRING" id="564608.C1N9D0"/>
    <dbReference type="GeneID" id="9689874"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30402"/>
    <dbReference type="eggNOG" id="KOG0767">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KMYIEEG"/>
    <dbReference type="OrthoDB" id="427452at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF12">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="12"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="109"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="210"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH51501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="312" mass="32639" checksum="77DC2252952F8A8E" modified="2009-05-26" version="1">MAASGKAEYGLDYFLKGALAGGICCSITHGALTPVDVVKTRMQLEPTKYTGMISGFNKVIAEEGAGALLTGLGPTAFGYFVQGWFKFGGVEYFKIQAAQSMTEQQTWDNRNSIYLGASAAAEFIADIFLCPLEATRIRLVSNPTYADSMLGCMAKMVKEEGVIGAFYSGFGPILAKQVPYTMAKFAVQGATAEKIYDSLGKTPKEMSSGENISVSLASGVVAGVTAAIISHPADTLLSKINKAGAGGSGGMFSRLANIAAETGLVKLCTQGLAARCVMIGTLTAGQFGIFDIVMNAVGASKFHFHDPSKGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA80</accession>
    <name>C1NA80_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54795</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064860.1">
        <property type="nucleotide sequence ID" value="XM_003064814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA80"/>
    <dbReference type="GeneID" id="9690187"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54795"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="255" mass="26822" checksum="D00FADA3552A535F" modified="2009-05-26" version="1">MSASASSALASSLSRAPALSSRAAARGRVVGRAAAAAARRQRHRGRRPSSSSPRLVLRVVSYVQYTLDGPGCAASRSEADWHTSVLLGSHPEGCPPHPVDVTERCEAGDGAFALGNARFEQRGEDLYLSVVDAASEEEEEEGTTIRAESEGAGGEYVAGESKELEREREFDDERKGGVGGGGFYAGAFFGSSFGFPFFLSPLTSLVVHSRAAVRVDGKAVGRESVKLSPGAIVTLEKPGSETATFEVNRQVHAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGF1</accession>
    <name>C1MGF1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_13366</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054762.1">
        <property type="nucleotide sequence ID" value="XM_003054716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGF1"/>
    <dbReference type="STRING" id="564608.C1MGF1"/>
    <dbReference type="GeneID" id="9680894"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13366"/>
    <dbReference type="OMA" id="MSTYDES"/>
    <dbReference type="OrthoDB" id="10259892at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043043">
        <property type="term" value="P:peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000004">
        <property type="entry name" value="Elongation factor P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="ELONGATION FACTOR P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053:SF14">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR KOW-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation elongation factor P/YeiP central" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Elongation factor P C-terminal" evidence="1">
        <location>
            <begin position="60"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="124" mass="13443" checksum="DCF1A86C8B45BC1F" modified="2009-05-26" version="1" fragment="single">QYMYDAGDDALILSHPTTFEQLEVSGETFGAQRRFLADGAFVDVLSHDGEVVGVQLPDEIRATVVETDPRFKGESKDGGRLKPCTLDTGATTRVPTYVEAGDVVVVKGPRTGALGEFVRRVRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGI3</accession>
    <name>C1MGI3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_46096</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055327.1">
        <property type="nucleotide sequence ID" value="XM_003055281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGI3"/>
    <dbReference type="STRING" id="564608.C1MGI3"/>
    <dbReference type="GeneID" id="9680893"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46096"/>
    <dbReference type="eggNOG" id="KOG0161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ERRYFAD"/>
    <dbReference type="OrthoDB" id="551249at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870:SF9">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="348"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="591"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="804"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="91"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="863"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="958"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1078"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="370"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="804"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1161" mass="124913" checksum="0CCE8C897860D417" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGJ4</accession>
    <name>C1MGJ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_13559</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055332.1">
        <property type="nucleotide sequence ID" value="XM_003055286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGJ4"/>
    <dbReference type="STRING" id="564608.C1MGJ4"/>
    <dbReference type="GeneID" id="9680293"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13559"/>
    <dbReference type="eggNOG" id="KOG3627">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WGFRIAD"/>
    <dbReference type="OrthoDB" id="512168at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="214" mass="22279" checksum="CEF22B4A2C9A30C1" modified="2009-05-26" version="1" fragment="single">CGGSLVAPNKVLTAAHCEITTYASAGEGTIAYVNFHDRTGVAHDATQALATTENVGVASVVNHPQYDSNTVNYDFAILTLPSDSQYTPVVLDFDDANVAESGENLRVMGFGTTTQYQSGSTPSPNPTSAKLLEVTVPGMAYATCVNTYGGLVRDTMLCAGASGLDACQGDSGGPLIRVSDSKQVGVVSYGYGCAWPNNPGVYARVTAVKSWMCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGN2</accession>
    <name>C1MGN2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_49876</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Choline transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055349.1">
        <property type="nucleotide sequence ID" value="XM_003055303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGN2"/>
    <dbReference type="GeneID" id="9681102"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49876"/>
    <dbReference type="eggNOG" id="KOG1362">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ITGEAFC"/>
    <dbReference type="OrthoDB" id="420519at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF98">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="556" mass="58652" checksum="87478A1D09F3380C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGX3</accession>
    <name>C1MGX3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_49971</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054852.1">
        <property type="nucleotide sequence ID" value="XM_003054806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGX3"/>
    <dbReference type="GeneID" id="9680261"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49971"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="50" mass="5873" checksum="CF4A2BD2096CE4AA" modified="2009-05-26" version="1">MADTARRCRTYCRWLAMIVVAYMSWRHRADILGTMRDAGVLPKAWVEEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH20</accession>
    <name>C1MH20_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">P-type ATPase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_50020</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055417.1">
        <property type="nucleotide sequence ID" value="XM_003055371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH20"/>
    <dbReference type="STRING" id="564608.C1MH20"/>
    <dbReference type="GeneID" id="9680507"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50020"/>
    <dbReference type="eggNOG" id="KOG0202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PLWNNMM"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000055">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000003">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000065">
        <property type="entry name" value="Sarcoplasmic/endoplasmic reticulum calcium ATPase 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="290"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="794"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="827"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="867"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="963"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="11">
        <location>
            <begin position="3"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH60669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1015" mass="107983" checksum="2C46EC4A87519846" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHD9</accession>
    <name>C1MHD9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50142</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055473.1">
        <property type="nucleotide sequence ID" value="XM_003055427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHD9"/>
    <dbReference type="GeneID" id="9681090"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50142"/>
    <dbReference type="OMA" id="WCSERER"/>
    <dbReference type="OrthoDB" id="10688988at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="699" mass="72913" checksum="78826D7E2B989B49" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHH8</accession>
    <name>C1MHH8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50203</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054955.1">
        <property type="nucleotide sequence ID" value="XM_003054909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHH8"/>
    <dbReference type="STRING" id="564608.C1MHH8"/>
    <dbReference type="GeneID" id="9680685"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50203"/>
    <dbReference type="eggNOG" id="KOG0147">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1906">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FPGCSCK"/>
    <dbReference type="OrthoDB" id="423462at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12285">
        <property type="entry name" value="RRM3_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="2">
        <location>
            <begin position="351"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="680"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="811" mass="87818" checksum="DF03D7AF1A6FA864" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHY5</accession>
    <name>C1MHY5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_12743</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055571.1">
        <property type="nucleotide sequence ID" value="XM_003055525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHY5"/>
    <dbReference type="STRING" id="564608.C1MHY5"/>
    <dbReference type="GeneID" id="9680993"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12743"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WGRCGIE"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="349" mass="36917" checksum="D2599989312AF932" modified="2009-05-26" version="1">MAGSVAAAARSLTRASVPRPSRRLTTSSASAESSSDAGRAFGTTKRQKIALVTGSTDGIGLHTASLLAASGHGVIVHGRSSERVDAACERVNAVAGDSGGGVVGSYVRDFDSLQDARDLAAEVLERHASLDLLDNNAGVFEPKRHVTADGHERTFQVNVLTPYLLTGLLLPRLVETAAASGASGGGGGGGAADVRILNVASISQTSKIDFDNLECEKSFSNHASYCHSKTMMKLFSFEMYERVAAAAAKGGEPSPLRDVAVLACDPGTVNTKMLLAGWGPCGIETFEANDQFELLTRERFGNASVPESERGGYYVNRTLRETPGGVELEDRKRLWEILERETGVTYPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI53</accession>
    <name>C1MI53_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50441</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055070.1">
        <property type="nucleotide sequence ID" value="XM_003055024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI53"/>
    <dbReference type="STRING" id="564608.C1MI53"/>
    <dbReference type="GeneID" id="9681174"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50441"/>
    <dbReference type="eggNOG" id="KOG2948">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FHCDEVV"/>
    <dbReference type="OrthoDB" id="10265310at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="MYG1_exonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215">
        <property type="entry name" value="METAL DEPENDENT HYDROLASE - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215:SF1">
        <property type="entry name" value="MYG1 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="MYG1_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="330" mass="36560" checksum="B0DC68A0F4E87FCD" modified="2009-05-26" version="1">MSTKRMAPTKIGTHDGSFHCDEALGCHLLRLTKAYADATIVRTRDQDLLSECDIVIDVGATYEPEKFRFDHHQKGFEEVFGHGHTTKLSSAGLVYKHFGREIVANVLKKDAADPIVEKIYLKVYKSFVECVDGVDNGVQIFESDKPALYVDNTGLSARVGKFNANWNEPFTDETQMAGFEKAMALAGGEFEDAVRYYGEVWHPARAHVIDALDAASATHASGEILKLETFCPWKEHLFELEEERGMTTLPKYVLYDDGKGSWRVQAIPETPSSFNSRRGLPKAWRGVRDDALSELSGIEGCIFVHAAGFIGGNKTYDGALAMASKALELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ51</accession>
    <name>C1MJ51_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50813</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055252.1">
        <property type="nucleotide sequence ID" value="XM_003055206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ51"/>
    <dbReference type="GeneID" id="9680890"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50813"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="62" mass="7079" checksum="BD1AC30AA3BC35E9" modified="2009-05-26" version="1">MAARREAWRADVDAAREAHEEGRRRMCAATEARREGVKDALQKRLSQRKLAKENSVKENAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJI7</accession>
    <name>C1MJI7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55839</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH60007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056631.1">
        <property type="nucleotide sequence ID" value="XM_003056585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJI7"/>
    <dbReference type="GeneID" id="9681618"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55839"/>
    <dbReference type="eggNOG" id="ENOG502SCHQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TVAFAYR"/>
    <dbReference type="OrthoDB" id="250548at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019351">
        <property type="entry name" value="DUF2039"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22876:SF5">
        <property type="entry name" value="CHROMOSOME 9 OPEN READING FRAME 85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22876">
        <property type="entry name" value="ZGC:101016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10217">
        <property type="entry name" value="DUF2039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="165" mass="18542" checksum="AB8034D73D23D079" modified="2009-05-26" version="1">MASSGGGGIPNERHAGQRVKPGQKYQNREGFKAHRNMKRAVRDVDAENDLRHRACQGVCRRCAQKAREAVPSESRVVQWRFQYQKYRALRPGKHGKCHACERAVHFSYRNLCQTCATTKKLCPGCSKPPAESQLARPDELSDGGDDGEDESTDDDEYEGVVITRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJI8</accession>
    <name>C1MJI8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54974</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055829.1">
        <property type="nucleotide sequence ID" value="XM_003055783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJI8"/>
    <dbReference type="STRING" id="564608.C1MJI8"/>
    <dbReference type="GeneID" id="9682071"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54974"/>
    <dbReference type="eggNOG" id="KOG2977">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RWIHADG"/>
    <dbReference type="OrthoDB" id="3784at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859:SF91">
        <property type="entry name" value="DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859">
        <property type="entry name" value="GLYCOSYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="2">
        <location>
            <begin position="36"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="301" mass="33303" checksum="86E8714DD39F5BA3" modified="2009-05-26" version="1">MSSTRRSPRVGDAAAARASSRPSTSGPSTPPDVALVVPCHDEAKRLDVDAFVAFARASTRESPCVVVFVDDGSGDDTLAVLREIRDRAPAGAVEILADRANVGKAEAVRRGLRFAIERLRASHVAFWDADLATPLDHVRLFRDVFETRPEIDIVFGARVGLLGRDISRSMTRHYMGRVFATLASWTLSLSVYDTQCGAKMFKVVGGGTSELAVVLSEPFRTRWVFDVEMLARFHALAVADGSAPVRERVYEFPLLRWKDVGGSKVKASDVVKMAWGLLGIRRRYFWSREPWPPPRRDDDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJN8</accession>
    <name>C1MJN8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55036</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056245.1">
        <property type="nucleotide sequence ID" value="XM_003056199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJN8"/>
    <dbReference type="GeneID" id="9681630"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55036"/>
    <dbReference type="eggNOG" id="ENOG502S861">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="194076at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050744">
        <property type="entry name" value="AI-2_Isomerase_LsrG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33336:SF1">
        <property type="entry name" value="(4S)-4-HYDROXY-5-PHOSPHONOOXYPENTANE-2,3-DIONE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33336">
        <property type="entry name" value="QUINOL MONOOXYGENASE YGIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="2">
        <location>
            <begin position="5"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="161" mass="17740" checksum="42264290B65DCF14" modified="2009-05-26" version="1">MDQMRVTTVDVACVPGTEAAFAAASIANARSSVEEEDNARFDVLQDVGDDAKFVLVEIYDSPEGVAAHKETAHYARWRDDVADAMAVPRRAGKYVPVYPWRGLWGSGAAARRKASARSTPEEASFLKPRRDDGASDENEDEVRSISHWSPYDRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJQ9</accession>
    <name>C1MJQ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_55060</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055863.1">
        <property type="nucleotide sequence ID" value="XM_003055817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJQ9"/>
    <dbReference type="STRING" id="564608.C1MJQ9"/>
    <dbReference type="GeneID" id="9681425"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55060"/>
    <dbReference type="eggNOG" id="KOG2391">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CELDAND"/>
    <dbReference type="OrthoDB" id="306304at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008333">
        <property type="term" value="P:endosome to lysosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11685">
        <property type="entry name" value="UEV_TSG101-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052070">
        <property type="entry name" value="ESCRT-I_UEV_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017916">
        <property type="entry name" value="SB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008883">
        <property type="entry name" value="UEV_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306:SF3">
        <property type="entry name" value="TUMOR SUPPRESSOR PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306">
        <property type="entry name" value="TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05743">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09454">
        <property type="entry name" value="Vps23_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51322">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="UEV" evidence="9">
        <location>
            <begin position="64"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="207"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="358"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="316"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="219"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="365"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="620" mass="66380" checksum="EF0B0E16BD49E3A0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK24</accession>
    <name>C1MK24_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_24681</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055917.1">
        <property type="nucleotide sequence ID" value="XM_003055871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK24"/>
    <dbReference type="STRING" id="564608.C1MK24"/>
    <dbReference type="GeneID" id="9681916"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_24681"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YKMSVPK"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000016">
        <property type="entry name" value="Solute carrier family 25 member 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="80"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="181"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="283"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH59293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="393" mass="41525" checksum="391D3004F7D6431B" modified="2009-05-26" version="1" fragment="single">MEGGAYAQGDQTTELEFESAMTFASARGFELGRVAARDRAPSRSAAAFDRSSSARCCSTAHASRPFAAASASNDRNVGVWSVCKSLLAGGVAGGVSRTAVAPLERLKILQQVAGSTTKSYKGVLGGLSHILRTEGVLGMFKGNGANCVRIVPNSASKFLAYEFLEGFLVKRARESDENAQLGPVTRLIAGAGAGVFAMSATYPLDMVRGRLTVQVDGKGMKQYTGMMHATRVIVREEGARALYKGWLPSVIGVIPYVGLNFAVYGTLKDYAADFQGLDSAKDLSVASGLACGGVAGAIGQTVAYPFDVCRRKLQVAGWEGAKALAEGEHARRLSNVRYTGMIDCFVKTVKNEGVGALFHGLSANYVKVAPSIAIAFVTYEELKKLLGVELYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKG3</accession>
    <name>C1MKG3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_64393</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056378.1">
        <property type="nucleotide sequence ID" value="XM_003056332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKG3"/>
    <dbReference type="STRING" id="564608.C1MKG3"/>
    <dbReference type="GeneID" id="9681498"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64393"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TAGANCK"/>
    <dbReference type="OrthoDB" id="421993at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF7">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="67"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="269" mass="28044" checksum="6ECE95EC70C7D5F1" modified="2009-05-26" version="1">MSSLSWMSSSGLSTSVHGLQRARSSAPSRNKTSSVHEQNPCSCCLHSLSLVRRMGTMIRKQNVSVKEIVHAYVEKILATDTTTQSFTSLTADSALQQAEYLDSLFASGLDPGPLAGVPFAIKDNICYSGSATTAGSKLLEKHQPAYDAHVLSALRASGALIIGKTNMDEFGMGSTTENSAFQLTLNPWDLTKVPGGSSGGSAAAVVMQQCALALGSDTGGSIRQPASFCGVVGLKPTYGLLSRHGLIAYASSFDSIGPLSSSVEVSALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKK8</accession>
    <name>C1MKK8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_38453</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056013.1">
        <property type="nucleotide sequence ID" value="XM_003055967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKK8"/>
    <dbReference type="GeneID" id="9681509"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38453"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="197" mass="19376" checksum="F10A4BE417E50EFF" modified="2009-05-26" version="1">MALGTLVAAYAKRGGRPPTRRAALAAIAALAVVEFTWLMRRRADDRVVADADAARVAGAPSRAGAARAVGAAGKAGAMTRDGGGDRCGRAGGAGGASGCDSSSSSSSSNATDGAGKRRRGSDRASVASSPPRAFASASDAIVDWWAGEGGKHPLSVSSPAAAAVGLAGCCGGQRAPSSRLATSSRVHRSVVVESRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKQ4</accession>
    <name>C1MKQ4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LHCP1</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_45265</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056426.1">
        <property type="nucleotide sequence ID" value="XM_003056380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKQ4"/>
    <dbReference type="STRING" id="564608.C1MKQ4"/>
    <dbReference type="GeneID" id="9681356"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45265"/>
    <dbReference type="OMA" id="HVADPIH"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="257" mass="27189" checksum="7A1E5D15EA72F6B4" modified="2009-05-26" version="1">MSTNALSSSFSGVRVTSGESLKGSRDRTVLVVQARRTKASAPSRSAAKVAKFGSTAPPDLYPEFGVYPGGGESPIIPFDDDKNAEREIIHGRWAMLGVTGAWAAENGTGIPWFTAGTLCTPDDCTAVADKFPGAVAPLAPEGSGYPSFWAVLSIEVFLVGSAECYRTGLFENPFPELELSVTPGGRFDPLGFAEAGDLEELKVKELKHCRLSMFAWLGCIAQALATQEGPIANWQAHVADPVHANVLSNAASGFGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKV1</accession>
    <name>C1MKV1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_70277</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056059.1">
        <property type="nucleotide sequence ID" value="XM_003056013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKV1"/>
    <dbReference type="GeneID" id="9681983"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70277"/>
    <dbReference type="OMA" id="GINMWIM"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033579">
        <property type="entry name" value="TMEM128"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31134">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31134:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20479">
        <property type="entry name" value="TMEM128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="21270" checksum="08A10D8763EF3C07" modified="2009-05-26" version="1">MHPTLKKYPDEILEAQDEVTLKAGENFDCIALVQQRARRRHQLRAKVERVVWILTSFCIIYYGDGSVDLVTASTSQSGVLWSWYVLAFLPLGINMWIMCHLVRRHQLQHRGSNWSRKAPWALPASSICGIISFIGFAKLFWHVYGWITPFVEVFLCIGFLMITCFFPDVCFSVTKGDHLKKWNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKW5</accession>
    <name>C1MKW5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55482</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056067.1">
        <property type="nucleotide sequence ID" value="XM_003056021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKW5"/>
    <dbReference type="GeneID" id="9681737"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55482"/>
    <dbReference type="OMA" id="PNISICG"/>
    <dbReference type="OrthoDB" id="10499902at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="245" mass="27947" checksum="04EED7D3A2D0EFD1" modified="2009-05-26" version="1">MYRCVEVLSRTTLTGCCGECIKLRGQPVFMYGTLFICFEYALFCVICVGGVYKSPPNISICGYLELLPNWVAFLYFQVASSGIDSTLWHAAITLKQEPRPFLAILQCALGLSCATTLFGFSILPRCLWDWHQACVLAWVSLTSAAMSINIARDYRNLDYTAFPAALWILGIFFCNFFYHESTLRFFFAEALSVISYILWCSSNHRQLDREFTIFHVLIIDGFLATIFLGLFRYHQRVACVVTGKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM45</accession>
    <name>C1MM45_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_32389</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM120 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056872.1">
        <property type="nucleotide sequence ID" value="XM_003056826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM45"/>
    <dbReference type="GeneID" id="9682773"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32389"/>
    <dbReference type="eggNOG" id="KOG4758">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YTRVAMG"/>
    <dbReference type="OrthoDB" id="2015098at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012926">
        <property type="entry name" value="TMEM120A/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21433:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 120 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21433">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07851">
        <property type="entry name" value="TMEM120A-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="405" mass="45079" checksum="C93D1C9A85323626" modified="2009-05-26" version="1">MSDPTLANTAENADEVISEEVAVANEAKDLEKRIHTISGRVAQLDMNLRTCCDDLTTMSESVMRLKKRASRLPPGSEERKQSEQSLYQAQLVMKGAGPAGALDGYLKPRPNSKFLKLFLGAAVDVTSQRQENRLKIKEEYYEFRDKSTYAYIFWPCALLYLNQQRKKLASEPQQNGGGAFSLATAFPALVQAYWVWMLYFYAALALRENVLRANGSHIRAWWVNHHYYSIGMCLVVLTMDVQSNACLDYMTRFLAFTALQGAVMLAQNRYQRFRLYTRVAMGKANPMDVAGGEMGGNTGQLKLLYPLLFGLQMTQIYFGAVVLKAVAVEHGMDAFGSGGFGGGDKSGAGRRGKGDVAGPTEFDFFKDWQAPACGLLFIVMGVGNFRATLQTWLTKRSYASRAKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMQ6</accession>
    <name>C1MMQ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_25907</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057446.1">
        <property type="nucleotide sequence ID" value="XM_003057400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMQ6"/>
    <dbReference type="STRING" id="564608.C1MMQ6"/>
    <dbReference type="GeneID" id="9682410"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25907"/>
    <dbReference type="eggNOG" id="KOG1320">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HCEPNYS"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000012">
        <property type="entry name" value="protease Do-like 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041517">
        <property type="entry name" value="DEGP_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046449">
        <property type="entry name" value="DEGP_PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45980:SF18">
        <property type="entry name" value="PROTEASE DO-LIKE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17815">
        <property type="entry name" value="PDZ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="226"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Protease Do-like PDZ" evidence="6">
        <location>
            <begin position="316"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="463" mass="50514" checksum="702BC0C14354C977" modified="2009-05-26" version="1">MDAVVKVFCTHTEPNYSLPWQRKRQSASTSSGFIIRGRRILTNAHSVEHHTSVKLKKRGGDKKYEARVLAIGVECDLALLTVDDDEFFAGTTPIDFGQLPSLQAAVTVVGYPIGGVAISVTSGVVSRIEVTSYSHGSSELLGLQIDAAINSGNSGGPAFNAQGGCVGVAFQSLKADDAENIGYVIPTPVIMHFIRDYEKNGKYTGFPTLPATWQKLENPNMRKFLKMTPAQKGVMVRRVDPVSPGSNKLKNGDVLLSFDGVEIANDGTVPFRTGERISFHYLVTEKFVGEKARVTFLRDGTTHAVDLPLTQVPRLVPVHIEGVPPSFYIAAGLVFTTVCVPYLKSEYGKDYDYDAPVPILNRMMYDQVTDKGQNVVVVAHVLSAPINIGYEDIVNTVVNGFNGKPVSNLKQLADMCDGCKDPFMRFELDHNLLVVLKTKEAHGATQDILKTHCIPSAKSQDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMR6</accession>
    <name>C1MMR6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56628</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056974.1">
        <property type="nucleotide sequence ID" value="XM_003056928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMR6"/>
    <dbReference type="GeneID" id="9682892"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56628"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="AntiFam" id="ANF00011">
        <property type="entry name" value="tRNA translation"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="52" mass="6073" checksum="42B6ED18BA590774" modified="2009-05-26" version="1">MCNAKMWRHQGSNQGPPDLQSGALPTELWHLWAFSLRYHFCTRTRRTAMAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNB9</accession>
    <name>C1MNB9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_32701</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057077.1">
        <property type="nucleotide sequence ID" value="XM_003057031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNB9"/>
    <dbReference type="STRING" id="564608.C1MNB9"/>
    <dbReference type="GeneID" id="9682992"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32701"/>
    <dbReference type="eggNOG" id="ENOG502SFBQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VMNSGHI"/>
    <dbReference type="OrthoDB" id="785538at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_bS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_bS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="Ribosomal_bS21_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="35"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="103" mass="11666" checksum="33E902D28122E94C" modified="2009-05-26" version="1">MFAFKGSYQAEVTVGENEAGESAIRRFRRAVMNSGHINETRRRRYFENPQDIKKRKQSTPRKKKGAKPRTAAQALAEKEQAAMNPRERRGGFGNANNGGEGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNE6</accession>
    <name>C1MNE6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_14737</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057091.1">
        <property type="nucleotide sequence ID" value="XM_003057045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNE6"/>
    <dbReference type="GeneID" id="9682106"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14737"/>
    <dbReference type="eggNOG" id="KOG2355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MCDYLLV"/>
    <dbReference type="OrthoDB" id="6512918at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158">
        <property type="entry name" value="SKFA PEPTIDE EXPORT ATP-BINDING PROTEIN SKFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158:SF2">
        <property type="entry name" value="SKFA PEPTIDE EXPORT ATP-BINDING PROTEIN SKFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="22"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="297" mass="32301" checksum="EF69AE07793DAACD" modified="2009-05-26" version="1">MTAVTAPAAEPPTDNATDTGSLKIRALAYAYPGGESILNDVTLDLPPGSRCLLSGANGAGKSTLLQILAGKTMVDRDAVRVIGKPPFHEIELTCSGDLGYLGSQWRRTIGSAGSVALAGDFTAGKMIFGVEDVDPERRARLVQLLDIDLDWSMMKVSDGQRRRVQICMGLLKPFKVLLCDEITVDLDILGRLDLLEFLKSECEERGATVVYATHIFDGMEPWMTHVAFVSNGALAHGGRKSDVVGLKGVKHLLGTIDAWLRVDRDERRAREAIAATAPKKTATDRFSNVSRHMGYYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNV8</accession>
    <name>C1MNV8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_32152</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056711.1">
        <property type="nucleotide sequence ID" value="XM_003056665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNV8"/>
    <dbReference type="STRING" id="564608.C1MNV8"/>
    <dbReference type="GeneID" id="9682619"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32152"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WPHPETF"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF134">
        <property type="entry name" value="CAROTENE EPSILON-MONOOXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="549" mass="60883" checksum="4F00B164FC4A69A3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNY1</accession>
    <name>C1MNY1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56073</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056723.1">
        <property type="nucleotide sequence ID" value="XM_003056677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNY1"/>
    <dbReference type="STRING" id="564608.C1MNY1"/>
    <dbReference type="GeneID" id="9682630"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56073"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="106" mass="11568" checksum="AD781D7D49603443" modified="2009-05-26" version="1">MSFRLCADTTGVRETAARPVAVETNSGRNPSPSKVAIRRGRRDREGRARRHVRARFAGGTKGFEEALEPFGLKPADPAFWTDALDAHLGSLMDEAEALAKKLAYAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP30</accession>
    <name>C1MP30_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_38652</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056748.1">
        <property type="nucleotide sequence ID" value="XM_003056702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP30"/>
    <dbReference type="STRING" id="564608.C1MP30"/>
    <dbReference type="GeneID" id="9682187"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38652"/>
    <dbReference type="eggNOG" id="KOG0045">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF423">
        <property type="entry name" value="LEUCINE-RICH REPEAT PROTEIN (LRRP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="3">
        <location>
            <begin position="60"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="active site" evidence="1 2">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" evidence="1 2">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <feature type="active site" evidence="1 2">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="420" mass="46697" checksum="1EEC1D8FE189441A" modified="2009-05-26" version="1">MLQEDWEKQRCTVFLRPSEVTATLQFDKEKDRSGAFTVLEWKCRLLSPDVEVKDDGHEKLWLQPYTHDGKTIKTRGVSPGRVKGLADVPSLCLWNTISPNDLNQRGGVCNCYMVASFAALAEWPGAIKKLFRKTKGADEMPRSNAANEYTITLYDLESAPVAREVDVVVNERLAVDVDKGKKLGLPISDCAELWPCYLEKALVVHCGGWNGIGSGGKPSHVLEILTGCPNAYDLTLKDFVCCGNSAGEKRGNSVKKRKGVGRYRKPWPSANGKPVVQPKTQDGCIDALYAYDKANYPMCCFSARDGNTAATRADGFIDIHAYTLIRVEKNVAGSGVDMLLLRNPHGTNELTRGMWVDDGPGWKKHPEIRKAIQPVFENDGAFWVEKSEFFKYVDYVTVLALDMTTFVKSSYAPPPLFEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP32</accession>
    <name>C1MP32_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Folylpolyglutamate synthase</fullName>
            <ecNumber evidence="17">6.3.2.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Folylpoly-gamma-glutamate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Tetrahydrofolylpolyglutamate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MICPUCDRAFT_25571</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + L-glutamate + ATP = (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10580"/>
            <dbReference type="Rhea" id="RHEA-COMP:14738"/>
            <dbReference type="Rhea" id="RHEA-COMP:14740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:141005"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>a monovalent cation</name>
            <dbReference type="ChEBI" id="CHEBI:60242"/>
        </cofactor>
        <text evidence="17">A monovalent cation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 17">Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.17" evidence="17"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056749.1">
        <property type="nucleotide sequence ID" value="XM_003056703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP32"/>
    <dbReference type="STRING" id="564608.C1MP32"/>
    <dbReference type="GeneID" id="9682655"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25571"/>
    <dbReference type="eggNOG" id="KOG2525">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RETEWAG"/>
    <dbReference type="OrthoDB" id="5212574at2759"/>
    <dbReference type="UniPathway" id="UPA00850"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.10:FF:000008">
        <property type="entry name" value="Folylpolyglutamate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023600">
        <property type="entry name" value="Folylpolyglutamate_synth_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF5">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038895">
        <property type="entry name" value="FPGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="13 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 17" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="20">
        <location>
            <begin position="381"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR038895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR038895-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR038895-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EEH58394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="574" mass="61910" checksum="FA2CE3B746302B46" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP41</accession>
    <name>C1MP41_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_45348</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056755.1">
        <property type="nucleotide sequence ID" value="XM_003056709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP41"/>
    <dbReference type="STRING" id="564608.C1MP41"/>
    <dbReference type="GeneID" id="9682194"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45348"/>
    <dbReference type="eggNOG" id="ENOG502QVJR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FWILRDA"/>
    <dbReference type="OrthoDB" id="3833at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009472">
        <property type="entry name" value="Tab2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046761">
        <property type="entry name" value="Tab2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046760">
        <property type="entry name" value="Tab2-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34556">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34556:SF2">
        <property type="entry name" value="PROTEIN TAB2 HOMOLOG, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20429">
        <property type="entry name" value="Tab2-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06485">
        <property type="entry name" value="Tab2-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA-binding protein Tab2-like N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding protein Tab2/Atab2 C-terminal" evidence="2">
        <location>
            <begin position="111"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="270" mass="30379" checksum="FD0CC45193C71260" modified="2009-05-26" version="1">MKDERGKKMWELLICDESRSFQHAEFFPNNRINSVELSKAIQRVLNEQGARPKRFKFFRSQMQTIITRACNDVGVPPLPSRRCQTLTRWLDQRAEEVYKKHPGYDGSSSPMMGFETSAPKPLPDALRGESWAFVALPLIGVKEEAMQVSANRVFGDLLDIDEALPDDTLVPGIAVYTRRAAALAGWTKGLELGGISVDLDMGTLILDTGVADSWQYARFRQTKELTREAKEWEDVKAAAGGLHFLAIQTDEEAESTDGFWILQDFTASQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPA5</accession>
    <name>C1MPA5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_38696</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056786.1">
        <property type="nucleotide sequence ID" value="XM_003056740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPA5"/>
    <dbReference type="GeneID" id="9682691"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38696"/>
    <dbReference type="OMA" id="GEMDERQ"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14371">
        <property type="entry name" value="CUE_CID7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041806">
        <property type="entry name" value="CID5/6/7_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="181"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="378" mass="41614" checksum="65E13DFF390FD59C" modified="2009-05-26" version="1">MRATASSFVPKKAPDPSTVAAAAAATPFYPQAQAQPVESYPETYAEQDGELPKKKSFADLGLDSLGFVSEDDGEDNGDDAPSPLTQRIRERAEQRVASESDAYAAEQARGYYEYQPNQERQYDDAGWAHHQQYVGEYHPHQQQYAPQYEYYGGHDNDAHPGVNEYGYEQAWDGHDDGGEMDERQFLSLLMESFPGYSLESLEELLAANNHDMEMTVEMLTEMDTLEEPPEPPSLDDESNFPSLGGGSGGPEAPPPPIEVFRSFTISGGRSNMRLPSPADAPRFTSADENGNFAARVRTQSAVPQAHDRGSVQVGYGTGNFRGGSSAASHQPWVETGEAVSDIKRRKRTCPGTKRSRRNSAGRVVVTPKRCEPRTTRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPJ1</accession>
    <name>C1MPJ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_46925</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057966.1">
        <property type="nucleotide sequence ID" value="XM_003057920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPJ1"/>
    <dbReference type="STRING" id="564608.C1MPJ1"/>
    <dbReference type="GeneID" id="9683066"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46925"/>
    <dbReference type="eggNOG" id="KOG4446">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="568084at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010796">
        <property type="entry name" value="C2_B9-type_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968">
        <property type="entry name" value="B9 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968:SF4">
        <property type="entry name" value="TECTONIC-LIKE COMPLEX MEMBER MKS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07162">
        <property type="entry name" value="B9-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51381">
        <property type="entry name" value="C2_B9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="693"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="765"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="854"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="56"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="697"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="786"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="822"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="893" mass="94692" checksum="A63DA97B36A965BC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPR2</accession>
    <name>C1MPR2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46948</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057627.1">
        <property type="nucleotide sequence ID" value="XM_003057581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPR2"/>
    <dbReference type="STRING" id="564608.C1MPR2"/>
    <dbReference type="GeneID" id="9683435"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46948"/>
    <dbReference type="eggNOG" id="KOG3624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="1">
        <location>
            <begin position="14"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="195" mass="20564" checksum="B7D630FF85AAB429" modified="2009-05-26" version="1">MGKGTEGGAPARAQDDLYAHVNREWLDANPVPAAYGRWGTFEMLNDAALENTKICLEEAGDGDKGGAFLASGMRAAEQDSRAALAPTLKLAREFAAAAAAKDANALAVAIAEMHVFGVSSLFGVGDTPDKKNSEWSIVGVAQGGVALPDRDYYLSADPDRVALRAKYVAHVAKMLTLVGGEYEDAAVAEVRSIHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPT2</accession>
    <name>C1MPT2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_46957</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057638.1">
        <property type="nucleotide sequence ID" value="XM_003057592.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MPT2"/>
    <dbReference type="GeneID" id="9683444"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46957"/>
    <dbReference type="eggNOG" id="KOG2051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DFQHHQI"/>
    <dbReference type="OrthoDB" id="27832at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039762">
        <property type="entry name" value="Nmd2/UPF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007193">
        <property type="entry name" value="Upf2/Nmd2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839:SF7">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04050">
        <property type="entry name" value="Upf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G" evidence="4">
        <location>
            <begin position="559"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G" evidence="4">
        <location>
            <begin position="764"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="320"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="895"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1015"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1185"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1275"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="895"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1018"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1040"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1092"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1284"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1305"/>
            <end position="1316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1323" mass="140441" checksum="30391998E7D49A15" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ58</accession>
    <name>C1MQ58_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57169</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058069.1">
        <property type="nucleotide sequence ID" value="XM_003058023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ58"/>
    <dbReference type="GeneID" id="9683012"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57169"/>
    <dbReference type="OMA" id="MLIVEHQ"/>
    <dbReference type="OrthoDB" id="10250504at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="57"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="271" mass="29997" checksum="2769669900DD93EA" modified="2009-05-26" version="1">MAASGGDPGTSASGRKRQRNENASEEEDKEDEPTATEEPPPDEERSTEEEDDDAPIEIDEDDDPVELLVAQGVSEEVARRALENADGDVDEAVMEVIRLRELEEEERDMAKGMEESLREAEEEATKREAELAEKKRTAPAEYFAGSSFLSHLGVDASERLLREESSSRDDVMQLLDFERQCKKWYRGNGKEVDSKFAAIAAEIVANLPDVDAAKEESGETDMLHSLIVAHLMTLREAVLAHVPEKSGSVPEIFSPTKTADEIEEVDLCDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQS2</accession>
    <name>C1MQS2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">H+-or Na+-translocating f-type, v-type and A-type ATPase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_57391</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase e1/e2 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058177.1">
        <property type="nucleotide sequence ID" value="XM_003058131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQS2"/>
    <dbReference type="STRING" id="564608.C1MQS2"/>
    <dbReference type="GeneID" id="9683245"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57391"/>
    <dbReference type="eggNOG" id="ENOG502SB4J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TSVFCCW"/>
    <dbReference type="OrthoDB" id="1508846at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008389">
        <property type="entry name" value="ATPase_V0-cplx_e1/e2_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05493">
        <property type="entry name" value="ATP_synt_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912034" evidence="10">
        <location>
            <begin position="19"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH58128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="68" mass="7644" checksum="3FCBB8047EE636B8" modified="2009-05-26" version="1">MGLALGTVLFLALEAAFALFVNARWRAHDRGLKHVLFAASVFCCWLMWAIVYASQMHPLIRPVISREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQT3</accession>
    <name>C1MQT3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57403</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058183.1">
        <property type="nucleotide sequence ID" value="XM_003058137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQT3"/>
    <dbReference type="GeneID" id="9683621"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57403"/>
    <dbReference type="OMA" id="TTGPERI"/>
    <dbReference type="OrthoDB" id="3335358at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.20">
        <property type="entry name" value="Protein of unknown function DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009297">
        <property type="entry name" value="DUF952"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129">
        <property type="entry name" value="BLR1139 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129:SF1">
        <property type="entry name" value="DUF952 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06108">
        <property type="entry name" value="DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="186" mass="19893" checksum="83C006C7D2AF7CF0" modified="2009-05-26" version="1">MAHLKDKYEYWDVDATPPGLEVLWKIVSPADLAKWQEAGGISGSELDRKDGFIHTSNGRMVREVAARFFKGVGDAVLLKMLPEEWPLAVIWSPDEPVGVLKRPVTGSVSVHWLPDGCAHVYHSDPLPLECVAETHPMPLGADGVHVFPEGMEDKPVDVTPGPEVHPAHGGPGPGGAGPGDGDAMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR52</accession>
    <name>C1MR52_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57528</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058243.1">
        <property type="nucleotide sequence ID" value="XM_003058197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR52"/>
    <dbReference type="GeneID" id="9683309"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57528"/>
    <dbReference type="eggNOG" id="ENOG502QVT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HARPSHE"/>
    <dbReference type="OrthoDB" id="498301at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016422">
        <property type="term" value="F:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099122">
        <property type="term" value="F:RNA polymerase II C-terminal domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039881">
        <property type="entry name" value="PCIF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022035">
        <property type="entry name" value="PCIF1_WW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21727:SF0">
        <property type="entry name" value="MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21727">
        <property type="entry name" value="PHOSPHORYLATED CTD INTERACTING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12237">
        <property type="entry name" value="PCIF1_WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCIF1 WW" evidence="2">
        <location>
            <begin position="245"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="547" mass="58570" checksum="2B4A999AF5CB6727" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRY3</accession>
    <name>C1MRY3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nicastrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_58275</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nicastrin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058588.1">
        <property type="nucleotide sequence ID" value="XM_003058542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRY3"/>
    <dbReference type="STRING" id="564608.C1MRY3"/>
    <dbReference type="GeneID" id="9684027"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58275"/>
    <dbReference type="eggNOG" id="KOG2657">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GEGNACY"/>
    <dbReference type="OrthoDB" id="10265862at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041084">
        <property type="entry name" value="Ncstrn_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008710">
        <property type="entry name" value="Nicastrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21092">
        <property type="entry name" value="NICASTRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21092:SF0">
        <property type="entry name" value="NICASTRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18266">
        <property type="entry name" value="Ncstrn_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05450">
        <property type="entry name" value="Nicastrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0914">Notch signaling pathway</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912098" description="Nicastrin" evidence="10">
        <location>
            <begin position="24"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Nicastrin small lobe" evidence="11">
        <location>
            <begin position="53"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="796" mass="80714" checksum="AD052383DE793AF8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS00</accession>
    <name>C1MS00_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Caltractin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Centrin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_27001</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This calcium-binding protein is found in the basal body complexes (the functional homolog of the centrosome in animal cell). In mitotic cells it is specifically associated with the poles of the mitotic spindles at the sites of the duplicated basal body complexes.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058965.1">
        <property type="nucleotide sequence ID" value="XM_003058919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS00"/>
    <dbReference type="STRING" id="564608.C1MS00"/>
    <dbReference type="GeneID" id="9684034"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27001"/>
    <dbReference type="eggNOG" id="KOG0028">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EFREIMM"/>
    <dbReference type="OrthoDB" id="343296at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15898">
        <property type="entry name" value="EFh_PI-PLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF59">
        <property type="entry name" value="EF-HAND SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="29"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="65"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="102"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="138"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH57420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="19514" checksum="D9EA158844256FB0" modified="2009-05-26" version="1">MLKKQQQAVGGFVHAAPKKKKVLKELTPEEDAELREAFNLFDADGSGTIDMRELKVAMRALGFAVSSEDVKAIMTEYDADGSGEIEYPEFRNVMRDKMASRNPEDELAKAFKVFDDDSSGKITLKNLRRIAKELGEDVDDDELRAMIDEFDARGAGYIDERTFLDIMHKGADAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS25</accession>
    <name>C1MS25_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58319</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058612.1">
        <property type="nucleotide sequence ID" value="XM_003058566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS25"/>
    <dbReference type="GeneID" id="9684412"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58319"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="236" mass="26318" checksum="2FFAE7C176A7F108" modified="2009-05-26" version="1">MGDWKRDVEKWGDEKGRSPIVTNKTPKQKKAFDPESPSTAKIGQSPGSSDPSSPLTTTAEYRSSRMARARSLSDQRSRPYGRDQAAPDSPDNDPRLLDEEWASQRSPLVCESGYHPIDRGLSRSPQVIADKFKGRHDVDDALRHREHRGSPGSPKSPDVDVDPRHRDGWIGNVNASPSGHGKNTDAKMGRNKLEKGEMDRAYNIIHARPPQSNDQPEVRSIHWSSYDPVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSB7</accession>
    <name>C1MSB7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58424</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059024.1">
        <property type="nucleotide sequence ID" value="XM_003058978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSB7"/>
    <dbReference type="GeneID" id="9684092"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58424"/>
    <dbReference type="eggNOG" id="ENOG502T1VG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ADKCTRC"/>
    <dbReference type="OrthoDB" id="498789at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="334" mass="35718" checksum="8B4D5A7D32609003" modified="2009-05-26" version="1">MRSRSVSGVSVSDSDSESGSGRSGSGSSRDRGRARRRHDSSSEDESDSDAGGGARRGGNERDEDKERRKREKKEKKKLKKAEKKARKKAKKAAKRDAKDAKRRAKKRSRRDDDGDDGGDGDGDGDGGGGGGGEVRRHDDAHARVRDVPPPPRFPDAPEPTTKKPKGGLETRSREMVESEKADAAALAAADAAARRKAEEDAAAAKAASDAAEEEARAKLAESVDATPPVPGFGAAMTLEQYRAMAAQKTYLRGTIHATPQEDKDEEMDKAKKGWWACQSYKCTKGGGANHMNPKYADKCTRCNAMKPLGAGAGTFSHGMSEKAYLANSSKRLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSD6</accession>
    <name>C1MSD6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58446</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059034.1">
        <property type="nucleotide sequence ID" value="XM_003058988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSD6"/>
    <dbReference type="STRING" id="564608.C1MSD6"/>
    <dbReference type="GeneID" id="9684101"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58446"/>
    <dbReference type="eggNOG" id="KOG0887">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YRTNKHH"/>
    <dbReference type="OrthoDB" id="504467at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.190:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.190">
        <property type="entry name" value="translation elongation factor selb, chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00573">
        <property type="entry name" value="Ribosomal_eL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001780">
        <property type="entry name" value="Ribosomal_eL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018266">
        <property type="entry name" value="Ribosomal_eL33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038661">
        <property type="entry name" value="Ribosomal_eL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10902">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01247">
        <property type="entry name" value="Ribosomal_L35Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01105">
        <property type="entry name" value="RIBOSOMAL_L35AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="109" mass="12221" checksum="CF5E49DC45EFF0E0" modified="2009-05-26" version="1">MPKGESCRLYVRGIILGYKRARTNQTNHTSLIKLENVNTSPDASFYLGKKLCYVYKAKTKKKGTTYRTSWGKVTRAHGTSGVVRAKFKKNLPPSSMGGKIRCMLYPSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSH3</accession>
    <name>C1MSH3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_16926</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058680.1">
        <property type="nucleotide sequence ID" value="XM_003058634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSH3"/>
    <dbReference type="STRING" id="564608.C1MSH3"/>
    <dbReference type="GeneID" id="9684119"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16926"/>
    <dbReference type="eggNOG" id="ENOG502QT36">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IRWQRIP"/>
    <dbReference type="OrthoDB" id="513341at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF52">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="86" mass="9801" checksum="E8217B9A25BE6E2C" modified="2009-05-26" version="1" fragment="single">MKAGKDSGCYGRLSYDEPHPTVHSYHKPHWHPSLVPYAPRVMSVREKARIQGFPDRFVFKGTVHQQYKQIANAVSPQLTKALARSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSH7</accession>
    <name>C1MSH7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58490</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059055.1">
        <property type="nucleotide sequence ID" value="XM_003059009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSH7"/>
    <dbReference type="STRING" id="564608.C1MSH7"/>
    <dbReference type="GeneID" id="9684121"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58490"/>
    <dbReference type="eggNOG" id="KOG1672">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RIDEVCD"/>
    <dbReference type="OrthoDB" id="10257948at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21148">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="365" mass="39127" checksum="0FB5FE7EC4C7C227" modified="2009-05-26" version="1">MGQPPPPACADDACDTGKCTSWVDEALDAAGEEYADAPRPGSCCEKDAKAQKEAARIKRILRAHDPVARLEAVRAAGGVMERANLDEDEEDEDEEDEDSDDLLTDDDDDDDDLRMASTMDPVLREIHERRLAEMKAAAAKNAATRQREGASSYNAAKEADIPTIVKSGPSRVVFHFVLEGMDECARIDEVLDALAPAHPKTRFVRVDALCPSPMLRTIGAPTLPAVITFRRKKLGAWTCGLNDFGGVEGFDEEKVIRWLARVAGALPGHPLAPPPPSKGGVAGGANGDSSDEGEKPSKGRGADGDGSDDDDEVVPCEAGEGAWSGVGGTPCETCGRRYPHQHFRALRHGGERERRGSDDEEEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSN8</accession>
    <name>C1MSN8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Meiosis-specific nuclear structural protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_57758</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis. Required for sperm flagella assembly. May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC). ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Flagellum axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MNS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058708.1">
        <property type="nucleotide sequence ID" value="XM_003058662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSN8"/>
    <dbReference type="STRING" id="564608.C1MSN8"/>
    <dbReference type="GeneID" id="9683791"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57758"/>
    <dbReference type="eggNOG" id="ENOG502QS9D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QIRNQMV"/>
    <dbReference type="OrthoDB" id="197839at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026504">
        <property type="entry name" value="MNS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043597">
        <property type="entry name" value="TPH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19265">
        <property type="entry name" value="MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19265:SF0">
        <property type="entry name" value="MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13868">
        <property type="entry name" value="TPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="7 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-0469">Meiosis</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trichohyalin-plectin-homology" evidence="16">
        <location>
            <begin position="132"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="72"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="264"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF13868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH57163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="522" mass="60424" checksum="8EA9061E415E6A56" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSR7</accession>
    <name>C1MSR7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoporin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57796</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058724.1">
        <property type="nucleotide sequence ID" value="XM_003058678.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MSR7"/>
    <dbReference type="GeneID" id="9683807"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57796"/>
    <dbReference type="eggNOG" id="KOG4521">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DWLESFA"/>
    <dbReference type="OrthoDB" id="514940at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056548">
        <property type="entry name" value="HEAT_Nup120"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021717">
        <property type="entry name" value="Nucleoporin_Nup160"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23300">
        <property type="entry name" value="HEAT_Nup120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoporin nup120-like HEAT repeat" evidence="2">
        <location>
            <begin position="982"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1298"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1299"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1317"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1345"/>
            <end position="1359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1668" mass="169755" checksum="B34C1B73D24A483B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTA5</accession>
    <name>C1MTA5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57996</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058831.1">
        <property type="nucleotide sequence ID" value="XM_003058785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTA5"/>
    <dbReference type="STRING" id="564608.C1MTA5"/>
    <dbReference type="GeneID" id="9684270"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57996"/>
    <dbReference type="eggNOG" id="KOG0440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FRVYSHM"/>
    <dbReference type="OrthoDB" id="8170117at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.30:FF:000001">
        <property type="entry name" value="MOB kinase activator 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="260" mass="28197" checksum="0C28D28716EE2CFC" modified="2009-05-26" version="1">MFWPSSSTQRTFRCAPAAGASLAPSRFRALGDPTPPSARRPKKNAPVGSKGAALKQHIDATLGSGNLREAVLLPPGEDLNEWLAVNTVDFYNAISMLYATLGEYCTDKNCPTMCAGPKYEYRWADGVKVKKPIECSAPRYVDYLLEWVESQVDDEATFPQASGAAFPKNFQSITSKIFSRLFRVYAHIYHSHFNQIVSLGAEAHLNTCFKHFIYFTGAFSLVKREELAPLGELVDGILGGVQIPGGSRGSGSGAGVPNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTI2</accession>
    <name>C1MTI2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_33531</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 14-3-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058494.1">
        <property type="nucleotide sequence ID" value="XM_003058448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTI2"/>
    <dbReference type="STRING" id="564608.C1MTI2"/>
    <dbReference type="GeneID" id="9684307"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33531"/>
    <dbReference type="eggNOG" id="KOG0841">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MIKNYRQ"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000001">
        <property type="entry name" value="14-3-3 gamma 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="9"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="256" mass="28822" checksum="F97E3170308DE695" modified="2009-05-26" version="1">MSDGTLTERERLVYSAKLAEQAERYDEMVESMKALCKLDAVELSIEERNLLSVGYKNVIGARRASWRILSSNEDKERVKNHEANSAQIKSYRGRVEKELNDICGEILSILDNNLITPAASDESKVFYHKMKGDYYRYLAEFLASDERARVAGLAAEAYEQASEIARDDAPDKGLPPTHPIRLGLALNYSVFHFEIQNKPQQACALAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDITDGDEGDGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTX0</accession>
    <name>C1MTX0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_69390</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059394.1">
        <property type="nucleotide sequence ID" value="XM_003059348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTX0"/>
    <dbReference type="GeneID" id="9684834"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69390"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="593" mass="66826" checksum="99FD85C4764A111E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUB7</accession>
    <name>C1MUB7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome oxidase biogenesis family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_3586</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXA1/ALB3/YidC (TC 2.A.9.2) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059469.1">
        <property type="nucleotide sequence ID" value="XM_003059423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUB7"/>
    <dbReference type="STRING" id="564608.C1MUB7"/>
    <dbReference type="GeneID" id="9684607"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3586"/>
    <dbReference type="eggNOG" id="KOG1239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IMTDIAD"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF65">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="8">
        <location>
            <begin position="31"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="240" mass="26468" checksum="24F1A2B2E6D40FBD" modified="2009-05-26" version="1" fragment="single">EVIAIAADSWITTAGLMYVIEYFHLAHGMEWYAAIAAATCVMRVCAFPLTIMQQKSAGKMHLAKPEMTALQESINEARRAGEHERAARLGRVFAIWSKHDVHPAKMLAPLLFQAPVFISFYFAISRMAEGLPSMRDGGFAWFQDLSIADPTFALPIISSLTFLAAVEFAPQNPAVKSSQREMTKWGLRALGVAMVPLTASFPSGVFVYWITSNVFSFAQTVLLRVPFAKRAMGIPEDPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUF8</accession>
    <name>C1MUF8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_69556</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059189.1">
        <property type="nucleotide sequence ID" value="XM_003059143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUF8"/>
    <dbReference type="STRING" id="564608.C1MUF8"/>
    <dbReference type="GeneID" id="9684629"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69556"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="208" mass="22799" checksum="953769BB22F91607" modified="2009-05-26" version="1">MAESEGGRRPRRAAAKAALLANQHQSAPSAMHYVGYVEEEETPEMIMQKFAQLEKIQEEAAAAKEAAATAKAAAAAEAGDDAPIDDDATNDSNAKNDDDGFDEEMLLKVFKQTSQFSMKKALAEELFFDGDAMDHEDDLWDDEAGGWDLNDIFGKAKRKASRIARGPREPRAPKAQKSHMITAYNSDNQARSVHWSPYDRVGVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUH6</accession>
    <name>C1MUH6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_40208</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059495.1">
        <property type="nucleotide sequence ID" value="XM_003059449.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MUH6"/>
    <dbReference type="GeneID" id="9684640"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40208"/>
    <dbReference type="eggNOG" id="KOG1888">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FDWHANC"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46817">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHATASE SAC9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46817:SF1">
        <property type="entry name" value="SAC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="3">
        <location>
            <begin position="110"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="524"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1127"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1186"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="577"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1137"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1186"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1203"/>
            <end position="1224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1369" mass="140633" checksum="F51D11B5032E1C9B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUK3</accession>
    <name>C1MUK3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mg-protoporphyrin IX chelatase</fullName>
            <ecNumber evidence="9">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CHLD1</name>
        <name evidence="12" type="ORF">MICPUCDRAFT_18092</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>protoporphyrin IX + Mg(2+) + ATP + H2O = Mg-protoporphyrin IX + ADP + phosphate + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60492"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.6.1.1"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Redox regulation; active in reducing conditions, inactive in oxidizing conditions.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The magnesium chelatase complex is a heterotrimer consisting of subunits CHLI, CHLD, AND CHLH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Plastid</location>
            <location evidence="9">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mg-chelatase subunits D/I family.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="9"/>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059510.1">
        <property type="nucleotide sequence ID" value="XM_003059464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUK3"/>
    <dbReference type="STRING" id="564608.C1MUK3"/>
    <dbReference type="GeneID" id="9684950"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18092"/>
    <dbReference type="eggNOG" id="ENOG502QU3C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YYHLPKA"/>
    <dbReference type="OrthoDB" id="299997at2759"/>
    <dbReference type="UniPathway" id="UPA00668"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01451">
        <property type="entry name" value="vWA_Magnesium_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.80">
        <property type="entry name" value="Magnesium chelatase subunit I, C-Terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041702">
        <property type="entry name" value="BchD/ChlD_VWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011776">
        <property type="entry name" value="Mg_chelatase_ATPase-dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02031">
        <property type="entry name" value="BchD-ChlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43473">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43473:SF2">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 9" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="11">
        <location>
            <begin position="491"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="329"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="354"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH56642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="694" mass="75457" checksum="E9EE75BDE4BC70A9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUM9</accession>
    <name>C1MUM9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_27297</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059224.1">
        <property type="nucleotide sequence ID" value="XM_003059178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUM9"/>
    <dbReference type="STRING" id="564608.C1MUM9"/>
    <dbReference type="GeneID" id="9684964"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27297"/>
    <dbReference type="eggNOG" id="ENOG502SE4B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GWNREKK"/>
    <dbReference type="OrthoDB" id="431691at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_bL34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_bL34"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="127" mass="13382" checksum="2D3A721ED5ED00E3" modified="2009-05-26" version="1">MATLSLCASMSSLAVSRPKATLSCKSPAKGMTMKAALAAPTPFRAVALRTPTTHGRGALVVVAGGNSIGNTLHGTRRARARTSGFRARLQSPTGRRVLKARRAKGRKYLAPAGAVNGWNREKKKSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUN4</accession>
    <name>C1MUN4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_33947</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059526.1">
        <property type="nucleotide sequence ID" value="XM_003059480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUN4"/>
    <dbReference type="STRING" id="564608.C1MUN4"/>
    <dbReference type="GeneID" id="9684667"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33947"/>
    <dbReference type="eggNOG" id="KOG0283">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="408728at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040324">
        <property type="entry name" value="WDR44/Dgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221">
        <property type="entry name" value="WD REPEAT DOMAIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="363"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="441"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="481"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="63"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="224"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="746"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="753"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="772"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="825" mass="86540" checksum="C842E8ED9398ED53" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV62</accession>
    <name>C1MV62_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_59066</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059320.1">
        <property type="nucleotide sequence ID" value="XM_003059274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV62"/>
    <dbReference type="GeneID" id="9685051"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59066"/>
    <dbReference type="eggNOG" id="KOG1443">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EDEMAWQ"/>
    <dbReference type="OrthoDB" id="18894at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="83"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="29"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="479"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="503" mass="53006" checksum="5757EABEE2C07B24" modified="2009-05-26" version="1">MSVAAAAAAKIQRRYREWRTRRLMKRHRRRLVAGSDDDDDDDSSSEDDDDAVDDERRRLHRASSSSAAAAPPSEARRRAKLVKCALLAIAWFTLSTGLAVFNKALFGQRKGGFPAPLLLTACQFAMQYALASAIVHRAFGGALRPKREVPAEVYWRRVAPVGAAMGMDIALSNLSLVFVTVSFYTLVKTSSIIFLLLFAFALKLEPVSFRLMGVAALLTGGQALTVDGETRFDARGCALVVAAAACSGLRWTLSQIVLQGKEPGGGGGGAGDNKNTNGRDGSRRDPRRLRKSYGLSHPVVMLKTMTPLMCGVVLAFRRVLYTGSHTTPLACLLTERPWDALPGSAWLSGPGDFVVDLMIVTCGACAALAMTVAEFEARPLLKETSAVTVMVIGVAKDVVQVLTAIAVYGDAFGVENGMGMALVLGGIVAYNRHKALAAEERAAALGTMAGAGAGAGAGEGVARGPGLGLGGSAEREIGLPRVVPRRSGGLSAVPNLPRRDAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVL5</accession>
    <name>C1MVL5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_40554</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060058.1">
        <property type="nucleotide sequence ID" value="XM_003060012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVL5"/>
    <dbReference type="STRING" id="564608.C1MVL5"/>
    <dbReference type="GeneID" id="9685213"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40554"/>
    <dbReference type="OrthoDB" id="1932312at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="200"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="54"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="34381" checksum="6BAD8E103E7E8424" modified="2009-05-26" version="1">MEFVDEGIHRNNPDALRAAALIANGLGARARWVSHQGVDYGTFRRAILLRAKEKGATTTDAAATSGEAASGRAVPGSPSLPTSSRASSVDGDWNDDGGGGGGDEETRDRKRAGARRTTTTTSTRRASALRSAGPVRHTHASGVSRVRWSKMGPRVLAVGRECGVVELVAFERGRANASAPSSSSSSSSSSSASFERVASLDGHTAAVTDIDWTLDGGALATSSLDGAVRLWSRPRPGAAVAADAAAADDDDASGGWRCARAIPCGAAVHAVRFHPINANLLVVGLETAAVWLLNASTGHRAACATSRSYMRSPVGCLAWCVPYTGPHTPALAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVY2</accession>
    <name>C1MVY2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flagellar inner dynein arm light chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">IDA4</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_59554</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the inner dynein arm light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060118.1">
        <property type="nucleotide sequence ID" value="XM_003060072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVY2"/>
    <dbReference type="STRING" id="564608.C1MVY2"/>
    <dbReference type="GeneID" id="9685270"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59554"/>
    <dbReference type="eggNOG" id="KOG4001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QVTIICA"/>
    <dbReference type="OrthoDB" id="273640at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019347">
        <property type="entry name" value="Axonemal_dynein_light_chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13183:SF0">
        <property type="entry name" value="AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13183">
        <property type="entry name" value="AXONEMAL INNER ARM DYNEIN LIGHT CHAIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10211">
        <property type="entry name" value="Ax_dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="2 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0243">Dynein</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-0505">Motor protein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="186"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="262" mass="29932" checksum="CC2738038C4D2B8E" modified="2009-05-26" version="1">MLPPLHTLVLYDQPQTVRRPRASLHRAENEHSFRSLRFASPRARKGDGGAAKTQTEDILNSILPPREHVEDGTLWVQYVAPTPATRLDVINLQEKLDARLQARPTRQARETGLCPVREELYAQCLDEMIRQVTINCAERGLLLLRIRDEMRMTIQAYQTLYESSVAFGVRKALQTEQGKSDMEARILQARSSIALLETDKADLERQCAEWKAKCEAIEKRESERRADEEAKHGDEIAYLNRSNKQLKAQLDKFLSPEAAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW07</accession>
    <name>C1MW07_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47739</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060130.1">
        <property type="nucleotide sequence ID" value="XM_003060084.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MW07"/>
    <dbReference type="GeneID" id="9685283"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47739"/>
    <dbReference type="eggNOG" id="ENOG502SAUE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3789175at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="2">
        <location>
            <begin position="589"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="903"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="910"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1344" mass="143217" checksum="6BCD598D15B2293A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW87</accession>
    <name>C1MW87_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59667</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060172.1">
        <property type="nucleotide sequence ID" value="XM_003060126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW87"/>
    <dbReference type="GeneID" id="9685321"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59667"/>
    <dbReference type="eggNOG" id="ENOG502QSDG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="508889at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="118" mass="12866" checksum="71E33262D2754932" modified="2009-05-26" version="1">MGYIMHAGQAQEPVPIRRGALNLYGQKGWYDFFATRASLTNDGFLDDSTVGMKHVAVRDSDRESSFKPASGNVCPRPKGWKPIQSNTLKPPVVARAPVVVEPEVATASFQKDSEGSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX35</accession>
    <name>C1MX35_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_60015</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060329.1">
        <property type="nucleotide sequence ID" value="XM_003060283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX35"/>
    <dbReference type="STRING" id="564608.C1MX35"/>
    <dbReference type="GeneID" id="9686059"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60015"/>
    <dbReference type="eggNOG" id="KOG3424">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IRVKKYM"/>
    <dbReference type="OrthoDB" id="10251131at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3370:FF:000001">
        <property type="entry name" value="40S ribosomal protein S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018098">
        <property type="entry name" value="Ribosomal_eS24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00529">
        <property type="entry name" value="RIBOSOMAL_S24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="128" mass="14709" checksum="8B1255ED6555FF01" modified="2009-05-26" version="1">MSSTSCTLRTRKFMTNRLLARRQFILDVLHPGRANVPKAELREKLAKMYDVNDDKCVSLFGFRTQFGGGKSTGFGLIYDTIDAMKKFEPKHRVIRAGLKEAVTKSRKQIKEKKNRVKKMRGGEKNKVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXE4</accession>
    <name>C1MXE4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60127</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060380.1">
        <property type="nucleotide sequence ID" value="XM_003060334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXE4"/>
    <dbReference type="GeneID" id="9686117"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60127"/>
    <dbReference type="OrthoDB" id="10560703at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="349" mass="37882" checksum="4F6430425560CB24" modified="2009-05-26" version="1">MAARKKGAKASASKKVACVAKITTAKVTKAKKKSLKAADKRRNINARSKKILRFCDLGHMRGKWMELSYRNRIGESLASVYGATFKEGSWWYENPDEDKFFAALFQRASGGKPLSQVDVARVFLKGDKRQINIHEPALRKVGLSKDALRDLFCVTKAAGGEGVVEIPQPEGDSVAFGEVPAVEEDDDDDATVDDDATVGAAGAMEEDQDLSNFGSCESGGMDDTVFHGPGGDAIWGEGKLGFGNDVVSLSQPLEDFTIGKFDDIFPQNCCVDDVDAKDPNAQLYPLQTWLQQAEMLTDGISGQLRGSPMEKSLIPHVEKINEHFSAMSAKVTQQIDANNALASFLKIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY58</accession>
    <name>C1MY58_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_60410</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060813.1">
        <property type="nucleotide sequence ID" value="XM_003060767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY58"/>
    <dbReference type="STRING" id="564608.C1MY58"/>
    <dbReference type="GeneID" id="9686250"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60410"/>
    <dbReference type="OMA" id="AFQDFGF"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF46">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="254"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="366"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="372"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH55582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="602" mass="63378" checksum="D191D26174D54BF7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYN2</accession>
    <name>C1MYN2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaphase-promoting complex subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_59963</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the APC13 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060304.1">
        <property type="nucleotide sequence ID" value="XM_003060258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYN2"/>
    <dbReference type="GeneID" id="9686035"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59963"/>
    <dbReference type="OrthoDB" id="25675at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008401">
        <property type="entry name" value="Apc13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28672">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28672:SF1">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05839">
        <property type="entry name" value="Apc13p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH55073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="63" mass="6931" checksum="0A0AE667F7E8C3F7" modified="2009-05-26" version="1">MAYRTGALLDIVDDEWRADVLPFDEIEIPPGISVPGDDGDDAATQAENDGPEKWNELALQFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ13</accession>
    <name>C1MZ13_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60563</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061135.1">
        <property type="nucleotide sequence ID" value="XM_003061089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ13"/>
    <dbReference type="GeneID" id="9686574"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60563"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="179" mass="17913" checksum="4C414E1C1D043DCA" modified="2009-05-26" version="1">MTTASSATSARVLPPRARSLARRGARTAANATRGNRAAMITTVRDDDALQAAGYFFEESDDGESGARARVGGDRWAEEDASAGSVARAAFATFVTLAAATMLVESADASKTGGGAGADATIAGGVGDSRRVLATIQGFRGGGTPSRAGAEGTMARGGNAPGPRVSDAWMQYVDATAAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ91</accession>
    <name>C1MZ91_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b6-f complex subunit PetN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cytochrome b6-f complex subunit VIII</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PetN</name>
        <name evidence="13" type="ORF">MICPUCDRAFT_63318</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PetN family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061173.1">
        <property type="nucleotide sequence ID" value="XM_003061127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ91"/>
    <dbReference type="STRING" id="564608.C1MZ91"/>
    <dbReference type="GeneID" id="9686357"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63318"/>
    <dbReference type="eggNOG" id="ENOG502T0P7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IGWAATC"/>
    <dbReference type="OrthoDB" id="567503at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009512">
        <property type="term" value="C:cytochrome b6f complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00395">
        <property type="entry name" value="Cytb6_f_PetN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036143">
        <property type="entry name" value="Cytochr_b6-f_cplx_su8_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005497">
        <property type="entry name" value="Cytochrome_b6-f_cplx_su8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03742">
        <property type="entry name" value="PetN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103451">
        <property type="entry name" value="PetN subunit of the cytochrome b6f complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH54823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="107" mass="11092" checksum="F542F5B3C71CDC96" modified="2009-05-26" version="1">MAALTQTCKIALPARSAARTTRASRRCAIVAKAAAPVDVVRVQQKAVASALTVGAVYEAMATPAAQAAMELTQVAEGEPFIVNLAWAAIMATFSFSLSLVVWGRSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N004</accession>
    <name>C1N004_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_41426</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061311.1">
        <property type="nucleotide sequence ID" value="XM_003061265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N004"/>
    <dbReference type="GeneID" id="9686482"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41426"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="188"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="305"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="324"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="451" mass="46764" checksum="30F6FED2F9CC8E7F" modified="2009-05-26" version="1">MSGPAAGVAREKSGGARRAKALSSVDASAKKRPRKGVVEKSKSGAARRGATRGIAASRDGDGDDDVRSSQSRRRDGPRAGGGDASSSDASSAPESDASPVGPLSHAGASGTSSDDDALRGGDRGGDRGDRARARPAVISRTHSSPYSIAETFDPSAHDPAVLVAACGRPLRPEDERPVPLPSRGGTSSAGATLREWRCVECARVNDASRRDCARCGGLGEKRSGDEKNPPRKIKRAADPFPPLGAAAAVGSDADDEPALLRVLLPNLTGADVGADVGAERRGGDRDRDDASWASRVAAEYETDEFPPPPPPPPPPWADAFAAEFPPPPPPPGPPPPSQPRRVVDENDYKIVTDTSPPSRRRPDASSPPNRADALEALTAALAAAANADPISDGHVSIKSHVDDAAATALRLAREAASDAFEEHLALTREDLEDVVEAVDGAMDAMERKLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0E2</accession>
    <name>C1N0E2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_62802</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061620.1">
        <property type="nucleotide sequence ID" value="XM_003061574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0E2"/>
    <dbReference type="GeneID" id="9687059"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62802"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="524" mass="57645" checksum="B00FFB39C825B3FD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N123</accession>
    <name>C1N123_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51232</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061733.1">
        <property type="nucleotide sequence ID" value="XM_003061687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N123"/>
    <dbReference type="GeneID" id="9686937"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51232"/>
    <dbReference type="eggNOG" id="KOG2088">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GARNDKQ"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023:SF6">
        <property type="entry name" value="LIPASE CLASS 3 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023">
        <property type="entry name" value="LIPASE CLASS 3 PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="144"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="621" mass="66043" checksum="D97665B9655972AB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N271</accession>
    <name>C1N271_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_29042</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062040.1">
        <property type="nucleotide sequence ID" value="XM_003061994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N271"/>
    <dbReference type="STRING" id="564608.C1N271"/>
    <dbReference type="GeneID" id="9687679"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29042"/>
    <dbReference type="eggNOG" id="KOG0326">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MNANPPF"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17940">
        <property type="entry name" value="DEADc_DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000114">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="19"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="199"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH53752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="362" mass="41075" checksum="6F34D469668B859D" modified="2009-05-26" version="1">MGIFEKGFERPSPIQEESIPIALTGRDILARAKNGTGKTAAFTIPVLEKVDVSKKIIQAILLVPTRELALQTSQVAKELGKHLDVQVMVTTGGTSLKDDIMRLHQPVHIVVATPGRLVDLASKNVAKLNNATMLVMDEADKLLSPEFQPVIAQLIDFLPRNRQILLYSATFPVTVKEFKDRYLRKPYVINLMEELTLKGITQYYAFVEEKQKVHCLNTLFSKLQINQSIIFCNSVNRVELLAKKITELGYSCFYIHAKMLQSHRNRVFHDFRNGACRNLVSSDLFTRGIDIQSVNVVINFDFPKNSETYLHRVGRSGRFGHLGISVNLITYDDRFNLFRIEQELGTEIQQIPPVIDPSVYCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2B0</accession>
    <name>C1N2B0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_51915</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062261.1">
        <property type="nucleotide sequence ID" value="XM_003062215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2B0"/>
    <dbReference type="GeneID" id="9687498"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51915"/>
    <dbReference type="OrthoDB" id="274752at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="61"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="154" mass="17100" checksum="1D6B31000C398E63" modified="2009-05-26" version="1">MNQCREGDIVKLTHSRPLSKMKKWVVAEILKPERDYAHDNTGKTRRMIIDRDEARRLRAGVEGSALAREHARMQALEEEKKREEEEATGFDVDAAARARWERLNREGGAGEGEDDDDDDDDGPGLGDGPQVIGVPSRPSYAAFRGFAAGAAGWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2L5</accession>
    <name>C1N2L5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48369</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061896.1">
        <property type="nucleotide sequence ID" value="XM_003061850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2L5"/>
    <dbReference type="GeneID" id="9687336"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48369"/>
    <dbReference type="OMA" id="MEAMDYE"/>
    <dbReference type="OrthoDB" id="513821at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="299" mass="32366" checksum="F6CCA033B7E4E442" modified="2009-05-26" version="1">MSAFTTTLLRAPLAPAVRVRVRATRRASRVARGRAATIAPRAGPDGIDRDDELNTGVLYERMKKLMETEKEETDAAVDAAIERQQAIEAGIRGDAAEREIKPGDHDQLIEHLLSTPMEAMDYETVRCGPLMTPEFRAHLTERIREAAARGPLGDDVLCELQALEKWTIVARERQEERDDALRRRARNAAGASSASDANVWTPADQAMVDGGDAFGPAGPTPVRTVGDKFRIIMAAASNGVDDLRGAIVQLARSGEIDDALVAILQGNAASAEEEGDAGRAKFMRKVAEACLREKEAAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2Q4</accession>
    <name>C1N2Q4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48382</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061915.1">
        <property type="nucleotide sequence ID" value="XM_003061869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2Q4"/>
    <dbReference type="GeneID" id="9687566"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48382"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="396"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="408" mass="45973" checksum="C5FCFEF75037F08D" modified="2009-05-26" version="1" fragment="single">VATAVVVAATAAVAVRPHPQRRAVRRERRPNGSERPLPPRARATARVHEGVGARVQSARESREGRERHAGRHARARRVDVAATARGGAGPGRGAPSRGGGGRARGDRGRRRRRAGAGVVRSRERAVARVRRDALAIARDEERFANSLRRRRVVVVVVVVAQVDDVRGRRRHSVLPRRGRERPRASLRGLGHERADIPRPADIRRRRDRRDGDDRRRRATQRRRERVDPAQPAPLPHERAAARRRRDVRDAPRGGQHRARPLSYVLEPSLPQVRAAVHPRHDHGVPDRSSRVELRADRRAAARLAVVVEPAVDLRRRRSLALLRGGSRFRRRRRRRDRRGTPPRAHGVIGVLHRDVSLHVRDGRARDRSGEARVREVRDEDAAAVHDRRAVEDRQRAGATGQRGRLAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N351</accession>
    <name>C1N351_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_42116</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TACO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062318.1">
        <property type="nucleotide sequence ID" value="XM_003062272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N351"/>
    <dbReference type="STRING" id="564608.C1N351"/>
    <dbReference type="GeneID" id="9687989"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42116"/>
    <dbReference type="eggNOG" id="KOG2972">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EQKKCTN"/>
    <dbReference type="OrthoDB" id="2017544at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048300">
        <property type="entry name" value="TACO1_YebC-like_2nd/3rd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049083">
        <property type="entry name" value="TACO1_YebC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532:SF0">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20772">
        <property type="entry name" value="TACO1_YebC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="YebC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TACO1/YebC-like N-terminal" evidence="3">
        <location>
            <begin position="53"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="TACO1/YebC-like second and third" evidence="2">
        <location>
            <begin position="130"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="276" mass="29217" checksum="F79307E019D23064" modified="2009-05-26" version="1">MSAFTVASSVASLASRASYALARVASRRASRAVASSPPSSRRPLTLSPVCMGRKAAKVAAKKQKGEAKRTKLYGKYGKLIVAAVKEGGGADPVSNTQLARVLADAARLSVPRELVDRNIKRATDGSQADYMELTYEAYGEGGVGIVIEVLSDNVNRAAADTKATINKNGGKVAEPGSGAFYTLEENVFEVACENGGDDVVPREDGEDGFTIYTEVQGFMQCQRALGDAGFEINPDETALKMIPLASVEVSDEAAEVNEALVEKLLELEDVDAVYTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3G6</accession>
    <name>C1N3G6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52164</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062608.1">
        <property type="nucleotide sequence ID" value="XM_003062562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3G6"/>
    <dbReference type="STRING" id="564608.C1N3G6"/>
    <dbReference type="GeneID" id="9687814"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52164"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IRTCIDF"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF34">
        <property type="entry name" value="ABC1 ATYPICAL KINASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="1">
        <location>
            <begin position="141"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="1">
        <location>
            <begin position="455"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="634" mass="70451" checksum="7224B541D901083B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3N7</accession>
    <name>C1N3N7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52243</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062647.1">
        <property type="nucleotide sequence ID" value="XM_003062601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3N7"/>
    <dbReference type="GeneID" id="9688087"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52243"/>
    <dbReference type="OMA" id="HAKDARE"/>
    <dbReference type="OrthoDB" id="10688536at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="721" mass="74031" checksum="94746E85E90F9D27" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N414</accession>
    <name>C1N414_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52372</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062714.1">
        <property type="nucleotide sequence ID" value="XM_003062668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N414"/>
    <dbReference type="GeneID" id="9688154"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52372"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="202" mass="22477" checksum="A7C4D29BCA9527AA" modified="2009-05-26" version="1">MALRRDDDDDEKTAEPEARRHQVRSIHWWRGVAKKRGLSSSSSSSTVFTRATRAALDADWDAEDEDEIEREWRALGVGAGPPGWYRQPFLGVRGGDDEKFRQTLASAGRYRPTESDDAARASATRAKETARAMEAAEALARKRGENVRRSAAFRRVLSHAGPHAAASARCTPTLENFCRRSCLSAHPSVSIPTHLDAFQLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N426</accession>
    <name>C1N426_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_52383</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TDE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062471.1">
        <property type="nucleotide sequence ID" value="XM_003062425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N426"/>
    <dbReference type="STRING" id="564608.C1N426"/>
    <dbReference type="GeneID" id="9688161"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52383"/>
    <dbReference type="eggNOG" id="KOG2592">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DKHCNPL"/>
    <dbReference type="OrthoDB" id="5963193at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005016">
        <property type="entry name" value="TDE1/TMS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383">
        <property type="entry name" value="SERINE INCORPORATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383:SF9">
        <property type="entry name" value="SERINE INCORPORATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03348">
        <property type="entry name" value="Serinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="328"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="442" mass="46420" checksum="444B6E2AC72E814C" modified="2009-05-26" version="1">MAAACAGSACMTATCGCLGHVGDAVAKTSARALYVVMFAISTALAFVMRDCAQPLLKRIPWIARLATMNYAVYRISLGNFIFFGAMACALVGVKRRSDARDVHLHHGSWVLKFTAWALCNVLPFFASNGVVGAYTWVARVASGVFLVVQMIILLDFAFFWNESWVARQHAGWLVGLLVSTIVLYAESVAVVVMAFRWFSPRGVDCGSNDWMIGSACALCLAFSLACVHPGVKARSRVVTLDGSLLPSAVVTSYCTYLLYSALASEPSEYECNPRGSETGAGAGSRGGVAEIASTALTLASVAYGALRAGSADFFGGVDGDGDDGDGDGGVDASALLGGGGDGGGSDSDDEENGGVGARGKASYPSGPVSYNYAFFHFIFALASAYLAMLMTGWGDRAFEDGGAPVDVGWASVYVKYASLWVTGLLYTWSLVAPAVMPDRDWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5K9</accession>
    <name>C1N5K9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63696</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063176.1">
        <property type="nucleotide sequence ID" value="XM_003063130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5K9"/>
    <dbReference type="GeneID" id="9688820"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63696"/>
    <dbReference type="OMA" id="WPPESEH"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="281" mass="25930" checksum="1D0BDF62ED8F14A1" modified="2009-05-26" version="1">MPHSLALGAATSGAAGPPPVPLFAATTTSAGGSAGGGRGGGRGGRGDGGGGGGGGRDAHSPMPPGTAAAVQAQERAEAEGECEAREGEAGAPPGPGGMDIGGAAYGMDDGDGDDEEHGYAPALSEGFSGGFSGDAMIDGGVDTGGGGHGGEINSEDGVAMQGGGVSGGGGSVGGGLGSGGGGGSGGNQNHRGARGGGGDDGDGGGARGAVSGAGARGADLGPDAAGPVGTGPSGGGADGGGEDERDRDGENQREQQTLEGHQVRSIHRSPYDRVRVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5M9</accession>
    <name>C1N5M9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_42665</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063185.1">
        <property type="nucleotide sequence ID" value="XM_003063139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5M9"/>
    <dbReference type="STRING" id="564608.C1N5M9"/>
    <dbReference type="GeneID" id="9688831"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42665"/>
    <dbReference type="eggNOG" id="KOG0610">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ASTHRVC"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="277" mass="29814" checksum="3A4BF5078D3623CD" modified="2009-05-26" version="1">MLPTFVDAFVARDDDDDDDDASPSSFVACVVSRRHGDGATLASLLDVARAAAGTGAPLGLPELQARHLASQLALALDALHRVAAIVHGDVKPENALVDRAHRIQLCDFDLATSTSRPAVADAEDDLAEENDEDEYLYAFCGTAEYLAPETIAGAPRSAARDWWALAITMYELVHGKTPFASSRGNDEVTMRRVRTARIDWPDPPGVSDACRGVISAMLRRQPSTSGGGEWDVSARLCGERGLEDLKRASFFRGVDWDRVGLDPPASTKGWVVLPQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5X6</accession>
    <name>C1N5X6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_53082</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063439.1">
        <property type="nucleotide sequence ID" value="XM_003063393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5X6"/>
    <dbReference type="STRING" id="564608.C1N5X6"/>
    <dbReference type="GeneID" id="9688675"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53082"/>
    <dbReference type="eggNOG" id="KOG0710">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1245404at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="215"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="111"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="370" mass="41374" checksum="0BBFCFC53ED4B3AC" modified="2009-05-26" version="1">MLSAVSSVSSARARFPAVARTFRSARARQVALHTRASSAEQARARPRAPPPSSRASFPFRSRVAWRRARYDDASPEDARLDAPRSLFFFPASAAYVYVYALGLADAVSSPFPASSSSASSSSSSSLSQQKSEQKVQEQQQPQQKPPQQTPRYSREYARNPYARFSMSPDPWNELAQLMEMRIPRRFLTPGLLGGDMGTGSSLGAGPIPHRDSVGRLPNNFDFNMNIIETKKGYEFTADLPGLSKDMVNVELDTDNDMLMISAERAERHEEVRPPEDFRDVTESRGTFLVHEIHPDVPEDEDKDSGFKFHVYERSYGKYQRQFRMPENSISDPGKLDVTLKNGVLTVKVPKKPDAIDKADKKNLKKIAIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6W6</accession>
    <name>C1N6W6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PAF1 complex protein Rtf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_53466</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063625.1">
        <property type="nucleotide sequence ID" value="XM_003063579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6W6"/>
    <dbReference type="STRING" id="564608.C1N6W6"/>
    <dbReference type="GeneID" id="9689066"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53466"/>
    <dbReference type="eggNOG" id="KOG2402">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ISGCYAR"/>
    <dbReference type="OrthoDB" id="166375at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990269">
        <property type="term" value="F:RNA polymerase II C-terminal domain phosphoserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.200">
        <property type="entry name" value="Plus-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004343">
        <property type="entry name" value="Plus-3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036128">
        <property type="entry name" value="Plus3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13115">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13115:SF8">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03126">
        <property type="entry name" value="Plus-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00719">
        <property type="entry name" value="Plus3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159042">
        <property type="entry name" value="Plus3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51360">
        <property type="entry name" value="PLUS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Plus3" evidence="6">
        <location>
            <begin position="223"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="80"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="515"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="517"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="636" mass="69458" checksum="1E5A2A0C546BD0B7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6Z8</accession>
    <name>C1N6Z8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48959</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063642.1">
        <property type="nucleotide sequence ID" value="XM_003063596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6Z8"/>
    <dbReference type="STRING" id="564608.C1N6Z8"/>
    <dbReference type="GeneID" id="9689259"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48959"/>
    <dbReference type="eggNOG" id="ENOG502QRNX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QNASNMD"/>
    <dbReference type="OrthoDB" id="440455at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31245:SF20">
        <property type="entry name" value="F18B13.13 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31245">
        <property type="entry name" value="UBIQUITIN SYSTEM COMPONENT CUE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="326" mass="34243" checksum="C84E9D7488FCCA68" modified="2009-05-26" version="1">MADVCQMAPAVLSPISPNESRKRRHGHGYGPGGEDAAPSTWFKRHRTGASFARRLLHLRGFAVDVRRAEDIVRFLDQFPPELDKDVSRILEKCADVDDAEKQLTALRLTFSASGGERGGDAPAAGVEAVASAAAAARDDGDARATATATATAAEGGGAANASTSAALKAAGGAADAIGDPADGVVLSGEWVGALVNEMSASADVPDAHERGTRVLRAFETAVRNAVAHAAEGGAGRARAPPREGSESAGNNAEEQAAERRRVADENVILKRGLNIQTQRVEQLTRACATLQEQMTQLQRNNYSLSVHLKEAMRSRGGAFDRQPDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N700</accession>
    <name>C1N700_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65834</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063819.1">
        <property type="nucleotide sequence ID" value="XM_003063773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N700"/>
    <dbReference type="GeneID" id="9689260"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65834"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="217" mass="25309" checksum="866A10572B780F0D" modified="2009-05-26" version="1">MRSLQRRPVHVVRLLQRRRLHSNLVQDGRAVRALFHDRLRGGGGQRRGLLLEQTGRVFFRLRGGFLRSSLRVFARSRQLCGQRRDSPLRFFNLGRESLDLFAACSAATACSVRAPRSTTQLASSSAWYTMALYVPDHSLSSCERTRECVRRRARGREFRLKTREERTIPEEEAEEEKNVVRRFRRRRRRRPAATRPALRSRAKLSNARPRGRFVLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N788</accession>
    <name>C1N788_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_65908</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063855.1">
        <property type="nucleotide sequence ID" value="XM_003063809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N788"/>
    <dbReference type="STRING" id="564608.C1N788"/>
    <dbReference type="GeneID" id="9689136"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65908"/>
    <dbReference type="eggNOG" id="KOG0817">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DHRANGH"/>
    <dbReference type="OrthoDB" id="548600at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119:SF0">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="385"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="418"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="172"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="307"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="462" mass="47566" checksum="A3BD959FB56BCBC0" modified="2009-05-26" version="1">MQRVMAAASASASAASRRGGSQGQGGTRGAGAGAGAGERLELFAGLDDETAAAAAAALAHGYAVDDVMRVSRRAQRRKLQKEKYMQKLRHGFDAVSAEETTRRAAAARRNAFSETDRFGPRRGGGGGGGAGSPGGFDYDFGGGGRGVERGFGTEVDRRGASRMAARAAVAAEFKARGSSGGGGGGDADGGGSRGRSGRGRRSGDGGSSANSPSGGSAGTLGSPSTPNAGGIPSPSPMNPGFNAMNPMGLMNNPMGMLSPMLGMHPMMNPAMAGMMMQQQQQQQQMMAQMMSQQFNAMNFAATGGGGGFNPQFQSMMHPAQQQAYHGQPPSPPSRQNQNQNQRPSPPQRGSERVAEVFALVASNSWEEVVALVDSDAVDVDLADARGNTLFMAAASRGHKRLSKRLMKRGAGVNKQNADGQTALHYCLAFGHDALGDYLLAKGADASVANKHGLTPFDGLVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7J7</accession>
    <name>C1N7J7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_43116</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063745.1">
        <property type="nucleotide sequence ID" value="XM_003063699.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N7J7"/>
    <dbReference type="GeneID" id="9689355"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43116"/>
    <dbReference type="eggNOG" id="KOG1805">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="306218at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014808">
        <property type="entry name" value="DNA_replication_fac_Dna2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08696">
        <property type="entry name" value="Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Dna2 N-terminal" evidence="8">
        <location>
            <begin position="427"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="9">
        <location>
            <begin position="1090"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="194"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="339"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="666"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="235"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="669"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1339" mass="136264" checksum="EC57EB1CF374EDB3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7J9</accession>
    <name>C1N7J9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_49035</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063746.1">
        <property type="nucleotide sequence ID" value="XM_003063700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7J9"/>
    <dbReference type="STRING" id="564608.C1N7J9"/>
    <dbReference type="GeneID" id="9689356"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49035"/>
    <dbReference type="eggNOG" id="KOG2038">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RSCWWEL"/>
    <dbReference type="OrthoDB" id="28947at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040155">
        <property type="entry name" value="CEBPZ/Mak21-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048">
        <property type="entry name" value="CCAAT-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048:SF0">
        <property type="entry name" value="CCAAT_ENHANCER-BINDING PROTEIN ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="499"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="376"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="602"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="821"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="981"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="609"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="645"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="833"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="872"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="985"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1027"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1064"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1083"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1135"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1152"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1178"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1212"/>
            <end position="1223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1230" mass="131942" checksum="52C4B6DDD189848C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7R1</accession>
    <name>C1N7R1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_7703</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064137.1">
        <property type="nucleotide sequence ID" value="XM_003064091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7R1"/>
    <dbReference type="STRING" id="564608.C1N7R1"/>
    <dbReference type="GeneID" id="9689578"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7703"/>
    <dbReference type="eggNOG" id="KOG0929">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GIASMHE"/>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="2">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="155" mass="17082" checksum="C9F8A71CD0243D92" modified="2009-05-26" version="1" fragment="single">DVANFLLRTKGLDKAAVGELLGGHDDESVAVMRAFARSFDFSKLDFDVALRVFLKPFRLPGEAQKIDRLMEAFAARYCACNDGAFANTDAAYVLAFAVIMLNTDAHNDAMDGKLTRDEFAAMARSAESGGDVDDAMLHTLYDRVVKDEIKFTDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7S5</accession>
    <name>C1N7S5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53810</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063960.1">
        <property type="nucleotide sequence ID" value="XM_003063914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7S5"/>
    <dbReference type="GeneID" id="9689401"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53810"/>
    <dbReference type="OMA" id="MNFIKET"/>
    <dbReference type="OrthoDB" id="498375at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="120" mass="12768" checksum="11E80AA360BF6CC1" modified="2009-05-26" version="1">MWDEVEELSQAASDKKPAPAEMDPVPISEKDMNFIKETQAALAAAKKGAESVDVDTLRSLESAAASAKKVTVSNARLDSLTKALDQALEAAKACTGDDCAIEWETVEEISQAKSRAQNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8G4</accession>
    <name>C1N8G4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_43323</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064262.1">
        <property type="nucleotide sequence ID" value="XM_003064216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8G4"/>
    <dbReference type="STRING" id="564608.C1N8G4"/>
    <dbReference type="GeneID" id="9689521"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43323"/>
    <dbReference type="OrthoDB" id="10035764at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002870">
        <property type="entry name" value="Peptidase_M12B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01562">
        <property type="entry name" value="Pep_M12B_propep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912393" evidence="3">
        <location>
            <begin position="25"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B propeptide" evidence="4">
        <location>
            <begin position="59"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="228" mass="24996" checksum="2739D6C29F563154" modified="2009-05-26" version="1">MARRAPPRALALLLLAFLVATCFARRVDARDLNVSSAAPSTPTAFLRDLDGDYEITRVTRRPRHASSAPTPARYPARLALALDAFGTRYELDLRRHDALFHRDYRTWSVGADSSFAKVEGSHPNRNHCHYRGVVSNAVGESTVAMSLCKGVTAKIITQRERISLEPASAHLPGYESEWRPPSGDADGDADGDAEDADAFRHPDPLGRVPSHQSRRSPHDRVGVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8H1</accession>
    <name>C1N8H1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_49144</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064266.1">
        <property type="nucleotide sequence ID" value="XM_003064220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8H1"/>
    <dbReference type="STRING" id="564608.C1N8H1"/>
    <dbReference type="GeneID" id="9689524"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49144"/>
    <dbReference type="eggNOG" id="KOG2988">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LWRVHIG"/>
    <dbReference type="OrthoDB" id="1928736at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000001">
        <property type="entry name" value="60S ribosomal protein L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039109">
        <property type="entry name" value="Ribosomal_eL30-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022991">
        <property type="entry name" value="Ribosomal_eL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002172">
        <property type="entry name" value="PRK01018.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11449">
        <property type="entry name" value="RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00709">
        <property type="entry name" value="RIBOSOMAL_L30E_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00993">
        <property type="entry name" value="RIBOSOMAL_L30E_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="4">
        <location>
            <begin position="18"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="115" mass="12635" checksum="2EF17171AAA9C493" modified="2009-05-26" version="1">MSAVEVTKKKKGKGNDGINNRLQIVMRSGKYSLGYKTTLKTLRSGKSKLVIISNNCPPLRKSEIEYYAMLAKTGVHHYAGNNVDLGTSCGRYYRVSCMSITDPGDSDIIKAMPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8R5</accession>
    <name>C1N8R5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine synthetase, catalytic domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GLN</name>
        <name evidence="4" type="ORF">MICPUCDRAFT_30309</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064321.1">
        <property type="nucleotide sequence ID" value="XM_003064275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8R5"/>
    <dbReference type="STRING" id="564608.C1N8R5"/>
    <dbReference type="GeneID" id="9689762"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30309"/>
    <dbReference type="eggNOG" id="ENOG502QQE3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VKWETYT"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1560">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040577">
        <property type="entry name" value="Gln-synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052725">
        <property type="entry name" value="GS_Type-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022147">
        <property type="entry name" value="GSIII_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42974">
        <property type="entry name" value="GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42974:SF1">
        <property type="entry name" value="TYPE-3 GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18318">
        <property type="entry name" value="Gln-synt_C-ter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12437">
        <property type="entry name" value="GSIII_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="3">
        <location>
            <begin position="166"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="682" mass="74576" checksum="FD2E90BFBEB00989" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N952</accession>
    <name>C1N952_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Intracellular chloride channel family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_43479</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064392.1">
        <property type="nucleotide sequence ID" value="XM_003064346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N952"/>
    <dbReference type="GeneID" id="9690000"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43479"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31535">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31535:SF3">
        <property type="entry name" value="REGULATORY PROTEIN ZESTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="519" mass="51681" checksum="BE1B6E36C38CF4B6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9G2</accession>
    <name>C1N9G2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_54493</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064447.1">
        <property type="nucleotide sequence ID" value="XM_003064401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9G2"/>
    <dbReference type="GeneID" id="9689888"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54493"/>
    <dbReference type="OrthoDB" id="1896656at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044559">
        <property type="entry name" value="WOX13-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46777">
        <property type="entry name" value="WUSCHEL-RELATED HOMEOBOX 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46777:SF5">
        <property type="entry name" value="WUSCHEL-RELATED HOMEOBOX 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="4">
        <location>
            <begin position="505"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="507"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="205"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="347"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="490"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="571"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="358"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="599" mass="63452" checksum="1A67297B18BB6868" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9M6</accession>
    <name>C1N9M6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ubiquitin associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_54544</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DDI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH50972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064638.1">
        <property type="nucleotide sequence ID" value="XM_003064592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9M6"/>
    <dbReference type="STRING" id="564608.C1N9M6"/>
    <dbReference type="GeneID" id="9690205"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54544"/>
    <dbReference type="eggNOG" id="KOG0012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GHRLNAF"/>
    <dbReference type="OrthoDB" id="1047367at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05479">
        <property type="entry name" value="RP_DDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14309">
        <property type="entry name" value="UBA_scDdi1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01796">
        <property type="entry name" value="Ubl_Ddi1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057273">
        <property type="entry name" value="Ddi1/2_HDD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033882">
        <property type="entry name" value="DDI1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019103">
        <property type="entry name" value="Peptidase_aspartic_DDI1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12917">
        <property type="entry name" value="ASPARTYL PROTEASE DDI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12917:SF1">
        <property type="entry name" value="AT13091P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09668">
        <property type="entry name" value="Asp_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24669">
        <property type="entry name" value="Ddi2_HDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="9">
        <location>
            <begin position="391"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH50972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="434" mass="45213" checksum="FED7A3F4A0424F3A" modified="2009-05-26" version="1">MHVTVTTEDDAIVTVDVDPATVVENLKAILEAETDVPTREQVLLFNGGELANDDVLSAKNVGEGDLLMLLRKRGGGGGGVGAAANGANDNPTAMRPDGSAVDPAAFQRAIRADAHAMQSLRANNPSLHGAILNDDPSAMQQMLRDAATARKRAEDARQAEIDLLNADPFDLDAQRKIEEAIRQKNVDENFETAMETTPEAFGSVIMLYVDMEVNGHALKVFVDSGAQMTIMSLGCAIRLGLERLIDKRWRGVAKGVGTQKIIGRVHQAPITVAGSMMPCAITVLEKEQDMDFIFGLDMLRRHQCQIDLKDNVLRLGTIEKAIPFYTLAIPFLGESELPSFAKAMGEPEPEEAAGGAAAAAAAAAAAGGGGGVGGGGGGAAAAPAPAGGGGGGDAEGKVAKLMELGFDRAKCVEALQACGWNEEHAASLLFSGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9S9</accession>
    <name>C1N9S9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_37150</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS26 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064668.1">
        <property type="nucleotide sequence ID" value="XM_003064622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9S9"/>
    <dbReference type="STRING" id="564608.C1N9S9"/>
    <dbReference type="GeneID" id="9690109"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37150"/>
    <dbReference type="eggNOG" id="KOG3063">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FKWKFSS"/>
    <dbReference type="OrthoDB" id="3821113at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000015">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="305" mass="33924" checksum="10FFFFBBBFBA9BA9" modified="2009-05-26" version="1">MDFFGLGPTVTVGATFAEPSDASSTRTVSVKSDASSGGVATTPTRLYTTGDTIAGAITLTTPPGSKVDHLGVKVEVLGQIEMGFDRGHAWDFVALAREARPAGDLIGVTEIPFVFKDVEMPHESYEGINARCRYVVRTTVTRTYGGTVTHDLPFVVRNVSVPPENDAAIKMEVGIEDCLHIEFEYAKAKYHLRDCVVGKIHFLLVRIKIKHMELEIRRRESTGAGANTYNESETVAKFEVMDGAPVKGETAPVRLFLSPYDLTPTYKNVANRFNVKYYLNLVLVDEEDRRYFKQQEIFLYRDALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9T7</accession>
    <name>C1N9T7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_49292</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064791.1">
        <property type="nucleotide sequence ID" value="XM_003064745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9T7"/>
    <dbReference type="STRING" id="564608.C1N9T7"/>
    <dbReference type="GeneID" id="9690113"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49292"/>
    <dbReference type="eggNOG" id="ENOG502QTX0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VQDGRYC"/>
    <dbReference type="OrthoDB" id="10262255at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039341">
        <property type="entry name" value="CFAP99"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34649">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34649:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="349"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="810"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="516"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="675"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="748"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="814"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="846" mass="96059" checksum="C1998C115D9E009F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9U8</accession>
    <name>C1N9U8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54642</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064678.1">
        <property type="nucleotide sequence ID" value="XM_003064632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9U8"/>
    <dbReference type="GeneID" id="9690119"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54642"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="101" mass="10759" checksum="B3994368CCC37D9B" modified="2009-05-26" version="1">MEHDVGRRLEDAVAVVASTAAAVVMDDDDDDDVTDDRPGKEGRWVVVGGDDGELTRVRAREGAPAAAERDGALAAESDDPKVRSISHWSPYDRVGDVDADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRB7</accession>
    <name>C1KRB7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Photosystem I assembly protein Ycf3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ycf3</name>
        <name evidence="7" type="ORF">MicpuC_chl12</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="7"/>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Seems to be required for the assembly of the photosystem I complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast thylakoid membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Ycf3 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRB7"/>
    <dbReference type="STRING" id="564608.C1KRB7"/>
    <dbReference type="OMA" id="VYYRDGM"/>
    <dbReference type="OrthoDB" id="431027at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00439">
        <property type="entry name" value="Ycf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022818">
        <property type="entry name" value="PSI_Ycf3_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002725">
        <property type="entry name" value="PRK02603.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 5 6" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR 1" evidence="5">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR 2" evidence="5">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR 3" evidence="5">
        <location>
            <begin position="120"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACO50749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="166" mass="19234" checksum="0A54BB88B8562A77" modified="2009-05-26" version="1">MPRSQRNDNFIDKTFTVIADILLKVLPTTRNEKEAFIYYRDGMSAQAEGEYAEALQNYYQAMRLEVDPYDRSYIFYNIGLIHTSNGEHTKALEYYYQALDRNPALPQALNNIAVIYHYRGEQALESGNIPDSETLFGKAAEYWKEAIRLAPLNYSEAQNWLQTTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGR5</accession>
    <name>C1MGR5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_46128</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055365.1">
        <property type="nucleotide sequence ID" value="XM_003055319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGR5"/>
    <dbReference type="GeneID" id="9680622"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46128"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="entry name" value="PGBD-like superfamily/PGBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="PGBD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidoglycan binding-like" evidence="3">
        <location>
            <begin position="73"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="516"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="576" mass="59678" checksum="9F1042EB8B15493D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHE9</accession>
    <name>C1MHE9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_50152</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055478.1">
        <property type="nucleotide sequence ID" value="XM_003055432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHE9"/>
    <dbReference type="GeneID" id="9681192"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50152"/>
    <dbReference type="eggNOG" id="ENOG502SABS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YDGPYSM"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="6">
        <location>
            <begin position="74"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="322" mass="35640" checksum="CBB1AEB58FCEB731" modified="2009-05-26" version="1">MPSKLARGIPRRVRYDGPYSMNLRDPARFARTLLVNALVWEVPRVLVGFAYRRRYRATCGKGGKHAEFAALAPSHVMSFVHAVVISVLGLFIMRETWNYPIYDKFYVNDRWADPSRFTLNVIELTNWLFFGYMTDDLAHVLVKYPKLGKADMVAHHLVFIACAILAGGTQSFLFPFSWLLAGELSTPLLALRWFIRTLAGLDSPTLAAVATRMNLLQSRRDADADADADAEAKTATAKEAAGALEAAVTKTFVFVFFVVRVCVFGAGLAHTLRFHAAHAAVPAGARAAIMSILLAGAGLNAFWFRLMIVKVLGFGGKREKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHF2</accession>
    <name>C1MHF2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46219</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055481.1">
        <property type="nucleotide sequence ID" value="XM_003055435.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MHF2"/>
    <dbReference type="GeneID" id="9680328"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46219"/>
    <dbReference type="OMA" id="DGANDEF"/>
    <dbReference type="OrthoDB" id="988602at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17745">
        <property type="entry name" value="BRCT_p53bp1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047249">
        <property type="entry name" value="BRCT_p53bp1-like_rpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711:SF1">
        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="1181"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="783"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1056"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="573"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="791"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="806"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="829"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="915"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="928"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="952"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1062"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1162"/>
            <end position="1175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1435" mass="148129" checksum="C130649B0574C116" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHJ5</accession>
    <name>C1MHJ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_12662</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBCE family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054964.1">
        <property type="nucleotide sequence ID" value="XM_003054918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHJ5"/>
    <dbReference type="STRING" id="564608.C1MHJ5"/>
    <dbReference type="GeneID" id="9680689"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12662"/>
    <dbReference type="eggNOG" id="KOG3207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SEESHMF"/>
    <dbReference type="OrthoDB" id="5273213at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd17044">
        <property type="entry name" value="Ubl_TBCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044079">
        <property type="entry name" value="Ubl_TBCE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46545">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46545:SF1">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CAP-Gly" evidence="7">
        <location>
            <begin position="27"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="528" mass="56923" checksum="5087D082585CB64B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHL7</accession>
    <name>C1MHL7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_8359</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055513.1">
        <property type="nucleotide sequence ID" value="XM_003055467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHL7"/>
    <dbReference type="STRING" id="564608.C1MHL7"/>
    <dbReference type="GeneID" id="9681024"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8359"/>
    <dbReference type="eggNOG" id="KOG0126">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAPKPQI"/>
    <dbReference type="OrthoDB" id="2573941at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12411">
        <property type="entry name" value="RRM_ist3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051847">
        <property type="entry name" value="RNA_proc/Spliceosome_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045844">
        <property type="entry name" value="RRM_Ist3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880:SF1">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="104" mass="11592" checksum="87E5FB788325C3F4" modified="2009-05-26" version="1" fragment="single">QIRLGLSEGASWHAKYKHSAYVFAGGLSFDLTEGDVLAVFSQYGEIVDVNLVRHEDTGKSRGFAFICYEDQRSTVLAVDNLNGAKVLGRIIKVDHVEDYKLKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHP4</accession>
    <name>C1MHP4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50273</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054990.1">
        <property type="nucleotide sequence ID" value="XM_003054944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHP4"/>
    <dbReference type="GeneID" id="9680835"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50273"/>
    <dbReference type="OMA" id="FVMAPRV"/>
    <dbReference type="OrthoDB" id="531380at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="341" mass="35787" checksum="98E3876E3E0A39C8" modified="2009-05-26" version="1">MATTARLAHAGSFHRANPASHSRRSTRDRDIATRAADADASTTENARGATADDSGASRRRTPLERVANDPLTAFVMAPRVALGGATEALDLLQSGELFGVAARFPAELNTLMQDPRPPQDKAAELLRRAEEITEMLEERGIVAEAPGRELLKPMVPVELFDRYLDPEVVRASTSSPTETETETAAAAGTTATTYAAEPPTAETLTDTAAPPAKDDAAGGDANVDSIEDAYAFMRDQRKVGDVEDEDDPAVLAAAADVAAALKREAGAGKMPNENVASEEVGEAAVPPPTPSPPPPPPTPTTTAPFDVPQELDVWGIVKSAEELTADIVMSQSKATATATKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHS2</accession>
    <name>C1MHS2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_50302</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055003.1">
        <property type="nucleotide sequence ID" value="XM_003054957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHS2"/>
    <dbReference type="GeneID" id="9681110"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50302"/>
    <dbReference type="eggNOG" id="ENOG502SASC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FFKFAPW"/>
    <dbReference type="OrthoDB" id="201321at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="4">
        <location>
            <begin position="127"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="257" mass="26613" checksum="E9B956D6F562C145" modified="2009-05-26" version="1">MAAAAPTARFAAPLPPRASAPAPARRARAHARASSSSASASADVAALKKDLLAAVAASRKPGADPSATKRAILDATDALESIADDVPFLDVSGRWSLVYSTSDASSALGPLQAVLDDDAFQKLVDTLYKTFFTFLPSLAGSAETGARGVANQQMVDIENGRVVNVVDVELAFGGAVRVGVMGTIEAKDPDAREVVVTFTDWEIGPAPGLSDGGAGEQPRVRLPLPRPKGALKNTFCDETLRISRGGRGGVFITSRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHT3</accession>
    <name>C1MHT3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50312</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055009.1">
        <property type="nucleotide sequence ID" value="XM_003054963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHT3"/>
    <dbReference type="GeneID" id="9681115"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50312"/>
    <dbReference type="OMA" id="FWEAMAN"/>
    <dbReference type="OrthoDB" id="10660188at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="962"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="983" mass="107416" checksum="25986A645F85900B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI29</accession>
    <name>C1MI29_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_50414</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055059.1">
        <property type="nucleotide sequence ID" value="XM_003055013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI29"/>
    <dbReference type="STRING" id="564608.C1MI29"/>
    <dbReference type="GeneID" id="9681161"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50414"/>
    <dbReference type="eggNOG" id="KOG2149">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MFAWFIL"/>
    <dbReference type="OrthoDB" id="361362at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024679">
        <property type="entry name" value="Ipi1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057949">
        <property type="entry name" value="TPR_TEX10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16056">
        <property type="entry name" value="REGULATOR OF MICROTUBULE DYNAMICS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16056:SF2">
        <property type="entry name" value="TESTIS-EXPRESSED PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12333">
        <property type="entry name" value="Ipi1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25781">
        <property type="entry name" value="TPR_TEX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-rRNA-processing protein Ipi1 N-terminal" evidence="5">
        <location>
            <begin position="145"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="TEX10-like TPR repeats" evidence="6">
        <location>
            <begin position="702"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="209"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="323"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="604"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="216"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="610"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1106" mass="110712" checksum="3EE8098B1EFCEE55" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI38</accession>
    <name>C1MI38_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_38012</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the hemerythrin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055062.1">
        <property type="nucleotide sequence ID" value="XM_003055016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI38"/>
    <dbReference type="GeneID" id="9681167"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38012"/>
    <dbReference type="eggNOG" id="ENOG502S8FB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FQAQLGC"/>
    <dbReference type="OrthoDB" id="568338at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12107">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.50">
        <property type="entry name" value="Hemerythrin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035938">
        <property type="entry name" value="Hemerythrin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012827">
        <property type="entry name" value="Hemerythrin_metal-bd"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47188">
        <property type="entry name" value="Hemerythrin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="140"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="358" mass="38191" checksum="79BFD89382308EB6" modified="2009-05-26" version="1">MDLTGKHMPDFHVKTFGADGAIARLPLRDWATRAYASREVRFVAVCVEGGGRAERVGREFQRSYFDGTSVVNGFVDDDDDFPRFPCQLGCQGLVVVDARGRFATLRSPAYLEHREAAYDAVERMLEPLIAAAETRRRAAKAPRLDVDVDMDPPGTPERNLAPGEASSASDASASASATDATRASPSSPDATSTAPPRQVARFSKHACKGDAHALDDDDDDATASFEIPAVGVDVVDDEHDELHALLKTALATRSPRDVLSLGSAFATHATHEEALMRASGFADGEGAFSAAASHAKDHDRLVASATTAATTLEEDGKVAAAAIRHLGRSIIEHAVTFDASYAAFVAEKRRREETARTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI69</accession>
    <name>C1MI69_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_38033</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the RING-type zinc finger family. ATL subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055616.1">
        <property type="nucleotide sequence ID" value="XM_003055570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI69"/>
    <dbReference type="STRING" id="564608.C1MI69"/>
    <dbReference type="GeneID" id="9680384"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38033"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SICCEET"/>
    <dbReference type="OrthoDB" id="515079at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053238">
        <property type="entry name" value="RING-H2_zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14155:SF610">
        <property type="entry name" value="OS01G0755700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14155">
        <property type="entry name" value="RING FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="294"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="126"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="349"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="383" mass="40093" checksum="E4229BE3846504E1" modified="2009-05-26" version="1">MPARRVLDHGAREYVDRVVDAFGVTRAPPPPPPPPYAASGGGDASAKHAANIVGVSGYLLLAVAALFVCVHCCRFGTCRDESATEEGLLRAAAARRAARRRRRRLARGGPPEPYAGADDPRAASAELAARGGRQQQQQQQRQPRSLLARWRREAAESQATRASRARGGDGRSGRPRRGQSAGAGALQGGGGDGGDGGSTTDDEEYDRAVLAAARGPTGDEPRPATRGIIASLPRCYVGDDKWRARMGMVPAAAAAAAAAAAAAAAGAGSGPGKGFDFITSVALAEAYDAERDTCSICCEETEPGDEIVVLTCAHAFHDECMTPWLRVKLECPVCRHLVERVSRKDARAVFSPPPTSRAGEGGGREGDAAHVAVDVEDEERARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIT8</accession>
    <name>C1MIT8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_31102</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055720.1">
        <property type="nucleotide sequence ID" value="XM_003055674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIT8"/>
    <dbReference type="STRING" id="564608.C1MIT8"/>
    <dbReference type="GeneID" id="9681001"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31102"/>
    <dbReference type="eggNOG" id="KOG0084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IPHVEIS"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01869">
        <property type="entry name" value="Rab1_Ypt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000359">
        <property type="entry name" value="Small GTP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057289">
        <property type="entry name" value="Rab1/Ypt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="204" mass="22725" checksum="C804B6FEFBA2168D" modified="2009-05-26" version="1">MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTVDLEGKTVKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLNEIDRYANENVNKLLVGNKSDLTAKKVVDYQTAKAFADEIGIPFLETSAKNATNVEEAFMKMAGEIKNRMASQPALNNGPKGATVRPGEGRPVNANKSNCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIV1</accession>
    <name>C1MIV1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_61724</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055198.1">
        <property type="nucleotide sequence ID" value="XM_003055152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIV1"/>
    <dbReference type="STRING" id="564608.C1MIV1"/>
    <dbReference type="GeneID" id="9681040"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61724"/>
    <dbReference type="eggNOG" id="KOG1501">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VVYKRPT"/>
    <dbReference type="OrthoDB" id="412876at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF4">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="482"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="489"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="823" mass="90910" checksum="D9F19DDB19EC3554" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ58</accession>
    <name>C1MJ58_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_12286</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055256.1">
        <property type="nucleotide sequence ID" value="XM_003055210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ58"/>
    <dbReference type="STRING" id="564608.C1MJ58"/>
    <dbReference type="GeneID" id="9680906"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12286"/>
    <dbReference type="eggNOG" id="KOG0032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THGICHR"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="47"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="349"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="385"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="421"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="458"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH60508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="492" mass="55129" checksum="E6617589A072F1A8" modified="2009-05-26" version="1" fragment="single">RPQDPNKRVGAAKDGPVGPKPIPNAKGTFTRQGSVLGRETEDINEHYKFHNELGKGAYGTTFLVSHKVTGKKYACKSISKRKLISKDEIDDVRREISVLHHLSGHPNIVGLVQAFEGSKHIYIVMDLCTGGELFDRIVERGNYTEQDAAAVFRTMIKSCQYWHSLGVVHRDLKPENFVLKTKDYDAPIMAIDFGLSAYWEPGQPPMDIFCGSAFYMAPEIFNKKYDAGVDIWACGVILYILLSGGPPFIADTDKGIQDMILACKYDLAASRWPKISASAKDLIRKMLMKKPKDRLTAEEVLNHPWVREDGDAPATKIEDEVLSRMKNFSAMNKFKKLGLMAMARTMTKEEILGLKELFQSFDEDGSGTVTIKEFQKGLAKKGTSTTAAEVQQLLNTIDVDASGEIDYQEFIASTLSAAKFNSEENIARAFAYFDTDNSGYITVDELKKVIKENNVDVDATNFLDEVDKNNDGRVDYDEFLAMMTKEDKPKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJG1</accession>
    <name>C1MJG1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_50927</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055827.1">
        <property type="nucleotide sequence ID" value="XM_003055781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJG1"/>
    <dbReference type="GeneID" id="9680530"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50927"/>
    <dbReference type="eggNOG" id="ENOG502RZCC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DERVCAN"/>
    <dbReference type="OrthoDB" id="545589at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH61079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="181" mass="19763" checksum="0BFC7243F39A9F88" modified="2009-05-26" version="1">MASHVDVTLGSGAAPKLRRLSSCWRPASSGNLAALQDAHENGAPWDERVCANAARDGHLDVLIYAHENGCRWDARTCEYSAQNGHLECLKYARSNGCPWDEGLCAAAAKAGQLECLKWAREQGAPWGVMTPAFAAFAGDVDALRWVVENGCPWDKKTRDYAAMNNQEATLRWAIENGCPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJQ0</accession>
    <name>C1MJQ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55049</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056251.1">
        <property type="nucleotide sequence ID" value="XM_003056205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJQ0"/>
    <dbReference type="GeneID" id="9681881"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55049"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="202" mass="22250" checksum="1347C98CCE96472E" modified="2009-05-26" version="1">MADAENKPKKDKKKKEKRERGDGKVDERGVKSSKTSNPSKSAAAKKKKKPPSDAPSSAPPVAAAPVPVGKAARKRHLVRWFRDALADATDDAVRVDFLAARDYASVANVIRSRARALERRDASKSHAEAIRLLDNKGHFLNIVDQCVEKKEEEEASAAAAAVAETNRAHWENVKRRHRAKARPRPGSHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKB6</accession>
    <name>C1MKB6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H(+)-exporting diphosphatase</fullName>
            <ecNumber evidence="2">7.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_45236</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="2"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055966.1">
        <property type="nucleotide sequence ID" value="XM_003055920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKB6"/>
    <dbReference type="GeneID" id="9681939"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45236"/>
    <dbReference type="eggNOG" id="ENOG502QPJC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AEMSHMG"/>
    <dbReference type="OrthoDB" id="5210at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:diphosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001960">
        <property type="entry name" value="PRK00733.3-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="K(+)-INSENSITIVE PYROPHOSPHATE-ENERGIZED PROTON PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="451"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="513"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="543"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="623"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="734"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH59342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="770" mass="80850" checksum="7116A3A61093F961" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKF2</accession>
    <name>C1MKF2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_45244</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055986.1">
        <property type="nucleotide sequence ID" value="XM_003055940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKF2"/>
    <dbReference type="STRING" id="564608.C1MKF2"/>
    <dbReference type="MEROPS" id="T01.978"/>
    <dbReference type="GeneID" id="9681694"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45244"/>
    <dbReference type="eggNOG" id="KOG0183">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ICMLDHH"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03755">
        <property type="entry name" value="proteasome_alpha_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000004">
        <property type="entry name" value="Proteasome subunit alpha type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 3 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="4"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="222"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="251" mass="27600" checksum="E3BCC155E69F06AA" modified="2009-05-26" version="1">MSRYDGAITVFSPDGHLFQVEYALEAVRKGALAVGVRGKDTVVLGVEKKSLAKLQDPRSMKKIQLLDEHVCVAFAGLTADARILINRARLEAQNHRLTLEDAVSVEYITRYIGGVQQKYTQSGGVRPFGLSTLITGVSPEGKPQLFYTDPSGTFSEWKANATGRNSKALREWLEKNYSETSDVETVKLTLRALLELVEPSSKNIEIVVVSKSGIKTISNDVIDTFVRTIEEEKAAADKAKKENAQTVAQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKF3</accession>
    <name>C1MKF3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Transcription elongation factor 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_49426</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ELOF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056375.1">
        <property type="nucleotide sequence ID" value="XM_003056329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKF3"/>
    <dbReference type="STRING" id="564608.C1MKF3"/>
    <dbReference type="GeneID" id="9681494"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49426"/>
    <dbReference type="eggNOG" id="KOG3214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PFCNHKQ"/>
    <dbReference type="OrthoDB" id="445983at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.190:FF:000001">
        <property type="entry name" value="Transcription elongation factor 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007808">
        <property type="entry name" value="Elf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038567">
        <property type="entry name" value="T_Elf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934:SF0">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05129">
        <property type="entry name" value="Zn_ribbon_Elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH59751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="81" mass="9085" checksum="9049796DAC95F592" modified="2009-05-26" version="1">MGKRKSSKPPPKKVAPKIDTMFTCPFCNHDKAVIAKMDHLTEKGLVLCTICGQKFTSEITHLSEPIDVYSEWIDACEEANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKU7</accession>
    <name>C1MKU7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_31600</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056448.1">
        <property type="nucleotide sequence ID" value="XM_003056402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKU7"/>
    <dbReference type="STRING" id="564608.C1MKU7"/>
    <dbReference type="GeneID" id="9681366"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31600"/>
    <dbReference type="eggNOG" id="ENOG502QSWE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SMYSATY"/>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01951">
        <property type="entry name" value="lectin_L-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056573">
        <property type="entry name" value="Lectin_L-type_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019825">
        <property type="entry name" value="Lectin_legB_Mn/Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF19">
        <property type="entry name" value="LEGUME LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00307">
        <property type="entry name" value="LECTIN_LEGUME_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910515" evidence="2">
        <location>
            <begin position="24"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Legume lectin" evidence="3">
        <location>
            <begin position="25"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="304" mass="32719" checksum="6C8C494DC256A70F" modified="2009-05-26" version="1">MVLRYTAVSALLLIVAEFPVGCAGNFAFPDFSASRTVSLQGVSNRTRTWLRLTPSNPGVVGSAWYSTKQSIVGGFRTDFTFRITVDLDPTFPGPCKWVDHAPTSCSRRGGDGFAFVVQNHCSRALGGGGGGVGYSGIQNGIAVEFDTWFDADLRDPYENHIAVLTRGRDQIRSEHGSHLGVSLDIPDLANGERHDARIEYVPYLASESTGHSSFQAAPHLAKLVYPSASGQMQGLGSLRVYVDDMINPVLIVPVNVADFLDLDEGTAWAGFTSSTGVSFQNHDVLSWAFHEYVSGEAPRSITGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKX7</accession>
    <name>C1MKX7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PAC1</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_37319</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056462.1">
        <property type="nucleotide sequence ID" value="XM_003056416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKX7"/>
    <dbReference type="STRING" id="564608.C1MKX7"/>
    <dbReference type="MEROPS" id="T01.973"/>
    <dbReference type="GeneID" id="9681375"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37319"/>
    <dbReference type="eggNOG" id="KOG0178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YVLNDNM"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03752">
        <property type="entry name" value="proteasome_alpha_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000031">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="247" mass="27187" checksum="960948FBCAC0DDEE" modified="2009-05-26" version="1">MARRYDSHTTTFSPDGRLFQVEYAMEAISHAGAAVGIRTDFGVVLAAEKKILSKLLETSEASEKMFKLDANIAVAVAGINSDANILINSSRLFAQRYALNYSEQVPVEHLVQSMCDQKQGYTQFGGLRPFGVSFLFGGWDRNFGFQLYQSDPSGNYSGWKATAVGANSQAAHSILKTEYVEGISLSTAKQLSLKVLKQTMDSTILIPDKVELSELAWQDGVPGQVSYRLVRGVELRDLCIAVNRENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML05</accession>
    <name>C1ML05_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_64732</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056089.1">
        <property type="nucleotide sequence ID" value="XM_003056043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML05"/>
    <dbReference type="GeneID" id="9681384"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64732"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="332" mass="36624" checksum="443E60108B3502A4" modified="2009-05-26" version="1">MGSCVVDKPKKQRNKNKNSTAGLCVSEDTAATKIQAAFRGSQSRKRLKAVRKKAIFRNFEELIAASKAWQINCSLPEKASYPVRPDGSAFVTSCHRFVRSHATAVHLPAFVRGFRALLEAQVGQPQVMAWRVRPTILTRSVKGEGALHRWATDAVDLMAMCSLWRKASFAPSKTIDKEKVCDSTEVARKLGATVSSPIRFRWSSTGEKTALGHAGWVETVMRPVPTFSDLGAEIPSSNDCMLDNWLVWSMDPRVNDNDISAALIELEGISSFSSEGRDPLKELSGETFAAHYPGQPFREVSSGTAPEFNSRVLGEDCDWTHAKVRNCCADLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML52</accession>
    <name>C1ML52_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_49469</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056115.1">
        <property type="nucleotide sequence ID" value="XM_003056069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML52"/>
    <dbReference type="STRING" id="564608.C1ML52"/>
    <dbReference type="GeneID" id="9681560"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49469"/>
    <dbReference type="eggNOG" id="KOG0730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ECPKGVL"/>
    <dbReference type="OrthoDB" id="5421at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001025">
        <property type="entry name" value="ATPase family, AAA domain-containing 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF117">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="260"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="559"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="805" mass="86558" checksum="D6B6D832AC39516E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLU0</accession>
    <name>C1MLU0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein arginine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_45363</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057279.1">
        <property type="nucleotide sequence ID" value="XM_003057233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLU0"/>
    <dbReference type="STRING" id="564608.C1MLU0"/>
    <dbReference type="GeneID" id="9682261"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45363"/>
    <dbReference type="eggNOG" id="KOG0822">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IKYAWYE"/>
    <dbReference type="OrthoDB" id="1368803at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000029">
        <property type="entry name" value="Protein arginine N-methyltransferase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007857">
        <property type="entry name" value="Arg_MeTrfase_PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035075">
        <property type="entry name" value="PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035248">
        <property type="entry name" value="PRMT5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035247">
        <property type="entry name" value="PRMT5_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738:SF0">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05185">
        <property type="entry name" value="PRMT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17286">
        <property type="entry name" value="PRMT5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17285">
        <property type="entry name" value="PRMT5_TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015894">
        <property type="entry name" value="Skb1_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRMT5 TIM barrel" evidence="11">
        <location>
            <begin position="36"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 arginine-N-methyltransferase" evidence="10">
        <location>
            <begin position="296"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 oligomerisation" evidence="12">
        <location>
            <begin position="469"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="333"/>
            <end position="334"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="421"/>
            <end position="422"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="Critical for specifying symmetric addition of methyl groups" evidence="7">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH58924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="646" mass="71615" checksum="A31E4347DF28AB5A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMC8</accession>
    <name>C1MMC8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_62445</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056909.1">
        <property type="nucleotide sequence ID" value="XM_003056863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMC8"/>
    <dbReference type="STRING" id="564608.C1MMC8"/>
    <dbReference type="GeneID" id="9682819"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62445"/>
    <dbReference type="eggNOG" id="ENOG502SBWV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AHCWPDP"/>
    <dbReference type="OrthoDB" id="498516at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF46">
        <property type="entry name" value="OS08G0411200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="2">
        <location>
            <begin position="197"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="378" mass="39749" checksum="40E400276134B67A" modified="2009-05-26" version="1">MSVFGTGLDAIARTVAPRPRARCRGRGVRSSSAPGARSGSRRIANESKASSAISTTKIVAVRSRRRVVVSASEDDAATSSSGGNGTSLFPLLPALEPWAAARVQKWASGWEKAAALTPKLPIPVLDLAREDAGEEKGLLRKLAFQTTFGAWVYDKGYRQMFRALGYPGPEGEAAMALRALNQTDAGRPIGGEAAACLDISCGPGIITAKIAEGLTGYDTLIASDYSDAMTRKAAEALDAIIAEDSRTRTGRLQFAAAKADVGDLPFAANSVAGAHASAAAHCWPDPKLGFREVARVLAPGGVFVTSTVVLAGPIKTKFVERGLCADAASYDAKEWKPNTPFWDTPAVVKMLEDAGLVDVEVLAQDKCFVMVKGTKPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMW0</accession>
    <name>C1MMW0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_15400</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056997.1">
        <property type="nucleotide sequence ID" value="XM_003056951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMW0"/>
    <dbReference type="STRING" id="564608.C1MMW0"/>
    <dbReference type="GeneID" id="9682913"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15400"/>
    <dbReference type="eggNOG" id="KOG1027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NCAHEPE"/>
    <dbReference type="OrthoDB" id="63989at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990604">
        <property type="term" value="C:IRE1-TRAF2-ASK1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036498">
        <property type="term" value="P:IRE1-mediated unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10422">
        <property type="entry name" value="RNase_Ire1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.180">
        <property type="entry name" value="KEN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010513">
        <property type="entry name" value="KEN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038357">
        <property type="entry name" value="KEN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06479">
        <property type="entry name" value="Ribonuc_2-5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51392">
        <property type="entry name" value="KEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="KEN" evidence="11">
        <location>
            <begin position="231"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="450"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="450"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="364"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="368"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="481" mass="51847" checksum="EDECA0ACB61E799C" modified="2009-05-26" version="1" fragment="single">EGALDGRPVAVKRLLLQFYELARKELATLIASDEHPNVVRCYALEEDADFVYVALERCASTLAALGPTRAGLRIMRDACAGLHALHARGIVHRDLKPQNVLVTAAFRGKLADMGLAKRLNLTEGTTGDDRGGGGGGTSGWIAPERLLHGRQARSVDAFSLGCLLHFCLTGGGHPFGERYERDARVLRGDHDLRALDHLPEARDLVSSLIRADPAARPTTSEVLLHPMWWSRETRLGFLNDVSDRVEMEDREKGGHLLLAELDRGSWRGALGGKEWTSRLPAGLLDNLGKYRSYDGRALRDLLRVIRNKSNHYRELPKKIQDEVGSYPDGMYDYFARKFPGLLLHAYRFAKDNCAHEPEFRKFFFPSDDGGGGGGDTPDGGGGGGGGRIDGGSGVGGGGIGGGGGIGGGGDGATSASLERAARKAASRSQKRAAERAAVIDATPPVTYPSRPGQPECVFYVKTGRCKFGHTCKFHHPPGIHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMW5</accession>
    <name>C1MMW5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ca2+:Cation antiporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_56683</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/calcium exchanger (CCX) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057477.1">
        <property type="nucleotide sequence ID" value="XM_003057431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMW5"/>
    <dbReference type="GeneID" id="9682916"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56683"/>
    <dbReference type="eggNOG" id="KOG2399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051359">
        <property type="entry name" value="CaCA_antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266:SF33">
        <property type="entry name" value="CATION_CALCIUM EXCHANGER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266">
        <property type="entry name" value="NA+/CA2+ K+ INDEPENDENT EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="177"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="44"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH59122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="316" mass="33300" checksum="5A60905B855D8908" modified="2009-05-26" version="1">MAGRHDPREAWDRRLAARRAHRGRRFVVKLVVVAVVAAVAAAVDGASSTRDPDANVVVGAPEATTTSSSSSSRDPGAARVLLNERAHLATAAVHRSRRGRRRREDASAPWLRPADAAEEEEDVDHCGSVAIDAARDKCAHVARHCGTDATDGLVDYRRLHYCVMRPHPTLSAVLLLAVVVAAFYLLGETSEERFCPVVRRLADALELSPSAAGVTLLALGNGAPDVFACLAAFSASGGGGGGSRGGTLSAVPGGDVGGGMIGATLRRVVSHPGPHTTPCARCTPFLEDFTSRRRFSPPRVTRFQSRLLASTAFNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMY4</accession>
    <name>C1MMY4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH:ubiquinone reductase (non-electrogenic)</fullName>
            <ecNumber evidence="3">1.6.5.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_32597</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a ubiquinone + NADH + H(+) = a ubiquinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:23152"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.9" evidence="3"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057488.1">
        <property type="nucleotide sequence ID" value="XM_003057442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMY4"/>
    <dbReference type="STRING" id="564608.C1MMY4"/>
    <dbReference type="GeneID" id="9682446"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32597"/>
    <dbReference type="eggNOG" id="KOG2495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CTGIKLN"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) (non-electrogenic) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF47">
        <property type="entry name" value="EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="13">
        <location>
            <begin position="64"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="14">
        <location>
            <begin position="531"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="17"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH59133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="597" mass="64636" checksum="54FB3CBB43AD6CB3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN75</accession>
    <name>C1MN75_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_56810</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057532.1">
        <property type="nucleotide sequence ID" value="XM_003057486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN75"/>
    <dbReference type="STRING" id="564608.C1MN75"/>
    <dbReference type="GeneID" id="9682971"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56810"/>
    <dbReference type="OMA" id="VSICHCV"/>
    <dbReference type="OrthoDB" id="498284at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="67"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="182"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="250" mass="25256" checksum="62A11E9C61110F77" modified="2009-05-26" version="1">MSSALAASRLVPPFARRLLVLPNARPPRVVAASSASSSSSRAGVVAMISASSRATSADASPTETETRSGSCFCGAIVVALTGTPAAVSICHCVNCRKLSGAPFTAQALAKATAVEVRSARDAEMDQMVFSPGGDADAYLTAFSSSAAVDRYRCKECGSPVYASLAKGKMAAVPLSMLDGGGGDGGGGGGDGGGGGGEAAAAAKSNAESLRPTHHMYYADRIVDVPDDLPKYVKSAARDAKMWTGVEDDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNB6</accession>
    <name>C1MNB6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_26066</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057551.1">
        <property type="nucleotide sequence ID" value="XM_003057505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNB6"/>
    <dbReference type="STRING" id="564608.C1MNB6"/>
    <dbReference type="GeneID" id="9682515"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26066"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DPNYRNV"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044178">
        <property type="entry name" value="CYP28-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47875">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP28, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47875:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP28, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="146"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="356" mass="36492" checksum="AFD73E5DAEA59A2B" modified="2009-05-26" version="1">MPATATASTASIASRASGGVGGRRAHRRRTRGARVGTDVVVATRARCRLRRDARDDDDDDDDASSSSSSSSPSAIRRRELALGATAGVLLPPASASAATGAPPAIATTEPDVTHVVFLDVALCDANLRADRAMGGGGGALCENAAPLGRVEIGLYGDAVPTTVANFLALIPPRCPPGDGYVRTVFHRVKKGEYVLAGAPGSNRLGQTQIPTTSANDEGRTAGEGAFQRSNPDALNGRALSRRHFRPGTVSLALGAAVGGGDGGFERASPTEFLITTGPGPAPSLDGENVVFGRVLRGLDVVAAIADVPTFKPSGNSIAWNQVAEWFGDDRAAKARAVWTKPTKAIVIENAGVLSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNH3</accession>
    <name>C1MNH3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_55900</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056651.1">
        <property type="nucleotide sequence ID" value="XM_003056605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNH3"/>
    <dbReference type="STRING" id="564608.C1MNH3"/>
    <dbReference type="GeneID" id="9682544"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55900"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GKMEMAR"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="180"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="216" mass="22707" checksum="6FD826A20A22AE28" modified="2009-05-26" version="1">MSSFACRAIAARLVTAATRRRGAGVSLGRRTSPPVAISTSRGLATTSRTAAAADGDAATKSEGARSEDAQQTLAEVTKKLMDCRKRKAAANAVDLLVGLGHAGIQPDLLASTACLGACVAAGKMDLALKVFEEVFDKGVVKPDEVVFTELIRGHLRADPPAWARITGLLNRMPEHGVNPTALTYNLLLARCADDNELERAEALVDRMADDGIEPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNK0</accession>
    <name>C1MNK0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">plant cystathionine gamma-synthase</fullName>
            <ecNumber evidence="7">2.5.1.160</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_25455</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-homoserine + L-cysteine = L,L-cystathionine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:80891"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="EC" id="2.5.1.160"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-succinyl-L-homoserine + L-cysteine = L,L-cystathionine + succinate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20397"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57661"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-cystathionine from O-succinyl-L-homoserine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.160" evidence="7"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057119.1">
        <property type="nucleotide sequence ID" value="XM_003057073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNK0"/>
    <dbReference type="STRING" id="564608.C1MNK0"/>
    <dbReference type="GeneID" id="9682108"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25455"/>
    <dbReference type="eggNOG" id="KOG0053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NAFQIIQ"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000046">
        <property type="entry name" value="Cystathionine gamma-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000033">
        <property type="entry name" value="Cystathionine gamma-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044639">
        <property type="entry name" value="CGS1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43379">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43379:SF1">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00060510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00093222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00093261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="374" mass="41368" checksum="A8AB5BF51D17F8D1" modified="2009-05-26" version="1">MSDTLATPVCLNSTYWFKDTEELIAYQENKYQSYEYGRYGNPTTKTCEEKIRMLEGGEDCLLSSSGMNAAICMLLALVPANGHIVTTTDCYRRTRQFVQTFMPKMGITCTVLDPSDYDGLEKALNENDCSLYFSESPTNPYLRCVDVERISKLCKPKNCIVCVDGTFATPVNSKALSRGADLVIHSASKYLGGHNDVLAGCIVGDKELVAKCRQFHNIMGGVLDPHAAYLVLRGMKTLSLRVARHNDNAMRLATLLEAHPKIDVVHYPGLPSHPDHEVAKRYMSGFGGVVSFEVKGDLWATAKFIDACNLPYIAPSLGGVESLIEQPTIVSYWDYGAEQRAELGIKDNLVRYACGIEDFEDIASDVLQALEQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP56</accession>
    <name>C1MP56_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA (guanine(37)-N1)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA methyltransferase 5 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_46659</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion matrix</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Predominantly in the mitochondria and in the nucleus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRM5 / TYW2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="10"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057226.1">
        <property type="nucleotide sequence ID" value="XM_003057180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP56"/>
    <dbReference type="STRING" id="564608.C1MP56"/>
    <dbReference type="GeneID" id="9682202"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46659"/>
    <dbReference type="eggNOG" id="KOG2078">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="408788at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070901">
        <property type="term" value="P:mitochondrial tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.110:FF:000001">
        <property type="entry name" value="tRNA (guanine(37)-N1)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03152">
        <property type="entry name" value="TRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025792">
        <property type="entry name" value="tRNA_Gua_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF43">
        <property type="entry name" value="TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 10 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="12">
        <location>
            <begin position="238"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="25"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="372"/>
            <end position="373"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="402"/>
            <end position="403"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH58871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="532" mass="56691" checksum="C9AB151E2F7D5AC5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPA9</accession>
    <name>C1MPA9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56209</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056788.1">
        <property type="nucleotide sequence ID" value="XM_003056742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPA9"/>
    <dbReference type="GeneID" id="9682227"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56209"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="138" mass="14526" checksum="2767EC1C137055CD" modified="2009-05-26" version="1">MCDSAYALSRSPREASHCTARRMTANVPCLTSGGPSRARRQAAGAAVSIVDSADDAFSARRIASTTRASSAGRSFAALAISMECAVAISHDRGRSERGWSSRRAEVCVGFQTEARLPDSGLGRTKTGTEATSRRRAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPF5</accession>
    <name>C1MPF5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_32727</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057950.1">
        <property type="nucleotide sequence ID" value="XM_003057904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPF5"/>
    <dbReference type="STRING" id="564608.C1MPF5"/>
    <dbReference type="GeneID" id="9683055"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32727"/>
    <dbReference type="eggNOG" id="KOG2576">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YHSTDFD"/>
    <dbReference type="OrthoDB" id="1689333at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042283">
        <property type="term" value="F:dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF2">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH57901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="500" mass="53467" checksum="1A7AB18934097677" modified="2009-05-26" version="1">MGPALEPEASEASPAASGARVAAPYVRAFLFITSLKLLLVPCYKSTDFEVHRNWLAVCSRPVSRWYVDATSEWTLDYPPLFGWFARLVSIAARRVDPGMLTLSSAPYDSPATTTFMRCSVIASDALLAAGAFAWTNGRGRQRQRAIATILVLLNPGLLLVDHVHFQYNGALFGLLSCALAAVRARRPVLAAALFSALVHAKHFAAVAIAVTAASFGPVVASGTFSAMLARLFPFGRGLSHAYWAPNAWALYNFTDKCLAAAARKLGVGATDAPKAHLVGGMAGHGGTGAQTHAVLPTITPGMTFALTALFSAPALAAHWRAALRVLSHATLCAFTFGWHVHEKASLMATIPLALALAADADSAGRAGEFWLLSTTSSYALSPLLFQPREWPIKILVLLIGAIVSRRVLETVVEDKARAEGVADADGGGEEWTLLRSTSHRAYVVYGLPALELYVSVGHRLVFGEDALEFLPLMLTSTYCAVGVVGVFAKQWIAYVREVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQB4</accession>
    <name>C1MQB4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57226</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057727.1">
        <property type="nucleotide sequence ID" value="XM_003057681.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9683537"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57226"/>
    <dbReference type="OMA" id="ANDIETH"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="549"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1309"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1444"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1530"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1584"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1739"/>
            <end position="1760"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="352"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="621"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="704"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="764"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="901"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1449"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1459"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1625"/>
            <end position="1644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1775" mass="183119" checksum="9A59CA4E295779E8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQF9</accession>
    <name>C1MQF9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57277</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057750.1">
        <property type="nucleotide sequence ID" value="XM_003057704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQF9"/>
    <dbReference type="GeneID" id="9683559"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57277"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="69" mass="7935" checksum="4389A593E007D555" modified="2009-05-26" version="1">MPNQRTHRRRRRRKNGADPTPPRGPLDDITEDLACLVFTHVDYLRDRRSLSAVSKVVGRDRKRLGPSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQJ7</accession>
    <name>C1MQJ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57316</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058137.1">
        <property type="nucleotide sequence ID" value="XM_003058091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQJ7"/>
    <dbReference type="GeneID" id="9683210"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57316"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="377"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="565"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="725"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="261"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="578"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="751"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="778" mass="81288" checksum="86ABA166EE311689" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQJ9</accession>
    <name>C1MQJ9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin--tyrosine ligase-like protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_3463</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tubulin--tyrosine ligase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057772.1">
        <property type="nucleotide sequence ID" value="XM_003057726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQJ9"/>
    <dbReference type="STRING" id="564608.C1MQJ9"/>
    <dbReference type="GeneID" id="9683577"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3463"/>
    <dbReference type="eggNOG" id="KOG2157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NDITMHL"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF39">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="370" mass="42481" checksum="F8182657649A5A20" modified="2009-05-26" version="1" fragment="single">GRVVRFGTTARHTIPYKVLKARGWKEVDDDSWDFFYADVGWIHENITYTTSNKGLTLEPHQRVNHFPNHVELTRKDLMAKNVKRAIKLAVKEGRDPSEFDFIPVTYTLPSEGNMLLREFKERGGTWIMKPIGRAQGKGIWIASKPSQIEQWMKERGMGKAENNVCYENFVAQRYLEDPYLVGGKKFDMRIYAVCLSYNPLRVYLYREGFARFTATRYSKEDFDNPMVHLTNHAIQKKDDAYDASVSDLKWSFPSLKRYMLTKHGPAATTECWAGIHNIITGSLKAVQGVMINDKHCFEMYGYDVMIDDDLKPWLIEVNASPSMSSDTQTDHDLKFGLLDDMLTLIDMTGSFRGQLPPRVGGFDLVYDGEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRZ8</accession>
    <name>C1MRZ8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CCT-beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_45559</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058964.1">
        <property type="nucleotide sequence ID" value="XM_003058918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRZ8"/>
    <dbReference type="STRING" id="564608.C1MRZ8"/>
    <dbReference type="GeneID" id="9684403"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45559"/>
    <dbReference type="eggNOG" id="KOG0363">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAEMVMS"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03336">
        <property type="entry name" value="TCP1_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000025">
        <property type="entry name" value="Chaperonin containing TCP1 subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000002">
        <property type="entry name" value="T-complex protein 1 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012716">
        <property type="entry name" value="Chap_CCT_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02341">
        <property type="entry name" value="chap_CCT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH57419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="533" mass="57089" checksum="8188E700E4DD6133" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS52</accession>
    <name>C1MS52_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 77 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47386</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058626.1">
        <property type="nucleotide sequence ID" value="XM_003058580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS52"/>
    <dbReference type="GeneID" id="9684425"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47386"/>
    <dbReference type="OrthoDB" id="540503at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052636">
        <property type="term" value="F:arabinosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052325">
        <property type="term" value="P:cell wall pectin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053250">
        <property type="entry name" value="Glycosyltransferase_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46936">
        <property type="entry name" value="ARABINOSYLTRANSFERASE XEG113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46936:SF1">
        <property type="entry name" value="ARABINOSYLTRANSFERASE XEG113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="2">
        <location>
            <begin position="171"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="924" mass="98278" checksum="1498112D26BBC950" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSR5</accession>
    <name>C1MSR5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_7243</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058723.1">
        <property type="nucleotide sequence ID" value="XM_003058677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSR5"/>
    <dbReference type="GeneID" id="9683812"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7243"/>
    <dbReference type="eggNOG" id="KOG1207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RMYTTSS"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF2">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY SUPERFAMILY (AFU_ORTHOLOGUE AFUA_3G13450)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="189" mass="19847" checksum="DF53EC061D9325E3" modified="2009-05-26" version="1" fragment="single">ARVLVTGGNRGIGLALVKELVACGANVIVTCRKSNDEIDGMAPAVQVIEGVDVTDTESVKAMTRALDAPVDVLINNAGYFYEPVETIENMAFDEELKMIDICAVGPLRVASALYNAGLIAKPGGKIAMITSQGGSVSWRVVQNPTGHDFGHHMSKSAANMGGVLLAQELGPRGILVQMLHPGFNKTGMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTN8</accession>
    <name>C1MTN8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58140</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058893.1">
        <property type="nucleotide sequence ID" value="XM_003058847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTN8"/>
    <dbReference type="GeneID" id="9684332"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58140"/>
    <dbReference type="OMA" id="REAHTMG"/>
    <dbReference type="OrthoDB" id="5514856at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="72" mass="7980" checksum="74A672D3FCB77AB2" modified="2009-05-26" version="1">MKAIRLERVADRAGHNDAREAHTMGVIDTIKSEIAHQFSDANRESTVTFLRSAGLFVTAIVFMRNFGDAMAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU24</accession>
    <name>C1MU24_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58642</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059422.1">
        <property type="nucleotide sequence ID" value="XM_003059376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU24"/>
    <dbReference type="GeneID" id="9684576"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58642"/>
    <dbReference type="OrthoDB" id="10685859at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="429" mass="44606" checksum="271ED4FF29BD9B87" modified="2009-05-26" version="1">MRPDLGPPPKPPVPLARTEKLAAGLLELLAALLSHDAIRDDACRVGGDVEAARGLLPSGKHRPTWTTTIVHQARSIHWSPYDPVGVFLPAATYERPATPTPPEEEAGAAAEGGAEGGEEGGGEGGEDAAAAAAAEGGEEEKPGPAADGEAKRDDDGGGAADAEVYDADANDDKKSFDTWDWEPVVVPGDPPWDDHLVCEAALRALEICARHPRCRAQLNEDDGAGVKQLCEVLKREMRGCVEPTLRIMLLLMAHARQKREEGGGGCGGEEEEEEEAASSVGEGEEAEDGAKPEPKAKPFDVLADADVKATLNGVGTGDPGSAAYDQLRLTKALSLVAYPLEEVLPDRRPRPPTPDPPPPPPKVPLLVGHMKGTLRVAVGAHKQLEEAAIRAKEGAGEEVGPEGGGEGGGGEGEGDAAPGEDVLEIVTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUF7</accession>
    <name>C1MUF7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ferredoxin, chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PETF2</name>
        <name evidence="11" type="ORF">MICPUCDRAFT_58790</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 2Fe2S plant-type ferredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059188.1">
        <property type="nucleotide sequence ID" value="XM_003059142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUF7"/>
    <dbReference type="STRING" id="564608.C1MUF7"/>
    <dbReference type="GeneID" id="9684928"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58790"/>
    <dbReference type="eggNOG" id="ENOG502RXRY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WELPNAC"/>
    <dbReference type="OrthoDB" id="1885901at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43112">
        <property type="entry name" value="FERREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43112:SF10">
        <property type="entry name" value="FERREDOXIN C 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="10">
        <location>
            <begin position="251"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="381" mass="39844" checksum="97B466ACFD10E260" modified="2009-05-26" version="1">MHRTITSASCSSAASTAGRACAAARGVATRARARASSFTSRIFSHGARVSKNATTISTRPRAASDDGEASGGAEVSLMSKAEGLLEKVGLSLGPIGMTLGESKAKLEASVDDDFDDDDVENDENDVVAKGGEMLDNAGLSLGPIGMTLGGAKAKAKAKAAGVGPDASAGTGASAKPKSIAPLTTAEWRAKNVNPDGTVDLFVEDHYNVASRVAGGVEGLSQGGGSSDNNLVNVENIAWSGLPSDAVDGARHRVAVTDHVTGEVLELDVPENRYVLFEAEQEGWELPNACRMGCCTKCAVRVTKGKLEQREALGLSRRYRDEGYALLCVSTVVAGPVECVTQDEEEIYQKQFGEVFNELAADKRSKAVVRDDFALEIADMDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUI4</accession>
    <name>C1MUI4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_40214</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059204.1">
        <property type="nucleotide sequence ID" value="XM_003059158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUI4"/>
    <dbReference type="STRING" id="564608.C1MUI4"/>
    <dbReference type="GeneID" id="9684939"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40214"/>
    <dbReference type="OMA" id="GSPRYLM"/>
    <dbReference type="OrthoDB" id="525524at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090090">
        <property type="term" value="P:negative regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029775">
        <property type="entry name" value="NPHP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058765">
        <property type="entry name" value="NPHP4_C2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31043">
        <property type="entry name" value="NEPHROCYSTIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31043:SF3">
        <property type="entry name" value="NEPHROCYSTIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26186">
        <property type="entry name" value="NPHP4_C2_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NPHP4 C2-like" evidence="2">
        <location>
            <begin position="931"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="747"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="833"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="763"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1092" mass="112949" checksum="35466E73347A0BED" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUI6</accession>
    <name>C1MUI6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40216</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059205.1">
        <property type="nucleotide sequence ID" value="XM_003059159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUI6"/>
    <dbReference type="GeneID" id="9684940"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40216"/>
    <dbReference type="OMA" id="WMEDAMT"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="315" mass="32779" checksum="5D7CE20A0FF260D6" modified="2009-05-26" version="1">MAVDEDAEAAWEDDHRRRSSSGDRGLPSRLAHLRGPSSTTPAASRAPPPARPTVQPTVRTASGKTLMGPWVGRFARADADLADAGGASSQLCDSDEEDFFIARSSSPIDVMDADPPTPESCARYTPRGAKRHSAAAFSFDAVDVDALTDVAFAGPDETPTDHAAVTRELMLEDAITGRAAGGAGADARARILPWSSPPGTGVKRDHAEPAPAFDTRRFARGSGGRGRREARSAPAATRRVGGARVSARTKARAPHAVARATKEKLASTRLEATGGEASRGLFGGGKNTAFGSRNNGARNTMGTRCLQPRGGGGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUV3</accession>
    <name>C1MUV3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58945</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059258.1">
        <property type="nucleotide sequence ID" value="XM_003059212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUV3"/>
    <dbReference type="GeneID" id="9685004"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58945"/>
    <dbReference type="OMA" id="RASCHAT"/>
    <dbReference type="OrthoDB" id="10616017at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="346" mass="38914" checksum="00F7F52ACAE14E81" modified="2009-05-26" version="1">MSGSCTRLRGLRALISSCGNWRASCHATGSTSTRTRCLASSSGAGEREEGTTVGEKVEALIRRVDERWRFVEDPEDMRGVMQALRHCHVMQRVGPKNLMLRFVLAEDDVGESWVVPDASTAYPVRERMASSRARIIEKELTRDAQKLFYKACLSATSAKTIDIPATNDDIDATFAEQDFTSMLDAAVEASLEKHTKRVREIDTNDNSTTSWILKPRDADRAREHDDLNDTRDIWCGTSSDIEPYARILHILSDGEILAALRKNEGNDNITSENYENVKNTLLRDIGHANVDGNSQRNACVVLQNVSNKVSYRLHHAQLRLHLFRQSILEGGPLIDFKLKKKKKRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV35</accession>
    <name>C1MV35_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_69744</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059302.1">
        <property type="nucleotide sequence ID" value="XM_003059256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV35"/>
    <dbReference type="GeneID" id="9684742"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69744"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="490" mass="51990" checksum="C93D02680AB3C67B" modified="2009-05-26" version="1">MFAGKDKRFELIRELQVAEEDEATHRAKKITEEERAAIADANDRTGRAGAGMLGLLTEKNHGVTQLILMQTDLATRRREERALNYAAARIQAVCRGRATRKAEARRRAEEEASGGLPDIASFEPEEIAHVTRIQSSFRGRSSRRNMRLYGTPSKPKDLSKDLKEPSTPPIPPPPPANKEPAAEPATPPRAPAPKEPEEEDLDPLANLSAEDLEKVMAMQSSAKKIVDKKSLESELGEPLATLPADALGSSPSALVSAATLQRAATARLDDVPAQPRVRGARGLASAILLQSAAATRAREVDADAAFEAKMDAALEEPLEAEKAKEKMPENDASASIESIEDSAAFRLADVSDASLAAIVGVQAAAAGFLSRAKAAAREKRLAASGVSQRASTRADVTYAVSSRVLDESVDEDATETIRVQNTQRHARRRGSRRAVDGGAFGGLSETREEGEEGGDEGDAELEGAAAGATSSREALESKIAEARGKGGGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVM4</accession>
    <name>C1MVM4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_65417</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060063.1">
        <property type="nucleotide sequence ID" value="XM_003060017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVM4"/>
    <dbReference type="GeneID" id="9685501"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65417"/>
    <dbReference type="eggNOG" id="ENOG502S2NC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MVGANFI"/>
    <dbReference type="OrthoDB" id="497914at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="368" mass="39483" checksum="5D800244EB9CB540" modified="2009-05-26" version="1">MATPAVKRKRRVLKPLKKEPAVDETASWETVSVDEGNCPSDGCSFEAALPFDENKYARGYQASKHSSEDARARLAIQVETLRAQREADLQAKAAVLAEIERAREAGMSAEEKAAAKAQKDAFYFSVAGLASLAALQPCAPADAAITTAAGIDPFFNFNPVCPASDGVFRVGQKAALSLAGDQNIENYRPLINDVLIRVRTELCILESFSRETMVPFIKEKGVGWVLPLHETSETYLAGVVFMVGANFILLGSTKVVAILAIYHDLARGFSRAPRAAARDGDPGGGRGETRARVQRADGPADDGDQGADGRDERAGEGGAAAGVREGVRGAARGLEVFDTFCSRYFVAFTVTYVLVKTGHYVLFPNLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW04</accession>
    <name>C1MW04_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_34311</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059842.1">
        <property type="nucleotide sequence ID" value="XM_003059796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW04"/>
    <dbReference type="GeneID" id="9685567"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34311"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PNVMSIC"/>
    <dbReference type="OrthoDB" id="10261634at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="12"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="304"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH55794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="329" mass="35308" checksum="0181AC9FD16047C3" modified="2009-05-26" version="1">MAAANTAHSVGMIAAWYFSNIGVILLNKYLLSVYGFRFPVFLTTCHMAMCALLSLIVRASGIAPRQSVKNRAHLRKIGVLGVIFVASVVAGNVSLQHIPVSFNQAIGATTPFFTAVLSLCIMRQKETMQVYATLVPIVLGIVVASRAEPLFHLFGFLACVTATFCRALKSVIQGMLLSNESERMDSINLLLYMSPIALSVLSVASTVMEPEAFGVFYDNCAESPRFFFIITLNCVLAFSVNLTNFLVTKCTSPLTLQVLGNAKGAVAVVVSILLFKNPVSVVGMFGYAVTIVGVAWYSSAKKKAPGDRRGKREGVGNSALGGGRMSEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW54</accession>
    <name>C1MW54_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59631</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059864.1">
        <property type="nucleotide sequence ID" value="XM_003059818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW54"/>
    <dbReference type="GeneID" id="9685303"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59631"/>
    <dbReference type="eggNOG" id="KOG2377">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VAMCARL"/>
    <dbReference type="OrthoDB" id="26384at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035658">
        <property type="term" value="C:Mon1-Ccz1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040371">
        <property type="entry name" value="RMC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12897">
        <property type="entry name" value="COLON CANCER-ASSOCIATED PROTEIN MIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12897:SF4">
        <property type="entry name" value="REGULATOR OF MON1-CCZ1 COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="667" mass="70299" checksum="7E9F977DAC598D35" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWK7</accession>
    <name>C1MWK7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47799</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059938.1">
        <property type="nucleotide sequence ID" value="XM_003059892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWK7"/>
    <dbReference type="GeneID" id="9685377"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47799"/>
    <dbReference type="eggNOG" id="ENOG502QVZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="567980at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013989">
        <property type="entry name" value="Dev_and_cell_death_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044832">
        <property type="entry name" value="NRP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46034">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46034:SF7">
        <property type="entry name" value="INFLUENZA VIRUS NS1A-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10539">
        <property type="entry name" value="Dev_Cell_Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00767">
        <property type="entry name" value="DCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51222">
        <property type="entry name" value="DCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DCD" evidence="2">
        <location>
            <begin position="30"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="300" mass="30615" checksum="D2F8C859EAE87ED8" modified="2009-05-26" version="1" fragment="single">MALRTASELLDALDAGAMPAGDRDDGGDDGELGGVIFICSRETYDDTTRAGLFGLTQGSWSFVKRITPGMPLFLYNLTERRFHGVFEATSDGAMNADPTAWKTSGAGAGDAAGIDGSPYPAQVRYKHTRVTCSASAASCKPFLRFAAGEANGKKFRLDLTPGEATRLARVFHAGGDAGGGAKKGLNGKSGGGHHQTNGRAATPTHDVVDGWETVSSKKTTKKGGGGGSGGGSSPTTRRNNNNNGAAADGKDKIARGGKAAAGESYHHHHIHASSSALGDAADRASPPPPPPPPGPPRAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWZ4</accession>
    <name>C1MWZ4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <shortName evidence="4">HIB-CoA hydrolase</shortName>
            <shortName evidence="4">HIBYL-CoA-H</shortName>
            <ecNumber evidence="2 4">3.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">3-hydroxyisobutyryl-coenzyme A hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_18430</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="2 4"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059718.1">
        <property type="nucleotide sequence ID" value="XM_003059672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWZ4"/>
    <dbReference type="STRING" id="564608.C1MWZ4"/>
    <dbReference type="GeneID" id="9685096"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18430"/>
    <dbReference type="eggNOG" id="KOG1684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ECFRTFY"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004127">
        <property type="entry name" value="PRK05617.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="5">
        <location>
            <begin position="19"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU369070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="436" mass="47139" checksum="3D80DC3BB81FAF95" modified="2009-05-26" version="1" fragment="single">LAKMSSDADDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERPCLCAGGDVKAVYDMRPPEVDPKRHKAPPLALEFFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSNLPGRVGHALALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATALERTFSGGETTSELDRNAKDWANKVDEELRKLEKETSGEVKETPNDLHPHLAVIDRWFVSDDVQEVDLTLNAAAVGGRRERERKVAKELLELMRAGCPASLRVTAAMLKRVRPPVDIMNVSGGPPPPLDLARCLRMEFRAVAECISRDDFYEGVRARLVDKGKGDPPAWSPESVEEVGHEDVETFFEPGSREVEEVIARFERAVGLESDAGGAGAGAGSSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX70</accession>
    <name>C1MX70_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_60050</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060344.1">
        <property type="nucleotide sequence ID" value="XM_003060298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX70"/>
    <dbReference type="STRING" id="564608.C1MX70"/>
    <dbReference type="GeneID" id="9686079"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60050"/>
    <dbReference type="eggNOG" id="KOG0066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ARLVLCM"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000549">
        <property type="entry name" value="ABC transporter ATP-binding protein arb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF14">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="169"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="567"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="495"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="505"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="797" mass="88701" checksum="2137B16455A69E85" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXH1</accession>
    <name>C1MXH1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_60157</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in the control of DNA replication and the maintenance of replication fork stability.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CSM3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060394.1">
        <property type="nucleotide sequence ID" value="XM_003060348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXH1"/>
    <dbReference type="STRING" id="564608.C1MXH1"/>
    <dbReference type="GeneID" id="9686130"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60157"/>
    <dbReference type="eggNOG" id="KOG3004">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ENELWND"/>
    <dbReference type="OrthoDB" id="437078at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031298">
        <property type="term" value="C:replication fork protection complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012923">
        <property type="entry name" value="Csm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040038">
        <property type="entry name" value="TIPIN/Csm3/Swi3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13220">
        <property type="entry name" value="TIMELESS INTERACTING-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13220:SF11">
        <property type="entry name" value="TIMELESS-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07962">
        <property type="entry name" value="Swi3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="9">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="42"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="196"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="363"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="380"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH55163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="518" mass="55843" checksum="787BA0359AC1FA20" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXH4</accession>
    <name>C1MXH4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_18853</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060694.1">
        <property type="nucleotide sequence ID" value="XM_003060648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXH4"/>
    <dbReference type="STRING" id="564608.C1MXH4"/>
    <dbReference type="GeneID" id="9685834"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18853"/>
    <dbReference type="eggNOG" id="KOG2913">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LIMNASW"/>
    <dbReference type="OrthoDB" id="497757at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000009">
        <property type="entry name" value="PQ loop repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF34">
        <property type="entry name" value="LYSOSOMAL AMINO ACID TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="344" mass="36847" checksum="C4DCB028C86B50A0" modified="2009-05-26" version="1">MSFTCECSRGEGSVDWVRPPPARARRPALLGRSPSRVVRILPPRPSIRPASFQIRATFKDCVYTVPDELGFYLGLVSIACWLFAQLPQMLRNYRLKSAESLSPYFLAEWLAGDAMNLSGCLFAGDQLPSQVYTACYFVCVDVGMIAQYAYYALSRRDALALAAAAACVVVVVGVFFFAGRDGAWSNRWASHRSRDHSRHRSSPPSPSSLPYCDVSTNPEWEVAIGRAAGYVSSAFYLGSRVSQILKNRARKSCEGLSAAMFATAVAANVTYGVAILLRAASWAGVLASAPWLLGSLGTVALDVTVLAQSRRYGGGGGGGGGEEGEALEGEETAALLPSERGSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXP3</accession>
    <name>C1MXP3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_69159</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060433.1">
        <property type="nucleotide sequence ID" value="XM_003060387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXP3"/>
    <dbReference type="STRING" id="564608.C1MXP3"/>
    <dbReference type="GeneID" id="9685871"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69159"/>
    <dbReference type="eggNOG" id="KOG2834">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DYTMSTA"/>
    <dbReference type="OrthoDB" id="10251089at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08061">
        <property type="entry name" value="MPN_NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17055">
        <property type="entry name" value="Ubl_AtNPL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016563">
        <property type="entry name" value="Npl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007717">
        <property type="entry name" value="NPL4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024682">
        <property type="entry name" value="Npl4_Ub-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710:SF0">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05021">
        <property type="entry name" value="NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11543">
        <property type="entry name" value="UN_NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="432" mass="47346" checksum="80F8B0696AF47744" modified="2009-05-26" version="1">MPLLLRIRTRDGTERLTVDANCTLRQLREKIETEYGVPQEDQTLSLNQGLLLANARAEDFDDLAPARAKDAKLVRQLGIDHGSIVYLSYSVEREPTPTAAASHRSELRGGKMTVEAMIAAQTRVERQETPNCASVSFDAHAANAFQQYVNGTLGFNQMRFGWMYGTVNDAGEVLVDAIYEPEQEGSEDAFIISEGSEEDARADALASALGMQKVGCVFNITTTKPRKFTLSAFEVREMAKRQAAAAAAAAAAAAADGAEKKDGKTTFVTAVVMMLEDEDEGPQVSFEPFQVSDQCVRLYADGWFHDEPCEDRGLTRMTKEVIVADGVSKDVTEVDNDRWLVAVPIKDHSGALSTKFPIENRLHPIQTMEDLKDSLSQSGMEYSARLRDFHLLLFLSKHLGTDDLVDVAKTARRGGTIAEGYKIIIDSLAGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY00</accession>
    <name>C1MY00_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60347</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060786.1">
        <property type="nucleotide sequence ID" value="XM_003060740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY00"/>
    <dbReference type="GeneID" id="9686223"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60347"/>
    <dbReference type="eggNOG" id="KOG1611">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WHREGYE"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="246" mass="25750" checksum="96549775B624E8D7" modified="2009-05-26" version="1">MPLNVVVTGANAGLGLELCKQLTARGDVVYASCRAPTAELEAVGVKKIIHDVDVTADDAGDRLARALDGVRVDAVINNAGGLGSNPGRSWDEQFEDQKFATLDFRVMQRAFEVNTLGPIRVTKALTPKLKESKGKVLIVTSLMGSISDNGSGGAMAYRCAKAAVNMAAATMASELREAGVAVGLVHPGMLKTNFGGGTPPANMMKWFKPVEGGGRGVLMALDALTMETTGSFVHGNYGEGLKPCPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY95</accession>
    <name>C1MY95_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_59825</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060536.1">
        <property type="nucleotide sequence ID" value="XM_003060490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY95"/>
    <dbReference type="STRING" id="564608.C1MY95"/>
    <dbReference type="GeneID" id="9685709"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59825"/>
    <dbReference type="OMA" id="YAIEASY"/>
    <dbReference type="OrthoDB" id="194289at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021836">
        <property type="entry name" value="DUF3429"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15887">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15887:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11911">
        <property type="entry name" value="DUF3429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="315"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="390" mass="40806" checksum="BDC335DA2D566EAA" modified="2009-05-26" version="1">MNHPSVVAATRAARDAFARATTGLKLPKDFSIPKVPFSMADLSKLNLRAPAGWEERFARVGLHPEHLKEAPHWSPLALGAAGAIPFLALSAPVANLVGLPDRVEAHRAQIQASYAVAIVSFLGGCHWGFAASAGGIAKAAAAPVSSAAVTAATAEISRVAAALGVSAAEASVLLAGPARFAWATTPALMAWISASAFTLPWQMVTLSGSLLAALAADVTAARHGLMPRWMMPMRHALTAAAVASLLTNVPYAIEASYDEVSSEPTLDSRESELRRYRKETPKQAQELKKREKSLSESAAAVATLRSEKDASAVALQRQRDATREAEARLAATREEAATAKKALAAADDAKDAAARELAAVKEELERAVKAGVEARKELKLAEKAASGSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYY1</accession>
    <name>C1MYY1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Clathrin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_60531</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasmic vesicle membrane</location>
            <topology evidence="2 7">Peripheral membrane protein</topology>
            <orientation evidence="2 7">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <location evidence="7">Coated pit</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="7">Cytoplasmic face of coated pits and vesicles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the clathrin light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061118.1">
        <property type="nucleotide sequence ID" value="XM_003061072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYY1"/>
    <dbReference type="STRING" id="564608.C1MYY1"/>
    <dbReference type="GeneID" id="9686302"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60531"/>
    <dbReference type="eggNOG" id="ENOG502R77G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10633337at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000996">
        <property type="entry name" value="Clathrin_L-chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639:SF7">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01086">
        <property type="entry name" value="Clathrin_lg_ch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0168">Coated pit</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="158"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="267" mass="27479" checksum="E74EE9450C13EE17" modified="2009-05-26" version="1">MAADDFFAAPGAPPPIEPAGADDAVAAAPALEPPAEPVEFTASFDAPPPVPPPASDFEDAAPAIVAADAPAPPPLAMDDATMFSAPSASGSQSDMTGMGGGVPSVDGVASLGGGSLGSHGDAPAGSAIDADAFGGAAYDAPVGSAPTMEQEQFSSNAMAEWRAEQARLIAEKDAAEQRELQVIREEAQAERELMYSQREKQLDAAFKTNRERQESVVQDMELKGWEAVVNLSSDSNLVPGSTADLAKYKALLTRLKHKEPEAFSAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYY7</accession>
    <name>C1MYY7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_7364</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061121.1">
        <property type="nucleotide sequence ID" value="XM_003061075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYY7"/>
    <dbReference type="STRING" id="564608.C1MYY7"/>
    <dbReference type="GeneID" id="9686560"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7364"/>
    <dbReference type="eggNOG" id="KOG1098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LDAWFRF"/>
    <dbReference type="OrthoDB" id="1287559at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000004">
        <property type="entry name" value="AdoMet-dependent rRNA methyltransferase SPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF13">
        <property type="entry name" value="PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005461">
        <property type="entry name" value="23S_rRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="9">
        <location>
            <begin position="12"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="197" mass="21811" checksum="D4045B4D83E63CC3" modified="2009-05-26" version="1" fragment="single">DKFYYLAKEQGFRSRAAFKLVQLNRKYDFFSGARACMDLCAAPGGWLQVAVKYMPMSSTIVGVDLAPIKAIRGCTTFVDDITTQSCRAQLKRVTPDGVKYDVVMHDGAPNVGGNFAAESYTQAALTLDSLRLATEFLREGGWFVTKVFRSTEYHALLYSMQQLFKKVESTKPVASRGTSAEIYVVCIGYLAPSKIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZH0</accession>
    <name>C1MZH0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60728</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061217.1">
        <property type="nucleotide sequence ID" value="XM_003061171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZH0"/>
    <dbReference type="GeneID" id="9686656"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60728"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="203" mass="20531" checksum="8C3A781DE1D2B27B" modified="2009-05-26" version="1">MNSTPTFACIERHSETSVRGAGAARHAPADMMASGRRIDPTPSYRIGGISIRHPGGAGVGSSSSGSSVYAERPSQKLPPPRRAGALPDLANGRPSNHSRLPAINGATTRDRDRDRGGGDASSGTGGFDKSKYAVQAIPSFDGGRRRGVAPGFSFGGGGGDRDPFGATSPMRDATDKMAGLGVQGVGGRAGGRRVGGGGGGTWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZU3</accession>
    <name>C1MZU3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_11647</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061280.1">
        <property type="nucleotide sequence ID" value="XM_003061234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZU3"/>
    <dbReference type="STRING" id="564608.C1MZU3"/>
    <dbReference type="GeneID" id="9686452"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11647"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="32"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="134" mass="14819" checksum="CFA947CBAE37A12A" modified="2009-05-26" version="1" fragment="single">IKNLFDGYDVDRSGSLTQNEIQALLKDLAQDAGPDAIKKALNDMDQNGDNEVSIMEFKRYFLGPWAKMQMAKQFKDVGVDVNGEIDLETLRSALNAMGSAPNDQILNEMFAKVDAGKRGSVPVAKFVSWATYQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>C1N057</accession>
    <name>C1N057_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_35134</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061336.1">
        <property type="nucleotide sequence ID" value="XM_003061290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N057"/>
    <dbReference type="STRING" id="564608.C1N057"/>
    <dbReference type="GeneID" id="9686510"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35134"/>
    <dbReference type="eggNOG" id="KOG0062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1242">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ELHCAML"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18626">
        <property type="entry name" value="CD_eEF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000193">
        <property type="entry name" value="Probable Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015688">
        <property type="entry name" value="eEF3_ABC2_chromodomain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="409"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="656"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="13">
        <location>
            <begin position="793"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH54986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1048" mass="116220" checksum="28648ACDBC158C72" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0G8</accession>
    <name>C1N0G8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_51014</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061638.1">
        <property type="nucleotide sequence ID" value="XM_003061592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0G8"/>
    <dbReference type="STRING" id="564608.C1N0G8"/>
    <dbReference type="GeneID" id="9687077"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51014"/>
    <dbReference type="eggNOG" id="ENOG502S0Q0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HMCGMSQ"/>
    <dbReference type="OrthoDB" id="1577640at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="145"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="179"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="259" mass="27217" checksum="3FA6C82877FE837B" modified="2009-05-26" version="1">MSSSSAKAAHYRADGVRITHDPHAPGMAEVHSIHWSPYDRVRVKYGAPGETDRDGFDPYADSVGAGIYGGVVKRRPEDGSVVIGKQYQGHNPRPGPVYAGGGYTPVSDAIATFNREVSGGVPTPETTLAKLLDAHPDLVNDVSTGGASPLHTCGMSRANQHATAFLISRGADVDAVDAYGFTPLDRAASNNLAIAAEALLKRGADPDANGPPRDVATQSEARDVLKALDARAKEGGRVDSGASRTLVPIRPRWCGELRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0R4</accession>
    <name>C1N0R4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_62908</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061685.1">
        <property type="nucleotide sequence ID" value="XM_003061639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0R4"/>
    <dbReference type="STRING" id="564608.C1N0R4"/>
    <dbReference type="GeneID" id="9686876"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62908"/>
    <dbReference type="eggNOG" id="ENOG502S03Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GTYKYQH"/>
    <dbReference type="OrthoDB" id="496479at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="397"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="204"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="293"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="450" mass="48391" checksum="FCAE34481CB1FBC0" modified="2009-05-26" version="1">MRRRRASHPPAPPARRRRGQADVGAARPRPTSSVMASALIDEIKLNASNGDSEQYDLAGFTPGWLHDLVGSCLGTTLPAKSYVACKFVIGGGKKTRAKYDPDMLKHFTEALRAAGLEEDRGASACAECAGTYKYQHDTDKDLKYLHVFPKVEIVSVGGDGDGVNGGGDRTGGGNARSPEYQCCSCTFEEFIDLVAMNVPSFSQKRALLKRMRVLQSALEQLENMLVEQQRLTEQEQEMYDSMVDVSSKVDHLNAELEKMVSKGRLTKGEQKAMIGDLASKLEELDVMIATADAEGKQKKRETLEGKRVQLIEKSDAIASFKPIVYAMANERELNDLRAELKALEALEKASGGKLLKGADVAKLAKKPQIEERIAALEGEDKGWFEDECRAVLFTQKAPAPAKKKAASGGGGGGGNSSGWLTQAAKGGGRSAPAAKKTAPSNPFAALGGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N215</accession>
    <name>C1N215_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_10952</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062011.1">
        <property type="nucleotide sequence ID" value="XM_003061965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N215"/>
    <dbReference type="STRING" id="564608.C1N215"/>
    <dbReference type="GeneID" id="9687652"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_10952"/>
    <dbReference type="eggNOG" id="KOG3020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YGGSQKH"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005902-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="335" mass="36584" checksum="46027E5B8A60D1F5" modified="2009-05-26" version="1" fragment="single">RFVDIGANLTDAMFAGEYHGKRYHDADLPAVLRRAWNVGVEKIVVTAGTLEDATTALDLAEAHDGESSDEGAASSASASASSARLNQGRRRRRLYTTVGVHPTRCGAFEASGDAEAHLASLAAIASANSRERGGRVVAIGECGLDYDRLQFCDAETQRVWFRRQFELAKSTRLPMFLHMRAAADDFIEILAEAVAEGTFTTGVVHSFDGSVDDLKKLLAIDGVFIGVNGCSLRAAESLATLRELPVDRVMLETDAPWCGIKRSHAGYEHVRTTWTAKDKKKFDEFDETTTVKDRCEPCHVVQVLEVLSRAMGVDEDVLADACHANAMKVFFPDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2N5</accession>
    <name>C1N2N5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_41853</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EIF1AD family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062117.1">
        <property type="nucleotide sequence ID" value="XM_003062071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2N5"/>
    <dbReference type="STRING" id="564608.C1N2N5"/>
    <dbReference type="GeneID" id="9687346"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41853"/>
    <dbReference type="eggNOG" id="KOG2925">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PNRMQAP"/>
    <dbReference type="OrthoDB" id="1738325at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039294">
        <property type="entry name" value="EIF1AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641:SF0">
        <property type="entry name" value="RNA-BINDING PROTEIN EIF1AD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="5">
        <location>
            <begin position="3"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="150"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="210" mass="22808" checksum="06CEA5A1A17342FA" modified="2009-05-26" version="1">MSRRRKHVRNQLEELCPELNDGDAVCRVVELRGGNQVQVEKPDASTTLIRIPSKFSKVLWVRKGSHVLAHFEEDATSDAANGGARGSKVTGELLRVLYAEQIKELRRARPEAWPERFGTGRGGGGGADDDDGDAGVDDAVGGVRAMRFGDAAAEAEAEAEAEAEAEAEASDDDDGLPPLEANTNRRRMPESDSSSEEEEEVEEEEEDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N398</accession>
    <name>C1N398_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52089</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062571.1">
        <property type="nucleotide sequence ID" value="XM_003062525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N398"/>
    <dbReference type="GeneID" id="9687783"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52089"/>
    <dbReference type="OrthoDB" id="502714at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="437" mass="47892" checksum="6ED2F3A267D90761" modified="2009-05-26" version="1">MAGSLMGESSDEPPARGDGDESDDDGVDDDDLDNKLIDGVFALRLADEAHAKKTRAREAKALFWHDVYVFWTTALIAVPALVTVFALAIGAAAAEAEGWSFENGYLYVFSMLLDMPISLSDENPETKGGKATDIVAASWAWALLGAFIALVGNLNSIKRLAAAVEGFRVVWEKFFLCLCRVDRDADDGMEDLNAEESANIARVDELVESVDALVKKRAAADAAFVAAVRRKARFNLPAAARDARARREKRKDRRELSADVFTLVAGVFFVVPLLALGFSWALGAVFAEIEGWRTKIGFYYVLSQVFSRKNVYRTGPTTELPTGGLYYLRPTTTDGKIFGVFIALLAWSLIGTFVGIIVNLNVISRFVRWLESGGNRWRRLFKVKTPLEDFEGDASREDDVAMRDAARTLGEIHAEMTSARAELLGLIAAAGMPKNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3S4</accession>
    <name>C1N3S4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52280</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062665.1">
        <property type="nucleotide sequence ID" value="XM_003062619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3S4"/>
    <dbReference type="GeneID" id="9687865"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52280"/>
    <dbReference type="eggNOG" id="ENOG502T2QM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ADSWYGA"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="251" mass="26570" checksum="48CB983B742A9C4B" modified="2009-05-26" version="1">MRVEVFDATAVRAHVDEVRRVHAECFPGEVADDEPDAAFWDRVTACHDEDAITWFLLFDDDGPAIEAEGSAHEMIFDAKTSPPPPPPAPRPLIGFAAATPYTASLYGMHLGVTRPHRGRGHGAWIMREAQCWAHERGYPKVQATVERASTRLMKYYASLGATVVETGFGGGGGGGGGGEAGSIVRVERVFDEVIATTERDASRAHARALESSAAAAAAGSGAGTRRRRAAGSGAASFAAGAVVAMLLRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N432</accession>
    <name>C1N432_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52390</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062723.1">
        <property type="nucleotide sequence ID" value="XM_003062677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N432"/>
    <dbReference type="GeneID" id="9688163"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52390"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="403" mass="41272" checksum="27740648FE676B01" modified="2009-05-26" version="1">MGCGASKGADAPGTSPDASRKKNAKKKKKRGVEPPDADADDDEWWKPTTKLEEFNARLGETLATLARHAAAATVDASSSVAAAAAASSASSRRSTTVAIEFWSGDEEAEEEEDDESSSTAPRPRPNRAFATSCERGGVAAVAASLSSPATLVALRRVDLAILYDELRAGEKKDARGGGFVDADALASALRKIDRAEIAGTTADAAGDAFDDWTMKHALFRAVDEDGASVSRIADVVAAMQVLCGGGGGGAAAEKLRTAFEAHARDDDEAAAAAAAAGAKRGTLSKTRVMALLDGAVCAGVRAMRACLEDQTRRDALATRAVKSPTKRFMRRRLMNGAGGDGGGGGGDADDGEDDADAAPEPTVAVSIPTGEARAGAGAPGARAPSITLRRVLYTGPHTTAFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1N451</accession>
    <name>C1N451_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="11">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_29315</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="11"/>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062485.1">
        <property type="nucleotide sequence ID" value="XM_003062439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N451"/>
    <dbReference type="STRING" id="564608.C1N451"/>
    <dbReference type="GeneID" id="9688172"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29315"/>
    <dbReference type="eggNOG" id="KOG0351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CRWQFLL"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000296">
        <property type="entry name" value="ATP-dependent DNA helicase RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF153">
        <property type="entry name" value="RECQ-LIKE DNA HELICASE BLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="28"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="228"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="449"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="467"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH53304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="491" mass="53932" checksum="17414FB8249E5818" modified="2009-05-26" version="1">MDLCNKEVFGNEAFRSPQFSVASHAIRGGRGYAGRDCFVLMPTGGGKSLCYQLPAIITGGVTVVCSPLLSLIQDQVRHLVHDYDVPATYLSSAQTETDARAAFAELRKDKPTIRLLYVTPEKLASSDALWTCLEALYDSGQLARFVIDEAHCVSSWGHDFRPDYKKLGALKKRFPDTPVMALTATATMTVRADVLKSLGIARTARCFTVTFNRPNISLIVKHKKRMRDVSAFAKWVADRYGDKKAGIVYCLSRDETATLAAAINAERARRFKTGERPGPAAAAYNAGVPQKERTRIQNAWTAGDVRVCCATIAFGMGIDKPDVRYVVHYSAPKSLEGLYQEIGRAGRDGKEAEAVTLYAASDITRLRRINAMPQPGGGRRADRIKKSEPLLREVEAFLLNRVDCRRARLMSYLGEDGFEARRCGVTCDACARRAGIAGGLLGEEDTWDEDAKTDKVIRKPAGSGATTRRKKAAGGRKRKAKPKTTTRAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4D0</accession>
    <name>C1N4D0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52509</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062767.1">
        <property type="nucleotide sequence ID" value="XM_003062721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4D0"/>
    <dbReference type="GeneID" id="9688207"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52509"/>
    <dbReference type="eggNOG" id="ENOG502RYCV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KFFTGPP"/>
    <dbReference type="OrthoDB" id="5034579at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="782" mass="84178" checksum="1485AC5AB0956684" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4Q7</accession>
    <name>C1N4Q7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_42465</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCR4/nocturin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063039.1">
        <property type="nucleotide sequence ID" value="XM_003062993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4Q7"/>
    <dbReference type="STRING" id="564608.C1N4Q7"/>
    <dbReference type="GeneID" id="9688274"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42465"/>
    <dbReference type="eggNOG" id="KOG0620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CALFFDR"/>
    <dbReference type="OrthoDB" id="2866996at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF45">
        <property type="entry name" value="NOCTURNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="323" mass="35798" checksum="03BF53FE575541A0" modified="2009-05-26" version="1">MSRSTDTLSVIQYNVLADALSGPDAGFTSMPPCDLAFGARRAKLLGKIIAEDADVVCLQEVDHYHDAFKPAMDAAGYDGIYREDEWSPCRKLSGGMLRDGVAIFYKREKLQLCGMDLPGVPRRSKDVDDDKSLLGKCIDAGKCIVARFRVLPPREETHGPRWEEYQNSTLEVVVATVHLDSKKDEEGAKKRRNQAFHMMQAVEKMRSNSPTNFFLPVIVAGDFNAVPSEPAVDRVRNGVAGGLRSAYEEINGIHPAFTTWKIRSGNYKKGEAKMCIDYIFVPRECGILSVGALPDENDIGPKGLPCEKHPSDHLMLRADLKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4T7</accession>
    <name>C1N4T7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="9">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_49729</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the SHMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="9"/>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062849.1">
        <property type="nucleotide sequence ID" value="XM_003062803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4T7"/>
    <dbReference type="STRING" id="564608.C1N4T7"/>
    <dbReference type="GeneID" id="9688494"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49729"/>
    <dbReference type="eggNOG" id="KOG2467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TQPFFSQ"/>
    <dbReference type="OrthoDB" id="10265628at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000050">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF63">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="10">
        <location>
            <begin position="71"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH52788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="509" mass="55406" checksum="B0F92D7602A786CA" modified="2009-05-26" version="1">MAAITATPVVLSARARVAPSGSAVRAAAVVRPKLSKRSVTVFAKKGPEPPNAGAVAAETMRSAPFADTSVEELDPEMYAIMMKEKTRQRLGLELIASENFTSRAVMEVNGSCLTNKYSEGLPGKRYYGGNEFIDETERLCQDRALAAFRLPSDEWGVNVQVLSGSPANFAVYTALLNPHDRIMGLDLPHGGHLTHGFFTPKKKISATSIFFESMPYRLNEETGIIDYDQLEANAMLFRPKLIIAGASAYPRNYDYKRMREICDKVGAYLMSDMAHISGLVAAELVDDPFPYSDIVTTTTHKSLRGPRGGMIFYKKEFEQQINSAVFPGLQGGPHNHTIGALAVALKQAMTPEFIGYQKQVISNCATLANRLTELGYTLVSGGTDNHLILCDLRPMGVDGARVEYILDQAHITLNKNSVPRDTSALVPGGIRIGTPAMTTRGMLEDDFVKVADLIDEGVKIAIDCKAQAGGPKLADFKQYVQSTDRADIAALREKVESFAGDFHMPGGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4X2</accession>
    <name>C1N4X2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_42504</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Putative transcription factor.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063070.1">
        <property type="nucleotide sequence ID" value="XM_003063024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4X2"/>
    <dbReference type="GeneID" id="9688308"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42504"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044607">
        <property type="entry name" value="RKD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003035">
        <property type="entry name" value="RWP-RK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373">
        <property type="entry name" value="PROTEIN RKD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373:SF2">
        <property type="entry name" value="RWP-RK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02042">
        <property type="entry name" value="RWP-RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51519">
        <property type="entry name" value="RWP_RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RWP-RK" evidence="8">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="194" mass="22185" checksum="6961F86E38D5DB6E" modified="2009-05-26" version="1">MTKTSLASVALLTEAEAARAFNMGTTRFKARCRTLGIARWPYRKLMSLKNLYYDLTVHLKRALDGNDVDMEERARAMMEEIKTYAALLESDLSLLNSFYNGKKAWPDHILKIRQTIYKKRHAEVLVNKKIAAKNAKSEQVAARAFSDASDFDSRDDDRLSDDDSMQTDRDGAGIEEYAHEWWQLALEEPNFAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4Z5</accession>
    <name>C1N4Z5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-mRNA-splicing factor 18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_4900</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063082.1">
        <property type="nucleotide sequence ID" value="XM_003063036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4Z5"/>
    <dbReference type="STRING" id="564608.C1N4Z5"/>
    <dbReference type="GeneID" id="9688522"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4900"/>
    <dbReference type="eggNOG" id="KOG2808">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANEAYMM"/>
    <dbReference type="OrthoDB" id="10261918at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071021">
        <property type="term" value="C:U2-type post-spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000350">
        <property type="term" value="P:generation of catalytic spliceosome for second transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004098">
        <property type="entry name" value="Prp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039979">
        <property type="entry name" value="PRPF18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007:SF19">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02840">
        <property type="entry name" value="Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47938">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Prp18" evidence="8">
        <location>
            <begin position="7"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="157" mass="18129" checksum="EA244DB058A633A9" modified="2009-05-26" version="1" fragment="single">IDQVGAYFKSLLEEWERELEAKPEEWIYTEEAKLQVANVRLCRNHMKPLFKRIKRRQLPGDIERALFLMVQAMKARNYRQAADVYVGVAIGNAPWPIGVTSVGIHERSAREKIGAQSQAHAMHDEETRKYLQSVKRLITFAQRSYPTVPSLSLDFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N500</accession>
    <name>C1N500_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_52740</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062882.1">
        <property type="nucleotide sequence ID" value="XM_003062836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N500"/>
    <dbReference type="STRING" id="564608.C1N500"/>
    <dbReference type="GeneID" id="9688322"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52740"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="167" mass="18843" checksum="88F6F0C46E4FBB19" modified="2009-05-26" version="1">MQKRSTSDGFNDIPENVAAVVFSHLGKNPRHRIRLAAVSKVWRDAKKSDLSLPGAPRALFELGEDLIGKETKVSFRKAFYWYRKAADLGDADAMWMIGVCYRSGLGVKKDKTKAFEWWEKASLWCFHRKAICSLAMCYQRGDGVEKNKAMAFELYLRAAEQGSAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N521</accession>
    <name>C1N521_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_48723</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062895.1">
        <property type="nucleotide sequence ID" value="XM_003062849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N521"/>
    <dbReference type="STRING" id="564608.C1N521"/>
    <dbReference type="GeneID" id="9688532"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48723"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="277" mass="28854" checksum="71D03C9194A89F25" modified="2009-05-26" version="1">MRLALPALRSAASTASRRSASRAAATVRGAPSTAAAAAAMRRRGRGISNGRRGRRGISLFSATASSSSSSSSSTPASSIYGNPALYELAFGFRDFDDEVAFVKRVSETLGVGAFRSMLELGAGPAWHTTSAASIDGVRAVAVDLDAAMVTRANERIEEAGLGSRATAMRGDMIRLDVDATRRALAEMMGGPGGGASDESDGFDAACVLLGTAAHLVETADAIATFESIGRCLKPGGVCVLELEHPYDLFDGGLLGASFFSTRHWSPYDRVRVVNFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N583</accession>
    <name>C1N583_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Superoxide dismutase copper chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_52844</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063126.1">
        <property type="nucleotide sequence ID" value="XM_003063080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N583"/>
    <dbReference type="STRING" id="564608.C1N583"/>
    <dbReference type="GeneID" id="9688566"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52844"/>
    <dbReference type="eggNOG" id="KOG4656">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HTEPLGG"/>
    <dbReference type="OrthoDB" id="666972at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006801">
        <property type="term" value="P:superoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="5">
        <location>
            <begin position="64"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="350" mass="35877" checksum="34A79848D122F144" modified="2009-05-26" version="1">MSAASCVSRAAVAVAPRAPPRASSSRRPTTRRVRAPPPRRDASASATESTAAESTTAAEEAPVARSLEFMVEMACGKCVAKVEHALAHVPGIDAVAATLSTNSVRVVTATASTDAIVAAIERAGFNCRLIGQGDVGAFGEELARRLGTNLRTLRQSLAAVAEFKGSAYGHGSIAGVVRFVAADERNTLIEGGLRGLKPFATYAMTVRAYGDTTRGLETVGEVYDAADDDGDDSSENARRAAGDMGTLVADANGEVTIVSRVVDARLKAWDIIGRSLAVVEQGGGGGGGGGEDGTSTGAAAVLARSAGVGENLKRVCDCDGTVIWESSPDDFTPVVVKKKLVTAVVEKKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N590</accession>
    <name>C1N590_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_21938</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062926.1">
        <property type="nucleotide sequence ID" value="XM_003062880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N590"/>
    <dbReference type="GeneID" id="9688570"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21938"/>
    <dbReference type="eggNOG" id="ENOG502S4CZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TNAMLMQ"/>
    <dbReference type="OrthoDB" id="9989223at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051082">
        <property type="entry name" value="Pentapeptide-BTB/POZ_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14136">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14136:SF17">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="182" mass="19948" checksum="0BBF3E890EC90728" modified="2009-05-26" version="1">MNLKLKPREQEVILETKAEHVNEDFSHSDLVGAIYTEGDLRGSDFSGSDLRAAIFSRAIMPGVNLEGSDMQNAFLDYVVLRGANMRGVIASGANFVRSDLGDVDVTNADFTEAVIDRYQARSISHWSPYDPLCDGASGVNEFTGVDTRDSLGCDRLKRYEGFNKENDKVKVSKESGTWGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5I5</accession>
    <name>C1N5I5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_29577</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063164.1">
        <property type="nucleotide sequence ID" value="XM_003063118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5I5"/>
    <dbReference type="STRING" id="564608.C1N5I5"/>
    <dbReference type="GeneID" id="9688604"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29577"/>
    <dbReference type="eggNOG" id="KOG1119">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PLIRYFW"/>
    <dbReference type="OrthoDB" id="4518at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044200">
        <property type="entry name" value="At5g03900-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47380">
        <property type="entry name" value="OS02G0533000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47380:SF4">
        <property type="entry name" value="OS02G0533000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="553" mass="58394" checksum="10B9057B0F2921EA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5N2</accession>
    <name>C1N5N2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">60S ribosomal export protein NMD3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_22366</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NMD3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063187.1">
        <property type="nucleotide sequence ID" value="XM_003063141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5N2"/>
    <dbReference type="STRING" id="564608.C1N5N2"/>
    <dbReference type="GeneID" id="9688832"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22366"/>
    <dbReference type="eggNOG" id="KOG2613">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VILVRKH"/>
    <dbReference type="OrthoDB" id="203821at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039768">
        <property type="entry name" value="Nmd3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007064">
        <property type="entry name" value="Nmd3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048899">
        <property type="entry name" value="NMD_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048898">
        <property type="entry name" value="OB_NMD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746:SF2">
        <property type="entry name" value="60S RIBOSOMAL EXPORT PROTEIN NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04981">
        <property type="entry name" value="NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21193">
        <property type="entry name" value="NMD_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21192">
        <property type="entry name" value="OB_NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nmd3 N-terminal" evidence="9">
        <location>
            <begin position="15"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 SH3" evidence="11">
        <location>
            <begin position="251"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 OB-fold" evidence="10">
        <location>
            <begin position="316"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="516"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="526"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH52323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="549" mass="61527" checksum="1E76B0D7276A9CDF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5U1</accession>
    <name>C1N5U1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_53039</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063425.1">
        <property type="nucleotide sequence ID" value="XM_003063379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5U1"/>
    <dbReference type="STRING" id="564608.C1N5U1"/>
    <dbReference type="GeneID" id="9688654"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53039"/>
    <dbReference type="eggNOG" id="KOG1589">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FWAPIVK"/>
    <dbReference type="OrthoDB" id="869189at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="112" mass="12361" checksum="B6DBC4F5415FC4C4" modified="2009-05-26" version="1">MASGLFAAVNNFINHPAGPKTIFFWAPTMKWGITAANVKDFSRPPELLSYGQQSAVAVTGIIWCKYALDITPKNYNLMSVNVVMASTGLYQLYRKFEHERRTSAEAGANKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N673</accession>
    <name>C1N673_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53180</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063486.1">
        <property type="nucleotide sequence ID" value="XM_003063440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N673"/>
    <dbReference type="GeneID" id="9688725"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53180"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="168" mass="17774" checksum="475380A44F3408D8" modified="2009-05-26" version="1">MTKRATRAAKRRDVSPPSPSSEQDLSFGDVHDGDGDAPTGEKSIKDVLRQLDARADATVERAALSMNVVAEDAEEAATDARDQAAGAIAHCKKVLLGPARSVVADLTARSESLLDVLKETIAGTEREHAKDAAALKEELFNLADAVGLRAVSDVYSEGQRATLADESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6Y4</accession>
    <name>C1N6Y4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Phosphofructokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PFK</name>
        <name evidence="13" type="ORF">MICPUCDRAFT_53485</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063812.1">
        <property type="nucleotide sequence ID" value="XM_003063766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6Y4"/>
    <dbReference type="STRING" id="564608.C1N6Y4"/>
    <dbReference type="GeneID" id="9689075"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53485"/>
    <dbReference type="eggNOG" id="KOG2440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DYCIGFS"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.450:FF:000002">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050929">
        <property type="entry name" value="PFKA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005301">
        <property type="entry name" value="PRK06830.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45770">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="12">
        <location>
            <begin position="216"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH52185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="567" mass="59992" checksum="B982E7423CBD5B90" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7A6</accession>
    <name>C1N7A6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_4429</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063864.1">
        <property type="nucleotide sequence ID" value="XM_003063818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7A6"/>
    <dbReference type="STRING" id="564608.C1N7A6"/>
    <dbReference type="GeneID" id="9689305"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4429"/>
    <dbReference type="eggNOG" id="KOG1132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="497061at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990918">
        <property type="term" value="P:double-strand break repair involved in meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF47">
        <property type="entry name" value="FANCONI ANEMIA GROUP J PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent helicase C-terminal" evidence="1">
        <location>
            <begin position="72"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="256" mass="29024" checksum="2F77C7FF61973ED7" modified="2009-05-26" version="1" fragment="single">SLESELGVEFPVKVEAPHIVPRRQLHVEASDALGDFTRKTQESDKMPGNLGSLLLKYVKVTPGGVLVFLPKYSLIQRVIDEWAHTGMLEELEKHKRVVYEEPGAETLAPTMETFKDAIESGRGGVFLAVYRGKVSEGLDFKDANARAVFCVGIPFPSLGDVKVKLKREYNNHVESKKQGLMSGGEWYTHQAFRAYNQALGRCVRHQFDYACIFLVDARFCMHDEASHNKRMVSKWMRNLVTHYSQSRESVGTVREF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7B1</accession>
    <name>C1N7B1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53623</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063706.1">
        <property type="nucleotide sequence ID" value="XM_003063660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7B1"/>
    <dbReference type="STRING" id="564608.C1N7B1"/>
    <dbReference type="GeneID" id="9689147"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53623"/>
    <dbReference type="eggNOG" id="KOG3222">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FPGPYCK"/>
    <dbReference type="OrthoDB" id="6288734at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009143">
        <property type="term" value="P:nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="RdgB/HAM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067:SF9">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="263" mass="29297" checksum="88CAEF33C9A606F1" modified="2009-05-26" version="1">MADKPFKILYCTGNHGKFAEAKCVIDEYNTLGADVDKLRWVEIQRVDADPVEVQGSQVEIATRKVKEAVKIFHETGRGREVLEGADFLVTEDVGLALQCLNGFPGPYCKSMLERVGPEGLWNLCSRYEDRSCLVTCTLAAIDLRGGRFHWEESIKNARTFVGELVGCISGPPRGSVMHGKASWNSVFTPAGYDQTFGEMSYAKQASFSHRRMAILKFLDAYCPRTEGQCMGGRNYLPGVKRVTGDDAARILADRERQQRSVPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7B7</accession>
    <name>C1N7B7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53630</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063870.1">
        <property type="nucleotide sequence ID" value="XM_003063824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7B7"/>
    <dbReference type="GeneID" id="9689311"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53630"/>
    <dbReference type="OMA" id="NASAERC"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047137">
        <property type="entry name" value="ORF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33824">
        <property type="entry name" value="POLYKETIDE CYCLASE/DEHYDRASE AND LIPID TRANSPORT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33824:SF7">
        <property type="entry name" value="POLYKETIDE CYCLASE_DEHYDRASE AND LIPID TRANSPORT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="303" mass="34230" checksum="3604A608DE62C24E" modified="2009-05-26" version="1">MTNDAIAPAERAEERLLALAERGAIRGSRSEEDRRWRAAMAKASPDEFWEWQREDEWWAQHAKWSEAAYAPARKKYADVVSEFVAGVDVNASAERCFRLWRDPDALRKFVPGLAAIRPAPDGRCFECKQLYQFADPRTHELEELWFMTHIAEEMENRSIHYQATDGFPNGVVVTFDASEENASWTSVNVEYYCHLPMDLAVKDGVMRVSLDVEGLVTECLTRFAKLAAAADGDDGDDDDEIFPARALPVGSGLRGKDGREVQRGEPTVASKRAMREAREAFVKRVGREPFKTELLKGETRGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N817</accession>
    <name>C1N817_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_49762</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064190.1">
        <property type="nucleotide sequence ID" value="XM_003064144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N817"/>
    <dbReference type="GeneID" id="9689446"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49762"/>
    <dbReference type="OMA" id="AATHNRI"/>
    <dbReference type="OrthoDB" id="496373at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="257" mass="27800" checksum="EA620BFAEDECED97" modified="2009-05-26" version="1">MAMTLDNPSKMDPGKVPALVMRSVENATTALRDGDADRAIKMMLSTDELCHKVIAPPTIHGLAMRVLSDAYLAKDNMEDAKKALEKGLSLCKPHDGRANMPPFMKADLNGRMGDLLVALGEVENAMGDHKKAVQHMRQGAERFEVLGQQEFVAATHNRIALTLLQAGKHELALAAVLDAEKLAGELGEGNEHEANILSTTFCYKGRCSVMAGNIDGAREAMTQALRYAMASGNDKVKEEAETFLAEHPSKVDEAAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N883</accession>
    <name>C1N883_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53986</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064224.1">
        <property type="nucleotide sequence ID" value="XM_003064178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N883"/>
    <dbReference type="GeneID" id="9689478"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53986"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="609" mass="66729" checksum="2AD90E9CE505B663" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N899</accession>
    <name>C1N899_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54006</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064232.1">
        <property type="nucleotide sequence ID" value="XM_003064186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N899"/>
    <dbReference type="GeneID" id="9689673"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54006"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="193" mass="21442" checksum="4BC4BCCB75C06C80" modified="2009-05-26" version="1">MPPKRKPKPPPPPPVEISSAPLEDEDDATVVVVATVAADDDGDVMKSHRLSTPRVSSREMTAFEDAPLAKPKPSAPPLVAPVTPTPTTPAPPSSKKPRIDTSAITGVRVIACLAVLCQHWIQWYGKKSHGEIELQVRVASYRSTPIHIPRERPRARRDGRDRRRRRRRRRRPRVVGRAVRRIASRGIDSFSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8I9</accession>
    <name>C1N8I9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_7632</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064274.1">
        <property type="nucleotide sequence ID" value="XM_003064228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8I9"/>
    <dbReference type="STRING" id="564608.C1N8I9"/>
    <dbReference type="GeneID" id="9689534"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7632"/>
    <dbReference type="eggNOG" id="KOG0846">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="361383at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="76"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="19191" checksum="2565D16B782D6A97" modified="2009-05-26" version="1" fragment="single">ISLSNLKDNPGSKTWRLRVGRGRGGGMGKTARRGYNGQKSRSGGAPRIGFEGGQTPLRLTLPKRGFVNPKRMVFTPLNLWKLQKWIDDGRLDVSKTLTMKDFVDARLIDPRVKNGLKLLAKEMDGHAFTAKINVEVSRVSAAAKEAIEKNGGSVVTVHYNRLGLRALFYPQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N917</accession>
    <name>C1N917_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54327</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064537.1">
        <property type="nucleotide sequence ID" value="XM_003064491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N917"/>
    <dbReference type="GeneID" id="9689978"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54327"/>
    <dbReference type="OrthoDB" id="6359943at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="97" mass="10896" checksum="76BB4B1742591FE0" modified="2009-05-26" version="1">MGFNCFARFCLPWRSNLTFGLASLALTTFYFVRYMQYALRASERGILDEGVFGFNDVVRTGLFMAVTHFYAMVGGSHVRSISHWSPYDPVGAVNAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N990</accession>
    <name>C1N990_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43506</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064409.1">
        <property type="nucleotide sequence ID" value="XM_003064363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N990"/>
    <dbReference type="GeneID" id="9690021"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43506"/>
    <dbReference type="eggNOG" id="ENOG502QVT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FASPMNA"/>
    <dbReference type="OrthoDB" id="546970at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016422">
        <property type="term" value="F:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099122">
        <property type="term" value="F:RNA polymerase II C-terminal domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039881">
        <property type="entry name" value="PCIF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022035">
        <property type="entry name" value="PCIF1_WW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21727:SF0">
        <property type="entry name" value="MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21727">
        <property type="entry name" value="PHOSPHORYLATED CTD INTERACTING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12237">
        <property type="entry name" value="PCIF1_WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCIF1 WW" evidence="2">
        <location>
            <begin position="227"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="385" mass="41003" checksum="D55AD641CE81A0BB" modified="2009-05-26" version="1">MRTREGNRAVTKDARRAVELECARASALDRCRKKYEKMATNAGAGAAPPQGFERWRFAAKAAEDRAARRCGGGEGGGGGGARLDPALPSSDAAALALDVLVADLTRAGVKDADKAASIARDVADAAAREARALAKLELRLAAGKGGARATSSSDASAPATNDDVVARRRKHSVELTSRGKFVVTSRAAYARLRALYREHAPPCDGPAISEDSEEDDEGDDRDRFSSLAEKAFHRRLFALLLRYKSIHGYGFQASVGEEVFRALGAKLGVAHECFASPMNAHYGAFNGAFLDVDAPFGSAGDFFAVADRGGFRRGAYEANPPFVSGVMDAMVDAMELALTRADADAQPLTFAVFVPGWSDEPCWAKARPTSRRFPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9U4</accession>
    <name>C1N9U4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54638</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064675.1">
        <property type="nucleotide sequence ID" value="XM_003064629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9U4"/>
    <dbReference type="GeneID" id="9690236"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54638"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="213" mass="22131" checksum="7D5237E4222CFA94" modified="2009-05-26" version="1">MGEENPWTIAGGVRIAGARRKTASGSDASVRASLRVSLDSSSFASSGSPIDASDDAINIIAAVSASSPLRTLVPGNVSLHRAAEAELAARKARDIAGAGASGRGRGRQRAAFEGRAKKAPSAEEAIVTNESPPRRTRDADAADAPPPSPPPPPSPGLFRVASLPPPPSPTSEARARVARRRHRKRLAQIVVGQARPNSHWSPYDPVRDVNAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA41</accession>
    <name>C1NA41_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54752</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064843.1">
        <property type="nucleotide sequence ID" value="XM_003064797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA41"/>
    <dbReference type="GeneID" id="9690165"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54752"/>
    <dbReference type="OMA" id="HAVITWA"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="283" mass="29963" checksum="1092CEF24C6A10F2" modified="2009-05-26" version="1">MQIGRTRTSQLHVKGDPAVSQKHAVITWAYDQWWIQDVGSSNGTAINGEELEPDDSPTGLRDGDVLTIGTDTTAKVTIVKAAAAAEGPRNGGGAAKKRKPAAKKASVKEKEDAAAAAEEAPKKAPAKRRGRPPKKKPEPEPEPEVEPEESAAAAAEPEPEKPRTTKARAKPAANKPAAPEPEIVATTEAAAAAEEEEEEEEDEDDEDNKENAPAAPPLETVEDYVRATCDALVDDVKREIFAVVKRLKDDAEGIKSELRGLVDDPEGLARVAAEAPPAVEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA44</accession>
    <name>C1NA44_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54755</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064845.1">
        <property type="nucleotide sequence ID" value="XM_003064799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA44"/>
    <dbReference type="GeneID" id="9690286"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54755"/>
    <dbReference type="OrthoDB" id="60822at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="70" mass="7325" checksum="33FA1407F3D0A0E4" modified="2009-05-26" version="1">MVQEREGDGATSARDGSFEVTHEDDTVLFSKLKEGRLPRPEEILEALEKKFEADGVDAMGGGGLGGAGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRC7</accession>
    <name>C1KRC7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Small ribosomal subunit protein uS19c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rps19</name>
        <name evidence="9" type="ORF">MicpuC_chl26</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="9"/>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRC7"/>
    <dbReference type="STRING" id="564608.C1KRC7"/>
    <dbReference type="OMA" id="KGPFVDP"/>
    <dbReference type="OrthoDB" id="2043at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_uS19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF8">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACO50759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="92" mass="10368" checksum="FA1600ADC17FF8C9" modified="2009-05-26" version="1">MARSLKKGPFVAHKLMKKIEALHAKGEKSVIQTWSRGSTITPIMIGHTIAVHNGREHIPVFVTDQMVGHKLGEFSPTRTFRGHVKTDKKSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGN3</accession>
    <name>C1MGN3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_12936</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054807.1">
        <property type="nucleotide sequence ID" value="XM_003054761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGN3"/>
    <dbReference type="STRING" id="564608.C1MGN3"/>
    <dbReference type="MEROPS" id="S14.010"/>
    <dbReference type="GeneID" id="9680607"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12936"/>
    <dbReference type="eggNOG" id="KOG0840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MYTAFTG"/>
    <dbReference type="OrthoDB" id="2017408at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF11">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="210" mass="22439" checksum="CC3792948233016B" modified="2009-05-26" version="1">MKPRAEKLGDPPVNVAVRTSGGEMIDCFTALERNRVIFIGDRIDEDVATSVCAKLLALQYDAPDKDITIFLNCTAGTQYCVTTILDMMDYVSNDISVVAMGCVAGPPAMLLAGATKGKRLALPSARIILSQPLGGLSGTSYEVKIQAKELSRNARSQVAFFAKFTGKSFEDMGEYLVRDTYMSPKEAMEINLIDGEIGVDAKIGGIAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGS9</accession>
    <name>C1MGS9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein CS051</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CS051</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_70660</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNAAF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054829.1">
        <property type="nucleotide sequence ID" value="XM_003054783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGS9"/>
    <dbReference type="STRING" id="564608.C1MGS9"/>
    <dbReference type="GeneID" id="9680780"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70660"/>
    <dbReference type="eggNOG" id="ENOG502QT97">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HIFESTM"/>
    <dbReference type="OrthoDB" id="538817at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070286">
        <property type="term" value="P:axonemal dynein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044458">
        <property type="term" value="P:motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039304">
        <property type="entry name" value="DNAAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028235">
        <property type="entry name" value="DNAAF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22118">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR 3, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22118:SF14">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14740">
        <property type="entry name" value="DUF4471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4470" evidence="6">
        <location>
            <begin position="11"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein assembly factor 3 C-terminal" evidence="7">
        <location>
            <begin position="172"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="500"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="552" mass="61272" checksum="6D6505E2C9DF4F79" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGT0</accession>
    <name>C1MGT0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spindle assembly associated Sfi1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SFI1</name>
        <name evidence="2" type="ORF">MICPUCDRAFT_70661</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055374.1">
        <property type="nucleotide sequence ID" value="XM_003055328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGT0"/>
    <dbReference type="GeneID" id="9680634"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70661"/>
    <dbReference type="eggNOG" id="ENOG502SCUZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PLECERS"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="774"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1073" mass="123229" checksum="8F563FA0FF443520" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH19</accession>
    <name>C1MH19_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50019</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054876.1">
        <property type="nucleotide sequence ID" value="XM_003054830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH19"/>
    <dbReference type="STRING" id="564608.C1MH19"/>
    <dbReference type="GeneID" id="9681009"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50019"/>
    <dbReference type="eggNOG" id="KOG4254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AFMFADW"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016116">
        <property type="term" value="P:carotenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045892">
        <property type="entry name" value="CrtISO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313:SF6">
        <property type="entry name" value="FAD_NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="113"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="646" mass="68115" checksum="8C8E679E947DA120" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHA8</accession>
    <name>C1MHA8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rav-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_50111</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054924.1">
        <property type="nucleotide sequence ID" value="XM_003054878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHA8"/>
    <dbReference type="GeneID" id="9680935"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50111"/>
    <dbReference type="OMA" id="ENAWSAS"/>
    <dbReference type="OrthoDB" id="1932364at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050913">
        <property type="entry name" value="AP2/ERF_ERF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31194:SF140">
        <property type="entry name" value="ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR CRF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31194">
        <property type="entry name" value="SHN SHINE , DNA BINDING / TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="79"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="191"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="278"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="354"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="397" mass="41778" checksum="FF6F8846B9E041D8" modified="2009-05-26" version="1">MPTFKHTGSPPPPSSPSAAAGDVDASAPPEVDDHYRNTIEQLKRDIDAAPPRPKDADGAAGGKPTSSYPATNQNNPRSGFRGVSQKSLNCYGASVYVSRLNRNVFLGVFPSAELAARMYDAAATIVFGPDAYVNFPGSATHEPPTGAQVAAMKLKVTGGRTASCKECGQELPVKTRVCGRCRAPVKFKDVPFKGVRVKLRGNNQPRYQAVFCLKGKVEFIGTFRTQEEAARAYDARAREAYGDEEGRTNFATTAEADAACEVGLRKLSAAGGDLAPIVTKRKSERKSDGDDSDDELELRRRKKRRREEKASGGGNGGGGNGGGGKGKGGGSGRGRRSNYYDRLLVSGGGGFVDADERAWGGGAGNDLSSTGGLDFSVAPPKQRKGGKSIAEQLLGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHK4</accession>
    <name>C1MHK4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_12446</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054969.1">
        <property type="nucleotide sequence ID" value="XM_003054923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHK4"/>
    <dbReference type="STRING" id="564608.C1MHK4"/>
    <dbReference type="GeneID" id="9680693"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12446"/>
    <dbReference type="eggNOG" id="KOG0272">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TCKLWEA"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="115"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="157"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="200"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="242"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="284"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="326"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="368"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="410"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="443" mass="48097" checksum="D3242200C330B6C5" modified="2009-05-26" version="1">MSARGFSGGGRSLEEAQQRAATASSRVKLKKFLLRYYPPGIILEYTHNGELMQRSVDLLDLTAETDTEAVLNQIVEREKMIKEAHREPLRKLIFKLQAKLGGGVVKTNFALSKVLRAHILPLTNCAFNKGGDKFITGSYDRTCKVWSTDTSEELQTLEGHKNVVYAIAFNNPYGDRVLTGSFDKTAKLWDASTGQLYHTMNSHTAEIVCVGFNQQSTTYATGSMDNSAKLTDVETGAEICTLLGHSAEIVALHWSTAGDQLCTASFDHESRVWDARTGRCVHVLSGHTSEVSSAQWNFSSDAIVSGSIDGTAKIFDVRAGECRATLTGHADEVLDVVFNATGTKVATASADCTAKLWNVSSGRCEATLSGHSQEVSKVSFRPQGDRVFTASADSTAKVFDVNGGKCLQTLEGHGDEIFSLASNYHGDVLLTGSKDNTCRIWKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHY2</accession>
    <name>C1MHY2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_50364</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055569.1">
        <property type="nucleotide sequence ID" value="XM_003055523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHY2"/>
    <dbReference type="STRING" id="564608.C1MHY2"/>
    <dbReference type="MEROPS" id="T01.977"/>
    <dbReference type="GeneID" id="9680630"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50364"/>
    <dbReference type="eggNOG" id="KOG0184">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RVSMYMH"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03751">
        <property type="entry name" value="proteasome_alpha_type_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000007">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="255" mass="27672" checksum="7053AB2B600178B2" modified="2009-05-26" version="1">MSGIGTGYDLSTTTYSPDGKVFQVDYAGKAVDNGGLALGIKCKDGVVLGVEKLLAFKMLVPGSNRRIAAVDRHAGMAGTGLAPDARAIVTRARQECAQYLSFYGDRIPAKILADRMAHYLHMFTLYWSVRPFGASTLLAVKDHELGYALYLLEPSGEVQRYFGTAVGKGRQAAKNEIEKLVKADAAGSLSCRDAVKHLARIVYSTHDEKDKAFECELSWICDQSGGEFRRVPKELAEEAITLAKAALEDDDMADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJM3</accession>
    <name>C1MJM3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_71044</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055844.1">
        <property type="nucleotide sequence ID" value="XM_003055798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJM3"/>
    <dbReference type="GeneID" id="9681875"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_71044"/>
    <dbReference type="eggNOG" id="ENOG502T14R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PNQHTHV"/>
    <dbReference type="OrthoDB" id="10632999at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="617"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="818"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="843"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1058" mass="111809" checksum="BF208DB89DC60274" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKF6</accession>
    <name>C1MKF6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Inositol-pentakisphosphate 2-kinase</fullName>
            <ecNumber evidence="1 6">2.7.1.158</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_64376</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20313"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57733"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.158"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="6">The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.158" evidence="1 6"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055988.1">
        <property type="nucleotide sequence ID" value="XM_003055942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKF6"/>
    <dbReference type="STRING" id="564608.C1MKF6"/>
    <dbReference type="GeneID" id="9681947"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64376"/>
    <dbReference type="eggNOG" id="KOG4749">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CLHSRTI"/>
    <dbReference type="OrthoDB" id="272370at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035299">
        <property type="term" value="F:inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.110">
        <property type="entry name" value="Inositol-pentakisphosphate 2-kinase, N-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009286">
        <property type="entry name" value="Ins_P5_2-kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043001">
        <property type="entry name" value="IP5_2-K_N_lobe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14456">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14456:SF2">
        <property type="entry name" value="INOSITOL-PENTAKISPHOSPHATE 2-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06090">
        <property type="entry name" value="Ins_P5_2-kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="512" mass="57991" checksum="EEAE3BE9DB7A45E1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKP5</accession>
    <name>C1MKP5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_64527</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056422.1">
        <property type="nucleotide sequence ID" value="XM_003056376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKP5"/>
    <dbReference type="GeneID" id="9681353"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64527"/>
    <dbReference type="eggNOG" id="KOG2132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="496616at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF105">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="375"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="533" mass="59998" checksum="BB55B633474270DA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKR0</accession>
    <name>C1MKR0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_64553</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056040.1">
        <property type="nucleotide sequence ID" value="XM_003055994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKR0"/>
    <dbReference type="STRING" id="564608.C1MKR0"/>
    <dbReference type="GeneID" id="9681358"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64553"/>
    <dbReference type="eggNOG" id="KOG0910">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NIVATRI"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000001">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663:SF11">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="57"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="163" mass="17730" checksum="3181F729E6F586DE" modified="2009-05-26" version="1">MFSTTSNSIHIPKISASASFRNSSRNRRLSNSARPCGRYGISARRYVAVRAEEVTTSGVPTVVTDATFESEVLQSEVPVLVDFWAPWCGPCRMIAPLIDQLAEEYAGKLKAVKLNTDESPSVATEYGIRSIPTVMIFKGGQKLDTVIGAVPKSTLTGTIEKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML10</accession>
    <name>C1ML10_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_6230</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056476.1">
        <property type="nucleotide sequence ID" value="XM_003056430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML10"/>
    <dbReference type="STRING" id="564608.C1ML10"/>
    <dbReference type="GeneID" id="9681386"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6230"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RNSHEHE"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="157" mass="17321" checksum="93398FCC75E73B9C" modified="2009-05-26" version="1" fragment="single">SQIATGMSYLMHLGVIHGDLKASNVLLHPDKGRVSNWCAKIADFGSANLLHPPETFTLMSRVNGTVSHMAPELLKDRRASHASDVYSFAIVLWEIMARGAAAFEGVTPVNIIVAVTRHDLRPLFPRLTFSPVLNLATRCWQADYASRPSFHKIVSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLB5</accession>
    <name>C1MLB5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_55656</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="3"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056532.1">
        <property type="nucleotide sequence ID" value="XM_003056486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLB5"/>
    <dbReference type="STRING" id="564608.C1MLB5"/>
    <dbReference type="GeneID" id="9681578"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55656"/>
    <dbReference type="eggNOG" id="ENOG502SB96">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DRFWENG"/>
    <dbReference type="OrthoDB" id="42736at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057027">
        <property type="entry name" value="TPR_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23276">
        <property type="entry name" value="TPR_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="10" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="PPR" evidence="9">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="12">
        <location>
            <begin position="356"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="356"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH59908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="839" mass="94215" checksum="2DFCA1ADB884DD47" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLE0</accession>
    <name>C1MLE0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_70834</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056549.1">
        <property type="nucleotide sequence ID" value="XM_003056503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLE0"/>
    <dbReference type="STRING" id="564608.C1MLE0"/>
    <dbReference type="GeneID" id="9682027"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70834"/>
    <dbReference type="eggNOG" id="KOG2024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WASAMLD"/>
    <dbReference type="OrthoDB" id="408320at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005990">
        <property type="term" value="P:lactose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000018">
        <property type="entry name" value="Beta-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF2">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="LacZ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta galactosidase small chain/" evidence="7">
        <location>
            <begin position="709"/>
            <end position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1036" mass="115961" checksum="B66A7229AC7F2B3E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLM4</accession>
    <name>C1MLM4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_55767</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056192.1">
        <property type="nucleotide sequence ID" value="XM_003056146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLM4"/>
    <dbReference type="STRING" id="564608.C1MLM4"/>
    <dbReference type="GeneID" id="9681851"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55767"/>
    <dbReference type="eggNOG" id="KOG4675">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CLTYEIN"/>
    <dbReference type="OrthoDB" id="1737049at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.40">
        <property type="entry name" value="ENT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033485">
        <property type="entry name" value="EMSY-LIKE_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005491">
        <property type="entry name" value="ENT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036142">
        <property type="entry name" value="ENT_dom-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33432:SF22">
        <property type="entry name" value="OS10G0436850 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33432">
        <property type="entry name" value="PROTEIN EMSY-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03735">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01191">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158639">
        <property type="entry name" value="ENT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51138">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENT" evidence="3">
        <location>
            <begin position="5"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="270" mass="30135" checksum="434CD488B1657B19" modified="2009-05-26" version="1">MGMGVGEQVRKIEIDAYTMFMKATAITGMSWDRDELATKLRRELNVSNDDHTRIREKLSEDERVSNLREAWISRQAMHAAKKARVDHIVSPAGNLATKKSPGHSTLKQFSKQQRFATGGTSMMVDNLICRKVQRFWPEEGGWFDAIITDYRPTTQEHCLTYEINTESETFEWANLTAFNAKEFKILEERVAIEDLKFFCEGMKPGAEMATHNSALAQTHAAVGGVNSLAKKALKTADAGKIFEAKGTLSAQEVALKAQLAALDDSESDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMB8</accession>
    <name>C1MMB8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_56470</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057376.1">
        <property type="nucleotide sequence ID" value="XM_003057330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMB8"/>
    <dbReference type="GeneID" id="9682815"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56470"/>
    <dbReference type="eggNOG" id="ENOG502RZ7K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GAYMLNA"/>
    <dbReference type="OrthoDB" id="153646at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="4">
        <location>
            <begin position="4"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="423" mass="43403" checksum="9ABD125E79347F1C" modified="2009-05-26" version="1">MVVGYAWAFSAAVAQSGSDILRKLGTKNKRFSSNLELVTAWEFTNCVVLACAMLLRGATPAVRRGFEDLQLVAVAGLSGLAKIGCSVLFQRALTLSPVSLSVPYLAFTPALLLFTSYWTLGEKPNAYGVAGVTVLAAGAYALNAVAGGGTGGASCKASARGKSSDVAKSGGGGDEREKDKASPTAAAAAEAGKGINKVSSGGGSVGVGKLTPNKGSFGSLNPRGGSGRGSERGRASEEGLLSRTSSGSVPLGGGGGGGLVGGKKGAVSILLRPLLCVMPAEPGSRLMLFVAFVWSLTADADKVGYSFASSFLVFMVVQRAVMTTPLVCLCLYKSGVGKCARAVTNNIGFLLLISVMEMYVVAAFLKALDHLFVSYAIAAKRSGILLSVLGGAIFYQEKIRDRLPYILVMLAGMAIILCGTEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMD9</accession>
    <name>C1MMD9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_15637</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056913.1">
        <property type="nucleotide sequence ID" value="XM_003056867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMD9"/>
    <dbReference type="STRING" id="564608.C1MMD9"/>
    <dbReference type="GeneID" id="9682826"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15637"/>
    <dbReference type="eggNOG" id="KOG1695">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RFERENW"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="81"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="226" mass="24759" checksum="EF8C6997CA87020A" modified="2009-05-26" version="1">MKLIYFDIPGKAEAIRLCAAVGGVQLDDVRTSREKFHEMRDSGELPFGQVPALDVGDGRILAQSSAILRYVATLGGLHPTDPLEAAHVDAVAAAEEDFFAGISVSRYGARFGFEMSDEYRAQVRKALNDEVLPRHLSALQKKLEASKTGWLAGTEKPSIADFVFSPRLRWLVGGANDGIDPGLLEGYPAVTALLEKFYALPEVVKWYEQPDGEELRAEEMHSPKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MME2</accession>
    <name>C1MME2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="7">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_10598</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="7"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057389.1">
        <property type="nucleotide sequence ID" value="XM_003057343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MME2"/>
    <dbReference type="STRING" id="564608.C1MME2"/>
    <dbReference type="GeneID" id="9682828"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_10598"/>
    <dbReference type="eggNOG" id="KOG0351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTAWPER"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF155">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="5"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="230"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="424" mass="45040" checksum="96AF909EFB1E6192" modified="2009-05-26" version="1" fragment="single">QLEAMTAVMRGRDCLSLLPTGAGKSLVYVLPAMLRAERNAPGVTVVVTPLLSLLADQLRRCDEMGVDAEAWSGATDPTRLERIERDLRAAAADDEGPTLTLLFTTPESLQTPRLRAALRVASDNGHVAALAVDEAHCVSQWGHDFRPAYLALKDDRDELLGGAPIQALTATATRATEASIAAALGLRRDHVVARSSLNRANLGHEVVRRERLGDGGGDGEERAAVDHVVAVSRAAKATAPESAGIVYARERGECERVAELLATAGMDVEVFHAGRSKESLRRALANWAGGDVDAVVATVAFGMGIDKPDVRWVAHWGPPTSLEGLYQESGRAGRDGKPSRCVLYADAGELDKIRKLDPGRAEKVDAYVRGTSCRRAALLSHFDEGAGGGARACDENDVPCDACADVGAVKRMNAAADRKSDRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMI3</accession>
    <name>C1MMI3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56539</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056932.1">
        <property type="nucleotide sequence ID" value="XM_003056886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMI3"/>
    <dbReference type="STRING" id="564608.C1MMI3"/>
    <dbReference type="GeneID" id="9682371"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56539"/>
    <dbReference type="eggNOG" id="KOG2407">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NHGHYIG"/>
    <dbReference type="OrthoDB" id="331263at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007245">
        <property type="entry name" value="PIG-T"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959:SF11">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04113">
        <property type="entry name" value="Gpi16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912027" evidence="2">
        <location>
            <begin position="20"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="714" mass="76869" checksum="4D5309B73A1D0715" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMM8</accession>
    <name>C1MMM8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56590</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056955.1">
        <property type="nucleotide sequence ID" value="XM_003056909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMM8"/>
    <dbReference type="STRING" id="564608.C1MMM8"/>
    <dbReference type="GeneID" id="9682873"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56590"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GDECARY"/>
    <dbReference type="OrthoDB" id="514820at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044237">
        <property type="entry name" value="ATXR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47436">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE ATXR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47436:SF1">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="283"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="795" mass="82698" checksum="9042565632617484" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMQ8</accession>
    <name>C1MMQ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56620</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056971.1">
        <property type="nucleotide sequence ID" value="XM_003056925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMQ8"/>
    <dbReference type="STRING" id="564608.C1MMQ8"/>
    <dbReference type="GeneID" id="9682887"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56620"/>
    <dbReference type="OrthoDB" id="1699369at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82704">
        <property type="entry name" value="AlbA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="126" mass="13596" checksum="0E42B638075B319D" modified="2009-05-26" version="1">MTSSDPPVRVVLVSHDKRPLFHYVKLALDALKSDAHGDRVVVRLTGMGMACARVVTLAELLKRDGACVVTRTRTGSVKGAREGDPDRDSTKSAIEMDVTRGGAFEAKAGDVFRRRKVEASSSELPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMS0</accession>
    <name>C1MMS0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56632</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057453.1">
        <property type="nucleotide sequence ID" value="XM_003057407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMS0"/>
    <dbReference type="GeneID" id="9682417"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56632"/>
    <dbReference type="OMA" id="DAPFYAN"/>
    <dbReference type="OrthoDB" id="47172at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF6">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="371"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="542" mass="57933" checksum="35A7C4010A35A896" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN86</accession>
    <name>C1MN86_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56822</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057535.1">
        <property type="nucleotide sequence ID" value="XM_003057489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN86"/>
    <dbReference type="GeneID" id="9682501"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56822"/>
    <dbReference type="OMA" id="VIWINHA"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040039">
        <property type="entry name" value="PIGX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28650">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28650:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912036" evidence="1">
        <location>
            <begin position="27"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="419" mass="46856" checksum="685C3D41FEB25514" modified="2009-05-26" version="1">MARGATMRVLLALVLLLLTRTPPTAGAAAAADAPTAAPPARKKGMIPRWKDLPVTVKPKPLGTPREKAARHFGLRERDLFAHANASRGVLSTSSARVETLRHDLKGAGQHRKLDVDVAVSFRRKMRDGDRCHVGVVYDLDTPFYADKFELARAAILSTRRGIRQNDASLLNRTFAVFEDGYYIGERTSVQVRSIQFFFTHRSVSTFDRVTFQLTGELFLYGMALVQVNASAFAFTAPAAWRRVGSGAKVLATATFTDVQIHNRYGPVHKTKPGEWLWSAYYHAWIDHPIVVARCHGADEDGIIAGVPTVSWEDGGGDVGQTGWVVAAPPTKRETPSRLLWIIPVGVSCHKPYVIWINHAMRWLCAIIICYVVIKQPKHKIGVFATKEEKDRLNAEIRAYALKYKEEHPEVETVEWYEYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN89</accession>
    <name>C1MN89_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_32662</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Release of N-terminal proline from a peptide.</text>
            <dbReference type="EC" id="3.4.11.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexamer (dimer of homotrimers).</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057064.1">
        <property type="nucleotide sequence ID" value="XM_003057018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN89"/>
    <dbReference type="STRING" id="564608.C1MN89"/>
    <dbReference type="MEROPS" id="M17.A01"/>
    <dbReference type="GeneID" id="9682503"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32662"/>
    <dbReference type="eggNOG" id="KOG2597">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MPLWKYF"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002076">
        <property type="entry name" value="PRK00913.2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963:SF23">
        <property type="entry name" value="CYTOSOL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="LEUCINE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosol aminopeptidase" evidence="8">
        <location>
            <begin position="336"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="486" mass="50012" checksum="C1B02C43165AC78B" modified="2009-05-26" version="1">MCEADAAALTASDDVFESYGKGLAAIVHDVATAEEFKGKAGSSAFARVPAAMGLPFKLVGVVGVGKAGEIGADAWTALGAAAAAAANKAKCESLVVAKYWMGDAPEEFETKARAIAVGAYLGAFDDQRFKSEKQAKTLRLISVATPAGADVSGALTRAKATAAGVALTKQLVAAPPNVVTPTALADVARAIAAEFKDTMSVKILEKKDCEKLGMGSFLGVSEASDEPPKFIHLTYTPKGKKAKDLTNVAVVGKGLTFDSGGYNIKAGAGSMIEMMKFDMGGAGATLGAARVVAETAPPDVAAHFIVASCENMIGSRGLRPGDILTASNGKTIEVNNTDAEGRLTLADALVYAEKTAGATKIVDVATLTGAIIVGLGPEVAGVFTPDDGMASEIDAAARDAGEAFWRMPMRESYWEQMKSEIADMKNTGTRGGGSITAALFLRRFVESEDAKWAHLDIAGPVWDDKKGGATGFGAATLASWISNAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNI3</accession>
    <name>C1MNI3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55910</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057109.1">
        <property type="nucleotide sequence ID" value="XM_003057063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNI3"/>
    <dbReference type="GeneID" id="9682133"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55910"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="56" mass="6271" checksum="8FAC8A365312160A" modified="2009-05-26" version="1">MKLRPIERIGSYGARVHYLANASHWVHIDNPDGLLEILAPSFGAIDRGQGRRVNTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP23</accession>
    <name>C1MP23_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_15661</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057210.1">
        <property type="nucleotide sequence ID" value="XM_003057164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP23"/>
    <dbReference type="STRING" id="564608.C1MP23"/>
    <dbReference type="GeneID" id="9682649"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15661"/>
    <dbReference type="eggNOG" id="KOG0048">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RWHASIK"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000010">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF25">
        <property type="entry name" value="MYB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="24"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="24"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="76"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="80"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="131" mass="15642" checksum="26EEB5643306DDAA" modified="2009-05-26" version="1" fragment="single">LFSAEYFEERTDVQCLHRWQKVLNPELVKGPWTKEEDDKIIELVKALGAKQWSKIAQQLPGRIGKQCRERWYNHLNPEIKREEWSREEDQKLIVAHAEYGNRWAEIAKTFVGRTDNAIKNHWNSTLKRKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPG5</accession>
    <name>C1MPG5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA pseudouridylate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_70854</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057953.1">
        <property type="nucleotide sequence ID" value="XM_003057907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPG5"/>
    <dbReference type="GeneID" id="9683053"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70854"/>
    <dbReference type="eggNOG" id="KOG1919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WRVYAMA"/>
    <dbReference type="OrthoDB" id="428658at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF47">
        <property type="entry name" value="RNA PSEUDOURIDINE SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="3">
        <location>
            <begin position="72"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="348" mass="36892" checksum="C492AFAFBBCF4DB9" modified="2009-05-26" version="1">MPDASDASADASAAYPRPCARPGLPGDDAREIESRRAVRAKARGESLAASDVPVLRRDDADADADGDGGGAFVVVRKPAGVYVDDVLAALERDASASASASPSPSPRRLHLAHRLDRDTSGCLVVATSTRACAALTRAFADGKVRKEYLAHCSSAAASSSSEPREPDPSPSPSLDGARPLTLRTGHGRSRNGLWRVYPLSDVGRALPRDPGRKTTLVKIAETSLVVVATAAARGGGGGGERSRCAYVRATPTTGRTHQIRLHCAHAGAAIVGDVKYGGPRVVEEEEEEEEKEKETQEDDALIDTRFDGFRLHAAKIAFPHPTREGQTVEVECPPPGWWREAGESVRIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPJ6</accession>
    <name>C1MPJ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_46926</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057590.1">
        <property type="nucleotide sequence ID" value="XM_003057544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPJ6"/>
    <dbReference type="STRING" id="564608.C1MPJ6"/>
    <dbReference type="GeneID" id="9683111"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46926"/>
    <dbReference type="eggNOG" id="KOG4441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KPENPHE"/>
    <dbReference type="OrthoDB" id="498042at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056737">
        <property type="entry name" value="Beta-prop_ATRN-MKLN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632:SF24">
        <property type="entry name" value="GALACTOSE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632">
        <property type="entry name" value="LD33804P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24981">
        <property type="entry name" value="Beta-prop_ATRN-LZTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Attractin/MKLN-like beta-propeller" evidence="5">
        <location>
            <begin position="224"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="890" mass="95604" checksum="C5DF8E0B6C090C56" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPQ7</accession>
    <name>C1MPQ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tropine reductase i</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TR-1</name>
        <name evidence="2" type="ORF">MICPUCDRAFT_32788</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057994.1">
        <property type="nucleotide sequence ID" value="XM_003057948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPQ7"/>
    <dbReference type="STRING" id="564608.C1MPQ7"/>
    <dbReference type="GeneID" id="9683094"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32788"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RWINGAH"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045000">
        <property type="entry name" value="TR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42898:SF6">
        <property type="entry name" value="NADP-DEPENDENT MANNITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42898">
        <property type="entry name" value="TROPINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="282" mass="29539" checksum="AD3D8E89EF323DC4" modified="2009-05-26" version="1">MSDAEIESEPTSPWRLDGYRAVVTGSTKGIGLATAREFVALGASVLIVGRDIESVLDVVNGEFVTGAAHAFAGDISTPAGRAELVDEVAALWPDGIDILVNNAGTNVRKAALDATDEEYDRIMDLNLRATYELCRALHPALRNAPSGRPTIVNVASAAGVQSTGSGAAYAMSKAAVIQLTKTLACEWAPRVRVNAIAPWVTWTPLLENTIDADATGHQRESLRKAERATPLGRAARAEEMAAAIAFFAMPASSYVTGQTLSVDGGLLVEGFAGACVDRGEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPZ1</accession>
    <name>C1MPZ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_16211</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057669.1">
        <property type="nucleotide sequence ID" value="XM_003057623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPZ1"/>
    <dbReference type="GeneID" id="9683472"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16211"/>
    <dbReference type="eggNOG" id="ENOG502S3KV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MANRAYV"/>
    <dbReference type="OrthoDB" id="495469at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018625">
        <property type="entry name" value="Pet100"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35700">
        <property type="entry name" value="OS07G0181800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35700:SF1">
        <property type="entry name" value="OS07G0181800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09803">
        <property type="entry name" value="Pet100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="74" mass="8405" checksum="7AC3A86B5582CAA2" modified="2009-05-26" version="1">MSSARPRFSLELFKFATYLSIPIAMTVAFAANPENLETIIKRHAYVVYPPEGPKPPTNAEMKKIVEANRKKRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQT5</accession>
    <name>C1MQT5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_57405</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058184.1">
        <property type="nucleotide sequence ID" value="XM_003058138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQT5"/>
    <dbReference type="STRING" id="564608.C1MQT5"/>
    <dbReference type="GeneID" id="9683251"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57405"/>
    <dbReference type="eggNOG" id="KOG1267">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANSHRVG"/>
    <dbReference type="OrthoDB" id="261831at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15841">
        <property type="entry name" value="SNARE_Qc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="29"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="129" mass="14302" checksum="FE4B0686B17B759A" modified="2009-05-26" version="1">MSYRGAYSAEGLTSRPAASGGEVQLNMPSASDFDVDDEVEKLHGKVSMLKQMTGAIHEESGIRGKLIDQLEETMSQAGEALKVAQKEMKKAFKSGSSWHLCVLMMFCLALFLGFYVLYRMGKFIRFFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQV6</accession>
    <name>C1MQV6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_33074</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RETICULATA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058196.1">
        <property type="nucleotide sequence ID" value="XM_003058150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQV6"/>
    <dbReference type="STRING" id="564608.C1MQV6"/>
    <dbReference type="GeneID" id="9683260"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33074"/>
    <dbReference type="eggNOG" id="ENOG502QQ0I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QFKINHV"/>
    <dbReference type="OrthoDB" id="513951at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099402">
        <property type="term" value="P:plant organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021825">
        <property type="entry name" value="RETICULATA-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31038">
        <property type="entry name" value="EXPRESSED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31038:SF2">
        <property type="entry name" value="PROTEIN RETICULATA-RELATED 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11891">
        <property type="entry name" value="RETICULATA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="104"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="474"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH58147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="506" mass="53998" checksum="A03609F73FD70043" modified="2009-05-26" version="1">MAAQAALPRMTAASRVGQTRARTRQNVLASRGTPKAAPVVRFDPLGVHFRNASRVRLTKVSARSRASVRVHAESGVADRSGESTDRAQGTFNAAMQAPSMAKIGRQLGGGGAATLEKTGMDTSQQISVSSPKLADNGGGGMPPGGIKNGGGGGDGDEGDDDDYFDEGDDEGGDDSFLTTRSPIGETYERDAINAVLQEWFRTLTDVPYAIRMAIEMGIVSSMQLVRFMSVDVRPSIVRAVSRSTPSSVSRAFVGRLMADPAFLWKLGFEQVVTIGGAIAYEAAHRGDRLKEEWDLAAANVIQLSLANAMTVWCLTPTRSFGAQHKFGWQRVMDSIPNNAFDKCGPLRQYTMGMRAASVAKKATELSALGAITGGLFHGVNKALVSTRGEGFEPALPVPDLKTSMLGMGAYLGLSCNLRYQLIGGADRWMTERLTTLASAITATGLGRLANNHFGDMTRVIALGLPMHATTIKPAAKPTKKKTVKKVKKTKKKVKKSSREAREAAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQX2</accession>
    <name>C1MQX2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_33086</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 7"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058204.1">
        <property type="nucleotide sequence ID" value="XM_003058158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQX2"/>
    <dbReference type="STRING" id="564608.C1MQX2"/>
    <dbReference type="GeneID" id="9683268"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33086"/>
    <dbReference type="eggNOG" id="KOG0543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HAFGANE"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000025">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF9">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="10">
        <location>
            <begin position="52"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="10">
        <location>
            <begin position="284"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="561"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="482"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH58155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="599" mass="64482" checksum="83259E58AEADDC2A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQZ4</accession>
    <name>C1MQZ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47116</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058216.1">
        <property type="nucleotide sequence ID" value="XM_003058170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQZ4"/>
    <dbReference type="STRING" id="564608.C1MQZ4"/>
    <dbReference type="GeneID" id="9683278"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47116"/>
    <dbReference type="eggNOG" id="KOG2743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CCTLGGE"/>
    <dbReference type="OrthoDB" id="272672at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051927">
        <property type="entry name" value="Zn_Chap_cDPG_Synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603:SF1">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="323"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="591" mass="62428" checksum="BF86168F909DE905" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRM7</accession>
    <name>C1MRM7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58159</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058535.1">
        <property type="nucleotide sequence ID" value="XM_003058489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRM7"/>
    <dbReference type="GeneID" id="9684341"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58159"/>
    <dbReference type="OMA" id="VWPLCFA"/>
    <dbReference type="OrthoDB" id="497970at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="250" mass="27585" checksum="8E08944D6BFE7BF3" modified="2009-05-26" version="1">MAERRSSRRRAPEPESGTDSHNDSYDADSLESDPRERGKGRGPEGLSRLRTSAPSTSRRENVRVWPLCFAIAIEKTVRVRPAVMVASSSLLAWVTYYLQESDLELTLRAWISSPLVVFILVECLFLLCAFFVLMPHTMRQAYKDDKRTAFKVADSAVLSALPPSVARFAVGSGVAWKRAALAVARDGALFFTLYLLCVEALVGGEDEVAYIPGMKNGRTRTTGGEKDGWREMDGGYSVHSWVKSSDADGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRQ7</accession>
    <name>C1MRQ7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein TIC 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_58191</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in protein precursor import into chloroplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Tic20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058550.1">
        <property type="nucleotide sequence ID" value="XM_003058504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRQ7"/>
    <dbReference type="STRING" id="564608.C1MRQ7"/>
    <dbReference type="GeneID" id="9684356"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58191"/>
    <dbReference type="eggNOG" id="ENOG502QUSD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MMASCIA"/>
    <dbReference type="OrthoDB" id="414558at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005691">
        <property type="entry name" value="Tic20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510:SF5">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16166">
        <property type="entry name" value="TIC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1001">Plastid inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="74"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="303" mass="31841" checksum="18A57CE1FA2E258F" modified="2009-05-26" version="1">MMASCIARVGTTRALVHSPRAGVASERANGGARVTARGVAKRWADAVSIVGRGRTAVARAEGEGSKKDDTLSSLAAILGEDAEAEAAAAKAEEEKIERELAAAKKERDAALASRAANKDKPAPVVNRAAMSSMDDEDGDATAAQRGLAALSYLLPLLDGLKYSKFLLLQFPLFTLALLPLKPAIDLWFSLGFLQIIAFFALYLGVVQNQAMPKFVRFNAQQAILLDILLIVPDVLARLASGLGGDDAMLTGGPGLEAQVLMYNTVFLYVYLTSVVGAGASGLGKSVKLPIVGDAAESQINMRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS09</accession>
    <name>C1MS09_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_4777</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058601.1">
        <property type="nucleotide sequence ID" value="XM_003058555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS09"/>
    <dbReference type="STRING" id="564608.C1MS09"/>
    <dbReference type="GeneID" id="9684407"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4777"/>
    <dbReference type="eggNOG" id="KOG0033">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH57056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="109" mass="12078" checksum="FA610C2FBD90EE11" modified="2009-05-26" version="1" fragment="single">FSEATAAPMIRSMLRALAACHEHGVVHRDVKPANFLFLREADGSRRLKLSDFGLAARIKSKDATLTEVCGSYAYLSPEMARRRPYDFKVDSWAAGVVVYMLLAGEPPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS43</accession>
    <name>C1MS43_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_17282</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058982.1">
        <property type="nucleotide sequence ID" value="XM_003058936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS43"/>
    <dbReference type="STRING" id="564608.C1MS43"/>
    <dbReference type="GeneID" id="9684060"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17282"/>
    <dbReference type="eggNOG" id="KOG2667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GNFHVHL"/>
    <dbReference type="OrthoDB" id="72053at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF37">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE 5-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="112"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="486" mass="54606" checksum="605AEBA97F9BCC9F" modified="2009-05-26" version="1">MGLFSRAKLRSVDFYRKIPRDMSEGTVPGSVISIGSALLIALLLVSEIGRYATPTWKTKVVVDRSLDGDMMKINFNVSFPALSCEFASVDVGDAMGLNRYNLTKTVFKRALARDGTPLGAIEWDRDRGPNAHGRHADDDEHAGAPVHDLDPRSFEKHKKASTVLLVNYHAPWCPWCRRLEPTWEAAGIKVHSKYPKGSRNRVVLAKVDCTRHLNLCTREQVTGYPTIRVYTEGSDDVAIGNQHDHASYHGDRTLEAITEFAFHLLPDWKIEEADKTESRAVVTREEALRHESVRAVKGPGCSVTGFVLAKKVPGHVWITANSNSHSFHPEEMNMTHTVNHLFFGNQLGRNKLKALERRERGASSNWHDKLAGVTFRSLQTNVTHEHYLQTVLTTLRPAGSYVAYHAYEYTQHSHALVTTRELPRAKFHFNPSPVQVVVTEEREPFYHFITTLMAIVGGVYSVCGIADGFVHNTLNMMRKFELGKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSP8</accession>
    <name>C1MSP8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57773</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058714.1">
        <property type="nucleotide sequence ID" value="XM_003058668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSP8"/>
    <dbReference type="STRING" id="564608.C1MSP8"/>
    <dbReference type="GeneID" id="9683779"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57773"/>
    <dbReference type="eggNOG" id="ENOG502QSHD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AYVSCMC"/>
    <dbReference type="OrthoDB" id="1912023at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF20">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 10, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="268"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="367" mass="40159" checksum="50A054E53D648A89" modified="2009-05-26" version="1">MSCASCRAPRAPTASSSRRGRASPSSRSPPASRPSARRDLASTAARGEKCVRRRRDAVATDASPAGTLVLTSPEGWDVSYGTETQLSEISDVQATSFFEPSALPLLDPFLLESFRGDVSTTLGRKYEYLDSRRFAPLVTTASRDDEDESSATRRWPSNASSDERPRPVVGVVELSIQRDDDVLKFLSNAASKFSPCYGDDGDDACDAASGDDWNDGLGTNGGDMQRWADARRARMNAEEDAAAAATTATTTRAPTRSPRPGRWRGGAPADEYAYVSCMCVADAYRRRGIADALMNAAEEITLRWGYDVACLHVYQRNAGAIALYRRRGYEIVDDGCPPFDAMLGKRRFLMMKRLRGRVVGEEYQDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT02</accession>
    <name>C1MT02_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_39686</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058772.1">
        <property type="nucleotide sequence ID" value="XM_003058726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT02"/>
    <dbReference type="GeneID" id="9684211"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39686"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="216"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="526"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="342"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="539"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="599" mass="62833" checksum="872365A08E30CDDA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT66</accession>
    <name>C1MT66_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_57954</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058434.1">
        <property type="nucleotide sequence ID" value="XM_003058388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT66"/>
    <dbReference type="STRING" id="564608.C1MT66"/>
    <dbReference type="GeneID" id="9684251"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57954"/>
    <dbReference type="eggNOG" id="KOG3069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EQRWGDG"/>
    <dbReference type="OrthoDB" id="206213at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015938">
        <property type="term" value="P:coenzyme A catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="NUDIX_CoAse_Nudt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF24">
        <property type="entry name" value="PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="8">
        <location>
            <begin position="62"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="263"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="291" mass="30490" checksum="AF206177AE5911CB" modified="2009-05-26" version="1">MPPRAPSPAPAAGARSSPAAAAASSSSSRSDASTSVDDATSRLRAYWSRELARGTADAPPSARDRAAVLVPLSRAPSDGAVTALLCTRSSALSSHAGEVCLPGGKNDAFETDVEAALREAREEVGLTRDDAVVLASLPPMLSKGRVSVRPVVARVRDGFEPIPNDDEVAEVFTVRLERFLSGGDGYAYDDWEFTPGRTIRVHHFDSIKDEESGATHHVWGLTAVVLIRTAEIAFGRRAAFPLRPDGPGGTDIALLATSDGGISAFGERAGEGERGDGDDGDGTRTRTPSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTB2</accession>
    <name>C1MTB2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58005</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058456.1">
        <property type="nucleotide sequence ID" value="XM_003058410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTB2"/>
    <dbReference type="STRING" id="564608.C1MTB2"/>
    <dbReference type="GeneID" id="9684275"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58005"/>
    <dbReference type="eggNOG" id="KOG4046">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124041at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.210">
        <property type="entry name" value="Ribonuclease P/MRP, subunit p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016848">
        <property type="entry name" value="RNase_P/MRP_Rpp29-subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036980">
        <property type="entry name" value="RNase_P/MRP_Rpp29_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002730">
        <property type="entry name" value="Rpp29/RNP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01868">
        <property type="entry name" value="RNase_P-MRP_p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00538">
        <property type="entry name" value="POP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="Rof/RNase P subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="242"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="114"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="423" mass="42775" checksum="8B6391F99DC9F24A" modified="2009-05-26" version="1">MPPEDGSGKSTKKRRLDALESRFKGAARGGVAGASTASTRPGRQQHPNARPHRPHPAGGRGRGPHAPGARGFHGERASSAARGPPGGRGRGGGRRARDDAGGNRDGGLVGGFRGRRDGDGDGDDARNDPDDAWYARLGARASDGVMASAHALSTPASLRRDAASTAAMEGDGVGGNDDDVIRGEEARRAFVWQHLRDLVSTNPKSGADAEAVIASKTKDKVLLLDSATGAFSAEDVAKAKRTRGDGAAAAAGRRRALSSTQKKRAGLTSIPADKRKASMYAPLKELWVKYATGLLEGGAGGKGLGRGRDGDQKNAAAAAAAAAGVSRGALARLKAAELRGAEVRVDACARPSLAGIVGVVVRDTAKTLQLVTSRDVVVVVPKAGATFSFAAPVVVGDGGGGAAGGAGATAPRVVLRGEDLARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTI4</accession>
    <name>C1MTI4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58083</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058495.1">
        <property type="nucleotide sequence ID" value="XM_003058449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTI4"/>
    <dbReference type="STRING" id="564608.C1MTI4"/>
    <dbReference type="GeneID" id="9684308"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58083"/>
    <dbReference type="OrthoDB" id="513629at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="259"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="661"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="177"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="698"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="774" mass="81214" checksum="943A345738C11470" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTJ5</accession>
    <name>C1MTJ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58095</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058874.1">
        <property type="nucleotide sequence ID" value="XM_003058828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTJ5"/>
    <dbReference type="GeneID" id="9683940"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58095"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="134" mass="14355" checksum="2F9ED3A4BFE73427" modified="2009-05-26" version="1">MPSAHGGGDAALALVVARTQSFPNEIDGGKKRGRPKGSKSRAGSGTLNTGRKGHRRKKRAVASGGGDMYLSPAWSTPGMSHESLKLLRASGLFANDCVERAFALGDAEVRLEFERRIRAREEYASAISSNNRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTL4</accession>
    <name>C1MTL4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68197</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058881.1">
        <property type="nucleotide sequence ID" value="XM_003058835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTL4"/>
    <dbReference type="GeneID" id="9684320"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68197"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="519" mass="54566" checksum="0B98E30F0AF9488A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTQ9</accession>
    <name>C1MTQ9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_44376</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059361.1">
        <property type="nucleotide sequence ID" value="XM_003059315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTQ9"/>
    <dbReference type="STRING" id="564608.C1MTQ9"/>
    <dbReference type="GeneID" id="9684556"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44376"/>
    <dbReference type="eggNOG" id="KOG1533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ATHNYFL"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000338">
        <property type="entry name" value="GPN-loop GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="307" mass="34143" checksum="D6385062381C3F4B" modified="2009-05-26" version="1">MGFGQLVIGPPGSGKTTYCNGMAHYFSLTNRPCAVINLDPANHDPPYDADVSVEELITLDDAMREFNLGPNGAMVYCMEYLAKNLDWLRERVAPLVREGRYLLVDCPGQVELFNAHDALKTIVTELTRSRGGSDSYDLRLCVVHLVDAHLCADPTKYIAALMLSLSSMLHMETPHVNLLSKVDLMDKYGELDFNLEYYADVMDLSFLADRILRGPSGYSKLTRGLCELVEDFSLVNFLPLAIEDKTSVQRVLAIVDKSIGAATIPGPDGTTPGNGEVDERTLISHRAVGSEYERNFEVQERFFKDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU42</accession>
    <name>C1MU42_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_69455</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059130.1">
        <property type="nucleotide sequence ID" value="XM_003059084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU42"/>
    <dbReference type="GeneID" id="9684585"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69455"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="468" mass="52572" checksum="B96221434589D7C7" modified="2009-05-26" version="1" fragment="single">MYVFFRTVAHFIQNSDRVIASSRPRTRRVRTRFAVVSFSSSHLFAVAVAEIDARLSRSRSSRVVGQTEYRRAVGSTGSMFPDEGRFLLVLSDALRLLEILECREVREPAFLHAVVNLLECHPPPPILRQDRFELVIQRRHSLPTFLRIFLPARDVLRPLALQLGTVGLRQRVRLREPLVLRGLSLPAFLPAAAARVPHALKLGTVGLRQRVRLREPLVLRAGSRTSACARRAQVREVGGGLLGDRLRRLRLREILPPRGGSRTSACRSACRARAQVREVVPVFHPDSPRLLIRQELPPLLAGHLTTEVAAREQVRELLRVFVADRAVLRLLLQPPPLLAGHLTTEVAAREQVRELLRVFVADSAVLRLLLQPPPLLAGHLTTEVAAHEQVRELLRVFVADRAVLRLLLQPPPLLLRGSPSPCRARAQVREVVPVFHPDSPRLLIRQELPPLLAGHLTTEVAAREQVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU70</accession>
    <name>C1MU70_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58691</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059146.1">
        <property type="nucleotide sequence ID" value="XM_003059100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU70"/>
    <dbReference type="GeneID" id="9684586"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58691"/>
    <dbReference type="eggNOG" id="ENOG502RKAZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RELRIWY"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912070" evidence="2">
        <location>
            <begin position="21"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="131"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="382" mass="42641" checksum="B99F5A2E8ED052A0" modified="2009-05-26" version="1">MGRPPLLLLLLLLLLVVVSALSSPADAIWDRRPPECDDTCVEDDNAPSHARCAVTVLDDVVSVADADALVAAAEAHAAKHGWTRTRHANYPTTDLPWGALPGTWAVLNETWTRMEADVRARCGIKSNDVLTPNDIFLVKYDASEGGQKGLRRHRDGSTFSFNMMLSNPGDYGGGGTRVWNATDTESREGRERFWRAEVTKDPGRFPGVNLTRGDRMPRNFVPNIHMYPEDESTLHVLEKGQMLVGGGANVHQGVPVTTGTRYIVAGFVGWNRHCCSIKYCGLRGVIGFLRVWMLTGRSGMGGRADLSRELPQHDWILYREGMASLRKWCRRILFSLVAYCVVGNVAPSAHEAVKNPRRALRELRIWYRKRQKTYSCLPTRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUN8</accession>
    <name>C1MUN8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_69628</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059227.1">
        <property type="nucleotide sequence ID" value="XM_003059181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUN8"/>
    <dbReference type="STRING" id="564608.C1MUN8"/>
    <dbReference type="GeneID" id="9684970"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69628"/>
    <dbReference type="eggNOG" id="ENOG502SCTP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02134">
        <property type="entry name" value="KH-II_NusA_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058582">
        <property type="entry name" value="KH_NusA_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="TF_NusA_bacterial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="TF_NusA_KH_1st"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR NUSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648:SF0">
        <property type="entry name" value="TRANSCRIPTION TERMINATION_ANTITERMINATION PROTEIN NUSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_NusA_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26594">
        <property type="entry name" value="KH_NusA_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Transcription factor NusA first KH" evidence="7">
        <location>
            <begin position="104"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="NusA-like second KH" evidence="8">
        <location>
            <begin position="184"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="261"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="324"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="495"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF26594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="511" mass="55469" checksum="5A78EB4A50D5794D" modified="2009-05-26" version="1">MMRKLAYAFTDELSECVAATAANSYRVRTGEMVEATVVSEGRRGEYLLKLDDGAFACLPAEEGIPEKRYGQGDRVSALVLGVEDQTWAADRRAPVVVSTAIAGLLAEVLKKEVPEVATGDVVIRSVARVSGKMSKVAVSRRDGAVGTWDPVLACVGENNSRMLAIRERLGGETCQILTWSDVQEEMVAEALFPAQVVRVDKALEEADEHGGKEFAMDKYVAYVNQFDEAKAIGAGGINVKLAAALCGCFILIERYEPGNAHERRGGGEFRGDGGRGGGGWDDAEEDVDAFKMPYPDDDDDDDDDYLSDLSNLNRRTRSINLESDGLDELGWPTDRADPKTPPPREETAFSRYRTGGDVELDDLGWPDLDPPSAAPRVDPDRGRFDDLIADELIADDDEFGFDFLRDAEGALDRDAEERGVFDDDVAVPRDAADDPANWEEVGPGKVGAVMFGSNLRAGITGACTFMGDPEPTEGAGAADFLDDEFIPNETRTFGDDADEDGELGYDDEDLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUP3</accession>
    <name>C1MUP3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_58882</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059532.1">
        <property type="nucleotide sequence ID" value="XM_003059486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUP3"/>
    <dbReference type="STRING" id="564608.C1MUP3"/>
    <dbReference type="GeneID" id="9684670"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58882"/>
    <dbReference type="eggNOG" id="KOG2534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PECADME"/>
    <dbReference type="OrthoDB" id="205514at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00027">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF28">
        <property type="entry name" value="DNA POLYMERASE LAMBDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="4">
        <location>
            <begin position="12"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="701" mass="76398" checksum="F29DA27047F4D079" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUZ6</accession>
    <name>C1MUZ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58994</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059587.1">
        <property type="nucleotide sequence ID" value="XM_003059541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUZ6"/>
    <dbReference type="GeneID" id="9684718"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58994"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="300" mass="32653" checksum="1455A2AA91EE0356" modified="2009-05-26" version="1">MDGASEHAPTASTAPYARRPGEGVRTTSTIPGDGTDVEIMEVDDVAERVRAFSLRPLDDLAAMLADVEAKIPEMNDQMKAAAAAGDYEIAADIKARSTRLAEKAGIIKRAQVAAIAAKKKRARDEHESKKKRAREEREGRGDIALPAAADVAARANAVWDARIAEITEPLKSAQDTVLCIVKQGVELAAAGGSTKLRVLTGVVQEALIRALLLLTSEKARQLYSNRYPYQNGGRGYPLDEIVEEYMDQMTRMADFTGLSPVDFQISAWFREKVERCFREAPEKVVGGRAKAQKSSSSIHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVJ4</accession>
    <name>C1MVJ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_18664</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat WDR3/UTP12 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059763.1">
        <property type="nucleotide sequence ID" value="XM_003059717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVJ4"/>
    <dbReference type="STRING" id="564608.C1MVJ4"/>
    <dbReference type="GeneID" id="9685202"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18664"/>
    <dbReference type="eggNOG" id="KOG0306">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MNIPLTC"/>
    <dbReference type="OrthoDB" id="407922at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000157">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000178">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051570">
        <property type="entry name" value="TBC1_cilium_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN 3 WDR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25172">
        <property type="entry name" value="Beta-prop_WDR3_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="61"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="505"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="618"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="660"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="702"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="8">
        <location>
            <begin position="857"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="310"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="773"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="964"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="313"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="554"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="781"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="967"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="997"/>
            <end position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1023" mass="108640" checksum="D6B29AEB557876E3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVT0</accession>
    <name>C1MVT0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_2188</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060094.1">
        <property type="nucleotide sequence ID" value="XM_003060048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVT0"/>
    <dbReference type="STRING" id="564608.C1MVT0"/>
    <dbReference type="GeneID" id="9685242"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2188"/>
    <dbReference type="eggNOG" id="KOG0619">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="566279at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="340" mass="37965" checksum="B1E8BA2D018A56F8" modified="2009-05-26" version="1" fragment="single">IGFWRRFVSLTVVDLRGARMTSLPDEIQHCITLQEMRVDGNRLRAIPDVSRTAFDLRVLTAAECELSTVPEWLGACRKLHTLELGRNKITSPIVSLRECVSLRVLDISSNDVRALPELPRGLTRLLASENKIDDVSAATSCADIHTLDAERNKITSLPDDIAELHKLVVLKVAKNLLRSVDAPNMELRHTPNYAVTLDLGNRGLLHAPTIHPHFPSLTTLDLSHNSIGFLPSHVSELTALEVLRLNDNFITFLPDCSKMKNLRDLRAHSNRLMSVHASVCTLRQLETLYIGKNPLSALPDLTPCLKLKTLWMAECRFESLPLHIADCPSLTNFYAEGNPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVV0</accession>
    <name>C1MVV0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47718</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060102.1">
        <property type="nucleotide sequence ID" value="XM_003060056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVV0"/>
    <dbReference type="GeneID" id="9685254"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47718"/>
    <dbReference type="eggNOG" id="KOG1919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GVWILAK"/>
    <dbReference type="OrthoDB" id="424794at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="2">
        <location>
            <begin position="146"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="539" mass="57201" checksum="A2C963B804E5FFD8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW46</accession>
    <name>C1MW46_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Phenylalanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_18602</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="3"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059859.1">
        <property type="nucleotide sequence ID" value="XM_003059813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW46"/>
    <dbReference type="STRING" id="564608.C1MW46"/>
    <dbReference type="GeneID" id="9685592"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18602"/>
    <dbReference type="eggNOG" id="KOG2783">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PISHYPQ"/>
    <dbReference type="OrthoDB" id="4457at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00496">
        <property type="entry name" value="PheRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000083">
        <property type="entry name" value="Phenylalanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.380:FF:000003">
        <property type="entry name" value="Phenylalanine--tRNA ligase chloroplastic/mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="entry name" value="Ferrodoxin-fold anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00469">
        <property type="entry name" value="pheS_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="Anticodon-binding domain of PheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="15">
        <location>
            <begin position="67"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="16">
        <location>
            <begin position="312"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00057761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH55811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="407" mass="46394" checksum="DB06E57A4AB6B716" modified="2009-05-26" version="1">MAIPRPSPSYARPPPAPFSRRHPHLSLPRPNTTDVITGDADNNVTDHIFEKMGYALHKRPDHPLGIIKAVIGDYFDEKFGKGEFATFDDMYPIVTAHANFDSVLVPPDHVSRSANDTYYVNKDTVLRCHTSAHQAEMLKDGARKFLVTGDVYRRDSIDATHFPVFHQMEGVRVFEPKEWEDAGVDAVDLASAELKETLEGLATHLFGDVETRWVDAYFPFTEPSYELEIFFKGEWLEVLGCGVMEMKILEDAGLGDKRAWAFGLGLERLAMVLFDVPDIRLFWSDDKRFTKQFKEGMFRAGGVGMQKFKPYSKYPPCLKDVSFWLPKENPESFTENNLCEVVRDVAGSLVEEVKLIDEFENKKKGLTSNCFRITYRSMERSLTDEEINALQDKVREDMVAKLGVELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWJ0</accession>
    <name>C1MWJ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59787</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059931.1">
        <property type="nucleotide sequence ID" value="XM_003059885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWJ0"/>
    <dbReference type="GeneID" id="9685664"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59787"/>
    <dbReference type="OMA" id="MACFRAM"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="121" mass="11761" checksum="59A2384D607B61A3" modified="2009-05-26" version="1">MAGRRATMACFRAMSRVQCAPPSVARAAHGAASRAAGANRSVVAGARDSATRSFLTGGGAGAGGGAGGATAGARGAMRALAACVPSGPSGTKAQLAAARVLMHDDAMERALFGEGDDLEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXF9</accession>
    <name>C1MXF9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60144</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060685.1">
        <property type="nucleotide sequence ID" value="XM_003060639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXF9"/>
    <dbReference type="GeneID" id="9685828"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60144"/>
    <dbReference type="eggNOG" id="KOG0231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HNEIWER"/>
    <dbReference type="OrthoDB" id="270720at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084:SF263">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="370" mass="41907" checksum="54BCCE70ECB874C7" modified="2009-05-26" version="1">MPSKVPRPYHRNYTWDSIVFGDGGQFEGMVTKEGQIDKLGCFVFADGDRYDGGFRRGAMHGHGVYYWKNDGSTYFGEWDDNAQQGCGVKFYGNGAIEWGEWKDDQFLGSFTGVCGETQSYGSMNNALDVAQRARMFKYKPDSEVTMQLRAFTPYQDPVVYQEGTEWQMPGWRGELYEAPSYEDLKEQHPRLLSQMQRHNEIWERSWRYYNMDYEGEMAAREARGIDPDSLSNAEKRGDDEEDPEKLAAEARAAIELKMRQAEEEDDYDEYASADSKPKKGGKDKKGKGKKKGKGGGSAAASLTLSLRNAGTAVERAFAAASRLASRRPEIAAFAERRRARAERRRAEEAHETRRKVGPFASLSMSLPFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXT8</accession>
    <name>C1MXT8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_69204</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:18945"/>
            <dbReference type="Rhea" id="RHEA-COMP:11676"/>
            <dbReference type="Rhea" id="RHEA-COMP:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:61965"/>
            <dbReference type="EC" id="1.14.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060751.1">
        <property type="nucleotide sequence ID" value="XM_003060705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXT8"/>
    <dbReference type="STRING" id="564608.C1MXT8"/>
    <dbReference type="GeneID" id="9685891"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69204"/>
    <dbReference type="eggNOG" id="ENOG502QW74">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FWFVCDD"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF247">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="9">
        <location>
            <begin position="302"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH55520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="443" mass="47469" checksum="B70429CD3AE9E2DF" modified="2009-05-26" version="1">MCQREKKGNSAMRLLGRMEAVGLPIGPVQLRQVFFACCGAGMIAEALALMSRRDDETGARVLGKDVLVRGCGIVPGGPDGDAGMRLLEGTLRGCAGGGWEVAPVTAIDAVRVYRHPPWAPPRTEAREREEEDEEEEDEARKRMRMTAGGAAAARDVSAEADALAATLYPPGEDGEDGSFWFVCDDDGRRRPADRDALELYAPATPGTIPLDPPGLESESFRSDVPRVPGAFCVTNVFSERECAALRAAAHAIGWRRDAPDPSESGDGGLNGRLDHCELVIWPETAARIWDRIKIHAPPGAVGVNARFRFFRYGVDTIYRRHVDGSWPQAALTPEGEYVTDASEGRVRSRLTLLIYLSDGFGGGETTFYNADGCAPGTIAAAGVSPTEGGCLCFPHGDAEDSPVHEGSPVNAGLKYIIRTDVLFDKESKKADPTQGTALAEGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXZ7</accession>
    <name>C1MXZ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_69257</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the transition zone in primary cilia. Required for ciliogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TMEM237 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060478.1">
        <property type="nucleotide sequence ID" value="XM_003060432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXZ7"/>
    <dbReference type="GeneID" id="9686222"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69257"/>
    <dbReference type="OrthoDB" id="550113at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035869">
        <property type="term" value="C:ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029409">
        <property type="entry name" value="TMEM237"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28388">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28388:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15383">
        <property type="entry name" value="TMEM237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="32"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="495"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="85"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="189"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH55247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="563" mass="59056" checksum="AA1FBB02CC051DB1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYC0</accession>
    <name>C1MYC0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59854</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060256.1">
        <property type="nucleotide sequence ID" value="XM_003060210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYC0"/>
    <dbReference type="GeneID" id="9685706"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59854"/>
    <dbReference type="eggNOG" id="ENOG502QR6Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SKFIAMG"/>
    <dbReference type="OrthoDB" id="2018023at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038870">
        <property type="entry name" value="UBAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15960">
        <property type="entry name" value="LD44032P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15960:SF5">
        <property type="entry name" value="LD44032P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="166" mass="17469" checksum="DC424A41E8579AC4" modified="2009-05-26" version="1">MNPDARPCVGVRIAVPATYQLTPPVSLPPLETSADAAADAADDARFDTTRERQVLAEETSPSTSPSPSPSTSARGAPADPTSLDATVRRVLDGPEDPTIEKFLRMGYPRDAVALGVAMWGDDPTKVPEFCTFFARGIEFGFPPHVLAGALAANDNNLEAAIGCCIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYF7</accession>
    <name>C1MYF7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_40811</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060566.1">
        <property type="nucleotide sequence ID" value="XM_003060520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYF7"/>
    <dbReference type="STRING" id="564608.C1MYF7"/>
    <dbReference type="GeneID" id="9686004"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40811"/>
    <dbReference type="eggNOG" id="ENOG502QVYF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="534245at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47467">
        <property type="entry name" value="OS01G0867200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47467:SF1">
        <property type="entry name" value="WD40 REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="304" mass="32036" checksum="DE31436541EFE219" modified="2009-05-26" version="1">MAAIGDKRKRFLGAGNDAMEVTSLVRSRVALPTTRSDCGPDGDVKYPHHPSPGTIWTSSRLALQNDATASRCVAFVASAGEVFRHAVPFAGAGERVEEGKGSLLKSTTVDDGVTRVVRCVKHASEIQSLALYDPPDGGDVVLASVDAYGGGFVTTLRRGGGDDDGEWSGDAPVRQYALAPHEPAGPGTSVPGWAGAAFDRDGDGGVLAVARHFDKAVDVYENGKRARTLRTTLCPRAVSFARDPNRRGGIRTGSSADGPPLLAVAEGNHVSLWDVRAREKGGLGAFYCIHWFPYDRVGVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYH8</accession>
    <name>C1MYH8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47827</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060279.1">
        <property type="nucleotide sequence ID" value="XM_003060233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYH8"/>
    <dbReference type="STRING" id="564608.C1MYH8"/>
    <dbReference type="GeneID" id="9686007"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47827"/>
    <dbReference type="eggNOG" id="ENOG502QW6M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IAFMEAT"/>
    <dbReference type="OrthoDB" id="2019255at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34121:SF1">
        <property type="entry name" value="FILAMIN-A-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34121">
        <property type="entry name" value="MYOSIN-11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="297"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="682"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="394"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="606"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="684"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="724"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="736"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="756"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="781"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="802"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="852" mass="90382" checksum="B212F79F3FCBAD72" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYI5</accession>
    <name>C1MYI5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_59910</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060283.1">
        <property type="nucleotide sequence ID" value="XM_003060237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYI5"/>
    <dbReference type="STRING" id="564608.C1MYI5"/>
    <dbReference type="GeneID" id="9685730"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59910"/>
    <dbReference type="eggNOG" id="KOG0017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LLKVTHM"/>
    <dbReference type="OrthoDB" id="337581at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003021">
        <property type="entry name" value="Rad1_Rec1_Rad17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02144">
        <property type="entry name" value="Rad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="385" mass="40107" checksum="6A294E9A1890EB9C" modified="2009-05-26" version="1">MAKRGRSRSPRARAVHAAVMDDFVLDARVEHIRNFLNVLSVVKLSKKQHVNVSVSERGVTFVAVDDSKSLQAQANFRAEVFSRFRVNASAAGGTQGPGGTGATSFAGSFGIALGSLIDVLSVFAPMDGEAELSLRWPDRDGRLVLAAHVERGNPERPLQSCTHAAVAATERDDGGGPGGGDIVFRGETNAFTLPAHGLKEIVDDLEWPNAPMAIEMSSDPNVLTFSAAGQEIGELRVDVDARDGRGLTEFACGVNGRWLYRHAFAKAATALPGALLGPTHDRGGGDGVDAPTMTRVAIGEGGMLKVVHLVRLSRAIPHFGGGGGGGGFGGTATGGGPGSRGTPTQSATPRAPASYVVPVTFVAYPEVEMSDGEYDDFGDEVDSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYP8</accession>
    <name>C1MYP8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial carrier family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_59979</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060605.1">
        <property type="nucleotide sequence ID" value="XM_003060559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYP8"/>
    <dbReference type="STRING" id="564608.C1MYP8"/>
    <dbReference type="GeneID" id="9685751"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59979"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QQWNTGR"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="159"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="270"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="362"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="115"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="463" mass="49171" checksum="1F1E00C87D2A33FF" modified="2009-05-26" version="1">MNAPSDALFALPAETTRLPDRDPPRSVPSTHLVVHRLDREIEHARGWTLRGSVDAADDSRARAPFARLVKPATTPSSSRGGEIDGRLRSRASAFLASASLTLTGVGLVRNAPTMTARNGAVGGKTKSQKKPRQKRGGADANAERDGKRAEASASDNKNHATLKHLAVGAVSGGVSRSVVAPLERVKIEYMIDSGKVASEGGVMGSLRRIVRTEGAAGLFRGNLLNVMRIAPTKAVEFYCFDAFKKSRLRLKRDQRDGGGGAGQGNEELSLSGGERMLGGSLASMAGTALTHPVDTLRSRVTSTGMRMGEAWSGLMRNEGPMALWKGLSVNMIRVAPYGAVNFFVYDACKSAYKKTLKPGQEIGPLPTLFFGGLAGAAAQTAVYPLEMVQRRIQVSGMTSAVSAGSSAALTVKYKNVFHGIQCVYKTEGLGALYAGLVPNYAKIFPAAAVSFYVYEALKLHYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYS1</accession>
    <name>C1MYS1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_41134</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060834.1">
        <property type="nucleotide sequence ID" value="XM_003060788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYS1"/>
    <dbReference type="STRING" id="564608.C1MYS1"/>
    <dbReference type="GeneID" id="9686273"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41134"/>
    <dbReference type="eggNOG" id="KOG2295">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DMNAPPM"/>
    <dbReference type="OrthoDB" id="498148at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031053">
        <property type="term" value="P:primary miRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039727">
        <property type="entry name" value="SE/Ars2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007042">
        <property type="entry name" value="SERRATE/Ars2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021933">
        <property type="entry name" value="SERRATE/Ars2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165">
        <property type="entry name" value="ARSENITE-RESISTANCE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165:SF0">
        <property type="entry name" value="SERRATE RNA EFFECTOR MOLECULE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04959">
        <property type="entry name" value="ARS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12066">
        <property type="entry name" value="SERRATE_Ars2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SERRATE/Ars2 N-terminal" evidence="6">
        <location>
            <begin position="27"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="SERRATE/Ars2 C-terminal" evidence="5">
        <location>
            <begin position="347"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="207"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="310"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="443"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="58"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="454"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="597" mass="63735" checksum="09E7FC651596C99C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYW6</accession>
    <name>C1MYW6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60515</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061111.1">
        <property type="nucleotide sequence ID" value="XM_003061065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYW6"/>
    <dbReference type="GeneID" id="9686294"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60515"/>
    <dbReference type="OrthoDB" id="498790at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="2">
        <location>
            <begin position="301"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="431" mass="45455" checksum="3651EF580BE447E2" modified="2009-05-26" version="1">MSHLGEHHAALAALIAGKRRVALVSHPLVRSRGLDLAARCYEDFHRARRKSSCGARLRCATIVLSPALLRCDDVTHAPFGGGLVASGCLRGLKHRINDAIVDLAFAPQLNAHRKRLNLPPAKRVYHKFFLSSEVVAAFPPWFATPSAQWPEAGETAWLASGDRPVAFAVGSGNPPHARAFFRAALESLRRTRRRGIFLTRHPDALPPGVRTLDGGGGGGGGGGGGGETASHTTPFTWCTPFLKDFSRRHSSPALPFQRLTGGGGGGVGGTEAAKDDADVFYALYSRVSSSTKRSATNISSSPPIDVVHVSFADFNVLLPRCAALAHNGGVGTCAVAAKTATPQLVVPASFDQPDNARRLSVLGVAAIVPNGTFIKRSRAKHVARALEKVLDPASGIKRRCEALREKIRKGGEEVNGGGMDAAAGHVLALLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYX5</accession>
    <name>C1MYX5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41174</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060859.1">
        <property type="nucleotide sequence ID" value="XM_003060813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYX5"/>
    <dbReference type="GeneID" id="9686555"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41174"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="278" mass="31203" checksum="B4C96177A85FEC75" modified="2009-05-26" version="1">MTSLPPPRVVRVPAAAKAAEEAYHSRYVDETKTNDEKVVGDYTRGARFQFAERDENEDATPTFDDAPPKIIASDTTWRKLDERQYKSMMRKYAPAPGGGRKPAAHAALNPTRLGHDEHLPPAVPDRVDRCFKRPAWTPASRYDLDPGGTTFGKRTEAQKYKDARLAKSAYVPATVTPASNPCLITWGKGQIWGKSPKVLAAEAAVKAEKERRRKLRRQKMLDDMKPKWIPVHGAARGLIDRTPLEQLRDGPGGDQKWLMRSGKSPYADETIDQPKMRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ33</accession>
    <name>C1MZ33_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Ero1-like protein /fumarate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MICPUCDRAFT_41211</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061145.1">
        <property type="nucleotide sequence ID" value="XM_003061099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ33"/>
    <dbReference type="STRING" id="564608.C1MZ33"/>
    <dbReference type="GeneID" id="9686327"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41211"/>
    <dbReference type="eggNOG" id="KOG0537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2608">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YNGTHIW"/>
    <dbReference type="OrthoDB" id="269384at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF1">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 19" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910562" evidence="19">
        <location>
            <begin position="26"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="20">
        <location>
            <begin position="1162"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="91"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="498"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="507"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EEH54795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1236" mass="130971" checksum="8232C1CFFCFFDE89" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ98</accession>
    <name>C1MZ98_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_60654</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probably involved in the biogenesis of the COX complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SURF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061177.1">
        <property type="nucleotide sequence ID" value="XM_003061131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ98"/>
    <dbReference type="STRING" id="564608.C1MZ98"/>
    <dbReference type="GeneID" id="9686360"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60654"/>
    <dbReference type="eggNOG" id="KOG1563">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HRNYALI"/>
    <dbReference type="OrthoDB" id="10040024at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF2">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="340" mass="35140" checksum="CE09CC39D29F9DD3" modified="2009-05-26" version="1">MSRRAARVATLAVAARASASSAIGASRAAPSVGTLAPIFAPRPKISPPNRAGGIDARGFAGVAAAPRNAPTGASTSKDGGGRSWLSVAAIASPSVVCAFLCKWQLDRYELKKTAIDARDAALAAPPLTSRDLADLARRGEKPKEYAPIALEGTLETSKTVHIAPRTRSVYGSPMPGSVVLTAMRPRSPRGAPVVLVNRGWVPTDWEEPKGGTCLKTSGVTRAGETPGYFTPTNSPEKNEWHWVDLPAILRHLKLPEDTPLAQVAHDGDADRGTAAPTSYPAPVALADVRAFKVSPSDHVNYAATWGSLCVATAGLAAYALYGGRGGGANAAKKAARAIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZP9</accession>
    <name>C1MZP9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4 14">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_44656</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4 14"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061258.1">
        <property type="nucleotide sequence ID" value="XM_003061212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZP9"/>
    <dbReference type="STRING" id="564608.C1MZP9"/>
    <dbReference type="GeneID" id="9686430"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44656"/>
    <dbReference type="eggNOG" id="KOG3187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AAFMEPF"/>
    <dbReference type="OrthoDB" id="46988at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102158">
        <property type="term" value="F:very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF3">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00036671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH54908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="211" mass="23369" checksum="56745F666544C134" modified="2009-05-26" version="1">MGLTKTYLLAYNGALAFAWARVLVLASLALRDGGHRAVYDAVASPLLVAQTAAVMEILHAMTGIARSPVLVTAMQVSSRLMVVWGVLHVAPPSRVATYVIRYGFYFLKLVDALETPIGRFVNWARYTFFLALYPLGVASELWLAWSAAAYVKKRGVLSYPMPNPWNVWIDWPSVTAMFFAGYVPGFPMLFGYMLKQRKKVLSPAGKKTKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZZ1</accession>
    <name>C1MZZ1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="4">2.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_19938</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation of carbamoyl phosphate and aspartate to form carbamoyl aspartate and inorganic phosphate, the committed step in the de novo pyrimidine nucleotide biosynthesis pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="4"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061304.1">
        <property type="nucleotide sequence ID" value="XM_003061258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZZ1"/>
    <dbReference type="STRING" id="564608.C1MZZ1"/>
    <dbReference type="GeneID" id="9686743"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19938"/>
    <dbReference type="eggNOG" id="KOG0370">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VLIMHPG"/>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1370:FF:000002">
        <property type="entry name" value="Aspartate carbamoyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002032">
        <property type="entry name" value="PRK00856.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45753:SF6">
        <property type="entry name" value="ASPARTATE CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45753">
        <property type="entry name" value="ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00101">
        <property type="entry name" value="ATCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/ornithine carbamoyltransferase carbamoyl-P binding" evidence="11">
        <location>
            <begin position="13"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Aspartate/ornithine carbamoyltransferase Asp/Orn-binding" evidence="10">
        <location>
            <begin position="163"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH54954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="315" mass="34593" checksum="5EB359BC71F093F7" modified="2009-05-26" version="1">MPGACVSGLKDLKNCVEAQQFDRAMLEELFVIADAMSEVKPGSRESTMLQGFLMSTLFYEPSTRTRLSFEGAMGKLGGGILSTESAGEYSSAAKGETLEDTIRTVEGYADIVVLRHFTAGAARRAADAIESPVINAGDGPGQHPTQALLDTYTIYNELGRLDDIKVGLVGDLANGRTVRSLATMLCNFENFVFVAPEVVKMKDDIKAELDANGAKWRESEDLLGVASEVDVLYQTRIQKERFGDRLDEYEACRGVYTVDEKVMAAMKKTSIVMHPLPRLDEIAPECDADPRAAYFRQARNGLFIRMALLKVLLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N023</accession>
    <name>C1N023_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_8460</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061321.1">
        <property type="nucleotide sequence ID" value="XM_003061275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N023"/>
    <dbReference type="GeneID" id="9686491"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8460"/>
    <dbReference type="eggNOG" id="ENOG502QQ5S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AGLDYWH"/>
    <dbReference type="OrthoDB" id="5580682at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002130">
        <property type="term" value="P:wobble position ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="TrmL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="TRNA (CYTIDINE(34)-2'-O)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971:SF1">
        <property type="entry name" value="TRNA (CYTIDINE(34)-2'-O)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029256">
        <property type="entry name" value="SpoU_TrmH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="150" mass="16111" checksum="6B7740E36D40CC34" modified="2009-05-26" version="1" fragment="single">VVLVSPQIPGNTGTIARTCAASRVPLHLVGPLGFTLEDSQLKRAGLDYCVCVRVHDDWDAFYAYWSVDLGAPGRLVAKFGARPHAEEGAYLPGDWLLFGAETTGLPDEAHDACARSGGIRRIPIDEDHVRSLNLAVSAGVGVYEAIRQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0C3</accession>
    <name>C1N0C3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41511</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061609.1">
        <property type="nucleotide sequence ID" value="XM_003061563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0C3"/>
    <dbReference type="GeneID" id="9686809"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41511"/>
    <dbReference type="OMA" id="EMSSCTP"/>
    <dbReference type="OrthoDB" id="10484393at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912209" evidence="1">
        <location>
            <begin position="25"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="114" mass="11989" checksum="9CA59CC2F7CAB269" modified="2009-05-26" version="1">MASRGSSSPRFTAVLLLLFVIASAFFTIPAMAAAKAKECKSLSSCRACVTEKGCGWTAKDLKCAAKGVFAGKQVKAQSDCTPLRDSLVRLGDSLPAVSKKLVGAYDQVKSKITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2E4</accession>
    <name>C1N2E4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51498</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062072.1">
        <property type="nucleotide sequence ID" value="XM_003062026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2E4"/>
    <dbReference type="GeneID" id="9687511"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51498"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039177">
        <property type="entry name" value="SMG9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14270">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14270:SF0">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="242"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="384" mass="40036" checksum="700C7BBDD5214288" modified="2009-05-26" version="1">MASTHRVVLGGANPKRGGADARDAAAAAAAAAAAAIVAAPAFSARELRVVDDRGAWCAGERLRAHLLTDASSFVVVGVMGTKSTGKSDLAGTFVGFPSTVGVCGGEESAEGGGPGETRGVRVRGVGGNNQNQSQSRSAAASSSSSSTTPPPSVLGQPPFERDTTRAVSIRVAEDRVICVDTPPLFAGERAGRRSTSVAGAGGKTPPPPAAAAERERRVASRLARWLLRTCHVVVVMGEDDDARAAEAMVAAAREEEKEEEEDDVGGARERARIVFCQTRVPASRAMRLGTPTAPTTRAAIESLSTREEEDAAAAAVFVLPEVDDGDGVSRRRHDEVARELRRFVFASERRAFVGGVRGERGKVSEREWLGIARRAWAECVGGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2W7</accession>
    <name>C1N2W7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Set domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_68459</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062504.1">
        <property type="nucleotide sequence ID" value="XM_003062458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2W7"/>
    <dbReference type="STRING" id="564608.C1N2W7"/>
    <dbReference type="GeneID" id="9687716"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68459"/>
    <dbReference type="eggNOG" id="KOG1082">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5792673at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050973">
        <property type="entry name" value="H3K9_Histone-Lys_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223:SF3">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SET-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50867">
        <property type="entry name" value="PRE_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Pre-SET" evidence="10">
        <location>
            <begin position="237"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="9">
        <location>
            <begin position="307"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="60"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="494"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="503"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="546" mass="59856" checksum="90E74EE0FAEDDCDB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2X8</accession>
    <name>C1N2X8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51958</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062283.1">
        <property type="nucleotide sequence ID" value="XM_003062237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2X8"/>
    <dbReference type="GeneID" id="9687951"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51958"/>
    <dbReference type="OMA" id="WREWAAF"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="618"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="655" mass="68191" checksum="C3F16FD36D27C531" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3L1</accession>
    <name>C1N3L1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_52215</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062634.1">
        <property type="nucleotide sequence ID" value="XM_003062588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3L1"/>
    <dbReference type="GeneID" id="9688074"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52215"/>
    <dbReference type="eggNOG" id="ENOG502SFZF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5204190at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="194"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="128"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="314" mass="30953" checksum="48E765AE4D8C3C36" modified="2009-05-26" version="1">MAADEPARATEAPVAAAPATDDSPHEDAEGASGPDRAPDLKRGAPEADDGAPEAIGADREADAPSPKRAKTAPAEDSGAEGAAAAPPPATGEDPPAPATAEEETETRAPSSEDADAAAAEEDAPAPAPASATAASANDDPTAPAPAPAVAGSDDAPQAASGAPIGADPAEAIAAAAKAAAADALATPTPDPTHVPKTTIVPCPPSLVGRVIGKGGETIKGLQAQSGAHVQVNQDFPDGANREVIISGPGGCVDVAERMIHELLSGDRNPTTSPYVGPGQTMQILECPKDVVGKGAFYDIHWSPYDRVGVVNAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3N1</accession>
    <name>C1N3N1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">T-complex protein 1 subunit epsilon</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">CCT-epsilon</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_49719</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062403.1">
        <property type="nucleotide sequence ID" value="XM_003062357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3N1"/>
    <dbReference type="STRING" id="564608.C1N3N1"/>
    <dbReference type="GeneID" id="9688084"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49719"/>
    <dbReference type="eggNOG" id="KOG0357">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SHPQMPH"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03339">
        <property type="entry name" value="TCP1_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000053">
        <property type="entry name" value="T-complex protein 1 subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000003">
        <property type="entry name" value="T-complex protein 1 subunit epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000049">
        <property type="entry name" value="T-complex protein 1 subunitTheta, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012718">
        <property type="entry name" value="Chap_CCT_epsi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02343">
        <property type="entry name" value="chap_CCT_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH53222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="536" mass="58513" checksum="F36AD232C205C1DD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4H1</accession>
    <name>C1N4H1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52554</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062997.1">
        <property type="nucleotide sequence ID" value="XM_003062951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4H1"/>
    <dbReference type="GeneID" id="9688230"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52554"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="232" mass="25776" checksum="F69DE1C8502277D8" modified="2009-05-26" version="1">MTQEDVPEAAADPVAADLEEILGALDASLSRRPPRVPDAPAPDPGVTAELEAMLTELEKKEDAARALPAEEEAELYDYQDEPDESISNAEIAEALSKTTRRHRNRRLTSEGVRRTLRNGRTLCQKLALDGVWRDDVGGALRPDVLGRAGMLRASFGSVNGFRAWIRRLGEGTRETSAMLYDASPMEMEWWVRCGTTEEEKLPAGVAEMSDERLRDVGAVDEAERDRRRNPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4K4</accession>
    <name>C1N4K4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42435</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062805.1">
        <property type="nucleotide sequence ID" value="XM_003062759.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9688245"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42435"/>
    <dbReference type="OMA" id="KWTMWTM"/>
    <dbReference type="OrthoDB" id="10684785at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="entry name" value="PGBD-like superfamily/PGBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF66">
        <property type="entry name" value="CARD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="PGBD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="946"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1356"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1587"/>
            <end position="1942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2013"/>
            <end position="2067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="806"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="986"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1104"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1118"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1164"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1223"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1305"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1317"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1376"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1466"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1502"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1513"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1612"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1702"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1717"/>
            <end position="1733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1742"/>
            <end position="1759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1760"/>
            <end position="1770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1833"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1872"/>
            <end position="1884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1885"/>
            <end position="1908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1921"/>
            <end position="1942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2017"/>
            <end position="2031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="2043"/>
            <end position="2054"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2265" mass="242699" checksum="A114056D293A9E63" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4Y3</accession>
    <name>C1N4Y3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_21894</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063074.1">
        <property type="nucleotide sequence ID" value="XM_003063028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4Y3"/>
    <dbReference type="STRING" id="564608.C1N4Y3"/>
    <dbReference type="GeneID" id="9688315"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21894"/>
    <dbReference type="eggNOG" id="KOG1487">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SAKHPGQ"/>
    <dbReference type="OrthoDB" id="603at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019003">
        <property type="term" value="F:GDP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17230">
        <property type="entry name" value="TGS_DRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000003">
        <property type="entry name" value="Developmentally-regulated GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000740">
        <property type="entry name" value="Putative GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="64"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="291"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="369" mass="41354" checksum="1B4CD160520196BE" modified="2009-05-26" version="1">MSDIMEKIASIELEMSRTQKNKATAAHLGSLKAKLAKLRRDLIEPSSKGGPKGEGFDVTKTGDCRVGLVGFPSVGKSTLLNKLTGTFSEVAAYEFTTLTCIPGVIRYRGAKIQLLDLPGIIEGAKDGKGRGRQVISTARTCNVIVIVLDALKPLTHKRLIEHELEGFGIRLNREPPKITFRKKDKGGISFTPNNNGETTFLDEETVKNILSEYKIQHADVKLHEDSTDEELIDVIEGSRIYVPCIYAINKIDQITVEELDLLTKMKHYVPVSAHKEWNLDGLLETVWDYLDLVRVYTKPRGVNPDYDDPVVLPRKACSVEDFCNRLHKGIMRSFKQALVWGLSVKHRPQKVGKEHILEDEDVVQIVKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N505</accession>
    <name>C1N505_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="2">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_36172</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>9-ribosyl-trans-zeatin 5'-phosphate + H2O = trans-zeatin + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:48564"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16522"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:87947"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O = N(6)-dimethylallyladenine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:48560"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17660"/>
            <dbReference type="ChEBI" id="CHEBI:57526"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="2"/>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063086.1">
        <property type="nucleotide sequence ID" value="XM_003063040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N505"/>
    <dbReference type="STRING" id="564608.C1N505"/>
    <dbReference type="GeneID" id="9688325"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36172"/>
    <dbReference type="OrthoDB" id="414463at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223:SF70">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="86" mass="9379" checksum="3F8F7D2EA7331993" modified="2009-05-26" version="1">MITWQQLGYHAKPVGVLNVAGYFDLFLKFLDESTARGFIRREARAIVVVGDTPAELLDKLETYAPPRSLIESLAKENGGGGGDAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N527</accession>
    <name>C1N527_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_22165</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062899.1">
        <property type="nucleotide sequence ID" value="XM_003062853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N527"/>
    <dbReference type="STRING" id="564608.C1N527"/>
    <dbReference type="GeneID" id="9688339"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22165"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LYWSALM"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF53">
        <property type="entry name" value="PROTEIN ACTIVITY OF BC1 COMPLEX KINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="256"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="689" mass="75222" checksum="D110277DD90F3CCE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1N545</accession>
    <name>C1N545_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_66924</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063101.1">
        <property type="nucleotide sequence ID" value="XM_003063055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N545"/>
    <dbReference type="STRING" id="564608.C1N545"/>
    <dbReference type="GeneID" id="9688350"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66924"/>
    <dbReference type="OrthoDB" id="10646177at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF33">
        <property type="entry name" value="HELP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="391"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="527" mass="53700" checksum="9AD9D32BC136F0D8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N568</accession>
    <name>C1N568_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52820</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063114.1">
        <property type="nucleotide sequence ID" value="XM_003063068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N568"/>
    <dbReference type="STRING" id="564608.C1N568"/>
    <dbReference type="GeneID" id="9688360"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52820"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="2">
        <location>
            <begin position="98"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="438" mass="48660" checksum="3404C06C53458DF5" modified="2009-05-26" version="1">MKDEDGDEEEDEDEEAAAASELARHFLENFGPTSHCSFRALRYPGAADAEARSTHWSPYDRVGVVASIARGMGTDDDGAKKTKKRRRISSDEYRSITPVGIAEHTDFEAFTLLHQTRPGLELKDLAGTWRDASCAPESSTFTVIIADVMERWTGGLLTATPHRVAFTPHERLSLVRFNGLDPGTVVETLPAFRGRPSPTHRAATTTQGEHVGRMVTAAAKNLEDMLETYPKRALTTNPRRFAQLIVLLGKHASGEFEGRWTGFIEEVKPRETPARAALRAVARGNLRWNLRWAAAAGLTRDAVMEALESNTHERARLRFRGWHDGLVIEHEFTLDLDGADGASLIPEDDDDDESDESDAPARMRPRWFDEGEIPYDEMPEDDRHWYPRALALARECGGGNAAAGTKPGWRELIVGEFRFGGDDARLVSKTLERIATDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5Q3</accession>
    <name>C1N5Q3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48801</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063401.1">
        <property type="nucleotide sequence ID" value="XM_003063355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5Q3"/>
    <dbReference type="STRING" id="564608.C1N5Q3"/>
    <dbReference type="GeneID" id="9688640"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48801"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QFHFRIT"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000006">
        <property type="entry name" value="DnaJ subfamily B member 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chaperone DnaJ C-terminal" evidence="2">
        <location>
            <begin position="11"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="188" mass="21052" checksum="C3A9FDB3A2260363" modified="2009-05-26" version="1">MPGGRKKADPIEQSLRLTLEEMYYGCSKNLKLTRTVMRGDVEQRVSETLTIDVKPGWKKGTKITFPEKGDEAPGVIAADIVFVIDEKRHPQFERDGNDLVKTVKVDLSEALLGANVFVTTLDGKSINVEVKEVIDPKYVKVLIGEGMPLSKSPNSRGDLKIKFEVAFPKTLDDDRRKKLREALDGCEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5Y1</accession>
    <name>C1N5Y1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53088</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063236.1">
        <property type="nucleotide sequence ID" value="XM_003063190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5Y1"/>
    <dbReference type="GeneID" id="9688882"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53088"/>
    <dbReference type="OMA" id="APWAYPG"/>
    <dbReference type="OrthoDB" id="513676at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010865">
        <property type="entry name" value="DUF1499"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801:SF6">
        <property type="entry name" value="SLL1620 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07386">
        <property type="entry name" value="DUF1499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912400" evidence="2">
        <location>
            <begin position="21"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="359" mass="37607" checksum="F8AB8A9DBE9BF2BD" modified="2009-05-26" version="1">MTAALAAAAAAIAAPRRALASSPPPPPSEGDCADCVGVVDGLLNSCPGETEACVSSQNDDEAHFVAPWAYPGDRVAAMRRLVDVVAGVAPRGQLAESDRARLEAASDDDDGGGWTLTPAGEFTLNAPPPPRAEIGRGRSNARSAALASRVLAAGSFASAGRNDAGRNANDAPPRRVTTAVAAYDEAAGYVRLVVVDGERSSESVGAVGAVGAVGADVYDVEFLFLEDDEVCDVRAAARDAPRGGAWSLSYVDGVKARSISTLTGPRATASFARWTPFLEDLDFFGPPTFRSFLSAHPAYTRGGARALLEGLRIGVGWEILPVISAFDPRFNNSKRLWFERALTPMFDPSVMDTRRDGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N655</accession>
    <name>C1N655_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53161</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063277.1">
        <property type="nucleotide sequence ID" value="XM_003063231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N655"/>
    <dbReference type="GeneID" id="9688915"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53161"/>
    <dbReference type="OMA" id="WKECAPR"/>
    <dbReference type="OrthoDB" id="10547318at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="394" mass="43176" checksum="AE238B399B529061" modified="2009-05-26" version="1">MDTARERLSHACLLVSKATGHLEAACAEHEAAQGTVKRWVKAATATATASGSDDRDDAAFDPVGQRARDLRRMNLGRKDAPAPAAGSEETPGKSVASASASARALPAEFVALRNKYVDAATTHTSSGLLDIRDSIRASSTPFMAKLSARRGRGRKKSTRRATRADGEECDARVDDLVAARATLAATRWIERALEGVNWRAMKRESSDDAHELCDVAYTIGCVVRLWKECAPRVERLSKLPDARAATRRDAFLLALCASKKLSYPDRSEYAALETTAMREVTRSMESDGSFLTWLPEQCWQGGVPPPPPDVSLKSPKEAYVEVASAWQRIQSNLFMAQLESSLYHDLIPDIFVNAFESGEMREDELAWKLRAVRSIVMAGKRDRCATIGVYEDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6D5</accession>
    <name>C1N6D5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53247</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063514.1">
        <property type="nucleotide sequence ID" value="XM_003063468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6D5"/>
    <dbReference type="GeneID" id="9688953"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53247"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF137">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="470" mass="51277" checksum="051DA582C5B288A5" modified="2009-05-26" version="1">MALVLLRERSLGDDSAWAPYIAQLPAGYDLLGCWTDDQLEELQCERLQDAARAQRAENNAAFDAVRMNVSAYDSDYDLGLGALTKEDVVWGLNTVRSRSYRAKYPSSCGVLPPLSNLEGKTLDAAALLTKSARQRSGEKSESANKESVFMLPFLDALNHRDNKGSGGATKLVFMSPLEDDAAERGAKGTFELRSPAAVEKDAEAVVCYGDKNNEELLLRYGFCVENGVHDEITLPGCMDELEWVMPGSARESDLKAERLDEAVKRARLNDEGKASVNLLWALRVLLASDATYEAAGGAKGLMRASLPGEDGGEAADAAEDGERPGEVDATEAQLAAEASLALACEQELAKMGGRDALAEDEINYEAASKVSAQIEIECAEDAEACGTPEEAEYLRRVLDFLSRRFSPPIPRWFQSRHASTPFNSASDAFQLHPDVALNDGTTLRRLLIALRFRVTRKRVLAMALDRYTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6F7</accession>
    <name>C1N6F7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_53269</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063331.1">
        <property type="nucleotide sequence ID" value="XM_003063285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6F7"/>
    <dbReference type="STRING" id="564608.C1N6F7"/>
    <dbReference type="GeneID" id="9688963"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53269"/>
    <dbReference type="OMA" id="MGFLTRW"/>
    <dbReference type="OrthoDB" id="496273at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035204">
        <property type="entry name" value="NDUFB11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37709">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37709:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17250">
        <property type="entry name" value="NDUFB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="99" mass="11737" checksum="A9BDD317D3C95EF1" modified="2009-05-26" version="1">MNKRTLPSALVARQSRRRIARSMGFLTRWIASKMEDPAEREEKWVKHMRETDAKCDELKKRWNQPTKTHGYWAKDKMQTTFKFSLDPILTNAPGKTQGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1N761</accession>
    <name>C1N761_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">EngB-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_53567</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063845.1">
        <property type="nucleotide sequence ID" value="XM_003063799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N761"/>
    <dbReference type="STRING" id="564608.C1N761"/>
    <dbReference type="GeneID" id="9689119"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53567"/>
    <dbReference type="eggNOG" id="KOG2486">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="INHFEMI"/>
    <dbReference type="OrthoDB" id="391988at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649:SF13">
        <property type="entry name" value="ENGB-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649">
        <property type="entry name" value="MSS1/TRME-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0717">Septation</keyword>
    <feature type="domain" description="EngB-type G" evidence="11">
        <location>
            <begin position="333"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="68"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH52218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="526" mass="56520" checksum="792174CE40EF0EB1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7U6</accession>
    <name>C1N7U6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53833</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063971.1">
        <property type="nucleotide sequence ID" value="XM_003063925.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N7U6"/>
    <dbReference type="GeneID" id="9689594"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53833"/>
    <dbReference type="OMA" id="HQVHVEA"/>
    <dbReference type="OrthoDB" id="10494017at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="695"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="979"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1137"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="160"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="388"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="695"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="735"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="756"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1137"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1183"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1219"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1261"/>
            <end position="1270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1293" mass="139662" checksum="762AD77F7C2C444D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N896</accession>
    <name>C1N896_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54003</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064230.1">
        <property type="nucleotide sequence ID" value="XM_003064184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N896"/>
    <dbReference type="STRING" id="564608.C1N896"/>
    <dbReference type="GeneID" id="9689671"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54003"/>
    <dbReference type="eggNOG" id="KOG2497">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="545599at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038899">
        <property type="entry name" value="METTL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23108:SF0">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23108">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="420" mass="45057" checksum="5C8F8B5B5EB49CCB" modified="2009-05-26" version="1">MAAPAAGAPNADADEKFLSEVHVGRGDGGGGISRFEFFAAPWRRDDDDDDASDDDDDDGDLVVKRKRRRRGSAVTIRHDVDTSLRDVGMQVWRGALLACDWLAHVAAGEERRAATTTTTTTTTTTTDPRNAMRGAVVLDLGAGTGLTGIVAARCGARRVFLTDVGDGVLANCARNAREDGACVVRELDWMDDDDDDDDGGGGGGGGGTSLAAWPPEDVDTLDECRLIVCADCVYDDALTDALFRTLRRLLRRLNAAATAAAAEGEVLKERRSPRERGRMGTSHDEKRRAPREGERSPGNGRDHATISSAAASRPRVIFAGERRVNFAVGDAAPRAHAHERFLSHLGLAPDAASFAAAADVPEASRRTSDAVSDNVSDAVSDRRTSASAFRARRIDPFDVPQRVMYERGGELELWEVTLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8F1</accession>
    <name>C1N8F1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_23075</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064257.1">
        <property type="nucleotide sequence ID" value="XM_003064211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8F1"/>
    <dbReference type="STRING" id="564608.C1N8F1"/>
    <dbReference type="GeneID" id="9689698"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23075"/>
    <dbReference type="eggNOG" id="KOG0589">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SEQMNAH"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08215">
        <property type="entry name" value="STKc_Nek"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF7">
        <property type="entry name" value="NIMA-RELATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="4"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH51879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="266" mass="30353" checksum="7B86B1ECFD875788" modified="2009-05-26" version="1" fragment="single">MQSYDLKEQIGRGSFGTCHLAWHRAERRMYVAKRIPVHQMAEREEALREAQLLSALRHPNIIAYKESFIEDADKTLVIVTAYAEEGDLFTHIKRARESGRRFRRRQLLDWVTQIALALDHIHALRVMHRDLKTQNIFLGRGGVVKLGDFGISKVLERTDDFATTVTGTPYYLAPEVCTNQPYTLKSDVWSLGCVAYEIATLRHAFAADSLLSLVFQIVNGTCPPIPTERGYDHRFAGLVSVMLERDARARPTASELLRHPLMQEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N954</accession>
    <name>C1N954_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-phosphatidylinositol-4-phosphate 5-kinase</fullName>
            <ecNumber evidence="1">2.7.1.68</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_43480</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.68" evidence="1"/>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064394.1">
        <property type="nucleotide sequence ID" value="XM_003064348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N954"/>
    <dbReference type="STRING" id="564608.C1N954"/>
    <dbReference type="GeneID" id="9689835"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43480"/>
    <dbReference type="OrthoDB" id="20783at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="4">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="18"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="204" mass="21833" checksum="797B9CCC5295EA5A" modified="2009-05-26" version="1">MRANKLIDYSMMLGLHTRRREGEEAVAEGDSPGRGPGYGLKPGPGPRASVSDDDAAATTAPGAPPSSPEGGDAPDDQSSTPPGPNTAARLETYRRRVDGKVGPFSASVEEDETAMFQLRALETPDGLAYLGIIDILTQYGGAKAIENFCCGVVAGCGADISCQPPRKYARRFLRLINKMLKPPEKDGAEWEERGDGAVRKLEWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N991</accession>
    <name>C1N991_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54412</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064410.1">
        <property type="nucleotide sequence ID" value="XM_003064364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N991"/>
    <dbReference type="GeneID" id="9689851"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54412"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="180" mass="19110" checksum="45D34F50EE6F54C6" modified="2009-05-26" version="1">MDNYPQLTSSTFTRCRFVVAASEHAYRDGAAHQKSAKDAHRGSVYDSGVFILQSEKAAASDVGKRVAAEGGKRTENEIRRAMAAGKERADAAAAARAASERVRAGEAAAKEKEKEGGGGAAKKRKAKSDEEEDEEGDDGDGKKKKTAGGKKKESKAAKKRRKRREAKALEPPPPATLAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9W6</accession>
    <name>C1N9W6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_43640</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064805.1">
        <property type="nucleotide sequence ID" value="XM_003064759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9W6"/>
    <dbReference type="STRING" id="564608.C1N9W6"/>
    <dbReference type="GeneID" id="9690128"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43640"/>
    <dbReference type="eggNOG" id="ENOG502QQTD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KDMKRGH"/>
    <dbReference type="OrthoDB" id="1914410at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053284">
        <property type="entry name" value="RGS1-HXK1_interactor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34554">
        <property type="entry name" value="RGS1-HXK1-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34554:SF2">
        <property type="entry name" value="RGS1-HXK1-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="241" mass="25295" checksum="526AFF004F04D7F5" modified="2009-05-26" version="1">MELPPPVRDVLDAVAGALPGAATASNVVDSAVSSIVRIGSTRVAVATEVASAQIAVARSRLDAVETAAREIESRFFERPTAIATSAVTRAPYATAAGAVAVASLALPGTRALLWRATFGRLQSEEFLFNRATRAYESLAHAAEGRAGELAKAREAAAIAEEEMSRGRSKLRAAAKELKRLGAANARDESKANLVLDELRSLPSKHALSLRAKVADASAELRKIRGGVDDGLRKAFRAGVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Y7</accession>
    <name>C1N9Y7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54691</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064816.1">
        <property type="nucleotide sequence ID" value="XM_003064770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Y7"/>
    <dbReference type="STRING" id="564608.C1N9Y7"/>
    <dbReference type="GeneID" id="9690257"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54691"/>
    <dbReference type="OrthoDB" id="188741at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037386">
        <property type="entry name" value="CCDC40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275:SF8">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="137" mass="15220" checksum="4E577E356C9F081B" modified="2009-05-26" version="1">MSTPRGGTPSGGGSSSNDARTDDDDDDDDDALAGLPPDHPLLERAQRALRAQLLDSKRELEEKIKEKGDELNKEKRRREQIGVELYTTQQQLAKLQTNLDKTHDAHAALEATREQSEARSFLHRSPYDRVGVVDAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA59</accession>
    <name>C1NA59_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_4062</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERGIC family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064734.1">
        <property type="nucleotide sequence ID" value="XM_003064688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA59"/>
    <dbReference type="STRING" id="564608.C1NA59"/>
    <dbReference type="GeneID" id="9690292"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4062"/>
    <dbReference type="eggNOG" id="KOG2667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ISGERHY"/>
    <dbReference type="OrthoDB" id="270930at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF25">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="8">
        <location>
            <begin position="5"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="7">
        <location>
            <begin position="187"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="363" mass="40165" checksum="A0B0F98DBB9838ED" modified="2009-05-26" version="1" fragment="single">VAKTLRRMDVYSSSKVIEDFRQSSSMSGGIITCACALLCFVLFVNEYFYHRTPVVKSSLTVDATGLDAKTSANSNRLHVEIDITFHQLPCDIINMDTMDQAGEAFHDVHSGHLKKRRLDSDGKPLEGVFKHEKANAHKEIREDIESHALALSGDEEYKTSEEDLMPEEGLTMFNLKQLLDKQFPGGIEKAFKNEAREGCEVIGYLEVNRVPGSFSVSPGKSIRLGMEHVQLNVQSRLNMSHTINRFAFGKSFPGFVSPLDGNARDLDPNYVHQYFLKIVPTSFTPLRGEYLQSNQYSVTEASAPAKALNVVGSKPSGVYFNYDLSPLRVDYVESRNSMTEFITSVCAIVGGVASMSGLVQAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGW6</accession>
    <name>C1MGW6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sam-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_49964</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055391.1">
        <property type="nucleotide sequence ID" value="XM_003055345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGW6"/>
    <dbReference type="STRING" id="564608.C1MGW6"/>
    <dbReference type="GeneID" id="9680570"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49964"/>
    <dbReference type="eggNOG" id="KOG2912">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="514248at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010286">
        <property type="entry name" value="METTL16/RlmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393:SF0">
        <property type="entry name" value="RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05971">
        <property type="entry name" value="Methyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="39"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="563" mass="60199" checksum="BF4AE5ED3A47B983" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGX1</accession>
    <name>C1MGX1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Prasinophyte-specific protein-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PSP4</name>
        <name evidence="1" type="ORF">MICPUCDRAFT_70671</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054850.1">
        <property type="nucleotide sequence ID" value="XM_003054804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGX1"/>
    <dbReference type="GeneID" id="9680777"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70671"/>
    <dbReference type="eggNOG" id="ENOG502SFT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35315at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="Tautomerase/MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="72" mass="7800" checksum="11BDF829D9B3BA10" modified="2009-05-26" version="1">MPFVHVAWLPKACRTPEIRKEVASAIIKAVTAVKGAEITPDKVVVRFSEAVDGFALPPGHTHENVDQPVAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH73</accession>
    <name>C1MH73_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_30735</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055444.1">
        <property type="nucleotide sequence ID" value="XM_003055398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH73"/>
    <dbReference type="STRING" id="564608.C1MH73"/>
    <dbReference type="GeneID" id="9680456"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30735"/>
    <dbReference type="eggNOG" id="KOG0668">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DYNKNQP"/>
    <dbReference type="OrthoDB" id="10254671at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000059">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000088">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="48"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH60696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="354" mass="40887" checksum="54CF61C6A237756A" modified="2009-05-26" version="1">MAQRIGKAIRRDAVVSKARVYCDVNVQRPREYWDYEALTVNWGEQSDYEVVRKVGRGKYSEVFEGVHAGNNSKCVIKILKPVKKKKIKREIKILQNLTGGPNIIKLLDIVREPQSKTPSLIFEHVNNTDFKVLYPTLTDYDVRYYILELLKALDFCHSQGIMHRDVKPHNVMIDHEKRQLRLIDWGLAEFYHPAKEYNVRVASRYFKGPELLVDLQDYDYALDMWSLGCMFAGMIFRKEPFFNGHDNYDQLVRIAKVLGTDELYAYLAKYRIELDPHLESLIGRHSRKPWSKFVNADNQHLVSSEAIDFLDKLLRYDHQERLTSKEAQDEPYFNPVKQAAAAAEGGGASGGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHF0</accession>
    <name>C1MHF0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46218</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055479.1">
        <property type="nucleotide sequence ID" value="XM_003055433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHF0"/>
    <dbReference type="GeneID" id="9680326"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46218"/>
    <dbReference type="OrthoDB" id="10674931at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="331"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="641"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="404"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="524"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="641"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="674" mass="76015" checksum="B716C9EF07592604" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHQ3</accession>
    <name>C1MHQ3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_46257</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055533.1">
        <property type="nucleotide sequence ID" value="XM_003055487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHQ3"/>
    <dbReference type="STRING" id="564608.C1MHQ3"/>
    <dbReference type="GeneID" id="9680914"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46257"/>
    <dbReference type="eggNOG" id="KOG4275">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CMSARVQ"/>
    <dbReference type="OrthoDB" id="5855668at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051728">
        <property type="entry name" value="RING-FYVE_E3_ubiquitin-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14879">
        <property type="entry name" value="CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14879:SF5">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910462" evidence="5">
        <location>
            <begin position="21"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="255"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="452"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="344"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="355"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="500" mass="51814" checksum="F759697C8C3C5F51" modified="2009-05-26" version="1">MTRALLAALVATLLVREVAASRPVPVAAPAPTDTVLSLCDCAFEEYGGNLNEPQDGLACKRDGFFVAGFETPGQYAQTHGSFIPLSRAICCRPCLAPGTTSLPGVGNVSAFESVIASNCQASKRAGKSSDSSIKGLSCPADSFLQGFLHDVRANPQSPSQYYYPFDLGQCCSPRVLLANGAELPVERCQCTRNSAAYAVGCGAANTPDSAAASGGLIFAFENSLAAASPSGEPVDVPVSPVRCCKACISPNAKPSMDDCSALDFCRGNGDCTADGHCVCRDGWGGVDCGDVDGDARALRATMVNAALVACALVFGCLVGTGRFVRCLGLARDRRPTALEELLIQGESGEERDGNEFDFEADDLSTSDESERDGGGDDDDDDGDDDDDGDDDDDGDGGGAGDGGDGAVEEGDASEPATESDATKPSGAGDERKGAAIDAHGGADPRSQDAMECTVCMSARVQTVLIPCGHACLCRKCARRIRRCPCCRTVVERRQKLYLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHS0</accession>
    <name>C1MHS0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_50300</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055541.1">
        <property type="nucleotide sequence ID" value="XM_003055495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHS0"/>
    <dbReference type="GeneID" id="9680250"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50300"/>
    <dbReference type="eggNOG" id="KOG1971">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WQLLEMS"/>
    <dbReference type="OrthoDB" id="498233at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042799">
        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045814">
        <property type="term" value="P:negative regulation of gene expression, epigenetic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46402:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-TRIMETHYLTRANSFERASE SMYD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46402">
        <property type="entry name" value="SET AND MYND DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="12">
        <location>
            <begin position="23"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="13">
        <location>
            <begin position="808"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="395"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="404"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="426"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH60793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="896" mass="93175" checksum="93C90A6984FB20BA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHT8</accession>
    <name>C1MHT8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50317</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055013.1">
        <property type="nucleotide sequence ID" value="XM_003054967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHT8"/>
    <dbReference type="GeneID" id="9680282"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50317"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="1">
        <location>
            <begin position="17"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="61" mass="5849" checksum="1E2F6CD2897AA350" modified="2009-05-26" version="1">MEVAPAAMTSVAAAAVAADAGGGADDATTLVEMGFAREDARRALDAAGGDVAAAVDILSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHV6</accession>
    <name>C1MHV6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_61451</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055022.1">
        <property type="nucleotide sequence ID" value="XM_003054976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHV6"/>
    <dbReference type="STRING" id="564608.C1MHV6"/>
    <dbReference type="GeneID" id="9681125"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61451"/>
    <dbReference type="eggNOG" id="ENOG502QTR3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RACKDEY"/>
    <dbReference type="OrthoDB" id="498177at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053305">
        <property type="entry name" value="Folate-binding_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018143">
        <property type="entry name" value="Folate_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37390:SF1">
        <property type="entry name" value="FOLATE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37390">
        <property type="entry name" value="OS02G0592500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03024">
        <property type="entry name" value="Folate_rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910251" evidence="4">
        <location>
            <begin position="33"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Folate receptor-like" evidence="5">
        <location>
            <begin position="58"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="215"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="327" mass="33648" checksum="137BAD04EF0A9872" modified="2009-05-26" version="1">MTTTIASSTRAIARVLLVATCFVALATTDAAAAPTPTPTPRTCVSHDGLPEFAIAGKPPAKNRGLTFCADYGKSTCCDKGTTDAIRRVVAHMQANSFSPRCRDAWTSLECSVCDPRAGTTPRTAVCAHACDAIYRACKDEYFSEDSLRRLVPCRASDTICTKLSDWGGDGGGGDGEDDGTGTNGDEWGGEAMCRAAGYDPVRAGVVRAQPGGWCFEPPAPDAHRSGPGSGSGSSKSDGGGGASGSKKAGKGAKKRGGKAADAEDYAAGTPAWMTKAYVLIAVAAALYVGLRAARRGGSAGASLRARHNARMAAESRAGRARNVDKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHW9</accession>
    <name>C1MHW9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_43822</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23352"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="2.6.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055028.1">
        <property type="nucleotide sequence ID" value="XM_003054982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHW9"/>
    <dbReference type="STRING" id="564608.C1MHW9"/>
    <dbReference type="GeneID" id="9680873"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43822"/>
    <dbReference type="eggNOG" id="KOG1405">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GLMCAFD"/>
    <dbReference type="OrthoDB" id="496381at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034386">
        <property type="term" value="F:4-aminobutyrate:2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000073">
        <property type="entry name" value="Probable 4-aminobutyrate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206:SF1">
        <property type="entry name" value="4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="458" mass="49818" checksum="3079AE4749692CA1" modified="2009-05-26" version="1">MRTTCPGPNTLAARAELDAFQETGALRFVVDVENSRGCYVRDVDGNVMLDMFSHIASLPIGYNHPTMLEVFTNPRNVATLAHRPALFNLPPAGYAKTVRETLMSGAGLTHVTTQMCGSCANENAMKQVYIAVANRRRRERGGYGAGDVSEEELSSCMVNRAPGSKPYKFLSFHGAFHGRTAACLSLTHSKPTHKLDIPAFEWPIAPFPRLRYPLDDPACAAHNAAEEARCVKETCELLDADPDVVGVIVEPVQSEGGDNHASGAFFRSLRAECASRGVKFIVDEVQTGCGASGTFWAHEQWGLDDPPDAVTFSKKMQIAGYYTKADLVPDAPYRVFNTWMGDPGKVLMLEAVLKCVKNDGLVENARVTGEYLREGLHALSRAHAGKLHNVRGVGTITAVDLDSSAARDDAVDALREEGVDIATCGDRTIRCRPGLYFTPKHARVFLDAFDRVLARSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHX3</accession>
    <name>C1MHX3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50354</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055030.1">
        <property type="nucleotide sequence ID" value="XM_003054984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHX3"/>
    <dbReference type="STRING" id="564608.C1MHX3"/>
    <dbReference type="GeneID" id="9680916"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50354"/>
    <dbReference type="eggNOG" id="ENOG502QQQ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2115465at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008285">
        <property type="term" value="P:negative regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033304">
        <property type="entry name" value="DLEC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057470">
        <property type="entry name" value="Ig_CFAP65_7th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059041">
        <property type="entry name" value="Ig_DLEC1_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46348">
        <property type="entry name" value="DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46348:SF1">
        <property type="entry name" value="DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25249">
        <property type="entry name" value="Ig_CFAP65_7th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23277">
        <property type="entry name" value="Ig_Dlec1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Deleted in lung and esophageal cancer protein 1 Ig-like" evidence="2">
        <location>
            <begin position="178"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="CFAP65 seventh Ig-like" evidence="3">
        <location>
            <begin position="445"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1198" mass="130260" checksum="50575FA79E739ED6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHZ3</accession>
    <name>C1MHZ3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_37986</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055040.1">
        <property type="nucleotide sequence ID" value="XM_003054994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHZ3"/>
    <dbReference type="STRING" id="564608.C1MHZ3"/>
    <dbReference type="GeneID" id="9680888"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37986"/>
    <dbReference type="OMA" id="NENATHT"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050972">
        <property type="entry name" value="SDr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34403:SF16">
        <property type="entry name" value="GLYCINE, ALANINE AND ASPARAGINE-RICH PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34403">
        <property type="entry name" value="TOL-PAL SYSTEM PROTEIN TOLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="46"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="146"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="243"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="316"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="397"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="583"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="733" mass="75653" checksum="4F7689D008642692" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI65</accession>
    <name>C1MI65_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_50452</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055075.1">
        <property type="nucleotide sequence ID" value="XM_003055029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI65"/>
    <dbReference type="STRING" id="564608.C1MI65"/>
    <dbReference type="GeneID" id="9681181"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50452"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FFICMGK"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000002">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006522827" description="Peptidyl-prolyl cis-trans isomerase" evidence="5">
        <location>
            <begin position="25"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="36"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="202" mass="21250" checksum="4096204E320568AD" modified="2009-05-26" version="1">MFAVLRKHAILVAVVMLFASGATASDASPKVTDKVFFDVSIGGIPAGRITMGLYGDVVPKTAENFRALATGEKGTGKRGKPLHYKGSTFHRVIPNFMIQGGDFTDGNGRGGESIYGAKFADENFSLQHAGPGDLSMANSGPNTNGSQFFICTIKTSWLDGRHVVFGKVLEGMDVVYKIEAVGSSSGTPSKEVTITDSGQLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIS9</accession>
    <name>C1MIS9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_8721</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SufE family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055716.1">
        <property type="nucleotide sequence ID" value="XM_003055670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIS9"/>
    <dbReference type="STRING" id="564608.C1MIS9"/>
    <dbReference type="GeneID" id="9681080"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8721"/>
    <dbReference type="eggNOG" id="ENOG502S3NN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RTNTWHN"/>
    <dbReference type="OrthoDB" id="495661at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003808">
        <property type="entry name" value="Fe-S_metab-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597:SF5">
        <property type="entry name" value="SUFE-LIKE PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597">
        <property type="entry name" value="SULFUR ACCEPTOR PROTEIN CSDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02657">
        <property type="entry name" value="SufE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S metabolism associated" evidence="2">
        <location>
            <begin position="13"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="140" mass="15805" checksum="A4045F205EA72D72" modified="2009-05-26" version="1" fragment="single">EKLPANLKKIVGAFQMVPDPMQRYKQLLFFAAKLKGFDEKDRVEDNKVQGCVSQVWVVPRMGEDGLVYFTADSDSQLTKGLAALLCEGLRRVLAPKEIMAVEPDFVELLGLGQSLTPSRTNGFMNMLRLMQKKTLECYME</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ49</accession>
    <name>C1MJ49_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U6 snRNA phosphodiesterase 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3'-5' RNA exonuclease USB1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_50809</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055772.1">
        <property type="nucleotide sequence ID" value="XM_003055726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ49"/>
    <dbReference type="STRING" id="564608.C1MJ49"/>
    <dbReference type="GeneID" id="9680356"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50809"/>
    <dbReference type="eggNOG" id="KOG3102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EGNFATH"/>
    <dbReference type="OrthoDB" id="544844at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034477">
        <property type="term" value="P:U6 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027521">
        <property type="entry name" value="Usb1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13522">
        <property type="entry name" value="U6 SNRNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13522:SF3">
        <property type="entry name" value="U6 SNRNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09749">
        <property type="entry name" value="HVSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH61024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="313" mass="32473" checksum="201515A2FCD289BB" modified="2009-05-26" version="1">MDALAGYGSDDGGGGGGGGEDDAREDDGGGDDRADAAKKRPRDASDDDDDDAEADDAAATTRFGRVRAFEHVEGNFATHVRAPIAFPSDASTTDALRASLRAMRAKMPSLRAIGDDAPAAPATRPRADADADADADADVLPASLHVSLSRVFPVRAEARKPLVAALRARLAAANVDAFFVAATDFDVFTNDDETTTFLALRLEEASTSAAPTRERRGGFAGLIAAVDAALRAKGHPTFYADPKPHASVMWAPGNVSRALRKIVSETKGSPGLGFRGWAVPIERVACAVSGSPEVAVWARLSSAVTLPPPPSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJC9</accession>
    <name>C1MJC9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_38282</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055811.1">
        <property type="nucleotide sequence ID" value="XM_003055765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJC9"/>
    <dbReference type="STRING" id="564608.C1MJC9"/>
    <dbReference type="GeneID" id="9680492"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38282"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VHWPSEG"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="4">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH61063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="319" mass="35317" checksum="C4BAEE67D455DE29" modified="2009-05-26" version="1">MPLVGLGTWQAPVGVVGAAVADAISRRGYAHVDCAAAYANEEEVGDALRDAMASGAIARESLFVTSKLWNDRRRPRDVRAGLEQTLRDLKLDYLDLYLIHWPVVWRRGTLMQRDGDASIAECWRALEALVDEGKIRSIGVSNFDEAQLEELMRTARIAPAVNQIERHPKLPQDALVRYCQERGIVVTAYSPLARGGALFADPVVSDIAEKHSVAPAQVLLRWSVQRGVVVVPKSVTPSRIEANADLWGFELDASDVEALSTLEDGESVVASPWGTKQKKNVVLRPLLTAIMWPVSKIVRVDVQRMGRSGFWRWAWSEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJZ7</accession>
    <name>C1MJZ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64135</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056301.1">
        <property type="nucleotide sequence ID" value="XM_003056255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJZ7"/>
    <dbReference type="GeneID" id="9681657"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64135"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Right handed beta helix" evidence="1">
        <location>
            <begin position="612"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="787" mass="86346" checksum="4C8C7DD50774D5E1" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK59</accession>
    <name>C1MK59_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_13780</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055938.1">
        <property type="nucleotide sequence ID" value="XM_003055892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK59"/>
    <dbReference type="STRING" id="564608.C1MK59"/>
    <dbReference type="GeneID" id="9681469"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13780"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552819at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="4">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="149" mass="15491" checksum="CFBF6771171438E3" modified="2009-05-26" version="1" fragment="single">MLNRHARSITELGCNQNRGSDILIPGSAVNQDGRSSSLTAPNGPSQRRVMQSAMSNTDFVGSCMSLLQLHGTGTSLGDPIEIGAASAALVGDFVRKKGALPLALGAPKSRIGHAEPASGAVGILFASMGYNAEVRPTMHLRSMNPHLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML27</accession>
    <name>C1ML27_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_25062</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RING-box family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056486.1">
        <property type="nucleotide sequence ID" value="XM_003056440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML27"/>
    <dbReference type="STRING" id="564608.C1ML27"/>
    <dbReference type="GeneID" id="9681998"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25062"/>
    <dbReference type="eggNOG" id="KOG2930">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NACPLDN"/>
    <dbReference type="OrthoDB" id="8962942at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031463">
        <property type="term" value="C:Cul3-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000273">
        <property type="entry name" value="E3 ubiquitin-protein ligase RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="30"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH59862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="105" mass="12033" checksum="07A0307C827F127C" modified="2009-05-26" version="1">MEKLSSRTRFEVKKWNAVAVWSWSICTDTCAICRNSLHEPSIEYQANPSSASEEGLSIAWGNCGHVFHLDCISKWLRTRSNCPLCNKEWEFAKIEKIQLPVMGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML87</accession>
    <name>C1ML87_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_31778</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">TFIIA is a heterodimer of the large unprocessed subunit 1 and a small subunit gamma. It was originally believed to be a heterotrimer of an alpha, a beta and a gamma subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TFIIA subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056515.1">
        <property type="nucleotide sequence ID" value="XM_003056469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML87"/>
    <dbReference type="STRING" id="564608.C1ML87"/>
    <dbReference type="GeneID" id="9681569"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31778"/>
    <dbReference type="eggNOG" id="KOG3463">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QYYELYR"/>
    <dbReference type="OrthoDB" id="586585at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10014">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10145">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.190:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.18.10:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.190">
        <property type="entry name" value="Transcription factor IIA gamma subunit, alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009083">
        <property type="entry name" value="TFIIA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003194">
        <property type="entry name" value="TFIIA_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015871">
        <property type="entry name" value="TFIIA_gsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015872">
        <property type="entry name" value="TFIIA_gsu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10966">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02751">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02268">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009415">
        <property type="entry name" value="Hum_TFIIA_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit N-terminal" evidence="8">
        <location>
            <begin position="3"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit C-terminal" evidence="9">
        <location>
            <begin position="59"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00064681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="111" mass="12303" checksum="4E393412FE3E2AA6" modified="2009-05-26" version="1">MTYYELYRRSTLGMTLTDALDEMVTNFELTPSVAMKVLVQFDKCMSEALNRVKAKTTFKGNLGTYRFCDNVWTFILSDVTFSTSGAGGEIATATLDKLKIVACDGRTTSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLE4</accession>
    <name>C1MLE4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_55683</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056152.1">
        <property type="nucleotide sequence ID" value="XM_003056106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLE4"/>
    <dbReference type="STRING" id="564608.C1MLE4"/>
    <dbReference type="GeneID" id="9681831"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55683"/>
    <dbReference type="eggNOG" id="ENOG502QQ9W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="549342at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097542">
        <property type="term" value="C:ciliary tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040369">
        <property type="entry name" value="ARMC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048959">
        <property type="entry name" value="ARMC9_ARM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056327">
        <property type="entry name" value="ARMC9_CTLH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14881">
        <property type="entry name" value="LISH DOMAIN-CONTAINING PROTEIN ARMC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14881:SF4">
        <property type="entry name" value="LISH DOMAIN-CONTAINING PROTEIN ARMC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21050">
        <property type="entry name" value="ARMC9_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23138">
        <property type="entry name" value="CTLH_Armc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARMC9 CTLH-like" evidence="6">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="LisH" evidence="5">
        <location>
            <begin position="581"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="830" mass="92352" checksum="81626E583E0358F7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM81</accession>
    <name>C1MM81_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_62405</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056888.1">
        <property type="nucleotide sequence ID" value="XM_003056842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM81"/>
    <dbReference type="GeneID" id="9682793"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62405"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="142" mass="15097" checksum="F318C6827771D9A1" modified="2009-05-26" version="1">MEARGDASRGDPLADAEEGGDVWKALDGIFADMDARGPGSGGEEHDALADTVEALRGLLDMHAQLRSKSLALAAKRVEIVRERDAALDRLARLTAAGERGRRDRADANGRAEPEAISGSHRAEGKRPRSPPPRGRRPGTSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM91</accession>
    <name>C1MM91_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">60S ribosome subunit biogenesis protein NIP7 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_32422</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with pre-ribosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the NIP7 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057360.1">
        <property type="nucleotide sequence ID" value="XM_003057314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM91"/>
    <dbReference type="STRING" id="564608.C1MM91"/>
    <dbReference type="GeneID" id="9682799"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32422"/>
    <dbReference type="eggNOG" id="KOG3492">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LISMGTC"/>
    <dbReference type="OrthoDB" id="27490at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042255">
        <property type="term" value="P:ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21146">
        <property type="entry name" value="Nip7_N_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21151">
        <property type="entry name" value="PUA_Nip7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.10:FF:000002">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.220:FF:000001">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040598">
        <property type="entry name" value="NIP7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055359">
        <property type="entry name" value="Nip7_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016686">
        <property type="entry name" value="Ribosomal_synth_fac_NIP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005155">
        <property type="entry name" value="UPF0113_PUA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17833">
        <property type="entry name" value="pre-PUA_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03657">
        <property type="entry name" value="UPF0113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017190">
        <property type="entry name" value="Rbsml_synth_fac_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88802">
        <property type="entry name" value="Pre-PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUA" evidence="7">
        <location>
            <begin position="95"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="185" mass="20869" checksum="05CE44519D816B97" modified="2009-05-26" version="1">MRPLEESEIQQVFEKLFKFVGKNLKNIVDRADQPHCFRLHKKRVYYVREDIMKRAVSVARDQLVSLGVCVGKFTHSDKFRLTIGALDLLAAHAKHKMWVKPTSEMSFLYGNHLLKSGLGRITENTPANQGVVVYSMSDVPLGFGVAAKSTQDCRKLDASSIVAFHQADVGEYLRAEDDMVQGKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMB9</accession>
    <name>C1MMB9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56471</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056903.1">
        <property type="nucleotide sequence ID" value="XM_003056857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMB9"/>
    <dbReference type="STRING" id="564608.C1MMB9"/>
    <dbReference type="GeneID" id="9682816"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56471"/>
    <dbReference type="eggNOG" id="ENOG502QTIU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ERAINGW"/>
    <dbReference type="OrthoDB" id="512800at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="411"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="705" mass="73909" checksum="B09C9B97E6E695A2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMG4</accession>
    <name>C1MMG4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-methionine-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_56520</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056924.1">
        <property type="nucleotide sequence ID" value="XM_003056878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMG4"/>
    <dbReference type="STRING" id="564608.C1MMG4"/>
    <dbReference type="GeneID" id="9682840"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56520"/>
    <dbReference type="eggNOG" id="KOG1635">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YQSAVWP"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050162">
        <property type="entry name" value="MsrA_MetSO_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42799">
        <property type="entry name" value="MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42799:SF2">
        <property type="entry name" value="MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="8">
        <location>
            <begin position="16"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="196" mass="21123" checksum="CAF1E2BCC2C0362D" modified="2009-05-26" version="1">MAAFSALAAPAAHPARETFSSIEGVLSTRVGYTGGDAPSPSYGSVCAGDGHTEALKIEFDPSVVSYRSLLDVFLAQHDPCVSFTTQYQSAVWPTTEAQKNAVMDALDAYEAKRGRAAMTTVAPPKAWHDAEWYHQRYNAKNKIRLALFAGVFACNALPHGSFPGQEQLKTVLGGLVFLSLLPQLFAPIDNVLSKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMH5</accession>
    <name>C1MMH5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PIH1 domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_62486</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIH1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056926.1">
        <property type="nucleotide sequence ID" value="XM_003056880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMH5"/>
    <dbReference type="STRING" id="564608.C1MMH5"/>
    <dbReference type="GeneID" id="9682849"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62486"/>
    <dbReference type="eggNOG" id="KOG4356">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MPLEHIN"/>
    <dbReference type="OrthoDB" id="546764at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00298">
        <property type="entry name" value="ACD_sHsps_p23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050734">
        <property type="entry name" value="PIH1/Kintoun_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012981">
        <property type="entry name" value="PIH1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041442">
        <property type="entry name" value="PIH1D1/2/3_CS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997:SF0">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08190">
        <property type="entry name" value="PIH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18201">
        <property type="entry name" value="PIH1_CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIH1 N-terminal" evidence="4">
        <location>
            <begin position="44"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="PIH1D1/2/3 CS-like" evidence="5">
        <location>
            <begin position="300"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="379"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="438"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="452"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="501"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00040540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="541" mass="58531" checksum="FCAFB2B81DBECA6D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMS3</accession>
    <name>C1MMS3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_44118</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056979.1">
        <property type="nucleotide sequence ID" value="XM_003056933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMS3"/>
    <dbReference type="STRING" id="564608.C1MMS3"/>
    <dbReference type="GeneID" id="9682894"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44118"/>
    <dbReference type="eggNOG" id="ENOG502RZ2W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GYKHFET"/>
    <dbReference type="OrthoDB" id="566238at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043828">
        <property type="term" value="F:tRNA 2-selenouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058840">
        <property type="entry name" value="AAA_SelU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017582">
        <property type="entry name" value="SelU"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008750">
        <property type="entry name" value="PRK11784.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008752">
        <property type="entry name" value="PRK11784.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03167">
        <property type="entry name" value="tRNA_sel_U_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30401">
        <property type="entry name" value="TRNA 2-SELENOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30401:SF0">
        <property type="entry name" value="TRNA 2-SELENOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26341">
        <property type="entry name" value="AAA_SelU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0711">Selenium</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="25"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="384" mass="43007" checksum="3C9DF3CEC62D7B3C" modified="2009-05-26" version="1">MGPRIRKVYPDDPSFEPADWDVICDVRSPSEWAEDHVPLSISAPVLDDDERARVGTIYKRESPFLAKKVGASLVAKNLSKIIDAHFAHREKDTKVLVYCWRGGERSLSLAHVLSRIGFTVGIVPGGYKRYRAGVLEFLRSMDGFRYHLVAGKTGCAKGKMLETLEAQGAQVLDLEVMAQHRGSVLGEDPETKFSQPSQKAFDTRLWEKARTFDRTRPIFVEGESSMIGKVQIPKNTWKGMRAGTVTLLEVPMASRVKWIRAGYKHFETTEVPRLIEKLNVLVQKVGRKKVEEWEEMVAAERWDEFVEDILVNHYDSAYGEAAKRSGRDDAAAEFLMLPDTEDETYAAAAAELIRKYDVSVPAAEAEAVETETETEAEAASAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN08</accession>
    <name>C1MN08_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="13">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_46863</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 18">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="13"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057499.1">
        <property type="nucleotide sequence ID" value="XM_003057453.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MN08"/>
    <dbReference type="GeneID" id="9682938"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46863"/>
    <dbReference type="eggNOG" id="KOG0261">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AVCPPYN"/>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02736">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02583">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035698">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035697">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015700">
        <property type="entry name" value="RPC1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="15">
        <location>
            <begin position="263"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="987"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="991"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1022"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1032"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1048"/>
            <end position="1058"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH59144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1591" mass="172649" checksum="AB4E825402E40BA9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN21</accession>
    <name>C1MN21_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Wd-40 repeat family protein/notchless protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_44135</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057504.1">
        <property type="nucleotide sequence ID" value="XM_003057458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN21"/>
    <dbReference type="STRING" id="564608.C1MN21"/>
    <dbReference type="GeneID" id="9682467"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44135"/>
    <dbReference type="eggNOG" id="KOG0271">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AWEPYHR"/>
    <dbReference type="OrthoDB" id="10267436at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012972">
        <property type="entry name" value="NLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF0">
        <property type="entry name" value="NOTCHLESS PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08154">
        <property type="entry name" value="NLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NLE" evidence="7">
        <location>
            <begin position="30"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="122"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="176"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="361"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="403"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="445"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="478" mass="51769" checksum="17528FD10F803EE3" modified="2009-05-26" version="1">MDGTAKPSSSSAATATASASAAAGDRANVIAQLEDADGNPAGPQLDLPHDADHTQLETLLNALLQNEDKVPFAFYAADAEVIGPLGAHLAKRGASTETVLKIVYQPQALFRVRPVTRCSSAIPGHAEAVLSVAFSPDGKNLASGSGDTTIRLWNHDTETPKATLKGAFYLTLVPIRPRHSNWVLCIAWSPDARLLASGSMDKDVRLWSTTGEARGGPMRGHRKHVTALAWEPAHVRYPPERLASASADGTARWGGEGLIYTASRDTTIICWDAKDGKVVRQLKGHGHWVNTLALSNEYATRTGAFDHKAIAPANDEEGKRMARERYDVAMAGQPERLVSGSDDFTMFLWTPETSKSPTRRMTGHVQLINHVVFSPDTKLIASASFDKAVKLWDGKTGEFIATMRGHVGPVYQIAWSADSRMVVSGSKDSTLKVWSARTRKLELDLPGHADEVFAVDWSPIGTRAASGGKDKMLRLWRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN72</accession>
    <name>C1MN72_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ring PHD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_39051</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057053.1">
        <property type="nucleotide sequence ID" value="XM_003057007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN72"/>
    <dbReference type="GeneID" id="9682969"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39051"/>
    <dbReference type="eggNOG" id="KOG0825">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498914at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047157">
        <property type="entry name" value="PHRF1/Atg35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618:SF20">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="61"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="153"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="272" mass="29243" checksum="A85C7AE716AA6DFE" modified="2009-05-26" version="1">MPPTSSRFFRGATRASSSSLEDDVRALLREVRARRRRDRAREDAATEEEDDDDHDDEVITCAICLDAARSPCTLGGCAPNARASHVFCEDCITRWSAVANRCPLCKASFDVVHRRDGRSSFAVEARSPSGARGDGDDDDDDATIAALMAALDETFCEVCAGGDDEDTMLLCDGCDRGFHIACLSPPLTALPAEEEEWRCPRCVDGTAEEEAADEAMDVADGEDAAAAAGDDDDDEEEEEVVVLDENAPPSPRAKTATALESFRYRGGGRVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNA8</accession>
    <name>C1MNA8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_44144</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057547.1">
        <property type="nucleotide sequence ID" value="XM_003057501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNA8"/>
    <dbReference type="GeneID" id="9682986"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44144"/>
    <dbReference type="eggNOG" id="ENOG502QWNX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WEMPVLI"/>
    <dbReference type="OrthoDB" id="417952at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="282" mass="30781" checksum="8C835DC3575A9938" modified="2009-05-26" version="1">MATASASTGAPTVYALDFDGVVCDSEPESSISGWTHARALWPEIFVDDSEATTRRVLDGLKRTRPVVETGFENTLLARCVYEEIPGYSVDEILASWGALMPPLMERWNLDRASMVSGYGAIRDDWMEADLAGWLAPNLIYPGIGEACNVAEASSACDVFIVTTKQARFAAAIMEEKARSANLVVPETRLFSQCVSGIPKTAVLRELGDAAAEGARKVFVEDKMSTLEKVCATEGLEDWELFLVDWGYNTPEERARAEANPRITVWGLEDFVRDLEAAAAAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNL9</accession>
    <name>C1MNL9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55952</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057130.1">
        <property type="nucleotide sequence ID" value="XM_003057084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNL9"/>
    <dbReference type="GeneID" id="9682569"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55952"/>
    <dbReference type="OMA" id="ERHEARC"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="412" mass="44444" checksum="A514F6574587D63F" modified="2009-05-26" version="1">MALARDLEQAKRETQSAEARARKLSGFVDGHALARRQHSKVHDDAVDAAAKERVAGEVAARRAVRAESERDDARARSAASERVVEALTTTIATAEKASAAKTRELESTRAELESTRTRAEATSTTLAASTREARDAREALTRATRTLEASRATRDEIARELRECRKKSDEASDARDRLSATLAATSEDLRVALEARDASRASLTIARADAERHEARCLELDAAVAAAAAAAAARKDDDESARAAATTRVSELSDALALSREEIARVGRALDASTREAARASTRAATSARDSVAARADAASARDARDALVKRVNALEATLADAVSARDAARATLRATRDDAARATTLRERFFRELDARARRAEAEVIRLCRKHDDASRLAFGNRAAVDRSADRAGELEAEDEEVFQECDDDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNW8</accession>
    <name>C1MNW8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glutaredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3 7">1.11.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRDX</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_70211</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[glutaredoxin]-dithiol + a hydroperoxide = [glutaredoxin]-disulfide + an alcohol + H2O</text>
            <dbReference type="Rhea" id="RHEA:62624"/>
            <dbReference type="Rhea" id="RHEA-COMP:10729"/>
            <dbReference type="Rhea" id="RHEA-COMP:10730"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.25" evidence="3 7"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056717.1">
        <property type="nucleotide sequence ID" value="XM_003056671.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MNW8"/>
    <dbReference type="GeneID" id="9682623"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70211"/>
    <dbReference type="eggNOG" id="KOG0541">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SCIDNML"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0711">Selenium</keyword>
    <keyword evidence="9" id="KW-0712">Selenocysteine</keyword>
    <feature type="domain" description="Redoxin" evidence="8">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-standard amino acid" description="Selenocysteine" evidence="9">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="18471" checksum="8C7131059A3ED26D" modified="2009-05-26" version="1">MVIKVGDTFPAVQLDKDFPPDFKVDMTSRLAGKKTIVVGLPGAFTPTUSTCQVPGYLAGQDALKAAGIDEVLVYCVNDAAVMSAWADHMKIAGSNLTFLCDPRLELTKALGLELNHPGPMSKLGNTRCKRFAAYVVDGVVKHIEVSEAEDDPAGDDRPEASCIDNMLAKIAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNX2</accession>
    <name>C1MNX2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_62079</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057186.1">
        <property type="nucleotide sequence ID" value="XM_003057140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNX2"/>
    <dbReference type="GeneID" id="9682169"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62079"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="184"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="392" mass="44105" checksum="131AB20E1A5FE325" modified="2009-05-26" version="1">MNDLDFAEALRPVSICKGAGEVTFDHGKLIHDVDAVPPAVYVVTKGLFHAHDREGKLVTTIKPGEFIGSVSYFFDVFTHHKVTAAPLAEGEDAETKEKPMCYAIPWIGMAAAKTTKELAVIYQQISWWAHTIRMDVGRLQQAQARRAEKVFEINDEVLRVTTDLKCALDERHPGTLAEDLTVEQFAKSLYEVAYIPNAGEHTFEPGQEIIKYNSKPIAVWVVLEGTFEAFNHDKKRVNIFHPGDLLATVSVCYDAYTHNNVIAADVGPEAPPARAYAIPMTALPEIMRMSKILRPLYDLIYKTAAQLRPDAGLLPGRLGRDEWVEHRHLMSPFRQNLDVGLGMRLPGNGDKVLYNSRPLEYEGSRPERDFDTKHPDWAGKGFRKMNIHYVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP17</accession>
    <name>C1MP17_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_56111</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057206.1">
        <property type="nucleotide sequence ID" value="XM_003057160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP17"/>
    <dbReference type="STRING" id="564608.C1MP17"/>
    <dbReference type="GeneID" id="9682183"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56111"/>
    <dbReference type="eggNOG" id="KOG1137">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MWTDEGR"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07714">
        <property type="entry name" value="RNaseJ_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055132">
        <property type="entry name" value="RNase_J_b_CASP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43694">
        <property type="entry name" value="RIBONUCLEASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43694:SF1">
        <property type="entry name" value="RIBONUCLEASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22505">
        <property type="entry name" value="RNase_J_b_CASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="8">
        <location>
            <begin position="160"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="635"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="755"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="813" mass="87208" checksum="ACC0778F597A384F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP99</accession>
    <name>C1MP99_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_49506</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Binds to the translation initiation factors TIF3E1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056784.1">
        <property type="nucleotide sequence ID" value="XM_003056738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP99"/>
    <dbReference type="STRING" id="564608.C1MP99"/>
    <dbReference type="GeneID" id="9682223"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49506"/>
    <dbReference type="eggNOG" id="KOG3301">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WIFKNIT"/>
    <dbReference type="OrthoDB" id="1697570at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000021">
        <property type="entry name" value="40S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_uS4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005710">
        <property type="entry name" value="Ribosomal_uS4_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003139">
        <property type="entry name" value="PRK04051.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01018">
        <property type="entry name" value="uS4_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF5">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="11">
        <location>
            <begin position="8"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding S4" evidence="10">
        <location>
            <begin position="109"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="162"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00064713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="196" mass="22714" checksum="628336F3FA5C8687" modified="2009-05-26" version="1">MPSSTFYRSYSKTFKKPRRPFEKERLDNELKTVGEFGLRNKRELWRVQFALNKLRNAARVLLTLDEKDPKRIFEGEAIMRRMYRYGLLDETQDKLDYVLALSADAFLERRLQTLVFKLGLAKSVHHARVLIRQRHIRVGKQIVNVPSFLVRTDSQKHIDFALNSPLGGGRPGRVKRKRMAAAGRGGGDDDAEEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPA7</accession>
    <name>C1MPA7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS15c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_32255</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057253.1">
        <property type="nucleotide sequence ID" value="XM_003057207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPA7"/>
    <dbReference type="STRING" id="564608.C1MPA7"/>
    <dbReference type="GeneID" id="9682692"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32255"/>
    <dbReference type="eggNOG" id="KOG2815">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IMQISAH"/>
    <dbReference type="OrthoDB" id="364880at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_uS15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_uS15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15, BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321:SF26">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="148" mass="15966" checksum="AC9E1379FC49984C" modified="2009-05-26" version="1">MAAMMTTAVLVRASAPRTSVTSSSGATGFKTVVRATPVSLNVAARPVANRAASLQVVAANKMSRPNLADMEQFKEGPNDTGSSSLQIALLTKRIESLTEHLLVNKKDYACQRGLRMLLGQRNRLSKYLLKKNPAQHAKVYAALGLRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPI0</accession>
    <name>C1MPI0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56913</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057961.1">
        <property type="nucleotide sequence ID" value="XM_003057915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPI0"/>
    <dbReference type="GeneID" id="9683093"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56913"/>
    <dbReference type="eggNOG" id="ENOG502SXFB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498741at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="177" mass="18427" checksum="5DEF8A97301F1BF9" modified="2009-05-26" version="1">MNVHAIASRARAPVRVSRAGSRLGSSSRAASSAAPRDRATSAATSAVISSKRAPRLLRGGVATLGALPSSAVVAIATPSSLAPLDDRSPSPRAPTTATGGRRRGDVVVSRGLPIPIIGGLFTPPVLAVMYVFVCIRFWLGYNKTSFTEKNKAMMVGLWPVLAVASASFRENLKKAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPL2</accession>
    <name>C1MPL2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56947</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057975.1">
        <property type="nucleotide sequence ID" value="XM_003057929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPL2"/>
    <dbReference type="GeneID" id="9683413"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56947"/>
    <dbReference type="OMA" id="TRMRRCE"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052729">
        <property type="entry name" value="Acyl/Acetyltrans_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47237:SF2">
        <property type="entry name" value="BLL4206 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47237">
        <property type="entry name" value="SLL0310 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="107"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="489" mass="51887" checksum="6757B4CC63A5A7B3" modified="2009-05-26" version="1">MAPVCDVLCASPAAAILSTAVCRQRARSTRTSSFLSEISFASSAVMIARASCRATPAAVPRPRASSPDAPRRRRRRPRRHASSPPEVVNPELSYDEEFCIVDKGCAHVMRQLRGADDVAKLETLLAEVAFDASEDEWIALLSGGGAEDAEEDATATATATATGTGGARRRSPLHGATGVFDERDDLVALACTTVYDRVGVGDASMSTSTSTSTAAAREGGGGGRFAWCGNVVVRNDYRKLGVASMVLRAALEETSSKGAREVYLDASDMGVKLYQRAGFVATSRVRRYALRDDRDAASSNAAAAAAAAAPPASTRDEDDDVDDFDDDDFERVVAADAGIFGARRAALLRAWRSTAPGCFAWDPEVGYACAHARGSKLYVGPSGVFENVPVEAVSLFFERVIRLAVGEMRARDDLDGVVAYVPEGLEEEEEGDDDDDDDSNAAAAALTRAGFVFEERTTRMRRCEGDDRAPPVALGDASRCLTIASLDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ38</accession>
    <name>C1MQ38_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46995</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057691.1">
        <property type="nucleotide sequence ID" value="XM_003057645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ38"/>
    <dbReference type="STRING" id="564608.C1MQ38"/>
    <dbReference type="GeneID" id="9683497"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46995"/>
    <dbReference type="eggNOG" id="KOG0211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LWEFIKI"/>
    <dbReference type="OrthoDB" id="496790at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="88"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="211"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="250"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="489"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="658" mass="71513" checksum="4904A2575691095D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQA7</accession>
    <name>C1MQA7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_57219</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058095.1">
        <property type="nucleotide sequence ID" value="XM_003058049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQA7"/>
    <dbReference type="STRING" id="564608.C1MQA7"/>
    <dbReference type="GeneID" id="9683533"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57219"/>
    <dbReference type="eggNOG" id="ENOG502S3QK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CARETIE"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052408">
        <property type="entry name" value="Exonuclease_MUT-7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765">
        <property type="entry name" value="3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765:SF2">
        <property type="entry name" value="EXONUCLEASE MUT-7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="87"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="3">
        <location>
            <begin position="853"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="891" mass="93321" checksum="85DEA02599EDBC26" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRF1</accession>
    <name>C1MRF1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_67668</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057916.1">
        <property type="nucleotide sequence ID" value="XM_003057870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRF1"/>
    <dbReference type="GeneID" id="9683354"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67668"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="264" mass="28450" checksum="C98D5155AE84E5E9" modified="2009-05-26" version="1">MCASTLSVPRPAASAAFFSASRIHPVSAPGGAVTGNQSPARCLSSGGKFFSHILCGGGPVNTTSFQIPCAPERHTEACPPPHVTAASSAAFTAASKSAPFPRPVLKLATTRPPGDSTLAISSHASLSVSLVSTLLFSSNRSTTRPAIVLSFSRAAAFLTSSNASPMRIVTAPKISSFSKPKYFLARYMIGPLSSHPMRCLRNFPRGYKRVNSRAVLVRFGVLQHLQRPELARRFLEERHPGPDRHRPVRRRREVRGESPREVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRM2</accession>
    <name>C1MRM2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_49597</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058899.1">
        <property type="nucleotide sequence ID" value="XM_003058853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRM2"/>
    <dbReference type="STRING" id="564608.C1MRM2"/>
    <dbReference type="GeneID" id="9683972"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49597"/>
    <dbReference type="eggNOG" id="KOG0092">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PKNEPQC"/>
    <dbReference type="OrthoDB" id="63533at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01860">
        <property type="entry name" value="Rab5_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000687">
        <property type="entry name" value="Ras-related protein RABF2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="195" mass="21099" checksum="0099989B69803E38" modified="2009-05-26" version="1">MSVMQAKLVLLGDMGAGKSSLVLRFVKGQFFDYQESTIGAAFLTQCVAVNDATVKFEIWDTAGQERYHSLAPMYYRGAAAAIIVYDISSQSSFARAKSWVKELQRQGNASLVMALAGNKADLSAEKREVEASEAEAYAEENGLFFMETSAKTAANVNDLFYEIARKLPRTAAPSTPAPGVVLDSRRGAQTKSACC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS95</accession>
    <name>C1MS95_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47402</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059011.1">
        <property type="nucleotide sequence ID" value="XM_003058965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS95"/>
    <dbReference type="GeneID" id="9684083"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47402"/>
    <dbReference type="OMA" id="WPEGKFT"/>
    <dbReference type="OrthoDB" id="10671998at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="34251" checksum="018EFF423375C4B5" modified="2009-05-26" version="1">MGVLAFGDASTWATRATESAAAATTATATTATTRAPTPSAASEGGVVAPSATKRKVGDVVSLASVVRSTPTAKATPGGSATPRSNPNFAPRNAWPEGKFTIKYPKGYDPNTKTFATAGAGANVVVEKLPAAKRAAAAAAAAAREVAAAEAREAAEKASAAAAEALCLDAEYMERVRAQREARRVALEKKRNAGGGGSNAPAVAVAKLPEPEPDAALMRRVGVDDAYMARLKQQKEERERLKQAKALKAKAWSSAGAGGSNALAGAVTPAKTLTLEDFDGDEEKFYEATYEQRAREQAAQRALVAATRKQNAEAAAAAGTIGGGTNGKQKRRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSR4</accession>
    <name>C1MSR4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_26712</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058371.1">
        <property type="nucleotide sequence ID" value="XM_003058325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSR4"/>
    <dbReference type="STRING" id="564608.C1MSR4"/>
    <dbReference type="GeneID" id="9683834"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26712"/>
    <dbReference type="eggNOG" id="ENOG502QTFW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WRFAGMP"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007402">
        <property type="entry name" value="DUF455"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011197">
        <property type="entry name" value="UCP012318"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42782:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42782">
        <property type="entry name" value="SI:CH73-314G15.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04305">
        <property type="entry name" value="DUF455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012318">
        <property type="entry name" value="UCP012318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="276" mass="31040" checksum="73081512355BF3ED" modified="2009-05-26" version="1" fragment="single">MAPEKILAKCTLEEAAFRVLNTPSAHDKALMTEEIHSMWRTGVMTVTHDLDAPAPRQLERPARDARVKLVEPSCAPRLGKGGSPESRVAILHSLAHIESWAIDLSWDAIARFGRAEKMPRKFFEDFLAVAADEARHFSLLAARLVELGSSYGALTAHDGLWESATETRDSLEARLVIEHCVHEARGLDVLPGTIAKFRRFGDDPSADLLEHVIYPEEITHCAAGVRWFTYLQNRMGGALVRFHVIVRKHFKGILKPPFNDEARSRAGFQREWYEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSX9</accession>
    <name>C1MSX9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protein ATG12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_9616</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Forms a conjugate with ATG5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATG12 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058399.1">
        <property type="nucleotide sequence ID" value="XM_003058353.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSX9"/>
    <dbReference type="STRING" id="564608.C1MSX9"/>
    <dbReference type="GeneID" id="9684199"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9616"/>
    <dbReference type="eggNOG" id="KOG3439">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EHIYLYI"/>
    <dbReference type="OrthoDB" id="10003551at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01612">
        <property type="entry name" value="Ubl_ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000150">
        <property type="entry name" value="Ubiquitin-like protein ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007242">
        <property type="entry name" value="Atg12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385">
        <property type="entry name" value="AUTOPHAGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04110">
        <property type="entry name" value="APG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0072">Autophagy</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="84" mass="9315" checksum="ED00628BD90706EB" modified="2009-05-26" version="1" fragment="single">KVVVLLKATGDAPILKQNKFKVNASDPFAKVVQFLSAQLGRKRVFVYLNSAFTPSYDESVANLYAWHGVEGKLVVNYALQQAWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTE9</accession>
    <name>C1MTE9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_47301</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058477.1">
        <property type="nucleotide sequence ID" value="XM_003058431.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MTE9"/>
    <dbReference type="GeneID" id="9683916"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47301"/>
    <dbReference type="eggNOG" id="KOG3599">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WGVMLMC"/>
    <dbReference type="OrthoDB" id="537431at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013122">
        <property type="entry name" value="PKD1_2_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08016">
        <property type="entry name" value="PKD_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6154"/>
            <end position="6174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6267"/>
            <end position="6286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6306"/>
            <end position="6328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6379"/>
            <end position="6400"/>
        </location>
    </feature>
    <feature type="domain" description="LamG-like jellyroll fold" evidence="10">
        <location>
            <begin position="824"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="domain" description="LamG-like jellyroll fold" evidence="10">
        <location>
            <begin position="2205"/>
            <end position="2364"/>
        </location>
    </feature>
    <feature type="domain" description="LamG-like jellyroll fold" evidence="10">
        <location>
            <begin position="3848"/>
            <end position="3990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="423"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2443"/>
            <end position="2465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3427"/>
            <end position="3450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3626"/>
            <end position="3659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="4354"/>
            <end position="4376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="4528"/>
            <end position="4551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="5584"/>
            <end position="5613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="5778"/>
            <end position="5808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="5838"/>
            <end position="5869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="6542"/>
            <end position="6623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="6659"/>
            <end position="6704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="6733"/>
            <end position="6775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="7105"/>
            <end position="7171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="5631"/>
            <end position="5658"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="6505"/>
            <end position="6532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="2446"/>
            <end position="2459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="3431"/>
            <end position="3447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="3629"/>
            <end position="3651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="4358"/>
            <end position="4376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="4536"/>
            <end position="4546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="5603"/>
            <end position="5613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="5779"/>
            <end position="5800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="6549"/>
            <end position="6576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="6611"/>
            <end position="6623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="7144"/>
            <end position="7156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="7194" mass="781262" checksum="1DCCC5F33C507406" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTL5</accession>
    <name>C1MTL5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_47320</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058513.1">
        <property type="nucleotide sequence ID" value="XM_003058467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTL5"/>
    <dbReference type="GeneID" id="9684321"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47320"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="227" mass="24839" checksum="FE3C0C1530E0376F" modified="2009-05-26" version="1">MTHAVTTVLPQLPELSHELVAKRQNAARATGPRPPVKLATAFYDRRPTARLARLLNEEPELAAQTDADGEHSRSLFHYMAMRMTREIRGRMASIDAAVDHAADAVLEGMALDGVMGLEAKLASLERILSRQIAVRGEDAFAKAMNFAAAGMGITAGAASSQSQSNNAVPSRLEEEARLTPKHVRCESEGENGEVVCVLDDPLCWETQEVMRVPRDGLDHKMRHLHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTX2</accession>
    <name>C1MTX2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_18167</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059395.1">
        <property type="nucleotide sequence ID" value="XM_003059349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTX2"/>
    <dbReference type="STRING" id="564608.C1MTX2"/>
    <dbReference type="GeneID" id="9684537"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18167"/>
    <dbReference type="eggNOG" id="KOG0217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="497591at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF34">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="5">
        <location>
            <begin position="91"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="285" mass="29760" checksum="D28F4275309D3671" modified="2009-05-26" version="1">MLLTGPNMGGKSTLLRQVAVAVIMAQCGCYVPAASASLHVVDAVACRIGAGDGIASGVSTFLAEMSETSAALRRATKARSILHWSPYDRRSLLIVDELGRGTSTTDGYAIAFAVLTSIARQTRCRCLFATHFHQLAEDVGDDRGVVAAHMAAATTAREGNGNGNGGGGGGGGCFSDITFEYKLTPGPAPLGSCALNVARLAGFPEKVLKNAAEVASSSRTFIPRPKRPRPAAAAEAPGPLSPEAWQCFKEVVTDPAVRGVPGAVADDAWARKFYALWKRCRALKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTY8</accession>
    <name>C1MTY8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribokinase kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_33782</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059102.1">
        <property type="nucleotide sequence ID" value="XM_003059056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTY8"/>
    <dbReference type="STRING" id="564608.C1MTY8"/>
    <dbReference type="GeneID" id="9684555"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33782"/>
    <dbReference type="eggNOG" id="KOG2854">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CNIVGAC"/>
    <dbReference type="OrthoDB" id="414463at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01168">
        <property type="entry name" value="adenosine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052700">
        <property type="entry name" value="Carb_kinase_PfkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43320:SF1">
        <property type="entry name" value="OS01G0105900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43320">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="5">
        <location>
            <begin position="62"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="235"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="243"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="388" mass="40070" checksum="82A82476897F95FA" modified="2009-05-26" version="1">MSNPPARSPPPDVVALQPLAVIDHSVVVDDAFLRSVDGEIGGSSRVGVEELERILERAGGAHRTRAGGSAANTARALATGFRVSCALLGAVGGDDWGAVFAREMRDAGVSVDHLTTKPGLSFTGRCACLVDAETGQRTMRASLQDAVRLTPEEVRPGSFVGVKWAIVNGYAFYGEGLADAAVDAAATAKCKARSTVAMHLASFEVVRHHRDALMRLLRSGKIDAVFANEEEARELLPGEDDGGGGGGGGDGGGGDGDGVASRLDAPPSASVASRLDALASTCDIAVITLGDRGCVAARGAERVRVSAFGLMPCGSGVRGSRSVVDTTGAGDLFSAGFIYGLLRGESLHRCCERGNLCGAAVVGELGGEVSEKGWAWVRVRERERILLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTY9</accession>
    <name>C1MTY9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_40091</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059103.1">
        <property type="nucleotide sequence ID" value="XM_003059057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTY9"/>
    <dbReference type="GeneID" id="9684543"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40091"/>
    <dbReference type="eggNOG" id="ENOG502S73B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RATWALH"/>
    <dbReference type="OrthoDB" id="430205at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase small" evidence="2">
        <location>
            <begin position="745"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="871" mass="87112" checksum="0868C754B93BC560" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU96</accession>
    <name>C1MU96_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_47498</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059458.1">
        <property type="nucleotide sequence ID" value="XM_003059412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU96"/>
    <dbReference type="STRING" id="564608.C1MU96"/>
    <dbReference type="GeneID" id="9684597"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47498"/>
    <dbReference type="eggNOG" id="KOG4777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MSVCVGN"/>
    <dbReference type="OrthoDB" id="1894490at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051823">
        <property type="entry name" value="ASADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718:SF1">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="439" mass="47660" checksum="3EFEA37CAD7ABE9A" modified="2009-05-26" version="1">MGGGATASDAPPGEALCRICWSAVCEYDGRPEFLSPTPCACRDERSNVHQACLERWILEARSQGRFDAGTRCHACGDPYAHPLLDETVLSASARSAIRASSLSPLNGAADDRTPLAIIGGTGYVGRSVALHLLGHPTFKIGAVVGSVATVGKPFRAVFEKKEDALVEHYGADLWKPQEFPAELMHCVVQSVEDVIADGVIKTALSFIAPEHGEIEDALARAGIKVFRRALDDAFGVEDVSVTTFQSLSGRGDAKYQRDLVMGNVYPLAGTVERTGEYQKLELRRIMPGVKRVSVAAYRVPVQKGHLVDVRVRLRTKPADARAVERAFTSFDPLARVSLPSKPRRAIYVKPIDEAPTGEEGERPPPRIGTPRPKDDHEYDGGMSVCVGNIDVDDELFDVSFCLVVNNVVRGAWGAALLNAEYWHALMTKEKEAIAGRIEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV83</accession>
    <name>C1MV83_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59091</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059624.1">
        <property type="nucleotide sequence ID" value="XM_003059578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV83"/>
    <dbReference type="STRING" id="564608.C1MV83"/>
    <dbReference type="GeneID" id="9685064"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59091"/>
    <dbReference type="OrthoDB" id="153872at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31717">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31717:SF45">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="72" mass="7912" checksum="49D5283138234036" modified="2009-05-26" version="1">MGVICALCNTSEAAIYCFNDAANLCSACDAQMHVGAHSNNKLTWKHQRVRLCETCKGEPAHATVYCEHDKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVG9</accession>
    <name>C1MVG9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59374</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060036.1">
        <property type="nucleotide sequence ID" value="XM_003059990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVG9"/>
    <dbReference type="GeneID" id="9685189"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59374"/>
    <dbReference type="eggNOG" id="ENOG502SYQH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317">
        <property type="entry name" value="BLR8090 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317:SF1">
        <property type="entry name" value="ZINC-RIBBON DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="2">
        <location>
            <begin position="65"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="2">
        <location>
            <begin position="147"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="2">
        <location>
            <begin position="225"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="298" mass="33572" checksum="09B485BF2C1A0A6A" modified="2009-05-26" version="1">MARVALASSPWRPHATPALTGGMGSRLARVRRASAPCPPPHDRGRRDTPTYNLVTWCEENFQRGLLKEYVDPDRGPTKVTRGSGYRALWKCAACGHEWRTTVNHRTKSDKPTGCPECRPPGGGPVTATPTNNFLVWCEENGERGKKLLKEYVDRDRKPTEVMRGSNYKALWKCAACDHEWRAVMCSRTRRNRLSGCPACSKRLPQSETHFFLEWCEENGERGERLSREYADPDVKPTELAYGSAYRALWKCAACDHEWRATMCNRTRSDKPAGCPKCNPPGGPRKDKSGRRVPPAATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVH7</accession>
    <name>C1MVH7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59382</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060039.1">
        <property type="nucleotide sequence ID" value="XM_003059993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVH7"/>
    <dbReference type="GeneID" id="9685477"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59382"/>
    <dbReference type="OMA" id="KFRHPRS"/>
    <dbReference type="OrthoDB" id="10563666at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="256" mass="27039" checksum="6ABF5458E278529F" modified="2009-05-26" version="1">MRVKFRHPRSKERRVDPPRASSPPSPPSVYWQCTGQESFADVKAAADAILSARWPFEPYDTDAFRRDSDGHLWDRKRGVARRGQSWKPAASLLDAGYGEGDELVCMAHLHKYWVKTCNSFSESRAAKTASVQAARGQVLRDEIIAQAGRPVCERTFKRPTGTTASFDEREKVAKAVKKAAKAKAKKSAIKAAKAAKEGPSAGGAPAAAAPNAGAAAAPPAKKSPAAAPAAKTKTTPLASTKSSTSKSLGGTAARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVX2</accession>
    <name>C1MVX2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_27633</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060113.1">
        <property type="nucleotide sequence ID" value="XM_003060067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVX2"/>
    <dbReference type="STRING" id="564608.C1MVX2"/>
    <dbReference type="GeneID" id="9685551"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27633"/>
    <dbReference type="eggNOG" id="KOG1722">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PGHGKKM"/>
    <dbReference type="OrthoDB" id="497981at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="TRASH" evidence="4">
        <location>
            <begin position="8"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="125" mass="14519" checksum="7626B0D0C62B0F08" modified="2009-05-26" version="1">MVLKTEVCRFSGLKIYPGHGMRLTKIDSQTYLFLSAKCKRLFNLRLRPAKLAWTTQYRKAHKKDAVVDAARKKKRSVRLQNRSLVSANLELITKKRAEKPEVRAAAREAALREIKERNRKNKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWC4</accession>
    <name>C1MWC4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59714</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059900.1">
        <property type="nucleotide sequence ID" value="XM_003059854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWC4"/>
    <dbReference type="GeneID" id="9685339"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59714"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="175" mass="19072" checksum="8FE666750B9FC180" modified="2009-05-26" version="1">MRVDAVVAGLGASLDLRVLFEARDLDAKVSLEFQPSAPFVSRSRVSLMEPPRTSLRIAPEGLGGLSLTDLPGVDGWLKSGAFVLFALHAVAVSFAERLRFSPTHPQPSVSTFHRFPFQLTTDTSSVIEDALVKHLVEPNGHVWDVGAWWRGRCEAAAEEEAARVERAVRERVGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWI2</accession>
    <name>C1MWI2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_18275</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060220.1">
        <property type="nucleotide sequence ID" value="XM_003060174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWI2"/>
    <dbReference type="GeneID" id="9685368"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18275"/>
    <dbReference type="eggNOG" id="ENOG502RMTT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PFFAAIW"/>
    <dbReference type="OrthoDB" id="410754at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35791">
        <property type="entry name" value="UPF0754 MEMBRANE PROTEIN YHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35791:SF1">
        <property type="entry name" value="UPF0754 MEMBRANE PROTEIN YHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="514" mass="58072" checksum="FB170A06818ADDF7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWY7</accession>
    <name>C1MWY7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-5-taurinomethyluridine 2-sulfurtransferase</fullName>
            <ecNumber evidence="3">2.8.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_4302</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5-taurinomethyluridine(34) in tRNA + S-sulfanyl-L-cysteinyl-[protein] + AH2 + ATP = 5-taurinomethyl-2-thiouridine(34) in tRNA + L-cysteinyl-[protein] + A + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:47040"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11732"/>
            <dbReference type="Rhea" id="RHEA-COMP:11733"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:87171"/>
            <dbReference type="ChEBI" id="CHEBI:87172"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.14" evidence="3"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060003.1">
        <property type="nucleotide sequence ID" value="XM_003059957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWY7"/>
    <dbReference type="STRING" id="564608.C1MWY7"/>
    <dbReference type="GeneID" id="9685092"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4302"/>
    <dbReference type="eggNOG" id="KOG2805">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LFMRNWN"/>
    <dbReference type="OrthoDB" id="3685at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061708">
        <property type="term" value="F:tRNA-5-taurinomethyluridine 2-sulfurtransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="MnmA_TRMU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="MnmA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046884">
        <property type="entry name" value="MnmA-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="MnmA-like_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933:SF5">
        <property type="entry name" value="MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933">
        <property type="entry name" value="TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03054">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20259">
        <property type="entry name" value="tRNA_Me_trans_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Rhodanese" evidence="12">
        <location>
            <begin position="6"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH55955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="311" mass="33269" checksum="3E842D2DEC2B358D" modified="2009-05-26" version="1" fragment="single">IAVGISGGVDSAVTAWILKRAGYDVVGVLMRNWDEAEETGGECAFEKDQRDAAAVARSVGIELREVDFVKEYWHAVFQPFLRDFDGGASTPNPDLACNRHIKFGSLLKHCLLDVKADVLCTGHYAKIVRGPNGVFCLHTAEDKEKDQSYFLASVKQEALRNACFPLGWLTKTEVRAIAAGPAKLPSAVTSRRSSRGICFIGRKKNFGEFVHEYLPEEGRTSEASATDSDAASGAFVSVVDGAVVGAHKGLARYTCGQGARVGGASAPWFVVGKDSRAGVTNVYVAPGSDHPALFVATAAVARCFWVEGKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXC7</accession>
    <name>C1MXC7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60106</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060670.1">
        <property type="nucleotide sequence ID" value="XM_003060624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXC7"/>
    <dbReference type="GeneID" id="9686107"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60106"/>
    <dbReference type="OrthoDB" id="498649at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="160" mass="16744" checksum="B0458D023041F141" modified="2009-05-26" version="1">MHALASSVASSHPALASSRARFTRSNARAAARVVRVVASDAKSSSSDDARTTPAIVASARAASFAAVAALASPPSAHAMEGIMSVFNGQPGLLGAACVAVCWGIPQTLGMGILAKKEEKGREILREWGVEEADVEKGNWGRIQARIKEEAIRRGVERPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXW8</accession>
    <name>C1MXW8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Dihydrolipoyl dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">DLDH2-GCSL2</name>
        <name evidence="15" type="ORF">MICPUCDRAFT_34732</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060770.1">
        <property type="nucleotide sequence ID" value="XM_003060724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXW8"/>
    <dbReference type="STRING" id="564608.C1MXW8"/>
    <dbReference type="GeneID" id="9685902"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34732"/>
    <dbReference type="eggNOG" id="KOG1335">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WASMLND"/>
    <dbReference type="OrthoDB" id="361797at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050151">
        <property type="entry name" value="Class-I_Pyr_Nuc-Dis_Oxidored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912:SF151">
        <property type="entry name" value="DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912">
        <property type="entry name" value="DISULFIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="2 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="14">
        <location>
            <begin position="96"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="13">
        <location>
            <begin position="446"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="548"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="232"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="269"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="418"/>
            <end position="421"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="10">
        <location>
            <begin position="133"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH55539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="565" mass="59905" checksum="2F099CFEA60E165A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYD1</accession>
    <name>C1MYD1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59868</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060553.1">
        <property type="nucleotide sequence ID" value="XM_003060507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYD1"/>
    <dbReference type="GeneID" id="9685714"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59868"/>
    <dbReference type="OMA" id="PWSPFFK"/>
    <dbReference type="OrthoDB" id="10496314at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="208" mass="21781" checksum="6D6298B077B8354E" modified="2009-05-26" version="1">MLAATTVAAEPLRVTARPRVAARAAARAPATTALFTKTKPPPATTKKAKPLGKKNANDRGGAKKKMSQGESMKEMSSIVAQAFALGLGVPVGVVALTEASKQLTAGADGAVASGDPGLYSFIAASVGFAGWWGAKSAARDELKRSLLAKGLDVSTVDNISVLKWVKSQDDIGKGKRAIDEIYKAYETEANPWSPFFKPVGAVPDRKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ22</accession>
    <name>C1MZ22_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_28210</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060881.1">
        <property type="nucleotide sequence ID" value="XM_003060835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ22"/>
    <dbReference type="STRING" id="564608.C1MZ22"/>
    <dbReference type="GeneID" id="9686580"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_28210"/>
    <dbReference type="eggNOG" id="KOG0410">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GTIHMAG"/>
    <dbReference type="OrthoDB" id="10268034at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="entry name" value="GTPase HflX, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045498">
        <property type="entry name" value="HflX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229:SF0">
        <property type="entry name" value="GTP-BINDING PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="GTP-BINDING PROTEIN HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19275">
        <property type="entry name" value="HflX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="6">
        <location>
            <begin position="275"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="112"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="567" mass="61026" checksum="BBD9B4F0AEA20927" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ27</accession>
    <name>C1MZ27_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Flavin-containing monooxygenase</fullName>
            <ecNumber evidence="6">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_60580</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the FMO family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="6"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060885.1">
        <property type="nucleotide sequence ID" value="XM_003060839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ27"/>
    <dbReference type="STRING" id="564608.C1MZ27"/>
    <dbReference type="GeneID" id="9686581"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60580"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VEHWRDQ"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="514" mass="56026" checksum="B0E125B0CFC13A7F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZQ1</accession>
    <name>C1MZQ1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_41358</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="6">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061259.1">
        <property type="nucleotide sequence ID" value="XM_003061213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZQ1"/>
    <dbReference type="STRING" id="564608.C1MZQ1"/>
    <dbReference type="GeneID" id="9686431"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41358"/>
    <dbReference type="eggNOG" id="KOG0343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SHYQESA"/>
    <dbReference type="OrthoDB" id="10259640at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="100"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="180"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="389"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="499"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="609"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="609"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="661"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="684"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="749" mass="78570" checksum="C055F41B05BB4416" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0U9</accession>
    <name>C1N0U9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_41620</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061455.1">
        <property type="nucleotide sequence ID" value="XM_003061409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0U9"/>
    <dbReference type="STRING" id="564608.C1N0U9"/>
    <dbReference type="GeneID" id="9687140"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41620"/>
    <dbReference type="eggNOG" id="KOG4176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RNVNTRH"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032451">
        <property type="term" value="F:demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070988">
        <property type="term" value="P:demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032857">
        <property type="entry name" value="ALKBH4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463:SF1">
        <property type="entry name" value="2-OXOGLUTARATE AND FE-DEPENDENT OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463">
        <property type="entry name" value="OXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="16"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="4">
        <location>
            <begin position="226"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="408" mass="43303" checksum="26DF80122D3A6542" modified="2009-05-26" version="1">MSPPPPRGRPPPPPSRHLYVANVGPKVGDAAEDVAAAFAAFGEVAAVQIRDPTSARCVVSMATDDAARDAIRALNDAPCAALGGRKIVVRFAGESAVATMDATTDATTDATDATTTTTKKKTNAMTQEEAWCVAARTSDDLGVPGATLILDFVTEDEEVAMLKSAEEDPRWQRLAKRRVLHYGYAFDYGTRDAKAPAGAAMPSYAAALLDRAAALTDVPGVERALRCDQLTVNEYEPGIGLAPHVDTHSAFGGTILAASCGGGAVIEFRLHERDGDGDDDASRRVPSRRAAIYLPPRSLLVMAGEARYRWAHYVPHRKRDAVKRFGGDGGGAATEIARREGKRVSFTFRETRDVAVEGPCACAWPEACDSRMGAAQLLNERARPGAVAAARRAAEAAAAFREVEIVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N112</accession>
    <name>C1N112_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_51221</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the mTERF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061491.1">
        <property type="nucleotide sequence ID" value="XM_003061445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N112"/>
    <dbReference type="STRING" id="564608.C1N112"/>
    <dbReference type="GeneID" id="9687167"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51221"/>
    <dbReference type="eggNOG" id="KOG1267">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WTVANDN"/>
    <dbReference type="OrthoDB" id="508936at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.70.10">
        <property type="entry name" value="Transcription termination factor 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003690">
        <property type="entry name" value="MTERF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038538">
        <property type="entry name" value="MTERF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13068">
        <property type="entry name" value="CGI-12 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13068:SF112">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02536">
        <property type="entry name" value="mTERF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00733">
        <property type="entry name" value="Mterf"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0806">Transcription termination</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="100"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="742"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="774"/>
            <end position="799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="799" mass="87164" checksum="576037F60029321E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1R4</accession>
    <name>C1N1R4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_51703</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061959.1">
        <property type="nucleotide sequence ID" value="XM_003061913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1R4"/>
    <dbReference type="GeneID" id="9687399"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51703"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="325" mass="35418" checksum="F3B1FC2796141930" modified="2009-05-26" version="1">MARSRPRSRARSRPSRSWKTHLSAGSLARCVAVSLSTFLPCTCSAAADEDLLCFVTGRPPAHVADALTAKYVPGMNVGDPSCCAPCEALEIALRWTNASVASVWRVFDDRRSEKNPSAPRMLDAFDEGDLERSSICSMLARYPACVARATAFLGVLGCAPGAVAYAPDLTPELRERLPTSVNATANEDAITITRRVRMCEKDAKDVFDACADVKVLSITTVGAWFGSDPNDGGARYTTPQLGDVRPVIRPETPEEPCYSVPADNGKDVYDPDSSWMQTGTWCCDDFPRVERCEGEIDWDEYPRTVENTYAASLRERGTCPPKSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1Z2</accession>
    <name>C1N1Z2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_70061</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062203.1">
        <property type="nucleotide sequence ID" value="XM_003062157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1Z2"/>
    <dbReference type="GeneID" id="9687642"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70061"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="177" mass="17678" checksum="B675DB15255B2134" modified="2009-05-26" version="1">MICAGEAIEGESVGQSCVSPVKRTNDVERKARGEEKREGKSSRNGARPAGTGVIVWESSLDDERTCAMPTTSSARGRNSDSSGKCATCPARTTAPSAAAGGAIVSTGFSSSLNHFVTRSGALVTSSVRTSTSTPRNASASVDAGLSTSSTPPGGGNSPGSVAENAAKSSSGDDSFVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N207</accession>
    <name>C1N207_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_41974</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062006.1">
        <property type="nucleotide sequence ID" value="XM_003061960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N207"/>
    <dbReference type="GeneID" id="9687649"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41974"/>
    <dbReference type="eggNOG" id="KOG3762">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AEMKCEE"/>
    <dbReference type="OrthoDB" id="515887at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="482"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily associated" evidence="8">
        <location>
            <begin position="25"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily associated" evidence="8">
        <location>
            <begin position="172"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="232"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="531" mass="56759" checksum="C33D0A86915C18B6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N212</accession>
    <name>C1N212_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41977</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062009.1">
        <property type="nucleotide sequence ID" value="XM_003061963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N212"/>
    <dbReference type="GeneID" id="9687651"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41977"/>
    <dbReference type="OMA" id="TSCHELM"/>
    <dbReference type="OrthoDB" id="414418at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07040">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF27">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="204" mass="22440" checksum="4830A3CC9EF9527A" modified="2009-05-26" version="1">MRVAGDDAPATSSGTGPPKVFVLRHEKRDPTDPRFFTPLTEEGMMDAAKTVSDDLHDLGITKIYASPFLRVLQTVEPFARRKGLLVRVDYSLYEHPEPNDEPVTALPAEFYERFPIDAAFASILDGNRIGAHNADAAALRRRLQAFLKWVVENHGADERVLLATHQTSCHELMHLQSGVEIETLDVAMGSVFELDAEAALGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N226</accession>
    <name>C1N226_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51824</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062219.1">
        <property type="nucleotide sequence ID" value="XM_003062173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N226"/>
    <dbReference type="GeneID" id="9687456"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51824"/>
    <dbReference type="OMA" id="KARWRVD"/>
    <dbReference type="OrthoDB" id="10666151at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="238" mass="25247" checksum="0214A870139FAE2E" modified="2009-05-26" version="1">MWSVGGEVKFGKGHGQDAKRGLELGIERATAAIARGTTIATTPWQPKAPEDPKARWRVDGDGARVDPSNRALDAHLRLESMVPRVRASGGGGGGGGGGGGGEESDSSSLMSDSSATSDEIRKLRRAGNKRRRAKEASGGGGGGKKSSKKDKSSKKEKKEKKEKKSKKSSKRKSGKRRRSSSGSDSDSDSDARGVDFVSGKKIKMKLEGSSKRDDVEAAKRAAYLRSLNAQISFQELTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2B6</accession>
    <name>C1N2B6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_8059</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062266.1">
        <property type="nucleotide sequence ID" value="XM_003062220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2B6"/>
    <dbReference type="GeneID" id="9687499"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8059"/>
    <dbReference type="eggNOG" id="ENOG502RXZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CEQMKEY"/>
    <dbReference type="OrthoDB" id="192915at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042415">
        <property type="entry name" value="CNPY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021852">
        <property type="entry name" value="DUF3456"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13341">
        <property type="entry name" value="MIR-INTERACTING SAPOSIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13341:SF2">
        <property type="entry name" value="PROTEIN SEELE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11938">
        <property type="entry name" value="DUF3456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912262" evidence="1">
        <location>
            <begin position="19"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3456" evidence="2">
        <location>
            <begin position="22"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="161" mass="18028" checksum="B859870B4C251532" modified="2009-05-26" version="1" fragment="single">LALLALAMSALGVQPASAIEAKCSACEAVANELQAALERERPRNHLDMRGRIDSKGVRYGKLIDYKISELRFVELLEDLCTDVGNNFQIFDADAPKKRWRTFAKKLKIKGARAKAMRAEISGYCHRLVEEQEEALQAKLYANELNATNVDEILCVELSKEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2I7</accession>
    <name>C1N2I7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51544</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061880.1">
        <property type="nucleotide sequence ID" value="XM_003061834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2I7"/>
    <dbReference type="GeneID" id="9687534"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51544"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="555" mass="59921" checksum="1D662EDDC5A9A990" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2Y2</accession>
    <name>C1N2Y2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68474</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062512.1">
        <property type="nucleotide sequence ID" value="XM_003062466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2Y2"/>
    <dbReference type="GeneID" id="9687726"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68474"/>
    <dbReference type="OMA" id="IGTPWLR"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="185" mass="21767" checksum="D1682CDC1688135F" modified="2009-05-26" version="1">MRAVRAWFSRARTKKRVRRASMTQNASTRAVTITTTPSPAATPSRVTAGRTTPRARSASPTLATRRSAFPPRRARRRRRPTGRPARASLRARSRLSSGPPRLCPRPRAARRSRRARRSRPRRRTRRGRSPRRRRRRRRRRRRRARLQPARRRQTPSRRRPGTLRRRPRSPGTRRRRIARPRAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2Z5</accession>
    <name>C1N2Z5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_21418</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062520.1">
        <property type="nucleotide sequence ID" value="XM_003062474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2Z5"/>
    <dbReference type="STRING" id="564608.C1N2Z5"/>
    <dbReference type="GeneID" id="9687731"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21418"/>
    <dbReference type="eggNOG" id="KOG0243">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ERMGRTH"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047149">
        <property type="entry name" value="KIF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970:SF12">
        <property type="entry name" value="KINESIN FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH53339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="139" mass="14895" checksum="4CCF0A9E083A3313" modified="2009-05-26" version="1" fragment="single">MNKASSRSHCVFTLRVNSTRKLPDGSTMECAGKLHMVDLAGSECAKSAGGGELDPSRERERKNINQSLLTLGRVITLLKAGGKAKGERIPYRDSKLTRLLQESLGGRCKTCVIATVSPSIMSVDETLSTLQYAQAAVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N344</accession>
    <name>C1N344_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HEMF</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_52031</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>coproporphyrinogen III + O2 + 2 H(+) = protoporphyrinogen IX + 2 CO2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:18257"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="1.3.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062314.1">
        <property type="nucleotide sequence ID" value="XM_003062268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N344"/>
    <dbReference type="STRING" id="564608.C1N344"/>
    <dbReference type="GeneID" id="9687986"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52031"/>
    <dbReference type="eggNOG" id="KOG1518">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VHANWRY"/>
    <dbReference type="OrthoDB" id="15318at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1500.10:FF:000002">
        <property type="entry name" value="oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003727">
        <property type="entry name" value="PRK05330.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF0">
        <property type="entry name" value="OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="380" mass="42709" checksum="25EA8770DB9EC96E" modified="2009-05-26" version="1">MWTPILKDFARRLSPIRAREAFARLTPSHPSFPLKKVTVRAAAPSTRTIEEEVALDEAPLTLLREGGGDDAGSMRAKFEKMIRAAQNEICSAVEELDGQKFQEDAWTRPGGGGGISRVLQGGNVFEKAGVNVSVVYGQMPPEAYRAATGEQGSGKEMIPFFAAGISSVMHPHNPMAPTVHFNYRYFETDAPEGAEAAPRAWWFGGGTDLTPSYVFPEDAAHFHGTLKDACDKHDEAFYPRFKEWADDYFIIKHRMNERRGIGGVFFDDMNDRPQEELLAFATDMAAAVVPAYVPLVAKHKDDEFTEQQREWQQMRRGRYVEFNLVYDRGTTFGLRTGGRIESILMSLPLTARWQYDMQPEEGSREADALDAFRNPRTWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3C0</accession>
    <name>C1N3C0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_48541</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062583.1">
        <property type="nucleotide sequence ID" value="XM_003062537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3C0"/>
    <dbReference type="STRING" id="564608.C1N3C0"/>
    <dbReference type="GeneID" id="9687793"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48541"/>
    <dbReference type="eggNOG" id="KOG4285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SAANWTH"/>
    <dbReference type="OrthoDB" id="511399at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044613">
        <property type="term" value="C:nuclear pore central transport channel"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044615">
        <property type="term" value="C:nuclear pore nuclear basket"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006607">
        <property type="term" value="P:NLS-bearing protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12441">
        <property type="entry name" value="RRM_Nup53_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007846">
        <property type="entry name" value="RRM_NUP35_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21527">
        <property type="entry name" value="NUCLEOPORIN NUP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21527:SF6">
        <property type="entry name" value="NUCLEOPORIN NUP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05172">
        <property type="entry name" value="RRM_Nup35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51472">
        <property type="entry name" value="RRM_NUP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6 8" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RRM Nup35-type" evidence="10">
        <location>
            <begin position="348"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="31"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="496" mass="49816" checksum="716E4D7070B625AE" modified="2009-05-26" version="1">MASFNFGAAAAPTPGAAAAPSTPLFGGGGIFGGAATPTTGGNIFGGAAPGTAPATGGFGGGAPTTPSLFGPAPGTAPATGGFGGGAATPSLFGGVPQQQQQPQPQPQSQPQPQYPQSAPRRYDSLLDGDAARGDRYGRFAIDPDPRGPDASLVEDPYYDRRGARGPASASRPFAPMLFRSSPSDRRGDPRGHDGGDPYAYSRGGGGGGYYPEDPPHSGYHGDRGGATPGDGWGSRRRSAGRGGYNTAGGGQGYFSGGVGGGTLHTPSTRGLLFSGNTPSGASGGTARRVFGGRGSSAKGDGAGGDGASPKDDGHVGTPWSKGRRRSPRLHASAADAAHTPPQGVTADIGNDCWVTVFGFAPEKVTSALREFQRDGDVVFFDAFDDGEKASSAANWTHVRFATKEGARRALLRNGTMAGGSIVGVKPLDDATRAIVEARHGGIGLASGGGGGGSVVRPSGGAAASARPHRVAPTREGVSLQPRRSFWGKVVEFIFGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3H7</accession>
    <name>C1N3H7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_68649</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062379.1">
        <property type="nucleotide sequence ID" value="XM_003062333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3H7"/>
    <dbReference type="GeneID" id="9688054"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68649"/>
    <dbReference type="eggNOG" id="ENOG502S962">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CARWCAS"/>
    <dbReference type="OrthoDB" id="241340at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002128">
        <property type="term" value="P:tRNA nucleoside ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18093">
        <property type="entry name" value="SpoU-like_TrmJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786:SF2">
        <property type="entry name" value="TRNA (CYTIDINE_URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="TRNA/RRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="6">
        <location>
            <begin position="143"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="340"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="464" mass="49049" checksum="E284522427CD2D95" modified="2009-05-26" version="1">MSASVASPSRACARWCASTSATPRPTAARVASSRRRRSCRLLLRHEETQRAAVADDANADETAAAAEEEEEEEDDDDDDDAREEVRSLLSNVCVVLCRPQGPQNIGGIARVLNNFGIADLRIVTPEPSALAPPYDAADATTDKATHPAETRATAPLAEEAHKFAVHADWLLRDARRCVDAAEALSDCVFVAATTARARENLPILDARSAVERVKVAASEGKVAIVFGNEATGLTNEELSLANVGVMIPTAGRAGAGAGGRRGEKRYTGGAGPTSLNLSHAVGVVAYELFRELGDGVVSGFNSRLITTEERTRLAEELVAARRSLDVLASSSSSSSSTSTDGEEDEEKEEGEAALLAEKERLLEEKEARAFARVLNAGPIASKDAAAFFNLARRTRGAAKFSRADDAVVAAAREVFDAATASGGGNDVGTKRLSNHVRERTGLSLSLRELDRVARAAKNASAKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N484</accession>
    <name>C1N484_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ribonuclease P</fullName>
            <ecNumber evidence="5">3.1.26.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MICPUCDRAFT_52451</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="5"/>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062954.1">
        <property type="nucleotide sequence ID" value="XM_003062908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N484"/>
    <dbReference type="STRING" id="564608.C1N484"/>
    <dbReference type="GeneID" id="9688394"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52451"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CIDINPV"/>
    <dbReference type="OrthoDB" id="46913at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031595">
        <property type="entry name" value="PRORP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13547">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13547:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBONUCLEASE P CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16953">
        <property type="entry name" value="PRORP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="17">
        <location>
            <begin position="207"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="PRORP" evidence="16">
        <location>
            <begin position="577"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="500"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH52893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="726" mass="77710" checksum="17DE219D3049214D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N486</accession>
    <name>C1N486_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_66696</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062955.1">
        <property type="nucleotide sequence ID" value="XM_003062909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N486"/>
    <dbReference type="GeneID" id="9688192"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66696"/>
    <dbReference type="eggNOG" id="ENOG502RZCC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="545589at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="217" mass="24414" checksum="3DAAE7A590B5C8F3" modified="2009-05-26" version="1">MSRLSGPWGPLGTITQTEVSPYFGHSTFKYHFDPCQAAAKNGHLEVIRWLLANKCPWDVTTVGNGAAKHGHLKVLQFAIEKGFHPDESTCAAVASKGNLRMLKWLRKQNCPWNRETCDQAANKGHLFVLQWAAENGCPVDATTTQAAASGVHLEPLRWLVERGCPWNVEICNSIVDRWKCLNNPKHVEKIKEWMYWRLAKERGCPERDVPARTDAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N496</accession>
    <name>C1N496_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_52468</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062959.1">
        <property type="nucleotide sequence ID" value="XM_003062913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N496"/>
    <dbReference type="STRING" id="564608.C1N496"/>
    <dbReference type="GeneID" id="9688193"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52468"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FMQMAEK"/>
    <dbReference type="OrthoDB" id="539167at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24203:SF45">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24203">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="STI1" evidence="5">
        <location>
            <begin position="110"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="5">
        <location>
            <begin position="159"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="230"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="263"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="296"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="204"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="218"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="355" mass="36530" checksum="46185A0E2FC43849" modified="2009-05-26" version="1">MAGEMPDGFGMPGGPGAGGMPPGLAQMMAGAGGPGGAPFDMSKIKEMLEDPAIKDMAKQIAEDPSFKTMAENMQSAMANGGMPGMLGGAGGAAAAGPMGMPPGLDPAAAMEAMQGVMQNPAFMQMAEKLGKSMMADPAMANMMSQMQDPETTEKMKAKMEALKEDPEMADIMKEIESGGPAAMMKYWNDPKVLQKISGAMGDVMPGFGGAAAPPAAPAEEEEEEEEEEEDGEETVHTAASAGEAETLQELIDGGADVNATDGEGRTALHFACGYGEIKCATILCDAKADVNAVDKNKNTPLHYAAGYGNGEVVKLLVDAGASVTLRNLDGKSPLDVAKLNDQDEVVAALEADVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N506</accession>
    <name>C1N506_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_6601</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062885.1">
        <property type="nucleotide sequence ID" value="XM_003062839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N506"/>
    <dbReference type="STRING" id="564608.C1N506"/>
    <dbReference type="GeneID" id="9688527"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6601"/>
    <dbReference type="eggNOG" id="KOG0552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="77911at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009579">
        <property type="term" value="C:thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044208">
        <property type="entry name" value="FKBP19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47717">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP19, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47717:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP19, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="2">
        <location>
            <begin position="28"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="153" mass="16852" checksum="AAE8B2089AC437C1" modified="2009-05-26" version="1" fragment="single">EYPKYERTASGLLFQDLRYGEGDAVAPGRRVVVDWDGYTFYLSHVLQARNLPKGGDFEQNDDAFLSFIPGDGTVIPAFDECVKDMRVGGIRRFIVRPGPLSYPGVLKGNWKEGKDGVGPVPASLSGKRALEFVNRNTANVDKSLLFDVEILGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5J0</accession>
    <name>C1N5J0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_48778</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063372.1">
        <property type="nucleotide sequence ID" value="XM_003063326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5J0"/>
    <dbReference type="STRING" id="564608.C1N5J0"/>
    <dbReference type="GeneID" id="9688811"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48778"/>
    <dbReference type="OrthoDB" id="541985at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912309" evidence="3">
        <location>
            <begin position="26"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="613"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="475"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="659" mass="71035" checksum="73A0B67DDD90791D" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6H8</accession>
    <name>C1N6H8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PHOT</name>
        <name evidence="17" type="ORF">MICPUCDRAFT_49739</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063534.1">
        <property type="nucleotide sequence ID" value="XM_003063488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6H8"/>
    <dbReference type="STRING" id="564608.C1N6H8"/>
    <dbReference type="GeneID" id="9688782"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49739"/>
    <dbReference type="eggNOG" id="ENOG502QPPH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THVCLIS"/>
    <dbReference type="OrthoDB" id="432483at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009882">
        <property type="term" value="F:blue light photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd05574">
        <property type="entry name" value="STKc_phototropin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000294">
        <property type="entry name" value="Serine/threonine-protein kinase OXI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45637">
        <property type="entry name" value="FLIPPASE KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="17" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="15">
        <location>
            <begin position="32"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="16">
        <location>
            <begin position="106"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="15">
        <location>
            <begin position="217"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="16">
        <location>
            <begin position="291"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="437"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="347"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="606"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="798"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="606"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="647"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="810"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH52670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="819" mass="89166" checksum="3D1462E26D18D43A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6S1</accession>
    <name>C1N6S1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_7531</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063781.1">
        <property type="nucleotide sequence ID" value="XM_003063735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6S1"/>
    <dbReference type="GeneID" id="9689043"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7531"/>
    <dbReference type="eggNOG" id="ENOG502QPJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WESEDII"/>
    <dbReference type="OrthoDB" id="41501at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010865">
        <property type="entry name" value="DUF1499"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801:SF2">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07386">
        <property type="entry name" value="DUF1499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="134" mass="15391" checksum="F239A611AB701282" modified="2009-05-26" version="1" fragment="single">LGLCPPKPNCVSTAEDLNDDSHFVPSWTYNPEERARNPVSQKEAMAELLDVVNNTDCDGFEVNIVTKLDDYLYVEYKDPRLGFIDDVEFFFEPGEFSRVAYRTAGRVESPNNAKTQRARIKTLRLALEKKKWKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6Y0</accession>
    <name>C1N6Y0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_42971</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063632.1">
        <property type="nucleotide sequence ID" value="XM_003063586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6Y0"/>
    <dbReference type="STRING" id="564608.C1N6Y0"/>
    <dbReference type="GeneID" id="9689251"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42971"/>
    <dbReference type="OMA" id="CATECRE"/>
    <dbReference type="OrthoDB" id="3045089at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050498">
        <property type="entry name" value="Ycf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44858">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44858:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE SPINDLY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="102"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="175"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH52005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="416" mass="43860" checksum="BFE34D8BF3E3FFF3" modified="2009-05-26" version="1">MGCGASTPRSMLYPRAPRRRPVRRKPTKAELLKERADVNFFDASEAHHHGEHERALEQLTLALKLDPKHKRARLTRAEVCLALKKYDDALEDASQAIALGHPDAYRVRGDVHLARKRFRDALADLTIAVKVEPNDRRAWASRAAAHAGLGNDAKAKEDVAEAAKREAAKEDAGLCVVCIDEPRATRLNPCEHSALCEACATECRETLGCCPICNTMIKAIEYGMFMNTFAPTNTAALGGLASAIKRAREENAQMATLSRIGEGSPLMDESDDDGEITESSEGGSLVGVGVGDANANARAARGDDAAAAGRGDGGERAATPPPHRDYSQYTVGEDMRVESAPCTPAVLRGGLAAADGNGLSDLLAATPAAMGGEAVVEDAEDGEGEEEEEEDADGPTPLIGGVETITPQGTMLAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7F3</accession>
    <name>C1N7F3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65976</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063725.1">
        <property type="nucleotide sequence ID" value="XM_003063679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7F3"/>
    <dbReference type="GeneID" id="9689331"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65976"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="515" mass="53645" checksum="F6709ED05D252504" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7J0</accession>
    <name>C1N7J0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53713</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063741.1">
        <property type="nucleotide sequence ID" value="XM_003063695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7J0"/>
    <dbReference type="STRING" id="564608.C1N7J0"/>
    <dbReference type="GeneID" id="9689352"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53713"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="280" mass="30828" checksum="12CA468A353A3E39" modified="2009-05-26" version="1">MNLRSKLRRAEPSAPDLGDDSGRGAAARVAEATRTELERLKEELAAAKAKNAEYAEMYPTFNADEHVASVVFSHVTDVRTRVALAQVNTVWRAASKVASSLPASLDFTGCPDEKMGEGKYSCWTANCAYVVGIEGVLDLPETHFHGLLEQAGADFSRTADQCNLGVIYDCAERYDKALEWYMKGARQGCMFCESNIGMIYKHGDGVEKNIDTALEWFTKSAEKGNAIAQNSAGRILYDEGQYQDAFKWFTKSAAQGYTYAQSNLAKCYEDGKGVKKGLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7U4</accession>
    <name>C1N7U4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_49069</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:18945"/>
            <dbReference type="Rhea" id="RHEA-COMP:11676"/>
            <dbReference type="Rhea" id="RHEA-COMP:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:61965"/>
            <dbReference type="EC" id="1.14.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064151.1">
        <property type="nucleotide sequence ID" value="XM_003064105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7U4"/>
    <dbReference type="STRING" id="564608.C1N7U4"/>
    <dbReference type="GeneID" id="9689412"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49069"/>
    <dbReference type="eggNOG" id="KOG1591">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF246">
        <property type="entry name" value="TRANSMEMBRANE PROLYL 4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912423" evidence="12">
        <location>
            <begin position="22"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="13">
        <location>
            <begin position="293"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH51773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="433" mass="46660" checksum="399255B38104C3A4" modified="2009-05-26" version="1">MRAPLRVVLLLLLCVSTNARASSSDDDRARLVRAFQNALATHERGDASDALREYEAILADASARPHLSAKAEAILRTNAGGILYQRGNVDASRAHFKRATELDPSHAEARVNLANLLSEDVGSHEDALTHAREAVRLRPDHAKSHHLLGNVLQHLGQDIEAALRFKTAETLAAGDAAANAPAGIFQIRATEVGETKPWISPDGRELTVRTISVTPPVFRVEGFVTEREREAVIRKAAPEMRESRTVADGGKAGPTRRRKSETAWLVTHGDDALEALSTRATALLNLSADVAAAEERVQVLRYEKGGYFDVHHESTAFLRRFATVLYYLSGPGEGNGGHTAFPLGPHGEGTGEGTVVATAGNVTAACEGGVRAAPVPGDAIFFYNFGVNGRVDANAMHAACEVTGGTKWAANHWFNLAERRRRSPPPPPRDELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8B3</accession>
    <name>C1N8B3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heat shock protein 70kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HSP70G</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_30210</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064239.1">
        <property type="nucleotide sequence ID" value="XM_003064193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8B3"/>
    <dbReference type="STRING" id="564608.C1N8B3"/>
    <dbReference type="GeneID" id="9689680"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30210"/>
    <dbReference type="eggNOG" id="KOG0101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VCKPIVT"/>
    <dbReference type="OrthoDB" id="3789372at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000465">
        <property type="entry name" value="Heat shock cognate 70 kDa protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000016">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="622"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="519"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="622"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="656" mass="71635" checksum="49838638F771DFBE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8J3</accession>
    <name>C1N8J3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54107</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064276.1">
        <property type="nucleotide sequence ID" value="XM_003064230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8J3"/>
    <dbReference type="STRING" id="564608.C1N8J3"/>
    <dbReference type="GeneID" id="9689536"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54107"/>
    <dbReference type="eggNOG" id="KOG1716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043622">
        <property type="term" value="P:cortical microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035010">
        <property type="entry name" value="PHS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47100">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47100:SF5">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="439" mass="46247" checksum="A05DF44757ADB67F" modified="2009-05-26" version="1">MVASSSRPHAASASVSAAPPTHLSTFPPPSSAAVASRLAGGQRLSRDLRDAIEARWRHDAAATDEFARVFSETAARHGASSEARHRSSAQQPSSPTPPPPTPRARVDARASSSSSSSSSSPSSRPMATTPSHRKLRERLDACDVSGVDAASIDWSALASVISSEAVAALGARGRGEAEGDGDDDADARVAFEVNSGGAVFFCIFSSPPPPSSEPAPEPATERVLVVKFCSDRLAAQSEYFAHEIASALGVDVPETRLFRRKPAAAAAAAAANKESDARASSFDEWSAMTRAAERAVAEWRDDADAADADARDAAGRMLGCLRAQHAALVMRFVRGGGLFSTTRSRSPKGKVLKERRAPRERGRMGSSLNANADDAGDESSDRPLRPFDTPARSAAAAEALGRVFVLDVLLGNADRMKCERLAWRGAFYTLVPHTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8T7</accession>
    <name>C1N8T7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54235</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064506.1">
        <property type="nucleotide sequence ID" value="XM_003064460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8T7"/>
    <dbReference type="STRING" id="564608.C1N8T7"/>
    <dbReference type="GeneID" id="9689771"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54235"/>
    <dbReference type="eggNOG" id="ENOG502QPN1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VIPTHKA"/>
    <dbReference type="OrthoDB" id="498961at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34284">
        <property type="entry name" value="FG-GAP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34284:SF1">
        <property type="entry name" value="FG-GAP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="291" mass="29516" checksum="C5BF0A7FC94F4007" modified="2009-05-26" version="1">MSLPSPGLHADVNGDGVVDHVEVFGGGGGGAGRSHAAVGADGRAVPSCWARVTSGVPAREALFDGTACRGHAGVTRHGDRNSYGVDGAAGMFGGKNADVDVAPPAALRRGEETDVILFNSRGEVTSYGPDGKRRWQLRTDASWQRRDDVYDAGYGGGGGGGGGHLETFPLAVDGASEVVVALGAARGVVLSPGGYKIATLRLPSVPIAPVLIVDVNGDGLNDIVARTALGTYCWTQRGAGGGGPLLVLLGFLIVGMVVAFASQIGVGSDGKKVVRRSTEMDEPGGESAKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N943</accession>
    <name>C1N943_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54357</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064389.1">
        <property type="nucleotide sequence ID" value="XM_003064343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N943"/>
    <dbReference type="GeneID" id="9689994"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54357"/>
    <dbReference type="OrthoDB" id="2124888at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="303" mass="32182" checksum="38F5AAC93E04D546" modified="2009-05-26" version="1">MSTARRRASARPSTHPQSGAPSEILDDDAQEAVVVAVERDAARASALWRSAFGLAALVAGGYFAVLAARALGSRRVAIWRGVRRRVAVAVVAVVAPSRLASPTPPPPPPPPPPLLRSPCTRSSTAPSRRRSSPRWTARPRSSAFSPASRARGRSIDRRHVLLTLVPIRPRWRGERRSLRTMPGASLRTSLAFKPRPRCLSTPSDAFQLHPEKSDGKNDNDGVGPGTRPSSSATTERRRALAFSFALALAMCAGLAWVFAIERVGIAAAAKRAAAFGKRGAAAADADAKARPPHTGSHTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N968</accession>
    <name>C1N968_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_66592</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064401.1">
        <property type="nucleotide sequence ID" value="XM_003064355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N968"/>
    <dbReference type="STRING" id="564608.C1N968"/>
    <dbReference type="GeneID" id="9689842"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66592"/>
    <dbReference type="eggNOG" id="KOG1234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PEYYVPR"/>
    <dbReference type="OrthoDB" id="201153at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13970">
        <property type="entry name" value="ABC1_ADCK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034646">
        <property type="entry name" value="ADCK3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051409">
        <property type="entry name" value="Atypical_kinase_ADCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851:SF3">
        <property type="entry name" value="COENZYME Q8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="6">
        <location>
            <begin position="277"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="41"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="189"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="631"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="655" mass="69498" checksum="EC12879092091FF3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9A5</accession>
    <name>C1N9A5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_9279</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064419.1">
        <property type="nucleotide sequence ID" value="XM_003064373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9A5"/>
    <dbReference type="STRING" id="564608.C1N9A5"/>
    <dbReference type="GeneID" id="9689860"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9279"/>
    <dbReference type="eggNOG" id="ENOG502QQS3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GFTERIW"/>
    <dbReference type="OrthoDB" id="722566at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042651">
        <property type="term" value="C:thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010343">
        <property type="term" value="P:singlet oxygen-mediated programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044680">
        <property type="entry name" value="EX1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33917">
        <property type="entry name" value="PROTEIN EXECUTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33917:SF3">
        <property type="entry name" value="PROTEIN EXECUTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12014">
        <property type="entry name" value="Cyclin_D1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="105" mass="11170" checksum="0C91BEE350F65D20" modified="2009-05-26" version="1" fragment="single">VTAVKLTGDANVPAGAASFRARVGAEHRLESSFSYPDELGVVARYKGQGRVAKPGFTERIWVDGELLLLDGRGGSLTGGAELGFVWAVPGERRLLILFSSLELPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9J4</accession>
    <name>C1N9J4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein acetyllysine N-acetyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.286</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_4850</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the sirtuin family. Class IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="1"/>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064462.1">
        <property type="nucleotide sequence ID" value="XM_003064416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9J4"/>
    <dbReference type="STRING" id="564608.C1N9J4"/>
    <dbReference type="GeneID" id="9690072"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4850"/>
    <dbReference type="eggNOG" id="KOG1905">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000038">
        <property type="entry name" value="NAD-dependent protein deacetylase sirtuin-6 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF12">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="214" mass="23143" checksum="B80B1FA2B6F5836A" modified="2009-05-26" version="1" fragment="single">RALIELVKNARSRGGAIVHTGAGISTSTGIPDFRGPNGIWTAQRNGGAIPKASCAFFLARPSATHMALVALREAGYVRFLVSCNVDCLHLRSGYPRECLAELHGNCFAERCERCEREYVRDFEMPSVGFKRTGRACGEAGCGGRLRDQVLDWEDALPPKELKLAEKHSRDAPLALVLGSSLQITPSCDLPLKTVRAGGDLVIVNLQATPKDKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9K5</accession>
    <name>C1N9K5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable N-acetyltransferase 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_43375</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Probable acetyltransferase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the camello family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064467.1">
        <property type="nucleotide sequence ID" value="XM_003064421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9K5"/>
    <dbReference type="GeneID" id="9689751"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43375"/>
    <dbReference type="eggNOG" id="ENOG502S8XJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TTIVCMK"/>
    <dbReference type="OrthoDB" id="568204at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF51">
        <property type="entry name" value="N-ACETYLTRANSFERASE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="11">
        <location>
            <begin position="81"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH51372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="288" mass="30091" checksum="39BEE40A9029DEC3" modified="2009-05-26" version="1">MSAAFAMTPTARATPSPSLRASSIAARRAVVAPAAARRLAPSSSSRSSRATRVVATRAEYGDVERARGQDYNASANVFVDAFFLRGKPAGDNAITPSELSYLRGAQRKDLTRRYNRRGDAAMFVIRDDDGNGDVVGCVGAEVQRFQGIVPLSRADAETKGEVLDRPVIANLAVAASARRRGVAKRLMRAVEDEIRGWGYDEAVLVVESSNGKAKGLYGKLGYKVVGGEAATPNIVISEEGKVVNGAVRTSFMRKDLTKPDGGAGAPPAAVAVAVAVAVAVAAKVGGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9R0</accession>
    <name>C1N9R0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic</fullName>
            <ecNumber evidence="4">1.2.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GAPDH_4</name>
        <name evidence="13" type="ORF">MICPUCDRAFT_49771</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>D-glyceraldehyde 3-phosphate + phosphate + NADP(+) = (2R)-3-phospho-glyceroyl phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10296"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; Calvin cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.13" evidence="4"/>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064780.1">
        <property type="nucleotide sequence ID" value="XM_003064734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9R0"/>
    <dbReference type="SMR" id="C1N9R0"/>
    <dbReference type="STRING" id="564608.C1N9R0"/>
    <dbReference type="GeneID" id="9690221"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49771"/>
    <dbReference type="eggNOG" id="KOG0657">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTQVPID"/>
    <dbReference type="OrthoDB" id="1152826at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047100">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18126">
        <property type="entry name" value="GAPDH_I_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05214">
        <property type="entry name" value="GAPDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000002">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000001">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054835">
        <property type="entry name" value="G3PDH_Arsen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052978">
        <property type="entry name" value="GAP_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033735">
        <property type="entry name" value="G3PDH_Arsen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42955">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42955:SF1">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding" evidence="12">
        <location>
            <begin position="2"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="11"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="157"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="219"/>
            <end position="220"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="10">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00052787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH51114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="370" mass="40063" checksum="F832BEDA0C642D24" modified="2009-05-26" version="1">MVKVGINGFGRIGRLAFRLAYDNPALEFVHINEHPGAGESSAYLAKYDSVHGHWTHDCEYDAGKNAIVVDGTHEISYSAHDAPGDVPWEAHGVELVLECSGEFLTREKLAPYFARGVKKVLVSAPVKDASDPVLNIVYGVNHDKYDPAVDHIVTAASCTTNCLAPVVNVIQSKLGIVRGSITTIHNVTNTQTIVDAPNAKKSDLRRARSGLMILAPTSTGSATAIALIFPELKGKLNGLAVRVPLLNGSLTDCVFEVGRATTREEVNALIKDAAANEMCGVLGYEEKPLVSTDYINDTRSGIVDALSTMVVDGTHLKARSSVFTPVPVRPRSRCELHSLRTFSPGVCFSPPRVLRFQSRRTHLDAFQLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA57</accession>
    <name>C1NA57_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_54770</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064733.1">
        <property type="nucleotide sequence ID" value="XM_003064687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA57"/>
    <dbReference type="STRING" id="564608.C1NA57"/>
    <dbReference type="GeneID" id="9690174"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54770"/>
    <dbReference type="eggNOG" id="ENOG502QT6H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LYGEHHV"/>
    <dbReference type="OrthoDB" id="2020781at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.10">
        <property type="entry name" value="MurE/MurF, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051046">
        <property type="entry name" value="MurCDEF_CellWall_CoF430Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43024">
        <property type="entry name" value="UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43024:SF1">
        <property type="entry name" value="UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="MurE/MurF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur ligase central" evidence="5">
        <location>
            <begin position="188"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="455"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="487"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="624" mass="65644" checksum="732456F83280F2B9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA68</accession>
    <name>C1NA68_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_54781</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064854.1">
        <property type="nucleotide sequence ID" value="XM_003064808.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1NA68"/>
    <dbReference type="GeneID" id="9690181"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54781"/>
    <dbReference type="eggNOG" id="KOG0947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NDKGTHM"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="124"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="157"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="291"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="618"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="568"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="941"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1134"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1304"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1378"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="846"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1209"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="581"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="974"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1004"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1023"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1304"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1378"/>
            <end position="1389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH51188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1584" mass="169381" checksum="9C83B8752D378B20" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGV3</accession>
    <name>C1MGV3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49951</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054842.1">
        <property type="nucleotide sequence ID" value="XM_003054796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGV3"/>
    <dbReference type="GeneID" id="9680481"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49951"/>
    <dbReference type="eggNOG" id="ENOG502SA2A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2018625at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36809">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36809:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="419" mass="44810" checksum="4224281E3B80CF88" modified="2009-05-26" version="1">MPPTTLCGVCPPTRVARVARVGGASSASTPLAATSSTRVPISSSRRARRSRSSALPALPPDAIAAGFTDAAVDAVAAASAAATATDGASTFAASSMADALSDTGVPEWQIYYGAVAGLSPFVIAAYEFGKRILIQRRCELCQGSGLIKRGRYSRKCTSCGGFLPWESWELFFTSEAGNGGALRQPKGQTSAFYDVDAATEDSRRQAAAARAAADEEDEGAEESGAGVGAEERGGSTRLDAAPRHRACFSPRAVSGFRRRPRALATRARRSRRATPPPRAIGDGAAEAAEYRLATPEERATAEAIVVKPRMTHGLDVHRRIHVRAMRQLAYMSQWRAFCERAKLDPTSYASDDDEATLCSFHFELERGLDRFEEAKRANALDDYPPRTLHPTQGFPAIQAAFYAAVAEACGGQERLFDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGV4</accession>
    <name>C1MGV4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_7881</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054843.1">
        <property type="nucleotide sequence ID" value="XM_003054797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGV4"/>
    <dbReference type="STRING" id="564608.C1MGV4"/>
    <dbReference type="GeneID" id="9680781"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7881"/>
    <dbReference type="eggNOG" id="KOG3355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FALWMCQ"/>
    <dbReference type="OrthoDB" id="17199at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF0">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="107" mass="12313" checksum="8125C50D6CA690D8" modified="2009-05-26" version="1" fragment="single">GFVSREELGRATWLLLHTIAAEYPDEPTRAQRRDAREFLRTMTSLYPCERCGAEFADITRRDAPDVSSGDALRAWTCRAHNEVNAKLGKPAFACERFHERWRGVRCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH81</accession>
    <name>C1MH81_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_50082</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054907.1">
        <property type="nucleotide sequence ID" value="XM_003054861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH81"/>
    <dbReference type="STRING" id="564608.C1MH81"/>
    <dbReference type="GeneID" id="9680223"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50082"/>
    <dbReference type="eggNOG" id="KOG3144">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="17366at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009580">
        <property type="entry name" value="GPI_biosynthesis_protein_Pig-F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06699">
        <property type="entry name" value="PIG-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="65"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="378"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="393"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="409" mass="45379" checksum="D7CF634B4031B0A6" modified="2009-05-26" version="1">MSFGLDRTSVRLPFSLYTNPVFGSTSAMTGRWISSPARFSMARPAACAATRRLMVRRRSKTSIRRDVNFPSPPEMTTRRHSAARRGGARAMSESDDDDDDLPEEIITMNKNPSPYRLYLTLTTHPVRVPALVALAARALLVTAALYYSIALHCGETTNARPERGPPTGFWKDPLRATRCAIVTHHLVVLLTHALSSRYSNGDAPRAEAEHVPSRPSLLGSLWHSLVALAIGTAFWFVFMCNFGLSALYVPYPTTHASALLASLTFVPGAAMYGTSPWEGKGAQWEWHRVLVLGDGAFYPIDFQWFASAWGAALGAWMGAMPIPLDWGRAWQRWPITVVYGMCVGCVVGAWTGFAWAVAKWARGDRGVFGWGDGSYYARPAHDDDDGSREKEKRLRRNARLAKKRKEKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHM8</accession>
    <name>C1MHM8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_50257</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055519.1">
        <property type="nucleotide sequence ID" value="XM_003055473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHM8"/>
    <dbReference type="STRING" id="564608.C1MHM8"/>
    <dbReference type="GeneID" id="9680654"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50257"/>
    <dbReference type="eggNOG" id="KOG0120">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FLRIMQI"/>
    <dbReference type="OrthoDB" id="10266058at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="195"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="304"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="394" mass="42724" checksum="9ECFFF1FA612D681" modified="2009-05-26" version="1">MSGSPEVSSRVLLLPRSEVRLQRAILLGFLEGMGDERRHRRETSRDTSPRHRSRSGDDERGHRRETSRDTSPRHSRDGNGSRSQRRDGSPYRGRRFPSSPRHRGRHRSRSRSRDRKSGSESDDLGGYVPRIRRPSKHGITQPSSAPGASDAALNLVDPAERQRQAQQWILQQQAGSLARVQEASTVALGGPRKNREIFVGNIDAVVTKQALTALFDDALAVAFPNATSGDAKPVVNIQLGDQATYGFVELLSEELATAAIAGLNGLVFCGRPLTIARPTGWVDPAAAATITARAAAERGEEHSTIVCLSNIVTESDLADEEAYAELLADVRTECAKCGEVKDIRIPRGGPVGSVFVKMGDESGANKVQTEMAGRRFDGRAVVVSRVSSSAFDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHU2</accession>
    <name>C1MHU2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">E1 ubiquitin-activating enzyme</fullName>
            <ecNumber evidence="6">6.2.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_30909</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.45" evidence="6"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055551.1">
        <property type="nucleotide sequence ID" value="XM_003055505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHU2"/>
    <dbReference type="STRING" id="564608.C1MHU2"/>
    <dbReference type="GeneID" id="9681118"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30909"/>
    <dbReference type="eggNOG" id="KOG2012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CIREKCN"/>
    <dbReference type="OrthoDB" id="10252231at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004839">
        <property type="term" value="F:ubiquitin activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01491">
        <property type="entry name" value="Ube1_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01490">
        <property type="entry name" value="Ube1_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000015">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2660:FF:000002">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.60:FF:000001">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.180:FF:000001">
        <property type="entry name" value="ubiquitin-like modifier-activating enzyme 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.80:FF:000001">
        <property type="entry name" value="ubiquitin-like modifier-activating enzyme 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.180">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, FCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.80">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12550">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2660">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, SCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.60">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, UFD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042302">
        <property type="entry name" value="E1_FCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018965">
        <property type="entry name" value="Ub-activating_enz_E1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042449">
        <property type="entry name" value="Ub-E1_IAD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038252">
        <property type="entry name" value="UBA_E1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042063">
        <property type="entry name" value="Ubi_acti_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018075">
        <property type="entry name" value="UBQ-activ_enz_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01408">
        <property type="entry name" value="Ube1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF4">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09358">
        <property type="entry name" value="E1_UFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00985">
        <property type="entry name" value="UBA_e1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-activating enzyme E1 C-terminal" evidence="13">
        <location>
            <begin position="889"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="11">
        <location>
            <position position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH60803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1016" mass="110401" checksum="1A2C5EED2E9D0C31" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI96</accession>
    <name>C1MI96_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_50489</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055090.1">
        <property type="nucleotide sequence ID" value="XM_003055044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI96"/>
    <dbReference type="STRING" id="564608.C1MI96"/>
    <dbReference type="GeneID" id="9680272"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50489"/>
    <dbReference type="eggNOG" id="KOG4414">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TIVQPCK"/>
    <dbReference type="OrthoDB" id="5351233at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010387">
        <property type="term" value="P:COP9 signalosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033205">
        <property type="entry name" value="COP9_CSN8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13339">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13339:SF0">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="CSN8/PSMD8/EIF3K" evidence="6">
        <location>
            <begin position="49"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="209" mass="21740" checksum="C846A18765C22506" modified="2009-05-26" version="1">MATAVNERVDALLASGDAAAHCLVGATCDDAELACAGPIPEDWPRALQILGHLATGALVEAHLAWCRVPEPLRASDAELVAAKALLDALRRRDLAGLHARADGTSWSARAAPIVRAIASDARERALDLIARAYTTASVAHVAAALGTSAPDAIARCAARGWGVSEDGAWLDVVKPPVTEKQRAAIDALTSLTEVTTHLGDFALDTEQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIV4</accession>
    <name>C1MIV4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_50709</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ACBP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055199.1">
        <property type="nucleotide sequence ID" value="XM_003055153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIV4"/>
    <dbReference type="STRING" id="564608.C1MIV4"/>
    <dbReference type="GeneID" id="9681207"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50709"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0817">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AEMWISH"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF3">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACB" evidence="5">
        <location>
            <begin position="5"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="686" mass="72775" checksum="C676FC18C03DEBC8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIX9</accession>
    <name>C1MIX9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50736</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055212.1">
        <property type="nucleotide sequence ID" value="XM_003055166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIX9"/>
    <dbReference type="GeneID" id="9680363"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50736"/>
    <dbReference type="OMA" id="YWRAHVV"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="346" mass="36415" checksum="4F9A1B7088E810CE" modified="2009-05-26" version="1">MEPPSRAHTALWLLFIVPYAAFSAHAILALSLKRGVFGLVQGALLACVALPFWRAICRRPTYAPLSALLSRYRAKTPSSNAGFADASDAGLEWTRAIEAAVETFADELSSFARANAKTSLMNASSSAADSNSAMRDDGTGTGTPASPASPTSPTADEHPTRALLRSGWGVVPILDECSRPNALAAARFPRTSRAIAAANGFDAKFSTLAGRDVDVPRVGECDGYHRAHVVVLAEGGHERGAVVGVEVGGQRRTLRRGDVVVANDHLESRWFRPEGEDVDAACVLSFDVMKRAFRHCRAGVEKHRREHREALVGSGDGEGGASGGGVGAAVKRVAAAFARGFVGNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ59</accession>
    <name>C1MJ59_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_8507</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055776.1">
        <property type="nucleotide sequence ID" value="XM_003055730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ59"/>
    <dbReference type="STRING" id="564608.C1MJ59"/>
    <dbReference type="GeneID" id="9680791"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8507"/>
    <dbReference type="eggNOG" id="KOG0549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GDKWELV"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779:SF7">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="38"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH61028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="123" mass="13267" checksum="46C5A1EC4287E886" modified="2009-05-26" version="1" fragment="single">RAYLEANKLKDGVIETASGLQYRVLVEGAPGAPSPKANTPCSCHYRGTTIDGKEFDSSYSRGKPTTFAPNQVIAGWTEAMQLMTEGAKWELTIPSEIAYGDRQMGADITPGAVLVFTLEILKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJB0</accession>
    <name>C1MJB0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_50874</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Nibrin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055282.1">
        <property type="nucleotide sequence ID" value="XM_003055236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJB0"/>
    <dbReference type="GeneID" id="9680749"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50874"/>
    <dbReference type="OrthoDB" id="552194at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22667">
        <property type="entry name" value="FHA_NBN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040227">
        <property type="entry name" value="Nibrin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162:SF0">
        <property type="entry name" value="NIBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162">
        <property type="entry name" value="NIBRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="6">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="170" mass="18047" checksum="BD7C01749B0E925C" modified="2009-05-26" version="1">MPYRLDLHGGEGEEHHVVKSWTLIPGKYTVGRKDCTVTIADDPSISRVHAEIIVKKQKPDDAALAGTVPTVLVRDLGKFHTRVDGRKVGKSSPDGAVALPCAAGKSIATATLVFGCKTPTPTTATLTHVPIVLHVLGGEETRVENDEIVALAEETGFVLYTGSHTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJC5</accession>
    <name>C1MJC5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chloroplast envelope protein translocase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TOC34-1</name>
        <name evidence="5" type="ORF">MICPUCDRAFT_31209</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055808.1">
        <property type="nucleotide sequence ID" value="XM_003055762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJC5"/>
    <dbReference type="STRING" id="564608.C1MJC5"/>
    <dbReference type="GeneID" id="9680489"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31209"/>
    <dbReference type="eggNOG" id="ENOG502QSV2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QPREWTG"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006703">
        <property type="entry name" value="G_AIG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045058">
        <property type="entry name" value="GIMA/IAN/Toc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903">
        <property type="entry name" value="GTPASE, IMAP FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903:SF149">
        <property type="entry name" value="TRANSLOCASE OF CHLOROPLAST 33, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04548">
        <property type="entry name" value="AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51720">
        <property type="entry name" value="G_AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="5" id="KW-0946">Virion</keyword>
    <feature type="domain" description="AIG1-type G" evidence="4">
        <location>
            <begin position="57"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH61060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="321" mass="34063" checksum="F9B5F9182EB877D8" modified="2009-05-26" version="1">MTPAAAAAAAAAPPAAATAAAATPPTGPKEWTGLASMPQATQKSLVDVLNSLREKNQNEMTVVFVGKQGMGKSSTLNSVLNERVAVSAPFQPESLRPLLAGRAAAGFTLNLLDTPGLLEGDAVSARGVASVKLAMKDREVHAIVYMDRLDEWRVTNGDRAAFRALADAFGAEMWERTVIGLSHGQLSPPNGMPYDDFVAKRAAALRAAIRDELRSPGLALPHCVVENGSRCATNGGGEKVLPDADRTVWLTKFVSTLVDVAKSHEKPMAYDPEKVYSSAADPNKKRRWLVPILLALQTAVLRPLVVGTIRRDVKGGKAGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJE9</accession>
    <name>C1MJE9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">nicotinamidase</fullName>
            <ecNumber evidence="6">3.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Nicotinamide deamidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_11439</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; nicotinate biosynthesis; nicotinate from nicotinamide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.19" evidence="6"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055820.1">
        <property type="nucleotide sequence ID" value="XM_003055774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJE9"/>
    <dbReference type="STRING" id="564608.C1MJE9"/>
    <dbReference type="GeneID" id="9680501"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11439"/>
    <dbReference type="eggNOG" id="KOG4003">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DFVDSWP"/>
    <dbReference type="OrthoDB" id="167809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019363">
        <property type="term" value="P:pyridine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01011">
        <property type="entry name" value="nicotinamidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052347">
        <property type="entry name" value="Isochorismatase_Nicotinamidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008623">
        <property type="entry name" value="PRK11609.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080:SF2">
        <property type="entry name" value="LD05707P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080">
        <property type="entry name" value="PYRAZINAMIDASE/NICOTINAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="8">
        <location>
            <begin position="5"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH61072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="189" mass="20457" checksum="931FE017607DED56" modified="2009-05-26" version="1" fragment="single">GPSDALLVIDVQCDFCAGGALEVPGGDDVVPLCNALIRAFKRDRVVYSQDWHPPAHSSFASAHPGRAPFETIDAPYGAQTLWPDHCVRGTRGASFHPKLIVDWGEESEESGLGPWVVRKGFRPSVDSYSAFYENDRSTSTGLAEHLKSIGVRRVFVCGLALDYCVRFTALDARTAGFATVLVCDATRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJH4</accession>
    <name>C1MJH4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65213</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056621.1">
        <property type="nucleotide sequence ID" value="XM_003056575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJH4"/>
    <dbReference type="GeneID" id="9681861"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65213"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="239" mass="27230" checksum="F772E74A43C7F805" modified="2009-05-26" version="1">MTSCINFIVTLEPPTPPHALSRDITSHGRELASSTSRRAVAEFSRRESSAVPLSPVVAVAVILFAHTNPSHLLHRADRASARKPDDLHVQTPAAARCAQTTDFVQIRVLEPNARGGGRRGLAKRHQPVSRLERALDEHAVLVFDPHRPSREIVRGVRSKGRHDDGDRPFRVRRVRRIRRERHVELNLERFPPRADEPAPTETHVRPGTVPPRLRDRGSLRAAQRAPERRRRERRRVRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKB8</accession>
    <name>C1MKB8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cilia- and flagella-associated protein 206</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_55273</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CFAP206 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056360.1">
        <property type="nucleotide sequence ID" value="XM_003056314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKB8"/>
    <dbReference type="STRING" id="564608.C1MKB8"/>
    <dbReference type="GeneID" id="9681940"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55273"/>
    <dbReference type="eggNOG" id="ENOG502RRD5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QLMELMC"/>
    <dbReference type="OrthoDB" id="10251073at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003356">
        <property type="term" value="P:regulation of cilium beat frequency"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021897">
        <property type="entry name" value="FAP206"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21442">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21442:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12018">
        <property type="entry name" value="FAP206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="674" mass="73758" checksum="ABE87D32EE68486D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKD4</accession>
    <name>C1MKD4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_64323</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055976.1">
        <property type="nucleotide sequence ID" value="XM_003055930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKD4"/>
    <dbReference type="GeneID" id="9681328"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64323"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="70" mass="8071" checksum="F7F82C458B1C7507" modified="2009-05-26" version="1">MEHRLDSVIYHSSEFNTPGALNQAVPAHRSVVCKTDSALRNICRLLSSRTRRRNFMETVPNVKKLRDYIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKE0</accession>
    <name>C1MKE0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_49422</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in environmental stress response.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055980.1">
        <property type="nucleotide sequence ID" value="XM_003055934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKE0"/>
    <dbReference type="STRING" id="564608.C1MKE0"/>
    <dbReference type="GeneID" id="9681944"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49422"/>
    <dbReference type="eggNOG" id="KOG3173">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ANLCEAG"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050652">
        <property type="entry name" value="AN1_A20_ZnFinger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002653">
        <property type="entry name" value="Znf_A20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10634:SF149">
        <property type="entry name" value="AN1-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10634">
        <property type="entry name" value="AN1-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01754">
        <property type="entry name" value="zf-A20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00259">
        <property type="entry name" value="ZnF_A20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51036">
        <property type="entry name" value="ZF_A20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="A20-type" evidence="6">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="AN1-type" evidence="7">
        <location>
            <begin position="103"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="168" mass="18626" checksum="B5077F9A614C91AC" modified="2009-05-26" version="1">MAERARASEGDALSANLCEAGCGFFGNQNTANMCSVCYSLRTSCTGDNSEIRTNLDTSNSRIVQPIVTPILETDDDSELDKIDVGPFAVGEPEIKELNKRDEQCLLNRCYTCNKRTGFTGFRCRCEYIFCSSHRHSNKHNCTFDYKALGRDAVAKANPAVIAEKLHKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML31</accession>
    <name>C1ML31_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein MAK16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_49459</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the MAK16 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056488.1">
        <property type="nucleotide sequence ID" value="XM_003056442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML31"/>
    <dbReference type="STRING" id="564608.C1ML31"/>
    <dbReference type="GeneID" id="9681553"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49459"/>
    <dbReference type="eggNOG" id="KOG3064">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WHCIRHG"/>
    <dbReference type="OrthoDB" id="10251342at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.110:FF:000001">
        <property type="entry name" value="Protein MAK16 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006958">
        <property type="entry name" value="Mak16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405">
        <property type="entry name" value="MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405:SF4">
        <property type="entry name" value="PROTEIN MAK16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04874">
        <property type="entry name" value="Mak16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003352">
        <property type="entry name" value="MAK16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="5">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR003352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="218" mass="25450" checksum="16053947D9409DC7" modified="2009-05-26" version="1">MQSDEVIWQVIVNQGQCSYKVVTGNETFCRNKYNVTSLCNRSSCPLANSRYATVVEEGGAAFLCMKTVERAHTPATLWHRVRLDKNYSTALKQIDVQLTHWSKFLVHKSKQRLTKISQFLMRTRKLMQRRRPKQRTLPARQLKREAKRESKAQLAAQLEKTIEMELLDRLRSGTYDVLEPQEVKNVTENVRPNMNDLTGEKQRKHLELEYEGVNEVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML37</accession>
    <name>C1ML37_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_64797</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056105.1">
        <property type="nucleotide sequence ID" value="XM_003056059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML37"/>
    <dbReference type="GeneID" id="9682001"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64797"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="50" mass="5492" checksum="7BCE63641C92D42D" modified="2009-05-26" version="1">MLFYKSTRSCQSMLCSCDSDTNAVDPRASRVMSSNMPCSHRAKNGVCAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML97</accession>
    <name>C1ML97_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_25166</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056135.1">
        <property type="nucleotide sequence ID" value="XM_003056089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML97"/>
    <dbReference type="STRING" id="564608.C1ML97"/>
    <dbReference type="GeneID" id="9682014"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25166"/>
    <dbReference type="eggNOG" id="KOG2018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GSWVVTM"/>
    <dbReference type="OrthoDB" id="10265862at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061503">
        <property type="term" value="F:tRNA threonylcarbamoyladenosine dehydratase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061504">
        <property type="term" value="P:cyclic threonylcarbamoyladenosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00755">
        <property type="entry name" value="YgdL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="2">
        <location>
            <begin position="56"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="472" mass="52692" checksum="DB7D446D2A8A88DA" modified="2009-05-26" version="1">MITMRLFEAFMAGSTVGAVLVSILYSRRHQVPSRVFTGKLFHTSSATDEILAEHFTRNVQFFGSTAQQRVSSVFVVVVGLGGVGSHCAHMLLRSGVSRMRLIDFDQISLSSLNRHALGTRQDVGSYKAECLAKHFRKIFPEAQLETKVAMFEKTVEDELLKGEPDFVVDCIDNVDTKVDLLAACVRKNINVLASGGAGAKCDPTRIKIVDIRESVVDPLARAVRHRLKQVHGIESGIPVLLSTEKQRCKLVSLGATAETCSASILQDFQVLPNFRIRTLPVFGALPAIFGLSCAAHVISTLTGQVLSSDPILHIHTKQYKTQFERLRDREASRGSMKSWVNVELQDVIYLIKDVWQGRSARAQNPSIGKGMWRNTSDLCLTRWNPSKPANLDNLILLSSEEADAHDAEVFRIFETDNDSDQIKPCGFDSLVDREPYFAYFIERKLQRVRRDFGLVRESPNTCSGLNIHLMEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLT8</accession>
    <name>C1MLT8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_62254</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057278.1">
        <property type="nucleotide sequence ID" value="XM_003057232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLT8"/>
    <dbReference type="GeneID" id="9682260"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62254"/>
    <dbReference type="OMA" id="GECESKM"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002911990" evidence="1">
        <location>
            <begin position="23"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="236" mass="24986" checksum="DB69EFE7549FE55A" modified="2009-05-26" version="1">MPSSSTSLLGFVALTLVASASAARPGSTTAILEPATGLAGKEFASTTESTTTPTIQTTARLPASLGGVSALGLSPTCSQSYDTLNQNRAYTDAANDVYQVTREVGQEAGGECESKMQPSANPLGGWCHVDAMKYWTQDETKMAVLPPMRRAADAALPEDERGTVIWLDEDFITKSPTSWLPMLGSEFILKGIMPIYIPGPCVNEADVNGVLGYYGAGCKTEENFASCKFTRHGADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM21</accession>
    <name>C1MM21_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Elongation factor Tu</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_32374</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056863.1">
        <property type="nucleotide sequence ID" value="XM_003056817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM21"/>
    <dbReference type="STRING" id="564608.C1MM21"/>
    <dbReference type="GeneID" id="9682758"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32374"/>
    <dbReference type="eggNOG" id="KOG0460">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EGDKEWG"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03707">
        <property type="entry name" value="EFTU_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000001">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000003">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF22">
        <property type="entry name" value="ELONGATION FACTOR TU, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="49"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="435" mass="47262" checksum="69A1106501B23C0A" modified="2009-05-26" version="1">MAFRKLAARAAQVAARPYVSARVSALYPRQAPPALWTSSRAYDVNTRSKEHLNIGTIGHVDHGKTTLTAAITKVLAEVGGATSVAFDQIDKAPEEKARGITISTAHVEYETEKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLARQVGVPNLVVFLNKVDTVDDSELIDLVEMELREMLSFYKFDGENIPIIRGSALHALKGTDDKLGKDAIMALMKACDESIAAPKRALDKPFSMPVEDVFSIQGRGTVATGRIEQGIVKSGEEVELVGIVPTQKTTITGVEMFKKSLNEGQAGDNCGLLLRSLKRDQVQRGQVLCKPGTITPHKKFEAEIYVLNKDEGGRHTPFFSNYRPQFFMRTADITGTITLPEGVEMVLPGDNVNAVFELITPIALEKGMRFALREGGRTVGAGVVAKVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MME9</accession>
    <name>C1MME9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_46786</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056917.1">
        <property type="nucleotide sequence ID" value="XM_003056871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MME9"/>
    <dbReference type="STRING" id="564608.C1MME9"/>
    <dbReference type="MEROPS" id="M16.A03"/>
    <dbReference type="GeneID" id="9682832"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46786"/>
    <dbReference type="eggNOG" id="KOG0959">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PMSGRIH"/>
    <dbReference type="OrthoDB" id="10251424at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050626">
        <property type="entry name" value="Peptidase_M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690">
        <property type="entry name" value="NARDILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690:SF34">
        <property type="entry name" value="ZINC PROTEASE PQQL-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="9">
        <location>
            <begin position="90"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="10">
        <location>
            <begin position="246"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="10">
        <location>
            <begin position="743"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH58562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1059" mass="117427" checksum="771C250650EDBC55" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN01</accession>
    <name>C1MN01_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46861</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057015.1">
        <property type="nucleotide sequence ID" value="XM_003056969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN01"/>
    <dbReference type="STRING" id="564608.C1MN01"/>
    <dbReference type="GeneID" id="9682454"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46861"/>
    <dbReference type="OMA" id="CFRMREG"/>
    <dbReference type="OrthoDB" id="495655at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="615" mass="69322" checksum="30D886E66544E9D0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN24</accession>
    <name>C1MN24_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA topoisomerase 2</fullName>
            <ecNumber evidence="13">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_46870</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the type II topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="13"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057506.1">
        <property type="nucleotide sequence ID" value="XM_003057460.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MN24"/>
    <dbReference type="GeneID" id="9682468"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46870"/>
    <dbReference type="eggNOG" id="KOG0355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TWTQDFK"/>
    <dbReference type="OrthoDB" id="276498at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000819">
        <property type="term" value="P:sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16930">
        <property type="entry name" value="HATPase_TopII-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03481">
        <property type="entry name" value="TopoIIA_Trans_ScTopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03365">
        <property type="entry name" value="TOPRIM_TopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000003">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.30:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000008">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000004">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.670:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.199.10:FF:000002">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050634">
        <property type="entry name" value="DNA_Topoisomerase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001154">
        <property type="entry name" value="TopoII_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031660">
        <property type="entry name" value="TOPRIM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034157">
        <property type="entry name" value="TOPRIM_TopoII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169:SF38">
        <property type="entry name" value="DNA TOPOISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169">
        <property type="entry name" value="DNA TOPOISOMERASE/GYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16898">
        <property type="entry name" value="TOPRIM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01158">
        <property type="entry name" value="TOPISMRASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11 12 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12 13" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="15">
        <location>
            <begin position="478"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="16">
        <location>
            <begin position="726"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1204"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1289"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1210"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1229"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1302"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1332"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1378"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1414"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1438"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1452"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="12">
        <location>
            <position position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH59151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1473" mass="162897" checksum="92FD9DACB43A332D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNE5</accession>
    <name>C1MNE5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Triosephosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_46562</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056637.1">
        <property type="nucleotide sequence ID" value="XM_003056591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNE5"/>
    <dbReference type="STRING" id="564608.C1MNE5"/>
    <dbReference type="GeneID" id="9682530"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46562"/>
    <dbReference type="eggNOG" id="KOG1643">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IEKNGTM"/>
    <dbReference type="OrthoDB" id="6715177at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000025">
        <property type="entry name" value="Triosephosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="318" mass="33441" checksum="53C0F0A2D47C1945" modified="2009-05-26" version="1">MSVVASTAASVVAPAAPSFVGLRRVKGPGALSRDVEAHPSVTLATSVRGARASRGASSRCVATMAGTGKFVVGGNWKCNGNTASITQLVKDLNKGEIDADVDVIVAPPMLYLPKVQSTIDRQFKLSAQNCWVSEGGAFTGEVSAEMLADANVPWVILGHSERRALCGESDEFVGKKVAYAIKNGLSVMACIGETLQERESGATQDVCRRQLQAIVNELSAGDWEKVVIAYEPVWAIGTGKVATPEQAQETHAGIRAFMASAVSQDVASKVRIQYGGSVNGQLQELAKQEDIDGFLVGGASLIGDAFITICNSAKYNTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNR5</accession>
    <name>C1MNR5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56001</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057155.1">
        <property type="nucleotide sequence ID" value="XM_003057109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNR5"/>
    <dbReference type="STRING" id="564608.C1MNR5"/>
    <dbReference type="GeneID" id="9682123"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56001"/>
    <dbReference type="eggNOG" id="ENOG502S4FM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LYWLAPH"/>
    <dbReference type="OrthoDB" id="535128at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051703">
        <property type="entry name" value="NF-kappa-B_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46609">
        <property type="entry name" value="EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46609:SF6">
        <property type="entry name" value="EXONUCLEASE, PHAGE-TYPE_RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="522" mass="55762" checksum="35DB68D7B03F55CF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP86</accession>
    <name>C1MP86_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56183</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056777.1">
        <property type="nucleotide sequence ID" value="XM_003056731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP86"/>
    <dbReference type="STRING" id="564608.C1MP86"/>
    <dbReference type="GeneID" id="9682681"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56183"/>
    <dbReference type="eggNOG" id="KOG0546">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QHDTLKR"/>
    <dbReference type="OrthoDB" id="408413at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="3">
        <location>
            <begin position="66"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="332" mass="35191" checksum="7EF5A7A213F7116B" modified="2009-05-26" version="1">MTKFDNVAISHRKKSKGESYTAAELRRNMMEFQRTGVHPELKAREESNTDASSSLPMHNPGRAHAFMDIAVGKDPIGTLVIEVFDDIAPNAAREFILRVSDDGGAGRAGDVKYANTEIHMIADGVNIDGGRAPGMKPPTGGGGVPIEEAKTLTHCEAGVVSLKRDSPEYTIALHHCHHLDGARQVVGRVVKGLDHLSTLSEIEVDDQWEPMRKVMVTTCGVTTWAAADGGTLSLAAETRAANAAAAAARAAKERGESKEETKKRLDMESAALGAGLKRSLADGIAAAAEAERKRAKVDAAAAPKPVWRGGMMDAMLGELSDSDGDDSDGDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPE8</accession>
    <name>C1MPE8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-ascorbate peroxidase</fullName>
            <ecNumber evidence="3">1.11.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_8305</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.11" evidence="3"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057562.1">
        <property type="nucleotide sequence ID" value="XM_003057516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPE8"/>
    <dbReference type="STRING" id="564608.C1MPE8"/>
    <dbReference type="GeneID" id="9683386"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8305"/>
    <dbReference type="OMA" id="YVFDNEY"/>
    <dbReference type="OrthoDB" id="2859658at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016688">
        <property type="term" value="F:L-ascorbate peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00314">
        <property type="entry name" value="plant_peroxidase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF8">
        <property type="entry name" value="L-ASCORBATE PEROXIDASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH57513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="170" mass="18338" checksum="79922B97984C9D7E" modified="2009-05-26" version="1" fragment="single">VVKTKAPAVLRLVFHDAGTYRRGLGPVLATMDALRDTPAAAASLADVIAAAGAYAVELTGGPIIRVRLGRVDAVSADPENRMPADTLTGEEQRAHFVRAGFSTREMVAIAGAHTIGGKGFGEPYVFDNEYYKTLLARPLEYVRKYAEDQGLFFEDFGAAYLKLTEQGATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPF9</accession>
    <name>C1MPF9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_39105</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPP4R2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057569.1">
        <property type="nucleotide sequence ID" value="XM_003057523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPF9"/>
    <dbReference type="STRING" id="564608.C1MPF9"/>
    <dbReference type="GeneID" id="9683048"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39105"/>
    <dbReference type="eggNOG" id="KOG3175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DEVHTEN"/>
    <dbReference type="OrthoDB" id="341898at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015267">
        <property type="entry name" value="PPP4R2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487">
        <property type="entry name" value="PPP4R2-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09184">
        <property type="entry name" value="PPP4R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="302" mass="31418" checksum="71C029C1D297D646" modified="2009-05-26" version="1">MAGTPAHVEALEAFARLDERERVADGLVLDVVREIADTARVRHEWRLVSPAVASLLRASLLEHAKRDDDASAKAATATRQNEEGDEANEDDDAVVVGPPRPPAASREDDVEDILGSLAAFRRDPPFTIQRVCELALDPRAYYATFDKLKHAMEKLLMVTGTVENGLGDAVDAGGRRDGDREEDTRAAKRHKADPANAEQSAFVSSLIASRATTAAAAAAVAAAAAASGVGGGGGGAGTERAMEDLTSREEKNPRETTAREFENASAAAAADATAGDDGADAAEAARAAEAMSTSPKAGMVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPK1</accession>
    <name>C1MPK1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_16149</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057593.1">
        <property type="nucleotide sequence ID" value="XM_003057547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPK1"/>
    <dbReference type="STRING" id="564608.C1MPK1"/>
    <dbReference type="GeneID" id="9683100"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16149"/>
    <dbReference type="eggNOG" id="KOG0032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RTEWRNG"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="320"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="356"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="397"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="438"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH57544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="500" mass="55440" checksum="8F1C09B3CA5F7BEC" modified="2009-05-26" version="1" fragment="single">IGAGSYGIVRKVTRRSDGKKFALKTIRKAPWRQPPTSRTSVQYYHSKLRNELEVMRKIGSSLSIVYLYDSFEDGDAVHLLMDLCTGGELLGRMRAGINYSERDAAELVRSVVRTAAQCHSRGIIFRDIKPDNFLFDNEALDSPLKATDFGLAGLITPGEKLTRRCGTPSYMAPEVINRNYGEEADVWSCGVVAYQLLTGRLPFVDKVNQRPNAKEVFRAILEDQIDFVADPWPRLSPECVDLVRKMLDRDPETRITARAALLHPWLLAPTSEEALSGATQPIGGQVVARLQRFSTYGLLKRSVLRLLGDQLRKDDPNAGPGVEGFLELFQLLDTSGDDLVEPDELQAGLMRVGYDITQDECEQLLDSLDTTNDGCIDVDEFLAALVDWEALERSSEAYPSWVKEAFNMLDKDGNGTIDAGEVAELVFMNEDDGKLTSEAKKVIAACISEADTDGDGLIDLDEFITLLQMDPTDRLDAYELRLSKRGGSVDLSADETVLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPK7</accession>
    <name>C1MPK7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_56942</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057597.1">
        <property type="nucleotide sequence ID" value="XM_003057551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPK7"/>
    <dbReference type="STRING" id="564608.C1MPK7"/>
    <dbReference type="GeneID" id="9683410"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56942"/>
    <dbReference type="eggNOG" id="KOG1161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4580">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PVLRTQC"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="803"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="851"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="domain" description="VTC" evidence="8">
        <location>
            <begin position="237"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="7">
        <location>
            <begin position="719"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="269"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="589"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="647"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="682"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="759"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="589"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="759"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="874" mass="92846" checksum="DB95AF1AF6147D38" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPQ9</accession>
    <name>C1MPQ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytidine/deoxycytidylate deaminase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_26164</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057995.1">
        <property type="nucleotide sequence ID" value="XM_003057949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPQ9"/>
    <dbReference type="STRING" id="564608.C1MPQ9"/>
    <dbReference type="GeneID" id="9683115"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26164"/>
    <dbReference type="eggNOG" id="KOG1018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VCENECK"/>
    <dbReference type="OrthoDB" id="408702at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF179">
        <property type="entry name" value="TRNA(ADENINE(34)) DEAMINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="201" mass="21437" checksum="CFCF352D42E400C7" modified="2009-05-26" version="1">MSLAIEEAKLASRRLEVPVGAVLVRASTGEVLASHHNTVDEEDDPTAHAELKCIRDGAKRLGGWRYLAETTLYVTLEPCPMCAGAVLNARLGEVVWGAPNPLIGGDGSWLPIMGDGGGADVAEADVDEPEDAVRSCSIPGGGGPVRPHAFKPTLVVRRRVLEEECAALMRSFFRERRDASKAAREVARAEAEDADPPRTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPX4</accession>
    <name>C1MPX4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrolase, alpha/beta fold family-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_70909</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058024.1">
        <property type="nucleotide sequence ID" value="XM_003057978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPX4"/>
    <dbReference type="STRING" id="564608.C1MPX4"/>
    <dbReference type="GeneID" id="9683073"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70909"/>
    <dbReference type="eggNOG" id="KOG1454">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ASTDHWR"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46438">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46438:SF2">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="45"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="330" mass="36482" checksum="7E8F53BDBFD7C949" modified="2009-05-26" version="1">MPPLENDAKGVERLQLREDGWKFWRWRDHRCHYISAGEDNDGPIVVLVHGFGAHSYHWRYTIPALARKGFRVYALCMLGYGWSPKVEEPYSMEQYWGTQVIDFARDVAGATEKDKCVVAGNSIGALAALYAASRAPDQTRGLCLVNSAGNFEEGAAPGPEKKTLAQRAVGSDKGDAIRDPTDINAPPMSVKERLQEIFGRFVATGIFYFTKVRIKTILNQVYEFPVDDDLVRSIELAAEDPGAIGTFYQLSLAGGRTKVAAGELLDNYKGPLMLLWGETDPWMTPTKAERIMQMKPDAVYAPVLAGHCPHDDAPVECSEKLADWAMGLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQU5</accession>
    <name>C1MQU5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57416</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057817.1">
        <property type="nucleotide sequence ID" value="XM_003057771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQU5"/>
    <dbReference type="GeneID" id="9683628"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57416"/>
    <dbReference type="OMA" id="YVWEDSE"/>
    <dbReference type="OrthoDB" id="10573794at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="10"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="200" mass="22809" checksum="DDA35CB7B4E93CE2" modified="2009-05-26" version="1">MTADAEKKVITINVKLLPKYHSDHAQLTRYQLGHRKDYVGKLTRVKCSPSDTIKELKAQIEKERGSPVQYVKRGGTPTGVILSDDATLESLGLDYDMSVYEHLWEDSDENQEKFVVDREKVREMVGMFMMEHPDIGRHGPEVTGEAEDPKDWTAKNLKKRENMEKEVQKERERKQKRREEEAAKATAAAKAAKEGKPVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQZ6</accession>
    <name>C1MQZ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_39441</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057840.1">
        <property type="nucleotide sequence ID" value="XM_003057794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQZ6"/>
    <dbReference type="GeneID" id="9683656"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39441"/>
    <dbReference type="OMA" id="HNSENEM"/>
    <dbReference type="OrthoDB" id="10521218at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="70"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="480" mass="52128" checksum="007A195DDB514CF8" modified="2009-05-26" version="1">MKFPSMEDDNLMQSVSEVDDFVLQEFLADAADWSGSGAPSSVSPDSFAGTNVAAAPPPMPAGSGGGPADTAEQRRKRQREANLQAQRRSRERHRKHVSHLEADVVALRVELDASKAENARLQTALQQSLLGLEECQKRFSGSHQALGELSKEKEATKQKLEETLEKLRICAGVCEDLRGRLQNGEAAKMEIVKREPGDCAPCDELEARMKIEIANGAPPSGQSLQADAKRWLSVATIAKKTCEREKTCKNREEVMAGLKRVGLRLQEAFRSYLIDGNACSNIGVFAIKPVKPGEPSPCAAMAARGPGQDERVFQRAREIASELDLSDQQREDVVTHWKEHAKNLTALFEQRKKLTADALVLQGSSPVATLIDFLSIGTGLLSTDDEAAVVDRGGQQSLTGFAQHACKVEGVINALRQSIGAEQMLNFSLVSTVVTKVLTPLQTCFVCASWDSDGCPDMLAISRAITVQSMEKLPHLQGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR96</accession>
    <name>C1MR96_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Dead-box like helicase with PHD domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_57576</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057894.1">
        <property type="nucleotide sequence ID" value="XM_003057848.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MR96"/>
    <dbReference type="GeneID" id="9683702"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57576"/>
    <dbReference type="eggNOG" id="KOG0354">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CNDCPRM"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18033">
        <property type="entry name" value="DEXDc_FANCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12091">
        <property type="entry name" value="FANCM_ID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15568">
        <property type="entry name" value="PHD5_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000861">
        <property type="entry name" value="Fanconi anemia, complementation group M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1320.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039686">
        <property type="entry name" value="FANCM/Mph1-like_ID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044749">
        <property type="entry name" value="FANCM_DEXDc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025">
        <property type="entry name" value="FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="FANCONI ANEMIA GROUP M PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="343"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="689"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="13">
        <location>
            <begin position="1778"/>
            <end position="1823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="24"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="200"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="789"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="937"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1059"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1220"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1713"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="102"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="276"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="794"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1059"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1237"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1255"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1288"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1314"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1361"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1375"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1429"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1446"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1497"/>
            <end position="1517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="1545"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1576"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1647"/>
            <end position="1666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1720"/>
            <end position="1729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH57845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1823" mass="191649" checksum="177AE9F0599D5C0C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRD2</accession>
    <name>C1MRD2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_7249</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058286.1">
        <property type="nucleotide sequence ID" value="XM_003058240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRD2"/>
    <dbReference type="GeneID" id="9683346"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7249"/>
    <dbReference type="eggNOG" id="KOG4474">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CEMASPK"/>
    <dbReference type="OrthoDB" id="506011at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042512">
        <property type="entry name" value="TLCD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31898:SF1">
        <property type="entry name" value="TLC DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31898">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="17"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="180" mass="19704" checksum="6DA9E588F1152DA7" modified="2009-05-26" version="1" fragment="single">LGWGLMFLLFRVGVFRKYSADFSNRVVSIIHAIVAVYYAYLTFTNGWAGMFDDIGGANTPAQALCMAISLSYFVYDLIYCAVVGELESVFHHMFTIGGLASGVFEGKSGSELVACLFLMEVSNPSLHLRTVLAEMGLKNSALASMNNLIFALVFLVCRLVIGPPLVYKTMVCPDNAYIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRS7</accession>
    <name>C1MRS7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_17207</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058562.1">
        <property type="nucleotide sequence ID" value="XM_003058516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRS7"/>
    <dbReference type="STRING" id="564608.C1MRS7"/>
    <dbReference type="GeneID" id="9684001"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17207"/>
    <dbReference type="eggNOG" id="ENOG502S9WY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QVMWKYL"/>
    <dbReference type="OrthoDB" id="5234at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.40">
        <property type="entry name" value="Protein of unknown function DUF3067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021420">
        <property type="entry name" value="DUF3067"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35126:SF1">
        <property type="entry name" value="DUF3067 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35126">
        <property type="entry name" value="SLR0598 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11267">
        <property type="entry name" value="DUF3067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="106" mass="12399" checksum="A4D6B3C940F0A188" modified="2009-05-26" version="1">MTGEELRMLVLNKWGKMYDTRIHQRRDQFNKLGLYLQIMWKHVGQKSFPMTEQQYVEQLSAVAELLTEWGAQDVVRQKLPQSTKFPKMDTTGANAVMIPLDIELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRZ6</accession>
    <name>C1MRZ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_58288</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058962.1">
        <property type="nucleotide sequence ID" value="XM_003058916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRZ6"/>
    <dbReference type="GeneID" id="9684401"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58288"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="107" mass="11916" checksum="920B5563EBE15260" modified="2009-05-26" version="1">MALSAGPDPAPFFESRRRLTYFLDAPVRYLSLCQRWLTPFPNGRLVTVVGDAIDVSEGAEYAKGGKVESPSREEVRKAHARYCDALLKLIEETKAEAGYPTQRTVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS23</accession>
    <name>C1MS23_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68346</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058611.1">
        <property type="nucleotide sequence ID" value="XM_003058565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS23"/>
    <dbReference type="GeneID" id="9684411"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68346"/>
    <dbReference type="OrthoDB" id="275278at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="259" mass="27534" checksum="A27A4366A77D2475" modified="2009-05-26" version="1">MDAKLVSAVDRGAPDLIDDDALTELATDIPDLKSRLGIADERARSSCREACGCCSTTSGRLSVLRQGGDRKHAAAAGGADDSPDDAGHLHVRAVRDHPDHSADSRRARAHILVHSEVLPRVVSVAVFAAAAGAHEEVRGPATAAERGGEEQGDAQEDEALKGGQRGREPHGRRRERGGARRRARGSRRGGRQEGEGAKPLRAEGASTHGVGGRGKHRGAQVARRDRVAVADRGRGRRRRRGDGVAMMNARPTPSRSRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS67</accession>
    <name>C1MS67_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58367</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058994.1">
        <property type="nucleotide sequence ID" value="XM_003058948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS67"/>
    <dbReference type="GeneID" id="9684433"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58367"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="494"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="536" mass="55776" checksum="C80382EBB0849E80" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT49</accession>
    <name>C1MT49_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate-binding module family 20 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GWD3-B</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_57937</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058801.1">
        <property type="nucleotide sequence ID" value="XM_003058755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT49"/>
    <dbReference type="STRING" id="564608.C1MT49"/>
    <dbReference type="GeneID" id="9684240"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57937"/>
    <dbReference type="OMA" id="TERAMTR"/>
    <dbReference type="OrthoDB" id="512712at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05467">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM20" evidence="2">
        <location>
            <begin position="65"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="685" mass="72292" checksum="343AEDBFE50163AC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTS3</accession>
    <name>C1MTS3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_49611</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059368.1">
        <property type="nucleotide sequence ID" value="XM_003059322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTS3"/>
    <dbReference type="GeneID" id="9684530"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49611"/>
    <dbReference type="OMA" id="QLRMTWS"/>
    <dbReference type="OrthoDB" id="494972at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="263" mass="27317" checksum="058F34E9127DA33D" modified="2009-05-26" version="1">MDQMDVSLAGRINVRGDGNVVEDRFSLTASADFAKGGRITLNANPGFRPSAALKDGKTNLTDASQLSGIGNLDDIDVSISKSADILGQACDLTLSTESLGNGGIAGLQVKTNVDKVGDVTLTLAKKGHKAFSGKSKDGEAQASENDACRIDVALPLSDVNADLTGSVNYDLNTQDANLSLGYKNGDVALRLRTSMGSDKSLSHKVNADYSGIEGIGLGLEVNDAGAGKVTVTKDKYSLVVPVSKDGGVDTNNASLRMTWSMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTZ2</accession>
    <name>C1MTZ2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58609</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059406.1">
        <property type="nucleotide sequence ID" value="XM_003059360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTZ2"/>
    <dbReference type="STRING" id="564608.C1MTZ2"/>
    <dbReference type="GeneID" id="9684513"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58609"/>
    <dbReference type="eggNOG" id="ENOG502SDR8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MVGWWSL"/>
    <dbReference type="OrthoDB" id="542523at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="143" mass="15193" checksum="080A1B306C955533" modified="2009-05-26" version="1">MLATANVNAVAASATRPASLSARRGLVAASPLRVAKTAPRARVVRMSARAEEGVFDKIKRLIAENDEKERKKKIVASPTGVPPPPVVPVLEPGKIGFVANAEMWNSRASMVGWWSLLLVEAVAGKGLLEIMGFSVGKGINFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUI3</accession>
    <name>C1MUI3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_69576</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059498.1">
        <property type="nucleotide sequence ID" value="XM_003059452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUI3"/>
    <dbReference type="STRING" id="564608.C1MUI3"/>
    <dbReference type="GeneID" id="9684644"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69576"/>
    <dbReference type="OMA" id="ARCKERI"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="459"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="167"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="499" mass="55058" checksum="C8FF3FF554478104" modified="2009-05-26" version="1">MATVCEATLDSPYSKKDGGGGECGVSGGVSKRDGEEAAPPRSLTSPLRAKIESDNAFGGSPELPPIVRALAEDAKGMRARLKRYRDERDRGEKTLIAQRVLCAKLQDKIIALESALAKFVNGATRETALRELRKARTACELIDAAEAKATDASKRATIERKSKEADSKKHRRAMLLLEREREDERREHEKTRAALFDKDREARAFALRIRTLAKKLKDANDAVAAATLQKDTLEGRCTTPGTAEDVVELEVEAPVDAPEAVPEEEEEEAPLALEAVASPAAVPAPPQTQTPPIVVNIVIEPVERAHVMLCLIHDDAPATRIESESPLAPPPPAALIAEDEKEDETPPSPPPPDETETTAADRHRRDPAAESPRVREQTPAAARGRRRDRALARETETDRAEEARLGAEKRRLELERRRGAAVQVRRRESAAAPRRRGREDVEGVKGAKRNKARGTLSRVQIIYCIVVVLLPVFYIHRRRERRRAPFARAVPFVRSRATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUM5</accession>
    <name>C1MUM5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_18054</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059222.1">
        <property type="nucleotide sequence ID" value="XM_003059176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUM5"/>
    <dbReference type="STRING" id="564608.C1MUM5"/>
    <dbReference type="GeneID" id="9684962"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18054"/>
    <dbReference type="eggNOG" id="KOG1110">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WELQFRE"/>
    <dbReference type="OrthoDB" id="547796at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005496">
        <property type="term" value="F:steroid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000003">
        <property type="entry name" value="membrane-associated progesterone receptor component 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF72">
        <property type="entry name" value="NEUDESIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0754">Steroid-binding</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="8">
        <location>
            <begin position="6"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="110" mass="12050" checksum="137B7B7516789D75" modified="2009-05-26" version="1">MPPGDLTNEELRRYDGSNPALPILLAAKGRIFDMTRGRDFYGKGGPYNCFAGIDCSRALAKVSLEKKDLNANCADLFASERDVLNDWVAKFEAKYPVVGNVLDSTYDGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUQ0</accession>
    <name>C1MUQ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Voltage-gated ion channel superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_47550</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059535.1">
        <property type="nucleotide sequence ID" value="XM_003059489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUQ0"/>
    <dbReference type="GeneID" id="9684674"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47550"/>
    <dbReference type="eggNOG" id="KOG0498">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CMRELAI"/>
    <dbReference type="OrthoDB" id="426293at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003938">
        <property type="entry name" value="K_chnl_volt-dep_EAG/ELK/ERG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47823">
        <property type="entry name" value="ION_TRANS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47823:SF11">
        <property type="entry name" value="K+-CHANNEL ERG AND RELATED PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01463">
        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="522"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="724"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="781" mass="88227" checksum="640F42996F4A575C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUR8</accession>
    <name>C1MUR8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58910</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059546.1">
        <property type="nucleotide sequence ID" value="XM_003059500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUR8"/>
    <dbReference type="GeneID" id="9684986"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58910"/>
    <dbReference type="OrthoDB" id="10668102at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="519"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="320"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="435"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="566" mass="61997" checksum="51CB37EE1248C9AB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV69</accession>
    <name>C1MV69_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40362</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059615.1">
        <property type="nucleotide sequence ID" value="XM_003059569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV69"/>
    <dbReference type="GeneID" id="9685055"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40362"/>
    <dbReference type="eggNOG" id="ENOG502QST0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CLARREH"/>
    <dbReference type="OrthoDB" id="537706at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045287">
        <property type="entry name" value="PAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35115">
        <property type="entry name" value="CYCLIN DELTA-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35115:SF1">
        <property type="entry name" value="PROTEIN IN CHLOROPLAST ATPASE BIOGENESIS, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="407" mass="42066" checksum="DE677CE84780C27D" modified="2009-05-26" version="1">MMSSAAAAATASLPRVATPTTPRAASSATRRARAAAARAPSPRGGVGVSPAIRRRRATVIASAASSSSSDSSDAAADLASGTTHAEYVASVAGVRAPSELGALVAVLAAQGRAIVAPSERAGLHPRCVPLARDPDTGHTTCLHVTVPFDGARAELEVVSCVGGGDVSMTLLAKTAKEARPPSYVHRAIVEEEKASADAGVAVAAVAAAAGTTGLAMHDPGSFVTLGKELPVYLTLRVGKFPDAMEALAKKHVEKGDEQSALVTCDLYKASFEGWGRPHWYLSRIYADLGRDEEARDAARFAVTDCDWSTIGPETDFADVLERCGWAGKSVAEIKAICETRRGPAASSFDGPKTDAQVAEEEAAALLDQVVAGEKALGEITQRLAECYMNAERGSLAKLVMCASAPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVZ7</accession>
    <name>C1MVZ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_40634</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060125.1">
        <property type="nucleotide sequence ID" value="XM_003060079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVZ7"/>
    <dbReference type="GeneID" id="9685278"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40634"/>
    <dbReference type="eggNOG" id="ENOG502SYJT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TRWHAQA"/>
    <dbReference type="OrthoDB" id="415411at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23315">
        <property type="entry name" value="U BOX DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23315:SF7">
        <property type="entry name" value="U-BOX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="638"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="269"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="476"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="522"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="668"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="677" mass="70467" checksum="18F9D2FD4485070E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWE1</accession>
    <name>C1MWE1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_59732</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type IV zinc-finger family. Class B subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060199.1">
        <property type="nucleotide sequence ID" value="XM_003060153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWE1"/>
    <dbReference type="STRING" id="564608.C1MWE1"/>
    <dbReference type="GeneID" id="9685637"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59732"/>
    <dbReference type="eggNOG" id="KOG1601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="568328at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021660">
        <property type="entry name" value="DUF3253"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172:SF24">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172">
        <property type="entry name" value="OS01G0976800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11625">
        <property type="entry name" value="DUF3253"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="59"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="175" mass="17792" checksum="B2EF967A66F465E4" modified="2009-05-26" version="1">MEARSIHWSPYDRATRREARALADAGTVEITRGGDVVYDGKAKTGEWSGPVRLRLAATTTTTSTAGEGGGGGKAGARDEGGGGGGGGGGEKKRRDGAAAASPTPVAKRRRLGCAQCRAAKTPQWRTGPEGPKTLCNACGIAFLKARKAEAKEEEEDAPPPATADDDAKAGADGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWT8</accession>
    <name>C1MWT8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_6749</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059687.1">
        <property type="nucleotide sequence ID" value="XM_003059641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWT8"/>
    <dbReference type="GeneID" id="9685109"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6749"/>
    <dbReference type="eggNOG" id="ENOG502RZXS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GTPFHTH"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909:SF2">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="214" mass="22681" checksum="82057691EBA373A7" modified="2009-05-26" version="1" fragment="single">PALIIPGFLSGFQKYEEMRRLLESSTLGLGPIAIAPVTIADWVPTLLGGDFRGILDKVDGAADELLSRSKARKIAIVGHSAGGWLARTWLGRAPYSGGKRYRGVDRCDVLLTLGTPHYSLEAYPTLALTNFRYPGAFERGVRYVSVCGAGEIGADFDLLALLRGGAGVDGDGVTPIARALLDGSETLVLDGVAHQPGGEDDAPWYGSPGVVEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWU5</accession>
    <name>C1MWU5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_18223</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059691.1">
        <property type="nucleotide sequence ID" value="XM_003059645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWU5"/>
    <dbReference type="STRING" id="564608.C1MWU5"/>
    <dbReference type="GeneID" id="9685144"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18223"/>
    <dbReference type="eggNOG" id="KOG0769">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KRATNKH"/>
    <dbReference type="OrthoDB" id="2019556at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006862">
        <property type="term" value="P:nucleotide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044712">
        <property type="entry name" value="SLC25A32-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45683">
        <property type="entry name" value="MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="11"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="112"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="243"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH55643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="347" mass="37721" checksum="B2E050835D1FD8C5" modified="2009-05-26" version="1">MASSVPVDDAASATVDAMAGATGALLALLTTYPLMTLNARQHTDRRYVNDNPVTRSNAVTEMRALVREEGGVGALYRGIKPAIVGTVASQSVYNFFYSALRTFYIKKKRQNPGALSSLAIASCAGSINVVMTIPIWTIVTKMQTTRTAKELEERQKERSSGERAWALLRSAEIGFRATARGIYADAGVRGFWQGVVPALVMVSNPALQYAFYESAADRFKAIRARARRRRGASNANASRPIALTAAEVFVAGALAKIAATLLTYPVLLVKSRLQASSKSDDSAMRYDGTIDALRRIVREEGYGAFYRGMGTKMTQTVFASALMFAAKEEIVKATRIAHAKMLRAKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX76</accession>
    <name>C1MX76_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Complex I-ESSS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">NADH-ubiquinone oxidoreductase ESSS subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MICPUCDRAFT_60056</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Complex I is composed of 45 different subunits. Interacts with BCAP31.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB11 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060347.1">
        <property type="nucleotide sequence ID" value="XM_003060301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX76"/>
    <dbReference type="STRING" id="564608.C1MX76"/>
    <dbReference type="GeneID" id="9686082"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60056"/>
    <dbReference type="eggNOG" id="ENOG502S12I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SRKWESW"/>
    <dbReference type="OrthoDB" id="2147978at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019329">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ESSS_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637:SF1">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10183">
        <property type="entry name" value="ESSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00046528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH55116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="110" mass="12110" checksum="9D5FC095E3865F85" modified="2009-05-26" version="1">MSMQSALRTIASRTLRGAQRTQTRKMGAGPPGGFWAEGAQPEGHVNGRLFNETPPPPGQSRKWESWEAPWYLAFGTVTVMLVLGLNNKPNTSSTEWAKVEAQKRLDAAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX82</accession>
    <name>C1MX82_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_60062</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060648.1">
        <property type="nucleotide sequence ID" value="XM_003060602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX82"/>
    <dbReference type="STRING" id="564608.C1MX82"/>
    <dbReference type="GeneID" id="9686085"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60062"/>
    <dbReference type="eggNOG" id="KOG0548">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="83"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="540" mass="58365" checksum="18740C3C22DF8001" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX84</accession>
    <name>C1MX84_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60064</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060649.1">
        <property type="nucleotide sequence ID" value="XM_003060603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX84"/>
    <dbReference type="GeneID" id="9685789"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60064"/>
    <dbReference type="OMA" id="NAMQEFA"/>
    <dbReference type="OrthoDB" id="496947at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="153" mass="16288" checksum="920914805ACA48C2" modified="2009-05-26" version="1">MAAACSHAARVRVAAPRSRGAARATTSSRAFAPRVALARASRVVLARAAEEDVDVDDEKRASEDPEGKISSAMAAFADAGFPSDEDDAMDPISRTKAMNGAVDDLNSLMDSEVEVLGEAFDLLEKLGVKGLAKPPRRGKDADEEEEEKEVEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXI3</accession>
    <name>C1MXI3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_5676</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060401.1">
        <property type="nucleotide sequence ID" value="XM_003060355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXI3"/>
    <dbReference type="STRING" id="564608.C1MXI3"/>
    <dbReference type="GeneID" id="9686135"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5676"/>
    <dbReference type="eggNOG" id="KOG2983">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HDISHAY"/>
    <dbReference type="OrthoDB" id="498146at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="254" mass="27559" checksum="32F399A2F721CEED" modified="2009-05-26" version="1" fragment="single">CRVARWRAVPSLDASAFRATTIPLPSEFVDYLLEDGLSLPAGSEAMPARFGARDDDDDDDDASSSSSASGDDAVAPARSFPTLERVVRDAVDALGGAVAPKLSWSAPKDATWMATTSTTRCLNPGEVFLLLKASDAVAHDLSDAYSPCRDFDADDAAGLRASQLASLRADATLTLTRWRDLSPSGEFRCFVWRGDLDVVCGHFPSRDYVFDVYVTSNRRVKIIDFNPWGGGTLPLLFEWHELQRRGSGEGGFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXK6</accession>
    <name>C1MXK6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_7660</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060413.1">
        <property type="nucleotide sequence ID" value="XM_003060367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXK6"/>
    <dbReference type="GeneID" id="9686146"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7660"/>
    <dbReference type="eggNOG" id="ENOG502S5UD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DIVRMFA"/>
    <dbReference type="OrthoDB" id="498587at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025461">
        <property type="entry name" value="ABA4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34543">
        <property type="entry name" value="PROTEIN ABA DEFICIENT 4, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34543:SF1">
        <property type="entry name" value="PROTEIN ABA DEFICIENT 4, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14108">
        <property type="entry name" value="ABA4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="125" mass="13832" checksum="CB6D1B357D4D1AF4" modified="2009-05-26" version="1" fragment="single">ARWTVRFLRSNVPIVPLCVAYVVMLVASWSPDTLSLMMPGSLEAGISDGFNPQYFPKLDGIMTLLSRRVTAASAWLHLMCINFFVGKHATIRALREGIPVWHTLALTLLTGPLGLCSHWVTRAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXR0</accession>
    <name>C1MXR0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_7897</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060734.1">
        <property type="nucleotide sequence ID" value="XM_003060688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXR0"/>
    <dbReference type="STRING" id="564608.C1MXR0"/>
    <dbReference type="GeneID" id="9685880"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7897"/>
    <dbReference type="eggNOG" id="KOG3299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498744at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF20">
        <property type="entry name" value="IMPACT FAMILY MEMBER YIGZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Impact N-terminal" evidence="2">
        <location>
            <begin position="21"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="152" mass="15433" checksum="F7DD5846FFEDEDDB" modified="2009-05-26" version="1" fragment="single">AAGDGATLRLLERVVAETEVKKSKFVAIAAPVDSPSRAMAFVESNGDPKASHNCFAYKIGQSTRSSDDGEPGGTAGLPMLSAIEGSGFDNVAVLVTRYYGGTQLGAGGLVRAYGGAAAKALEGAPSKVTYPVVDALIDSPAFDDLGGIYSSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYI8</accession>
    <name>C1MYI8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_47829</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060574.1">
        <property type="nucleotide sequence ID" value="XM_003060528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYI8"/>
    <dbReference type="STRING" id="564608.C1MYI8"/>
    <dbReference type="GeneID" id="9686012"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47829"/>
    <dbReference type="eggNOG" id="ENOG502QUQI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="INRGDNC"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="entry name" value="Survival protein SurE-like phosphatase/nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00060">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="5'-NUCLEOTIDASE SURE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457:SF0">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G01070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SurE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival protein SurE-like phosphatase/nucleotidase" evidence="4">
        <location>
            <begin position="15"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="353" mass="35845" checksum="74575C16D7DAADEB" modified="2009-05-26" version="1">MALGSAAPRRDRASVLVVNDDGIDAPGILALVRALANCGTFDVYVAAPDAERSACSHCISIHAPLAVEPRSIPGAIAAYAVSGTPADCAMLATGALFPSIRFDFVVSGVNRGDNLGRHVIYSGTVAGAREGAMKTGGVGVAVSLCSYSRDADYSDAASVAAETLTAVRSTLGVYGALAGKVLNVNVPHRGDGNSGGGSGIKGVKLTRPGFSCTQPDWVRVSSPGEDAEVAAAAPAPPKSDDAYGAGVVPSVVVANDETHENGALVSDTGGDAAWTKGVRWFRNRPGPHTRDDGDGTDQRAIDDGYVSVSILSCEFESSDGGFEGGRESAWATGSDAGEVLRGYRDARCIGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYK9</accession>
    <name>C1MYK9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68910</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060293.1">
        <property type="nucleotide sequence ID" value="XM_003060247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYK9"/>
    <dbReference type="GeneID" id="9686023"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68910"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="120" mass="14143" checksum="22106CD86DD31EFF" modified="2009-05-26" version="1">MNSTPTSLCMERPSARRRRVRENLRRRRRVQPRGVARARGRRVVARVSARRGRAGDEPVGMQRGFVGVHSARPARRRRRRRRASDSREDEEDRGRSRYRNGRSQSITYGEVAHRDLTRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYY5</accession>
    <name>C1MYY5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_60534</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060865.1">
        <property type="nucleotide sequence ID" value="XM_003060819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYY5"/>
    <dbReference type="STRING" id="564608.C1MYY5"/>
    <dbReference type="GeneID" id="9686559"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60534"/>
    <dbReference type="OMA" id="CISERYA"/>
    <dbReference type="OrthoDB" id="285793at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140993">
        <property type="term" value="F:histone modifying activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003889">
        <property type="entry name" value="FYrich_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003888">
        <property type="entry name" value="FYrich_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05965">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05964">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51543">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51542">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="210"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="480" mass="49952" checksum="959539BA614AE152" modified="2009-05-26" version="1">MDARTPTPPPRRAAASLSRRDTPPARVVARDDGVAPAPAAFFLSASRASSSSPPRFFAPAAAPAIPPPSTPIALAPAPAVDAADRATPPTPTPTPTHSYFSSLFAALAPADASRNRLVELKKRAKASRATATIASALETGGAFAETFPPPPAPPRATKRATTTTTTTTTTPDATPLAFLFPEGALYAVSSGRRPKNGVSTGRKKRPRREEEEERVEDSFCNDDDATDAREEEEEEEEQEDGGDDDGDDNSEAGAAAAAAAAAAETTPKNSSGRKPPPPLALPRGEFKLSKWAVDASAVPSPASPPVTAPFTVAGGVTVLAIGTIAPSLSGRVSGHSAYVLPIGFVSRRRYNSTTRPDVKTTYESRVLVVAAAADEKDGESAAAVASRTRVPCPTRVPCPPPSKCVVRVADVNDPSVFFVGSSPTQAWAQVIRAVNEKSQTRKRTAVSGPQFLGLTAPVVANEIAKLPGYAACVEHMRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ37</accession>
    <name>C1MZ37_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_19653</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061147.1">
        <property type="nucleotide sequence ID" value="XM_003061101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ37"/>
    <dbReference type="STRING" id="564608.C1MZ37"/>
    <dbReference type="GeneID" id="9686329"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19653"/>
    <dbReference type="eggNOG" id="KOG2106">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498908at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885:SF3">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="227" mass="25170" checksum="4D9365F28A27915B" modified="2009-05-26" version="1" fragment="single">MPRTAVSVYHSFGFESTKRNNLHYIAPDVVVFTVGNEVQTLHLVTGAQTYLHGVDGKGVGMVCVHPSKRILAVGEKGTDPNVYVYEYPRMKLRKIMRGGTERSYACGRFSPDGDTLATVGGFPDFWLTLWDWRTESIVLRSKAFSQDVFDVQFSPFFPGQLTTSGTGHVRFWKMAETFTGLKLQGEIGRFGNEDLSDIAGYAELPDGKVLSGTESGRMLLWDGGLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ77</accession>
    <name>C1MZ77_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_19598</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061166.1">
        <property type="nucleotide sequence ID" value="XM_003061120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ77"/>
    <dbReference type="STRING" id="564608.C1MZ77"/>
    <dbReference type="GeneID" id="9686350"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19598"/>
    <dbReference type="eggNOG" id="KOG1497">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KNIMHTV"/>
    <dbReference type="OrthoDB" id="295656at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="195"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="405" mass="44314" checksum="9B93207754940384" modified="2009-05-26" version="1">MEARLAAIAAEGGDQKEKTQKYQTVLTESLSNGGDVEGLKQMVVHMLSDVVPLVTSRQILSTLCSEAKSLPAAQHKDVAEFALEKITPRVVSFEEQVSVLREGLAKLLKDDGKASEAASMLAGIDLDSGIRNLSDEYKLRMCVDIAMLYLEDDDATNADAFIKKASFLLGACKEGEALELQYKSCYARILDAKMKFTEASLRYYELSQTELGRDLGDGKVVTESDLAASLTSAIIACILAAAGPQRARVLATLYKDDRCAKLPIYPVFEKVYLERILRADEAASFASTLRSHHLTVGEDGLTVVTRAISEHNLLSASKLYNNIKIDELGTLLGLPPDRAERTAARMIGEERMAGSIDQVHGFIDFQDPSDGDVINEKWDAQITSVCTQVNDIVDMMENKGIPIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZR1</accession>
    <name>C1MZR1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Expansin-like EG45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60822</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060996.1">
        <property type="nucleotide sequence ID" value="XM_003060950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZR1"/>
    <dbReference type="STRING" id="564608.C1MZR1"/>
    <dbReference type="GeneID" id="9686704"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60822"/>
    <dbReference type="eggNOG" id="ENOG502QR06">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498139at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009664">
        <property type="term" value="P:plant-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22271">
        <property type="entry name" value="DPBB_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002963">
        <property type="entry name" value="Expansin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007112">
        <property type="entry name" value="Expansin/allergen_DPBB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31867">
        <property type="entry name" value="EXPANSIN-A15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00837">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50842">
        <property type="entry name" value="EXPANSIN_EG45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912193" description="Expansin-like EG45 domain-containing protein" evidence="1">
        <location>
            <begin position="34"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Expansin-like EG45" evidence="2">
        <location>
            <begin position="173"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="303" mass="32524" checksum="5325F67FC72D609D" modified="2009-05-26" version="1">MTTTPTFSSRRAAAFAAAACLALLAASARVVAADGTATTTAPPPADASSSTPPSFFSRVARFLPRVARAPDARDAADAEEAAEIARLANRADQIPQRPPHNVTVEYRSRRELGELDGWLDARATWCAAQTDSSTTRRSRRVAAAVAHDIPPSIHPYRYGGPGGAGPDGMSIYTGSCGFGQVTNHFVTAWHTDGGYDWGLTEKCGQCYEVMCVDGRTRGHDWSDLGPWAGCQEAGKKSVTVMISDSCPCHHPNQGNKRWCCGDATHLDLSYAAFDQIAERHRGVVDLKVRPGDCSKQGSVMHYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZV1</accession>
    <name>C1MZV1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_48134</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061017.1">
        <property type="nucleotide sequence ID" value="XM_003060971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZV1"/>
    <dbReference type="GeneID" id="9686723"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48134"/>
    <dbReference type="OrthoDB" id="538354at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="472" mass="48800" checksum="C1B13531AD65ADF4" modified="2009-05-26" version="1">MVQIEDDTARLDTVCSPLQYHANASVTQVVGTSNFPPSFAAVGYAPCFKGFGPAPGSSSTAPFATDAASSPAFVKRAEVSPSPSGGAFQHVKLFKNVLVAADGAASAKIYVFDVRDWKEKQVIRVGAVPKEHGGVGEGADGDDAALAPAAVTMLAFDGLVIAAGTAEGFVHTWKLMEHEGKRGYARLLNPLKVDSQPITRVHLGTQAELLTAYAASKRTLVCWELSTGKLRGAYNVDGVAKGVPMALTANCESVIACVHAHKTSDGGGKGNKTPPLAALLDVQSGEGGAVKDVSPLLGEGDPACIAFDGELLAVGTTAGAVIAWNVGEGYAAWKGYHGGSVDAICSVPDNHRPRLLSGAADRTLLLWDKTGMVQARLEVGAGVTSLHAPTSRTAVCGTSAGMVELLALCAPDATADEALTVAAKGGRRVGNELVATAWRHDPGDAPDSRRSFEVRSIHWSLYDPVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1N101</accession>
    <name>C1N101_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_1615</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061722.1">
        <property type="nucleotide sequence ID" value="XM_003061676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N101"/>
    <dbReference type="STRING" id="564608.C1N101"/>
    <dbReference type="GeneID" id="9686926"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_1615"/>
    <dbReference type="eggNOG" id="KOG0348">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IHEQICE"/>
    <dbReference type="OrthoDB" id="422663at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="13"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="236"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="542" mass="57706" checksum="D53512A2BEA673D3" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1N146</accession>
    <name>C1N146_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_20256</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061747.1">
        <property type="nucleotide sequence ID" value="XM_003061701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N146"/>
    <dbReference type="STRING" id="564608.C1N146"/>
    <dbReference type="GeneID" id="9687186"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20256"/>
    <dbReference type="eggNOG" id="KOG4283">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="XELYSGS"/>
    <dbReference type="OrthoDB" id="497510at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031464">
        <property type="term" value="C:Cul4A-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000109">
        <property type="term" value="C:nucleotide-excision repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042238">
        <property type="entry name" value="Rad28/ERCC8/Ckn1/ATCSA-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202:SF1">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="214"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="260" mass="27240" checksum="B36FC20EF21CD861" modified="2009-05-26" version="1" fragment="single">MSPSPGDAWYPTSASLANRELGLARPRAFLADVASRRRDALSLAGDKTLSMPWASGVNALRVDETEHRYLLAGATDATIAVYDTAQPSRVDPRTGVATHDPILRVRRGAGDGAARSPGHAFAVSSVDWYPVDTGMFFTASFDQTVAGWDANACARVVDFAFEDKVYCIATAKGGRGGGIGGGGGGATHALVACGLAHPVVKLCDPVSGNVTHALSGHRDAVWALEWARGSEYVLVSGGGEGDVRLWDVRRAGAFMVLDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1L6</accession>
    <name>C1N1L6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleosome/chromatin assembly complex protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51454</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061578.1">
        <property type="nucleotide sequence ID" value="XM_003061532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1L6"/>
    <dbReference type="STRING" id="564608.C1N1L6"/>
    <dbReference type="GeneID" id="9687284"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51454"/>
    <dbReference type="eggNOG" id="KOG4364">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QCSSHVV"/>
    <dbReference type="OrthoDB" id="79480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033186">
        <property type="term" value="C:CAF-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272:SF0">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="685"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="777"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="695"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="841"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="886"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1252" mass="130678" checksum="3DD0AB57445B1354" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1Q3</accession>
    <name>C1N1Q3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_35564</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062158.1">
        <property type="nucleotide sequence ID" value="XM_003062112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1Q3"/>
    <dbReference type="STRING" id="564608.C1N1Q3"/>
    <dbReference type="GeneID" id="9687597"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35564"/>
    <dbReference type="eggNOG" id="ENOG502QQIK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045735">
        <property type="entry name" value="Spore_III_AA_AAA+_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20953:SF13">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20953">
        <property type="entry name" value="KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19568">
        <property type="entry name" value="Spore_III_AA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="201"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="534"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="560"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="570" mass="60265" checksum="6CA514964120BE2D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N285</accession>
    <name>C1N285_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48472</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062247.1">
        <property type="nucleotide sequence ID" value="XM_003062201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N285"/>
    <dbReference type="STRING" id="564608.C1N285"/>
    <dbReference type="GeneID" id="9687487"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48472"/>
    <dbReference type="eggNOG" id="ENOG502RGTB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="691424at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006502">
        <property type="entry name" value="PDDEXK-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31579">
        <property type="entry name" value="OS03G0796600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31579:SF1">
        <property type="entry name" value="OS03G0796600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04720">
        <property type="entry name" value="PDDEXK_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="488" mass="51856" checksum="39273549D4E348DF" modified="2009-05-26" version="1">MTTTLLPQPGTATFPGLRKTSPEQFPPRLWPARTTATNASFALAPRDAPASPASGRNKIDEAMDVDVDDATFDFDLLFDTGSGSRAPTPPPTPPTLARQLPRLTLAESAEDARVRCAREPSEIVFRPRPFGFEKTHIILNPSLRRLLIILALPSSSSVRRLARELTRPKNDLARAIRDRFDAACLEVGPGEMGDDAHVERLRVAFEAISAAADDDDDFHSRRPTTASSHVAEGYVSDGSECSGRGGGSVSGSTSRANVAVAPGSTGRAALLNLRHAFLWIDVGGGGAAATTAAAARADPSSSDASPAPPAPPARDDETTLILEPDIRAHFVVSRPTEAYSRLLRSLPERFVGTRLDLAKLVDVVCDEMRASFDANGMSQPPWRRPSSIMSKWLVPAQSCVGGARDDAAGAGGTKSARARSDPATKPLLFATTTPIFERGDDDAERRRRWSVDGNPERVGPAGEKPRGRGGSPTFVGFEAIGERVGAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2E5</accession>
    <name>C1N2E5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_51499</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061860.1">
        <property type="nucleotide sequence ID" value="XM_003061814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2E5"/>
    <dbReference type="GeneID" id="9687512"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51499"/>
    <dbReference type="OMA" id="TSANAWE"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052606">
        <property type="entry name" value="DnaJ_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653:SF2">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23082">
        <property type="entry name" value="Myb_DNA-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912245" description="J domain-containing protein" evidence="7">
        <location>
            <begin position="25"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="41"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="9">
        <location>
            <begin position="430"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="191"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH53572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="55009" checksum="271C83676E5B5DA9" modified="2009-05-26" version="1">MRLLPQVLFLAILLAILLPRGASSAPPLPPCRPGAPPGAPSCYALLHLERSLDASARRVRKAYRAAALLVHPDKCANCDDATRLANQRRFVDLAFAYETLRDDASRFDYERGAGRWAPGKADANPTRDDTFDPSSTRGGAWARSRFDEARDPLLTTRGWAALAACALVVAAVRAVARACDRAARRFARDRAATTGARKGAARRRRERVESEARAREVATTTGTQRREHRRREMNEAAAAMASRVAAAARDLNAATGGGVDDDDDDAVPERLRTLARQGSLAAHQTMKLLARTRELWGSGSVGHGVSDTSVRHDVSDAANTDGMAATLTRTFLALASSPPPWDSLVVGDEALRTRLAAWGKEAARLGRDFVPSPFALGCTGWDDGTGDGVDDMRRLTRSLRAWERSSNQFATLVRELAAHARSCAATLRAADARDRARWSKVERATLKRAMTTHPKGTERRWDRIAEAFEGRRSVEEVKRYVAEMVVLARDRAGASAEGESSGAPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2G3</accession>
    <name>C1N2G3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_35474</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062083.1">
        <property type="nucleotide sequence ID" value="XM_003062037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2G3"/>
    <dbReference type="STRING" id="564608.C1N2G3"/>
    <dbReference type="GeneID" id="9687308"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35474"/>
    <dbReference type="eggNOG" id="KOG3387">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IKNQIYA"/>
    <dbReference type="OrthoDB" id="1924699at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21104">
        <property type="entry name" value="SNU13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000002">
        <property type="entry name" value="NHP2-like protein 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="10">
        <location>
            <begin position="22"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="126" mass="13656" checksum="2CBE4231CE83C3C1" modified="2009-05-26" version="1">MAEVNPKAYPLADAQLTITILDIVQQAANYKQLKKGANEATKTLNRGISEFVVLAADTEPLEILLHLPLLAEDKNVPYVFVPSKQALGRACGVSRPVISCSVTTNEGSQLKSQINNLKDAIEKLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2L3</accession>
    <name>C1N2L3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41840</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062106.1">
        <property type="nucleotide sequence ID" value="XM_003062060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2L3"/>
    <dbReference type="GeneID" id="9687335"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41840"/>
    <dbReference type="OrthoDB" id="10619454at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="111" mass="11784" checksum="85AC479DDF2A1A47" modified="2009-05-26" version="1">MIRRAISDAPSYGDRGTFEDYEGWSFWTFFAAVHWILLVTTLPLFIEAAAGCQGERKKRIDGARGYTDYGGGGGGGEYAALPAAPPTKRLTFDTGGTEIVEEDSAATAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2N0</accession>
    <name>C1N2N0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_69885</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062114.1">
        <property type="nucleotide sequence ID" value="XM_003062068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2N0"/>
    <dbReference type="STRING" id="564608.C1N2N0"/>
    <dbReference type="GeneID" id="9687344"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69885"/>
    <dbReference type="OMA" id="DADWSTH"/>
    <dbReference type="OrthoDB" id="10071381at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21747">
        <property type="entry name" value="Rad21_Rec8_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="entry name" value="Structural maintenance of chromosome 1. Chain E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039781">
        <property type="entry name" value="Rad21/Rec8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006909">
        <property type="entry name" value="Rad21/Rec8_C_eu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585:SF69">
        <property type="entry name" value="FI11703P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585">
        <property type="entry name" value="SCC1 / RAD21 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04824">
        <property type="entry name" value="Rad21_Rec8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein C-terminal eukaryotic" evidence="2">
        <location>
            <begin position="451"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="503" mass="53675" checksum="79FC2532AF431D45" modified="2009-05-26" version="1">MYDDFEHQYAHDDRIHDDGVGSDLEDVYDDAFYPSSAYKTPNGAKRDGDAAITDPDARADVQLEDYDDAGDGAEFGGGGDDDGAVGMEQVAGGMDGIEPLPLDDDLEDENGVRGTVVTAAGAAGVTFKTPSAAGAPPPNENDPPNTNASSGIVVDWGKTAQKGRRPTDVDGLPGAAVKPAPQARPRTKPREKLIIDDVTVLSNEHIRNQLKDTSDIVRKRTPGALRLLVDPRDTDVPFDHPDDVDVDGLPTVGYFKEGWTCVVPEEASVAHDMIRGDYMDWDPVMNHRMSPEMAKIRRACVAHLWKRAGEKWGGGYAAGDAAAAAAKGSTERGGGGFGFDDDGGDFGGGGGGFDDDDDFAMPPRDDDDFNVDERGTSRLRADAENAADVVDRLGPLGSEPPTPANAPKGDIDWSVHTKRMLSDLAPRLNTPRAKPVKVSEMLKDVGTETKPCTKSEAARVFYQVLVLKTHGFVELAQREDYGDIDIAAGPKMKDVAKGKTAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2V3</accession>
    <name>C1N2V3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48398</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061943.1">
        <property type="nucleotide sequence ID" value="XM_003061897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2V3"/>
    <dbReference type="GeneID" id="9687587"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48398"/>
    <dbReference type="OMA" id="WFILGEL"/>
    <dbReference type="OrthoDB" id="495053at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="190" mass="20921" checksum="BD050E72C2DC8BF0" modified="2009-05-26" version="1">MQRPSMRRNESLQDLSAVAKHFPVYLERRVATESFRHEAFQYALWLPLAGVAKYFGCHRTAYTFLTWFILGELLLIYMHQKVVKFVRWWMVLTFVAGAAALFHGQLNLSENAYWQFLVWYVIAGIVGFAVVLPFVPRRFLQGAPGVLFELGLIRRGFAGSTGSTGGAAGAGAGDGDGDGAGGGGGDKKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N314</accession>
    <name>C1N314_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-methionine-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_8028</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062300.1">
        <property type="nucleotide sequence ID" value="XM_003062254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N314"/>
    <dbReference type="STRING" id="564608.C1N314"/>
    <dbReference type="GeneID" id="9687970"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8028"/>
    <dbReference type="eggNOG" id="KOG1635">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FWCLEHD"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050162">
        <property type="entry name" value="MsrA_MetSO_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42799">
        <property type="entry name" value="MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42799:SF2">
        <property type="entry name" value="MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="8">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="19782" checksum="317214E6EB709FF0" modified="2009-05-26" version="1" fragment="single">ATFGGGCYWGVEKWYAKDFNETHPGAVVATNVGFMAPKDAKAKPNPSYREVCGGRTGHVEVCQVKFDATKCSYEDLNAHLYTFHDPTTTNRQGNDAGSQYASVIFVHDEGQRKDAERVNARTQRALDRGKIKTFQRDKIVTRVEDATEYYPAESGHQRYLEKHPNGYCNHRRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N345</accession>
    <name>C1N345_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_52032</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062546.1">
        <property type="nucleotide sequence ID" value="XM_003062500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N345"/>
    <dbReference type="STRING" id="564608.C1N345"/>
    <dbReference type="GeneID" id="9687755"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52032"/>
    <dbReference type="eggNOG" id="KOG1651">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CTRFTAK"/>
    <dbReference type="OrthoDB" id="446890at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="230" mass="23949" checksum="8D4287A6DAC4464E" modified="2009-05-26" version="1">MAMAASSARARATVSCRASAARGARGVASTSSAFAGTTPRARRALAATAFAGATLASATTTTTTTTTRAFFGGGGGKVSGSAHDFTVKTIDGVDVSMGSFKGRACLVVNLVTLYDKYKSTGKFEVLAFPCNQFGAQEPGSDAEIKAFAAGYGATFPMFSKIEVNGDNAHPLYKWMKDAKKEAGPAGMLGNDIKWNFGKFLLDGDGNVVERYVPTTSPLQIEDDVKKLVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N372</accession>
    <name>C1N372_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_52061</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062557.1">
        <property type="nucleotide sequence ID" value="XM_003062511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N372"/>
    <dbReference type="STRING" id="564608.C1N372"/>
    <dbReference type="GeneID" id="9687771"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52061"/>
    <dbReference type="eggNOG" id="KOG2997">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VKCMNFR"/>
    <dbReference type="OrthoDB" id="2117972at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22151">
        <property type="entry name" value="F-box_AtGID2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045464">
        <property type="entry name" value="Hrt3/FBXO9_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874:SF9">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19270">
        <property type="entry name" value="FBO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="138"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="442" mass="49844" checksum="31A34DF5131F8551" modified="2009-05-26" version="1">MALKRECTGGKPARARRRHVSCRRDSASRRVSPPRRAATRADARARRPPPRASAESRPRPSEVAMVVLGGMRLRLLDSDDDDDDDVAAPSTPENPRKPSDALPAEAFLATKRAWLDMYNNRVTVPANCRDPKTSRRLALIQRLLPDELVVEIFARADPRSVSRAACACRPWRVLARSEIVWRAACHRAWAPRESRDVTARIARERHRGSFRRMFFDRARVRTEGLYVSRNTYVKPGFTDLEHGVKGAPVHLVTYYRYIRFFGNGEFIAKTSPTKVGVAHKQMREKKTALGDDTVVHGFYSLPCDGDESRLHLASAPRIRADSTFTTTHYWLRLRGTHPGASNRLDFVKLASGAFLLITPVPVRPLDDDEDAPAPTEEAWREVDDPSLAYRRSCGYDARAYDGTAAVRELSRGLNTLVFVPWEDAVDHVLNLGTREMDFYVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4K0</accession>
    <name>C1N4K0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_36077</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPO2/CSE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063013.1">
        <property type="nucleotide sequence ID" value="XM_003062967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4K0"/>
    <dbReference type="STRING" id="564608.C1N4K0"/>
    <dbReference type="GeneID" id="9688243"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36077"/>
    <dbReference type="eggNOG" id="KOG1992">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AENEFLM"/>
    <dbReference type="OrthoDB" id="3268246at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000507">
        <property type="entry name" value="Exportin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005043">
        <property type="entry name" value="XPO2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF8">
        <property type="entry name" value="EXPORTIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03378">
        <property type="entry name" value="CAS_CSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="29"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="996" mass="106883" checksum="644291F03A52128E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4P3</accession>
    <name>C1N4P3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_66821</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063034.1">
        <property type="nucleotide sequence ID" value="XM_003062988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4P3"/>
    <dbReference type="GeneID" id="9688474"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66821"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="96" mass="9890" checksum="87BE09E72E762CA5" modified="2009-05-26" version="1">MLNSDMYRSLIDPSGSAEMMKTAQLCADQFVCFVKVRGGGGGAGGAAGGGGGGDGGEIFLWLVGKRRGGPTVDTRGCWMTEAVSRVRPEDVDAYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4R0</accession>
    <name>C1N4R0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42467</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063041.1">
        <property type="nucleotide sequence ID" value="XM_003062995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4R0"/>
    <dbReference type="GeneID" id="9688275"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42467"/>
    <dbReference type="OMA" id="PDRGFWS"/>
    <dbReference type="OrthoDB" id="10369099at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="610"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="822" mass="84066" checksum="8D8F40BAD2A3A7F8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N517</accession>
    <name>C1N517_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52764</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062892.1">
        <property type="nucleotide sequence ID" value="XM_003062846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N517"/>
    <dbReference type="GeneID" id="9688332"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52764"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="226" mass="24111" checksum="87CCBAB23C8CC502" modified="2009-05-26" version="1">MAYVAVSAAPTVSPSAIASSLNSMNGFRGGGGASAASLARRSSSALAFAASILCLRVLRCACSSSRKNCDSDCRATTRGSASVFRERSSPPIARVQRAHDAGGEEEEKVDDDDDASREDARRSIAREVLSSARRSSGRTCSDFIASLKGLKGPRYEPGLNSPFHRVSRYIAKGPRYEPGLNSPFHRVAALLVLYIAKGPRYEYSSPFHRVAALSLNTRKVLGTNPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N526</accession>
    <name>C1N526_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48724</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062898.1">
        <property type="nucleotide sequence ID" value="XM_003062852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N526"/>
    <dbReference type="GeneID" id="9688338"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48724"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="219"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="594"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="961"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1084"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="367"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="466"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="741"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="601"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="620"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="961"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1084"/>
            <end position="1095"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1149" mass="120952" checksum="DFF43D4F388AF9FD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5I6</accession>
    <name>C1N5I6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42636</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063369.1">
        <property type="nucleotide sequence ID" value="XM_003063323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5I6"/>
    <dbReference type="GeneID" id="9688605"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42636"/>
    <dbReference type="OMA" id="CAWWPEL"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="208" mass="21836" checksum="BA89A7294518B83F" modified="2009-05-26" version="1">MIVAHVDGSVEPKRFPPVAGVGVYYRPGDALNYAARAPLAEDNNATELLAVFVALVRHPRRSPITIRTDSRATLDVLERLARGDGLRAFKFKGARGAASCRATLFWLRAVLFWREAATAVRKVKAHAAATPDNATADALARVGANASAKRVVPYAPTGGGFFRLGGGGGGGGGGGARRYEVALFFEIARFLSGARGEGNGALEDIVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5N4</accession>
    <name>C1N5N4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_63720</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063394.1">
        <property type="nucleotide sequence ID" value="XM_003063348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5N4"/>
    <dbReference type="GeneID" id="9688833"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63720"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1002"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1002"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1028"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1054"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1054" mass="108665" checksum="C76BEE22203EF604" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N645</accession>
    <name>C1N645_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53152</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063471.1">
        <property type="nucleotide sequence ID" value="XM_003063425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N645"/>
    <dbReference type="GeneID" id="9688910"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53152"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="89" mass="9702" checksum="FAB08EF9FCBB85D0" modified="2009-05-26" version="1">MVAANLPYLIAAPVGVGAIVLQRTFRRKKGKGDDEKGRRDGDGDVTAFACERVCTSDRLIKRLGYLAKARSRSARARRDGATPRASRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N774</accession>
    <name>C1N774_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_36635</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063686.1">
        <property type="nucleotide sequence ID" value="XM_003063640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N774"/>
    <dbReference type="GeneID" id="9689291"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36635"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ENEADCC"/>
    <dbReference type="OrthoDB" id="441812at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF113">
        <property type="entry name" value="[FRUCTOSE-BISPHOSPHATE ALDOLASE]-LYSINE N-METHYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rubisco LSMT substrate-binding" evidence="5">
        <location>
            <begin position="372"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="538" mass="57512" checksum="94C5FD4FE5104470" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7R9</accession>
    <name>C1N7R9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_53804</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063956.1">
        <property type="nucleotide sequence ID" value="XM_003063910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7R9"/>
    <dbReference type="STRING" id="564608.C1N7R9"/>
    <dbReference type="GeneID" id="9689582"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53804"/>
    <dbReference type="eggNOG" id="ENOG502S1IC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PWHWARN"/>
    <dbReference type="OrthoDB" id="71307at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="85"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="161"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="202" mass="22647" checksum="47C424BFA7B0BFD4" modified="2009-05-26" version="1">MVERNPWYSRVKGPFPESYGCVGVKPDGGGSMRGRGTVGKMRVHHAVFNRDSGAFYTLVPIRPRTRDLIKKLIDDGDDVNEVEGAGNTPLFCAAYDGWNEGVELLCELGAKVNASNNAGDTAWQWAANMMHDSTCEVLEKLGADKEYLGRVIVKDFYDLPDGKEHPKPSLEYLEWQKQKDAEREVDETAQWDEWSKPGKPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7S4</accession>
    <name>C1N7S4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyruvate dehydrogenase E1 component subunit beta</fullName>
            <ecNumber evidence="5">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_30110</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="5"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063959.1">
        <property type="nucleotide sequence ID" value="XM_003063913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7S4"/>
    <dbReference type="STRING" id="564608.C1N7S4"/>
    <dbReference type="GeneID" id="9689400"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30110"/>
    <dbReference type="eggNOG" id="KOG0524">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VRLCTKD"/>
    <dbReference type="OrthoDB" id="10266385at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027110">
        <property type="entry name" value="PDHB_mito-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624">
        <property type="entry name" value="DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624:SF96">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Transketolase C-terminal" evidence="7">
        <location>
            <begin position="190"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="314" mass="33410" checksum="2D5DD69E099AD5E1" modified="2009-05-26" version="1">MVRDPTCVAHAEDLQAGSSYNIPANTQQAFGTLRAADEIIDEGHFIGKARSALGEAMNGYRPIVELMNANFGIYGMAELSSAGNTFATTGGQFNMPMTVIGAGGTAPNQSLGAEHSQPFHAYIMGIPGLKICTASKAPYGLAKSMIRDNGPGVLLLPVKLMKTRGPCEVDNFLPLHKATLQHEASAASIAAGKAVTVLTYLHGTKESEDAIETLTAEGYDVDLIELTCLKPFDKETIQASLARTHKLAILDESTRSGGVGATFSALVSEELFDELDAPVRRLCMEDAPVPYATEMERVMVKRAADLVEGVKSMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8B8</accession>
    <name>C1N8B8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_23328</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064241.1">
        <property type="nucleotide sequence ID" value="XM_003064195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8B8"/>
    <dbReference type="STRING" id="564608.C1N8B8"/>
    <dbReference type="GeneID" id="9689496"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23328"/>
    <dbReference type="eggNOG" id="KOG0713">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="INTEIFM"/>
    <dbReference type="OrthoDB" id="552876at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051434">
        <property type="entry name" value="DnaJ_C_subfamily_member5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027:SF7">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="16"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="82" mass="8980" checksum="FC3CE62F3B22CEFB" modified="2009-05-26" version="1" fragment="single">MAPPSPAPEDERDSVDLYATLGLTRDASSGAIKKAYRTLALRFHPDKNPGDEVATETFKDIGKAYAILSDAKKKKYYDDTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8K4</accession>
    <name>C1N8K4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Secretory carrier-associated membrane protein</fullName>
            <shortName evidence="6">Secretory carrier membrane protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_54121</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Probably involved in membrane trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cytoplasmic vesicle</location>
            <location evidence="6">Secretory vesicle membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the SCAMP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064282.1">
        <property type="nucleotide sequence ID" value="XM_003064236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8K4"/>
    <dbReference type="GeneID" id="9689541"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54121"/>
    <dbReference type="eggNOG" id="KOG3088">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IFFAQVC"/>
    <dbReference type="OrthoDB" id="242866at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055038">
        <property type="term" value="C:recycling endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030658">
        <property type="term" value="C:transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007273">
        <property type="entry name" value="SCAMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10687:SF2">
        <property type="entry name" value="SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10687">
        <property type="entry name" value="SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04144">
        <property type="entry name" value="SCAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="8">
        <location>
            <begin position="299"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH51904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="356" mass="38128" checksum="23BD22004F9D368D" modified="2009-05-26" version="1">MSDNPFEEGNAEPNPFQASAEVEPANPFNPSPTDVAPTYDNPAYDDAAPAPVTTFGAYDVGAYGSDAAPAPSASSPPSAAAAADAYQPSGGAYGGAGTALASAAAAYGSGSKSPGSDGGETSVRVRELEQREAALRRRREEVIRREQALANAGQKNWPFKRYAIAFHDIELEIPEECQRAVHHAHYAFWGLVFCLTYNFLFAASAAFFGLGDFAAWIMAILYLITGVPGAYFFWYARLYNATKNDSALGYAWFFIVFLVHIAFCLFAFIAPPDAFGTAKYSLAGVMSTAEMEKENSSIGGVYAFGAALWFLELLWSVWVIRGVYLAFRGQGHTVTEARNAVAKDAAFGAAKSGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8S0</accession>
    <name>C1N8S0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_54218</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064496.1">
        <property type="nucleotide sequence ID" value="XM_003064450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8S0"/>
    <dbReference type="GeneID" id="9689764"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54218"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="191" mass="20742" checksum="2EE28FB5A3268553" modified="2009-05-26" version="1">MATATADDRYVDASSRAMRRSNSLEAVAAWDDSQATRGHEIREHTDPAFTRFFESHPTPARRADGERDRDVGPASSPKVSTLAVKLKESQAELAKTTSELDAAKARNKLMEEHIETITHREDIVNANVTLVALFVALALALALALTLAAALFFEPVGLPIARTMARRWGDACGCDDKCKASTLGGFMGWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8V0</accession>
    <name>C1N8V0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_66489</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064513.1">
        <property type="nucleotide sequence ID" value="XM_003064467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8V0"/>
    <dbReference type="GeneID" id="9689954"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66489"/>
    <dbReference type="eggNOG" id="KOG1819">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="119"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="187"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="230"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="334"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="438" mass="47563" checksum="7B02D2305E2E2872" modified="2009-05-26" version="1">MTDATTDATAAPRDAAPKGDDDVVNKKTVDQTTRSASSSPAAPTTPPREPSSPPPRAGLDAFKTAVERRGRELRAAVAASVASTAVMGRGRRRQISRPRLDTSHWVPDASVRACASLACATPFTLTRRRHHCRGCGGVFCARCVDARLLFDPRTSRPTPRGDVGAVEGRVCRACYERAFDERVGARGAGGWEDATGVDEEESDDDDDDEFHDATPVAADDDDDDDDDDVLKERRSPRERGRMETSHDDVERREDERNQNRDDDDDDDDDDDGDAREHGIDSVYKSPPVKVPSSSAKTPGSVDATPPASSFEAARARIEAFSKNPDGGPGPGPGPADAAAKAKARASSDADAEQVARETSELLCDTPRAMKRASPGTMRALISRYARLLREQARLTEDAREVAKTVRARPQNDFFFHVIKSVAYMSPNPSYMSSHRITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9I1</accession>
    <name>C1N9I1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54512</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064623.1">
        <property type="nucleotide sequence ID" value="XM_003064577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9I1"/>
    <dbReference type="GeneID" id="9690064"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54512"/>
    <dbReference type="OrthoDB" id="423807at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="207" mass="20996" checksum="DC5ABDF41717B2ED" modified="2009-05-26" version="1">MARRARAAAPAERDASRPGVRSRGAGAAVRGGAAARARRRVRRREATSATTAPAAAASAIERNAVTDDAADITAAASFAYASSPSTPLTALGSNVVPGAVHFATYCDESNVAFHEGSPGVVFPVGDVSGGVRGEGADVDGGFVRFRAGEDVLACATAGTELSSDATNGAASSRDVFLFATWTAPATIVKARSHWSPYDRVGDVNADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9L0</accession>
    <name>C1N9L0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_43378</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064470.1">
        <property type="nucleotide sequence ID" value="XM_003064424.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9689742"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43378"/>
    <dbReference type="OrthoDB" id="10693203at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1244"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1457" mass="145943" checksum="0A2B1CBC9C33DD86" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9M5</accession>
    <name>C1N9M5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_54543</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064763.1">
        <property type="nucleotide sequence ID" value="XM_003064717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9M5"/>
    <dbReference type="GeneID" id="9690076"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54543"/>
    <dbReference type="OrthoDB" id="203682at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="4">
        <location>
            <begin position="92"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="23"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="338" mass="35809" checksum="D2CFFECDC0A2E2EA" modified="2009-05-26" version="1">MRACPSVAAAASRGVVVHHATARARSSPRVVLPASSRRGVAIARAPRADASGDGVVDAPSPSPSPSPSPPPLSLAEEEEEEEDPDAEARAALTRRLMALAAASSRGQQDTRDTRASVEDVVTELEFMNPTTDPASAIDGEWTLVYANVEAFRSSPFFWAFQDAIPGGEDLANGVFKFTAGLPVAGTAGPFGAIKQIVNLESGASHLITLVPVRPRELVSEVEMKIFDPFFGALSGISGVVVSAANVRVVDEETIAVAPRTTRIRNSNVGAGLLEGASYEYSFVYHAGPDATPFLPRGLTFSSPFALFVALDRPMKVHARHVIKPLINHITSRHVARQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA60</accession>
    <name>C1NA60_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_54773</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064851.1">
        <property type="nucleotide sequence ID" value="XM_003064805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA60"/>
    <dbReference type="STRING" id="564608.C1NA60"/>
    <dbReference type="GeneID" id="9690176"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54773"/>
    <dbReference type="OMA" id="WTKTAHT"/>
    <dbReference type="OrthoDB" id="495938at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11717">
        <property type="entry name" value="THUMP_THUMPD1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2300.10">
        <property type="entry name" value="THUMP superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040183">
        <property type="entry name" value="THUMPD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452">
        <property type="entry name" value="THUMP DOMAIN CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452:SF10">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143437">
        <property type="entry name" value="THUMP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="THUMP" evidence="3">
        <location>
            <begin position="125"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="260" mass="28502" checksum="81AFF0DFEC5B321C" modified="2009-05-26" version="1">MTSETHSVGMPPELDPHDTAPPPLPPWLKGFLVTSKNAADVKRAGEEVAKLCSDFWFKAAYDEQVPASMVGQPGVTAVPFDTAESLHVPGCKGTVFVALRPDNTTVDVRLLAKGLIEESDAVGGPDAKGEAWTKTAHTRRIIPIERIAPETDFDELAEKVISWHFPELPPEKRKDPLTTFRVHFEEHSPALHLKKLEIAKKIADLVPEDSYKVDLKHADLVILCVVAGGCAMMSVVEGYDDRMHHFTIHPEKQPASPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA89</accession>
    <name>C1NA89_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_45119</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064752.1">
        <property type="nucleotide sequence ID" value="XM_003064706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA89"/>
    <dbReference type="STRING" id="564608.C1NA89"/>
    <dbReference type="GeneID" id="9690193"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45119"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RGKNAMD"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="27"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="235"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH51086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="421" mass="46039" checksum="67BCBD25E8E67196" modified="2009-05-26" version="1">MKGSVPPNVLAATSAFQRPSPIQAQSWPIVLSGRDMVGIAATGSGKTLAFGLPALTQILSQARSRFRLRSPTTPPAKPGQPICLVLAPTRELAQQTARVFDEAGKSCNVRCVCVYGGAPKWEQKKQARSIHWSPYDPMREGGGCAVVVATPGRLRDFMNDGDVKLDRVTTLVLDEADRMLDLGFEPEIREIAGATRADRQTVMFSATWPMSIQGAFMRDPVKVRIGAEGLKASHSITQIVEVVEPNDKDSHLTRLLKKYCGGQTPTPRTLIFALYKKERQNWACVPIHGDMTQRDREESVAAFKDGSKPLLVATDVAARGLDIKGVEYVINYTFPLTTEDYVHRIGRTGRAGKTGIAHTLFTVHDKARAGELANVLREAGAEVPDALTNFGTHVKKKESKLYGAHFKDVDTSVKATKITFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA99</accession>
    <name>C1NA99_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_37198</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064758.1">
        <property type="nucleotide sequence ID" value="XM_003064712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA99"/>
    <dbReference type="STRING" id="564608.C1NA99"/>
    <dbReference type="GeneID" id="9690199"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37198"/>
    <dbReference type="eggNOG" id="KOG0895">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RHYESEN"/>
    <dbReference type="OrthoDB" id="47801at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004869">
        <property type="term" value="F:cysteine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23810">
        <property type="entry name" value="UBCc_BIRC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF39">
        <property type="entry name" value="BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="14"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="258" mass="28965" checksum="754F80AF801E691A" modified="2009-05-26" version="1">MSSDTSSDNGGSKKKQKRLAREVASLSEPGALPRELTGSIFVRHDVDRLDRMRAVVVGADGTPYDGGCFVFDVYFPANYPAVAPLVNLDTTGGGRARFNPNLYADGKVCLSLLGTWHGGSAEEKWDPERSSLSQVLVRRVRASHYCVQGLIMCEDPMYNEPGFDGIRGTPEGVNKSKEYDEDVRLNTARHAMVAHLRRPRRGVNDAIRTHFRLRRWRTMRTVLRWCEEASDETRRARLWDAAKELGGLLAALKDERDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRC8</accession>
    <name>C1KRC8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein uL2c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl2</name>
        <name evidence="9" type="ORF">MicpuC_chl27</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="9"/>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRC8"/>
    <dbReference type="STRING" id="564608.C1KRC8"/>
    <dbReference type="OMA" id="NQCWATI"/>
    <dbReference type="OrthoDB" id="563959at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000001">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000003">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_uL2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_uL2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_uL2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="8">
        <location>
            <begin position="42"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="7">
        <location>
            <begin position="124"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="222"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACO50760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="277" mass="30777" checksum="55058DF377F757CA" modified="2009-05-26" version="1">MALRFYKAYTPGTRHRSVSDCTELSKTRPEKSLTRSLHRAKGRNNRGVITCRHRGGGHKRLYRQIDFRRNKYDMNAEVRTIEYDPNRNARIALVQYEDGEKRYILQPTGLQVGDTIIASTSAPNAIGNALPLAAMPLGVQIHNIEVHPKKGGQLVRSAGGVAQLVAKEGDFVTVRLPSGEVRLLNNQCWATIGQVGNSEVMNLSMGKAGRSRWLGRRPTVRGSVMNPVDHPHGGGEGRCPVGRSQPMTPWGKPALGRKTRARKKYSDSLILRRRKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGV6</accession>
    <name>C1MGV6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_9258</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055386.1">
        <property type="nucleotide sequence ID" value="XM_003055340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGV6"/>
    <dbReference type="STRING" id="564608.C1MGV6"/>
    <dbReference type="GeneID" id="9680812"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9258"/>
    <dbReference type="eggNOG" id="ENOG502QT89">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HRDADWH"/>
    <dbReference type="OrthoDB" id="1415013at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009240">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04692">
        <property type="entry name" value="NUDIX_Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885:SF20">
        <property type="entry name" value="NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="86" mass="9830" checksum="9BF355F798D44685" modified="2009-05-26" version="1" fragment="single">FDIFRDGPMPTGETKPRALVHRDADWHRSVHVWLIDRATQKVALQKRSAKKDTFPNLWDISAAGHIESGHDSRDTAVRELEEELGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH54</accession>
    <name>C1MH54_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_13387</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054892.1">
        <property type="nucleotide sequence ID" value="XM_003054846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH54"/>
    <dbReference type="GeneID" id="9680218"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13387"/>
    <dbReference type="eggNOG" id="ENOG502SKEH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TPPYDQT"/>
    <dbReference type="OrthoDB" id="2016436at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144010">
        <property type="entry name" value="CofE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="527" mass="57116" checksum="83D21D63D3B0CBB3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH75</accession>
    <name>C1MH75_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_13467</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055445.1">
        <property type="nucleotide sequence ID" value="XM_003055399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH75"/>
    <dbReference type="STRING" id="564608.C1MH75"/>
    <dbReference type="GeneID" id="9681186"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13467"/>
    <dbReference type="eggNOG" id="ENOG502QR3G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IVHCGRI"/>
    <dbReference type="OrthoDB" id="784548at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000041">
        <property type="entry name" value="Ribosomal RNA small subunit methyltransferase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00138">
        <property type="entry name" value="rsmG_gidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003078">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="214" mass="22104" checksum="2525F507E6896B82" modified="2009-05-26" version="1">MNLTGATTVDEVLSRHVADSLALIPPIEAALASSTTSSSPSHTPRILDVGSGAGFPGVALAIARPRWEVTLLDTLQKRVAFLDAAAEECGATNVKTLWSRAEDAGKVGSEHREAYDIVTARAVAELRTLAELCVPLVRVGGSWVAAKNSTTSTAAETAAAAAAVELLGGAPLVAVEVQSEGPDGEMRTAVVSAKARETPGKYPRRAGLANKRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHS3</accession>
    <name>C1MHS3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_50303</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS37 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055543.1">
        <property type="nucleotide sequence ID" value="XM_003055497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHS3"/>
    <dbReference type="STRING" id="564608.C1MHS3"/>
    <dbReference type="GeneID" id="9681076"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50303"/>
    <dbReference type="OMA" id="ECEAMDE"/>
    <dbReference type="OrthoDB" id="10260857at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009851">
        <property type="entry name" value="Mod_r"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678:SF2">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07200">
        <property type="entry name" value="Mod_r"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51314">
        <property type="entry name" value="VPS37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS37 C-terminal" evidence="9">
        <location>
            <begin position="175"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="175"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="261"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="276" mass="30307" checksum="9818341D712DE51F" modified="2009-05-26" version="1">MGGLFGNKTPYSDPRRPADRAGSHAGASAAAAQFEQMHLRDQNARRAHPHGTTSHATGAAPVGGVSGGGSRVLVGTARNFPSLLRLTNEELRTLLTDQTAFATFLHDTEEAKDARAFTRDLRNEIAGMCAVNIEMADEARDLKAQLKIIGSCDQARSISHWFPYDRVGVVNAPVLAEHEEVRKRAEEVMRNYDLDTVLDALRRRAAKLDEECEAMDEKLQSGKMTADEFCKEYPALRQRYHEDALKAAIVQPALESRRGGGPPPPPPPPPPPHYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI23</accession>
    <name>C1MI23_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50406</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055592.1">
        <property type="nucleotide sequence ID" value="XM_003055546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI23"/>
    <dbReference type="STRING" id="564608.C1MI23"/>
    <dbReference type="GeneID" id="9681057"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50406"/>
    <dbReference type="eggNOG" id="KOG0907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000245">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="44"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="180" mass="19728" checksum="04D7EB5E20582673" modified="2009-05-26" version="1">MVKIVESKEEFEALKTGDKPVPGHSRDRARRARDLARVARLASPSNTALAPLGAFKHARDANKRRGPIERSPRLAHARRLRPSVHSIHRAKLVAQVLVDFTASWCGPCKMIAPFFEELAAKYPGVVFVKVDVDDLDDVAAECGISAMPTFQLYSNGVKVQELTGADKDKLEALAKSADDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI46</accession>
    <name>C1MI46_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_50433</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGC family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055066.1">
        <property type="nucleotide sequence ID" value="XM_003055020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI46"/>
    <dbReference type="STRING" id="564608.C1MI46"/>
    <dbReference type="GeneID" id="9681171"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50433"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009450">
        <property type="entry name" value="Plno_GlcNAc_GPI2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12982">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN, CLASS C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12982:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06432">
        <property type="entry name" value="GPI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="336" mass="34640" checksum="97D7D409E56CB084" modified="2009-05-26" version="1">MSLSEEVRTRSSSVASTSDLEETPPKWERILYRCAARPSFSDDDDPPRPPASSSSRSVRPPSDDPRQPASIDDRRPPPPPPVPSPPPYRRQPYPDNHTDDSFLERVVVNGRVIPRSLSAATSVARVVSAQLACAVLASVAVAHVHAGRVAPARVLAANVASTACALLGAMATRGPRMGLRVAGARIAAAAPALAAALAASSAPFRAAAVAAVSTDVAVAGAIAALFVHVLSFDYARRERGGGGGGGGGGGDDFDAATPPRNGVSLSAAALASALLCSRLDSTAAARACALTSVTMFATVQGMRSDARRASTRAFRAEVRPIHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI70</accession>
    <name>C1MI70_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46303</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055617.1">
        <property type="nucleotide sequence ID" value="XM_003055571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI70"/>
    <dbReference type="STRING" id="564608.C1MI70"/>
    <dbReference type="GeneID" id="9680820"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46303"/>
    <dbReference type="eggNOG" id="KOG0266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CVIPHGE"/>
    <dbReference type="OrthoDB" id="6363363at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990756">
        <property type="term" value="F:ubiquitin-like ligase-substrate adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052596">
        <property type="entry name" value="AMBRA1_autophagy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874:SF1">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="106"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="590"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="611" mass="64121" checksum="AA06C188FDC81913" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MID9</accession>
    <name>C1MID9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_8995</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055113.1">
        <property type="nucleotide sequence ID" value="XM_003055067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MID9"/>
    <dbReference type="STRING" id="564608.C1MID9"/>
    <dbReference type="GeneID" id="9680387"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8995"/>
    <dbReference type="eggNOG" id="KOG0907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CKESAPV"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016671">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010190">
        <property type="term" value="P:cytochrome b6f complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044241">
        <property type="entry name" value="TxlA/HCF164"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47353">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN HCF164, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47353:SF1">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN HCF164, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="106" mass="11754" checksum="2F8B023C1315AC9A" modified="2009-05-26" version="1" fragment="single">ALRNGRPTVLEFYADWCEVCKESAPVVYDVEKKFGEKINFVMLNIDNTKWGGEIDQYGVDGIPHIVFLDDEGKSEGMVVGKFPKQVLEANVAALSEGKTSLPYAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MII7</accession>
    <name>C1MII7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_50581</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055674.1">
        <property type="nucleotide sequence ID" value="XM_003055628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MII7"/>
    <dbReference type="STRING" id="564608.C1MII7"/>
    <dbReference type="GeneID" id="9681005"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50581"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4400">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YVHNLSW"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF3">
        <property type="entry name" value="FI21236P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="43"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="6">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="6">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="6">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="116"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="168"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="259"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="310" mass="32897" checksum="A6FD33E99C7E3808" modified="2009-05-26" version="1">MGYDDRRGPSRGGGGGGGRHNPYGRDDRGRDDYEEEVIEISTNRLYVHNLSWRVSWQDLKDHFRQAGEVIHAKIMTEGPGGRSKGCGIVEMGTVDEAANAIEMLNDTDLNGRNILIREDREDNGGRGGGGGGGGFRSDRGFAGRGGGPGDGDRCNKCGGIGHWARDCPSRIDVGRGGGGGRFRSDHDDRGRDHRGERRERPPRREPGADDTCNRCGKTGHWARDCPEPRNDGKTGARGPGADDKCNICGELGHWARDCPNKDKFPKRGGGGGGGDGGDEGAGDAAALDNDLEEYKAAAPAGDADGDVAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ64</accession>
    <name>C1MJ64_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50826</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055779.1">
        <property type="nucleotide sequence ID" value="XM_003055733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ64"/>
    <dbReference type="GeneID" id="9681210"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50826"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18143">
        <property type="entry name" value="HAD_SAK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH61031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="576" mass="60972" checksum="A605BEDCE42CC076" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJC4</accession>
    <name>C1MJC4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_61884</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055807.1">
        <property type="nucleotide sequence ID" value="XM_003055761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJC4"/>
    <dbReference type="STRING" id="564608.C1MJC4"/>
    <dbReference type="GeneID" id="9680488"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61884"/>
    <dbReference type="eggNOG" id="KOG1851">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="17907at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016504">
        <property type="term" value="F:peptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035309">
        <property type="entry name" value="PSME4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170:SF3">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH61059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="563" mass="59916" checksum="4A2F4CFD92096A9B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK11</accession>
    <name>C1MK11_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_31295</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056308.1">
        <property type="nucleotide sequence ID" value="XM_003056262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK11"/>
    <dbReference type="STRING" id="564608.C1MK11"/>
    <dbReference type="GeneID" id="9681912"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31295"/>
    <dbReference type="eggNOG" id="KOG2581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AKVYFYF"/>
    <dbReference type="OrthoDB" id="1713558at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013586">
        <property type="entry name" value="PSMD3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057985">
        <property type="entry name" value="TPR_PSMD3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08375">
        <property type="entry name" value="Rpn3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25573">
        <property type="entry name" value="TPR_PSMD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="281"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="87"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="525" mass="58213" checksum="35B61E6E171D25FD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK13</accession>
    <name>C1MK13_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_13860</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWF11 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056310.1">
        <property type="nucleotide sequence ID" value="XM_003056264.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MK13"/>
    <dbReference type="GeneID" id="9681661"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13860"/>
    <dbReference type="eggNOG" id="KOG1806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YRVWLDC"/>
    <dbReference type="OrthoDB" id="1879at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17935">
        <property type="entry name" value="EEXXQc_AQR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002863">
        <property type="entry name" value="Pre-mRNA-splicing factor cwf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003210">
        <property type="entry name" value="RNA helicase aquarius"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048966">
        <property type="entry name" value="Aquarius_b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048967">
        <property type="entry name" value="Aquarius_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032174">
        <property type="entry name" value="Aquarius_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026300">
        <property type="entry name" value="CWF11_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF5">
        <property type="entry name" value="RNA HELICASE AQUARIUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16399">
        <property type="entry name" value="Aquarius_N_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21143">
        <property type="entry name" value="Aquarius_N_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21144">
        <property type="entry name" value="Aquarius_N_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038901">
        <property type="entry name" value="AQR_cwf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="1" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA helicase aquarius N-terminal" evidence="4">
        <location>
            <begin position="30"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius beta-barrel" evidence="5">
        <location>
            <begin position="470"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius insertion" evidence="6">
        <location>
            <begin position="702"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="811"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="1117"/>
            <end position="1308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR038901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1383" mass="157754" checksum="D104DCD74035B5FD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK73</accession>
    <name>C1MK73_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_4607</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055949.1">
        <property type="nucleotide sequence ID" value="XM_003055903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK73"/>
    <dbReference type="STRING" id="564608.C1MK73"/>
    <dbReference type="GeneID" id="9681671"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4607"/>
    <dbReference type="eggNOG" id="KOG0279">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="59941at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040066">
        <property type="entry name" value="WDR31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19869">
        <property type="entry name" value="SPERMATID WD-REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19869:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="90"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="238" mass="25604" checksum="648D2C8C4CE73499" modified="2009-05-26" version="1" fragment="single">PAHGGNSVSSICSGGPGVLITGGHDGSAAMWQWCVDGDAGDVVTHRWSEHPGPVTRVAHLPLAGRVLTGCRDGVVRAWPSFDDDTPALTLCGHTLTVTGLDGLEELSAACSGSRDYTLRHWDLHTAKCVQMAAVSRNVVTSLRRCPGECTVVQSSEDLKIRTWDVRDFSSGPCQTLEGHVNIPQCIDVSPCGRYILSCSNGFEGSGGSEVRFWDRRTGKVLQEWRDHDMSVNGCVFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKC5</accession>
    <name>C1MKC5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_64311</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056363.1">
        <property type="nucleotide sequence ID" value="XM_003056317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKC5"/>
    <dbReference type="GeneID" id="9681326"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64311"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="106" mass="12136" checksum="8CCB68042D7FBC9A" modified="2009-05-26" version="1">MTTIKRKIEEKRTVLPVLIMRQMSGRLADLRQFQGISKIGILTQGVSTNTSLEIVDFLDFQQISLLNRCRQLPEIRARLENATKKLSSFLTQIDSQGLFEITAKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKE3</accession>
    <name>C1MKE3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_64346</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056370.1">
        <property type="nucleotide sequence ID" value="XM_003056324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKE3"/>
    <dbReference type="GeneID" id="9681491"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64346"/>
    <dbReference type="OrthoDB" id="498474at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="168" mass="18504" checksum="B84CD3589AED9264" modified="2009-05-26" version="1">MPVERILNPLNGVERAISVLSTSSALRSTGMVAQEFAGAEWWVQDVGPEENPKGFHTDCNFQTKTGNARNENVYQGNACRCAVFHPTVASVLYLVNNGGATAIFGQAKQFFSDYSILQPRLPTEVCIVNPKRNRVLVFEGDRYHAVLHPASSYEDSSCQRVRSSLALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKH2</accession>
    <name>C1MKH2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone H1 linker protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_64409</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the histone H1/H5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055997.1">
        <property type="nucleotide sequence ID" value="XM_003055951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKH2"/>
    <dbReference type="STRING" id="564608.C1MKH2"/>
    <dbReference type="GeneID" id="9681698"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64409"/>
    <dbReference type="eggNOG" id="ENOG502RZJS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HKEEART"/>
    <dbReference type="OrthoDB" id="1110759at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031492">
        <property type="term" value="F:nucleosomal DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467:SF36">
        <property type="entry name" value="HISTONE 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="8">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="75"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="79"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="138" mass="15019" checksum="65BCB6AC16145CD6" modified="2009-05-26" version="1">MPPKMSAHPKYEDMVKAAILALKDKKGSSVPAIAKYLAANFKLPANFKKILSTQLKNLVKAGKLLKIKASYKLGDALKKAPKKPKKKAAKKPKKKAAKKPKKKAAKKPKKAKKAAAKKAVKKPKKAKKATKKAVSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKK6</accession>
    <name>C1MKK6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_64469</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056011.1">
        <property type="nucleotide sequence ID" value="XM_003055965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKK6"/>
    <dbReference type="STRING" id="564608.C1MKK6"/>
    <dbReference type="GeneID" id="9681962"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64469"/>
    <dbReference type="eggNOG" id="KOG1974">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="514214at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031298">
        <property type="term" value="C:replication fork protection complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044998">
        <property type="entry name" value="Timeless"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006906">
        <property type="entry name" value="Timeless_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940:SF4">
        <property type="entry name" value="PROTEIN TIMELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940">
        <property type="entry name" value="TIMEOUT/TIMELESS-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04821">
        <property type="entry name" value="TIMELESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Timeless N-terminal" evidence="4">
        <location>
            <begin position="31"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="318" mass="36440" checksum="253B7D4A12D5CB23" modified="2009-05-26" version="1">MHLEKEVFDIAHLQSLATSLGKRQKHNEDCVYVRDPQCHETLQDILRFLRRDTTSSRSIMLLLHGWNLVEKDLIPLLLNYRGEASVFLDSIKLLVFLTLPADQESSSYAQQRRCILNTLTALLQSQEIIPVLFSALLVSLERYEVNQLRSNDEDAKVIQLFLTLIRNLLAGTDYRVAGSRGQDHVVLKEKLLTVLFDLQFPALLSQMAKDARKNPFTEESALLVEIFDLLFLDQNPSLLALFFDQQRREAPSVKAAKNSQSWTTCQQDRHKHVRHSRFGSRVVSASSGDTVNSKRTGFRSFLLTRRSYFGKVVSMNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKK9</accession>
    <name>C1MKK9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_70267</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056014.1">
        <property type="nucleotide sequence ID" value="XM_003055968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKK9"/>
    <dbReference type="STRING" id="564608.C1MKK9"/>
    <dbReference type="GeneID" id="9681345"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70267"/>
    <dbReference type="eggNOG" id="KOG3326">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="284292at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.250:FF:000004">
        <property type="entry name" value="Succinate dehydrogenase assembly factor 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.250">
        <property type="entry name" value="Flavinator of succinate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005631">
        <property type="entry name" value="SDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036714">
        <property type="entry name" value="SDH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12469">
        <property type="entry name" value="PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12469:SF2">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03937">
        <property type="entry name" value="Sdh5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109910">
        <property type="entry name" value="YgfY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="20003" checksum="F60652C060961F7E" modified="2009-05-26" version="1">MLLIFRSAAPILGHASVALSCYNRLQSRNSDVQKPLFCSYSEKSQLHTDSVTPSYAERKHSKKLFNRLLYRAKQRGFLELDILVGKWAQRHLINRSEEFMASFSEVLDEENPELFKWLTGQEYPPSRLANNLAFISLQVHVITIMNQKSHRGARAEAGHSWLRGWSDGTTKQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML20</accession>
    <name>C1ML20_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55547</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056097.1">
        <property type="nucleotide sequence ID" value="XM_003056051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML20"/>
    <dbReference type="STRING" id="564608.C1ML20"/>
    <dbReference type="GeneID" id="9681996"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55547"/>
    <dbReference type="OrthoDB" id="340681at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006886">
        <property type="entry name" value="RNA_pol_III_Rpc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04801">
        <property type="entry name" value="RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="238" mass="27066" checksum="55D8F92BE66F9D32" modified="2009-05-26" version="1">MDGSENRCPKVLNRRNTMEKRIPIYFSSVVQDKKLCVLQYPLRSFERPFAEGDIEEVRFKPISNKLEVELRAMRDTNEDDQVQPPSGTSGPCILASTEAPINDYYYVAEIRSGALYLSPLKNVYQMRPSMSILDKTDERKFEQEKMSESDPAAQQAGHDDLDSEVGYVPATTGGGTGNQKLLPLQVQVKRRETDRQTEVRLHSHAHLKHVEESELWTVLEPRFTLSATCSDDPRGTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLL1</accession>
    <name>C1MLL1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_31943</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056186.1">
        <property type="nucleotide sequence ID" value="XM_003056140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLL1"/>
    <dbReference type="STRING" id="564608.C1MLL1"/>
    <dbReference type="MEROPS" id="M67.A13"/>
    <dbReference type="GeneID" id="9681802"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31943"/>
    <dbReference type="eggNOG" id="KOG1554">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="INISMQM"/>
    <dbReference type="OrthoDB" id="10266268at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000003">
        <property type="entry name" value="COP9 signalosome complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040961">
        <property type="entry name" value="CSN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18323">
        <property type="entry name" value="CSN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0736">Signalosome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="8">
        <location>
            <begin position="38"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="37041" checksum="791BA15C7875554A" modified="2009-05-26" version="1">MQTEFNDGDVLFRYDELQGTAIQQQKPWGRNPHFFKHVRITGNALIKMAKHCRSGGNLEVMGMLCGKTAGDTFLVLDCFALPVVGTETRVNAQAEAYEYMVSFVQARQQVGRREHVIGWYHSHPGYGCWMSGIDCSTQLLNQQYTEPFVALVIDPVRTCASGRVNVGAFRTFPLGYSPPDDTRLKYQTVPTNKIKDFGVHANQYYCLNTSFFKSSRVSAVLAAAWNNYWVNTLSSSPLHTNQTFVAGQITDIAEKVMLSDCLESPHQKKNSVCTSKVAAAQHCKLLLSAYDGSIISMEQTKGSASRALKESIFNFAVKPGKVLSNQGTLVRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM23</accession>
    <name>C1MM23_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_32377</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057320.1">
        <property type="nucleotide sequence ID" value="XM_003057274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM23"/>
    <dbReference type="STRING" id="564608.C1MM23"/>
    <dbReference type="GeneID" id="9682759"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32377"/>
    <dbReference type="eggNOG" id="KOG0747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TYFEMNV"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000304">
        <property type="entry name" value="UDP-glucose 4,6-dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="6">
        <location>
            <begin position="29"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="5">
        <location>
            <begin position="400"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="691" mass="76439" checksum="7C3A01AD69E9931D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMC3</accession>
    <name>C1MMC3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56475</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056906.1">
        <property type="nucleotide sequence ID" value="XM_003056860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMC3"/>
    <dbReference type="STRING" id="564608.C1MMC3"/>
    <dbReference type="GeneID" id="9682345"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56475"/>
    <dbReference type="eggNOG" id="ENOG502QUFE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PCCTAKS"/>
    <dbReference type="OrthoDB" id="206598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13369">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13369:SF0">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="125"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="428" mass="44854" checksum="53D08318BA4B7926" modified="2009-05-26" version="1">MGNGSRSRRLREAMAAGTATAEAGDDPNAARRAQKKAHKARQRRRKNERRHDAVRAIVSRLAPPASGDAFTPLEKTRAWDGAPPIDWSTMRASCDPAKMAYDGDEASASAANAASAAVVTVRAKRKRWQVESFAVVLRELQREHERGGGGGNGGDDARRLKVVDFGAGSGNLTLPLAAAFPSMDFVAVEMKRRSADLVSQRAAAAGLSNVTVLCGMIERAEIGPFDVGVALHACGNATDHSIARCVRANAAFLVSPCCIGKLKFSIAGGSSFSANVVDYKDTALGSRPEREAGAGAAATKASEDARNDDVVVCPPVEAITHPRSRWLSTQLASENEFAALAAAADTGHAAGVPGGDAPSDDVLDIGRAAKTQVELDRAEGAREAGYVVRTLAVLNAAEAPPNKSDLIVGARRGRWRDAFERLAVAVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMR7</accession>
    <name>C1MMR7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_56629</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056975.1">
        <property type="nucleotide sequence ID" value="XM_003056929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMR7"/>
    <dbReference type="STRING" id="564608.C1MMR7"/>
    <dbReference type="GeneID" id="9682414"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56629"/>
    <dbReference type="eggNOG" id="KOG4640">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DKNMLAP"/>
    <dbReference type="OrthoDB" id="2110451at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024789">
        <property type="entry name" value="APC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024790">
        <property type="entry name" value="APC4_long_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260">
        <property type="entry name" value="ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260:SF0">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12896">
        <property type="entry name" value="ANAPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="8">
        <location>
            <begin position="31"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="68"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4 long" evidence="9">
        <location>
            <begin position="285"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="148"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="525"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="543"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="861" mass="88747" checksum="61604F96DA2FF859" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMS7</accession>
    <name>C1MMS7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56641</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057456.1">
        <property type="nucleotide sequence ID" value="XM_003057410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMS7"/>
    <dbReference type="GeneID" id="9682421"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56641"/>
    <dbReference type="OMA" id="EASECAN"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="293" mass="30356" checksum="79E56AAE480F9C79" modified="2009-05-26" version="1">MPSFKTSDGSPFPILGERLVVGHCDVSGAGVRACLGLKPGDFDREGAWSRVAVELTGVPPRRRAIAGEGVGESDDGGGEDDDDDDDDAPRGVVFTPGGARVADAADADAADAASAAPMTLTTFDDGVASVLAVNEIVRPGEEAAFAAAVHDLLTDDATRGNCEGVVVVAALRMNAPKEGRIFQNVVNGAAPLLIDFQPAELPPETKINDPVVAALAHAMTAGGHEMHLITTHGYRVAKLGTKDEKEASECANRVGGAVAAALECRFRKTGLEATRAWTSDAAAPKEKTDHMYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN50</accession>
    <name>C1MN50_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_62682</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057043.1">
        <property type="nucleotide sequence ID" value="XM_003056997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN50"/>
    <dbReference type="GeneID" id="9682957"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62682"/>
    <dbReference type="OMA" id="DMAWDYR"/>
    <dbReference type="OrthoDB" id="525787at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="624"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="672" mass="71368" checksum="18503F91A6C2BA29" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MND2</accession>
    <name>C1MND2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56874</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057083.1">
        <property type="nucleotide sequence ID" value="XM_003057037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MND2"/>
    <dbReference type="GeneID" id="9682522"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56874"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="92" mass="9935" checksum="3088788BB496AF7E" modified="2009-05-26" version="1">MTTPEEAPTVSTHPNPTTGSIVVTSQPGVVTVASTKRSAETLLDLLRERAARCPLPAVLGPVLFATYTSRHELKEACHRWSKGHAKECGIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNF0</accession>
    <name>C1MNF0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HVA22-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_9205</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056639.1">
        <property type="nucleotide sequence ID" value="XM_003056593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNF0"/>
    <dbReference type="STRING" id="564608.C1MNF0"/>
    <dbReference type="GeneID" id="9682533"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9205"/>
    <dbReference type="eggNOG" id="KOG1725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RKHITER"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="78" mass="9040" checksum="FC2D610340EFED30" modified="2009-05-26" version="1" fragment="single">YASYKAIESASKSDDTQWLTYWVVYAFLLIGESLSEYMLVWIPGYRYVKCALIFWLASPRFKGAAVLYDKVVKDALKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNV5</accession>
    <name>C1MNV5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_6532</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057178.1">
        <property type="nucleotide sequence ID" value="XM_003057132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNV5"/>
    <dbReference type="STRING" id="564608.C1MNV5"/>
    <dbReference type="GeneID" id="9682159"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6532"/>
    <dbReference type="eggNOG" id="KOG3071">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WTYFTST"/>
    <dbReference type="OrthoDB" id="434092at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF126">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH58823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="213" mass="24994" checksum="E40EA6FF14971CC7" modified="2009-05-26" version="1" fragment="single">VLYLGMCYFGPKIMAKRNAFDPKGFMLVYNAYQTAFNVATVALFVTELKRLSVDPWGGRLKWKNPESFRICLGIWLHYNNKYLELLDTVFMVVRKKTEQVSFLHVYHHCLLIWAWWLVCFTIKNNDCVDAYFGACMNAGIHVIMYSYYLMAALKIACPWKKYITQAQMLQFVICFAHAVFVLRDGHCPRVLPYSQMFVMANMLYLFGQFYVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPC8</accession>
    <name>C1MPC8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_56230</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056800.1">
        <property type="nucleotide sequence ID" value="XM_003056754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPC8"/>
    <dbReference type="STRING" id="564608.C1MPC8"/>
    <dbReference type="GeneID" id="9682239"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56230"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF130">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="253" mass="26921" checksum="EDE6795E2A58A073" modified="2009-05-26" version="1">MLASPYRVRGLSPGRIPRRPRPVFAASLPAVRSFGVDDEDEIVASLTEGNDALPPLVEVVTRVGEDRLKVVKPPGAEDLWDWYESKGQMEADPSWGKLWFTSRILASCVASCVESLPELRSKRVVEVGCGLGLAGLSAAMFGGSKSVIFCDREPLAIHCALSSAALNEVEVVAVDDVNNSSSGCRVAGALLDWSAPQTLSQPVDVVLGADCLYDPATAALLASACHALVAGDGHVVGKRSLKPRCRAEQRERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPE0</accession>
    <name>C1MPE0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_7535</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057267.1">
        <property type="nucleotide sequence ID" value="XM_003057221.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPE0"/>
    <dbReference type="STRING" id="564608.C1MPE0"/>
    <dbReference type="GeneID" id="9682706"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7535"/>
    <dbReference type="eggNOG" id="KOG3288">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TRCILVY"/>
    <dbReference type="OrthoDB" id="65596at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22793">
        <property type="entry name" value="OTU_plant_OTU1_2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057766">
        <property type="entry name" value="Znf-C2H2_OTU1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF0">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24560">
        <property type="entry name" value="zf-C2H2_OTU1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="7">
        <location>
            <begin position="2"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="202" mass="22388" checksum="AB11098564E691A1" modified="2009-05-26" version="1" fragment="single">VATRRVIDSDNSCLFNAVGYVMNRSLRDAPALRKVIADVVSGDAFTYNDGFLGKPNAEYCRWILESNHWGGAVELSILAKHFKREIAAYDIQTKRCDVYGQGEGYPERVMLLYDGLHYDAMVLTYEGAPHDMDITMFPSRGPAADAAGRKASKVVNEAHAARQFTDTANFTLRCLVCQKGLKGEKEALEHAKASGHSNFSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPR5</accession>
    <name>C1MPR5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_2525</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057629.1">
        <property type="nucleotide sequence ID" value="XM_003057583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPR5"/>
    <dbReference type="STRING" id="564608.C1MPR5"/>
    <dbReference type="GeneID" id="9683436"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2525"/>
    <dbReference type="eggNOG" id="KOG2227">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WPTDEVY"/>
    <dbReference type="OrthoDB" id="1926878at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08768">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016314">
        <property type="entry name" value="Cdc6/18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="WHD_Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001767">
        <property type="entry name" value="Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc6 C-terminal" evidence="5">
        <location>
            <begin position="347"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="437" mass="46970" checksum="99668979DE17D98E" modified="2009-05-26" version="1" fragment="single">SQWDPTDPGMVTQAKAVMHTSVAPGELKCREREHKEVMAAIHAALKHRKSSSMYVCGLPGTGKSLTVGEAEKAVRRWGDGSGRVGKLAKSERPIVAAVNCMALSEPRHVFARIIEALGGVSPAELARASADAGGNPENSDLSQLPERFKGRANDAAKPMVVVLLDEMDQLASKAQSILYELFGLPTLPGSRCVVVGVANNINLVEVTLPRLKMRGCEPEVVRFDAYDKDQLKLLLAQRLAKLPWECFEDAGLELCSRKVASATGDMRRALNICAVAVDLCAREAAAAAAEAEAEAEGVATEKTPAEAARESKPLVRISHVARAISLSFASPVVDTMRSLPQQQQMVLCAAVRLFRVGGGASRSRETKLGELHDKYSSLCKETAIKGMNSGQFSEVCAVLADQTLLRLGKGAEDRQRKVSLAVHEDDVTFALQGVKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPT3</accession>
    <name>C1MPT3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57025</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058006.1">
        <property type="nucleotide sequence ID" value="XM_003057960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPT3"/>
    <dbReference type="GeneID" id="9683051"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57025"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="172" mass="18101" checksum="C101A901C7D42048" modified="2009-05-26" version="1">MPHVALVPARLGAVARGDAPRRVRAVASARVEASSSKRAPSRGRAKSVSKQLSVIRRRLPPPAVARGRRSTATLSSADENDEAHDVEHAAPTPKKKKSEINITGMGSRYVEGEITWAAIAVQAALAVMALGAVGALVFTAPNKDSPQFQKRDRVENVRLGVVSDVNDAPGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPU8</accession>
    <name>C1MPU8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[histone H3]-lysine(4) N-trimethyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.354</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_57043</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60260"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.354"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60272"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60268"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="Rhea" id="RHEA-COMP:15543"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.1.1.354" evidence="2"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057648.1">
        <property type="nucleotide sequence ID" value="XM_003057602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPU8"/>
    <dbReference type="STRING" id="564608.C1MPU8"/>
    <dbReference type="GeneID" id="9683096"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57043"/>
    <dbReference type="eggNOG" id="KOG1080">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140999">
        <property type="term" value="F:histone H3K4 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044570">
        <property type="entry name" value="Set1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ARID" evidence="14">
        <location>
            <begin position="286"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="12">
        <location>
            <begin position="815"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="13">
        <location>
            <begin position="997"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="258"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="423"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="525"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="444"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="529"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH57599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1029" mass="108711" checksum="1B3EEBEF66D9B486" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ70</accession>
    <name>C1MQ70_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_39273</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058076.1">
        <property type="nucleotide sequence ID" value="XM_003058030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ70"/>
    <dbReference type="STRING" id="564608.C1MQ70"/>
    <dbReference type="GeneID" id="9683144"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39273"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YSGFHGR"/>
    <dbReference type="OrthoDB" id="4255at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12937">
        <property type="entry name" value="GUCT_RH7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059027">
        <property type="entry name" value="DD_DDX21-DDX50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050547">
        <property type="entry name" value="DEAD_box_RNA_helicases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012562">
        <property type="entry name" value="GUCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963:SF8">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26142">
        <property type="entry name" value="DD_DDX21-DDX50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08152">
        <property type="entry name" value="GUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="158"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="371"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="680"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="79"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH58027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="748" mass="79325" checksum="21A8CFD0335998B2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQV5</accession>
    <name>C1MQV5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57426</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057821.1">
        <property type="nucleotide sequence ID" value="XM_003057775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQV5"/>
    <dbReference type="STRING" id="564608.C1MQV5"/>
    <dbReference type="GeneID" id="9683634"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57426"/>
    <dbReference type="eggNOG" id="KOG3290">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PDSDQQT"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF46">
        <property type="entry name" value="PHYTANOYL-COA HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="283" mass="32030" checksum="C78CA1FA83826992" modified="2009-05-26" version="1">MPGIDGDAYVVTPEQIEAFERDGYVHLPNVLTEDEMREVEEPAMRFIRGEVVPEGKDLCDMSGATDRTPDEYTVFNAMLPRRYMPSMRGNIFERRTASIATQLQRGKNMAIDYDQLLAKRPSTSDSIFAWHQDMAYWPPLEEDPSTCTCWIAIDDSTVENGCMRFLPGSGMEKELRAHAPVKLKGGDRADDESSHALCTTLTAEDETRVRLVPIKRGDITVHDERVVHGSGPNGSDGWRRAYVLAYRTKDVVDEERRLGFTHSHNDAYNWDAFHAWQEKAASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQZ9</accession>
    <name>C1MQZ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_16474</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058219.1">
        <property type="nucleotide sequence ID" value="XM_003058173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQZ9"/>
    <dbReference type="STRING" id="564608.C1MQZ9"/>
    <dbReference type="GeneID" id="9683280"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16474"/>
    <dbReference type="eggNOG" id="KOG2877">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WTISPCC"/>
    <dbReference type="OrthoDB" id="196717at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014472">
        <property type="entry name" value="CHOPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414:SF77">
        <property type="entry name" value="CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414">
        <property type="entry name" value="ETHANOLAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="167" mass="18386" checksum="8211C61901308192" modified="2009-05-26" version="1" fragment="single">MWTISPCCAEKNPGRPHARASAVRCAQVRSYKYTSPNDTICEAAFLHPMWRDLLVPMCPRWLAPNLITFAGLICAVIAYAMMMHHSPDLNGDAEPWVYVACVVLLFIYQTCDGMDGHQARRTGGGSPLGEVVDHGADALVSCIYGVFLCDTFGASWTENRLFVIGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR12</accession>
    <name>C1MR12_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_67550</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057847.1">
        <property type="nucleotide sequence ID" value="XM_003057801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR12"/>
    <dbReference type="STRING" id="564608.C1MR12"/>
    <dbReference type="GeneID" id="9683665"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67550"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="86" mass="9476" checksum="D04FD871180E1343" modified="2009-05-26" version="1">MGLAHQAGLPFAQQYLKLSATDMQRYGIVAYFPWSLKPVFGMLSDVVPIAGTTSGITRWCSSTSKSPSWTCSRKGSTRRRCGSSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRP6</accession>
    <name>C1MRP6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GrpE protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_70842</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058911.1">
        <property type="nucleotide sequence ID" value="XM_003058865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRP6"/>
    <dbReference type="STRING" id="564608.C1MRP6"/>
    <dbReference type="GeneID" id="9683984"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70842"/>
    <dbReference type="eggNOG" id="KOG3003">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IMKGLHV"/>
    <dbReference type="OrthoDB" id="201635at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.22.10:FF:000001">
        <property type="entry name" value="Protein GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF40">
        <property type="entry name" value="CELL CYCLE AND APOPTOSIS REGULATOR PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="59"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH57366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="303" mass="33146" checksum="A80070B5D38D857D" modified="2009-05-26" version="1">MVFTTLALGAKAVAPRANVGRESTKGVPIRRQTPTPAFASKSRNERCLAKIPTVRKSSSRLIVRAAGGEGEEDDEENQRREAEAEVEVVDDDEDEDEDDEDEGSAPPPPSKCEELIAKLEESMDAPELAELAAEVKAIETAFKDLQAANVGLEDQTGALKDQYLRLNADFDNFKKRTIKEKEQLATNAKSRVFEAMLPALDNFDLAKANLKTENEGEEKIAKSYEGLVDGLMTILSAQGLSTVAGVGSPFDPNFHEAIMREESEEHPEDTISEEFRKGYKMGEDQLVRAAMVKVSSGPPASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS45</accession>
    <name>C1MS45_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58343</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058622.1">
        <property type="nucleotide sequence ID" value="XM_003058576.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MS45"/>
    <dbReference type="GeneID" id="9684061"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58343"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CADEREI"/>
    <dbReference type="OrthoDB" id="10250130at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244">
        <property type="entry name" value="KELCH REPEAT DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="863"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1203"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1282"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="709"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="727"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="770"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1215"/>
            <end position="1224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1317" mass="135724" checksum="00D8C0E81CC82F76" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS47</accession>
    <name>C1MS47_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58345</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058984.1">
        <property type="nucleotide sequence ID" value="XM_003058938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS47"/>
    <dbReference type="GeneID" id="9684423"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58345"/>
    <dbReference type="OrthoDB" id="88410at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="49" mass="5652" checksum="12277E37F2021429" modified="2009-05-26" version="1">MCSRTTCGKCGKPTWVRVPRRMHIEQALRGVPEEDRCQCPRKCRMCAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSB3</accession>
    <name>C1MSB3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_2397</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058651.1">
        <property type="nucleotide sequence ID" value="XM_003058605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSB3"/>
    <dbReference type="STRING" id="564608.C1MSB3"/>
    <dbReference type="GeneID" id="9684461"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_2397"/>
    <dbReference type="eggNOG" id="KOG0239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IFQERQG"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF45">
        <property type="entry name" value="PROTEIN CLARET SEGREGATIONAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="6">
        <location>
            <begin position="25"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="103"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="348" mass="37715" checksum="E2A8D80AEB1BB296" modified="2009-05-26" version="1" fragment="single">LERQLMDADDLRRAMHNQIQELRGNVRVFARMRPPKAGEEAHAAVKHVDKDSMSVVDRLGDDQCFSFDRAFGPDATQSDVFEEVSQLVQSALDGYKVCLFSYGQTGSGKTHTMLGAGDGDNAGIIPRAVQKVLETAENLKAKGYEYAMEASYVEIYNEQIRDLLRPGSYHSEKHAIVANPKGGCPEVSGVERERVASVAHAATLVRRAAAARAVEATQMNAQSSRSHTLFLLYITGTHRASGQQLSGCLNLVDLAGSERTARSGAEGQRMKEACAINKSLSSLGDVFMSIGRGDKHVPYRNSKLTHLLAPCLGGDGKTMMLVNVAPEPESAEESMCSLRFAAQVNAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSS6</accession>
    <name>C1MSS6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chlorophyll synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CHLG</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_33362</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058729.1">
        <property type="nucleotide sequence ID" value="XM_003058683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSS6"/>
    <dbReference type="STRING" id="564608.C1MSS6"/>
    <dbReference type="GeneID" id="9683828"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33362"/>
    <dbReference type="eggNOG" id="ENOG502QQMP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QDMYFLR"/>
    <dbReference type="OrthoDB" id="434972at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046408">
        <property type="term" value="F:chlorophyll synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13958">
        <property type="entry name" value="PT_UbiA_chlorophyll"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006372">
        <property type="entry name" value="Chl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011799">
        <property type="entry name" value="ChlG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02056">
        <property type="entry name" value="ChlG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01476">
        <property type="entry name" value="chlor_syn_BchG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005742">
        <property type="entry name" value="PRK07566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="361" mass="39401" checksum="6208387D8591F3BA" modified="2009-05-26" version="1">MSSPVSSGGFVPTPVSSSKRSSFVVRASPDGEAAKKAGEENEESGSNIRQLLGIRGGEQTTDIWKIRLQLTKPVTWVPLIWGVLCGAAASGHFTWTFENVGKSMLCMFMSGPLLTGYTQTINDWYDREIDAINEPNRPIPSGAISEFDVQVQMYALLLGGWAAAWTLDQWCEHDWPVVTVLVLFGSWVSYIYSAPPLKLKQEGWRGNYALGASYIALPWWAGQAVFGELSLDVMVLTVLYSIAGLGIAIVNDFKSIEGDRQCGLMSLPVAFGVEKAKWICVGSIDATQLAVAGYLRTIGEVGYSNALLALIFPQIFFQFKFFLPDPVKNDVKYQASAQPFLVFGLLTTGLAWGHHINAIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MST7</accession>
    <name>C1MST7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chloroplast envelope protein translocase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TIC55-4</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_47223</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058736.1">
        <property type="nucleotide sequence ID" value="XM_003058690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MST7"/>
    <dbReference type="GeneID" id="9683848"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47223"/>
    <dbReference type="eggNOG" id="ENOG502S06W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03467">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054716">
        <property type="entry name" value="Sol_Rieske_ferrdox_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21496">
        <property type="entry name" value="FERREDOXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21496:SF0">
        <property type="entry name" value="RIESKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22543">
        <property type="entry name" value="Rieske_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="7" id="KW-0946">Virion</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="76"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="227" mass="24681" checksum="DC4869BC51F57A01" modified="2009-05-26" version="1">MTSLWCAAGSAPSASRRISRKMLPASFMPRSVGVRAFAPTHSPSRGRVVLARRALHPHSPHTTADPITPDGPRPFVKVAELAELSAHGARSHVHLGGRHVSLINWRGDVHALDSLCYHAGGPLAVGEIEDVDGRACVSCPWHLYKIELETGEKLYGATTWDPEKGALVPDGTKSVGVRQRVHDVERRDDGWYVRLRLDGSVESDKYATKDVPGISGARRVRVPIEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSV5</accession>
    <name>C1MSV5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_57838</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058388.1">
        <property type="nucleotide sequence ID" value="XM_003058342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSV5"/>
    <dbReference type="STRING" id="564608.C1MSV5"/>
    <dbReference type="GeneID" id="9684186"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57838"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ASYRILW"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="528"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="559"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="595"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="603"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="624" mass="67843" checksum="37AF3D856260B675" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSV6</accession>
    <name>C1MSV6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_47235</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. TRA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058747.1">
        <property type="nucleotide sequence ID" value="XM_003058701.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MSV6"/>
    <dbReference type="GeneID" id="9683835"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47235"/>
    <dbReference type="eggNOG" id="KOG0889">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CLDLYGQ"/>
    <dbReference type="OrthoDB" id="5570127at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05163">
        <property type="entry name" value="PIKK_TRRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046807">
        <property type="entry name" value="Tra1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046805">
        <property type="entry name" value="Tra1_ring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF1">
        <property type="entry name" value="TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20175">
        <property type="entry name" value="Tra1_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20206">
        <property type="entry name" value="Tra1_ring"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAT" evidence="4">
        <location>
            <begin position="3163"/>
            <end position="3730"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="3">
        <location>
            <begin position="3976"/>
            <end position="4297"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="5">
        <location>
            <begin position="4311"/>
            <end position="4343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="470"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1053"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1159"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1285"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2307"/>
            <end position="2383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2645"/>
            <end position="2665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2768"/>
            <end position="2890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3027"/>
            <end position="3054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="493"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="508"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1053"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1181"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1200"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1286"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1347"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1374"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1389"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2313"/>
            <end position="2329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2339"/>
            <end position="2363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2374"/>
            <end position="2383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2787"/>
            <end position="2797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2798"/>
            <end position="2809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2836"/>
            <end position="2848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="2875"/>
            <end position="2884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="3038"/>
            <end position="3048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="4343" mass="473579" checksum="FD9D2E94C6499572" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU68</accession>
    <name>C1MU68_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_69472</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059442.1">
        <property type="nucleotide sequence ID" value="XM_003059396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU68"/>
    <dbReference type="GeneID" id="9684882"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69472"/>
    <dbReference type="eggNOG" id="ENOG502S6VC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="497687at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="63"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="209" mass="22589" checksum="00A544A85558468C" modified="2009-05-26" version="1">MMDVDNFDHLAAGVSVTADGMVSKADFEAAILSAQEALRAKNAASQTMLQEASSAMRNAVTALSLSEQEVANLRVTVKELTEREVPGQEGARLKSERAALRAAQRRIDELSSSFRNLQSEIAHAQYEREKAAGERVRMPVASKFPVRIDPLLASRAVVVAQLVMLGYDYDDAEDAIDECGGVNDAGPALALLEARRVLHTSPHTTALAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUT1</accession>
    <name>C1MUT1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial tRNA import complex</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_58923</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRB/QCR7 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059247.1">
        <property type="nucleotide sequence ID" value="XM_003059201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUT1"/>
    <dbReference type="STRING" id="564608.C1MUT1"/>
    <dbReference type="GeneID" id="9684687"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58923"/>
    <dbReference type="eggNOG" id="KOG3440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QTALHWV"/>
    <dbReference type="OrthoDB" id="425749at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1090.10">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003197">
        <property type="entry name" value="QCR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036544">
        <property type="entry name" value="QCR7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02271">
        <property type="entry name" value="UCR_14kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81524">
        <property type="entry name" value="14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="121" mass="14149" checksum="F7EA38F8D47DEF69" modified="2009-05-26" version="1">MSKALKKMFEPAIAAFAKRYQGWVGAELSKYGLRYDDLLCDYDLDVAEALKRLPQEERDLRMQRLKRAMDLSMKHINLSKEEQAKQTPFLWYVTPVLREVEAERDERAALGTGQPYNRQIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUV5</accession>
    <name>C1MUV5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_18161</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059565.1">
        <property type="nucleotide sequence ID" value="XM_003059519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUV5"/>
    <dbReference type="GeneID" id="9685005"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18161"/>
    <dbReference type="eggNOG" id="KOG0463">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FRFIQRP"/>
    <dbReference type="OrthoDB" id="248233at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03694">
        <property type="entry name" value="GTPBP_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03708">
        <property type="entry name" value="GTPBP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000091">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="121"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="583" mass="64103" checksum="E882F40B65206182" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV28</accession>
    <name>C1MV28_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_59035</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059296.1">
        <property type="nucleotide sequence ID" value="XM_003059250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV28"/>
    <dbReference type="STRING" id="564608.C1MV28"/>
    <dbReference type="GeneID" id="9684736"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59035"/>
    <dbReference type="OMA" id="AMIMTEI"/>
    <dbReference type="OrthoDB" id="512447at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051581">
        <property type="entry name" value="Ca-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34524">
        <property type="entry name" value="CALCYPHOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34524:SF6">
        <property type="entry name" value="CALCYPHOSINE LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="10"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="91"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="4">
        <location>
            <begin position="201"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="323" mass="36761" checksum="CA8B63C51A279BC4" modified="2009-05-26" version="1">MPGDARKACFKEDVLRDLFLALDSDGNGYLSYQELWNGLNGDDVRWDDASNADKRAVLDRLWLEADKDGSDQVTFAEFWQLIAASRSPTEDEMARAYDYFVRLDKSGDGYLDRLEIQEGLANPDIDWTLLGFDEGVKERHLFQARPISHRSPYDRHADSSGDGRVSFDEFWQMILTNISNRERARAAAAAQMVSVRDVAAWEPSDVGAWLDRVGYGAYRPAFEANGIHGYRLLALTFDALPRLSVRQFDHCRGIMNAIRTLRGIEPEILETTEDCYAKREFARAKPVGLARRLRFGDEGAFAREEKRLNDAYSRPAMIMTEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV51</accession>
    <name>C1MV51_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59055</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059314.1">
        <property type="nucleotide sequence ID" value="XM_003059268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV51"/>
    <dbReference type="STRING" id="564608.C1MV51"/>
    <dbReference type="GeneID" id="9684754"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59055"/>
    <dbReference type="eggNOG" id="ENOG502S3AJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PLSMEMK"/>
    <dbReference type="OrthoDB" id="2018659at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05483">
        <property type="entry name" value="retropepsin_like_bacteria"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034122">
        <property type="entry name" value="Retropepsin-like_bacterial"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="613"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="775" mass="82307" checksum="201210BBD8EF521D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVI3</accession>
    <name>C1MVI3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59388</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060042.1">
        <property type="nucleotide sequence ID" value="XM_003059996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVI3"/>
    <dbReference type="STRING" id="564608.C1MVI3"/>
    <dbReference type="GeneID" id="9685197"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59388"/>
    <dbReference type="eggNOG" id="ENOG502QQ6C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LEFAQSC"/>
    <dbReference type="OrthoDB" id="545302at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032076">
        <property type="entry name" value="TTC5_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038645">
        <property type="entry name" value="TTC5_OB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16669">
        <property type="entry name" value="TTC5_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="225"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 5 OB fold" evidence="2">
        <location>
            <begin position="311"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="432" mass="45778" checksum="F477DE78F1332045" modified="2009-05-26" version="1">MKAAADAKASLKVLLNDVVAVANDLEGPNHPATHRARALFTRGRLQEAAADPSTDEGAAMLTAAEEALKKAAKLDPALDGAWNCLGQLFWKKGNLEGAKNCYRAVLARGPNKKTHQAMSMLSRALAKSKAKPGSEEQKQLVAESMDHAKEAVKLDVADGASWYAVGMAYMAAFFADGASGAFYTLVPIRPHATKLAQSLKAYQNAEKGGPSGDGRAGGGGIGDSPDLHFNRAIVHRYVEEYGAALEGFRRAAALDPALPWRAEVDAVAAALTRLDDGCRGAGPMFKPKRLAPIVKALEGTGHAGNEIPREYAEASLKALREGAKENEGSATNVRVVVDATSSEAGGLNLHYVVVDREGTLCAMSVYGLEDGAVRHSSTLTLLSPCVRDVDATFEGRRFTFRLIRVDLPKQILVGGAMPVGRIARPRLASTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVY4</accession>
    <name>C1MVY4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_40627</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060119.1">
        <property type="nucleotide sequence ID" value="XM_003060073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVY4"/>
    <dbReference type="STRING" id="564608.C1MVY4"/>
    <dbReference type="GeneID" id="9685271"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40627"/>
    <dbReference type="eggNOG" id="KOG4199">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NECKTHE"/>
    <dbReference type="OrthoDB" id="449062at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22895">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22895:SF0">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ARM" evidence="2">
        <location>
            <begin position="331"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="570" mass="57216" checksum="38199E4561A57FED" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW12</accession>
    <name>C1MW12_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_18683</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059845.1">
        <property type="nucleotide sequence ID" value="XM_003059799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW12"/>
    <dbReference type="STRING" id="564608.C1MW12"/>
    <dbReference type="GeneID" id="9685572"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18683"/>
    <dbReference type="eggNOG" id="KOG3367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MQWRVAP"/>
    <dbReference type="OrthoDB" id="9449045at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032263">
        <property type="term" value="P:GMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006178">
        <property type="term" value="P:guanine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046100">
        <property type="term" value="P:hypoxanthine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050408">
        <property type="entry name" value="HGPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43340:SF1">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43340">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="190" mass="20457" checksum="7D0D5332DA91F99A" modified="2009-05-26" version="1">MSRSPPPIDVADHEVLYSADAIARRVSELAASIASDYAEKSPAFLITMTGAFVFASDLLRAMHPNTPRGATIDAIKAKSYVGTTSSERVTLSDGAASAVDVRGRHVVVIEDIVDTGVTLRELRAAMDARGAASVTCVALLNKRARRREELASDGPEYVGFECEDRFVVGYGLDLDGRCREWPYVGVLNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWD3</accession>
    <name>C1MWD3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LHCQ</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_70906</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060194.1">
        <property type="nucleotide sequence ID" value="XM_003060148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWD3"/>
    <dbReference type="STRING" id="564608.C1MWD3"/>
    <dbReference type="GeneID" id="9685345"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70906"/>
    <dbReference type="eggNOG" id="ENOG502QQ8A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FEVLHAR"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="47"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="391" mass="40881" checksum="37EAC21CBEF2C87A" modified="2009-05-26" version="1">MAARCLAARASPLPTRRRAAPSHRGGAPRIARPRRDAVVVVVRASDDDVDDDTSAEDLIVEVEDPQTSSSSSSSSSDVAPSSDADASSPLGDLISSPLFYVTFGILGGVGVVQKFENAALVLAAFPIVGLTLLSKSDFGRRLEENILERRPALEAKRSEVERLREEAMEASPLYGEARPLLPGISSPPPHLTGTLAGDRGFDPLRLGKTPESLARGVELELLHARWAMLAVVGVAVPEALSIAGALPEGAALAEPVWWKVGAAKLNGESLNYGGLGGFVIAGKQGVAVIAACQAVLMGGPEYARYVGIRSLEPVGVYLPGDANYPGGAPFDPFGLSDDADRFARQKVIEIEHGRLAMVAMLGCFAQAIVTGEGPVANWVSVFRRVGGGGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWE9</accession>
    <name>C1MWE9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_18503</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060203.1">
        <property type="nucleotide sequence ID" value="XM_003060157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWE9"/>
    <dbReference type="STRING" id="564608.C1MWE9"/>
    <dbReference type="GeneID" id="9685352"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18503"/>
    <dbReference type="eggNOG" id="KOG0230">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CSHRIAM"/>
    <dbReference type="OrthoDB" id="158357at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000285">
        <property type="term" value="F:1-phosphatidylinositol-3-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.810.10:FF:000001">
        <property type="entry name" value="1-phosphatidylinositol 3-phosphate 5-kinase FAB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748:SF7">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="2">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="231" mass="25568" checksum="AA66E0A2C11D2070" modified="2009-05-26" version="1" fragment="single">DDRFIVKEVSRAERNAFLDHGVGFAYFAYVESRLEDEDGVSGTCLAKILGMYQVATRSPMESTETKLDFLVMENVFYGRDVAAGATRADEVPPPWRTASATTPAVLLDENLMEVLATDPILVTERSKRALDAALRRDAAFLSSLGVMDYSLLAGVDRRADELVVGVVDYLRQYTWDKQLETYVKQSGLVGGGGPGKTPTVISPGQYEKRFATAMRRYFVCVPDDDDDREGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWF8</accession>
    <name>C1MWF8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_18278</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059916.1">
        <property type="nucleotide sequence ID" value="XM_003059870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWF8"/>
    <dbReference type="STRING" id="564608.C1MWF8"/>
    <dbReference type="GeneID" id="9685647"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18278"/>
    <dbReference type="eggNOG" id="ENOG502QS72">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CDPRIHF"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006869">
        <property type="entry name" value="DUF547"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46361">
        <property type="entry name" value="ELECTRON CARRIER/ PROTEIN DISULFIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46361:SF3">
        <property type="entry name" value="ELECTRON CARRIER_ PROTEIN DISULFIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04784">
        <property type="entry name" value="DUF547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="DUF547" evidence="2">
        <location>
            <begin position="3"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="222" mass="24861" checksum="114630F9A8F013D0" modified="2009-05-26" version="1">MTDEDEKLAFLVNVYNLMIVFAFARFGVPRSNAARYSFFDDVKVNIGGHAYSFNDIEQGLIRGNRRPPYHLRRTLRGGDVRRAFALARVDPRAHFALNCGASSCPPVKMYTPEGLDEELTLASKAFCEDSVTFDADANALTVSAILKWYRSDFGADDAAVARRVLTWLQGDTKTALENALRRENSSIKLRYAPYDWTVNATATSRSYEGVKTKVDVSRITGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWJ3</accession>
    <name>C1MWJ3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_18625</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059932.1">
        <property type="nucleotide sequence ID" value="XM_003059886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWJ3"/>
    <dbReference type="STRING" id="564608.C1MWJ3"/>
    <dbReference type="GeneID" id="9685666"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18625"/>
    <dbReference type="eggNOG" id="KOG4232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GMDTQLE"/>
    <dbReference type="OrthoDB" id="260091at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF19">
        <property type="entry name" value="DELTA(5) FATTY ACID DESATURASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="90"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="4">
        <location>
            <begin position="217"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="473" mass="53194" checksum="5D062B2978B57EFB" modified="2009-05-26" version="1">MSASALCAGAVRADAASSSSSSSSRRRVRASARAVSKTTTRVRASIAYPAPSGDAEPPKEKVVIKNNTNPLSAESAKPVNIKPKGEPVRIKIDDQWYDCAGWAKAHPGGERWIHFFDGRDGTDAFYALHSYGPNGSSKAADRLAKLPRCDPPPEKELKTPTPSEYAASMSFREFRKKLEADGFFKRDWLKETWALVQVLGLYAAGQFFAYSNPVMSTVLLGLGMVQAGWLGHDYVHGRGPLCEALRYMPTLLNGHGVEWWSQKHSMHHTFTNEEHMDNDVMMEPFFFLRPPSESGRPDSPLRKYQHIFGYPLLSIMFWLWRFHSAESAWRRKDKKELVLLGANYAWLAFCMPWQVAIGSVFLSGFIVASLVSATHQSEEIMEYGEGAEYVEGQFRSTRDAETVFGPLETWIWGGMDTQLEHHLFPTMPRYRYHALRPILKAWAKANDINYRISPSTKIIADNLKLLKEVAAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXC6</accession>
    <name>C1MXC6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60105</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060669.1">
        <property type="nucleotide sequence ID" value="XM_003060623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXC6"/>
    <dbReference type="GeneID" id="9685811"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60105"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015157">
        <property type="entry name" value="TMA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28632">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09072">
        <property type="entry name" value="TMA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="114" mass="12414" checksum="B10786AF3C01DF5D" modified="2009-05-26" version="1">MPGKEGGKAKPLKKAKGKQVELDDDDLAFKAKQKADAEKLKALKAQAAGKGFGGAIRADPRTRPPRLPFSISISRSRSRSHSHSRASARDRRRLTFGRPPLARRRAGGMKKSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXI8</accession>
    <name>C1MXI8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_60175</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase F subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060700.1">
        <property type="nucleotide sequence ID" value="XM_003060654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXI8"/>
    <dbReference type="STRING" id="564608.C1MXI8"/>
    <dbReference type="GeneID" id="9685842"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60175"/>
    <dbReference type="eggNOG" id="KOG3432">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IIICQHI"/>
    <dbReference type="OrthoDB" id="10261947at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10580">
        <property type="entry name" value="ATPase, V1 complex, subunit F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008218">
        <property type="entry name" value="ATPase_V1-cplx_f_g_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005772">
        <property type="entry name" value="ATPase_V1-cplx_fsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036906">
        <property type="entry name" value="ATPase_V1_fsu_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01101">
        <property type="entry name" value="V_ATP_synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13861:SF2">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13861">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01990">
        <property type="entry name" value="ATP-synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015945">
        <property type="entry name" value="ATPase_V1_F_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159468">
        <property type="entry name" value="AtpF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR015945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="129" mass="13784" checksum="9698A3C104184467" modified="2009-05-26" version="1">MTLEADGALVGVIGDEDTVTGFVLAGVGDVDERRRRNFLVVDDDTTEAAIREKFNELVARGDVAVVLVSQHVADRVRPLLDARAASGATVPAVLEIPSKDAPYDATRDAVLSRAQRALGRGDEDEELRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXW3</accession>
    <name>C1MXW3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH:ubiquinone reductase (non-electrogenic)</fullName>
            <ecNumber evidence="3">1.6.5.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_47955</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a ubiquinone + NADH + H(+) = a ubiquinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:23152"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.9" evidence="3"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060768.1">
        <property type="nucleotide sequence ID" value="XM_003060722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXW3"/>
    <dbReference type="STRING" id="564608.C1MXW3"/>
    <dbReference type="GeneID" id="9685899"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47955"/>
    <dbReference type="eggNOG" id="KOG2495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HVDVLTN"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) (non-electrogenic) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF47">
        <property type="entry name" value="EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910693" description="NADH:ubiquinone reductase (non-electrogenic)" evidence="13">
        <location>
            <begin position="23"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="404"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="450"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH55537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="594" mass="64826" checksum="AB1822ABD47A9D13" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYB8</accession>
    <name>C1MYB8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_68858</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060549.1">
        <property type="nucleotide sequence ID" value="XM_003060503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYB8"/>
    <dbReference type="GeneID" id="9685708"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68858"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="252" mass="27298" checksum="84F60EAF6FF6F985" modified="2009-05-26" version="1">MMISSRRCIREREKLGLEGRAAASERTAASASWTNADDVFSKSVRSLRGAGGPTTLVVAPRLEDALRAIERAIEKSTTSASSSHVANGDWCEIELEGLVANARDSLRRFERDARGLVTQRTFNPAFIVADIARGEWDVAVGVVRGFVARLHDAYVKAVDAVCSHEETTNAPAEAASIRDENVCSRFRDAKAAIADVSRRATRLRVRHGAEEAIDLAHGTLDVLCNARIDANDATGAAKYALLLLRDVLERGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYV5</accession>
    <name>C1MYV5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Starch synthase, chloroplastic/amyloplastic</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SSIIB</name>
        <name evidence="14" type="ORF">MICPUCDRAFT_44605</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Chloroplast</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Amyloplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061105.1">
        <property type="nucleotide sequence ID" value="XM_003061059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYV5"/>
    <dbReference type="STRING" id="564608.C1MYV5"/>
    <dbReference type="GeneID" id="9686289"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44605"/>
    <dbReference type="eggNOG" id="ENOG502QT35">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HEMECRN"/>
    <dbReference type="OrthoDB" id="512920at2759"/>
    <dbReference type="UniPathway" id="UPA00152"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009501">
        <property type="term" value="C:amyloplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010021">
        <property type="term" value="P:amylopectin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000048">
        <property type="entry name" value="Starch synthase, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45825">
        <property type="entry name" value="GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45825:SF2">
        <property type="entry name" value="STARCH SYNTHASE 2, CHLOROPLASTIC_AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0035">Amyloplast</keyword>
    <keyword evidence="4 11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0750">Starch biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Starch synthase catalytic" evidence="13">
        <location>
            <begin position="1"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="12">
        <location>
            <begin position="300"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH54755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="491" mass="54771" checksum="77FE9902231A1EB2" modified="2009-05-26" version="1">MVGAECAPFSKTGGLGDVMASLPKALVARGHRVMAVIPMYYHYDECGTPCGAVDLNICGEMQHVDYFHHNRDGVDLVFVSHPAFYENVSAIYGGGTMGVTWRGALLSQAAIEAVWHVPCGGFPFGTDNLIYVANDWHTAILPVYLRAFYQDHQILGYARSCLIVHNIAHQGRTHCDDVWRLNLPDHHTGAFYLDDPMEGPGMNVLKAGIEYATKVIAVSPGYAWEIGTDEGGWGLAPTIRNDPVKVSGIVNGIDFNEWSPEMDPYLQSDGYQTYGTNLEGWWTGKQACKAALQRQLGLEERHDVPLLGFIGRLDEQKGIDLILNSEEFLMSQDVQIVFLGSGRQDLQDRLHEMECRNRHAVRAWIGFSNEMAHRITAGCDILLMPSRFEPCGLNQLYAMHYGTVPVVHHVGGLRDTVRHFDGNHDAGGTGWAFERAEADKFQWSLGQAIYTLRNHKESFAAIGVRGMQQDLGWDHAAYLYEQKFIEAKYAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0E8</accession>
    <name>C1N0E8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_50992</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061380.1">
        <property type="nucleotide sequence ID" value="XM_003061334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0E8"/>
    <dbReference type="GeneID" id="9687064"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50992"/>
    <dbReference type="OMA" id="THDSMGQ"/>
    <dbReference type="OrthoDB" id="196293at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF23">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="22"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="525" mass="54459" checksum="FC2CD1E016F75026" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0I1</accession>
    <name>C1N0I1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase alpha subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_20702</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase alpha subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061644.1">
        <property type="nucleotide sequence ID" value="XM_003061598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0I1"/>
    <dbReference type="STRING" id="564608.C1N0I1"/>
    <dbReference type="GeneID" id="9686833"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20702"/>
    <dbReference type="eggNOG" id="KOG1625">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTFARIM"/>
    <dbReference type="OrthoDB" id="336885at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016722">
        <property type="entry name" value="DNA_pol_alpha_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054300">
        <property type="entry name" value="OB_DPOA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061">
        <property type="entry name" value="DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061:SF12">
        <property type="entry name" value="DNA POLYMERASE ALPHA SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22062">
        <property type="entry name" value="OB_DPOA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018300">
        <property type="entry name" value="DNA_pol_alph_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase alpha subunit B OB" evidence="7">
        <location>
            <begin position="24"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="6">
        <location>
            <begin position="125"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="417" mass="43466" checksum="72980B356DDFA60D" modified="2009-05-26" version="1">MIESRLRAFKRAVERRYPGLDCGGATYAASQDDVTVVGRVVCDSEGKLNEASVMLEGSVETSNGARVRLELRRLPRFSLFPGQIVCVQGSNPSGHCLVARRLIASVAPSGVKSTASSPAFGSLSVAIASGPYTCAGDLSYEPLNEFLAYCAETRPDAVVLMGPFVDAEHKSVRGDDAPLDVSFEDVFALRVRDALERFAADADDAGYAPSVVVMPSTRDVTHDAVFPQPPLLSERELELPRSCAIACAPNPGVFSINGVTFAACTQDVLRHLSAAEAAREPASGGAGGGAGGAAPDRMSRLAAHLPGQSSAYPLFPAPAGACLDASLAAHLEMDVTPDVLLVPSDLNPFAKIVAQPAGGDDEDAPAFVALNPGRLAKGNIGGTIAHVYVTEGAPEPGARGEQAHAIERRARVDIVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0L2</accession>
    <name>C1N0L2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_62870</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061661.1">
        <property type="nucleotide sequence ID" value="XM_003061615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0L2"/>
    <dbReference type="STRING" id="564608.C1N0L2"/>
    <dbReference type="GeneID" id="9687100"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62870"/>
    <dbReference type="eggNOG" id="KOG0543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KRPIDWA"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48313:SF1">
        <property type="entry name" value="OUTER ENVELOPE PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48313">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="188"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="233"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="434" mass="47246" checksum="4102CEE63D4E392C" modified="2009-05-26" version="1">MQRMAASMGGPGAMPPGAADQFKNMSADDLKRASEELKDMDPETLKSTMNAAQSQMQGQQDYVMRGAEQLKRDGNKLVGEEKFTDAIEKYMRVKNNLQDIQTPAARALRTSCMLNMSLCFNKTKRYNSAVSECTEVLLGDGRSLKAYYRRGQAHYAKGELARAVKDLRRAVKLAPGDETVAAECAKAESDMKEKGVVDEDDGACPAFEGPDPSSAPPATANPGGSGSFPGMPPGTSQAQMDQAMKMMKDPAAMSKAAEMMENMSEEQLEEMQKMAGAPKLDPGMAKQAAAMMKNMDPEAMSGMMEMAAKMREGGGMPGGGPSLGPDGQPTPEMMAAMTEQMKDPKMQEAMSSMMKNITPDQLKEMTKASGINMTDEQAEQTAKMMQSISPETMARMMKVGSFFQGTFARFRRTYQARSIHWSSYDRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1J8</accession>
    <name>C1N1J8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_41764</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061570.1">
        <property type="nucleotide sequence ID" value="XM_003061524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1J8"/>
    <dbReference type="STRING" id="564608.C1N1J8"/>
    <dbReference type="GeneID" id="9687274"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41764"/>
    <dbReference type="eggNOG" id="ENOG502S9G1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MHEIEHV"/>
    <dbReference type="OrthoDB" id="608866at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052450">
        <property type="entry name" value="TRBD-Containing_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734:SF1">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1 TERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="13"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="13"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="67"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="310"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="511"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="795"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="243"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="460"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="514"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="530"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="581"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="659"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="684"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="694"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="798"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="809"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="830"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="874" mass="91436" checksum="17F3A818435E6142" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1L8</accession>
    <name>C1N1L8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_51456</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S41B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061580.1">
        <property type="nucleotide sequence ID" value="XM_003061534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1L8"/>
    <dbReference type="GeneID" id="9687020"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51456"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012393">
        <property type="entry name" value="Tricorn_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43253">
        <property type="entry name" value="TRICORN PROTEASE HOMOLOG 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43253:SF1">
        <property type="entry name" value="TRICORN PROTEASE HOMOLOG 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="68"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="111" mass="11168" checksum="EBB1037D02FB0C51" modified="2009-05-26" version="1">MARPSAFTIPSFGPYDADGAWAIEQRGVVPDVVVANAPVATSRGGDAQLDAAIEVLNKKLAEAPAKGKVPIKPTYPNRSFDAKTCEAGGDGSAKEEGGGGEDAKAAKAVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1S6</accession>
    <name>C1N1S6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GOLD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_21205</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062171.1">
        <property type="nucleotide sequence ID" value="XM_003062125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1S6"/>
    <dbReference type="STRING" id="564608.C1N1S6"/>
    <dbReference type="GeneID" id="9687404"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21205"/>
    <dbReference type="eggNOG" id="KOG1692">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VGEYTFC"/>
    <dbReference type="OrthoDB" id="1929172at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912325" description="GOLD domain-containing protein" evidence="7">
        <location>
            <begin position="24"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="8">
        <location>
            <begin position="23"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="218" mass="24101" checksum="4B73C572A002A425" modified="2009-05-26" version="1">MTSRLFFFVVLLLALFFASPARAVKVAIAPDGRECVTVHATRVADTFSGFLTASSPDLDPRSYYGAFDLVVRDDEDNVAFQKNRVNDHKFEFESERAGAHEFCIHNRDHATRTVVYDVLVGHHFAHDAATRETVTDLEAAIISLKYITNEVRAEMEYQKERDRHHRANADSIAAKVTGYALLQAAALVGASAWNVAFVKGLFESKFGALGARHGGRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2D5</accession>
    <name>C1N2D5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51488</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062067.1">
        <property type="nucleotide sequence ID" value="XM_003062021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2D5"/>
    <dbReference type="GeneID" id="9687302"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51488"/>
    <dbReference type="OrthoDB" id="511048at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="149" mass="15558" checksum="09075C6A17C6EEFE" modified="2009-05-26" version="1">MATTTICSVSARVSAPSASSSSSSARRAFAPTPSSRSRGGCCVRRGRGSVVVLASARDEREKSKIGGRFGEKLGTPFADLKIGESVEKMATRYDWLSAGLGALLGCSYGVMRGQSVNQALGITMCATVVAVAIDELMRDQEKKNGDGTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2G9</accession>
    <name>C1N2G9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L7a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_51525</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062086.1">
        <property type="nucleotide sequence ID" value="XM_003062040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2G9"/>
    <dbReference type="STRING" id="564608.C1N2G9"/>
    <dbReference type="GeneID" id="9687311"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51525"/>
    <dbReference type="eggNOG" id="KOG3166">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RMVKWPA"/>
    <dbReference type="OrthoDB" id="29563at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001921">
        <property type="entry name" value="Ribosomal_eL8_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00882">
        <property type="entry name" value="RIBOSOMALL7A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="6">
        <location>
            <begin position="125"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="263" mass="29328" checksum="F2190FF1B83CA63F" modified="2009-05-26" version="1">MPPKGKKPAPAPAGVKPAAAAKSPSDPLFEKKAKTFGIGQSLPPRQPLNRYVKWPKYVRIQRARRVLQKRLKVPPAINQFNNTLDKNLATSLFKILMKYRPEDDAQKKERLTAQAAAEAAGKEVESKKPVVVKYGINHITYLVEQGKAQLVCIAHDVDPIELVIWLPALCRQMNVPYCIVKGKARLGTVVHKKTATALALTAIKNEDKMEFSKLVEAIKGSYNDRFEASNRKWGGGIMGVKSQAKTKKKQRIIDAELRAREKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3H8</accession>
    <name>C1N3H8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42197</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062614.1">
        <property type="nucleotide sequence ID" value="XM_003062568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3H8"/>
    <dbReference type="GeneID" id="9687820"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42197"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="701"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="759" mass="75640" checksum="4F6F0B49FE74817A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3K3</accession>
    <name>C1N3K3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_5588</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062390.1">
        <property type="nucleotide sequence ID" value="XM_003062344.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3K3"/>
    <dbReference type="GeneID" id="9687830"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5588"/>
    <dbReference type="eggNOG" id="KOG2361">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KLHANDF"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF14">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="279" mass="29952" checksum="0184CB846186B32C" modified="2009-05-26" version="1" fragment="single">WDAFHSAHDAGAFFKERRYLLEAFSTPLRRGGSVVACEVGCGSGSAALPLLRGCEDAFVFACDFSAAAVRCAERAVKAADDADADGGRAARIGNRFRAFRCDPSSASLLDAVQKALVAGGPVAEPCPPALSLHAWKMGLPILDVVLLVFVLRRVPAVPPGDASATFLKSVFAALAPGGVVCFRDYGIYDHAMLRFSPSQRTEERTYVRGDGTLARFFTVEEARDAFGAAGFVEVGGGEGAEAADQDPLRYCCVHNENKRKGIKMRRVFVHGTWMRPMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3L5</accession>
    <name>C1N3L5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_52219</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat WDR55 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062395.1">
        <property type="nucleotide sequence ID" value="XM_003062349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3L5"/>
    <dbReference type="STRING" id="564608.C1N3L5"/>
    <dbReference type="GeneID" id="9687835"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52219"/>
    <dbReference type="eggNOG" id="KOG2444">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QAIHPTE"/>
    <dbReference type="OrthoDB" id="2288928at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF20">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="58"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="101"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="332"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="361"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="399" mass="42638" checksum="0C2D5A1343B9BD55" modified="2009-05-26" version="1">MDSEGGESCSAICAEQPFDVRFHPTKNGALFCASLVTGEVEVWEHSIEDEACTLLKTLKCHDDACRSIAFANDGALLLSGGSDRSILASDVATGAAVARLENAHKAAINKLVALDANILATGDDDGVVKVWDTRTRRACGSFAPFVDFVSDIYHVPASAAADVDDAVANAASAAAGNPAGTLVVASGDGTIAHLNLATWKELGQSDNLEDELLSCCVMKHGKKAVAGSQGGILNIFDYGEWEDISDRFPGHPSSIDAIVKVDEDTILTGSADGLIRVINIHPNKMLGLVGEHGEMPVERMDLSVGNQWLATASHDRSVKLWSVGYLWEEDDDEDDLKEKVGEEEEEEEEDSDDSDDDGGGGKRKRKQGKKKKGKNKVKDAHAARADAKKRTAKKFFEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3U9</accession>
    <name>C1N3U9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_4590</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062679.1">
        <property type="nucleotide sequence ID" value="XM_003062633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3U9"/>
    <dbReference type="STRING" id="564608.C1N3U9"/>
    <dbReference type="GeneID" id="9688119"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4590"/>
    <dbReference type="eggNOG" id="KOG2106">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47802at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF33">
        <property type="entry name" value="HELP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EML-like second beta-propeller" evidence="4">
        <location>
            <begin position="3"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="121"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="269" mass="28987" checksum="C691EDDBBB61E0BA" modified="2009-05-26" version="1" fragment="single">HGTPNVFITAAGSGDVFWWDAANTVVARGTNVGFTARTVAADGTLPDRSHHVAIGGGGGELCVLDERDLRVVFHDCARKAGVEDVKYSPDDTKLAVSSRDAMIDVYAVRGKNETYQRVFRLRGHSAAVRHVDWSVDSRALGSDGADYELLHWDASTGKQLTSATNDVRWHTWTRVLGFPVMGLWPPGSDGTDVNAASRDPKGELLATADDAGVVKLFAYPCVVEDAPHRRSVGHASHVMGVAFSPCGNRLLSVGGTDRCVFQYDVVRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3Z6</accession>
    <name>C1N3Z6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52354</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062703.1">
        <property type="nucleotide sequence ID" value="XM_003062657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3Z6"/>
    <dbReference type="STRING" id="564608.C1N3Z6"/>
    <dbReference type="GeneID" id="9687899"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52354"/>
    <dbReference type="OMA" id="NPIRWSL"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="217" mass="22762" checksum="1B799A80B2FA6C1A" modified="2009-05-26" version="1">MSTAVFAATPTPARFASSSHVTRPRPRMGKGGIQPRSPGKRVGATSDDNNSNDANNDIPAPSPSTNVDDIAAALGGAAPARERAIAGIWIGESWPAPELLAIDPSVPTNPIRWSLALDPAASAPTPSAFGAGTFDDSGDIPGEPVIWFTLRGTFDALTRAVKLRKVYERPVPESEVKYEGRLHALNGAPEITGVWRNSTSGTNGTFSCTLQESGRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1N471</accession>
    <name>C1N471_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_29323</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062498.1">
        <property type="nucleotide sequence ID" value="XM_003062452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N471"/>
    <dbReference type="STRING" id="564608.C1N471"/>
    <dbReference type="GeneID" id="9688179"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29323"/>
    <dbReference type="eggNOG" id="KOG0570">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HTIFINM"/>
    <dbReference type="OrthoDB" id="10253553at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009244">
        <property type="entry name" value="Mediatior_Med7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044888">
        <property type="entry name" value="Mediatior_Med7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428:SF11">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05983">
        <property type="entry name" value="Med7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="194" mass="21449" checksum="948279FD3A9C0B63" modified="2009-05-26" version="1">MSSTYPPPPGFYKLYAPDATTPPPPPPAPVVGEYVVYGERHSTVISDPPFEQSKLYLSEGEGVDLREELKRLNAETLARFVALVDATRAAPSTYARRVEEITLLLNNMHHLLNSIRPSQARSTLEHVLSEQVREKRAALAKLRADAAAAEATMGNPPNDALRATVRRAIDGATREETEDKEEEEEREKAMDVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4C8</accession>
    <name>C1N4C8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_6517</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062978.1">
        <property type="nucleotide sequence ID" value="XM_003062932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4C8"/>
    <dbReference type="STRING" id="564608.C1N4C8"/>
    <dbReference type="GeneID" id="9688206"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6517"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AWCHENG"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="191" mass="21204" checksum="A80D98356F514D09" modified="2009-05-26" version="1" fragment="single">GDAVAMYWIGVCYSCGFGVKEDKTKAVEWWERASGCGFAYATYRLAWCHENGCGVEKNETKAIELYLKSVEATGDADAMCWIGYCYHYGYGVKEDYTKAVEWWERASGCGHASATTYLAMCYDTGHGVEESETKTRELYLKAAELGCKDAAYELGIIYYHGACGVAVNKTEALKWWRVAVELGDTFVQGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4L3</accession>
    <name>C1N4L3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_52601</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062811.1">
        <property type="nucleotide sequence ID" value="XM_003062765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4L3"/>
    <dbReference type="STRING" id="564608.C1N4L3"/>
    <dbReference type="GeneID" id="9688251"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52601"/>
    <dbReference type="OMA" id="GEAHQWF"/>
    <dbReference type="OrthoDB" id="531840at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="84"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="438"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="558" mass="58615" checksum="6B7C69BB5515BEF9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4W5</accession>
    <name>C1N4W5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52703</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062864.1">
        <property type="nucleotide sequence ID" value="XM_003062818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4W5"/>
    <dbReference type="STRING" id="564608.C1N4W5"/>
    <dbReference type="GeneID" id="9688304"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52703"/>
    <dbReference type="eggNOG" id="KOG0087">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YHEAHAC"/>
    <dbReference type="OrthoDB" id="48625at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001656">
        <property type="entry name" value="Rab11B GTPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="230" mass="26026" checksum="6350C585202945AE" modified="2009-05-26" version="1">MADDGHFPRVTTDDTAAATDTEAFLKALKVQEGKTGEEGKDELSLVTSKGAIKIILLGDSAVGKSKLVERFLMDGYQPQQLSTFALTLFRYNFNHPDGRVVAVDFWDTAGQERFNNLHPSYFYRAHACILAFDVTRKVTYKNLDRWYRELEEYCPGIPTIVVANKIDVDYRVTERTFAFPERRNLPFAFVSASDGTNVVKTFQQAIMMGIKQKENPSDDFLTMALELLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N551</accession>
    <name>C1N551_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66926</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063105.1">
        <property type="nucleotide sequence ID" value="XM_003063059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N551"/>
    <dbReference type="GeneID" id="9688545"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66926"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="133" mass="14609" checksum="2E81CFB5788974DD" modified="2009-05-26" version="1">MREIRPVDAELLTTCFDAADAASAPEDTRAFYEWFYSALDDAERGSFMERLMRQKEKLAERCLARVSARYLHRDMRIVKSDGEGFDGDGDGDGDGDGDGDGDGDGDGDGDGDEQIMTYFLRGVAAGMQLARSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5Y0</accession>
    <name>C1N5Y0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42732</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063442.1">
        <property type="nucleotide sequence ID" value="XM_003063396.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9688676"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42732"/>
    <dbReference type="OMA" id="GASRCAC"/>
    <dbReference type="OrthoDB" id="10693223at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711:SF1">
        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="752"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1248"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1443"/>
            <end position="1471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1671"/>
            <end position="1690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2047"/>
            <end position="2074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2366"/>
            <end position="2403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1454"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2047"/>
            <end position="2057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="2367"/>
            <end position="2394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2403" mass="243781" checksum="702A063D4707C564" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5Z6</accession>
    <name>C1N5Z6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_53104</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ELP6 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063245.1">
        <property type="nucleotide sequence ID" value="XM_003063199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5Z6"/>
    <dbReference type="STRING" id="564608.C1N5Z6"/>
    <dbReference type="GeneID" id="9688888"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53104"/>
    <dbReference type="OMA" id="HRDACAW"/>
    <dbReference type="OrthoDB" id="10650788at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018627">
        <property type="entry name" value="ELP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184:SF6">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="328" mass="33581" checksum="3BF7EB9FD4016072" modified="2009-05-26" version="1">MNVDAALGVRGDVLPRGALVLVTDTVETSAEFVVSHFLRRALAASDAARAAADAADGGGGGGEWKTCLVTSERCVAHHANAMRKWGRNLRADVKDGKLVVVDAHDSTPGWATTRARGGDGDGDGDAVIDESSPAKDVYEQIARALGLNDGAGDEDGGASSSSSSSSAAAASRVVVFDGVDAIAEAEESLERRRGRRGDRTRAPVTSRGRVHAMVRSLLAHDSGVAVVALAHADAAGGEAIESGGWLRRLTSDADVVARVEALPSGVASDVHGLITATHRTGRMLPPPGDGDGDAARAGEASARFRLTELGAELTRVIRSRAVAADATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N600</accession>
    <name>C1N600_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48831</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063451.1">
        <property type="nucleotide sequence ID" value="XM_003063405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N600"/>
    <dbReference type="GeneID" id="9688687"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48831"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="478" mass="52040" checksum="A79F79EAFB9A8413" modified="2009-05-26" version="1">MDADERLARGDALVKSLEKAGCAHAVCLKATRDAGVGVFAARDVEGGGVLVRCPVAHAWYARDGDEFDDAIDALRVDGEPLDARERLQLHLLNERARSDVDKAPASDENLVQISRARYVLSLPGAELVNALPIGWSDEDIERRLRGDLLSRTRATLARIHAVADAIARSRSKAFGDADDAFFVFSVDDLKWAHAVFWSRAMTLRFPRKGFTGGGDVDALVPLVDMCNHRAGSTATLEIVEDDAGDAFYELRAGVATKAGDEVFINYGAKGNEELLRCHGFVIPNNPCDVLAVDLRKLWLWKGDVHWRGDVAASEAEAEAALRERDLPTRAFLHRAVDGDAFALPDAMISAARSRYEMEDPRPGREKDAEKRLERRASAAIIRLVGEIFSLVGRGDETVDVEALCKKDCSGIEATGENADVACAIVRKSAVEISNAALRAALVWPSALEPGGDQAEDASENGPEKDKKRAREDDAWESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6L6</accession>
    <name>C1N6L6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53356</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063571.1">
        <property type="nucleotide sequence ID" value="XM_003063525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6L6"/>
    <dbReference type="GeneID" id="9689198"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53356"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="148" mass="15676" checksum="337D61D8194CACF5" modified="2009-05-26" version="1">MNPRSARSNAAGNDATRASASRKTRPTRASAQRSRAFGRNEKTRHARAGSAARTSPRVAAAGAALGSGGEAFGRRDLVITTRGVEGARVEECAARAPLLARHGKSNSRSQPAGAKTEHSAPVRAAPGEASLRPRAAHHSRWRRRRTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7K5</accession>
    <name>C1N7K5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="4 13">1.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">P5CR</name>
        <name evidence="17" type="ORF">MICPUCDRAFT_53732</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-proline + NAD(+) = (S)-1-pyrroline-5-carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>L-proline + NADP(+) = (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="4 13"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063918.1">
        <property type="nucleotide sequence ID" value="XM_003063872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7K5"/>
    <dbReference type="STRING" id="564608.C1N7K5"/>
    <dbReference type="GeneID" id="9689556"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53732"/>
    <dbReference type="eggNOG" id="KOG3124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PHIENLQ"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000190">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13" id="KW-0521">NADP</keyword>
    <keyword evidence="10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 13" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="15">
        <location>
            <begin position="68"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="16">
        <location>
            <begin position="264"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="353"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH51540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="375" mass="37985" checksum="189187A08236952E" modified="2009-05-26" version="1">MLRAATVRVSRGGSAALERQLASRHLGGGRRAASRVFPGVAGRCRHREIAVVARASSSTPPPPLALGTVGFIGAGSMAEAMARGFAESGAVSPSSMRVSRSSDAARAARWTNLGVEALASNGDVARVSDVVVLAVKPHVLPGVLTEIASHVSPETLLLSVAAGVSTSFIERAVSDARGGGGSRDDDRRFSPPRVIRVMPNTPCQVRAAASSVSAGAHSSSADLDAIASLMRAVGACVVVDESLIDAVVGVRRVPSYTGPHTTPGSGPAYVYQIIEAMADGGVLCGLPRADATLLAAQTVMGAAKMVLESGEHPAALKDKVCSPGGTTIRAVAAMEAAGVRAGMIAAVRASAERSAELGRATDEAEAKATGTGKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7K8</accession>
    <name>C1N7K8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription initiation factor IID, 31kD subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_70865</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF9 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063920.1">
        <property type="nucleotide sequence ID" value="XM_003063874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7K8"/>
    <dbReference type="STRING" id="564608.C1N7K8"/>
    <dbReference type="GeneID" id="9689359"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70865"/>
    <dbReference type="eggNOG" id="KOG3334">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YEPRVVT"/>
    <dbReference type="OrthoDB" id="341924at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07979">
        <property type="entry name" value="HFD_TAF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003162">
        <property type="entry name" value="TFIID-31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051431">
        <property type="entry name" value="TFIID_subunit_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068">
        <property type="entry name" value="TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068:SF4">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02291">
        <property type="entry name" value="TFIID-31kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="180" mass="19518" checksum="1BBBA9DFF27AD6F3" modified="2009-05-26" version="1">MPVSKTVIAAAAAAAASTNAEVRAAEGKMPRDAAVVINVLRSMGVTEWEPRVVNMLMEFIHRYTSQVLSDSVAYTKHRGGAEVNVDDVKLAIETKLMREFHAPASVEDMRDRAAALNAIPLPELSNRPGIHVPQDDNLLGAHVQYFPRPGGVLIGEEGRRGAFSLHWSPYDRVGVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7L9</accession>
    <name>C1N7L9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_53750</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063927.1">
        <property type="nucleotide sequence ID" value="XM_003063881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7L9"/>
    <dbReference type="STRING" id="564608.C1N7L9"/>
    <dbReference type="GeneID" id="9689561"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53750"/>
    <dbReference type="eggNOG" id="KOG2209">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1914979at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF205">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="119"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="339"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="565"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="614"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="687"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1207"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="354"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="572"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="627"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="723"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1245"/>
            <end position="1256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1256" mass="132606" checksum="540A95F4DCCA734B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N848</accession>
    <name>C1N848_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">40S ribosomal protein S2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_49763</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064019.1">
        <property type="nucleotide sequence ID" value="XM_003063973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N848"/>
    <dbReference type="STRING" id="564608.C1N848"/>
    <dbReference type="GeneID" id="9689460"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49763"/>
    <dbReference type="eggNOG" id="KOG0877">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PYEEWSD"/>
    <dbReference type="OrthoDB" id="10253125at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000067">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000004">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_uS5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_uS5_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718:SF4">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="RIBOSOMAL S SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="9">
        <location>
            <begin position="72"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH51641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="259" mass="28308" checksum="587561D77A663D04" modified="2009-05-26" version="1">MADRGGDRGGDRGGFGRGFGRRGDDKEAGWTPCTKLGRLVQQGKIKSLEHIYLFSIPVKEYQIVEHFIGAQLTDEVMKIMPVQKQTSAGQRMRFKAFVVVGDSNGHIGLGVKACKEVAHSIQGSMILAKLNIVPVRRGYWGGKLGAPHTIPAKSTGKCGSVTVRLVPAPRGAGIVAAITSKKVLAMAGVQDVYTQTTGSTKTLGNFVKATYYALKKTYGFLSPELWRETTFTKPPAQEFTDFLSMKKEISHKTHDDDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N850</accession>
    <name>C1N850_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43247</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064020.1">
        <property type="nucleotide sequence ID" value="XM_003063974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N850"/>
    <dbReference type="STRING" id="564608.C1N850"/>
    <dbReference type="GeneID" id="9689649"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43247"/>
    <dbReference type="OrthoDB" id="20573at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1440">
        <property type="entry name" value="PHAX RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019385">
        <property type="entry name" value="PHAX_RNA-binding_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038092">
        <property type="entry name" value="PHAX_RNA-binding_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10258">
        <property type="entry name" value="PHAX_RNA-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphorylated adapter RNA export protein RNA-binding" evidence="2">
        <location>
            <begin position="97"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="220" mass="23332" checksum="F4DF93EDBA1BF7A7" modified="2009-05-26" version="1">MDADVAADDDSEEEEGEVPALDARRARGAEDGARAVGDDGSKKRGRDDAPADADAAPAPAPAADDGGFGFGIDMSDLLKTFPGHAFVPLDERELVCAEKIAKCVDEKKKHLIRLLVKRFGVPLAEDALRETMKVERAGGSWLEERGRPPRRRSAGGVFISLVRKRAEARDGGGRAFKAVMKQSAGIDKLLREQKERDERAGGEKRARTSGGGAGVGAGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8H5</accession>
    <name>C1N8H5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54087</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064268.1">
        <property type="nucleotide sequence ID" value="XM_003064222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8H5"/>
    <dbReference type="GeneID" id="9689526"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54087"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10175">
        <property type="entry name" value="MPP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="161" mass="16691" checksum="E5083053F2E1FD1A" modified="2009-05-26" version="1">MQRAQEKEKLAAATAAAETHLAATAAVATTKAAPKVNPEEIWFTPGMERKDDGDASAAAPPPPPPPCRMSFGGFNPATEKLMREREEDARRRAAAASAARAKDADVSDADMASRLGGGGGARANANAKKKAPAAAAASEPEVRSISHWSPYDRVGDVDADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8K9</accession>
    <name>C1N8K9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_30266</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064284.1">
        <property type="nucleotide sequence ID" value="XM_003064238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8K9"/>
    <dbReference type="STRING" id="564608.C1N8K9"/>
    <dbReference type="GeneID" id="9689544"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30266"/>
    <dbReference type="eggNOG" id="KOG0879">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CVSIYGH"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000021">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="21"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="185" mass="20260" checksum="115DB5D98E8B300C" modified="2009-05-26" version="1">MPAEETQWHARPPNPSNPVVFFDVTIGGADAGRIKMELFADVCPKTAENFRQLCTGEFRKNGFPQGYKDVEFHRVIKDFMIQGGDYLKGDGTGCACIYGSKFADENFLGKHTGPGLLSMANSGPNSNGCQFFLTCTKTEWLDDKHVVFGRVLGDGLLVLRKIENVGTGANNKPKLSCKISQCGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8P1</accession>
    <name>C1N8P1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54186</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064480.1">
        <property type="nucleotide sequence ID" value="XM_003064434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8P1"/>
    <dbReference type="GeneID" id="9689921"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54186"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="230" mass="25625" checksum="D50EDC1DD8569DF2" modified="2009-05-26" version="1">MKRAKERAVSKITAVDAKVKRNDVAMENDAMRIYDDSFSMRARAEDTLLNRGTIEPMVSDTKRALRETEDECKHAVRRLNAALVNLGTAIAPALDVKEHIDAATKEDLLHLTDAVEVIEWKAADRAVMAWERFVDAASRVEDLLRPRARARVVLEEKIKRLEEGRFVTIEEDEEMRDRGRKDVVNRVRLKLRGGGDGGGGDSPSSVDGDGDVLDEEDVPSPPTSNPPLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9F6</accession>
    <name>C1N9F6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_54488</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064442.1">
        <property type="nucleotide sequence ID" value="XM_003064396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9F6"/>
    <dbReference type="STRING" id="564608.C1N9F6"/>
    <dbReference type="GeneID" id="9690054"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54488"/>
    <dbReference type="eggNOG" id="ENOG502QTIB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11715">
        <property type="entry name" value="THUMP_AdoMetMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054170">
        <property type="entry name" value="RlmL_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47313">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47313:SF1">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22020">
        <property type="entry name" value="RlmL_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="7">
        <location>
            <begin position="220"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="48"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="78"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="438" mass="47005" checksum="B4D90DEB0C618F8D" modified="2009-05-26" version="1">MLLTRCFGALPWAARASLATTTTRVRALHVAPRPRALDGWRVVHHGRRVATSAGGTRGGGGNGGADDGRWTMGAGGGVDREGYDRDDRDDRDDRDARRARGDDRGGRGGRRGRGGRGGGAASAARGGESSASSAARYRGGSDAPEWTRARRDSRRNAEGAPLSRSRYPPRSRDDERWERPSSRGGPRSDFDDFDESSFRLDHRGGGERRPERFRDAVRDDSGVNDWTCAACGENNFARRVACFRCGAGKEEGAGVGDDARTPRTASGAFYTLVPIRRRSRGERRSLRTFPGVFYATCHPGLEEVVAAELSSPLIGAIDVAPGASGVSFAGDARVGYLANVWLRSAIRVLVEMRRGWLDPSAPGGAAVYDFVKGAAPWEDVVPGGVGARDPLTFSVESRVWSCSDVTSTRLASTRAKDAVCDALVDATGYVVKDRLMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9N8</accession>
    <name>C1N9N8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_54559</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH50980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064646.1">
        <property type="nucleotide sequence ID" value="XM_003064600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9N8"/>
    <dbReference type="GeneID" id="9690209"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54559"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22710">
        <property type="entry name" value="X-RAY RADIATION RESISTANCE ASSOCIATED PROTEIN 1 XRRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22710:SF2">
        <property type="entry name" value="X-RAY RADIATION RESISTANCE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="148"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="502"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH50980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="655" mass="69667" checksum="32935DD5ADA533A1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Q7</accession>
    <name>C1N9Q7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_54586</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064777.1">
        <property type="nucleotide sequence ID" value="XM_003064731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Q7"/>
    <dbReference type="STRING" id="564608.C1N9Q7"/>
    <dbReference type="GeneID" id="9690218"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54586"/>
    <dbReference type="eggNOG" id="KOG1169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="242257at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007200">
        <property type="term" value="P:phospholipase C-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037607">
        <property type="entry name" value="DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000756">
        <property type="entry name" value="Diacylglycerol_kin_accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255">
        <property type="entry name" value="DIACYLGLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255:SF54">
        <property type="entry name" value="DIACYLGLYCEROL KINASE THETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00609">
        <property type="entry name" value="DAGK_acc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00045">
        <property type="entry name" value="DAGKa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Diacylglycerol kinase accessory" evidence="7">
        <location>
            <begin position="91"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="261"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="406" mass="43633" checksum="8E7CBC14C24BE98E" modified="2009-05-26" version="1">MRDATPSRLDRWGVTIDTIAKGPFCELEKGNPAGPLFGSRDAGAVFGFTPEESEFSPLVAHKAACASREASYEPSVNANGDADGKPSGEVIFHNYLGIGVDAAAALRFSRLRDHSPFLFVSALTNKLLYGVLGAEDVLTRSCGDLHRKDFLLTPAYTCFSPPTPPLASLSIPTRPPSTPFNSASDAFQLSPQVTLVADGEEIALPRDAEGVILLNINSYAGGVKMWERGPRFRLGEGASEGGWWEEWWRGLRGDGGGMVMGPDADGGEKDASAGGDVLPTTNNISPRQKKQQQQRHHGEFGDSAADDGRLDVVVVRGALHLGQLNLGVSTPARLCQAKRVTLKVDRPMPMHVDGQPWEQEGPCEITVGLKASGGLDRHPYEYVGRSRVVLVPLRRSASRRVDAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9R9</accession>
    <name>C1N9R9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_43608</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064784.1">
        <property type="nucleotide sequence ID" value="XM_003064738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9R9"/>
    <dbReference type="STRING" id="564608.C1N9R9"/>
    <dbReference type="GeneID" id="9690225"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43608"/>
    <dbReference type="eggNOG" id="KOG2172">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EHALSGW"/>
    <dbReference type="OrthoDB" id="277439at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006709">
        <property type="entry name" value="SSU_processome_Utp14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150:SF12">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04615">
        <property type="entry name" value="Utp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="100"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="587"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="694"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="854"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="934"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1056"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="196"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="271"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="597"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="616"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="695"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="765"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="805"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="871"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="889"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="902"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1077" mass="115246" checksum="9409B19050919530" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAC9</accession>
    <name>C1NAC9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_54848</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064883.1">
        <property type="nucleotide sequence ID" value="XM_003064837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAC9"/>
    <dbReference type="GeneID" id="9690315"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54848"/>
    <dbReference type="OrthoDB" id="527024at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="35"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH50863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="89" mass="9648" checksum="4A9CF5E503703D72" modified="2009-05-26" version="1">MCQFDTVVHGRSERPRGGGQGADRGRCGRERSENGGWTPLHEASREGHEAVVKALIKALVEAGEDINKTDFDGETSLSWAADQGHEVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAF5</accession>
    <name>C1NAF5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54883</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064953.1">
        <property type="nucleotide sequence ID" value="XM_003064907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAF5"/>
    <dbReference type="GeneID" id="9690338"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54883"/>
    <dbReference type="eggNOG" id="ENOG502T1XU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5373426at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH50933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="354" mass="40286" checksum="0235514F1B423D9D" modified="2009-05-26" version="1">MRTISLEKVLQTSSCSVFRSAVFVVCVFLLFSGRAKRNFQNSAQASGQGGVEPLYADWTPDHSCRHEPHSFTCTPSGKSWPHRTPLNPCQGLVDKKVLFVGDSFAQYAHNAFIVWLSGNYKDGAMQASHDEECIGEYQFGENVSCRYQEISATGKEHFFCNGRTAVKFVGYAHGGNYPGFFNQTLRDYDLIVYSIGRHPYDGNYDERSGVNDAESLYHNAFLNSCKDTNATEMCEKVVWLDTHVRISALYTDEKYDKQIRFHIESPTWVFRGCGIRRVASVWDATELLVTQHPVDAHEMSWDKVHYGLAINLLKAHEIFNEWAKKVQCADANQSFVYNHAKHIEVEQGRLESYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGP6</accession>
    <name>C1MGP6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61108</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055355.1">
        <property type="nucleotide sequence ID" value="XM_003055309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGP6"/>
    <dbReference type="GeneID" id="9681021"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61108"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="318" mass="33635" checksum="57F433C3330A767B" modified="2009-05-26" version="1">MSPLGGRLALAATAKHPGIKRTRALTLQSPSAATHVPKCGRGCDVLDDVVADDVEKRDDPSRSTTTTTTAARHARRRSLDANFTMDGVASLAATTAAAAADVLSPKRAAHARCASGPLSARGLGSAEDALLRGRDGIAYIDGTKMPRDGWYQRCFGCGSWTAQSVVLGDFEVFRCAACAKEFRRRSRASAAADDADDGVAARRRSSDATSTTSTTSSDAEDDETTASSSSPNLIPNNPDPRARTARKIAIRRRRRRSVGEAAAAELPAVDARTLTTLVSKLRRFLIEARPKNGVECSMTRRTHASGMLPTSPRPAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHM1</accession>
    <name>C1MHM1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 3 subunit A</fullName>
            <shortName evidence="6">eIF3a</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Eukaryotic translation initiation factor 3 subunit 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_46246</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eIF-3 subunit A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055515.1">
        <property type="nucleotide sequence ID" value="XM_003055469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHM1"/>
    <dbReference type="STRING" id="564608.C1MHM1"/>
    <dbReference type="GeneID" id="9680459"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46246"/>
    <dbReference type="eggNOG" id="KOG2072">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EHITNKR"/>
    <dbReference type="OrthoDB" id="18884at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071540">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3e"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002188">
        <property type="term" value="P:translation reinitiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.10:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.860">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.10">
        <property type="entry name" value="UVR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03000">
        <property type="entry name" value="eIF3a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027512">
        <property type="entry name" value="EIF3A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054711">
        <property type="entry name" value="eIF3a_PCI_TPR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14005:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14005">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22591">
        <property type="entry name" value="eIF3a_PCI_TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="322"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="731"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="815"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="579"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="677"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="817"/>
            <end position="954"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="963" mass="111992" checksum="0B770C328445C569" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHR3</accession>
    <name>C1MHR3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N-alpha-acetyltransferase 40</fullName>
            <ecNumber evidence="4">2.3.1.257</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_37945</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-seryl-[histone H2A] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H2A] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12742"/>
            <dbReference type="Rhea" id="RHEA-COMP:12744"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64738"/>
            <dbReference type="ChEBI" id="CHEBI:83690"/>
            <dbReference type="EC" id="2.3.1.257"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N-terminal L-seryl-[histone H4] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H4] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50596"/>
            <dbReference type="Rhea" id="RHEA-COMP:12740"/>
            <dbReference type="Rhea" id="RHEA-COMP:12743"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64738"/>
            <dbReference type="ChEBI" id="CHEBI:83690"/>
            <dbReference type="EC" id="2.3.1.257"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. NAA40 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.257" evidence="4"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054998.1">
        <property type="nucleotide sequence ID" value="XM_003054952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHR3"/>
    <dbReference type="GeneID" id="9680283"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37945"/>
    <dbReference type="eggNOG" id="KOG2488">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PVAFAHF"/>
    <dbReference type="OrthoDB" id="424551at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043998">
        <property type="term" value="F:histone H2A acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010485">
        <property type="term" value="F:histone H4 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039949">
        <property type="entry name" value="NAA40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20531">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20531:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="13">
        <location>
            <begin position="151"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="269"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="354"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="361"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH60250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="443" mass="46829" checksum="05252129F68612A1" modified="2009-05-26" version="1">MSKCGSGGSSKGGGSKSKSKGGRGDALHKKVALQTNDVKEHLSILRSALRDELGNDRDVLAGFGPFTKFDRNGLELDVSFRTGTSISDDELEWAHALVTSNLAARGQEMDAQALMDDLCDPSSRYYLVTERAVASEKTTKTGKKKKSAAAGKPVAFAHFRFTVQGEVRDAMAGEPVLLLRDLHVVEACRRRGVGKHLCSVLELTARKNAMRGVMILAPVGEAGVAARAFIDAKLRGFERADAEWTPSARNLSAFAKSLVAAKPAAVAAKADAPTTAGSPDSILKGPDATEATKENAAPEAAAKLETAFEKTTLEEPAPPPAPAPAPAPAPALFGDFAAAPVADVVAAKPSLSFADFGTSAPEEDASEDEDDDDEEDDDEDGDGDWQEVDAEDGDEKDDDEADDILSQLVELFKTENGRDPTEEEMAQWVETLKAASEEGGLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHS8</accession>
    <name>C1MHS8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_50307</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055007.1">
        <property type="nucleotide sequence ID" value="XM_003054961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHS8"/>
    <dbReference type="STRING" id="564608.C1MHS8"/>
    <dbReference type="GeneID" id="9680211"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50307"/>
    <dbReference type="eggNOG" id="KOG0294">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WDIKSAH"/>
    <dbReference type="OrthoDB" id="308449at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051959">
        <property type="entry name" value="PAK1-Kinase_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675:SF1">
        <property type="entry name" value="P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675">
        <property type="entry name" value="PAK1 INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="90"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="137"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="360"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="360"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="427"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="518" mass="53578" checksum="8B2B0B5184D2B5A9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI24</accession>
    <name>C1MI24_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_50407</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055055.1">
        <property type="nucleotide sequence ID" value="XM_003055009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI24"/>
    <dbReference type="GeneID" id="9681160"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50407"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="79" mass="8494" checksum="2F40EB982BE9D8DB" modified="2009-05-26" version="1">MASYITKAGSAAMKAVEVVRTKAIPPAVEYYKATMAKNAEYVVKDPAAVDKLGRQLVFSNLARRVPRPASPARAAGRFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MID2</accession>
    <name>C1MID2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50525</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055647.1">
        <property type="nucleotide sequence ID" value="XM_003055601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MID2"/>
    <dbReference type="GeneID" id="9680482"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50525"/>
    <dbReference type="eggNOG" id="KOG2061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="443682at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298">
        <property type="entry name" value="PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298:SF4">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Programmed cell death protein 2 C-terminal" evidence="2">
        <location>
            <begin position="40"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="166" mass="17862" checksum="BA370E7352D3ED32" modified="2009-05-26" version="1">MAIDADKALPPELRGKGADVSESDLKDLEKMQDKNVVQLSRFHLRLRRSGPTQVVRYSRDAGAAPLWPSVTHAPEHTARTVPPCPRCGAPRTFEFQILPQIINHLKVDSELHSAADFGSAAVYTCSKSCAPPDPGEDGCVVGLDGDLEVSGAYAEEVVLVHPPLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIP5</accession>
    <name>C1MIP5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial carrier family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_4935</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055702.1">
        <property type="nucleotide sequence ID" value="XM_003055656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIP5"/>
    <dbReference type="STRING" id="564608.C1MIP5"/>
    <dbReference type="GeneID" id="9680423"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4935"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WQSERPN"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="135"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="226"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="98"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="307" mass="33007" checksum="A949085FF1040212" modified="2009-05-26" version="1" fragment="single">LLCGGVAGAFSKSCTAPLARITILRQLQSTGVVHGWSGSAGMGIYAALAKIAREEGVRALWKGNGVTVLHRLPYSSINFYAYENIMDFLEGEGSWARSGEKSKSSAGGKGGTSRKDDEDNPERQGGVGLGWDVGRRLVAGGSAGMIACAMTYPLDLVRTRLAAQTTVKHYDGLFHALYVIAKKEGPRGLYRGLPPTLVGVGPSLAINFAAYETFRDHLGIFGEPTMRSLLCGSASAVVSATACYPLDLVRRRLQMRCAQDRGQSFLGVFRAIWATEGMAGFYRGLIPEFCKVVPGVSITYMTYELMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJD2</accession>
    <name>C1MJD2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MORN repeat-containing protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_49414</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Assembles a suppression complex (suppresome) by tethering SIRT1 and MDM2 to regulate composite modifications of p53/TP53. Confers both deacetylation-mediated functional inactivation, by SIRT1, and ubiquitination-dependent degradation, by MDM2, of p53/TP53, promoting a proliferative and cell survival behaviors. May play a role in the regulation of spermatogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Secretory vesicle</location>
            <location evidence="1">Acrosome</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055293.1">
        <property type="nucleotide sequence ID" value="XM_003055247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJD2"/>
    <dbReference type="STRING" id="564608.C1MJD2"/>
    <dbReference type="GeneID" id="9680494"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49414"/>
    <dbReference type="eggNOG" id="KOG0229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GHGRFFH"/>
    <dbReference type="OrthoDB" id="270720at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001669">
        <property type="term" value="C:acrosomal vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052472">
        <property type="entry name" value="MORN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46511">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46511:SF1">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="247" mass="27945" checksum="5273809F22CBEEBE" modified="2009-05-26" version="1">MGVEDDASTSGGVTYANGHIYGAPETLDPADKHGERATVFFPGGAKYKGQWAKNRKHGKGSYTFANGDVYEGEWADDRRTGFGTYWRLDEGRYRVEYNGTWVENKKHGFGVFFNAKGERYEGEWFEGKRHGKGKQTYGGRFDGLGADVYDGEWVHGKRTGRGVMSWANGDAYEGQWEDDQKHGPGTHYYEEKRARYDGVWERDTPRCGEYRAMDDDIAPVIPLPDVKLMDADEVARRAKEVAIDALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJM1</accession>
    <name>C1MJM1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_46471</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056236.1">
        <property type="nucleotide sequence ID" value="XM_003056190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJM1"/>
    <dbReference type="STRING" id="564608.C1MJM1"/>
    <dbReference type="GeneID" id="9681413"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46471"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YRIARIS"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="605"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="639"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="696"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="8">
        <location>
            <begin position="338"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="900"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="909"/>
            <end position="929"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="952" mass="107450" checksum="9712D04D2B4B5C83" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJP0</accession>
    <name>C1MJP0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Inositol 1,3,4-trisphosphate 5/6-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_55039</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ITPK1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055852.1">
        <property type="nucleotide sequence ID" value="XM_003055806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJP0"/>
    <dbReference type="STRING" id="564608.C1MJP0"/>
    <dbReference type="GeneID" id="9681879"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55039"/>
    <dbReference type="eggNOG" id="ENOG502QQS1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="25308at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052726">
        <property type="term" value="F:inositol-1,3,4-trisphosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052725">
        <property type="term" value="F:inositol-1,3,4-trisphosphate 6-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047325">
        <property type="term" value="F:inositol-3,4,5,6-tetrakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032957">
        <property type="term" value="P:inositol trisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008656">
        <property type="entry name" value="Inositol_tetrakis-P_1-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040464">
        <property type="entry name" value="InsP(3)kin_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041429">
        <property type="entry name" value="ITPK1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14217">
        <property type="entry name" value="INOSITOL-TETRAKISPHOSPHATE 1-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14217:SF39">
        <property type="entry name" value="INOSITOL-TETRAKISPHOSPHATE 1-KINASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05770">
        <property type="entry name" value="Ins134_P3_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17927">
        <property type="entry name" value="Ins134_P3_kin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Inositol-tetrakisphosphate 1-kinase N-terminal" evidence="12">
        <location>
            <begin position="14"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp" evidence="11">
        <location>
            <begin position="188"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp" evidence="11">
        <location>
            <begin position="624"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="307"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="523"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="362"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="536"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="576"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH59228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="699" mass="73195" checksum="76A3D38BF56430A8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJS3</accession>
    <name>C1MJS3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_46487</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055870.1">
        <property type="nucleotide sequence ID" value="XM_003055824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJS3"/>
    <dbReference type="STRING" id="564608.C1MJS3"/>
    <dbReference type="GeneID" id="9681637"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46487"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="68"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="307" mass="30730" checksum="9488701DE800ED52" modified="2009-05-26" version="1">MAAADATLAAAREDVKLAEKEASTSGGGGRAAHALKVQARRALKHKIAGLRRDLLLTLGADVNARDDFGVAAIHKAAGHGRVAALDLLLTLGADVNARDDFGVAAIHKAAGHGRVAALVRLLGDGAADVDLKVGEISDAIPAAYGARSRGQTALHVACAKAAAADETSDKTSDKVSSDKVSDKVSDPRIVGALLKYGADVAARDDAGNTPVHDACAACDVRAVRAMMSVVAKRGGGGERGDGRNRNARAAATAENDAGDVPGALVPFRRRGCDARAIWDALREGAASGGGGGGGGGDGDGDGDAKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJU2</accession>
    <name>C1MJU2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55096</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055878.1">
        <property type="nucleotide sequence ID" value="XM_003055832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJU2"/>
    <dbReference type="GeneID" id="9681285"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55096"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="200" mass="21394" checksum="CBCA8808E9D42FD5" modified="2009-05-26" version="1">MEQAGDCIMPGVRVASGFRDALDAVSGRDDDGGGGGGGGGMRWLVDPPPPTPTTPTPPPPPPPTARLMAHPGAKASLRDALVACGVRVDDGDEEDVRVLEDRRSTREGVRTERGLDAPPSPSRARAPARIVIAVGPEGGWTDRERASLIDEGGFEEFAIGAFYTLVPIRPRWRGERRSLRTLPVASLRPPLAFNPRPRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKG0</accession>
    <name>C1MKG0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_55324</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055992.1">
        <property type="nucleotide sequence ID" value="XM_003055946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKG0"/>
    <dbReference type="STRING" id="564608.C1MKG0"/>
    <dbReference type="GeneID" id="9681335"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55324"/>
    <dbReference type="eggNOG" id="KOG0729">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RSKYHIE"/>
    <dbReference type="OrthoDB" id="1937997at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000005">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000037">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048723">
        <property type="entry name" value="OB_PRS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21236">
        <property type="entry name" value="OB_PRS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="202"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH59368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="439" mass="48894" checksum="443C93A35561C345" modified="2009-05-26" version="1">MRKHDRKTDSNGQTGSTPLDKDDIALLKTYGLGPYSGSVRALEADLKDIAKRVNDLCGIKESDTGLTIPSQWDLTQDKQTVQEEQPLQVARCTKIISANTDEAKYMINVKQIAKFVVGLGQHVAPTDIEEGMRVGVDRTKYFIHVPLPPKIDPSVTMMTVEEKPDVTYSDVGGSKDQVEKLREVVELPLLHPEKFVQLGIDPPKGVLCYGPPGTGKTLLARAVANRTDACFIRVIGSELVQKYVGEGARLVRELFQLARSKKACLIFFDEVDAIGGARFDDGQGGDNEVQRTMLEIVNQLDGFDARGNIKVLMATNRPDTLDPALLRPGRLDRKVEFGLPDLDSRTQIFRIHSRSMAVERDIRYELLSRLCPNATGAEIHSVCTEAGMFAIRQRRKTVSEKDFIDAVAKVIKGYQKFSSTAKYLARQICFLSLYFFLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKM3</accession>
    <name>C1MKM3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_46534</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sterol desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056020.1">
        <property type="nucleotide sequence ID" value="XM_003055974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKM3"/>
    <dbReference type="STRING" id="564608.C1MKM3"/>
    <dbReference type="GeneID" id="9681712"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46534"/>
    <dbReference type="eggNOG" id="KOG0873">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VEYYWHR"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="7">
        <location>
            <begin position="173"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="337" mass="37276" checksum="CD138A1B7FFFFBE5" modified="2009-05-26" version="1">MQCRHSLTRAGKGRHRPRARSPPMNTTTSFPVPWVRASSVAVFAAQLLGYVALSSIVEFAYYHRRRGDETSWKCQPRAIRPGDGDGDGDAHRRGSSRKKYAWGLPLLDLFASSSSSSSSSSRGRHPKHATFASLNLLVSALFAGATAEATARGHSSLTSWTAPPLTSLVALVKIILWQSVLEYYWHRAMHAPRLYKRLHKYHHHYKSPRPFDDLFIHPLEAAGYCAILYSSAFVCGEVPIASFLAYMAIMGVCGIIDHCGVRFRVGFGFGFGERNGCGDGDGEKKSISKTITETTGADIGVEVYASRFHDLHHERFDVNYAFPFAFMDALHGTFAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKN5</accession>
    <name>C1MKN5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Basal body protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">BLD10</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_70912</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CEP135/TSGA10 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056024.1">
        <property type="nucleotide sequence ID" value="XM_003055978.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MKN5"/>
    <dbReference type="GeneID" id="9681717"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70912"/>
    <dbReference type="eggNOG" id="ENOG502QT27">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RFQLNEM"/>
    <dbReference type="OrthoDB" id="543507at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051877">
        <property type="entry name" value="Centriole_BasalBody_StrucProt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20544">
        <property type="entry name" value="CENTROSOMAL PROTEIN CEP135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20544:SF0">
        <property type="entry name" value="NUCLEOPROTEIN TPR_MLP1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="197"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="419"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="734"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="828"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="898"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1150"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1287"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1391"/>
            <end position="1490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1501" mass="165022" checksum="1994400A648E281F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLK8</accession>
    <name>C1MLK8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosolic Fe-S cluster assembly factor NBP35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NBP35</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_25310</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. Functions as Fe-S scaffold, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Essential for embryo development.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="8">Binds 3 [4Fe-4S] clusters per homodimer. Contains two stable clusters in the N-termini and one labile, bridging cluster between subunits of the homodimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer and homotetramer. Predominantly homodimeric.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Although plant and algal NBP35 proteins lack the characteristic CXXC motif in the C-terminus, thought to be required for Fe-S cluster binding, they can bind a [4Fe-4S] cluster in the C-terminus. Also, in this linage, no CFD1 partner protein homolog as found in other eukaryotes can be found.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056184.1">
        <property type="nucleotide sequence ID" value="XM_003056138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLK8"/>
    <dbReference type="STRING" id="564608.C1MLK8"/>
    <dbReference type="GeneID" id="9682044"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25310"/>
    <dbReference type="eggNOG" id="KOG3022">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EMDCQVG"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03038">
        <property type="entry name" value="NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028601">
        <property type="entry name" value="NUBP1/Nbp35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF19">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="67"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="376" mass="39793" checksum="6DDFC43FB76B63A3" modified="2009-05-26" version="1">MSTSINDDFSRGPKCPGTNSEAAGNAVACAGCPNKEACQTASTIDPDVLAIRHRLANVKHKILVLSGKGGVGKSTFATQLAYGLSARGAEVGLLDIDICGPSAPIMFGQVGQDVHRSNSGWSPVYVKEGLAVMSIGFLMQNPDDAVIWRGPRKNGLIKQFLTDTEWGNLDFLIVDAPPGTSDEHLSIVQYMKLAGIDGALVITTPQEVALADVRKEINFCAKVGVRVLGVVENMSTMILPVESVQLKFISGPDGDVTEQVRKVLALHFPSPENEVAPSSLSAQVDIFSSNLGAASRMCKWAGVPLLGQVPLDPAIATATERGCSLFSDEVGGRNQNIRNLSLGISPASFEAMKTILDNVICAISEVQSDVFKTGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM74</accession>
    <name>C1MM74_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_56424</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056885.1">
        <property type="nucleotide sequence ID" value="XM_003056839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM74"/>
    <dbReference type="GeneID" id="9682789"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56424"/>
    <dbReference type="OMA" id="ANIARCT"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="8">
        <location>
            <begin position="45"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="255"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="285" mass="30846" checksum="5F00C728FF605AD2" modified="2009-05-26" version="1">MDDAATSYLLVFTASFLANAAIRLVGDACLPSLVGRARWNALTPSQKYALALTPNSMFNSLLAPALVFPALTRTPPLTKRGKFAVITPSVDGDSSNACAVAIGFMAYDLVSMLWNYEASVRSNGKGLFHLYVWHHVLSILFWPVAILNRAFVYFVNWFILSEHSSFWLSLRGSMLTLGTINTPAGLFVQLAFVVSFFGARVAVMPDLYRSYVNADWAAVPGWQATIAAWTVPIPSMLNAYWGFLIVKSLAKVALGGGGKKKKTTGAGPETRARGTAAPMGSPKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMH6</accession>
    <name>C1MMH6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_32482</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TTC21 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057410.1">
        <property type="nucleotide sequence ID" value="XM_003057364.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MMH6"/>
    <dbReference type="GeneID" id="9682366"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32482"/>
    <dbReference type="eggNOG" id="ENOG502QQAB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NATCVRA"/>
    <dbReference type="OrthoDB" id="10259630at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000219">
        <property type="entry name" value="Tetratricopeptide repeat domain 21B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056832">
        <property type="entry name" value="ARM_TT21_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056836">
        <property type="entry name" value="ARM_TT21_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056835">
        <property type="entry name" value="ARM_TT21_5th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056834">
        <property type="entry name" value="ARM_TT21_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056833">
        <property type="entry name" value="ARM_TT21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040364">
        <property type="entry name" value="TTC21A/TTC21B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14699">
        <property type="entry name" value="STI2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14699:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 21 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25058">
        <property type="entry name" value="ARM_TT21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25060">
        <property type="entry name" value="ARM_TT21_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25068">
        <property type="entry name" value="ARM_TT21_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25064">
        <property type="entry name" value="ARM_TT21_5th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25063">
        <property type="entry name" value="ARM_TT21_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25062">
        <property type="entry name" value="ARM_TT21_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B N-terminal ARM repeat" evidence="7">
        <location>
            <begin position="13"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B second ARM" evidence="6">
        <location>
            <begin position="301"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="763"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B fourth ARM" evidence="10">
        <location>
            <begin position="799"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="931"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B fifth ARM repeats" evidence="9">
        <location>
            <begin position="999"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="999"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B C-terminal ARM" evidence="8">
        <location>
            <begin position="1145"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF25068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH59055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1358" mass="150249" checksum="C733AE4966ECB8CD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMK0</accession>
    <name>C1MMK0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_15117</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057419.1">
        <property type="nucleotide sequence ID" value="XM_003057373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMK0"/>
    <dbReference type="STRING" id="564608.C1MMK0"/>
    <dbReference type="GeneID" id="9682381"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15117"/>
    <dbReference type="eggNOG" id="KOG2641">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CIKLIVM"/>
    <dbReference type="OrthoDB" id="5348404at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="330" mass="37411" checksum="F721C1ADB8BC9E67" modified="2009-05-26" version="1" fragment="single">MFEDETTLTWTGFFAFVAVAMSVTQIIMHLHRYTQPAHQRFIIRVIFMVPTYALCSWFSLVDRDASLYLETFRDCYESWVVYNFLSLCLAYVGGPGNVVNRLGGKEIVPSWWHATCCLPRMHVDGPYIRACKRGALQFVFLKPILAMLTLILTWCGVYGDQEIKGDKAYPYIAFVYNLSYTVALYSLLLFYLGAHELLQPYKPLLKFVLVKAVIFLTFWQSILCAILVSDGVLKDGKDGRALQNVLICVEMIIAAPMMLFAFPSTPYADSSKMHGISLKNIGHAISLNDVVSDTVHQFAPTYQEYVLHGTEGGAARKYRMKTHVLMGQEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNG0</accession>
    <name>C1MNG0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid scramblase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55882</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phospholipid scramblase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056644.1">
        <property type="nucleotide sequence ID" value="XM_003056598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNG0"/>
    <dbReference type="GeneID" id="9682538"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55882"/>
    <dbReference type="eggNOG" id="ENOG502SBRB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GCSELCC"/>
    <dbReference type="OrthoDB" id="191150at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017128">
        <property type="term" value="F:phospholipid scramblase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005552">
        <property type="entry name" value="Scramblase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248:SF9">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03803">
        <property type="entry name" value="Scramblase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="315" mass="34668" checksum="3E525AD4ECAF8334" modified="2009-05-26" version="1">MPIMDAVPLLDSATATILASVNKYTIQQHVKWLDNCIEMPNTYTVYNFQTARPRLETNNQAIMRINEVSDGCTRCCCAPNHSVVLNFDALDPSGRELFPVMTMERQGCCGKLCLGEIVCMECCANEAFFHAGKVEGKAGELDKSRVFGRAKVPIPFAGGFTPVIQVMDRDATSDHHFASVKGPMCFGGCSELCCSVPFTVKKVNKDGSISVNVGDVATITKMKPKSFADAMRELLTDSDLYELEIHDLSLSAQQRASLVGTLLLCDYMFFERDIDACSYNVFTKELKISLCNCFCLGKIIPCQCTCGGDDKERDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNH9</accession>
    <name>C1MNH9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55906</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057107.1">
        <property type="nucleotide sequence ID" value="XM_003057061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNH9"/>
    <dbReference type="STRING" id="564608.C1MNH9"/>
    <dbReference type="GeneID" id="9682138"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55906"/>
    <dbReference type="eggNOG" id="ENOG502QPV8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TMPHEKY"/>
    <dbReference type="OrthoDB" id="2538345at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689:SF1">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="397" mass="44631" checksum="519629999ABD5B06" modified="2009-05-26" version="1">MEYSRYKAGEDDGRAAAKSMVEKHAEAQKNAMQEACLGALRRAMPAASAETCLAALRGTDWDADKAYHQLKSFMSTESGAGGGGGGGGGRKRKKARRDRGGSSSDSDDSDSDGSSSSSSSSSSRSRKKSKKKHKKRGKSGKKKERESKKKSSKKESKKKDGNKEKRRKRDRDDGDGDGKAKRAMMKTRGAGETASHTTPFAWCTPFLEDFSRRHSSPALPFQRLTGRGAAAGPETSFGARGFLKETDKYDKEAEFRAWVEEVKGMSTESLQKWEERELFKEFAEDYNTSTLPHEKFYDLDKWGREEAARRAASGGEDKEERTAFDDEKERKREIEIERARRTAEYKREAYDKMKSSGDLENFREQVRLKELRTHAYNTGDVKTLAMVNKKLEPEEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNI2</accession>
    <name>C1MNI2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_55909</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056656.1">
        <property type="nucleotide sequence ID" value="XM_003056610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNI2"/>
    <dbReference type="STRING" id="564608.C1MNI2"/>
    <dbReference type="GeneID" id="9682548"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55909"/>
    <dbReference type="eggNOG" id="ENOG502QT3S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RTIGCEA"/>
    <dbReference type="OrthoDB" id="5914890at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24073">
        <property type="entry name" value="DRAB5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="361"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="417" mass="44310" checksum="2E3BF00D6E2BCEC1" modified="2009-05-26" version="1">MNLLGTVARRFSPLRDELISNDADHCAAREAPRTMSSSLAPERVPKVRVAVVGDTGCGKSSLVRLMLESGEPGATTSYSTTRRRGGSRLPDRTIGCEAEVRVLHHPPPGASGDSTPRPHFVEIFDIGGHDEYKGERSVFYDELDGVVLVHDLSFRGSAKKLERWAREIAATGTFAPAASTPQWNAAPGTPLAMPPSSSNVLHGFGGLPVPALVVANKADLHKRRRDDESDDRGGKGGARRRRRRFPSFGGDENEIPGDGIVTFVKRLWERVAVALHLPRTVARKVTRRVASFGRLDGALLPTHVGDASDPNAPGAAWTDARAGYAGLSVGSGLRCVATRGRMDRAVVDAFFHELLTRRFGGEGAGGASSSSSSSRGTTYGTAGFASGSTDAQLRGAPRSQWMGGDRVDAGVHGDNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNM5</accession>
    <name>C1MNM5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14">Histone acetyltransferase</fullName>
            <ecNumber evidence="3 14">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MICPUCDRAFT_45330</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3 14"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056673.1">
        <property type="nucleotide sequence ID" value="XM_003056627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNM5"/>
    <dbReference type="STRING" id="564608.C1MNM5"/>
    <dbReference type="GeneID" id="9682574"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45330"/>
    <dbReference type="eggNOG" id="KOG2747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DSPEGNN"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000022">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.60:FF:000001">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000002">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025995">
        <property type="entry name" value="Tudor-knot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF161">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11717">
        <property type="entry name" value="Tudor-knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="16">
        <location>
            <begin position="159"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="13">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602717-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEH58318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="447" mass="51930" checksum="6B9B3DE4FBB4E38D" modified="2009-05-26" version="1">MTGKENDTPKTEKQDGEEKQEKKAHHTGGNARPPVDTSLLPPKPKEEDVVKVKHAASGVMLPLDVGARVSCRWRDGQMYPVRVIERRAGPKGVLGQEEYEYYVHYEQFNRRLDTWVTIADMDLDTAETDDDKKKRKAEEVDEEHADFDPNALREHEECTKVRNILSVELGRHQMDTWYFSPFPPEYTTCKKLYFCEFTLNFFKRKEQLQRHLRKNEMYHPPGDEIYRNETRGRTAAFFEIDGKKDKIFCQNLCYLAKLFLDHKTLYYDVDLFLFYVLCEVDERGYHIVGYFSKEKCSEEGYNLACILTLPAYQRKGYGKMLISFSYELSKKEGKVGTPERPLSDLGLVSYRGYWTRELLAILKDPSRAVMSIKDLSELTMIKTEDIISTLQHLNLLAYQKGAYVICAAPEIIEKHLKEAGSPGVEVDPSKLIWTPYNAEKEYQNFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNS4</accession>
    <name>C1MNS4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_56010</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC10 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056696.1">
        <property type="nucleotide sequence ID" value="XM_003056650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNS4"/>
    <dbReference type="STRING" id="564608.C1MNS4"/>
    <dbReference type="GeneID" id="9682600"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56010"/>
    <dbReference type="OrthoDB" id="125856at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048625">
        <property type="entry name" value="Sec10_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20667">
        <property type="entry name" value="Sec10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec10 N-terminal" evidence="7">
        <location>
            <begin position="75"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec10-like alpha-helical bundle" evidence="6">
        <location>
            <begin position="193"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="208"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="253"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="366" mass="39848" checksum="6DE6A3DBC7A1DBDF" modified="2009-05-26" version="1">MAPPPPRPASEDEFKARLSPATARADGRIPADDFSVSEYVASLVRPLLPTTETPLERVTVDDVYPVAGAMLDRLELAREKLVNLERVHAMRAASLSARARKEEKALERAADGLKSGVGALSTALDAIETRVSHVASRTGRVGERLRVADAQRLATTDAVSLATHLAAFNACESFEDLRLHVDPLFYDQTRSPEAARLAQRLLRVATEAAESERARRKKTALAEAARVHRRRPPGTGPRPGGAGASSSSIVDEVDAKSRRRERGEDAGGGPKPLALARAIDNLERYCDQLENDVLLAFAEAEDEGDLRAMKRAAKTLSRFNQGSSLISRFIATRPMFMSVDAVNEIEARSPSHWFPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNY6</accession>
    <name>C1MNY6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_56078</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056726.1">
        <property type="nucleotide sequence ID" value="XM_003056680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNY6"/>
    <dbReference type="STRING" id="564608.C1MNY6"/>
    <dbReference type="GeneID" id="9682632"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56078"/>
    <dbReference type="OMA" id="RQDVYSE"/>
    <dbReference type="OrthoDB" id="10663615at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043597">
        <property type="entry name" value="TPH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13868">
        <property type="entry name" value="TPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trichohyalin-plectin-homology" evidence="4">
        <location>
            <begin position="124"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="123"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="339"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="440" mass="51081" checksum="43A5AC1D5469C508" modified="2009-05-26" version="1">MVLSTSDRRMFINGEPKPERPRVPATTRAGATLPKRTSSSVAAAKKKPAPPPPEPPEFDASWPKMPSEMPPAEKPTEPLRERDDHRTTRDWAIMSRFEREVHARQEAEVKEEKRRATIEQKAYLDSQIEIQRLRVEKAREEKKRLAEAVAADVAKYKQEELVKERRRRAFEAEVKAEQDRMMAELEEKRRAAVAAKKAEEDRALREIQEQLESEAMAKAKKIEDAKTAYARTMRFNEEQKLIKLAEQKRVAEEELRVAAQYDEMLEAQERAREQAMADFHARIAARAGKAGEKVAEQSAAKEAEEHARMLKFHEEREDAMRAKENAVKAKKADATAKQLEMLSLQLDLQREEKEKIKADAMRYAEEMKEREAKLKAEDEEKKTARRRAAVMNRLELERQMTEKLDRRIAEHDDNMNEEELRFNSAILDQAKAVVLEREEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP19</accession>
    <name>C1MP19_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56115</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057207.1">
        <property type="nucleotide sequence ID" value="XM_003057161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP19"/>
    <dbReference type="STRING" id="564608.C1MP19"/>
    <dbReference type="GeneID" id="9682184"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56115"/>
    <dbReference type="eggNOG" id="ENOG502RZFS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AFYCKAG"/>
    <dbReference type="OrthoDB" id="9988524at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF1">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="367" mass="39083" checksum="4646EF4231DDC67A" modified="2009-05-26" version="1">MASTSATSASRAALRSSPSSRRRRDAARVAAPPPRAAAKGGGLETGARDDVVSVSLESVLNFRDLASAGGSIAPGRVFRTATPGNASEADAAIVLNDLGVKRLLDLRSEDEFEADPGPLQSAFPEIISFTRNVDGVDDPLLRKYGKEAYDAYLRRQSDAAFLDGIDDATRAGALVRYHAPLLEYERYYLAIYDRLTAVEKVKAAVFTAQAFLYDDTNQKELFVGKVNAGGLPLLNEVMVDGSGPEIRAALKVIAKSTAAAPTAFYCKAGKDRTGLVAALTLHCAGLSEDEITEDYHKSEGTGKAALGGGRIERGVNIDYSRFYGSPKAVMEGVLAYVKTNHGSVDGYLDSIGFDASDREALREALCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPH9</accession>
    <name>C1MPH9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Katanin p60 ATPase-containing subunit A1</fullName>
            <shortName evidence="8">Katanin p60 subunit A1</shortName>
            <ecNumber evidence="8">5.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">p60 katanin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">KAT1</name>
        <name evidence="8" type="synonym">KATNA1</name>
        <name evidence="12" type="ORF">MICPUCDRAFT_16445</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.</text>
            <dbReference type="EC" id="5.6.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
            <location evidence="1 8">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.1" evidence="8"/>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057580.1">
        <property type="nucleotide sequence ID" value="XM_003057534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPH9"/>
    <dbReference type="STRING" id="564608.C1MPH9"/>
    <dbReference type="GeneID" id="9683034"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16445"/>
    <dbReference type="eggNOG" id="KOG0738">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KGRWQQV"/>
    <dbReference type="OrthoDB" id="191529at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008568">
        <property type="term" value="F:microtubule severing ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051013">
        <property type="term" value="P:microtubule severing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21748">
        <property type="entry name" value="Kp60-NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000025">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000159">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03023">
        <property type="entry name" value="Katanin_p60_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028596">
        <property type="entry name" value="KATNA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048611">
        <property type="entry name" value="KATNA1_MIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF19">
        <property type="entry name" value="KATANIN P60 ATPASE-CONTAINING SUBUNIT A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21126">
        <property type="entry name" value="KATNA1_MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="230"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="90"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="238"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="484" mass="51539" checksum="5F15B5602C8EFBD9" modified="2009-05-26" version="1">MSLAGLNAAADQLTIAREHAMLGDYDTARVYYQGVISQVARHCRAVGATSGAGASASDAHRARRWLGAQSQLNDELESVAALAAERAVFSARPGTASSPSLSREGGRFIHLPGSPSRAPRATPPPDLTWMGGGAAGKAGQQHHGGGGGGGGAKAALKSPRDRDDRGARNAPQHVGPDGDLADGLSRDILDKSPSVRWDDIAGLEDAKRLLEEAVVLPLLMPDYFQGIRRPWKGVLMFGPPGTGKTMLAKAVATECGTTFFNISSSTLASKYRGESERMVRILFDLARRHAPSTIFIDEIDSLCTSRGAAGEHEASRRVKSEFLVQIDGCSGGGGGGEDGASTAAPVMVLAATNFPWDIDEALRRRLEKRIYIPLPDRAARSALVNINVSGVEVADDVDFDALSESMNGYSGDDITNVCRDAAMCGMRRKIVGKKPEEIRAMSREEVAAPITMSDMTQALRRISPSVSKEDVERHMEWLAEFGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPZ7</accession>
    <name>C1MPZ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_39224</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057672.1">
        <property type="nucleotide sequence ID" value="XM_003057626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPZ7"/>
    <dbReference type="GeneID" id="9683475"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39224"/>
    <dbReference type="eggNOG" id="ENOG502SCZE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AYCTTRN"/>
    <dbReference type="OrthoDB" id="204795at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIT" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="261" mass="25976" checksum="6B5E1F964DAD6AB9" modified="2009-05-26" version="1">MPCQAAIDFASKAVEADNDGDIARAIELYDKAAAALDDAANAAPADEAASMRAKATEYRARVAKLQPKLQAEKMAAMASGAAALQQGATVASQAQKGVSTAGGYSTMAGAGAVAAVAGLAVVGPITAVAAGTAAVYATTRKDNIGDIARTTGKYTASAASAAKAFNDEHDVTGKLYECGKTAAAKLKEANQKYGITGRLFSAAKTGAAKAKEINEKHDITGKVGRGAATGLTKATELMGGGAPGGDDGEKLKADALPSAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ12</accession>
    <name>C1MQ12_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_67210</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the BCD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057679.1">
        <property type="nucleotide sequence ID" value="XM_003057633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ12"/>
    <dbReference type="STRING" id="564608.C1MQ12"/>
    <dbReference type="GeneID" id="9683483"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67210"/>
    <dbReference type="eggNOG" id="KOG2858">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NITRSRM"/>
    <dbReference type="OrthoDB" id="272357at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070761">
        <property type="term" value="C:pre-snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048254">
        <property type="term" value="P:snoRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23023">
        <property type="entry name" value="zf-HIT_BCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051639">
        <property type="entry name" value="BCD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057721">
        <property type="entry name" value="BCD1_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483:SF3">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25790">
        <property type="entry name" value="BCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="9">
        <location>
            <begin position="22"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH57630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="318" mass="34721" checksum="ADCE670AA24B0959" modified="2009-05-26" version="1">MAEAEVETEPPAPAPPSRMGECQVCEGEEKNPGKYRCPRCGTVTCGLACSKAHKTRGEGCNGKRDRAAFKDIREFSDADVVSDYRFLEETLLEKDRAKRWRPQYADGSDAAARSERAPASRKVIALLTQQAKARGTTLLCMPDGMARRVANTTFYDRRRDVLQWRVEWLFHGISSASAVEIPDANDDADADAAADAVAAAAAAAAKAVDEKVDDTTTIAAALRRHFEQGPGRAARLHQLRRFTDALKALDKGDGGGASICVYFEKHGCPANAKRYHRLSLENTFKENLAGKNVLEFPTLHVAVLPADAGKFLEPEEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQC8</accession>
    <name>C1MQC8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_57243</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058106.1">
        <property type="nucleotide sequence ID" value="XM_003058060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQC8"/>
    <dbReference type="STRING" id="564608.C1MQC8"/>
    <dbReference type="GeneID" id="9683172"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57243"/>
    <dbReference type="eggNOG" id="KOG0034">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45942">
        <property type="entry name" value="PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="70"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="106"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="289"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="374"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="531"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="390"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="540"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="554"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="658" mass="70366" checksum="C769649AF070038B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQR5</accession>
    <name>C1MQR5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Anion exchanger family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AE_1</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_47080</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anion exchanger (TC 2.A.31.3) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058172.1">
        <property type="nucleotide sequence ID" value="XM_003058126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQR5"/>
    <dbReference type="STRING" id="564608.C1MQR5"/>
    <dbReference type="GeneID" id="9683610"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47080"/>
    <dbReference type="eggNOG" id="KOG1172">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ADAFNYR"/>
    <dbReference type="OrthoDB" id="1735926at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005452">
        <property type="term" value="F:solute:inorganic anion antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050801">
        <property type="term" value="P:monoatomic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.570">
        <property type="entry name" value="Helical hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011531">
        <property type="entry name" value="HCO3_transpt-like_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003020">
        <property type="entry name" value="HCO3_transpt_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453">
        <property type="entry name" value="ANION EXCHANGE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453:SF127">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 4 MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00955">
        <property type="entry name" value="HCO3_cotransp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01231">
        <property type="entry name" value="HCO3TRNSPORT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="528"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="7">
        <location>
            <begin position="66"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="7">
        <location>
            <begin position="241"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="573" mass="60974" checksum="967989DC9992D41E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR87</accession>
    <name>C1MR87_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57567</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057889.1">
        <property type="nucleotide sequence ID" value="XM_003057843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR87"/>
    <dbReference type="STRING" id="564608.C1MR87"/>
    <dbReference type="GeneID" id="9683327"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57567"/>
    <dbReference type="OrthoDB" id="547106at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005082">
        <property type="entry name" value="Peptidase_U9_T4_prohead"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03420">
        <property type="entry name" value="Peptidase_S77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="351" mass="39473" checksum="FEE1A635597B1098" modified="2009-05-26" version="1">MGACCSVPVTGDGTTETDNRVRRERTENSLFWNDDRLIVYGILARADAKNRNGRVYPRSLLKRETVAFENAHLRHDRALGELDHPPPTSPTFRSLNRENISHQVLDYHWEGEDLMGHVEVLPTKSGNMLRSLYLAGHQLGMSSRGWATLKEREGFTYLDSDFELITFDFVSDPSTEGAFLRPLQRRYEKLKPQIDIDEKFESFIRFCADVNEHGAAPARVKGDEAHLPRGRNAPAMSASSSSSAAAMRAGSVPKELPPVPGAVAIACEETGGEVLMTGREFMDETAWDEESYYESEEEEWMPSPTPQELRAKEAAAAARGGWWGRKKKNKVVPLKPTLSLRDSFDRLPKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRH0</accession>
    <name>C1MRH0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57650</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058307.1">
        <property type="nucleotide sequence ID" value="XM_003058261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRH0"/>
    <dbReference type="GeneID" id="9683745"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57650"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="351" mass="37950" checksum="D288193B7FFFFE2C" modified="2009-05-26" version="1">MGSLLFGWDTPHDPPRPGSRVPQGAAPTPSRSSVVDAPPHSCARPGYVKCEAARIDRLARGETATAAETRATEDEDEETATEAMLRDVRLAAWHRILGDARTRAGEEEPRASAEPRATSTSPPRVDDAALAGVAAATNVHDGNVRAMDALTLVNASSAARASEPKVRVSLTVVVERAAPRRRRRRRRRRRLAAGRSSGTRSRAAGCRRGATIAISRAISPPRSPPPPPPPPPPPKSSERVQVSLQVVDARDSKASVAARGAFVRVVNEVIRRARVKEREERDATDDDRAHWWRGTRSALLNAPPSTARDGGRGPERWGGGGGFTPQFMQDTTLRWDGEEEEEEEKRADAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRJ4</accession>
    <name>C1MRJ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57675</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058317.1">
        <property type="nucleotide sequence ID" value="XM_003058271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRJ4"/>
    <dbReference type="GeneID" id="9683377"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57675"/>
    <dbReference type="OMA" id="AGRITCG"/>
    <dbReference type="OrthoDB" id="2014733at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33874:SF4">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33874">
        <property type="entry name" value="RING FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="299" mass="32820" checksum="AF84F74537DC52C4" modified="2009-05-26" version="1">MDDESGARAPRSPSPLGYDDATARRAGVDDDDDATASSSRLQQQKQQHRELALGHLQRTVNRFKARLLRFNAVDSASSYLRGLLSTPEGTREVYARLLARIETPVFLKNLENRRRRRDDDEDDDEDAVDEDDDDAPIFDVMDPNWWENATTTTTTTTTTDALVEIQDAVPTTTNLNLNANATARDSDEPGWVVVSRDDAVDAVADFVAAFVSSHPAAADYPPEKMQRALASALRDLQTRGNKTNARRLWDCGVGVYRGCHWTYSAAATATNPLVAQLVLGAVYTSARVACGVASMFVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSH5</accession>
    <name>C1MSH5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58488</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059054.1">
        <property type="nucleotide sequence ID" value="XM_003059008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSH5"/>
    <dbReference type="STRING" id="564608.C1MSH5"/>
    <dbReference type="GeneID" id="9684493"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58488"/>
    <dbReference type="eggNOG" id="KOG3082">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10268103at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.170">
        <property type="entry name" value="Formyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138:SF5">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="2">
        <location>
            <begin position="136"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="296" mass="31222" checksum="608BE5594FF58389" modified="2009-05-26" version="1">MSSFAAAKAGLRAFRTSGSGIVREAMSTRAWASSRCVAATAASTGHPHHHHHHHHRHLHRSPRSGHAPGPSDAARHRRPLRVIATTTTSSARGVGGVRNVSARASSSSPSPSDEEGGGARKHRLVFLGTPDVAAGALSAIFDAAETPDAAFEVHAVVSQPGRPRGRGRKSSGPPPPSPVAALAATRGVPEDFILCPVKANEPRPRRLSTSTDAFELHPDIRLQDDFLATLRAMDVDLMVTAAYGNFLPQRFLDIPRLGTLNIHPSLLPQFRGAAPVQRALEAGVDVTGVSGAYSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSK6</accession>
    <name>C1MSK6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57727</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058696.1">
        <property type="nucleotide sequence ID" value="XM_003058650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSK6"/>
    <dbReference type="STRING" id="564608.C1MSK6"/>
    <dbReference type="GeneID" id="9683802"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57727"/>
    <dbReference type="OMA" id="EIDEHEC"/>
    <dbReference type="OrthoDB" id="514951at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="190" mass="21942" checksum="94E49C7B95D0C6FB" modified="2009-05-26" version="1">MSAADALTQDDWVPAQEVFESGADFRFAESARMCRKRMREIEERDANGEEDMEEEIDEHECERLRKAARPTYEQVVGKASGRAWKPRAEKRAASFMKPQTGGMKTWAQKMEEKAKKKAFATEMRSRQDDARAARKKEHERLAAKKKQKQENVMKTGLGNFKDQVTTQATVAKRSRKNDKRVKKQKALKMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSV2</accession>
    <name>C1MSV2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_57834</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RENT3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058745.1">
        <property type="nucleotide sequence ID" value="XM_003058699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSV2"/>
    <dbReference type="STRING" id="564608.C1MSV2"/>
    <dbReference type="GeneID" id="9684184"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57834"/>
    <dbReference type="eggNOG" id="KOG1295">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WRARVEY"/>
    <dbReference type="OrthoDB" id="18087at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039722">
        <property type="entry name" value="Upf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005120">
        <property type="entry name" value="UPF3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112:SF0">
        <property type="entry name" value="FI21285P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112">
        <property type="entry name" value="UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03467">
        <property type="entry name" value="Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF3" evidence="6">
        <location>
            <begin position="3"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="170"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="417" mass="42689" checksum="B7ED95CAFB1EEDDA" modified="2009-05-26" version="1">MPRTKAVVRNLPPDQDASSFFASVDASGFDGTTCAYRDFVQGKRKTRVVIPSVAHVGFDTERALFDFAAAFDARAYDDAFGGEWRARVEYAPYQKIPRLKPRLDKREGTIERDADYKKFVEKLAEDPVAMQSAEVLLDRREREKKALERANGGKAPVRLSALMKHLIAKREAERSKLERKKKKAKARKEKAAAGGGGGDRTGGGAGGTAEDERTLGKKAKKWARKKAKEAEAAAAAAAAGGKSNANAAGGGGKGKRPDASEKQTQKLMRRMTVNDGGGGDRTAGGVPKPKSGSGKRAGGGGKGGDGGDAAQTPAAMKTPKILARPQTTSTAPAPANGGGGGVGASKPSKKKARPDVQIYVAPGARKGDGGGGGGGGGGGGEKGGVSAPKPGGGGGGGNKKHKHPPRAKGAVPAPKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSZ5</accession>
    <name>C1MSZ5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57882</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058407.1">
        <property type="nucleotide sequence ID" value="XM_003058361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSZ5"/>
    <dbReference type="STRING" id="564608.C1MSZ5"/>
    <dbReference type="GeneID" id="9683865"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57882"/>
    <dbReference type="eggNOG" id="ENOG502S3NK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IKPRTHI"/>
    <dbReference type="OrthoDB" id="10265748at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="71"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="206" mass="22519" checksum="C9BC718A9C979AC0" modified="2009-05-26" version="1">MGKSGKSPGGGRAPPTEKTTSPWPSDVTYLTSLHYGDDVKRAKEIYAKYRVSGDDPILASAASTKKIARWQRIVDANHPARGEHGLFASRKLERGERIVDYLGHVSLRGNESQTSDYTASFGDAHELALDAEKMGNEARMINDFRNTGKRANALFDQYVDAAGDTKLGVFVGPHAIGKGEEILVSYGKGFWRNRVGDMSAFTGHDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT76</accession>
    <name>C1MT76_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_11550</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058818.1">
        <property type="nucleotide sequence ID" value="XM_003058772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT76"/>
    <dbReference type="STRING" id="564608.C1MT76"/>
    <dbReference type="GeneID" id="9683876"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11550"/>
    <dbReference type="eggNOG" id="KOG3138">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EYAGAIC"/>
    <dbReference type="OrthoDB" id="47374at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="124" mass="13942" checksum="B6D3771A2C8B0AA8" modified="2009-05-26" version="1" fragment="single">DKFYVECAAAGKTTQLAYVGDELVGAIACRLELTPEKDAARQYIMIVGVYAPWRDRAIGTRLLKHALNEGSKDPFIKQAYLHVQTNNDDAIAFYTRFGFKRNGVALNYYKRLDPPDAAILELDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT88</accession>
    <name>C1MT88_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57975</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058446.1">
        <property type="nucleotide sequence ID" value="XM_003058400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT88"/>
    <dbReference type="GeneID" id="9684261"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57975"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="123" mass="13266" checksum="D5C6C34D8BA5385A" modified="2009-05-26" version="1">MKLAEEVSELKDSIDAGAGDADKDAAVKRAMETQRASQATIKSLESEVRALQTKLRMMEAHKAFAASDEDDARRALESAMMLFALAMTLLVFLGVSEWAGWTDVIGWVARSKLGDGGGECRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTD1</accession>
    <name>C1MTD1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_33509</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpX chaperone family. HslU subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058844.1">
        <property type="nucleotide sequence ID" value="XM_003058798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTD1"/>
    <dbReference type="STRING" id="564608.C1MTD1"/>
    <dbReference type="GeneID" id="9683906"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33509"/>
    <dbReference type="eggNOG" id="KOG0745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YGMIKTD"/>
    <dbReference type="OrthoDB" id="1721884at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004491">
        <property type="entry name" value="HslU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00390">
        <property type="entry name" value="hslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003544">
        <property type="entry name" value="PRK05201.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF3">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE ATPASE SUBUNIT HSLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="180"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="7">
        <location>
            <begin position="471"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="81"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="590" mass="63310" checksum="8D711D16440E1C63" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTJ6</accession>
    <name>C1MTJ6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58096</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058501.1">
        <property type="nucleotide sequence ID" value="XM_003058455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTJ6"/>
    <dbReference type="GeneID" id="9684314"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58096"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="188" mass="19193" checksum="8F59ED84D4804E1E" modified="2009-05-26" version="1">MPRGADRYLARGSVEDDPRTRRSEDLTTTTATATATPPRMGAMPVAPNPSRDVPPLESRPLEGGASSGSDDETPRSPATPRRARRLASDRQISALEDGNGNASSQNDPPPASGPGGDARDAAATTSRRARCGSAASVDSVISSVGSVGSGFTTEDEWTGGGLFPGAPGLGGGLRCVLYTGPHTTAFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTR5</accession>
    <name>C1MTR5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Glycosyltransferase family 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_58523</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059365.1">
        <property type="nucleotide sequence ID" value="XM_003059319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTR5"/>
    <dbReference type="GeneID" id="9684805"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58523"/>
    <dbReference type="eggNOG" id="KOG3916">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="508846at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008378">
        <property type="term" value="F:galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003859">
        <property type="entry name" value="Galactosyl_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027995">
        <property type="entry name" value="Galactosyl_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19300">
        <property type="entry name" value="BETA-1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19300:SF30">
        <property type="entry name" value="BETA-1,4-GALACTOSYLTRANSFERASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13733">
        <property type="entry name" value="Glyco_transf_7N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02050">
        <property type="entry name" value="B14GALTRFASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Galactosyltransferase N-terminal" evidence="13">
        <location>
            <begin position="252"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Galactosyltransferase C-terminal" evidence="12">
        <location>
            <begin position="382"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="92"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="200"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH56497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="451" mass="48245" checksum="C6E8330CDF82D338" modified="2009-05-26" version="1">MASEPRRFVQGVPLGKPPPHVGPQPRARRDSANGWARSSRCKGGRARQAATIALALACVLVARRVVGGSFAAGEGIVASSSSAATRVAARASASERREALLRSREARGGAGDGATSDRGVDDNETAALPPLIKRACDCPECPSSSPSISSEKPSCDARVRDVEARANAWLSEVKARAERLTTLAKTDACAACGVPSHLAATESESSSSSGAGGGSARGGDADADAPLPLPDLLATTRASAPSPPAPGTRRQKEVLGVCVPYRDRRDQLEVFSAYMKQHLDAQGVPFKIYVAEQSNQSAFNRGWALNAAFMNAERDGVAYVVMHDVDMLPLRYLNDVDSFRAAPVHTAPRTVILGVNYRYDDALRRGGDVAHLSTEASQFAHRGYLPYPKYCSGAFMSTTAFYRAINGHSAKFWGWGGEDDEFCARVAKYKARSYLHWSPYDRVRAVNAVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTT1</accession>
    <name>C1MTT1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_7821</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059078.1">
        <property type="nucleotide sequence ID" value="XM_003059032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTT1"/>
    <dbReference type="STRING" id="564608.C1MTT1"/>
    <dbReference type="GeneID" id="9684516"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7821"/>
    <dbReference type="OrthoDB" id="496510at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47444">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47444:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="96" mass="10494" checksum="B83BE636FB0A350A" modified="2009-05-26" version="1" fragment="single">GGAGNKAREISSMEAMIRGDANQPWNEDLPGGGQHYDVFTGRHFESAEALARHQKTKQYKRDRKRVLNGPKPHEQGDAEAAAGMAPPDNGKKLNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTU4</accession>
    <name>C1MTU4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_58554</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059082.1">
        <property type="nucleotide sequence ID" value="XM_003059036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTU4"/>
    <dbReference type="STRING" id="564608.C1MTU4"/>
    <dbReference type="GeneID" id="9684550"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58554"/>
    <dbReference type="eggNOG" id="ENOG502SZ6A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF17">
        <property type="entry name" value="PROTEIN MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="14"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="229"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH56214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="344" mass="36744" checksum="39CC586F5A3ED36F" modified="2009-05-26" version="1">MSAALGWSRAASPSANRFHGATTPSRAAAAASPSPRCGVGSRPLGKRDTNVVVVVGRRRGDGRGRARGPHPPRAAFPIFLPLSEWNYPGLASDAAVAVASYIVSDLIAQSSERKVAASSVDTRAPALVDPSPSAPALATWDARRLRRYATFGAMDGVFSHGWYTWLDDAVATWPGVATWPAGGVAGGIENANAAGLRVAESIVADMTIFAPMWCAAFLTTMAVLAAKDGHEEEEGKEEDGVRGDAPPTRRAENAPDETWWQSAPRAARKRLKEEWFTLYAADAAWWIPADVIVYGVAPVQFRVGTYAAINVVYTALLSLWAEKKLLKELALAKALSREEETSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTU9</accession>
    <name>C1MTU9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58559</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059085.1">
        <property type="nucleotide sequence ID" value="XM_003059039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTU9"/>
    <dbReference type="GeneID" id="9684559"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58559"/>
    <dbReference type="eggNOG" id="ENOG502S2PD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="199820at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="281" mass="30400" checksum="8B6F95E230C3005C" modified="2009-05-26" version="1">MRTITAAPARVHAAPLNVARRVVSKPGPRRASAPSTRSSDRKSARTCATEMTSTSTTAGNDAVLVAEDLDLDAPNPSAIYDVVDEDEMLYGASNTFPIKPDELVAKCKSALRAGFANIGDELAEDFEFIGPVVGPLPRDAFVNAVGGFDLTTGFPDMKSNYHHFRVDPFETNRVWFQNRTTGTHAGKLAGRFEATGTKVECPPQALSMTFNESGKITKITVGVVMDRTIGNTGGLGGVFGLFNAIGSPLPFPEGRPWKMSKRYKFFQWLGRLSAKRADPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTW3</accession>
    <name>C1MTW3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58577</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TOM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059093.1">
        <property type="nucleotide sequence ID" value="XM_003059047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTW3"/>
    <dbReference type="STRING" id="564608.C1MTW3"/>
    <dbReference type="GeneID" id="9684829"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58577"/>
    <dbReference type="eggNOG" id="KOG1087">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2018246at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03561">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044836">
        <property type="entry name" value="TOL_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45898:SF4">
        <property type="entry name" value="TARGET OF MYB PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45898">
        <property type="entry name" value="TOM1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VHS" evidence="2">
        <location>
            <begin position="18"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="149" mass="16910" checksum="34FAF54C7ABEE342" modified="2009-05-26" version="1">MAPRDKVKNPAYQLVDKATYDHLPEPDWGVCVDLCDLVNAEFPTYGKDAVKALKLKIQKRHRPNAQSFAFTTLETCMKNCGARFHHMVIAKDVLGEMMRLVLGGKLQPEVRTKILELVEEWATQLPIHQARSISHWSPYDRVGVVDADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUF4</accession>
    <name>C1MUF4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58787</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059186.1">
        <property type="nucleotide sequence ID" value="XM_003059140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUF4"/>
    <dbReference type="GeneID" id="9684927"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58787"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="54"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="394" mass="40998" checksum="638F129454C510F6" modified="2009-05-26" version="1">MYGAASAHAAAMERRRAATAASASSSSAGGGLAGGGGGGPPRSIASALPHGAAPRLPSFRHADRPRLRALHTTCAVLLDMLGDDKGLGVGDALFLPGEAWRDADRGADAVADAREYAREEILDACAKDARARGIAPGVLSTLILELLRELDDSLLTGKLHEAFAAAVKIKDYRSRLYVTRLLLDRLPADRRAALDALVRVLARVAPRLDAPRSPSSSRATSSSRDVAMDAKDYDALVKTMAPGVLRRKGGGGGSPPKAQGGAPGPRRGLAADILFDGIEDGKRAAKLLKDIVRERLYLLDKAAVVVGEDDDGYAAGSAASAARKGGKERGDDDDAWFGYASATKAARPPQAGGSASSSSSPGDRENVEPNPVLRVKTKLRCVLYTGPHTTALAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUS7</accession>
    <name>C1MUS7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TWY3 methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_58919</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36635"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="Rhea" id="RHEA-COMP:10379"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73543"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.1.1.282"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36355"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.5.1.114"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059245.1">
        <property type="nucleotide sequence ID" value="XM_003059199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUS7"/>
    <dbReference type="STRING" id="564608.C1MUS7"/>
    <dbReference type="GeneID" id="9684991"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58919"/>
    <dbReference type="eggNOG" id="KOG1227">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NVFFREL"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102522">
        <property type="term" value="F:tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000131">
        <property type="entry name" value="tRNA wybutosine-synthesizing protein 2/3/4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1960.10">
        <property type="entry name" value="tRNA wybutosine-synthesizing-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003827">
        <property type="entry name" value="tRNA_yW-synthesising"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036602">
        <property type="entry name" value="tRNA_yW-synthesising-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF25">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02676">
        <property type="entry name" value="TYW3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111278">
        <property type="entry name" value="SSo0622-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="10">
        <location>
            <begin position="381"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="9">
        <location>
            <begin position="824"/>
            <end position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1079" mass="114383" checksum="C636601591661664" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUU0</accession>
    <name>C1MUU0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_58931</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059557.1">
        <property type="nucleotide sequence ID" value="XM_003059511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUU0"/>
    <dbReference type="STRING" id="564608.C1MUU0"/>
    <dbReference type="GeneID" id="9684692"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58931"/>
    <dbReference type="eggNOG" id="KOG0266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GPQRIFF"/>
    <dbReference type="OrthoDB" id="515012at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051242">
        <property type="entry name" value="WD-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324:SF4">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="383"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="608"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="929"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="937"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="954"/>
            <end position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="965" mass="105695" checksum="8582D9703E03CE7E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUW9</accession>
    <name>C1MUW9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_17639</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059574.1">
        <property type="nucleotide sequence ID" value="XM_003059528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUW9"/>
    <dbReference type="STRING" id="564608.C1MUW9"/>
    <dbReference type="GeneID" id="9684704"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17639"/>
    <dbReference type="eggNOG" id="KOG0244">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PIAWHAR"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 7 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="18"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="98"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="351" mass="37690" checksum="564F2BCBB9853DE5" modified="2009-05-26" version="1" fragment="single">MEALADALPTIEAEKELPVTVALMMRPLVGPELVDGCRECVFPNPEENSVTLVSEHKFTYDHVFHGPGPTEKALYEQCVEPLVRGLVCGYNATVLAYGQTGSGKTHCMGTSHEPGGATEGVIPRVMQTLFRTIADEPPEVSVKLKVGFIEIHKEDIRDLLVTDLKNAEAVSLRENVGRGQNGGVSLVGAKEVEVSTAAEMAAALASGSAARATAATGMNHRSSRSHAIFTIHVERRGRDPADVTRAKMHLVDLAGSERAKRTKAEGQRLKEGIQINKGLLALGNVISALGDDKRRHAGGHVPYRDSKLTRLLQDSLGGNSRTVMVACISPADANLDETMSTLKYANRARNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUY5</accession>
    <name>C1MUY5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58981</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059580.1">
        <property type="nucleotide sequence ID" value="XM_003059534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUY5"/>
    <dbReference type="GeneID" id="9684714"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58981"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="197" mass="21406" checksum="4AF714586F170533" modified="2009-05-26" version="1">MPPSRPSTDATSGLVAYRAVMALIRPSGDGAAEDIDAEFEDLSAIARALNPAVSRDALGWGLEAWVAQWLPRVGGWEERDEELSPTVRKYAVHAEDVLRASSFERASDPRDRRALPFRAYGSWIGARTSGRDALVDAAARLAREAAREELHVANRGDLFRAPADGGRPDLTSINRVMLASALDPLAFTRRAGEVEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV12</accession>
    <name>C1MV12_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59015</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059286.1">
        <property type="nucleotide sequence ID" value="XM_003059240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV12"/>
    <dbReference type="STRING" id="564608.C1MV12"/>
    <dbReference type="GeneID" id="9684726"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59015"/>
    <dbReference type="eggNOG" id="ENOG502QTAE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PRWHSEL"/>
    <dbReference type="OrthoDB" id="1915931at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34553:SF4">
        <property type="entry name" value="G1_S-SPECIFIC CYCLIN-E PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34553">
        <property type="entry name" value="OS05G0597400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="632" mass="67447" checksum="23F1DE08B3F634B8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV19</accession>
    <name>C1MV19_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_59024</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in rRNA-processing and ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UTP23/FCF1 family. UTP23 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059290.1">
        <property type="nucleotide sequence ID" value="XM_003059244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV19"/>
    <dbReference type="STRING" id="564608.C1MV19"/>
    <dbReference type="GeneID" id="9685038"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59024"/>
    <dbReference type="eggNOG" id="KOG3164">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HTSGLQM"/>
    <dbReference type="OrthoDB" id="25675at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08553">
        <property type="entry name" value="PIN_Fcf1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057776">
        <property type="entry name" value="UTP23_sensor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24779">
        <property type="entry name" value="UTP23_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP23 sensor motif region" evidence="8">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="209"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="261" mass="28311" checksum="19552B11A3BA981F" modified="2009-05-26" version="1">MRVKRARKVRKYLRYYRTCHGFRAPYKARPPRVVLVDGNFLHAVSQMKLGHAKDVLAKYLGAPSKLFTTRCVAHELKSMGAEFKEASFAARRAEEVKGGPDPPTPAFDSVVAAVAGDNAERFIVCTQDEKLRRKLMSDSAHVPVVFCHTSGLQMEPPSDATGGGVASQARSIHWSPYDPVGVSERAGGLSEGERLALGQEEVVNAMGGVRTNVRYKKPKARGPNPLSVKKKSENKRSATREGGGGGGGEGDGGAKKKRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV91</accession>
    <name>C1MV91_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_69769</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059332.1">
        <property type="nucleotide sequence ID" value="XM_003059286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV91"/>
    <dbReference type="GeneID" id="9685068"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69769"/>
    <dbReference type="OrthoDB" id="10612474at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="222" mass="22345" checksum="134597F75E30BD65" modified="2009-05-26" version="1">MATTRVGVATALAAPRARTRSTRRALVVVASASSSSRERRRNKYLRCQLRPRASSASVRLAARATTDASPGASRGASSSSPSPSPAPPPPLARSMLHLAKRAALAVAVAVALLLGGASSALAGAPFHGVPVVSSASATTIATGTAVANLPIAIGDVGSMGGLTPDAWGLPYRGKSAAMGLFMASAGVVMRMLVNVVVIYAIYTYWMGDEDSPGRGGKGGFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWC2</accession>
    <name>C1MWC2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_59711</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060190.1">
        <property type="nucleotide sequence ID" value="XM_003060144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWC2"/>
    <dbReference type="STRING" id="564608.C1MWC2"/>
    <dbReference type="GeneID" id="9685338"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59711"/>
    <dbReference type="eggNOG" id="KOG1609">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GYQYNLE"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347">
        <property type="entry name" value="RING/FYVE/PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347:SF1">
        <property type="entry name" value="RING_FYVE_PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="340"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="80"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="29"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="427" mass="46798" checksum="DF4437E2082F05CB" modified="2009-05-26" version="1">MASVQCEARARDMAGFVADEAAAVRAAQQRARVEAFNRRQRRERGYDDGDGDDDGVRRRTRAASGEHDDETRSGDAASSREREEPPQCRICFAGAEDATRGRLFSPCLCRGSMSHVHVECLNAWRAMSSNASSSARCDACRYVYVLKRARWATRFADPRLATVASVACIALAVVVSGVIARIASARVVAPAFAAAAAALKRTGTGTRTSGVVATLERLGSPRPTHAWRPWYAANGGGFPAGWVEERAAAASTRRALERTSPAHLEFLFYRLAMWTPPWWNPGGAFLDAFTIPRWFLRRAWIADALDALVTGVVLVGVGGAAFDVVGRLRRNFRSELERLAFPLAAMFASHGSPILRVVAIAGLMYVYYITHEIVRSRARTVLTKYGEYISDVRPRGAAEIEAARRGADAAVVADARRRWGARYFEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX22</accession>
    <name>C1MX22_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_40879</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060615.1">
        <property type="nucleotide sequence ID" value="XM_003060569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX22"/>
    <dbReference type="STRING" id="564608.C1MX22"/>
    <dbReference type="GeneID" id="9685761"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40879"/>
    <dbReference type="eggNOG" id="KOG4412">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EEWDTIN"/>
    <dbReference type="OrthoDB" id="497215at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051637">
        <property type="entry name" value="Ank_repeat_dom-contain_49"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180:SF45">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE TANKYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005667200" evidence="4">
        <location>
            <begin position="22"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="52"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="190"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="255" mass="27167" checksum="FE68F1F7B83BC6D7" modified="2009-05-26" version="1">MRSRHLLVVLIVLISCSFARAGIAHAKARAGDVEYFHDAMELDEINEREEGTGQTPLMAASLAGMHLAVEKLLDLGADADIPEKDGYNPPHGVAFQGRPLAARALIARGIPVDVAHADGFTPLHRTVWGRSPSHLETAIVLMSDGGADVNRVDAAGYPVAHRAVGERKGRAWIDALLRHGADVAYQVEDTGDTLLHAAVMSQDVEVIEAVVEAGGDVLVKNKKGLTPRGLAKSLGLEAATNVLSRTKFARGKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXW0</accession>
    <name>C1MXW0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60308</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060459.1">
        <property type="nucleotide sequence ID" value="XM_003060413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXW0"/>
    <dbReference type="STRING" id="564608.C1MXW0"/>
    <dbReference type="GeneID" id="9686204"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60308"/>
    <dbReference type="eggNOG" id="ENOG502QTMH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NPGWANG"/>
    <dbReference type="OrthoDB" id="434723at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039491">
        <property type="entry name" value="REX1-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28309">
        <property type="entry name" value="REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28309:SF1">
        <property type="entry name" value="REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14966">
        <property type="entry name" value="DNA_repr_REX1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="250" mass="26858" checksum="A0DFDC803BE7D58A" modified="2009-05-26" version="1">MENRARPPLPPVAGTAVELVERFFATQERRAAIYARFRDDFASHLRGETTAGDYDARVRAITSDMAACSLEAIAIEEALKTKGRDAASASIRVAQMGEKTKLNMTCTLQVLRKAASEGRWSWQRERGAEEEVAAAAARVAVEALAMEEERARDAARARRGGGLRTALNPGWANGNFCAAHDAGGATAAAGAACSCFDSAEDGAGEPTREEYDGATAEATKALEEAVIGINEALQELKYELAEMREEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXY0</accession>
    <name>C1MXY0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_60328</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060469.1">
        <property type="nucleotide sequence ID" value="XM_003060423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXY0"/>
    <dbReference type="GeneID" id="9685907"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60328"/>
    <dbReference type="eggNOG" id="KOG1676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HESGAYV"/>
    <dbReference type="OrthoDB" id="5204190at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="168"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="257"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="356"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="428"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="18"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="499"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="552" mass="60353" checksum="BA7F47F811B69D79" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ75</accession>
    <name>C1MZ75_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Basal body protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">OFD1</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_60630</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061165.1">
        <property type="nucleotide sequence ID" value="XM_003061119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ75"/>
    <dbReference type="STRING" id="564608.C1MZ75"/>
    <dbReference type="GeneID" id="9686349"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60630"/>
    <dbReference type="eggNOG" id="ENOG502QQR5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IDEMHER"/>
    <dbReference type="OrthoDB" id="437790at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060287">
        <property type="term" value="P:epithelial cilium movement involved in determination of left/right asymmetry"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055289">
        <property type="entry name" value="OFD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39063:SF1">
        <property type="entry name" value="OFD1 CENTRIOLE AND CENTRIOLAR SATELLITE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39063">
        <property type="entry name" value="ORAL-FACIAL-DIGITAL SYNDROME 1 PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16045">
        <property type="entry name" value="LisH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="706"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="192"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="602"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="706"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="742"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="765" mass="85757" checksum="0A46B8B65DADEEBF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZC9</accession>
    <name>C1MZC9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_60686</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061191.1">
        <property type="nucleotide sequence ID" value="XM_003061145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZC9"/>
    <dbReference type="STRING" id="564608.C1MZC9"/>
    <dbReference type="GeneID" id="9686377"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60686"/>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AEPDCYI"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="10">
        <location>
            <begin position="51"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH54841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="349" mass="37060" checksum="AA1D355D24D32CA0" modified="2009-05-26" version="1">MASTCSFVGATAPMRARVTARRGRAPRASVAPRAETSAVTCAVTPATVQQRSGSATVKGTSRKQNEDRFASYANANAPEGTPYAIYGVYDGHGGFAVSEWLKTNLADIILKEWPRADFCLEALSQACVKADYELVQPPPGIMGAFGERGVGGSKCGSTAVVATLFQEGGSTKLCTANVGDARIILVRDGKPVQMSVDHIPDDEMERRRIDAGNPNLRKSLVTFTEGSWRVGGVLALSRAFGDSFLKESGRFEGFGERNADYGSGFGLNAEPDCYIEQLTDKDTWLMMSSDGLFENNARGGGGGFTNEEIADFLTAASPDATPESLAKELCSMAVSKGSTDDVTVTIMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1N030</accession>
    <name>C1N030_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Elongator complex protein 3</fullName>
            <ecNumber evidence="15">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MICPUCDRAFT_45784</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>uridine(34) in tRNA + acetyl-CoA + S-adenosyl-L-methionine + H2O = 5-(carboxymethyl)uridine(34) in tRNA + 5'-deoxyadenosine + L-methionine + CoA + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:61020"/>
            <dbReference type="Rhea" id="RHEA-COMP:10407"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74882"/>
            <dbReference type="EC" id="2.3.1.311"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:61021"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="15 16">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the ELP3 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="15"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061055.1">
        <property type="nucleotide sequence ID" value="XM_003061009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N030"/>
    <dbReference type="STRING" id="564608.C1N030"/>
    <dbReference type="GeneID" id="9686764"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45784"/>
    <dbReference type="eggNOG" id="KOG2535">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TFETRPD"/>
    <dbReference type="OrthoDB" id="10265243at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106261">
        <property type="term" value="F:tRNA uridine(34) acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000003">
        <property type="entry name" value="Elongator complex protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034687">
        <property type="entry name" value="ELP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056591">
        <property type="entry name" value="ELP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01211">
        <property type="entry name" value="ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23613">
        <property type="entry name" value="ELP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005669">
        <property type="entry name" value="Hist_AcTrfase_ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01086">
        <property type="entry name" value="elongater_protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00344">
        <property type="entry name" value="ELP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11 16" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15 16" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 15" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 15 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="57"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="17">
        <location>
            <begin position="371"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR005669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR005669-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH54705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="525" mass="59063" checksum="8F2226A24582191C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1N082</accession>
    <name>C1N082_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_63642</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH55001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061351.1">
        <property type="nucleotide sequence ID" value="XM_003061305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N082"/>
    <dbReference type="STRING" id="564608.C1N082"/>
    <dbReference type="GeneID" id="9686520"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63642"/>
    <dbReference type="eggNOG" id="KOG0297">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CHTTIER"/>
    <dbReference type="OrthoDB" id="1737200at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001293">
        <property type="entry name" value="Znf_TRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131">
        <property type="entry name" value="TNF RECEPTOR ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131:SF94">
        <property type="entry name" value="TNF RECEPTOR-ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02176">
        <property type="entry name" value="zf-TRAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50145">
        <property type="entry name" value="ZF_TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="36"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="TRAF-type" evidence="6">
        <location>
            <begin position="350"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TRAF-type" evidence="4">
        <location>
            <begin position="350"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="519" mass="56696" checksum="57330A348550BBA9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0B5</accession>
    <name>C1N0B5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_28511</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NFYC/HAP5 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061605.1">
        <property type="nucleotide sequence ID" value="XM_003061559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0B5"/>
    <dbReference type="STRING" id="564608.C1N0B5"/>
    <dbReference type="GeneID" id="9686805"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_28511"/>
    <dbReference type="eggNOG" id="KOG1657">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RAYQSGM"/>
    <dbReference type="OrthoDB" id="1272441at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22908">
        <property type="entry name" value="HFD_NFYC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000006">
        <property type="entry name" value="Nuclear transcription factor Y subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF8">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="8">
        <location>
            <begin position="38"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="140" mass="16507" checksum="3CEC0710742F1A9A" modified="2009-05-26" version="1" fragment="single">MRAQLQHQQLAAYQMQTHHVAQQHQLQLRTFWQGQMREIETGSDFKNHQLPLARIKKIMKSDEDVRMISSEAPVLFAKACEMFILELTLRSWIHSEENKRRTLQRNDIAAAITKTDIFDFLVDIVPRDDFKEEGMNVQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0U1</accession>
    <name>C1N0U1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_48253</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061696.1">
        <property type="nucleotide sequence ID" value="XM_003061650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0U1"/>
    <dbReference type="STRING" id="564608.C1N0U1"/>
    <dbReference type="GeneID" id="9686892"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48253"/>
    <dbReference type="OrthoDB" id="430207at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF17">
        <property type="entry name" value="PROTEIN MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="486"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH54326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="542" mass="57225" checksum="84F4457BB5A530FA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N124</accession>
    <name>C1N124_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51233</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061734.1">
        <property type="nucleotide sequence ID" value="XM_003061688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N124"/>
    <dbReference type="GeneID" id="9687173"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51233"/>
    <dbReference type="OrthoDB" id="10678269at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="10"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="113" mass="11958" checksum="1A1C75760222CC49" modified="2009-05-26" version="1">MPLREYLAKVREDDAASSSSSSSRSPPTPTPTPPPRLVFCHRSSTFASAVRLLSDARAHHAFVLRDCDGDAAVAASAVAARTVGGVDVAVDDLCGIITLTDVLRRICFEDACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1C3</accession>
    <name>C1N1C3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_20694</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061541.1">
        <property type="nucleotide sequence ID" value="XM_003061495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1C3"/>
    <dbReference type="STRING" id="564608.C1N1C3"/>
    <dbReference type="GeneID" id="9687228"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20694"/>
    <dbReference type="eggNOG" id="ENOG502QQ73">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FNIIFYP"/>
    <dbReference type="OrthoDB" id="44480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009707">
        <property type="term" value="C:chloroplast outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046481">
        <property type="term" value="F:digalactosyldiacylglycerol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019375">
        <property type="term" value="P:galactolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01635">
        <property type="entry name" value="Glycosyltransferase_GTB-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000067">
        <property type="entry name" value="Digalactosyldiacylglycerol synthase 1, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044525">
        <property type="entry name" value="DGDG1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46132">
        <property type="entry name" value="DIGALACTOSYLDIACYLGLYCEROL SYNTHASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46132:SF1">
        <property type="entry name" value="DIGALACTOSYLDIACYLGLYCEROL SYNTHASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13692">
        <property type="entry name" value="Glyco_trans_1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="492"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="529" mass="58158" checksum="814E69FB21A6C059" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1C7</accession>
    <name>C1N1C7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_20182</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061790.1">
        <property type="nucleotide sequence ID" value="XM_003061744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1C7"/>
    <dbReference type="GeneID" id="9686984"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20182"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="169" mass="17571" checksum="A3298BC800AE3F94" modified="2009-05-26" version="1">MAQLPSYEVDDGEDSMPGAPGEGPMTDSMQGPPVEVPTSDSMPGAPGEVPTMDSMHGPPVEVPTMDSMHGAPVEVPMMDSMPGAPVEVPTMDSMQGPPVEVPTMDSMQGAPGEGPMTDSMHGAPGEGPTMDSMNSGNPTKCVVPDWCSTYPPEMQKSKPECQCPDDSHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1E4</accession>
    <name>C1N1E4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_51370</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061549.1">
        <property type="nucleotide sequence ID" value="XM_003061503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1E4"/>
    <dbReference type="GeneID" id="9686989"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51370"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="125" mass="13318" checksum="DB000CD16FB72707" modified="2009-05-26" version="1">MREILEIVVETGSAPIDSGDGKKAAAGGGVSLHFHFEKDDDAKKENAASPTAAVLKRMMPAMPRRLFNRVQAACADVEAAMGVVAERRVNFADAGAERRRLRGSKDASLAVDACKACEALIDWCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1L5</accession>
    <name>C1N1L5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48330</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061844.1">
        <property type="nucleotide sequence ID" value="XM_003061798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1L5"/>
    <dbReference type="GeneID" id="9687283"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48330"/>
    <dbReference type="OrthoDB" id="10681709at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="119"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="446" mass="44978" checksum="58B68F3E78377B32" modified="2009-05-26" version="1">MGMGTGMGMGTGTGMGMGMGAGGYHRSPSTPYGGQGVYPYAAPGSGWDLNPPRGPGGPGGMSTPFDLEDAIAYARGGGGGGDRTGGGAGDYLMGALETALGAGAEAARGGVQSEERRRAQAVVRQVAEALEDREEMADELDEAIARADAAEARAAAAEAAAAAATKEARDSVKEQRAEEQEAVLSALGLAEERAVQMAAECETLREEKDAIASALEYVNEEMETMRAREEATMQEFYRKGFAAGQAQYEELVKTHASRGQLEALGLTPTAPASASASGGGATTPSSPMASLMPTPEPFGTPVLTGNGSMAGVTMTTGSPTLARINTHTRAAAAEAKEDETSTVATVPPTGSSPEERENGGGGGGGGEVLLEESREVGRASGGRGGYPVSSPKKKLAEDAEAAIETATLFETVSLEDETSTGAGGGGGTPRSGRGTPKSSLSRQAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1U8</accession>
    <name>C1N1U8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_41932</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061976.1">
        <property type="nucleotide sequence ID" value="XM_003061930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1U8"/>
    <dbReference type="STRING" id="564608.C1N1U8"/>
    <dbReference type="GeneID" id="9687620"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41932"/>
    <dbReference type="eggNOG" id="ENOG502SY88">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="498732at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="693" mass="73549" checksum="A0A6692E2EB08EB3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N305</accession>
    <name>C1N305_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_42080</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TMEM43 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062294.1">
        <property type="nucleotide sequence ID" value="XM_003062248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N305"/>
    <dbReference type="GeneID" id="9687967"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42080"/>
    <dbReference type="eggNOG" id="ENOG502QSR2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NMMALDE"/>
    <dbReference type="OrthoDB" id="410725at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012430">
        <property type="entry name" value="TMEM43_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13416">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13416:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07787">
        <property type="entry name" value="TMEM43"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="466"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="505"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="231"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH53113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="542" mass="56704" checksum="4B59DE6A75B61B21" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3R0</accession>
    <name>C1N3R0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_42245</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062418.1">
        <property type="nucleotide sequence ID" value="XM_003062372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3R0"/>
    <dbReference type="STRING" id="564608.C1N3R0"/>
    <dbReference type="GeneID" id="9687858"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42245"/>
    <dbReference type="eggNOG" id="KOG2929">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MDRLHGV"/>
    <dbReference type="OrthoDB" id="498687at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057460">
        <property type="entry name" value="CAF17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GCV_T_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602:SF0">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25455">
        <property type="entry name" value="Beta-barrel_CAF17_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="CAF17 C-terminal" evidence="5">
        <location>
            <begin position="262"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="171"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="363" mass="37238" checksum="2812DDC20175303E" modified="2009-05-26" version="1">MTGRLAVGAALASRRVLRIGGEDALSLLQRVVTNDVRPLASPGAAPVYAALQNAHGRLEHDVFLHREMMSAAGGVSGALLADLPSDGFDAALALLMKLRLRAAVTLDDVGDDHAVVVAAADDDGEEGGRGTSVLPARFQFLPVDPRWVGLGRRGVLPAAAVAALLGSASPCGRGGSGGSDGGDASTSTSESESRSIDPFDGGGDAAYRRHRYLRGVAEGTAELATRLPLECNLEGLHGVSFDKGCYIGQELTARTHFVGVVRKRLAPIAFRSAEDAAAALASGGTVHSSAAAGPSGSKRERGGVGKVVAVEGDVGLAMMRVAAIGSDARMWATVDGGGEVEIETPASAPSWWPKEWTDAAERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3S7</accession>
    <name>C1N3S7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52283</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062666.1">
        <property type="nucleotide sequence ID" value="XM_003062620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3S7"/>
    <dbReference type="GeneID" id="9687867"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52283"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="767"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="792"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="802" mass="81417" checksum="5155B4BE756E9BEE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3T2</accession>
    <name>C1N3T2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA exonuclease 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_5594</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062428.1">
        <property type="nucleotide sequence ID" value="XM_003062382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3T2"/>
    <dbReference type="STRING" id="564608.C1N3T2"/>
    <dbReference type="GeneID" id="9688110"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5594"/>
    <dbReference type="eggNOG" id="KOG2249">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NWPCALP"/>
    <dbReference type="OrthoDB" id="16516at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06144">
        <property type="entry name" value="REX4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000007">
        <property type="entry name" value="Interferon-stimulated exonuclease gene 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037431">
        <property type="entry name" value="REX4_DEDDh_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF45">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exonuclease" evidence="10">
        <location>
            <begin position="11"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="186" mass="20476" checksum="C7F9EA9FBD4FCF33" modified="2009-05-26" version="1" fragment="single">APTGRNTALTDVIALDCEMVGVGEDGRRSILARVSVVNEDGNVVLDTFVAPTEHVTDYRTAVSGVRAQDLRGAPPFKEIQRKMADILRGRILVGHALKNDLRALLLDHPRRATRDTATYRPLTRPLRSRERAQADGIARGRGSRSLKELCARELGLEIQAGEHSSVDDARAALLLYQKCAKAWERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3Z2</accession>
    <name>C1N3Z2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52349</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062701.1">
        <property type="nucleotide sequence ID" value="XM_003062655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3Z2"/>
    <dbReference type="STRING" id="564608.C1N3Z2"/>
    <dbReference type="GeneID" id="9688141"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52349"/>
    <dbReference type="OMA" id="SERRYDH"/>
    <dbReference type="OrthoDB" id="10618780at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="329" mass="37112" checksum="8F72C5E78C3D0167" modified="2009-05-26" version="1">MAVIAAVKRGMASVGELKDQCNAAIRRGADVNGIEERQRIPVGGVHGRDYIKLMRADVKAAMKETAIAKGEGALLPGFGDHLDAREKSIATGRAPPPRLRLEDAAGPAERTRRLGDRGEEPTLALPESERGRRRGGDGGGSSASDDDESSSSSSSSSSSGRRRRRRRRREKRKKGGESKRKKRKRDRDDEEEDDDEVEDDGKSREALEKELEDERERRRKLKRRIRDGKRRDEKERRKRRGGDAKKKRRKSSSKRSKKRRRSDSDSDSESDSDSSSSSSSSSSSSSSDKRYDAISGKRIKLRRKKTRADDRLDYDRAKTLRLLNRAYND</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3Z5</accession>
    <name>C1N3Z5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52353</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062458.1">
        <property type="nucleotide sequence ID" value="XM_003062412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3Z5"/>
    <dbReference type="STRING" id="564608.C1N3Z5"/>
    <dbReference type="GeneID" id="9688143"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52353"/>
    <dbReference type="eggNOG" id="KOG0908">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MVISVEQ"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044534">
        <property type="entry name" value="TTL1-4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46050">
        <property type="entry name" value="TPR REPEAT-CONTAINING THIOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46050:SF29">
        <property type="entry name" value="TPR REPEAT-CONTAINING THIOREDOXIN TTL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="239"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="376" mass="39018" checksum="FD113086A84D2FD2" modified="2009-05-26" version="1">MAEAAKERGNALYKAGKFEDAVKAYDESIAADPAIAAAHANRAAALTAMGRAKFNDATVACVEALCLDPSYGRAKSRLGALCVKLGDLEPAVAAAEARARSHPDHSPSSSLAKALRLLRDGRAAGNAAFKSGDVARALKTYSDAMLAAAAEAAGSDAAAAGAMDAEALCVAVPGAALLMCNRAACAASLGRHADALTDATAALRADPEYAKASLRAAHARKALGEHAAAAAIFAELRERLPGDASVADELNACRRAAGGDLAKLPTERAGVIEIESMERYRALIAKAPLCLIDFTAKWCGPCKQVAPHFAAMALANPTIHFLKVDVDERQDISAAENVRSMPTFKAYRYGAKVDEFSGADLGRLQGLVARYLPTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5C3</accession>
    <name>C1N5C3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic initiation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">EIF4G</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_42607</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4G family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062942.1">
        <property type="nucleotide sequence ID" value="XM_003062896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5C3"/>
    <dbReference type="STRING" id="564608.C1N5C3"/>
    <dbReference type="GeneID" id="9688587"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42607"/>
    <dbReference type="eggNOG" id="KOG0401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CRIQIPR"/>
    <dbReference type="OrthoDB" id="514777at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253:SF53">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR ISOFORM 4G-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="5">
        <location>
            <begin position="546"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="90"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="465"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="739" mass="77912" checksum="118A22D220F47C7E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5D1</accession>
    <name>C1N5D1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Central pair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PF6</name>
        <name evidence="3" type="ORF">MICPUCDRAFT_42615</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062947.1">
        <property type="nucleotide sequence ID" value="XM_003062901.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N5D1"/>
    <dbReference type="GeneID" id="9688387"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42615"/>
    <dbReference type="OMA" id="ELTECPF"/>
    <dbReference type="OrthoDB" id="10257153at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990716">
        <property type="term" value="C:axonemal central apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904158">
        <property type="term" value="P:axonemal central apparatus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026173">
        <property type="entry name" value="SPAG17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21963">
        <property type="entry name" value="PF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21963:SF1">
        <property type="entry name" value="SPERM-ASSOCIATED ANTIGEN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14874">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="914"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1062"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1323"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1515"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1738"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2036"/>
            <end position="2105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="741"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1627"/>
            <end position="1672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="941"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="958"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1065"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1107"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1323"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1745"/>
            <end position="1754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1774"/>
            <end position="1792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2043"/>
            <end position="2054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="2060"/>
            <end position="2070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2082"/>
            <end position="2105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2105" mass="224793" checksum="A5C06FD84F9EFA8C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5I7</accession>
    <name>C1N5I7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52939</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063370.1">
        <property type="nucleotide sequence ID" value="XM_003063324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5I7"/>
    <dbReference type="GeneID" id="9688809"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52939"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="49" mass="5294" checksum="58A026DF6AF70A9B" modified="2009-05-26" version="1">MGLMSIVGKVVKFAEDHADYFHYAMIPAIIIVGMHTTPRPGLAALLTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5P2</accession>
    <name>C1N5P2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63730</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063397.1">
        <property type="nucleotide sequence ID" value="XM_003063351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5P2"/>
    <dbReference type="GeneID" id="9688836"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63730"/>
    <dbReference type="eggNOG" id="ENOG502S94I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="315" mass="33555" checksum="4F7A8813682C8E2F" modified="2009-05-26" version="1">MGYDVFLRYPRRAASSSRSGARRGGPGRQSRNRVSVRGMRTRTRRARRSPRAPPSLLALVVVVVVVLATAAPIARVSAEDASCPCLTAITWSLLGIDSGTNAACNRVDVAGEVQCYPATYGLTCAAHDSGLEPYCDAAVASPPAYCAEQWCYVDPALCRASSAGLRFGETQILQDASGLAYYSYATCGGDGSSWDTRELDNLKGKTLRAAVPILSYPPDQYVVDTATNAMVTTGYTTYGNLPSGADAKGIWVDLYERVALEAGFTIQWNTVSEGSLKAHSSKYTACVQDVADGLLGAFSSRRSPYDPVRAVHAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5Z5</accession>
    <name>C1N5Z5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_70907</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063448.1">
        <property type="nucleotide sequence ID" value="XM_003063402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5Z5"/>
    <dbReference type="STRING" id="564608.C1N5Z5"/>
    <dbReference type="GeneID" id="9688685"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70907"/>
    <dbReference type="eggNOG" id="KOG2755">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MCENLIL"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050260">
        <property type="entry name" value="FAD-bd_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43429">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43429:SF2">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="68"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="304"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH52584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="624" mass="66068" checksum="A32525B917A1927D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N640</accession>
    <name>C1N640_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42767</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063468.1">
        <property type="nucleotide sequence ID" value="XM_003063422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N640"/>
    <dbReference type="STRING" id="564608.C1N640"/>
    <dbReference type="ESTHER" id="micpc-c1n640">
        <property type="family name" value="Chlorophyllase_Plant"/>
    </dbReference>
    <dbReference type="GeneID" id="9688710"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42767"/>
    <dbReference type="eggNOG" id="ENOG502QRKW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RRLCSWG"/>
    <dbReference type="OrthoDB" id="2093222at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047746">
        <property type="term" value="F:chlorophyllase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015996">
        <property type="term" value="P:chlorophyll catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017395">
        <property type="entry name" value="Chlorophyllase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33428:SF14">
        <property type="entry name" value="CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33428">
        <property type="entry name" value="CHLOROPHYLLASE-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07224">
        <property type="entry name" value="Chlorophyllase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="488" mass="51747" checksum="0F8C85CCE87B1FAD" modified="2009-05-26" version="1">MATAATLRGPTWTPTSSSRRETTRRRGIDAARPRRRERRAADAPRASRDGDDAREISSSRDDGVPESPTRDVGRRDALSGASATFLGAAAGSFARRAVSAETSTSSSSGAAPSFVPMTPRSPSAVPNYALRGPFFVRRLPRLEHTCVTCFPKCVGDACLLGIDVHVPSAPPPLPDAMFPLDGVSLGGGDDDDDDDDDDDGVSAAAAGRMRGAPYPLAILTSGFLVDAEQYASYARRLCSWGYVVLSYNKRENVAGNALDDVVSAAMVRDLIQWAKSDVLLAPLLGSAEGDNIGVYLVGHSRGGKISVLEAIDDDRVKAVTLLDPVDNTVYAPLGEGFPSAVRAMRGKETGEGGGMLSRTRTPPLCVIGGLYGGECAPRGSNYVDFLREAPRNSWGVEVRGGHFQFLDSPSFVQRAVCEEGTAGDAQVREVSQALMVAHGESIFRGVNRERAFKRTLEALEAAWGGGAFSEALGQGRELPWVVLQDGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6H6</accession>
    <name>C1N6H6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53290</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063340.1">
        <property type="nucleotide sequence ID" value="XM_003063294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6H6"/>
    <dbReference type="STRING" id="564608.C1N6H6"/>
    <dbReference type="GeneID" id="9688780"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53290"/>
    <dbReference type="OrthoDB" id="10067079at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004860">
        <property type="term" value="F:protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009548">
        <property type="entry name" value="Prkrip1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507:SF0">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06658">
        <property type="entry name" value="DUF1168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="126" mass="13547" checksum="C3EC506FB8FBF18B" modified="2009-05-26" version="1">MERPSGEFHTYRMHRRREMLRLNAMHAEDKANAAEEAFRKRRAEVDAMEEAKLEKNRSKRAKKKAKVAAAREAKKAERAASKNGRGDGGGGDGGGGDGGDGKEKSGGSSPRDSDQGAGAADFETLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N770</accession>
    <name>C1N770_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53577</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063848.1">
        <property type="nucleotide sequence ID" value="XM_003063802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N770"/>
    <dbReference type="GeneID" id="9689125"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53577"/>
    <dbReference type="eggNOG" id="ENOG502QQ3J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CSMPDRV"/>
    <dbReference type="OrthoDB" id="497840at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="257"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="597" mass="65725" checksum="9306E5EF5B64F0B0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7C3</accession>
    <name>C1N7C3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53636</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063711.1">
        <property type="nucleotide sequence ID" value="XM_003063665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7C3"/>
    <dbReference type="GeneID" id="9689315"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53636"/>
    <dbReference type="OMA" id="WEFRTAD"/>
    <dbReference type="OrthoDB" id="498166at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="280" mass="30163" checksum="D9D61D7EE020DCC4" modified="2009-05-26" version="1">MAAMTSKLTTCVAPADSARRDGVVVVVVVVVAPRRVASSLVRDPSPPKIRSLLFLAADRRSIRPPPSVRPSVRRRRVVAAPKRATSSSSSSSSRRATVAVRASASPLKSAVASVSTASATAAIAFLASASPAMAASQTDETIAFLKAFWEFRTADPASFIAYTVLPIAVPYAVFKVLCDRKSERRRAELAAGGWDAFMAERGLPIDVLSLPQLNAFAAAAEKDLLDDEMVREFVRQKEISELWQKSTINVEDPRMENAKQRARAEKILALREEKANAGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7D6</accession>
    <name>C1N7D6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Flagellar inner arm dynein heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DHC6</name>
        <name evidence="18" type="ORF">MICPUCDRAFT_45980</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063717.1">
        <property type="nucleotide sequence ID" value="XM_003063671.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N7D6"/>
    <dbReference type="GeneID" id="9689158"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45980"/>
    <dbReference type="eggNOG" id="KOG3595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ECMREKK"/>
    <dbReference type="OrthoDB" id="5593012at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000002">
        <property type="entry name" value="Dynein axonemal heavy chain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.130:FF:000005">
        <property type="entry name" value="Dynein axonemal heavy chain 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000003">
        <property type="entry name" value="Dynein heavy chain 12, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000223">
        <property type="entry name" value="Dynein heavy chain 3, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000009">
        <property type="entry name" value="Dynein heavy chain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000044">
        <property type="entry name" value="Dynein heavy chain 5, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001328">
        <property type="entry name" value="Dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000005">
        <property type="entry name" value="Dynein, axonemal, heavy chain 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000006">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000362">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF1">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="11 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="9 18" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="17">
        <location>
            <begin position="2045"/>
            <end position="2080"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="481"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="2627"/>
            <end position="2678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEH52090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="3842" mass="431716" checksum="54A36F1844C47087" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7N1</accession>
    <name>C1N7N1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_53764</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064125.1">
        <property type="nucleotide sequence ID" value="XM_003064079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7N1"/>
    <dbReference type="GeneID" id="9689375"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53764"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="82" mass="8697" checksum="E4C7D6C47BE0C04F" modified="2009-05-26" version="1">MSAFLGSKIVAKATPVVAKRDVTVRAASASECVDPLGVTGAVVPSPRNFSRAVGSIDRSSDRSRLLRDWSPYDPVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7P9</accession>
    <name>C1N7P9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">mRNA cap guanine-N(7) methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">mRNA (guanine-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">mRNA cap methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_36785</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.56" evidence="10"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063946.1">
        <property type="nucleotide sequence ID" value="XM_003063900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7P9"/>
    <dbReference type="STRING" id="564608.C1N7P9"/>
    <dbReference type="GeneID" id="9689387"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36785"/>
    <dbReference type="eggNOG" id="KOG1975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LITGDCF"/>
    <dbReference type="OrthoDB" id="10248867at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA 5'-cap (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004971">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016899">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039753">
        <property type="entry name" value="RG7MT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189:SF2">
        <property type="entry name" value="MRNA CAP GUANINE-N7 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189">
        <property type="entry name" value="MRNA GUANINE-7- METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03291">
        <property type="entry name" value="mRNA_G-N7_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028762">
        <property type="entry name" value="ABD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51562">
        <property type="entry name" value="RNA_CAP0_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10 12" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MRNA cap 0 methyltransferase" evidence="13">
        <location>
            <begin position="40"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="49"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR028762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR028762-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR028762-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH51568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="383" mass="42335" checksum="402181B9BC182E70" modified="2009-05-26" version="1">MTEKRKRDDADAASDAEAARNVALHYSGRDNQSTAQRKQSPIYHLRCLNNWIKSTIISAYVRKGDRVLDFACGKGGDLPKFRKASIGSYAGIDIALESVRRDAVTRYNAAGYPFPASFIAGDGFAIDLTEHLPPASFDVISCQARSIHWSPYDRFAIHYSWSTEKRARTALNNVARLLRPGGHFVGTTVDANVLVRKLREADGLSFGNSIVRVTFDENKTFPSERGPFGLEYAFTLADAVTDCAECMVPRKRFVEIADECGLECVEWSNFHEYVRGKLRDDWSTATATATDASTEGKKTRPGEIAGGAATAHELWRQTMGGRSVHEVTLSEDEWEAAYLYATFAFKRKGTSAAAAAAVLRRPKPKHVWTRVEPEDVLVLEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7W4</accession>
    <name>C1N7W4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_43193</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064162.1">
        <property type="nucleotide sequence ID" value="XM_003064116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7W4"/>
    <dbReference type="STRING" id="564608.C1N7W4"/>
    <dbReference type="GeneID" id="9689421"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43193"/>
    <dbReference type="eggNOG" id="ENOG502RXH2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AANECMA"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964">
        <property type="entry name" value="ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964:SF113">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="1">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="UspA" evidence="1">
        <location>
            <begin position="189"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="343" mass="37492" checksum="460DCA02FE8DAA13" modified="2009-05-26" version="1">MPSSPCARSPSMEEMTFETPRTVLYAVGDKDAIDTKLSWRWARDNFFLPSDNIWLLKCKQKTSGWIPMDTVKTLSDASLAKDWLPSEIAHDVRGMEHRILLIETTHDPGDALVKFATMECPRDAIMLLGCRGRQGWRRMFLGSVTLYVTQHAPIAVLVVRSRKYRDIPDLTSDTVGAAYLGMTTPGKQRKVAIAIDGTSQSVALVRWAMSNALKPRDEVHLLHSAASENPEATLKATAAANECMAALSEFQRDDEGLCASVLLDMKGDTRDNIVDYVEDQGGAIDFLVMGTRGLTGNLKRAMLGSVSSYALAYCPSPVLTVPADIVAEAAKPTEEEEPASPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N840</accession>
    <name>C1N840_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43240</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064203.1">
        <property type="nucleotide sequence ID" value="XM_003064157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N840"/>
    <dbReference type="STRING" id="564608.C1N840"/>
    <dbReference type="GeneID" id="9689456"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43240"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARID" evidence="2">
        <location>
            <begin position="84"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="564" mass="58857" checksum="36C54A2EAA8FE15B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N876</accession>
    <name>C1N876_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53979</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064220.1">
        <property type="nucleotide sequence ID" value="XM_003064174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N876"/>
    <dbReference type="GeneID" id="9689475"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53979"/>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317">
        <property type="entry name" value="BLR8090 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37317:SF1">
        <property type="entry name" value="ZINC-RIBBON DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="2">
        <location>
            <begin position="38"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="2">
        <location>
            <begin position="106"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="19903" checksum="53B4ED533C052708" modified="2009-05-26" version="1">MVKKRGANQRTGGKPFIEWCAENGERGERLANEFREELPTELTKASHYKAKWKCLNCKHVWRAKVCNRTNSNRPSGCPQCANYAPASETNNFLAWCEKNGELGKKLSREYVDKDKPPTAVTKASRYKALWKCEECSHEWRARMTERTKSVRPTGCPACPPPGENLRKKRDRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8A5</accession>
    <name>C1N8A5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4a-hydroxytetrahydrobiopterin dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_49120</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="3"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064236.1">
        <property type="nucleotide sequence ID" value="XM_003064190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8A5"/>
    <dbReference type="STRING" id="564608.C1N8A5"/>
    <dbReference type="GeneID" id="9689488"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49120"/>
    <dbReference type="eggNOG" id="ENOG502QSK7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NGNTEHK"/>
    <dbReference type="OrthoDB" id="277398at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="entry name" value="Transcriptional coactivator/pterin dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599:SF8">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="PCD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="238" mass="25178" checksum="E9B90D575D1DE7E7" modified="2009-05-26" version="1">MFTATVATPAVAPLARAASASNARGANATATAPPRILRAAAALKSSSSAENRGASLATRGTRREMEELAGLGGDFGARDATAGELESNFNAKSIGEADTEHMLQIPRKVEEFTALHLRACVAVEAGEPPIEETQKLVYQKQVADWKIRIVDAHEVLRREFATGGDKAKAAEVVTRLEAVAEEEAQTIASFVEGPGVRIELHTAAVNGLHANDFVLAAKLDKVDLGDVTVKKKPNVFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8R8</accession>
    <name>C1N8R8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54216</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064495.1">
        <property type="nucleotide sequence ID" value="XM_003064449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8R8"/>
    <dbReference type="GeneID" id="9689936"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54216"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="102" mass="11401" checksum="3D4E1B14D9E8724B" modified="2009-05-26" version="1">MHAASWVADSDDDDGSEELEFASGVILVEVRARARRVYFRSVTSGLTRSHSPRVQDCKVGDWVEVNSGLAEPWRGQVRSTRRLNLHKMGLVSRSTDPTARAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8S1</accession>
    <name>C1N8S1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54219</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064323.1">
        <property type="nucleotide sequence ID" value="XM_003064277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8S1"/>
    <dbReference type="GeneID" id="9689938"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54219"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="418" mass="48676" checksum="F8F5D15134EE0511" modified="2009-05-26" version="1">MAKVVYVVEEERSWFSFFVSMLLNKWVLLALLIWYVYRTITVKIRSANLTRAQANSMKWGLIGLVLFALAERAEDFWEGLNPRIIRVWHILLQIGLVRRDSLSLKGEEHGLGYSFLASFCCCFAGRLVAGLEAWRIPDLVVDGTIFEFIGCWLIVSLLTKTKMWFIFGFPGLLLRKILYVGWGLNKIRQIERVWKPFAFTLLAFPATYLPWTTKIFYFTIRNIAGRTSRKLTDKIIAPKNKTKKEEKLDAKEEAERIAEEETSSQFSPPPSGKKKKKTVVNKKELLHELDDFFFVAPRTWQKQLAWNAVMLTIMSITQGDTMESIIEHTYCDDEDDFWCIPPAWNLHVHFPRFCFIVIALYIMHYYQQMAPPVAKFAKSDPQVVAQRKADKKERKKRDKEKVKQRKAAEKAAKKTKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8Y3</accession>
    <name>C1N8Y3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GCSH</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_37647</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="5">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GcvH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064360.1">
        <property type="nucleotide sequence ID" value="XM_003064314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8Y3"/>
    <dbReference type="STRING" id="564608.C1N8Y3"/>
    <dbReference type="GeneID" id="9689963"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37647"/>
    <dbReference type="eggNOG" id="KOG3373">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EHEWLSG"/>
    <dbReference type="OrthoDB" id="10264154at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002270">
        <property type="entry name" value="PRK01202.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="GLYCINE CLEAVAGE SYSTEM H PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715:SF3">
        <property type="entry name" value="GLYCINE CLEAVAGE SYSTEM H PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="51"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="4">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="154" mass="16496" checksum="963F12C8245E205B" modified="2009-05-26" version="1">MALRQFSRRVAAPMLNLRAAAPAMNARAMSTVIEGLKYMQSHEWAKVDGDVATIGITDHAQAELGDVVYVELPEVGSTVTHKETFGVVESVKAASDVYSPVTGEVIAINEDLADAPGKVNEGAFEDGWMMKVKMSNAGELDSLMDAAAYEKSCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N901</accession>
    <name>C1N901_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_43454</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064371.1">
        <property type="nucleotide sequence ID" value="XM_003064325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N901"/>
    <dbReference type="STRING" id="564608.C1N901"/>
    <dbReference type="GeneID" id="9689812"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43454"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="29"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="97"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="202" mass="21884" checksum="EA3A9266A05C39F3" modified="2009-05-26" version="1">MAKKLAGLFELTRASEAGFDPEKYGLDDDAALRIAAEFGRFDADGDGVINRDELERLLDEFGTARHASATRIIEEDSAETFEAEMFKPLIDYPSVYATPEGVKTAMEMIDGDGGGEISLEEFVQWYARECPLPPRGGKKKKKKKSTNNVVTIDIDDVDDDAAVDEDGDRRLLEAAAAADAELSAAGAVRSPHTGSHTTALAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9J5</accession>
    <name>C1N9J5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MICPUCDRAFT_43569</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasmic vesicle</location>
            <location evidence="13">Clathrin-coated vesicle membrane</location>
            <topology evidence="13">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Prevacuolar compartment membrane</location>
            <topology evidence="14">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064631.1">
        <property type="nucleotide sequence ID" value="XM_003064585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9J5"/>
    <dbReference type="STRING" id="564608.C1N9J5"/>
    <dbReference type="GeneID" id="9689904"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43569"/>
    <dbReference type="eggNOG" id="ENOG502QSX2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CQCAECK"/>
    <dbReference type="OrthoDB" id="10045365at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030665">
        <property type="term" value="C:clathrin-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00053">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000009">
        <property type="entry name" value="Low-density lipoprotein receptor isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026823">
        <property type="entry name" value="cEGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056858">
        <property type="entry name" value="VSR_TRX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22702">
        <property type="entry name" value="PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22702:SF1">
        <property type="entry name" value="PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12662">
        <property type="entry name" value="cEGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14670">
        <property type="entry name" value="FXa_inhibition"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25011">
        <property type="entry name" value="VSR_TRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 15" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="646"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="18">
        <location>
            <begin position="493"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH51536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="789" mass="83418" checksum="674E2DE56601B0CD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9L5</accession>
    <name>C1N9L5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_43381</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064305.1">
        <property type="nucleotide sequence ID" value="XM_003064259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9L5"/>
    <dbReference type="GeneID" id="9689916"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43381"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="407" mass="46759" checksum="6397C80BEE488AFC" modified="2009-05-26" version="1">MDAMRARRDEVEATRAFAEHYFRRWDDARHESLATRALARASADVRAMSNALLLGGVRDVSRRDAALRAMWTRWIAYVSLRELVPRLCGDLVRHDCAIVAWKHWVYATEDALARSRVATEMGAKARERRARSEKRIDARGVNAARLRNLSAARRERQDEVWGFHMDARPPGGGWRKRREEAKRAKRAAGDDDDERERERDDDSDDDARVVMDFEAHSHTTRAWRAWKDAKKARLRDEDATAALLATAEAAREGMRARVEARAAARVEDKRRQLERVARKKSLERFASELKGRELELNAADGSRVTYVAAVKLQSAVRGWLERRRYEKKKSNPFERVAGLRELLDRGDRAFSAQERVLLKAKDDWAASERRLTRMMLTNDDAIAALRVATETLRRVLYTGSHTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAA6</accession>
    <name>C1NAA6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_66010</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064871.1">
        <property type="nucleotide sequence ID" value="XM_003064825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAA6"/>
    <dbReference type="GeneID" id="9690312"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66010"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH50851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="96" mass="9890" checksum="5389390665F2D8DE" modified="2009-05-26" version="1">MVTDGCDAGGLSSASSALSVNTYAYSLVCDWSTTCFSWTYQGSFSSTTGEADIFFLTGDACNQQLFTSLPTSKLASVTAGSSQTISGTESYSASTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRB0</accession>
    <name>C1KRB0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit beta''</fullName>
            <ecNumber evidence="8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PEP</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Plastid-encoded RNA polymerase subunit beta''</fullName>
            <shortName evidence="8">RNA polymerase subunit beta''</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpoC2</name>
        <name evidence="12" type="ORF">MicpuC_chl2</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="12"/>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 Zn(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Plastid</location>
            <location evidence="8">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="8"/>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRB0"/>
    <dbReference type="STRING" id="564608.C1KRB0"/>
    <dbReference type="OMA" id="IEGKSDW"/>
    <dbReference type="OrthoDB" id="498011at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02655">
        <property type="entry name" value="RNAP_beta'_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1790.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01324">
        <property type="entry name" value="RNApol_bact_RpoC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012756">
        <property type="entry name" value="DNA-dir_RpoC2_beta_pp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02388">
        <property type="entry name" value="rpoC2_cyan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF68">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="1 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="9">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="11">
        <location>
            <begin position="87"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="10">
        <location>
            <begin position="168"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="10">
        <location>
            <begin position="1095"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACO50742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1227" mass="136850" checksum="0D13E5FBC7106CCE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRC5</accession>
    <name>C1KRC5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL16c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl16</name>
        <name evidence="7" type="ORF">MicpuC_chl24</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="7"/>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4 6">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 6">Plastid</location>
            <location evidence="4 6">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRC5"/>
    <dbReference type="STRING" id="564608.C1KRC5"/>
    <dbReference type="OMA" id="KGAVEYW"/>
    <dbReference type="OrthoDB" id="34872at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_uL16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_uL16_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_uL16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220:SF13">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACO50757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="140" mass="15748" checksum="623B41628C61DB55" modified="2009-05-26" version="1">MLSPKRTKYRKPHRGRLTGKAMRGNKIAFGDFALQALEPGWITSRQIEAGRRAMSRYARRGGKLWIRVFPDKSITARAAETRMGAGKGAPDYWVAVVKPGKILYEMRGVSEAIARSSMRIAAYKMPVKTKFLIREGFTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGK8</accession>
    <name>C1MGK8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ult-like transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_46107</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054792.1">
        <property type="nucleotide sequence ID" value="XM_003054746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGK8"/>
    <dbReference type="STRING" id="564608.C1MGK8"/>
    <dbReference type="GeneID" id="9680653"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46107"/>
    <dbReference type="eggNOG" id="KOG1886">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PGHHMRG"/>
    <dbReference type="OrthoDB" id="515966at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072357">
        <property type="term" value="C:PTW/PP1 phosphatase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.390.10">
        <property type="entry name" value="SAND domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010919">
        <property type="entry name" value="SAND-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000770">
        <property type="entry name" value="SAND_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46557">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46557:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63763">
        <property type="entry name" value="SAND domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50864">
        <property type="entry name" value="SAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SAND" evidence="4">
        <location>
            <begin position="287"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="1041"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="385"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="611"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="697"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="757"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="870"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="956"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="629"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="707"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="781"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="792"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="874"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="892"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="914"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="958"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1017"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1070"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1091" mass="114196" checksum="AB5FEF3814A413B8" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGM4</accession>
    <name>C1MGM4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_45131</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DExH box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054801.1">
        <property type="nucleotide sequence ID" value="XM_003054755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGM4"/>
    <dbReference type="STRING" id="564608.C1MGM4"/>
    <dbReference type="GeneID" id="9680304"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45131"/>
    <dbReference type="eggNOG" id="KOG0920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PNTRMQL"/>
    <dbReference type="OrthoDB" id="5600252at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000526">
        <property type="entry name" value="DExH-box ATP-dependent RNA helicase DExH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000002">
        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059023">
        <property type="entry name" value="RNA_hel_CTD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF237">
        <property type="entry name" value="ATP-DEPENDENT DNA_RNA HELICASE DHX36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26026">
        <property type="entry name" value="RNA_hel_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="34"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="256"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="618"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="632"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00060772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH60053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="830" mass="89101" checksum="2B7140602FEFD7C1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGQ0</accession>
    <name>C1MGQ0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49895</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054816.1">
        <property type="nucleotide sequence ID" value="XM_003054770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGQ0"/>
    <dbReference type="GeneID" id="9680664"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49895"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="104" mass="10720" checksum="274466F6CC68306A" modified="2009-05-26" version="1">MRGCAAEEAMLATVDAKLAAELAASAASAAATPTHASIERAWAHIATTARTDGDGDRAGGDDGDGDDDDDELARSWSGMEENVDAERARHKQCLALVRAVPLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGX7</accession>
    <name>C1MGX7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate-binding module family 48 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_30666</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054854.1">
        <property type="nucleotide sequence ID" value="XM_003054808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGX7"/>
    <dbReference type="STRING" id="564608.C1MGX7"/>
    <dbReference type="GeneID" id="9680297"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30666"/>
    <dbReference type="eggNOG" id="KOG1616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AMYDEMG"/>
    <dbReference type="OrthoDB" id="531008at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006828">
        <property type="entry name" value="ASC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037256">
        <property type="entry name" value="ASC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043554">
        <property type="entry name" value="KINB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46316">
        <property type="entry name" value="SNF1-RELATED PROTEIN KINASE REGULATORY SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46316:SF2">
        <property type="entry name" value="SNF1-RELATED PROTEIN KINASE REGULATORY SUBUNIT BETA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04739">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01010">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160219">
        <property type="entry name" value="AMPKBI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Association with the SNF1 complex (ASC)" evidence="2">
        <location>
            <begin position="139"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="228" mass="25477" checksum="5FC3747538F1D35E" modified="2009-05-26" version="1">MDIPVQAPSTPLSYGPQIPMVPGASGRGIPDLPGGWSEPNTLVPVAINWNQGGTVVEVEGSFDNWQSRQALHRSGNREFAVVKMLPPGVYQYKFIVDGEWKYAPDQPAMYDEMGNVNNVLEVQEYVPEILDSLDSFLAPSSPPESYDCALFTQDDFAKEPPACPPHLHLTLLNMPQIPDAPNLLPRPQHVVLNHMYNDRTKQQRGQHVMGTTHRYRSKYVTVVFVKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHK2</accession>
    <name>C1MHK2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_30839</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPL family. K-HECT subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054968.1">
        <property type="nucleotide sequence ID" value="XM_003054922.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MHK2"/>
    <dbReference type="GeneID" id="9680692"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30839"/>
    <dbReference type="eggNOG" id="KOG0168">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0170">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AEPLSQF"/>
    <dbReference type="OrthoDB" id="497634at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057948">
        <property type="entry name" value="TPR_TRIP12_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25579">
        <property type="entry name" value="TPR_TRIP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="1222"/>
            <end position="1605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="735"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="821"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="746"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="821"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="847"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="862"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="907"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="1572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH60220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1605" mass="169118" checksum="9218A03B71FA2EA3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI71</accession>
    <name>C1MI71_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50460</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055618.1">
        <property type="nucleotide sequence ID" value="XM_003055572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI71"/>
    <dbReference type="GeneID" id="9680821"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50460"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="472"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="643"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="687"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="245"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="476"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="494"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="725" mass="76357" checksum="01AE9AB8DECADCEB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI87</accession>
    <name>C1MI87_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_50478</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055627.1">
        <property type="nucleotide sequence ID" value="XM_003055581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI87"/>
    <dbReference type="GeneID" id="9680897"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50478"/>
    <dbReference type="eggNOG" id="KOG0509">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FNRFDRG"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="10">
        <location>
            <begin position="475"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="733"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="772"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH60879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="985" mass="107937" checksum="5A8FB8FDDCCF53ED" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIK9</accession>
    <name>C1MIK9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_61652</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055685.1">
        <property type="nucleotide sequence ID" value="XM_003055639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIK9"/>
    <dbReference type="STRING" id="564608.C1MIK9"/>
    <dbReference type="GeneID" id="9680818"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61652"/>
    <dbReference type="eggNOG" id="KOG3009">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GVHREWT"/>
    <dbReference type="OrthoDB" id="198885at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="entry name" value="Indigoidine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01876">
        <property type="entry name" value="PsiMP_glycosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909:SF1">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="ZGC:136858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110581">
        <property type="entry name" value="Indigoidine synthase A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="394" mass="40517" checksum="1686C8E50AF605F3" modified="2009-05-26" version="1">MMSRRRPLASTPGDMERATRSSRRVASLAHHLSPPSPSSSSASLVRSPTAAASPSSNDAIATSSNDEDEDPDGVLARASPSSWAISTGGVVVSPEVAEALADGRAVVALESTIVSHGMPYPENLAMAREVEAIVRARGATPATIAIVEGVPRVGLPDADLAKLAELGPRAAKVSRRDIAACVAAKATGATTVSATMLFASRVGVSVFVTGGIGGVHRGGENSMDVSSDLTEIGRTPVAVICAGAKSVLDIPKTLEVLETHGAAVVGYGADDFPAFFTRNSGCRAPTRVDTPAEAAALILAGKRLGLGGTVFGVPIPEEDEAKGGKVEAAIGKALREAEAKNVRGRDVTPFLLRRVRELTKGASLESNIALVKNNARVGSEIALALTELEKQPNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIU1</accession>
    <name>C1MIU1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carbohydrate-binding module family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_50694</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055722.1">
        <property type="nucleotide sequence ID" value="XM_003055676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIU1"/>
    <dbReference type="STRING" id="564608.C1MIU1"/>
    <dbReference type="GeneID" id="9680903"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50694"/>
    <dbReference type="eggNOG" id="ENOG502RZ05">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GATCCAN"/>
    <dbReference type="OrthoDB" id="564617at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050994">
        <property type="entry name" value="At_inactive_RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48010">
        <property type="entry name" value="OS05G0588300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48010:SF58">
        <property type="entry name" value="RECEPTOR PROTEIN KINASE-LIKE PROTEIN ZAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910484" evidence="4">
        <location>
            <begin position="34"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="5">
        <location>
            <begin position="453"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="5">
        <location>
            <begin position="693"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="5">
        <location>
            <begin position="757"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="5">
        <location>
            <begin position="804"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="558"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="558"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="602"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="630"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="673"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="845" mass="88935" checksum="8CE7D3387B954063" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ10</accession>
    <name>C1MJ10_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50767</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055754.1">
        <property type="nucleotide sequence ID" value="XM_003055708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ10"/>
    <dbReference type="GeneID" id="9680895"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50767"/>
    <dbReference type="eggNOG" id="ENOG502QWAD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RWESAIE"/>
    <dbReference type="OrthoDB" id="275936at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038781">
        <property type="entry name" value="C365.16-ike"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37845">
        <property type="entry name" value="SEQUENCE ORPHAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37845:SF1">
        <property type="entry name" value="SEQUENCE ORPHAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH61006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="513" mass="52461" checksum="CB3FDDE804E9BBBB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ13</accession>
    <name>C1MJ13_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_9855</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055756.1">
        <property type="nucleotide sequence ID" value="XM_003055710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ13"/>
    <dbReference type="STRING" id="564608.C1MJ13"/>
    <dbReference type="GeneID" id="9680277"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9855"/>
    <dbReference type="eggNOG" id="KOG1677">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WEESGSC"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000001">
        <property type="entry name" value="zinc finger CCCH domain-containing protein 15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000002">
        <property type="entry name" value="Zinc finger protein 36, C3H1 type-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH61008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="63" mass="7456" checksum="E6428C720827DD4C" modified="2009-05-26" version="1" fragment="single">YKTELCRSWEETGACRYGVKCQFAHGRDELRPVLRHPKYKTEVCRTFAQNGTCPYGTRCRFIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJH5</accession>
    <name>C1MJH5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55827</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056622.1">
        <property type="nucleotide sequence ID" value="XM_003056576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJH5"/>
    <dbReference type="GeneID" id="9682063"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55827"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="108" mass="11599" checksum="C9AFC0CCED6A42EC" modified="2009-05-26" version="1">MEAINALYQVMFDEEKATLAAAAAAGTQAALASPELRTSYADALLIAEEDALTIRACEWLEDAAALFVSRGEIDAAAFARRRCPLASGVSESFLHTIRYAMSSNLITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJI2</accession>
    <name>C1MJI2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_55833</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056216.1">
        <property type="nucleotide sequence ID" value="XM_003056170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJI2"/>
    <dbReference type="GeneID" id="9682067"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55833"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="211" mass="23056" checksum="BE30D11FA546B8F8" modified="2009-05-26" version="1">MKQKKEAKLAKSAANQEERRARDEKFAAEQASKRRERDERVAKENAANAKKNAAIEKAAKAKALKEQKAKDAAKQAKRARKDALKKKMAPKPALKAKKVKVVALKPKPKPKAVVAKPPADPNPLLVKTPPKPPRLETKKRSSAADAATNAKSSKTTKSSKTTKSKNARRPSSAKKTTRGRTQKKSSPIGGFFTFSLLCLVYAAYLDSTKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJZ2</accession>
    <name>C1MJZ2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Copper transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_55157</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055903.1">
        <property type="nucleotide sequence ID" value="XM_003055857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJZ2"/>
    <dbReference type="GeneID" id="9681906"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55157"/>
    <dbReference type="eggNOG" id="ENOG502S3NF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TSMYMDG"/>
    <dbReference type="OrthoDB" id="497712at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40855:SF1">
        <property type="entry name" value="CLAVAMINATE SYNTHASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40855">
        <property type="entry name" value="DIOX_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002911955" evidence="9">
        <location>
            <begin position="31"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="221"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="311"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="672"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="730"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="750" mass="75864" checksum="CAD7BF2EDD08892D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJZ5</accession>
    <name>C1MJZ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55161</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056299.1">
        <property type="nucleotide sequence ID" value="XM_003056253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJZ5"/>
    <dbReference type="STRING" id="564608.C1MJZ5"/>
    <dbReference type="GeneID" id="9681451"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55161"/>
    <dbReference type="OrthoDB" id="385235at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035770">
        <property type="term" value="C:ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901259">
        <property type="term" value="P:chloroplast rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000963">
        <property type="term" value="P:mitochondrial RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044528">
        <property type="term" value="P:regulation of mitochondrial mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050870">
        <property type="entry name" value="FAST_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228">
        <property type="entry name" value="FAST LEU-RICH DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228:SF40">
        <property type="entry name" value="LD45607P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="720"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="744"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="744"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="769" mass="80966" checksum="534FE64D8F7E1814" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKJ5</accession>
    <name>C1MKJ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_64455</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056396.1">
        <property type="nucleotide sequence ID" value="XM_003056350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKJ5"/>
    <dbReference type="GeneID" id="9681704"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64455"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="72" mass="8775" checksum="5DD9CADCB3D36D2E" modified="2009-05-26" version="1">MTTTFIGFWFFTSDRITVQHVYVYSCTRVCSIVRRYCVDLSTKKYFRKYLRKYESTFESTRTVQRCTCTTYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML02</accession>
    <name>C1ML02_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_31655</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="2"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056474.1">
        <property type="nucleotide sequence ID" value="XM_003056428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML02"/>
    <dbReference type="STRING" id="564608.C1ML02"/>
    <dbReference type="GeneID" id="9681545"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31655"/>
    <dbReference type="eggNOG" id="KOG0434">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EIIVIHK"/>
    <dbReference type="OrthoDB" id="1706657at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00818">
        <property type="entry name" value="IleRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000004">
        <property type="entry name" value="Isoleucyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000133">
        <property type="entry name" value="Isoleucyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000023">
        <property type="entry name" value="Isoleucyl-tRNA synthetase,cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19302">
        <property type="entry name" value="DUF5915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="11">
        <location>
            <begin position="22"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="12">
        <location>
            <begin position="712"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH59850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1111" mass="126094" checksum="039210644B36840B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMG3</accession>
    <name>C1MMG3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_6869</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057400.1">
        <property type="nucleotide sequence ID" value="XM_003057354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMG3"/>
    <dbReference type="STRING" id="564608.C1MMG3"/>
    <dbReference type="GeneID" id="9682363"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6869"/>
    <dbReference type="eggNOG" id="ENOG502QVX3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AWYGSEF"/>
    <dbReference type="OrthoDB" id="495408at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34123">
        <property type="entry name" value="OS04G0578200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34123:SF1">
        <property type="entry name" value="OS04G0578200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10184">
        <property type="entry name" value="DUF2358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="186" mass="19875" checksum="3238524E18131879" modified="2009-05-26" version="1" fragment="single">SDGNEDVGAGLKAVWYGAEAMGKMVGAVKSKDESSATSSASASSASAASSAATVDRERAIALLREDYDSSYFVSGVGELAAYAPDCEFSDPFVAFKGVDRFKQNVGNLGGMMRDVDLKITGWEESESDLVTSWRFSCVLDLPWKPKLAAAGGTTHVFDPDTGKVVKHIERWDVEPKKVVKQLLSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNW1</accession>
    <name>C1MNW1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_44039</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057180.1">
        <property type="nucleotide sequence ID" value="XM_003057134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNW1"/>
    <dbReference type="STRING" id="564608.C1MNW1"/>
    <dbReference type="GeneID" id="9682164"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44039"/>
    <dbReference type="eggNOG" id="KOG1343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CTSPAMG"/>
    <dbReference type="OrthoDB" id="424012at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09992">
        <property type="entry name" value="HDAC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF11">
        <property type="entry name" value="HISTONE DEACETYLASE 14, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="359" mass="37355" checksum="AA7E936203C4EC31" modified="2009-05-26" version="1">MDHERVGHPECNARVPAILAALDAARITARDRPGELVLLEDFAPATAEQIMEVHTKNFVQGLDILAKTRAPCDVDTAPTYVTPGSYDAAMRGCGAAIALVDAVVASAKARAGEEGGPENGGLAATGFGLCRPPGHHATPRAAMGFCLFGTVSAAARHAQRAHGLQRVLIFDFDVHHGNGTNDIFRDDPDVLFVSTHEDGSYPGTGKLSDVGDGDGAGASINIPLPPGSGDAAALAAFDEIVAPAALRFKPDIVLVSAGYDAHWRDALAGLNFRTGTYHRLSTRIKALANELCGGKCVFLLEGGYDLVGLSEGVVDSFRGLLGDASGEPGGRAEAVPGLGDEPEDKVRAVLREAKALHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNY2</accession>
    <name>C1MNY2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_56074</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056724.1">
        <property type="nucleotide sequence ID" value="XM_003056678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNY2"/>
    <dbReference type="GeneID" id="9682073"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56074"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="328" mass="35085" checksum="1279AFC7F2AB53D3" modified="2009-05-26" version="1">MLLHTKHASLPTSFADAFNAHCAPETIWPLEPIPAVAAKMKKRLKTHAADFRDGKSLPKHVEAATKASYGLDAVVNLMGVGAAATPLRPTTSLTHCSGFDFDEIFHPTVRAPFLIVRECLTRLLQSDGPRAVLSFCPPPRAGSGDNLGAYGLARAVHGMHLVGTAAEYATADALYVYAMWAEGAEKPSEALSDAIATAAGRVVDAGGAASARPPDSGTFWRVRDVAGVDDVENVGGVDDDEVVDDVEYTPRSWKFPDCAERFQKLVKLFGGSTSGFYGHEIPMPPPMDDAHAATATSVLEGTGKQFKTDPKEVQRAFEKRFNITGAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNY7</accession>
    <name>C1MNY7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56079</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057193.1">
        <property type="nucleotide sequence ID" value="XM_003057147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNY7"/>
    <dbReference type="STRING" id="564608.C1MNY7"/>
    <dbReference type="ESTHER" id="micpc-c1mny7">
        <property type="family name" value="Haloperoxidase"/>
    </dbReference>
    <dbReference type="GeneID" id="9682076"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56079"/>
    <dbReference type="eggNOG" id="ENOG502RZTA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAIIWSY"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="43"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="314" mass="34579" checksum="8455373D68068B68" modified="2009-05-26" version="1">MTSVTTKKGEVTLTLDEFRTKDDVRLVYEVGKGDPATTTSSSPVVLVHGWSGSRRYFDDSFAALLNAPSPPPRVVRYDLRGHGDSDKPEWGYHVARYAADLKELLEHLDLTDVTVVGTSMGCAIIWSYLELYGAERLKGAVCVDQAPLQNRAPDWNLGSKGCYDVASLTRLQELLKHDFEGFARGNAECCLSNEIDEEYEALLIAETLKASPTGLAALMADHTALDWRPTLRRTTLPMVVMAGAKSQIFPAEGVAHVGKLAANAVVVTYPTSDHWLYIEHWQKFADQVCDFAANGRLSRNFLGGMQQAVTVVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPE6</accession>
    <name>C1MPE6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56878</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057561.1">
        <property type="nucleotide sequence ID" value="XM_003057515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPE6"/>
    <dbReference type="GeneID" id="9683102"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56878"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="179" mass="19527" checksum="3E4990A3841CAF76" modified="2009-05-26" version="1">MPTLFETSFPKSVTSRPTGLTKTAVASVALALELATRAYRSSRPLLHAAISLPAIATALGAVTAIRSVIVAHAVMCSWLLTAFQVTLLAMHVCGVALERYDVRLGRRVAAPRFVSRFRTLPLFFFAAAVTAVSRVFSSPAQVNPAGRWILKLEAEAWEEISFAQDKSWSYLFAESPVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ11</accession>
    <name>C1MQ11_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_6062</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058044.1">
        <property type="nucleotide sequence ID" value="XM_003057998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ11"/>
    <dbReference type="GeneID" id="9683130"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6062"/>
    <dbReference type="eggNOG" id="KOG1971">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CLDGHHS"/>
    <dbReference type="OrthoDB" id="1736837at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24014">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24014:SF4">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25238">
        <property type="entry name" value="OGFOD2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="76"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="177" mass="19537" checksum="CD069D646B2A86E3" modified="2009-05-26" version="1" fragment="single">VFSFPLFSTEYAELLVAEIERFETSGLPVRRPNSMNRYGVVVNEIGLERMIDSLQTRVLSPISEALFPSQGGGCLDGHHSFIVRYKQGEDLGLDMHTDDSDVTFNVCLGKEGFTAAGLTFCGVLGGESHRKLSLVYKHVVGRCVVHLGAHRHGADDIGMGERLNLIVWNHSSLYRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQP8</accession>
    <name>C1MQP8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Folate-biopterin transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_57367</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057797.1">
        <property type="nucleotide sequence ID" value="XM_003057751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQP8"/>
    <dbReference type="STRING" id="564608.C1MQP8"/>
    <dbReference type="GeneID" id="9683235"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57367"/>
    <dbReference type="OMA" id="FYAICET"/>
    <dbReference type="OrthoDB" id="420638at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF0">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="200"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="469"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="476"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="517" mass="53166" checksum="CA046D0AB6513B24" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQZ2</accession>
    <name>C1MQZ2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_26472</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058215.1">
        <property type="nucleotide sequence ID" value="XM_003058169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQZ2"/>
    <dbReference type="GeneID" id="9683653"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26472"/>
    <dbReference type="eggNOG" id="KOG1444">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GWKDPTM"/>
    <dbReference type="OrthoDB" id="417037at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="3"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="292"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="331" mass="34108" checksum="8E16845818938201" modified="2009-05-26" version="1">MGFVNKAVLTVYGMRESNFLLLAQMCLTVLVLGALRAANQVSFPRINVATAKKLAPVAILYNANVAFALASLSKVSVPTYNTLKRLTPAVVLLANKTLRPQKPDPSRGVVGSISLVVLGCIVAGAGDLAFDLAGYLSGVASCLLQATYLIVVEITGAERGVGSAELLAYNALLSTPIVFALTSATGELASAVTRLGTLSEGAGFVTCFVGALSMGMLLNYSQFLCTMKNSALTTTVVGVLKGVASTALGFVLLGGVKFSLWHVVGITLNSVGGVMYSYVTFHERRRARAKLKESRSDVFERDGGGGGGGGGGLSAAERGGGHRSPRGVGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR22</accession>
    <name>C1MR22_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_47127</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057853.1">
        <property type="nucleotide sequence ID" value="XM_003057807.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MR22"/>
    <dbReference type="GeneID" id="9683669"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47127"/>
    <dbReference type="eggNOG" id="KOG0973">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1741719at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055410">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011494">
        <property type="entry name" value="HIRA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046468">
        <property type="entry name" value="Spt20-like_SEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24105">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07569">
        <property type="entry name" value="Hira"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12090">
        <property type="entry name" value="Spt20_SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="11"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="CAF1B/HIR1 beta-propeller" evidence="13">
        <location>
            <begin position="15"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="124"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HIRA-like C-terminal" evidence="11">
        <location>
            <begin position="680"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="domain" description="Spt20-like SEP" evidence="12">
        <location>
            <begin position="1126"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="402"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="892"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="998"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1273"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1405"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1634"/>
            <end position="1658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1672"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1738"/>
            <end position="1784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="402"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="505"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1013"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="1279"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1746"/>
            <end position="1757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF24105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH57804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1784" mass="186610" checksum="0D5C2CB003D61136" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR65</accession>
    <name>C1MR65_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_67594</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057877.1">
        <property type="nucleotide sequence ID" value="XM_003057831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR65"/>
    <dbReference type="GeneID" id="9683315"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67594"/>
    <dbReference type="OMA" id="SSMEVGW"/>
    <dbReference type="OrthoDB" id="410807at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="108" mass="11659" checksum="90C3160C56F186AA" modified="2009-05-26" version="1">MGSGSRYPPVRPQYDLVTHARLPQYKYSPDAPEKLAGGGQTIVPLADSGIKALGGCPSVALPEGKTTNSGTVIRTYKHLNIRSKLEPHERFSKPVTSSMEVGWGITPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRL1</accession>
    <name>C1MRL1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68226</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058527.1">
        <property type="nucleotide sequence ID" value="XM_003058481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRL1"/>
    <dbReference type="GeneID" id="9683966"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68226"/>
    <dbReference type="OrthoDB" id="10628577at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="293" mass="31263" checksum="CE7C9901E6B68A9C" modified="2009-05-26" version="1">MASMTTLSACAMARSAPASTRSVSRDRVASARVAPPALSRGYRFTMMEGRRKGVRRNAVEAAPADTDVDAESLKCDVENPCRDAVMAMVVTGERTLFPDASEDERARAAEATTTSATLAAFASSEAATRAILTGGEGDPEELAEPNTWKVVAPGFGGRLFFIGPECKLNPVSTFRIHEPRTSPNDDGAVTIQIEQLKGEINGSPPGVIKWINAAYTSERTVTTVVLDPAKGVARASVDVAVRVSVPRAFKFVPLHKIEKSMKKAFRKPTEKAMGEMCDAIGRAYVEWAAAGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRV9</accession>
    <name>C1MRV9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_6456</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058578.1">
        <property type="nucleotide sequence ID" value="XM_003058532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRV9"/>
    <dbReference type="STRING" id="564608.C1MRV9"/>
    <dbReference type="GeneID" id="9684380"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6456"/>
    <dbReference type="eggNOG" id="KOG3159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ICRMKEY"/>
    <dbReference type="OrthoDB" id="201621at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053264">
        <property type="entry name" value="Lipoate-ligase_2_inactive"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43506">
        <property type="entry name" value="BIOTIN/LIPOATE A/B PROTEIN LIGASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43506:SF1">
        <property type="entry name" value="BPL_LPL CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="27"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="212" mass="23526" checksum="515DF9C2D6F40C1B" modified="2009-05-26" version="1" fragment="single">VVKVIRTSGMCILRQLRLEEALLRVSSENYCVVNDGAKSPAVVLGISGKPHALLDVEAAQRDDLTVIKRFSGGGTVIVDGDTQFVTLVMNRDAHGSLPAPFPRPIMDWTGELYGARGGVFDGVRGFRLRENDYVVGEKKVGGNAQSISSGRWLHHTSFLFNFRDEMMRYLRHPEKTPEYRGGRSHADFLTPLSGLMPSRATMLDRIEPALRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS06</accession>
    <name>C1MS06_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58298</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058599.1">
        <property type="nucleotide sequence ID" value="XM_003058553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS06"/>
    <dbReference type="GeneID" id="9684406"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58298"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="168" mass="18324" checksum="A429869F1ED3DBB3" modified="2009-05-26" version="1">MAVAVRAPRSPEKAMALMAIFSTALIALLMWVSTTVSVHHEGQDPLTRGGRWANARHHRGRMRRAYERPGVAGEAAWEARDGGGGGGDGGEYDGGGGGGAGGGGARHRARDDDDDDDDRDLEHRRDREEVYDGRSHTQGDARRRGHRHGHHHHGHHDHARVFAGERTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSK0</accession>
    <name>C1MSK0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57721</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058336.1">
        <property type="nucleotide sequence ID" value="XM_003058290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSK0"/>
    <dbReference type="GeneID" id="9683806"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57721"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="149" mass="14613" checksum="D77E3774DD90882E" modified="2009-05-26" version="1">MTLSSELAPLKEEASGGGGGGDDAAGSDDALDGGGDRVGALGRPPRPLDHAMTVDSMGLSAMAASLPNGNGLVGSWGRERGKSPLGDDGGGGGGGGGGGVVARVSRDAKTLSGNPIMGFNIDPNARDLMKKKVDYSRRASIDVHPGSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSK3</accession>
    <name>C1MSK3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57724</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058338.1">
        <property type="nucleotide sequence ID" value="XM_003058292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSK3"/>
    <dbReference type="STRING" id="564608.C1MSK3"/>
    <dbReference type="GeneID" id="9684134"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57724"/>
    <dbReference type="eggNOG" id="ENOG502QU9I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007402">
        <property type="entry name" value="DUF455"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42782:SF4">
        <property type="entry name" value="DUF455 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42782">
        <property type="entry name" value="SI:CH73-314G15.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04305">
        <property type="entry name" value="DUF455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="505" mass="53344" checksum="42067F77942520BE" modified="2009-05-26" version="1">MASLARMACSLAAPTLARRARPAARAASLAVSTRRVAGGRRADDAVAVFAVAAARPRPRPRPRRATTAAGAAKTAAPIETIEAPPGGVWSGLDAWRASPIDRRYVWGERTAVDLGVVVPPGPWADPTRATASTIPTLPSTLAECADLILRTADPAIKAALSHRAYAAFVAAEDEDEDEDGGAARRRRMKIGRASPPDAPARPTRPTLVHPKDVPSPKTCELGMSAAMMHNIAHIELNAIDLAWDTVARFSALAAADDDDADEDDASTSSPRRFVVPMDFFRDFARVADDESRHLGWCLQRLSELGVAYGDIPAHNGSLAGRLAVVPCMQEARGLDAGPRLASKLQGRGDNRSAAMIARISDEELAHVAVGVAWFRELCGALRVDPGDAFRAHVGEHAPESLRGPFNHSARIAAGLEPNWYSVGPEHRMGIEFGTGTGTGTGTGFGDDAEGEGEEDGERELKKSAAALVARLKRMLELEGVAVAAGEATPPTAAEEEARGDDDRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSK8</accession>
    <name>C1MSK8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_57729</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. RRP8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058697.1">
        <property type="nucleotide sequence ID" value="XM_003058651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSK8"/>
    <dbReference type="STRING" id="564608.C1MSK8"/>
    <dbReference type="GeneID" id="9683815"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57729"/>
    <dbReference type="eggNOG" id="KOG3045">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PAWESYD"/>
    <dbReference type="OrthoDB" id="10258825at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2150:FF:000001">
        <property type="entry name" value="Ribosomal RNA-processing protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2150">
        <property type="entry name" value="Ribosomal RNA-processing protein 8, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007823">
        <property type="entry name" value="RRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042036">
        <property type="entry name" value="RRP8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05148">
        <property type="entry name" value="Methyltransf_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="266"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="781" mass="83754" checksum="4C285D1D26D2E277" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSL1</accession>
    <name>C1MSL1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_57732</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058342.1">
        <property type="nucleotide sequence ID" value="XM_003058296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSL1"/>
    <dbReference type="STRING" id="564608.C1MSL1"/>
    <dbReference type="GeneID" id="9684138"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57732"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FKMHRQP"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="525" mass="58890" checksum="F8DDBEE80D04BB82" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSM9</accession>
    <name>C1MSM9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PP1</name>
        <name evidence="12" type="ORF">MICPUCDRAFT_26683</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family. PP-1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058354.1">
        <property type="nucleotide sequence ID" value="XM_003058308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSM9"/>
    <dbReference type="STRING" id="564608.C1MSM9"/>
    <dbReference type="GeneID" id="9684144"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26683"/>
    <dbReference type="eggNOG" id="KOG0374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EEHEIRY"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000026">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="11">
        <location>
            <begin position="120"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH56809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="325" mass="36534" checksum="54A6B301C18FFA7B" modified="2009-05-26" version="1">MAGSGLDVDSVIERLLSVRGQPNNRTVQLAEGEIRALCATAREIFLGQPCLLELEAPLKICGDVHGQYSDLLRLFEYGGFPPEANYLFLGDYVDRGKQGLEVICLLLAYKVKYPENFFLLRGNHECNSISRIYGFYDECKRRYNIKLWRVFCDVFNCLPFAAIVDEKIFCIHGGPSPELKDLQQIVQIKRPTDIPDMGMLCDFLWSDPDADLQGWGENDRGVSYTYGTDVVADFLAKFDFDLVVRAHQVVENGYEFFGKRQLVTVFSAPNYCGEFDNAGAMMTVDENLMCSFQILKPAERKLMGGFGSMMGSRPSTPPRNKAGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT04</accession>
    <name>C1MT04_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68015</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058773.1">
        <property type="nucleotide sequence ID" value="XM_003058727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT04"/>
    <dbReference type="GeneID" id="9683857"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68015"/>
    <dbReference type="eggNOG" id="ENOG502QW8Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TCSPVYG"/>
    <dbReference type="OrthoDB" id="498425at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="537" mass="57971" checksum="04B7CC33EC919068" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT70</accession>
    <name>C1MT70_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mitogen-activated protein kinase kinase kinase</fullName>
            <ecNumber evidence="2">2.7.11.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_17505</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.25" evidence="2"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058436.1">
        <property type="nucleotide sequence ID" value="XM_003058390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT70"/>
    <dbReference type="STRING" id="564608.C1MT70"/>
    <dbReference type="GeneID" id="9684253"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17505"/>
    <dbReference type="eggNOG" id="KOG0198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YLTRECK"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06606">
        <property type="entry name" value="STKc_MAPKKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000387">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000615">
        <property type="entry name" value="TyrPK_CSF1-R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="25"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH56891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="289" mass="31839" checksum="D09CE5106320613F" modified="2009-05-26" version="1" fragment="single">MCSDDARTIRSGFYLAPAPTKPRRWTKGDALGAGSFGRVFLGLNSETGELFAVKEVAAAKRAECIEQLEQEVTLLSRLQHPNIVRYIGTERSAEFLYIFLEYVPGGSIASLLERFGRFEESVMSVYTRQILIGLDYLHAQRTVHRDIKGANILVEKSGRIKLADFGMAKTLVERIDDPAARARGGVKGSAYWMAPEVIRQKGHGSEADVWAVGCTVLEMATGKPPWSHCSGQVQVLYKIASTMELPEIPSFLSPDASEFVLLCLQRDPESRPAADRLLTHAFASSSTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU49</accession>
    <name>C1MU49_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aryl-alcohol dehydrogenase related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_18188</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059133.1">
        <property type="nucleotide sequence ID" value="XM_003059087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU49"/>
    <dbReference type="STRING" id="564608.C1MU49"/>
    <dbReference type="GeneID" id="9684499"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18188"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YQVHWPF"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19093">
        <property type="entry name" value="AKR_AtPLR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="73"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="388" mass="40750" checksum="5964989490D8322D" modified="2009-05-26" version="1">MRTTTTTPSALAPWARGAPIPRARAARAAVRARAPALLARASSESETTTTTSSASTTDRVTLGTSDLSVAATGVGAWAWGDRSGYWGDDWRGDRARNLRAYETLLAGGVDFIDTAEVYGFGKSEELIAEFARSTAGDDALVDPVFATKFAPLPLRWTASAVPDALEKSLARMGQKKIGLYMQHWPGFGIQDVANDAFLEGLCLCYERGLCDAVGVSNFNAARVATAAKKFASRGVPFASNQIQYSLLYRDPELKTGVVQACEDVGVTVVAYSPMAQGLLTGKYSGAGAAAVKGPRGAVFSDARRAAVGELVDLMKSIGKERGDKTPAQVAVNYCMTKGSVPIPGAKDAAQAASVVGCLGWRLSEGEVRELEKAAGKVPASPGAPFEAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUL3</accession>
    <name>C1MUL3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative GTP diphosphokinase RSH1, chloroplastic</fullName>
            <ecNumber evidence="2">2.7.6.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">RelA/SpoT homolog 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ppGpp synthetase RSH1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_27276</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RelA/SpoT family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.5" evidence="2"/>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059515.1">
        <property type="nucleotide sequence ID" value="XM_003059469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUL3"/>
    <dbReference type="STRING" id="564608.C1MUL3"/>
    <dbReference type="GeneID" id="9684955"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27276"/>
    <dbReference type="eggNOG" id="KOG1157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NIREWQE"/>
    <dbReference type="OrthoDB" id="496860at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000002">
        <property type="entry name" value="GTP pyrophosphokinase (RelA/SpoT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3210.10:FF:000001">
        <property type="entry name" value="GTP pyrophosphokinase RelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43061">
        <property type="entry name" value="GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43061:SF1">
        <property type="entry name" value="GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13328">
        <property type="entry name" value="HD_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="7">
        <location>
            <begin position="31"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="8">
        <location>
            <begin position="405"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00070102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00075768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00082153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="555" mass="60950" checksum="5307A5E794AD6C7B" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV11</accession>
    <name>C1MV11_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2 8">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_17826</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the phage and mitochondrial RNA polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 8"/>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059285.1">
        <property type="nucleotide sequence ID" value="XM_003059239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV11"/>
    <dbReference type="STRING" id="564608.C1MV11"/>
    <dbReference type="GeneID" id="9685035"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17826"/>
    <dbReference type="eggNOG" id="KOG1038">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ERDMICD"/>
    <dbReference type="OrthoDB" id="276422at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006390">
        <property type="term" value="P:mitochondrial transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000041">
        <property type="entry name" value="DNA-directed RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="entry name" value="DNA-directed RNA polymerase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046950">
        <property type="entry name" value="DNA-dir_Rpol_C_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00940">
        <property type="entry name" value="RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00900">
        <property type="entry name" value="RNA_POL_PHAGE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00489">
        <property type="entry name" value="RNA_POL_PHAGE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase N-terminal" evidence="10">
        <location>
            <begin position="1"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH56417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="838" mass="94067" checksum="45AA02835D5B0559" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV17</accession>
    <name>C1MV17_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59022</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059289.1">
        <property type="nucleotide sequence ID" value="XM_003059243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV17"/>
    <dbReference type="GeneID" id="9685037"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59022"/>
    <dbReference type="eggNOG" id="ENOG502SAQQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FTAMKMA"/>
    <dbReference type="OrthoDB" id="1902922at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050678">
        <property type="entry name" value="DNA_Partitioning_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13696:SF99">
        <property type="entry name" value="COBYRINIC ACID AC-DIAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13696">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="440" mass="47217" checksum="6E27F4F57DDE9D7C" modified="2009-05-26" version="1">MAPTHSTCFCNNRGGVGKTFMAFQTACEAARSRPDANVLVVDFSLYSDVTALLLGGSAREGFGAPMKGLQVTVENTTADTRAEGLIRDLELAIDADDDDARAGMKKKTKGSVFGAFFSKPSPAAAASSRREIDLQKYMIRPAAHNPAIPPNLYLIPSAGAVSWTDTQETNDDAADAAADDDEFVDAMDTTDRAPLWTRKGDAWHRAGARLARALDDLPPSFDAVFVDTDHLAACVLTKLALASCESVVVPLSFDDGDFNRLFQDVTGNALFTDVMIPMKAKGQLRARVKRMVFSKVGSNKNEAVTTAGGIESPFKPSKTVMDQMDAMAQQVWAACTHDERYKQLFAGAEELAPGQYGGGNIVGAFTAKFFTAMKMAPDLAANLSKMMGLPLCTMTSRTYHAPSGLEGQSGKPVLDSLKSETQRLVAGLLDDRYNLPLLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVA8</accession>
    <name>C1MVA8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_45626</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059634.1">
        <property type="nucleotide sequence ID" value="XM_003059588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVA8"/>
    <dbReference type="GeneID" id="9684783"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45626"/>
    <dbReference type="eggNOG" id="ENOG502SGVJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WFTGGWP"/>
    <dbReference type="OrthoDB" id="547828at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="213" mass="23131" checksum="6D60BF07E7640A1B" modified="2009-05-26" version="1">MFAVTTSVAAPVRPPRDRRPFASRARANPRPRKDGADGADVYIGKGRWVKDDPKKYAGRDDWFTGGWPGGEVGLKESFIQEPIEVDSGPTSNWAKLPEEFDGEDTVYVGKGKYLKADAKAFAGRDNLVTGGWAGGEVGLKLDKARKLKAGDYVAIKGSGGNFFQRLFSADDTRKTGTVKKVDIKASGKVTVSVAVLPFDNVEEFSDDQLEIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVL3</accession>
    <name>C1MVL3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_47693</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059772.1">
        <property type="nucleotide sequence ID" value="XM_003059726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVL3"/>
    <dbReference type="STRING" id="564608.C1MVL3"/>
    <dbReference type="GeneID" id="9685496"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47693"/>
    <dbReference type="eggNOG" id="KOG2023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AQEGAMS"/>
    <dbReference type="OrthoDB" id="951172at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="7">
        <location>
            <begin position="38"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH55724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="945" mass="101620" checksum="77C1483FE59E9C3B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVS0</accession>
    <name>C1MVS0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_18451</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059797.1">
        <property type="nucleotide sequence ID" value="XM_003059751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVS0"/>
    <dbReference type="GeneID" id="9685528"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18451"/>
    <dbReference type="eggNOG" id="KOG2632">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VWVELIL"/>
    <dbReference type="OrthoDB" id="10257275at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF1">
        <property type="entry name" value="RHOMBOID PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="9">
        <location>
            <begin position="55"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH55749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="153" mass="16766" checksum="7D18D128872F9F1F" modified="2009-05-26" version="1" fragment="single">MAIRLWNEIDRLPVKPPVTLGVMALSSALHFGILGDRTFSASDACLNPRAVIELGEWHRLVTAPLFYADEMHLVYNLSSMLWKGVQLETRMGSEAFAKLLVFLLVSVNAAACAVAWVTRAHFASVEEAYYRSCVTGSAGVLFALKSVIFSGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW41</accession>
    <name>C1MW41_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59617</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059857.1">
        <property type="nucleotide sequence ID" value="XM_003059811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW41"/>
    <dbReference type="STRING" id="564608.C1MW41"/>
    <dbReference type="GeneID" id="9685589"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59617"/>
    <dbReference type="eggNOG" id="KOG2275">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DWQSQCA"/>
    <dbReference type="OrthoDB" id="1883156at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="346" mass="36881" checksum="1F3679209473E9EF" modified="2009-05-26" version="1">MATTSLTAAPFARASVRAPRRSSRSASTTTTTTTRASGENSATIAGKNSPAFVDAVSGEWEGHSVYFDAAGTPIALPRNVVPPAFAEWGVELVDWQSQCAMRADDDAKEIYARELRFLPTVGCEADASTVESAIERRVAFDDVTPAPPGDDAPGGGNGVEFGSYSAGPGSLAARDGEETTIVMEHALAFTTGSGEDAKRTRLRLRQTISPVDGAIESIVGWKEYWYEPFNDAASLCSSCGGPNKWGETLATDPAATVSGPGWRGDDWRGLSDAAVMLREGVWSDRAVLPDGGGVVYQIGWHIPDRDAVYLPPCREVETHLVSEREYDGDGNFVGAKFMKLTRPAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW92</accession>
    <name>C1MW92_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_59673</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059884.1">
        <property type="nucleotide sequence ID" value="XM_003059838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW92"/>
    <dbReference type="GeneID" id="9685613"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59673"/>
    <dbReference type="OrthoDB" id="10265963at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="49" mass="5078" checksum="89FFCDAE8EEC74A0" modified="2009-05-26" version="1">MGAALAVGTALGSALGSSVAVDAPRGALELMFMGGMLFLSYRTFRTVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWY3</accession>
    <name>C1MWY3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_65335</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP17 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059711.1">
        <property type="nucleotide sequence ID" value="XM_003059665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWY3"/>
    <dbReference type="STRING" id="564608.C1MWY3"/>
    <dbReference type="GeneID" id="9685440"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65335"/>
    <dbReference type="eggNOG" id="ENOG502SDAS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PLAKMEC"/>
    <dbReference type="OrthoDB" id="551633at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019186">
        <property type="entry name" value="Nucleolar_protein_12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09805">
        <property type="entry name" value="Nop25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="148" mass="16078" checksum="A442A2F7BF08961F" modified="2009-05-26" version="1">MGKTTAAKKPFGKKAPFGTTKGAFGKEGKGGAKGKGKGGRPLAKMECGQEKTKRGGEAVFDDNVRRDWVTGYGKRKTQRRKYAVKQAEEKARKERLQERKERREEFRKTHGLTDDAGGGDGDSKPAGAVDTEVVEYDSGVTVIVEGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX52</accession>
    <name>C1MX52_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_68997</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060631.1">
        <property type="nucleotide sequence ID" value="XM_003060585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX52"/>
    <dbReference type="GeneID" id="9685775"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68997"/>
    <dbReference type="eggNOG" id="ENOG502SZRZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FTPYANS"/>
    <dbReference type="OrthoDB" id="496090at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="367" mass="40475" checksum="85F37A038B74694E" modified="2009-05-26" version="1">MHGFSKKQSRNRTERVLCWRSRRTSTRSVRVQLLYGFQSEARVPRPCFRRARKDSRPSHLRRGNLTRTKRSRSATRPSVPAHTPPSPPRTHAASRVSSRSPLITMSDSIDAMRKAQEDRFFKLEQEKYLLAYVKKLKASGRYDEIQVPTRAHSASALPQVLAHSVRLTALAEEQKHTRVVDRSFMTRQVLRGVTTGAPYLVDSLTMGSRVSLGKGKWSAGTVNSGVENTTIFSVHKAADLMSEAPKYLDGVESRAARHMVDTSFVEVAGKRIKLMPDPTPGRAMAWGGTLALWGTAAIVVGSCKVLGINSMVDLRRVMGETLTPLGSAIKSSVMPIKSFFNPDATSECSGLSTADSSFSKGIKKIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXA3</accession>
    <name>C1MXA3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_60082</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060360.1">
        <property type="nucleotide sequence ID" value="XM_003060314.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MXA3"/>
    <dbReference type="GeneID" id="9686096"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60082"/>
    <dbReference type="eggNOG" id="KOG1802">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF518">
        <property type="entry name" value="RNA HELICASE NONSENSE MRNA REDUCING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="728"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="993"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="842"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="964"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1284"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1311"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1334"/>
            <end position="1356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1566" mass="164403" checksum="27BD77A16A6AA929" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXD0</accession>
    <name>C1MXD0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60110</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060672.1">
        <property type="nucleotide sequence ID" value="XM_003060626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXD0"/>
    <dbReference type="GeneID" id="9685812"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60110"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="137" mass="14616" checksum="DFE5CF378E8B7E9C" modified="2009-05-26" version="1">MASASASASDATPPNDASSPDDRGAALEAWMRVGADDFDPRGVAVRRISDARGFGGVATRPIAAGDVLVVVPLTKMITSESVLRDARLGACAASLSDYQVRSIQKFFTHRSVSTFDRYPFQLTGELFLYGMALRGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXU3</accession>
    <name>C1MXU3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47951</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060755.1">
        <property type="nucleotide sequence ID" value="XM_003060709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXU3"/>
    <dbReference type="STRING" id="564608.C1MXU3"/>
    <dbReference type="GeneID" id="9686192"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47951"/>
    <dbReference type="eggNOG" id="KOG3881">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HRKFAAG"/>
    <dbReference type="OrthoDB" id="18388at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037379">
        <property type="entry name" value="WDR74/Nsa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038">
        <property type="entry name" value="NOP SEVEN ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038:SF4">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="322"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="458" mass="47963" checksum="4B96D1B11973B8BE" modified="2009-05-26" version="1">MSFSLAERARLAKKRDDTPVGAMERKMRLLAVDEIGVHRVLEAPSARHLEDLAVVSTWGESKRARRVVTLTAGVDATGGAAVDANAAGWFAMGRADDTVDVCDGVTGGVLGGGSVAVGALPVCATVFGPSSASASARLITVTENGDARVHAAACDVHAPADARIVGEWEEVVSNWKPCQSAIRACVSEDGATLATGGKGQGNNLKTHDIETQKVLFKAKAQPPNWLGYVAPPWVSAVRFLPGRGGGDGETILVGTGDHALRLYDLRQDSKRAVMDVQCGERENATTVMAVCGTRDGNTAFAADARGAVVAMDLRTQRSRGKLRGNSGSVRELALHPTLPLVATASLDRWIRVYDVDTCKCVGAGYTKQALCSVAWDVRGPAVAAAAAAAAERKKAKKKAAREGDDAGAEVAAGDGGGSDVAVKKKKKKKKRLCSDDDDVGVVKKKKKKKRAKEATEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXW4</accession>
    <name>C1MXW4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_60312</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060461.1">
        <property type="nucleotide sequence ID" value="XM_003060415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXW4"/>
    <dbReference type="GeneID" id="9686206"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60312"/>
    <dbReference type="eggNOG" id="KOG3567">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10044505at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016715">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.310">
        <property type="entry name" value="Copper type II, ascorbate-dependent monooxygenase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020611">
        <property type="entry name" value="Cu2_ascorb_mOase_CS-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000323">
        <property type="entry name" value="Cu2_ascorb_mOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036939">
        <property type="entry name" value="Cu2_ascorb_mOase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10680">
        <property type="entry name" value="PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01082">
        <property type="entry name" value="Cu2_monooxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00084">
        <property type="entry name" value="CU2_MONOOXYGENASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910554" evidence="7">
        <location>
            <begin position="44"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Copper type II ascorbate-dependent monooxygenase N-terminal" evidence="8">
        <location>
            <begin position="70"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="209" mass="22494" checksum="4F7D1A0C9F48E711" modified="2009-05-26" version="1">MPPPRERASPRRTPSRWRARRPRRLAIALVLCALAALSPRASAAVDDASADDDPQVRGSIAIELSTRDAVAARRDTYTYAHASMPKDGAHYIARFEPKADMAIVHHMLLFGCERGVASTLRTRSGGMFSAPGPAATSVEPRGAMCADSNVEPFIFGWGKNAPDLVLPKDVGFRVGAEGGGFESLVLEVHYLEAQARSPRTGPRTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY34</accession>
    <name>C1MY34_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_60385</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060496.1">
        <property type="nucleotide sequence ID" value="XM_003060450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY34"/>
    <dbReference type="GeneID" id="9686241"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60385"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF104">
        <property type="entry name" value="EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="SAP" evidence="6">
        <location>
            <begin position="129"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="5">
        <location>
            <begin position="529"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="619"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="506"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="638"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="661" mass="70513" checksum="73F38263D30A3BD1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY72</accession>
    <name>C1MY72_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_41115</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060517.1">
        <property type="nucleotide sequence ID" value="XM_003060471.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MY72"/>
    <dbReference type="GeneID" id="9686258"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41115"/>
    <dbReference type="eggNOG" id="KOG0008">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAYESYR"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040240">
        <property type="entry name" value="TAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022591">
        <property type="entry name" value="TAF1_HAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12157">
        <property type="entry name" value="DUF3591"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="7">
        <location>
            <begin position="1328"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="876"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="990"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1459"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1213"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="111"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="220"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="395"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="993"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1009"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1061"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1079"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1477"/>
            <end position="1491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH55286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1522" mass="162893" checksum="2680F602F337F370" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYA1</accession>
    <name>C1MYA1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59832</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060540.1">
        <property type="nucleotide sequence ID" value="XM_003060494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYA1"/>
    <dbReference type="GeneID" id="9685698"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59832"/>
    <dbReference type="eggNOG" id="ENOG502SG2U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="204" mass="21448" checksum="2BD3CD39C0544DC7" modified="2009-05-26" version="1">MASPRALGGAAVASPPLPSFASRRRRAARRARVASASSSSSSSSSSTLDVFVEIQMPDGSVPPRLTFALRPDLCPKSVENFATLLSGANAGVDPALTYRGCAFEPFGGKYSHVCKGRGKTIFGPGKFVEREAMSATRNGTPGAGGGTYYGERVDLDDDDDRVTVLAVPTSGPGFGGSRFAIMRRVRSMSHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYS7</accession>
    <name>C1MYS7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate-binding module family 20 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_41138</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060836.1">
        <property type="nucleotide sequence ID" value="XM_003060790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYS7"/>
    <dbReference type="STRING" id="564608.C1MYS7"/>
    <dbReference type="GeneID" id="9686530"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41138"/>
    <dbReference type="eggNOG" id="ENOG502QU99">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RERMEIM"/>
    <dbReference type="OrthoDB" id="498705at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05467">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15048">
        <property type="entry name" value="STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15048:SF0">
        <property type="entry name" value="STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM20" evidence="3">
        <location>
            <begin position="108"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="246"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="300" mass="33066" checksum="6BFA2523C1ABA2B9" modified="2009-05-26" version="1">MHDRDAPMKAPPPPARNPAYLLSNSNARPSVGGASSAGSKSQQGRSVAATTSPGVPGLGPDDWPCPVPVPGVPVDRSALGVEKRNAMNRANELMRLDPNDPKSLAALSMSDVDCAVQFKLPYDTAMGEELFIVGSHDRLGAWNQSRMLKMHWGDGGIWYADVELPAGGVFFYKYVLRDENGKFTWQDGANNLLVLPEEWDIPKDSRFVVDDKFGGTTRSSQNMLATKLISCEKEIVNLKLETIKAKEMTKASLQELMITREELESANEKLTMYERNVQTVITSMRQGQAKELNSNKHNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYV8</accession>
    <name>C1MYV8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LHCP2.1</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_70879</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061107.1">
        <property type="nucleotide sequence ID" value="XM_003061061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYV8"/>
    <dbReference type="STRING" id="564608.C1MYV8"/>
    <dbReference type="GeneID" id="9686290"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70879"/>
    <dbReference type="OMA" id="NASKHMR"/>
    <dbReference type="OrthoDB" id="494132at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="232" mass="24253" checksum="30BD3F19095B69D3" modified="2009-05-26" version="1">MACIASSFTGSVAALKATKVTQAKSVSTVVKADIYPEFGTYPGGGESPIIPFGSEKNAEREVIHGRWAMLGVTGAWAAENGTGIPWFTAGTLCTPDDCTAVADKFPGAVAPLAPEGSGYPSFWAVLAIEVVLVGLAEAYRTGLSDPVFDELTVGDVSPGGRFDPLGLAESGDLEELKIKELKHCRLSMFAWLGCIMQGLATQEGPIANWQAHVADPVHANVLTNAASGFGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ20</accession>
    <name>C1MZ20_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase kappa</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_3251</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060880.1">
        <property type="nucleotide sequence ID" value="XM_003060834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ20"/>
    <dbReference type="STRING" id="564608.C1MZ20"/>
    <dbReference type="GeneID" id="9686579"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3251"/>
    <dbReference type="eggNOG" id="KOG2094">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YFYWIAR"/>
    <dbReference type="OrthoDB" id="1747274at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03586">
        <property type="entry name" value="PolY_Pol_IV_kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.100:FF:000004">
        <property type="entry name" value="DNA polymerase IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.810:FF:000003">
        <property type="entry name" value="DNA polymerase kappa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000014">
        <property type="entry name" value="DNA polymerase kappa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.60:FF:000012">
        <property type="entry name" value="Putative DNA-directed polymerase kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.810">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050116">
        <property type="entry name" value="DNA_polymerase-Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022880">
        <property type="entry name" value="DNApol_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024728">
        <property type="entry name" value="PolY_HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002677">
        <property type="entry name" value="PRK02406.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076:SF33">
        <property type="entry name" value="DNA POLYMERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076">
        <property type="entry name" value="DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11798">
        <property type="entry name" value="IMS_HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="13">
        <location>
            <begin position="91"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH54530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="424" mass="45898" checksum="4379C16C2CA1390E" modified="2009-05-26" version="1" fragment="single">PTSAFTNAFTNAKAGMEGVDREMVKRVVHDMSVNSAHFATESRKEAAVEAKILAMKKRAASIRPSALATIKAAVDDRVARMEASRDLTKTWVHVDMDSFFASVHILERPELRDVPMAVGGMSMISTANYAARKFGVRSAMPGFIAKKLCPQLVFVDSDFAKYKHYASLTREVFKEYDPQFDAGSLDEAYLEISAYCAGKSMTPADVAEALRREVREKTKLTCSAGVAPTRRLAKVCSDANKPDGQMVIEPTRDAVAALLSSLPVRKIGGVGKVLDRTLAAFGIATCGDLLRERALVVALFSEVQSDFLLGVAIGVGGEARPARPPGWAPQRKSLSQERTFAPTADARALAAKIAALAEEVAAGLARENLLTRTVTLKMKRADFEVAQRQTSLPRPTNDAQTISDAALRLFRGEKNTHGSLRLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ58</accession>
    <name>C1MZ58_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Selenide, water dikinase</fullName>
            <ecNumber evidence="10">2.7.9.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SELD</name>
        <name evidence="10" type="ORF">MICPUCDRAFT_70214</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.9.3" evidence="10"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060899.1">
        <property type="nucleotide sequence ID" value="XM_003060853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ58"/>
    <dbReference type="STRING" id="564608.C1MZ58"/>
    <dbReference type="GeneID" id="9686598"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70214"/>
    <dbReference type="eggNOG" id="KOG3939">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HACSDLW"/>
    <dbReference type="OrthoDB" id="409395at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004756">
        <property type="term" value="F:selenide, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02195">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017584">
        <property type="entry name" value="Pyridine_nucleo_diS_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004536">
        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03169">
        <property type="entry name" value="Nterm_to_SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00476">
        <property type="entry name" value="selD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256:SF0">
        <property type="entry name" value="INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256">
        <property type="entry name" value="SELENIDE, WATER DIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0711">Selenium</keyword>
    <keyword evidence="1 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="9">
        <location>
            <begin position="15"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like N-terminal" evidence="7">
        <location>
            <begin position="459"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="8">
        <location>
            <begin position="580"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="771"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="787"/>
            <end position="799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="807" mass="84748" checksum="164AAC840D41BE04" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZE7</accession>
    <name>C1MZE7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_19844</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S9 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061202.1">
        <property type="nucleotide sequence ID" value="XM_003061156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZE7"/>
    <dbReference type="STRING" id="564608.C1MZE7"/>
    <dbReference type="GeneID" id="9686384"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19844"/>
    <dbReference type="eggNOG" id="KOG1463">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ESKIYHA"/>
    <dbReference type="OrthoDB" id="1418352at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000007">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040780">
        <property type="entry name" value="Rpn6_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040773">
        <property type="entry name" value="Rpn6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18503">
        <property type="entry name" value="RPN6_C_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18055">
        <property type="entry name" value="RPN6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="215"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="414" mass="45450" checksum="C7AAFC5750BACFFC" modified="2009-05-26" version="1">MAAAVELAGTNPAEAVKAYRAVVFSPNGADTESVKVKEQGIDALSKLLAKLQDAPALKLLLTELRPLFAVVPKAKTAKIVRNVIDVFATVPGSDDLQVELCKEQVAWAKEEKRTFLRHRVELRLSTLYLEKKAFQDALKLIGALAFEVKKLDDKLLLVDIHLLESRIHYALRNMPKAKAALTAARTNSNAIYVPPSVQCMIDSQSGILHAEEKDYKTAFSYFFEAFEQLNNLDDDAKAVNALKYMLMCKVMCGAADDVNALISSKGGLKHQGEALDAMKAVAQAYKDRSLKDMQRVLATYQAQLSEDPIIAAHLGALQDSLMEQNLMRVIEPFSQVEIAHVASLIELPLSVVESKLSQMILDGKFEGILDQGAGCLIVYDDGTPVTMYRATLDTIANMDKVVDTLLVKSQKIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZP3</accession>
    <name>C1MZP3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_3181</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061255.1">
        <property type="nucleotide sequence ID" value="XM_003061209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZP3"/>
    <dbReference type="STRING" id="564608.C1MZP3"/>
    <dbReference type="GeneID" id="9686694"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3181"/>
    <dbReference type="eggNOG" id="KOG0616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CETNETQ"/>
    <dbReference type="OrthoDB" id="377346at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="9">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="290" mass="32986" checksum="CAACC8CEDBAEA09C" modified="2009-05-26" version="1" fragment="single">LQKLVGKGGFSRVFHVKATARKADGAPIPGRDFVLKLIPIRKLVESGVEHTVRHERDLLSSVRHASVVRLHTAFKAMDHIYLIMDLVTGRDFYWIMQHYNLSDAGARFYIAQIVMVLEYLHKLSIAYRDVKPENFIVTTKDGYLRMIDFGLSKLLGPGERSYTFCGTPLYLAPEVWGSNGHNRSVDLWALGVLTYEMAFGKLPFEAKSESELKQKVVGDALKFPREIGSFGNDEIDPRLKSLIMGLLEKNSTRRLGMSKEGTKAVRSSAWFKDLDWHAIEKRKLEPPFYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZP6</accession>
    <name>C1MZP6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Set domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_19640</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060989.1">
        <property type="nucleotide sequence ID" value="XM_003060943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZP6"/>
    <dbReference type="STRING" id="564608.C1MZP6"/>
    <dbReference type="GeneID" id="9686428"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19640"/>
    <dbReference type="eggNOG" id="ENOG502QPN7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VVPWMMF"/>
    <dbReference type="OrthoDB" id="2019015at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF20">
        <property type="entry name" value="FLAVIN-CONTAINING AMINE OXIDASEDEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="520" mass="57829" checksum="E9B561DEE3A46B6E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N001</accession>
    <name>C1N001_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48156</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061309.1">
        <property type="nucleotide sequence ID" value="XM_003061263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N001"/>
    <dbReference type="GeneID" id="9686748"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48156"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="287" mass="31357" checksum="6CE90C0403416BCF" modified="2009-05-26" version="1">MKRSDAARLDAEAEAKTRVQRAELDAKTRVDAAEKTAAEKVAEAEARLTNAEVMKHLDAKVRASELEMRSRLAKIEAAASEKEKVAAAAKMVDAETAERASNWMTSAKAVEDMASTATRAIEGEMRLRDEVARLENELHDVRRELDHAVEEASMSAKTAADADAAAAAERERQRAAVAARLEEETTRADAAEADAKRWKLLADAREREVSKLASELETAATVAAAEAAAAADATDDVVGVYLTGIGDLRDELRAMKRRYAHDVDAAKVRSYLHWFPYNRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0L0</accession>
    <name>C1N0L0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_35238</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061407.1">
        <property type="nucleotide sequence ID" value="XM_003061361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0L0"/>
    <dbReference type="STRING" id="564608.C1N0L0"/>
    <dbReference type="GeneID" id="9687099"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35238"/>
    <dbReference type="eggNOG" id="ENOG502QV7B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YHKAHDF"/>
    <dbReference type="OrthoDB" id="2138282at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.10">
        <property type="entry name" value="PNP-oxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019595">
        <property type="entry name" value="DUF2470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037119">
        <property type="entry name" value="Haem_oxidase_HugZ-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13343">
        <property type="entry name" value="CREG1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13343:SF24">
        <property type="entry name" value="OS07G0573800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10615">
        <property type="entry name" value="DUF2470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CREG-like beta-barrel" evidence="3">
        <location>
            <begin position="45"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2470" evidence="2">
        <location>
            <begin position="211"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="339" mass="36325" checksum="5406C039852CA64F" modified="2009-05-26" version="1">MEADAKAREEAKAAQDAARAAWEANQPDPEMERFHEHQKTAVKLAHADECRTLIDQGRYGVLSTFDAKLGGEYPTGAVVGFASDDAGCPIFALSSMSGHTRDLKACGRCSLTVTQKGFQGSTEGFQSAADARVTLVGDMEAIEDDDGVAAARETYLAKHPDAFWVDFGDFSWHRMTATKGARLIGGFARAGGVDGDAYASATQDPVAQYSTPIATHMNVDHEKDLLDLVGHFVKLTVDKCRIESVDALGLNLLVMRRGEKFKVRLPFAEEARDRPSVKKVLVAMTKEASEAMKMKERWNAYGDIKDDPMGNKARAAAMAAQGEGGQQPGAGGGAAPGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0M6</accession>
    <name>C1N0M6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_48230</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061669.1">
        <property type="nucleotide sequence ID" value="XM_003061623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0M6"/>
    <dbReference type="GeneID" id="9687108"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48230"/>
    <dbReference type="eggNOG" id="KOG2130">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TNIVGHK"/>
    <dbReference type="OrthoDB" id="425950at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF6">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="4">
        <location>
            <begin position="135"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="341"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="370" mass="41425" checksum="7D2C4650E97C8285" modified="2009-05-26" version="1">MGAGGDAETPSSTSGTTAARRAVPTFPNAVACEKLSCDEISPEDFARLYVTRAMPCVLTDVASSWPCVGGDARWTLEHFKRAHGNLDVVVDDGTREKLRTSMAEYVDAFDAMADRAEAAAAEAAGSGDASDATPPYLRTWNFYDDVPGMLDGFPADSPYFRDYFKTLKEEWQPPFTWLFLGPRGARTRLHVDVWHTDAWLTMIEGRKKFIMYHPAHLKHVFDERTQTYVDLHAPDLEKFPDFARAVPVEFILEEGETVYIPRKFPHYAVALTHTVSLTVNFLASANRRNVVERCVAYANRRSACEFVLGRQLKASDNVMKFCVHGGDINKTMAASILGLSAEELEGKMREKKRELLRREAAEAEREEEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1K0</accession>
    <name>C1N1K0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flagellar outer dynein arm light chain 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ODA-LC6.1</name>
        <name evidence="2" type="ORF">MICPUCDRAFT_51433</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061571.1">
        <property type="nucleotide sequence ID" value="XM_003061525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1K0"/>
    <dbReference type="STRING" id="564608.C1N1K0"/>
    <dbReference type="GeneID" id="9687275"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51433"/>
    <dbReference type="eggNOG" id="KOG0907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WEEMLCL"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051766">
        <property type="entry name" value="TXND_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46135">
        <property type="entry name" value="NME/NM23 FAMILY MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46135:SF3">
        <property type="entry name" value="NME_NM23 FAMILY MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="8"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="117" mass="12987" checksum="55FE5787C6AB0BA7" modified="2009-05-26" version="1">MSFQTALTDDASWKLEIMETPGMFQIIDVHQSWTGPCKAIQSTFKKIFFEHGDKPIKFFTADASKIDAAKDYVGSCEPVFLFYKDGKKKEVRGVDAPTIVKMIYDGLGVDPNAAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1N283</accession>
    <name>C1N283_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_51884</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062246.1">
        <property type="nucleotide sequence ID" value="XM_003062200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N283"/>
    <dbReference type="STRING" id="564608.C1N283"/>
    <dbReference type="GeneID" id="9687685"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51884"/>
    <dbReference type="eggNOG" id="KOG0322">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="7668193at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="473" mass="48079" checksum="5A4F5DBA327840AF" modified="2009-05-26" version="1">MGNPAPDPVVLRGHGADVQCLAFARLDDARCLLSGRVLRPRASVSPPCKVLKDRRSPRERGRMETSLSDSNGDVVAWDLTTRRPAWRTRAHTPSSGTLAVALAPSSSSSSSSSETSSSAASVLSQGRDGTLKCWRAPPSFASASSASPSAATPADATWTASTGAYHFCKFAVAAASGGGGASSGAFYTLVPIRPQRPSFAAAAAAETSGVDVLCLPSASGGECGGPTLVTKLVMRGGAAAAEDGTSTVAHEKGAGAVMALSFVPRRGGDDSDDARPPLLLAAYEEGTVALWDPNRRAAANEENEDESPLWRDRVHEDAATCVAADADGAGFVTGGADGRVCAFSLAFDAAATTTTPTATVTMRHAHGPYTPSANVADRARWGGRAAGAGVSDVAIRGDGKLVAAACWDGRVRVYAYRGKTPKTLASLAFHSDVVTSVAFAGVGGGEDDGGGVLASASRDGCVALWPVFPTAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N287</accession>
    <name>C1N287_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCR4-NOT transcription complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_8014</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNOT11 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062248.1">
        <property type="nucleotide sequence ID" value="XM_003062202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N287"/>
    <dbReference type="STRING" id="564608.C1N287"/>
    <dbReference type="GeneID" id="9687488"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8014"/>
    <dbReference type="eggNOG" id="KOG4508">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TCISSCE"/>
    <dbReference type="OrthoDB" id="10265389at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019312">
        <property type="entry name" value="CNOT11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15975">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15975:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10155">
        <property type="entry name" value="CNOT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="177" mass="19367" checksum="D1F432751E769D44" modified="2009-05-26" version="1" fragment="single">HAGLSPADFPALVEHNPNVAHEFLVLAMSASAARSNTSRNAEEGGVTTTTTAPPPAASAFLDTLVQMEMSLHSMEVVNRLTTSPEIKARSIHWSPYDRLPSAFVHAYVANCVRSCAETSESGARTRLVRLACMFLQLLVRNKVVTAKDLVVETQAFCVEFMHVKEAATLFRLLKQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2A2</accession>
    <name>C1N2A2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51907</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062257.1">
        <property type="nucleotide sequence ID" value="XM_003062211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2A2"/>
    <dbReference type="GeneID" id="9687696"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51907"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="125" mass="13987" checksum="36EE4FCFC3D73848" modified="2009-05-26" version="1">MSSAFALSARAPLAARRRATLTRGLPRRARVRVGVAPRAQAAAGDKSKPQWSTDRQLAKDEDIDLKDGEKLMCVSPRVFFHRRARVLSAAKVLKERRSPRGRGRMGTSVTRATRARRNDESPRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2L8</accession>
    <name>C1N2L8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48370</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061898.1">
        <property type="nucleotide sequence ID" value="XM_003061852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2L8"/>
    <dbReference type="STRING" id="564608.C1N2L8"/>
    <dbReference type="GeneID" id="9687338"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48370"/>
    <dbReference type="eggNOG" id="KOG1810">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="73997at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056842">
        <property type="entry name" value="THADA-like_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051954">
        <property type="entry name" value="tRNA_methyltransferase_THADA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14387:SF0">
        <property type="entry name" value="DUF2428 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14387">
        <property type="entry name" value="THADA/DEATH RECEPTOR INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25151">
        <property type="entry name" value="TPR_Trm732_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA (32-2'-O)-methyltransferase regulator THADA-like C-terminal TPR repeats region" evidence="2">
        <location>
            <begin position="12"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="913" mass="94285" checksum="9A4610BE19AC520A" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2S1</accession>
    <name>C1N2S1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_51636</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061925.1">
        <property type="nucleotide sequence ID" value="XM_003061879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2S1"/>
    <dbReference type="GeneID" id="9687573"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51636"/>
    <dbReference type="OMA" id="AKRRCPW"/>
    <dbReference type="OrthoDB" id="498765at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="253"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="324" mass="34233" checksum="2DD95C406D929F83" modified="2009-05-26" version="1">MHSPHNDHSRLAKCPVCAKDVHKVLITEHVELCLSKSRARSPDDASASSRAPLADADARANANANGGGGGGSSRRGASAADRHLGAGWRKASGGPEASTAGGGAGDARRDLLFRWAGGGARHPAGGSVGAPRAKPRARPVGPLSAWVSSRAVEEEPEAKRPKRDDDDDDDGDGDGDGAGTRTGTGMAASAADERDDDERECDRENERECDDVDEDDDANETRAASAKETAEALGDAGLVPFNLRVMSGNHAECGICLQPFSSDDGGGDASARPTAVRHVFWPCQHVRQCGECAIRIWQTPKAKRRCPWCKSKIEIRPRAFKPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2V0</accession>
    <name>C1N2V0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_20969</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062146.1">
        <property type="nucleotide sequence ID" value="XM_003062100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2V0"/>
    <dbReference type="STRING" id="564608.C1N2V0"/>
    <dbReference type="GeneID" id="9687382"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20969"/>
    <dbReference type="eggNOG" id="KOG0676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YMPENML"/>
    <dbReference type="OrthoDB" id="74201at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="348" mass="36518" checksum="1E5F5013E8FB7288" modified="2009-05-26" version="1">MATAIGENIVVIDHDDDFIRAGYANPEYGPGVLAPASVRLASDATSDAIPPTRVIVDRAVTDWDALEAIYRHIFYKQCGWIEGEEGAALITEPLFTSKADRERLTQLMFESFNVAGLYIAEQPVAALYGVGKTSGVSVDVGFSTTDIAPVVDGVVVTAAATRCALGTVTTRDATRSLLGDAGAALSDDDVDAVRDATCHVSRSRDDALDASDSKTHVLPDGNVVTVDGAARRACVESLFAPDADKGGVSEASVLDAIFTHGGWAGGVGARSGVGLGRRITSDLHDLMPPTARPVEAGAPEYAHALTGQYASWFGGAILAKVVFPLNQYVTKVDYQENGPTVVHKNRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2V5</accession>
    <name>C1N2V5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_20971</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-13 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062148.1">
        <property type="nucleotide sequence ID" value="XM_003062102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2V5"/>
    <dbReference type="STRING" id="564608.C1N2V5"/>
    <dbReference type="GeneID" id="9687385"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20971"/>
    <dbReference type="eggNOG" id="KOG0246">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YIENHEF"/>
    <dbReference type="OrthoDB" id="497132at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903338">
        <property type="term" value="P:regulation of cell wall organization or biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000012">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF8">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 9 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="12">
        <location>
            <begin position="32"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="125"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH53860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="376" mass="40736" checksum="331C53D1C7B458ED" modified="2009-05-26" version="1" fragment="single">MVESERALLLESEEPPYPPLRRGEDADIPTCRVSVMVRKRPVSAKEFALKQCDVVTALRDSGHMVVHEPKVSVDMSRRVESSAFAFDGAFGEDSTNDEVYASAVAPLVRLCLEGQGAHATCFAYGQTGSGKTYTMKACYRAVAEELVEGAERCGLSLWVSFYDIYAGKCYDLLSSRKQLSALEDKRGRVRLVGLLETKVKSAREVMTAVERGMACRKTSRTDSNVNSSRSHSIFQVVLRPADAMDSKTPAMSRLSLVDLAGSERGADRGKAVDGKIRQEGAEINKSLLALKECIRALSSSGGGGGVNAVSEGVDPREDLGGDDRHVPFRGSQLTKVLRDAFVGAKSKTVLLAHVAPTSVAAEHTMNTLRYALRLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N350</accession>
    <name>C1N350_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_6886</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062548.1">
        <property type="nucleotide sequence ID" value="XM_003062502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N350"/>
    <dbReference type="GeneID" id="9687758"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6886"/>
    <dbReference type="eggNOG" id="ENOG502S02U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KRMFGHF"/>
    <dbReference type="OrthoDB" id="440619at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00093">
        <property type="entry name" value="pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF2">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="4">
        <location>
            <begin position="57"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="230" mass="25976" checksum="F9E9DF9B3B15AF78" modified="2009-05-26" version="1" fragment="single">RVNKCFKDFTSRRNADRLVASGAVTVNGAVVAAGAMVFPGDVVELRGERVRWETLNYVKYWKPRGVTCTTDARDRTNIVDAVNYPDARLFPVGRLDKDSTGLILLTSDGRLPNAALRSGRKRDKKYLVVVDAVVRPEDVRMLRDGVVISTPVQRDRVDRVLTARTLPCEIDVVGARTLEITLREGRNRQIRRMLDAVGYRVINLHRTEIMGIGLRGTREGRWVECDEEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1N362</accession>
    <name>C1N362_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42123</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062325.1">
        <property type="nucleotide sequence ID" value="XM_003062279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N362"/>
    <dbReference type="STRING" id="564608.C1N362"/>
    <dbReference type="GeneID" id="9687765"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42123"/>
    <dbReference type="eggNOG" id="ENOG502QUQV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4812at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009534">
        <property type="term" value="C:chloroplast thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045037">
        <property type="term" value="P:protein import into chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045038">
        <property type="term" value="P:protein import into chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017499">
        <property type="entry name" value="Thf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34793">
        <property type="entry name" value="PROTEIN THYLAKOID FORMATION 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34793:SF1">
        <property type="entry name" value="PROTEIN THYLAKOID FORMATION 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11264">
        <property type="entry name" value="ThylakoidFormat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="222" mass="24208" checksum="AC4FAD2036B703E3" modified="2009-05-26" version="1">MASIAAHASAVCRVTAPRTGARRASKARATRGVAVRAAVDLNEVTVADTKQKFLKSYPYPIPSIWSVALQELLVTQHFVRYSKKYSYSKLSSLGFVSVYDQLFEGFPSEEEKNTIFECFVKALEEDPATVRKDAAELASFAEGASGVDGVLASPIFAQMKSLVADGKFAYSRYDAIGLFRLLELAKATEPAALEKLAESSGLQARSIHWFPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3U6</accession>
    <name>C1N3U6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_52302</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062677.1">
        <property type="nucleotide sequence ID" value="XM_003062631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3U6"/>
    <dbReference type="STRING" id="564608.C1N3U6"/>
    <dbReference type="GeneID" id="9687875"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52302"/>
    <dbReference type="eggNOG" id="ENOG502RZSC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TMVAVRI"/>
    <dbReference type="OrthoDB" id="513226at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110102">
        <property type="term" value="P:ribulose bisphosphate carboxylase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.210">
        <property type="entry name" value="Chaperonin-like RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038052">
        <property type="entry name" value="Chaperonin_RbcX_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003435">
        <property type="entry name" value="Chaperonin_RcbX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791">
        <property type="entry name" value="CHAPERONIN-LIKE RBCX PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791:SF1">
        <property type="entry name" value="RUBISCO CHAPERONE RBCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02341">
        <property type="entry name" value="RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158615">
        <property type="entry name" value="RbcX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="37"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="227" mass="24317" checksum="F14C9173E5BA44B9" modified="2009-05-26" version="1">MFASIAINVVVPAASSRASARGATRARPVAPLASSLASKNPLSERTGASLGDRRAFARRRASSLRARAGDDREGSVGGGTGDNGRMHVPTDAFGGMSPEYKAASALKSLFTMVAVRIVMAQEAGYDNEGGAMTPTYKGLQDYLQENPLRDGNKWLEALMRHEDNNMRLTALRVLEVRKAYAEGQFDFKGMSSLAVEELTTENDKLMADYVKDSMSLPSTEGMGMDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3V1</accession>
    <name>C1N3V1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_42270</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062437.1">
        <property type="nucleotide sequence ID" value="XM_003062391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3V1"/>
    <dbReference type="STRING" id="564608.C1N3V1"/>
    <dbReference type="GeneID" id="9687877"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42270"/>
    <dbReference type="eggNOG" id="KOG0557">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VEIECWQ"/>
    <dbReference type="OrthoDB" id="537444at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF75">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT 5 OF PYRUVATE DEHYDROGENASE COMPLEX, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="20"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="168"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="115"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH53256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="463" mass="46441" checksum="BA28203DA5334AF7" modified="2009-05-26" version="1">MTAKKVVRAGSRSVVTRAEVKEIHMPALSSTMTEGKIVSWLKGEGDSISKGEAVVVVESDKADMDVETFYDGYLAYIAVEDGEMATVGAPIAYVAETEGEIDQAKAMAAAAGGGAAPAAAPAPAAPEPAPAAPPPPPPAPVAAAPAPAPAPAPAAAAPVAGRPDGRIIATPYAKKLAKKLKVDLATVAGSGLNGRITAGDVESKAGVPSSTAPKKAAATAPAAAAAPSAASAPPAPLPAPAGAQTPLSGMQKAVAKNMMPSLQVPVSRIAMSMCTDELDALYKKVKPKGVTMTALLAKAVGVALAQHPIMYASPVPAGDAVVYNDKVNIAVAVALESGLITPVLADTAGTDVYEIGRVWKDLVKKARGAGLSPADYAGGNFTISNLGMFGVDAFDAILPPGQGAILAVGAGKPTVVPVNGMIGIKTLMTVNLTADHRHINGDVAAEFLKTLKAVIEDPSELVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N415</accession>
    <name>C1N415_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52373</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062715.1">
        <property type="nucleotide sequence ID" value="XM_003062669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N415"/>
    <dbReference type="GeneID" id="9688155"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52373"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="236" mass="25222" checksum="4AB60733F51C0BBE" modified="2009-05-26" version="1">MERDGDDASSSDPDPREDDILFSALVGALSRGVDASKAREVVRQQSVPPPIGLGPSWAATAAALAEDETRRRRAREALTVRVALPPAEDEDEDDDDASTLSRSEASASSHHGNLASKLETLARRAFDGPRDRLGGKAERFADANGASLAAPQLVRASWDGARRARSKSVENARERVTNDDDPPLYNPSVAAKRPRAPGVAWGPPRAPPDAIRRSATKRVSLTCVLYTGPHTTAFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4X0</accession>
    <name>C1N4X0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42502</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH53008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063069.1">
        <property type="nucleotide sequence ID" value="XM_003063023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4X0"/>
    <dbReference type="GeneID" id="9688307"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42502"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="410" mass="42224" checksum="5EE75CFC2F5917A3" modified="2009-05-26" version="1">MAWQDSHGIAGLSSLGASPLATPRRPVGVDAVPATQEPSSTPANATSRMSFDSQGGGGKASSASRMSFDNDRDDGVSSPPFRSVPRSGGGGAGSRWSPYGFAEPAELGPGGASMSTRLKRPRSSSHLSDDDVQPTRLFGASPGTKRALSEMMAKDLQRLNVSPAAAAGAGERDLRVRERNSFDGGAAASASAWATTQPHAVTPRASWEGIDADASPWASSFGVVSPGAAAAADGRLTTWNDASPMSTEKDAFDDANDADAAPGSVVSVMSVDAFSPSPHSRLVLPESIARRRSALSQQLREASCLPEGLPPGTVGSSRGFFGGGGAESRDAAAAGAPAFLPPSPSGEVSPRSDLRKQAILKRVSLAAHAMPMMHATPRLMLPPAIGPPGREDDDDGDDENDVDENKRMIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5G4</accession>
    <name>C1N5G4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar radial spoke protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RSP2</name>
        <name evidence="1" type="ORF">MICPUCDRAFT_52908</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063154.1">
        <property type="nucleotide sequence ID" value="XM_003063108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5G4"/>
    <dbReference type="STRING" id="564608.C1N5G4"/>
    <dbReference type="GeneID" id="9688601"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52908"/>
    <dbReference type="OrthoDB" id="526070at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="213" mass="22269" checksum="73599C7C5B9CAAAD" modified="2009-05-26" version="1">MEGGMFHHVNNCAQNQNHATRVYDGQALRERHPDRSDPFPPGVVEDEISIAFGRRHVAKLVDVVSLPGSKLNGKERAKALRYLLGCLSNQESNAEAVVLNVAAPATALLGDGNPEVRRLACDVLSGCDALLRSGAIETIVASSLKDADAAARDAAAGVIASATRTRPGAEAALNAADGAVVPALRDMILGADSGAFSLHWSPYDPVRVVNAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5Q4</accession>
    <name>C1N5Q4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_22355</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063200.1">
        <property type="nucleotide sequence ID" value="XM_003063154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5Q4"/>
    <dbReference type="STRING" id="564608.C1N5Q4"/>
    <dbReference type="GeneID" id="9688841"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22355"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HVEEWNP"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="29"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="398"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="450"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="676" mass="72789" checksum="3729AAAD4F5E4723" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1N646</accession>
    <name>C1N646_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_36377</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063472.1">
        <property type="nucleotide sequence ID" value="XM_003063426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N646"/>
    <dbReference type="STRING" id="564608.C1N646"/>
    <dbReference type="GeneID" id="9688911"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36377"/>
    <dbReference type="eggNOG" id="KOG0903">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05168">
        <property type="entry name" value="PI4Kc_III_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000016">
        <property type="entry name" value="PIK1p Phosphatidylinositol 4-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057754">
        <property type="entry name" value="PI4-kinase_beta/PIK1_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="6">
        <location>
            <begin position="355"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="86"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="145"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="233"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="305"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH52608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="642" mass="68532" checksum="FD497A328C75617C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N666</accession>
    <name>C1N666_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_63884</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063482.1">
        <property type="nucleotide sequence ID" value="XM_003063436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N666"/>
    <dbReference type="GeneID" id="9688722"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63884"/>
    <dbReference type="eggNOG" id="ENOG502QSRN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125614at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030392">
        <property type="entry name" value="S74_ICA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13884">
        <property type="entry name" value="Peptidase_S74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51688">
        <property type="entry name" value="ICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005667272" evidence="2">
        <location>
            <begin position="38"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S74" evidence="3">
        <location>
            <begin position="354"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="438"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH52618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="470" mass="47463" checksum="624CE493CA443D1A" modified="2009-05-26" version="1">MPRAHDLSRPRGPRTPRAHHVLLFLALALASIRGARAAVLSGADTLTHTASSGNINLAVSSDKGVTVSVGGSTISTTSTSGVDVTGTLSSSAALSTQSTLAVQTTSTFTGQSTFKDNIVLEKAATTITHTAASPASLVISSTNGYVQVETVQFSAANIGVSGATNLVALASGGVTVTGTLVSGAATLASASVTGALSAGATTINGATGITGATTITGATVMKGDVTVKKSDGSATVLTVAGASGNTVVHGLLSVAGAHADTSKKLYVNGDVHATGSITAASSSQGATTITGATSAQGDFTVKASDGSEKFKITAASGNTVVQGLLSVAGAHADTSKKLYVNGDIYATGSTTSASDERFKRDVRALDETLDALREEDVRPVTFNFDAEAHPTKVFPEGPQIGFIAQELERVLPNLVHTGADGFKSVAYDRVSVYALAGVKELAAAVRALSETAREQREAIDALRRELDARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N686</accession>
    <name>C1N686_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42797</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063292.1">
        <property type="nucleotide sequence ID" value="XM_003063246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N686"/>
    <dbReference type="STRING" id="564608.C1N686"/>
    <dbReference type="GeneID" id="9688931"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42797"/>
    <dbReference type="eggNOG" id="KOG1840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="515358at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47689">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47689:SF2">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="215" mass="22460" checksum="16089364C036C761" modified="2009-05-26" version="1">MNPSARCGAVAAAAAAARAAASASPRDAARCEDGADVTAAGPSSSSSSSSSSSSSSSPSPAPLDAPIARAYPSDAASKSTAKWRVYTDIARDHSARGRHADADRYLRRAIAEATNGFGPEDPHVAAAKNNLAESLRLQKRHAEAEKLFKEAAAALERHYGATHPAVGVAWHNYAGCVFARGDHRAAYDAYAAAAEARSDSHWSPYDRVRVVNFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6I4</accession>
    <name>C1N6I4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53327</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063548.1">
        <property type="nucleotide sequence ID" value="XM_003063502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6I4"/>
    <dbReference type="GeneID" id="9689189"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53327"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="237" mass="27125" checksum="79E37F871909AC08" modified="2009-05-26" version="1">MFGGRRLVAKFALGPKKTSFRLEFEFQSDECASCWMFRSLDAPRWAMYADSSDKPWGQQELDHAVWGKPTDAAIERFLRDAGIEDVVVEEAKEAKDAATRRRWTYAKVLCLARRALMEKHGEGGWVEGAENGVYNGMGVHEDEILFTFGFRPAFGVCGFVNDEDDEDDEESDSDRRHERDCWPTEGSDSDRRHAGNWICAEQQQKKNFADAPETCRSSYTDEDTEDAWLARLKKDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6L1</accession>
    <name>C1N6L1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_22787</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063567.1">
        <property type="nucleotide sequence ID" value="XM_003063521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6L1"/>
    <dbReference type="STRING" id="564608.C1N6L1"/>
    <dbReference type="GeneID" id="9689008"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22787"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="515324at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="3">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="232" mass="22681" checksum="DC21A8D82B2C6642" modified="2009-05-26" version="1" fragment="single">MEYAHLGSGGGGGGGGGDRTGGDASPYAATGSALSVAAGRIAFAFGFGSTAVSVDTACSAALTAVHVARSGALHRGGFADDSSRLSNLNLNSYSNSERSASSASSSRHSVCGGANLMLGATNAAAIRAAGMLAVDGRCKTFDAGADGYGRGEACGVFLLRHSGPGGESDSDQKVPIGVLGVRVDASAANQDGRSGSLTAPNGLAQRAAIAEAWRESAPASFPRAVSTHGTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7C0</accession>
    <name>C1N7C0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_53633</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the YOS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063872.1">
        <property type="nucleotide sequence ID" value="XM_003063826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7C0"/>
    <dbReference type="STRING" id="564608.C1N7C0"/>
    <dbReference type="GeneID" id="9689151"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53633"/>
    <dbReference type="OrthoDB" id="15356at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013880">
        <property type="entry name" value="Yos1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15858">
        <property type="entry name" value="IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15858:SF0">
        <property type="entry name" value="IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08571">
        <property type="entry name" value="Yos1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912370" evidence="9">
        <location>
            <begin position="19"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="61"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="113" mass="12410" checksum="60CB061ABD56B93C" modified="2009-05-26" version="1">MTLWTFTQSVLLVLNAFAILNERRFLEKVGLGQSGIHSGYVSSTSPRGQLIGLITATSYMRSASSRRRVRPSPRARPRPARASSSSSSSSSSSLTFRPPRAPPRLPSQCRWSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7N6</accession>
    <name>C1N7N6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_53770</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpA/ClpB family. Torsin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063935.1">
        <property type="nucleotide sequence ID" value="XM_003063889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7N6"/>
    <dbReference type="STRING" id="564608.C1N7N6"/>
    <dbReference type="GeneID" id="9689570"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53770"/>
    <dbReference type="OrthoDB" id="498670at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010448">
        <property type="entry name" value="Torsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10760:SF2">
        <property type="entry name" value="LD13476P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10760">
        <property type="entry name" value="TORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06309">
        <property type="entry name" value="Torsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910674" evidence="3">
        <location>
            <begin position="21"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="346" mass="36189" checksum="2029637BD5F9B257" modified="2009-05-26" version="1">MLPAGAALLVSAAWVILTASTSVRCGADGSFCGDAAARCARLRAVLERDLHGQRVGADLLADALCDHFGGGGGGGGGGGKPLVASLHGSPGVGKSFTHRLVARALYDALDDDDEEEDGDGEREREREREEKAKEKEGPARWIDAAAGLARRVGDGFATSSSSSSSSSSRRRRPRRRPRECPGADCPAYKVIFGVDYVTNEQETQARLLRDALLTHLARFPNAVVVVEEYDKLGAGMLKQMLEKGASAASDARFHDAVFILEANVGFVNIHEHLADADADAEGGGGESHRGEVGEVGEVGEVGEEEDASCTAAAAASCTAAPDRLSSGAFSSHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7X1</accession>
    <name>C1N7X1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53861</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063982.1">
        <property type="nucleotide sequence ID" value="XM_003063936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7X1"/>
    <dbReference type="GeneID" id="9689608"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53861"/>
    <dbReference type="OMA" id="MSHGSTH"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="536" mass="54864" checksum="C34779F0A456880E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1N857</accession>
    <name>C1N857_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66287</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064025.1">
        <property type="nucleotide sequence ID" value="XM_003063979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N857"/>
    <dbReference type="GeneID" id="9689466"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66287"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="184" mass="20973" checksum="D17911F2B94027E2" modified="2009-05-26" version="1">MRSCDVRARVTTIDRRIIRPLQPLLWIRQPAEPAPRPRQRRRRFLPRDRLHRRDRLVVRARLLRAPRVPARHPVRQPIQQRPRRRARVDDDVALRHPAAVHRPRARPGDALRVRVDVHARVGRVRGGEVGTRRGGGGARRRGVVARVVMMPRREHGALDVGERGGGGAAAARRRGDAEQRAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8E5</accession>
    <name>C1N8E5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54052</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064070.1">
        <property type="nucleotide sequence ID" value="XM_003064024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8E5"/>
    <dbReference type="GeneID" id="9689694"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54052"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="515"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="604"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="173"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="515"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="629"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="666"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="754" mass="81865" checksum="15B43CA928AA0210" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8F2</accession>
    <name>C1N8F2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_43313</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064072.1">
        <property type="nucleotide sequence ID" value="XM_003064026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8F2"/>
    <dbReference type="GeneID" id="9689699"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43313"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026317">
        <property type="entry name" value="P_C10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14974">
        <property type="entry name" value="P_C10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912392" evidence="2">
        <location>
            <begin position="36"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="297" mass="31287" checksum="02230D99DDE63E8B" modified="2009-05-26" version="1">MDRADRRRRAPSRLLAVALLVVALALASFATPVAGAHLSVDERMELARSMRKRAGGDPAATTLDTGALHAEARKIAEARAGANRERDAREAAAARREPPRHAKPAMKPSPTPDSYQSSKKDPEEANTSRRASRSSSSSSTRRATSAKMGAASSSSSSSSSSASSPRPPSMTLAQAHAAIDEVTAVVRVPANAARIAAIKKQVDADPDNAMMAMFSFMPLANELMGPAMKKYGYADQENGGGLMPFLNALQEDRGDDALRDKARTLRKLVVPESMLPMVEAMYGGGGGGGGGTRRSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9I7</accession>
    <name>C1N9I7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54518</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064627.1">
        <property type="nucleotide sequence ID" value="XM_003064581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9I7"/>
    <dbReference type="GeneID" id="9690068"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54518"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="273" mass="29252" checksum="1393BD79A141590B" modified="2009-05-26" version="1">MLTADAPVFYDASARRDTLRGSLVPGAPSPDGEEGGAAGGGPFGSSRCWHRRLGCLPPPGLGLRTALDDDDDDDDAAAPKPPPRATAFVSYPRTGKHVAFDGRWLHGAPEALSAKNMSDGKVGGVGKWRTVSDKRRRTTFLVNVWLDHVPSTAAPLPDDALREVSKEPYDDDDDDDDAARAEEAPVDAYEVVEAGETTDEGEMTSLPAFVHAGRTHRASWRLPRRWTRGEGEGGVVDVVACGGGMGRSLAFATEGRVEEVEEEEEEEEEEPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9U6</accession>
    <name>C1N9U6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_67764</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064795.1">
        <property type="nucleotide sequence ID" value="XM_003064749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9U6"/>
    <dbReference type="STRING" id="564608.C1N9U6"/>
    <dbReference type="GeneID" id="9690118"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67764"/>
    <dbReference type="eggNOG" id="ENOG502S5VN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="545910at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF4">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="39"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="233" mass="24611" checksum="AD05AC655B30A6D8" modified="2009-05-26" version="1">MAEDGVGGLAYSGKIMAPTPFTPLMTRLRDEIYDVTGERFDCALINLYPDGECACKWHKDPDLGRLWARDSVIVSVGETRRFAFRKDTTSVKSDVASDHWFRLRGGDCVWMFGACNDTWEHCVMKAEGENNGGARASVVFKRSIPGAGGKRGHGLEGTGRKARAAAAAAAAAKGEGDARAPATSDGRKRREVKAWGADVAGGGGAERRRRGRGGGRGGGRGGGRGGGRGRGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA98</accession>
    <name>C1NA98_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_43724</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064757.1">
        <property type="nucleotide sequence ID" value="XM_003064711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA98"/>
    <dbReference type="GeneID" id="9690308"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43724"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23625">
        <property type="entry name" value="UIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="503" mass="50078" checksum="1CFBA5D7DA03AC16" modified="2009-05-26" version="1">MSGDQEQTEDELLQMAIAMSLQEAAAAAAAAEGGDGASSPALGAEDVTTKRRRVADDDAPGGDDAATTAMDLDEETARAIELSMLERQPGEDDAGAAGATAGEGGGGADAEAAGGAATNPFAALFAPAPASAPASAPASAPASAPASATTTPQSGHPDPPPPPQPVISAAALAAAFGGAAAAAASASAAAPSQPTTRRPRAAAARGGKKRASAVAAPPPPSAEARAALDEWWRRDGEEGDGDAAVAVPDASTACEVLSRVMRAPVVAPGVESSSSSSSSSFSGAPIQISFSQREGGVRVARKMVDALTRTRFSPSRLSSPLGGSVSKASSSACEVIGACHHGACVEAAAAAAAAAASDAAVTADTAALPTTTMLPLLTSLRKSIAKHLLTLLEDDGDDLYFEGGRSRREFADACARGFVAPALIEDVLDQIDTPARSSAWEDTMRQAFKGMGDAALDDVDASESAARAIDALTRSPRCARAVSKGAVPDCVPYDPVREVDADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAC3</accession>
    <name>C1NAC3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54840</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064939.1">
        <property type="nucleotide sequence ID" value="XM_003064893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAC3"/>
    <dbReference type="STRING" id="564608.C1NAC3"/>
    <dbReference type="GeneID" id="9690314"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54840"/>
    <dbReference type="eggNOG" id="KOG1121">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1301613at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47611:SF1">
        <property type="entry name" value="CCHC-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47611">
        <property type="entry name" value="HAT DIMERISATION DOMAIN, C-TERMINAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="2">
        <location>
            <begin position="207"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH50919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="290" mass="33097" checksum="1C8A2CEB7C40ED1C" modified="2009-05-26" version="1">MWKNDEDQELDRITDDSQLHPDVRAMKFGMLQDLRTRCEENSDLVPTLNLKGKVQMCTDNQLVATWLTPRGNSKFRPRKVTDEASSEDRKKFAKHASEEYVERAEKTLKTLLKKVVESQHAKDQEKSQRESRVSSVKKDASSTDEPAFKKQKLDPTSTYGDTDSDEEDACDVVHTERADIEQRLAAAHTEMERFKAHAFNRQVKDETRTSEGLLSWWQVEGIAFPLLREVARNIFSLPASSASSERAFSAAGQVVTHKRKMLDKARVNKLMVVKRNANFVTKAEVLKCIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAG2</accession>
    <name>C1NAG2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54889</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064904.1">
        <property type="nucleotide sequence ID" value="XM_003064858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAG2"/>
    <dbReference type="GeneID" id="9690344"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54889"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="242" mass="26211" checksum="113C097286457FCF" modified="2009-05-26" version="1">MTPLTPPRRARRASADAASLQIAAQSAKQPCPNRARGAATATAARAARRDGGDEVKNTSARALLCFLLRPIARAEIARPRRGLHRRTCPRTPSPLTPHPPRTSRAQNAPPRKRRSPGKPLDRSANFGLFAVARDDVARRESLTAAVIERNWEDVAALAERTNHLADDLGVVATRRIAKTFVTRIESAARAAPATRAKKASSDVKSSVLAQRQQVIRDVTGDDIEGTTPRVCISSRVSSLLRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAG4</accession>
    <name>C1NAG4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54891</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064954.1">
        <property type="nucleotide sequence ID" value="XM_003064908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAG4"/>
    <dbReference type="GeneID" id="9690346"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54891"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH50934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="79" mass="9038" checksum="F511A043E9C907F3" modified="2009-05-26" version="1">MRGCIFAVMIQIKILYHLNQEFFSFLSFAESSGRVSLTEKSCAYEWLCLLSTFPYSSTFSVHLLMLPVLTVLLTLSYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGM0</accession>
    <name>C1MGM0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61091</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054798.1">
        <property type="nucleotide sequence ID" value="XM_003054752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGM0"/>
    <dbReference type="GeneID" id="9680806"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61091"/>
    <dbReference type="OMA" id="WTTRAPL"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="171" mass="19211" checksum="02696DC127A725A5" modified="2009-05-26" version="1">MHCECDFCFLHWPAGARIQIRRRRLRTRASLKARRVPRRRNHLPRPCSRTPPTPPNRTRSPPAPPSRRPRRRRRPSPLRPGSSGVPPPRRLAPPSPRRLTFHIPRLLPPPPHPPRRRGSDPPRASSRCPRNSTSPATTRSPSVAAASCAPGTRESPSSPTTARGWTTRAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGP7</accession>
    <name>C1MGP7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_12329</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055356.1">
        <property type="nucleotide sequence ID" value="XM_003055310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGP7"/>
    <dbReference type="GeneID" id="9680613"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12329"/>
    <dbReference type="eggNOG" id="ENOG502S1EZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IFRDVMA"/>
    <dbReference type="OrthoDB" id="421671at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="288" mass="31802" checksum="FED0AD94EA0E6654" modified="2009-05-26" version="1">MRALASAPTPATRGVVHRRARTRAHRARPRASASDPSSSARPPSARYEKTWSNPTGNVLTDVVPGVVWAAERPFTWNAIDVGGKMAVVRLRDGALWVHSPIDLDDATRAAIDALGSVKHVVSPNYEHVKWAAQWKEAYPDATLYGCPGMRAKKPGIPWDAEVGEDGAPEAWGGEFDVALFDCEVNPFTSTPFFNEVVFCHAASGVAFVTDVFWNYPGGDDVPPGTRLWKFGMDRVYLPFYRAAMVRDREKFARAREKVLSWDFDAALPCHGSFIPRGAKDALRRHLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGS2</accession>
    <name>C1MGS2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">asparaginase</fullName>
            <ecNumber evidence="1">3.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_49919</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055370.1">
        <property type="nucleotide sequence ID" value="XM_003055324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGS2"/>
    <dbReference type="STRING" id="564608.C1MGS2"/>
    <dbReference type="GeneID" id="9680395"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49919"/>
    <dbReference type="eggNOG" id="KOG0503">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CMFGPTS"/>
    <dbReference type="OrthoDB" id="542841at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009066">
        <property type="term" value="P:aspartate family amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08963">
        <property type="entry name" value="L-asparaginase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="entry name" value="L-asparaginase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041725">
        <property type="entry name" value="L-asparaginase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707:SF28">
        <property type="entry name" value="60 KDA LYSOPHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500176">
        <property type="entry name" value="L_ASNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00057">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="L-asparaginase N-terminal" evidence="5">
        <location>
            <begin position="71"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase/glutaminase C-terminal" evidence="6">
        <location>
            <begin position="311"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="active site" description="O-isoaspartyl threonine intermediate" evidence="2">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="176"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="431" mass="45714" checksum="0E1CEED871F7511A" modified="2009-05-26" version="1">MDIRARLKSKSKATSSSARAARAPSLACFAAARRRRAAASDGAGPPAPTGDACTVPARAPTLYQTRPLPSVLVIHTGGTLGMSGDAFHDVEDGALAGAKVFNEGTGGDYAKTLQPGSLLMNLVTAVPELRTFANLEVKVLFNKDSCNVGPREWIGIARELDAQRDRFDAFIVVHGTDTMAYTGTALSLMLAGFRKPIILTGSQLPLAMPRSDARQNLLDAITCATAGFSPPHVQLEEVAVCFGGKLLRANRTRKTSATIYSAFDSPEYPALARLGVGVEWKRDALLQFGNGNGGGSSTTAYTPRMKLETNVIRVPIVPGCDPRKAYGDLYARGVRGIVLEAFGVGNMPGPGKGTHWVSWLRGQHRRGMRLVLTSQCESGDLHPELYATGSSVVEMGVTSGPMMTPECAVVKLMLCLAHPDLPLGQPIAGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGY8</accession>
    <name>C1MGY8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_49988</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054860.1">
        <property type="nucleotide sequence ID" value="XM_003054814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGY8"/>
    <dbReference type="GeneID" id="9680285"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49988"/>
    <dbReference type="OrthoDB" id="498784at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002911965" evidence="2">
        <location>
            <begin position="31"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="590"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="659" mass="68050" checksum="79CD8C28906A4A46" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHL5</accession>
    <name>C1MHL5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50243</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054976.1">
        <property type="nucleotide sequence ID" value="XM_003054930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHL5"/>
    <dbReference type="STRING" id="564608.C1MHL5"/>
    <dbReference type="GeneID" id="9680631"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50243"/>
    <dbReference type="OMA" id="NEHPSMG"/>
    <dbReference type="OrthoDB" id="65716at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090173">
        <property type="term" value="P:regulation of synaptonemal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039057">
        <property type="entry name" value="Spo22/ZIP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375:SF2">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1155" mass="125073" checksum="6C5F094D4BC08B2B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHV4</accession>
    <name>C1MHV4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein phosphatase 2A regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PP2A</name>
        <name evidence="5" type="ORF">MICPUCDRAFT_30915</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055021.1">
        <property type="nucleotide sequence ID" value="XM_003054975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHV4"/>
    <dbReference type="STRING" id="564608.C1MHV4"/>
    <dbReference type="GeneID" id="9680973"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30915"/>
    <dbReference type="eggNOG" id="KOG0211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTLCMTW"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000062">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="9"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="164"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="203"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="242"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="4">
        <location>
            <begin position="275"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="281"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="320"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="359"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="398"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="445"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="484"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="523"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="592" mass="64511" checksum="45D4FCF437552F7D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI04</accession>
    <name>C1MI04_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer dynein arm docking complex 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ODA-DC2</name>
        <name evidence="5" type="ORF">MICPUCDRAFT_50387</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055045.1">
        <property type="nucleotide sequence ID" value="XM_003054999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI04"/>
    <dbReference type="STRING" id="564608.C1MI04"/>
    <dbReference type="GeneID" id="9681150"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50387"/>
    <dbReference type="eggNOG" id="ENOG502QSIU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6766775at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051876">
        <property type="entry name" value="ODA-DC/CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049258">
        <property type="entry name" value="ODAD1_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21694">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21694:SF18">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21773">
        <property type="entry name" value="ODAD1_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ODAD1 central coiled coil region" evidence="4">
        <location>
            <begin position="96"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="454"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="54"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="300"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="465"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="480"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="492"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="509"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="528"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="542"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="560" mass="62367" checksum="2A1E167299F228F0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI51</accession>
    <name>C1MI51_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50439</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055069.1">
        <property type="nucleotide sequence ID" value="XM_003055023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI51"/>
    <dbReference type="STRING" id="564608.C1MI51"/>
    <dbReference type="GeneID" id="9680710"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50439"/>
    <dbReference type="eggNOG" id="ENOG502SBK5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="236" mass="26112" checksum="4AB2F4A3F13BC32D" modified="2009-05-26" version="1">MWTRSSTGFNTIPENVAAVVLSHLTDPEDRVRLAAVSKVWRDAEKGGVASLPGTPSELSELGQEFRSADEQWKAIYWFEKSADHGDPEGMYWLAQYTAYSRSPPPPVCVCGACTEEKNRKAVHWWKRASELGHAEATRMVALSYEHGDGVEIDGSKAIEWHVKAVELGNALAAGWLGNAHYYGLDGLTENDDEALKWFRVAVELGDADARKPSWWEEVLSVSRSMVHVLEANLAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI55</accession>
    <name>C1MI55_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_50443</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055608.1">
        <property type="nucleotide sequence ID" value="XM_003055562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI55"/>
    <dbReference type="STRING" id="564608.C1MI55"/>
    <dbReference type="GeneID" id="9681175"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50443"/>
    <dbReference type="eggNOG" id="ENOG502QQR7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KVEEWYA"/>
    <dbReference type="OrthoDB" id="10254713at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044782">
        <property type="term" value="P:cilium organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042618">
        <property type="entry name" value="IQCG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14871">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14871:SF1">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="456"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="239"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="328"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="486" mass="55302" checksum="C95D8AE81C43313B" modified="2009-05-26" version="1">MATAAPPPAAAEPADEFDAVDVEEGLSKPPPPPTLEPEEAEHVRGVVGRLFEKLRLMSLLKVDPGMQASVSWDRVAAVVAWSSSSSSRANREMPNLDADRSWKPSIHPSSLTARPPLSLPYTRFAQAAEMSRGVGLEISRVMEKQLALETRFEELIKEQPELKARNHKAPFLANQKELHDVTFELRDTTEELCKRLKENPDVMDNIAFAERERAKLQGIIANLLVDLQTGTFCSMTKWIEDEKKREREIKETYERVAAKEAAVAELRQRIIDEREQHAEAMKQREATIGETKEKLKTAKAEIGVDLRYRMRDIEGEASMRDKVNDQALDDLRAEIEKVKKQIAQEKQAHKTTMHHLRKRVEKSNETLAHWQEKHKRDSEKMETEILKVKHKHEETLAKIKEIEPAYLKKKAEDDEKERQRVIWESTVKEREKKAITHARARGNWQLGLDAIAAFKAEGKPLPGAKKDKKGGKGKGDKKGGKKGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI61</accession>
    <name>C1MI61_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_46299</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endomembrane system</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MNN1/MNT family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 25 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055073.1">
        <property type="nucleotide sequence ID" value="XM_003055027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI61"/>
    <dbReference type="GeneID" id="9681179"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46299"/>
    <dbReference type="OrthoDB" id="430354at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046354">
        <property type="term" value="P:mannan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06532">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646:SF1">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycosyl transferase family 25" evidence="13">
        <location>
            <begin position="12"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="221"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="505"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="517"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH60325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="720" mass="75812" checksum="D0AB09D15AAE66D1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIA5</accession>
    <name>C1MIA5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61569</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055635.1">
        <property type="nucleotide sequence ID" value="XM_003055589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIA5"/>
    <dbReference type="GeneID" id="9680584"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61569"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="159" mass="17348" checksum="6556E20032171A1C" modified="2009-05-26" version="1">MATRRGLRAIALAGWKQCAAIAPGADAIACASRSSTPLFARGIVSVARARGDEGWWNRPSAERRSYILSNGHRSSFASSAARPRDFSSSAVVEGDKKSKDDDEEKKKKKTRREKDLLLREGVNENIFAALLGVRPFAILSRSTFSIIHSSLPSSFSRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIA8</accession>
    <name>C1MIA8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50501</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055096.1">
        <property type="nucleotide sequence ID" value="XM_003055050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIA8"/>
    <dbReference type="STRING" id="564608.C1MIA8"/>
    <dbReference type="GeneID" id="9680827"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50501"/>
    <dbReference type="OMA" id="NWGYFAA"/>
    <dbReference type="OrthoDB" id="286233at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044243">
        <property type="entry name" value="FLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47310">
        <property type="entry name" value="PROTEIN FLUORESCENT IN BLUE LIGHT, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47310:SF2">
        <property type="entry name" value="PROTEIN FLUORESCENT IN BLUE LIGHT, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="262" mass="27198" checksum="937025D4ACDF6B14" modified="2009-05-26" version="1">MSALVASSSSSARARAVASRKAALSTRRQIRRPVAARAAASGASDASVSRVDASAASLLPPPTPSTASLVATVAARPATKAPAVASDDVSPFMAFCRANWGYFAALQTIALIGAANNGILAKKRRLEIAEINAKLRAMMQKYEEQQDACDPDGPASRKLSEGKRKLKEDDLDGAVQAFNEAALLVERGDDASALSVAKGVATALIRKGDLAAAIAVLEAKDVVDAAVRDGDGAVYGMLGDCYTDRGEFATAGKYYDKCLSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIH1</accession>
    <name>C1MIH1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50565</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055130.1">
        <property type="nucleotide sequence ID" value="XM_003055084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIH1"/>
    <dbReference type="STRING" id="564608.C1MIH1"/>
    <dbReference type="GeneID" id="9680980"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50565"/>
    <dbReference type="OMA" id="DCVLQPN"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002911924" evidence="2">
        <location>
            <begin position="28"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="304"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="478"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="663" mass="69744" checksum="587D2744287F5CC7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MII2</accession>
    <name>C1MII2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50576</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055670.1">
        <property type="nucleotide sequence ID" value="XM_003055624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MII2"/>
    <dbReference type="STRING" id="564608.C1MII2"/>
    <dbReference type="GeneID" id="9680999"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50576"/>
    <dbReference type="eggNOG" id="KOG3654">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2125658at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.360">
        <property type="entry name" value="CKK domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032940">
        <property type="entry name" value="CAMSAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014797">
        <property type="entry name" value="CKK_CAMSAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038209">
        <property type="entry name" value="CKK_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21595">
        <property type="entry name" value="PATRONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21595:SF0">
        <property type="entry name" value="PATRONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08683">
        <property type="entry name" value="CAMSAP_CKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01051">
        <property type="entry name" value="CAMSAP_CKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="PRC-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51508">
        <property type="entry name" value="CKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CKK" evidence="2">
        <location>
            <begin position="881"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="647"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="515"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1017" mass="106158" checksum="84F485A64B2AA03D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIL9</accession>
    <name>C1MIL9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46355</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055689.1">
        <property type="nucleotide sequence ID" value="XM_003055643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIL9"/>
    <dbReference type="GeneID" id="9681208"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46355"/>
    <dbReference type="OMA" id="ICSHITH"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="321" mass="36783" checksum="9D089B06879321C6" modified="2009-05-26" version="1" fragment="single">HSSRADVPSCPPPSRASPRRSTRARRRRRRRRRRRRHRDDPVAVPIVANAPGRARPRLQPGDAGRGDIHHLAAHRGRRAERLPRVRIPARRDARVRGDQRHDPGRFDARRRRRGPSRRGVHGVHLRLRRRVRRGGGRLYAPGGRRRRDRRRRGRRGRRRRRRRRAAGNLHGGSRAVPQRRRRPSRARRRRRRRRSRRRSRGEGEGAQGGAQTRGADDAKSAAVADEQSQCAGASGGGGADEGAAHADAKGAARDEDRGDGGKRRRRDGRELGGGEADACGCQRGVPSAHRRRGEALARRRRRRRRRRRRRRRVTFGLVIKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJI6</accession>
    <name>C1MJI6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55838</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056217.1">
        <property type="nucleotide sequence ID" value="XM_003056171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJI6"/>
    <dbReference type="GeneID" id="9682069"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55838"/>
    <dbReference type="OMA" id="CKSAGWR"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="281" mass="31044" checksum="2F9FDAE496A9951C" modified="2009-05-26" version="1">MASRLTSPLSLLAVNRERNDNEGHDAVSPDPGNSPGMPGGSPMQLGATTTLQSPRQSRESAPPSREYGDSDGDLFTPPQGVRARRRRRSEVWGDTPTRSSSRTRPSEQVSASPEVPPPPAFFVRASGTNASESDKLRFIRAVEANKAKGISVAATTARWGFSKNAYAKYKKQDKLGETKPKVIPGRPQKADEEIKAKLYEVNRAFQGGLTIEGLSKELLRIFGVYLSPSTICRMMTRDGWRKRKKRSSPFLTEKAMTARAEGTHTRTGSTHRKYFRTPVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJL0</accession>
    <name>C1MJL0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55001</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056231.1">
        <property type="nucleotide sequence ID" value="XM_003056185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJL0"/>
    <dbReference type="GeneID" id="9681871"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55001"/>
    <dbReference type="OrthoDB" id="423807at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="70" mass="7570" checksum="3C8AFEEB6EE32170" modified="2009-05-26" version="1">MERPSACGSLARFVTAYASTGGGGHLTSHERTFLAIAWTPKATVQAALRRVHLYSHWSPYDRVGAVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKD9</accession>
    <name>C1MKD9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MCM9</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_55301</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056368.1">
        <property type="nucleotide sequence ID" value="XM_003056322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKD9"/>
    <dbReference type="STRING" id="564608.C1MKD9"/>
    <dbReference type="GeneID" id="9681330"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55301"/>
    <dbReference type="eggNOG" id="KOG0477">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ISIRLTH"/>
    <dbReference type="OrthoDB" id="496750at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF48">
        <property type="entry name" value="DNA HELICASE MCM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="7">
        <location>
            <begin position="387"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="791" mass="87223" checksum="89DC817F290AF1AC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKI3</accession>
    <name>C1MKI3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_55351</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056001.1">
        <property type="nucleotide sequence ID" value="XM_003055955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKI3"/>
    <dbReference type="STRING" id="564608.C1MKI3"/>
    <dbReference type="GeneID" id="9681955"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55351"/>
    <dbReference type="eggNOG" id="KOG2899">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NMEQEGT"/>
    <dbReference type="OrthoDB" id="10017101at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017069">
        <property type="term" value="F:snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040031">
        <property type="term" value="P:snRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039772">
        <property type="entry name" value="Bin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010675">
        <property type="entry name" value="Bin3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024160">
        <property type="entry name" value="BIN3_SAM-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315:SF0">
        <property type="entry name" value="7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315">
        <property type="entry name" value="BICOID-INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06859">
        <property type="entry name" value="Bin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51515">
        <property type="entry name" value="BIN3_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bin3-type SAM" evidence="9">
        <location>
            <begin position="105"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="377" mass="40947" checksum="B49EFE9CAFA9FE66" modified="2009-05-26" version="1">MAAVPNEDPPPHTIATSLNARGKRAPGEQYGKSSTAKRLASGLDAWASEGAVSSRAEDDGDGATTLDAGRTSNAPSKPGRKRHVCFRYGNYHRYYGYRVGASLEDHRVSHLDAKWFEGKRVLDIGCNEGLVSLSVAVNFKPNSVIGIDIDPHLVDQAQRKLQRLRRAAAAAARRLEKAMAVAAGEHLGAERTSIVDALAGSSSDSVGEVSVGIRADETRTAGGIRTASADDEEVVNDYAPGFPQSRVDLTDAAPSLGGVTFRHGNILHEANTPNSFDVVLCLSVTKWIQLNWGDVGVKKMFKYVYDSLAPGGVFVLEPQPWKSYRQAFRKQKMPEETRAHYRAITLRPSQYAGWLVGPECGCVFVLALDVHCFPFHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKN3</accession>
    <name>C1MKN3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_24904</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056418.1">
        <property type="nucleotide sequence ID" value="XM_003056372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKN3"/>
    <dbReference type="STRING" id="564608.C1MKN3"/>
    <dbReference type="GeneID" id="9681967"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_24904"/>
    <dbReference type="eggNOG" id="KOG0275">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MMKQQEP"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045184">
        <property type="entry name" value="SMU1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054532">
        <property type="entry name" value="TPL_SMU1_LisH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17814">
        <property type="entry name" value="LisH_TPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CTLH" evidence="4">
        <location>
            <begin position="42"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="223"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="261"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="304"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="345"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="513" mass="57612" checksum="D4B584CC1303335B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLG8</accession>
    <name>C1MLG8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65042</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056165.1">
        <property type="nucleotide sequence ID" value="XM_003056119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLG8"/>
    <dbReference type="GeneID" id="9681589"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65042"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="136" mass="15208" checksum="85DD446CC882D594" modified="2009-05-26" version="1">MSHVENRNPTRFSQGSVGRVSQSEAAVPASDWSADVASARDGRAHRHATHPRATRIVFNGNGHLHADMRATRCPSGAGPRPARDTGEFCLFFLAPPSRRHLVTRVHATITWIPARRKALRNDRDRYRVRPHDSRCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLI1</accession>
    <name>C1MLI1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55723</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056569.1">
        <property type="nucleotide sequence ID" value="XM_003056523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLI1"/>
    <dbReference type="GeneID" id="9682037"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55723"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="58" mass="6464" checksum="986A03B14747E6DC" modified="2009-05-26" version="1">MEYDAYAPDSTRLAKSGSAYRVLGHDAATYYQYAIYVSLITNISLPDPCTLSERATLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLN5</accession>
    <name>C1MLN5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">26S proteasome non-ATPase regulatory subunit 4 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">26S proteasome regulatory subunit RPN10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_25348</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S5A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056597.1">
        <property type="nucleotide sequence ID" value="XM_003056551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLN5"/>
    <dbReference type="STRING" id="564608.C1MLN5"/>
    <dbReference type="GeneID" id="9681606"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_25348"/>
    <dbReference type="eggNOG" id="KOG2884">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ILACMHD"/>
    <dbReference type="OrthoDB" id="1731724at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000005">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="6">
        <location>
            <begin position="5"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00071116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="350" mass="37090" checksum="4936BA7E3EC50327" modified="2009-05-26" version="1">MVLEATIICIDNSDHVRNSDYLPTRLQAEADAINLLAGAKTQSNPENSVGVLSLAGSVPKVLVTPTDDLGQVLNSVHGISTEGAVNFSTGIQVAHLALKHRQNKHQRMRIVLFIGSPINTEHGELIAVGKKLKKCNVAVDVVSFGDVQKNAEKLSAFIEAVSKNGNSNLVTVPPGEILADVLLNTPIFLDEDSCNHGSGFAAAAAAAAGQVALQGFNSTAGVNGEDDPALLMALRVSLEEERARQEAQAQTATDVNAPPTDTKVLTATIISDEEERTISPSSIGADSVLSDSVLLQQAFALSVEDTFHDDSVQDACVNEAEFKNDHRQANLHASEGKEKEAEDTQNKGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLV2</accession>
    <name>C1MLV2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_56278</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dpy-30 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057283.1">
        <property type="nucleotide sequence ID" value="XM_003057237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLV2"/>
    <dbReference type="GeneID" id="9682722"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56278"/>
    <dbReference type="OMA" id="QRPEEPF"/>
    <dbReference type="OrthoDB" id="417678at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22965">
        <property type="entry name" value="DD_DPY30_SDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007858">
        <property type="entry name" value="Dpy-30_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049629">
        <property type="entry name" value="DPY30_SDC1_DD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05186">
        <property type="entry name" value="Dpy-30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="18"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="353" mass="36743" checksum="45369EF98471E8A9" modified="2009-05-26" version="1">MSDEPETVPPAEPEAEAEAPAAEAETEAAPAEAEAPAAEEAAPEESPAPAEDAAAEEPAAAEEPAAAEEPAAAEEPAVTEDAPAAEDAPAAEDAPAAEEAPAAEDEAPAAEDEAPAAEDEAPAAEDEAPAAEEAPAATEGDAEPATKIDAPDDVDPDEDAAAAPEPTPEPEPADVESEPEPDVGTDDAFKENAAPPFERANDDRAPPGEPLFAKKQPVHAYLASNIQLAVRHALRALSSQRPEEPFALAADVIREWTPEATAPRLSRPAGGNSIGAREYLEKTQILNALHEGMCQMAKIRPADPRQFLADYLLDHAPAPEYVQQMERFGTEEQLAKMDALHEGARDALDGMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLV7</accession>
    <name>C1MLV7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_56282</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CFAP144 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056832.1">
        <property type="nucleotide sequence ID" value="XM_003056786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLV7"/>
    <dbReference type="STRING" id="564608.C1MLV7"/>
    <dbReference type="GeneID" id="9682271"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56282"/>
    <dbReference type="eggNOG" id="ENOG502SC2E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EYEMESA"/>
    <dbReference type="OrthoDB" id="446290at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097546">
        <property type="term" value="C:ciliary base"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029214">
        <property type="entry name" value="CFAP144"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33865">
        <property type="entry name" value="PROTEIN FAM183B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33865:SF3">
        <property type="entry name" value="PROTEIN FAM183B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14886">
        <property type="entry name" value="FAM183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="148" mass="16887" checksum="E8E3442A1BC22BAC" modified="2009-05-26" version="1">MPAAAFDPVAKNRIWKEFCDRETATIKLNTHFSVSDPSKLDVFPEKPNNMVPELSLDQAEMDEANDKLRELCTVRDAFKPPQEKYDLPMTSSQEIGWATRMLMPRNPMFHKPRNSCDITRYADAYYADKGVTPFTQVGPKFADPNQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMF8</accession>
    <name>C1MMF8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56512</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056921.1">
        <property type="nucleotide sequence ID" value="XM_003056875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMF8"/>
    <dbReference type="GeneID" id="9682360"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56512"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="529" mass="56654" checksum="E481C222FD04B45C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMN6</accession>
    <name>C1MMN6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Equilibrative nucleoside transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_3936</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057437.1">
        <property type="nucleotide sequence ID" value="XM_003057391.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMN6"/>
    <dbReference type="GeneID" id="9682399"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3936"/>
    <dbReference type="eggNOG" id="KOG1479">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NEWWFTI"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002259">
        <property type="entry name" value="Eqnu_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332:SF10">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01733">
        <property type="entry name" value="Nucleoside_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016379">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="371" mass="39420" checksum="62617D3EF904E449" modified="2009-05-26" version="1" fragment="single">DHKNVAYWSCVALGAGILFPWNAWITAVDYFEMTYPGRHVDRVFPVLYFFPNVCALLVVLKHGHRLSQRARVRGGFVVFLLCLLAPAFASFAVVCVAVALTGAADAFAQGSLFGVVAPMPPSHTQALMAGTSVSGLVIATLRLTTRAAFGEANVRTAAGAYFGVAAAWVLACVALHGVLERTEMYAYYTREKDGGGDYVTVPRDVLRRAWPQAVSVYAVYAVTLSIFPGVLAEDVSSAKLGSWYPLVLIACFNLFDVVGKAAPALAPALAARAGGDARALLTLALTRVLFVPAFVCVSARRGFEALSANELPCVLLVMALGWTNGWVGAVAMMAAPEAAEASRREACGTVMVLFLLSGLTTGAFCGWLWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN87</accession>
    <name>C1MN87_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56823</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057062.1">
        <property type="nucleotide sequence ID" value="XM_003057016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN87"/>
    <dbReference type="GeneID" id="9682975"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56823"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="50" mass="5638" checksum="12469C4242A2289E" modified="2009-05-26" version="1">MSPSAAAHPAWRVAVLRALEKNKARRLSRRRRRRRAIAPSRVASSPPPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNW4</accession>
    <name>C1MNW4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_38612</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056715.1">
        <property type="nucleotide sequence ID" value="XM_003056669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNW4"/>
    <dbReference type="GeneID" id="9682621"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38612"/>
    <dbReference type="OMA" id="WIDARET"/>
    <dbReference type="OrthoDB" id="442087at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912042" evidence="2">
        <location>
            <begin position="24"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="31"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH58360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="490" mass="52850" checksum="8958CD18BD04731E" modified="2009-05-26" version="1">MARAAGVLLAALLLVAAARGGSGERALDVRAARLELGLDADRDGASSHRVVESVDELKAAFRRASLRAHPDKEGGSHESFVRVAEAYRVLRENADGGGGARWSDFAPPQSSAYWDGPDAGGAREGAGGGDFSGGYPRRHRHRDEEDDASSRASRQRARREREVREQKFDEFFRSQRAWADAAGGGAGAGRDGGFATRRASSSAASAAAASGGRRWYEHEQRNRKSRARPEPPPPSGGSGGHPRHHRAAEDARDDAGGFAPRPRQNRAQNQNQKWWARGDADGAGNNPNARDYHFRHGGRRVPPRATPEGSSAYPPEGSGGAARGPWDVDPWDAEARRAAARGASGEDAREYEYEYARYVDEWIDARETYPHDDDVESMEEYVRRRAWADARGVGGHDRRVGGGAFGDAFGAFGGERERFGDEDVDGGERRDDGGRDGGAGGAWGERSDDEREDVEREAVPVTDVGEAFGVDELCAAGVADYCWGTHATRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP64</accession>
    <name>C1MP64_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_32230</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057231.1">
        <property type="nucleotide sequence ID" value="XM_003057185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP64"/>
    <dbReference type="STRING" id="564608.C1MP64"/>
    <dbReference type="GeneID" id="9682205"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32230"/>
    <dbReference type="eggNOG" id="ENOG502QRZ6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TMWGDED"/>
    <dbReference type="OrthoDB" id="497837at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056376">
        <property type="entry name" value="DEX1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045232">
        <property type="entry name" value="FAM234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21419">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21419:SF23">
        <property type="entry name" value="PROTEIN DEFECTIVE IN EXINE FORMATION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23722">
        <property type="entry name" value="Beta-sand_DEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910378" evidence="8">
        <location>
            <begin position="27"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="850"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="domain" description="DEX1 C-terminal" evidence="9">
        <location>
            <begin position="741"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="201"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="348"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="896" mass="96307" checksum="A6AE9A84AB6AB8B2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP95</accession>
    <name>C1MP95_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_4866</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056781.1">
        <property type="nucleotide sequence ID" value="XM_003056735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP95"/>
    <dbReference type="STRING" id="564608.C1MP95"/>
    <dbReference type="GeneID" id="9682686"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4866"/>
    <dbReference type="eggNOG" id="KOG1763">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AMIFKPV"/>
    <dbReference type="OrthoDB" id="278280at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032378">
        <property type="entry name" value="ZC3H15/TMA46_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12681:SF0">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12681">
        <property type="entry name" value="ZINC FINGER-CONTAINING PROTEIN P48ZNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16543">
        <property type="entry name" value="DFRP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="153"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="153"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="249"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH58426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="285" mass="32790" checksum="DC679C870EC8425A" modified="2009-05-26" version="1" fragment="single">DKIFGLKNKNTSKHAQDFVKDVERNMKVLPGEQQKAEAKRRENEKLKLAKIQAEKELEEMMGELIKQPKVPEGVDPKTIACEFFKKGRCAKGWRCKFSHEKKSARAEAAKADLFMDLRDEETKAKDADAMEDWDQTKLESVVSEKHGGENQNNKTNITCRHFLEAVEKRLYGWFWVCPNGGDECKYRHALPPGYVLKSQIAAMLAEEKEAQRTEEEMLEEERGKMSEGTLVTEAHFAIWKKERDARRRESIEAAKEKRHAEGRLSGRELCETGEDPFAVDDDDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPV4</accession>
    <name>C1MPV4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57052</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057652.1">
        <property type="nucleotide sequence ID" value="XM_003057606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPV4"/>
    <dbReference type="GeneID" id="9683452"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57052"/>
    <dbReference type="eggNOG" id="ENOG502RZZH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PREEVEW"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046824">
        <property type="entry name" value="Mss51-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069">
        <property type="entry name" value="GH20023P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20179">
        <property type="entry name" value="MSS51_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial splicing suppressor 51-like C-terminal" evidence="2">
        <location>
            <begin position="53"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="324" mass="35077" checksum="57A473F65DDACADB" modified="2009-05-26" version="1">MSWSSVRGGGDDDDDELAIAFAHEHSRAFTILEAVERVRAHRVRVEEDAASKSRHHPPKRDDTLRVLVVGADRVEGTNPEATAEVFRAVLERGGVGDDARGFANVEILCAGPNVTVDDGIAEGEFHAVRGADDDEEEEDDEDDEEAPSPKRRRAGVSVGYHVGLYHDIASEGEEEEEEEEEADAPAERKASTASTFSGWVPELAVAFNAGMWGYSQDEWRPTIDRIVHAHKCPLVVTGYTVKEAESDEDALRAMTTPAAAADAGGGAGAGVEWLWETEANPFRSLRPRALRFDRSVYVPGDDAGDGEGAFMGENAAWMCLRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQG2</accession>
    <name>C1MQG2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 32 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57280</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057752.1">
        <property type="nucleotide sequence ID" value="XM_003057706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQG2"/>
    <dbReference type="STRING" id="564608.C1MQG2"/>
    <dbReference type="GeneID" id="9683190"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57280"/>
    <dbReference type="eggNOG" id="ENOG502RJ0F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EMAYSRH"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039367">
        <property type="entry name" value="Och1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834:SF1">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="798"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="974"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="994"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1059"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1079" mass="117789" checksum="0EA433E3F3667E1B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQW0</accession>
    <name>C1MQW0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57431</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058198.1">
        <property type="nucleotide sequence ID" value="XM_003058152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQW0"/>
    <dbReference type="STRING" id="564608.C1MQW0"/>
    <dbReference type="GeneID" id="9683262"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57431"/>
    <dbReference type="eggNOG" id="KOG0907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAPCERF"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050620">
        <property type="entry name" value="Thioredoxin_H-type-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10438">
        <property type="entry name" value="THIOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10438:SF468">
        <property type="entry name" value="THIOREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="58"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="179" mass="18412" checksum="5019E2066CFF92E5" modified="2009-05-26" version="1">MDAGAAPWWAAPATSSIVATSRRADDDAGAASSSGAFGCDVRDARTGARRRPRGRDAGASSRPAIGATSSAPASAMDGPTLRAALAASPRIVVNVTASWCAPCERFKPKFADLSGAFPDVAFVSVDVDALDDDAVDALGVETVPTFLLMRDGEEKTRIVGIAHKRPAKPIAAAIRAHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR09</accession>
    <name>C1MR09_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57483</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057846.1">
        <property type="nucleotide sequence ID" value="XM_003057800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR09"/>
    <dbReference type="GeneID" id="9683663"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57483"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="303" mass="32994" checksum="ABAED37E5FFB9C85" modified="2009-05-26" version="1">MPAVRRATRASDRPAPRAPSSSSDPDDDDVSRASRGRGRAPGEDVSAEWTSERVVECRRAWRLAVLRQNAPVHQTGQLMTIAIALAVAFKKPAPLVGLKPEWTRRVPVSGAAAALAAAYVAAIACQVANPHRYEKNYEVACELLSWGGILAGQYTLMMNGPGMLSRLRPLTLMGSIIMMRFEFSKQRLWFALRMVAETCLEAGRHALEGAHGGDFARCLVDKIPIGLVKIAFGLQLLWLLERRDKARFLESYSSSEEEARLAAAAIERRRGDGGGTMSASRLARGTGVAILVAVGVYQMFLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRW7</accession>
    <name>C1MRW7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_44340</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058945.1">
        <property type="nucleotide sequence ID" value="XM_003058899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRW7"/>
    <dbReference type="STRING" id="564608.C1MRW7"/>
    <dbReference type="GeneID" id="9684021"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44340"/>
    <dbReference type="eggNOG" id="KOG2903">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HGWTAAW"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03190">
        <property type="entry name" value="GST_C_Omega_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047047">
        <property type="entry name" value="GST_Omega-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="GLUTATHIONYL-HYDROQUINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015753">
        <property type="entry name" value="GST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="177"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="142"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH57400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="343" mass="36970" checksum="DF5C87549351D7BA" modified="2009-05-26" version="1">MMTELAPSDDAGAYVRPSYGFDDTLSNDPTAKHPAMCGRYVVYVGNACPWCHRVTLTIALKGLSDAIAVVKMTDDAERASRGGWVFEQFPASARDPVFGARDLREVYDAAVMSKGPAGAPYRGRCTAPLLLDAARKTPVCNESADIVRALNDVDFVGVGQGVGQGVGQSDAEEGVVELRPAALLDEIDAWGEEVYRGLNNGVYRCGFATSQAAYERAATDVKTTLLKVEKRLSESRFLCGDKITEADVRLFPTIVRFDAVYATLFKCSNVRVADLPCVSGFMKDVYALPGVRETVDLAGYRSSYFGQLFPLNPGGIVPIGPTEADLGLGEDANRGTGDVFHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRW9</accession>
    <name>C1MRW9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58261</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058946.1">
        <property type="nucleotide sequence ID" value="XM_003058900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRW9"/>
    <dbReference type="GeneID" id="9684022"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58261"/>
    <dbReference type="OMA" id="FWRNSCY"/>
    <dbReference type="OrthoDB" id="10680082at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="339" mass="34624" checksum="4E4839162A7D42C2" modified="2009-05-26" version="1">MHGGRGGGRGGRGAGTAAAPITLDDDAMRPPPAQHAKEPSGAPPLYPPLIRMPPPPVPTEREMELLKIKRELHAFWRNSCYYLDSEPERGEHPEVVVEQYADKVERERAKSAPSKLARLREIIKDDAAYFPAELFACLGIPSGGDGGAGGGGTAGGKAASGGGGGGGGGGARGKKRARGDASAASGDGDGDDDDDDDGGRIGRLEKLAKLEKEREEEARAAAEGAGGGGSGGGGRELRRGSRRVSFKEEDKAAAATGGKAGGGAGKPSTSTDAGKPSGGGGGATTSDDATKDDGDESDGGKEEEDDWDDEDEYQRGETFDDDDGYEDDVGGDGDDEAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS84</accession>
    <name>C1MS84_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58385</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058639.1">
        <property type="nucleotide sequence ID" value="XM_003058593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS84"/>
    <dbReference type="STRING" id="564608.C1MS84"/>
    <dbReference type="GeneID" id="9684444"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58385"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="219" mass="24055" checksum="B4515B26954FF57B" modified="2009-05-26" version="1">MSFDDVPENVAAVVFSHLGNDPIDRVRLAAVSKVWRSAEKADASLPVAPGELFSLGEVWFRQYPLDGHHQSMKAIYWWSKAAATGDADAMCAIGSCYRVGEGVKQDHTKAVEWWEKASRRGHADATHKLAWCYKYGTAVERDGGKALELYLKAVELGSAEAAWNLGVIYRYGRSDGMVAVDKKEALKWYRVTAERGGSDTVAKSIVAELEAELAAETTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS98</accession>
    <name>C1MS98_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_39965</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PIERCE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058645.1">
        <property type="nucleotide sequence ID" value="XM_003058599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS98"/>
    <dbReference type="STRING" id="564608.C1MS98"/>
    <dbReference type="GeneID" id="9684452"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39965"/>
    <dbReference type="eggNOG" id="ENOG502SDJS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CYATSAN"/>
    <dbReference type="OrthoDB" id="546383at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026507">
        <property type="entry name" value="PIRC1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20899">
        <property type="entry name" value="PIERCE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20899:SF1">
        <property type="entry name" value="PIERCER OF MICROTUBULE WALL 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14892">
        <property type="entry name" value="PIRC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="481" mass="51049" checksum="331CDABE7107FECD" modified="2009-05-26" version="1">MESTQGATGLMFGLETSRPRGSVAFEATTNHTAKTTALILASSHGAALAAEMGSANGGKLTKKALLPVHDALVVEHWLNAIARCDGAIANVLIAHNKDDAAAFEAWAASGAMPANASLVCAENAAASDADADARGGIAADLLHVAESAAHDRANHLLVIDGEHVPEPDYDLRSVLDHARSRGKDVFTFVDVDFGGEGATPSEHVLLKLRDNGAGGRVTFPEVLGAAPYPDASAWDGNTAALGPVTFLRRGTTPLVRAFFDTVAPSLRCAASERFGHLMSYVQCNVIVHALEMKHAFSVKTLGAYEHACDVFKFYAEEKEKASAKFATLKTGGVGAARDDARAKILREKIHARTSRAGDYRLRAVAAEADMDVVLSKYNAMKASENMTESFAKRLGIPGAVLPPRFADAAAWKLEVPKQHACYATSANVYGAKRVTPADMPMRWHGVKGDFTDRFGGAMYKDDGLVVGIDKSNVHRALDGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSJ8</accession>
    <name>C1MSJ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Voltage-gated ion channel superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_47192</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058693.1">
        <property type="nucleotide sequence ID" value="XM_003058647.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MSJ8"/>
    <dbReference type="GeneID" id="9683820"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47192"/>
    <dbReference type="eggNOG" id="KOG2301">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EWHITML"/>
    <dbReference type="OrthoDB" id="416585at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001518">
        <property type="term" value="C:voltage-gated sodium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005248">
        <property type="term" value="F:voltage-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.350:FF:000009">
        <property type="entry name" value="Voltage-dependent T-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000117">
        <property type="entry name" value="Voltage-gated Ca2+ channel, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043203">
        <property type="entry name" value="VGCC_Ca_Na"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037:SF62">
        <property type="entry name" value="SODIUM CHANNEL PROTEIN 60E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037">
        <property type="entry name" value="VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="556"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="626"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1001"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1085"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1198"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1322"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1417"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1510"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="13">
        <location>
            <begin position="59"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="13">
        <location>
            <begin position="428"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="13">
        <location>
            <begin position="961"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="13">
        <location>
            <begin position="1288"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="659"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1589"/>
            <end position="1616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1708"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1793"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="667"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="721"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1589"/>
            <end position="1600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1711"/>
            <end position="1725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1819"/>
            <end position="1829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH57148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1844" mass="203693" checksum="4A65EAA1383220B2" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MST1</accession>
    <name>C1MST1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_57811</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058732.1">
        <property type="nucleotide sequence ID" value="XM_003058686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MST1"/>
    <dbReference type="GeneID" id="9683793"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57811"/>
    <dbReference type="OrthoDB" id="2013641at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="122" mass="13133" checksum="47278D61E3C97ED0" modified="2009-05-26" version="1">MTDEEGGGFGLDARTRYARQCDLPEPGSSRVTAAARANEKNTCVDVCAEFTGVKDCQTRCVQDADDKKHACREACQVAFGNACDRAFPASGDDGSTNFKICLSYMATSCHDTCKKFRGVGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTK2</accession>
    <name>C1MTK2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_58102</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058505.1">
        <property type="nucleotide sequence ID" value="XM_003058459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTK2"/>
    <dbReference type="STRING" id="564608.C1MTK2"/>
    <dbReference type="GeneID" id="9684316"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58102"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018788">
        <property type="entry name" value="Proteasome_assmbl_chp_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053720">
        <property type="entry name" value="Psm_Assembly_Chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10178">
        <property type="entry name" value="PAC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="160" mass="16548" checksum="572EDF19311A128D" modified="2009-05-26" version="1">MTTTSTPPARPPQRAVRTSQRAWIIEGVHTECLVTDYDDRALVVVTQVAKLGLVFHAAGGSVERGGGDGGNLPGHYAPKLRALSGGGRKDDELVQAVASRVVQVVRGAGVDKPVIVSMGLEKAFREMDALRGMARVCGDFAAEALSGVVPPSSAAVSAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTM5</accession>
    <name>C1MTM5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_17420</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058885.1">
        <property type="nucleotide sequence ID" value="XM_003058839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTM5"/>
    <dbReference type="STRING" id="564608.C1MTM5"/>
    <dbReference type="GeneID" id="9683959"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17420"/>
    <dbReference type="eggNOG" id="KOG1985">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HTFISEQ"/>
    <dbReference type="OrthoDB" id="49016at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF17">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="2">
        <location>
            <begin position="269"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="3">
        <location>
            <begin position="550"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="774"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="818" mass="86687" checksum="94D8D69CC676C8C7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTM9</accession>
    <name>C1MTM9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58130</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058522.1">
        <property type="nucleotide sequence ID" value="XM_003058476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTM9"/>
    <dbReference type="GeneID" id="9683961"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58130"/>
    <dbReference type="OMA" id="NFPPHLH"/>
    <dbReference type="OrthoDB" id="198198at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="17528" checksum="917E44741F3582CE" modified="2009-05-26" version="1">MGDGDATTAPDAVPEGATPFRVPEGATSMEVPKAFSALKVVPKEGEANDANFPPHLHAAVELFCFAKMPECAKKLATAVNAYLAILSAGPDGKGTNGMGQAAVCWECGHCGLPGNQDECGKGKDAKCGDCGSSAQTNMVKVTQPDGTVVPWIEPKQAPAGKAEEAAAAADALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTP5</accession>
    <name>C1MTP5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_58498</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the zinc-containing alcohol dehydrogenase family. Class-IV subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059058.1">
        <property type="nucleotide sequence ID" value="XM_003059012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTP5"/>
    <dbReference type="STRING" id="564608.C1MTP5"/>
    <dbReference type="GeneID" id="9684796"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58498"/>
    <dbReference type="eggNOG" id="KOG0022">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3297">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="417550at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051903">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.180.10:FF:000067">
        <property type="entry name" value="alcohol dehydrogenase 1-like isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000003">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF12">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE CLASS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="10">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="11">
        <location>
            <begin position="356"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="9">
        <location>
            <begin position="530"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00060764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH56190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="711" mass="76094" checksum="1A7ED96719D5DF34" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUE8</accession>
    <name>C1MUE8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_40193</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059483.1">
        <property type="nucleotide sequence ID" value="XM_003059437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUE8"/>
    <dbReference type="GeneID" id="9684624"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40193"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="194" mass="19835" checksum="2D7BAD4358395DB9" modified="2009-05-26" version="1">MGGWKDDPSPSPSSSRRAPDVDRAKPFAPSRRDGAAGGDWRDAMRDVKRAASASGASARDELRRATRAFFDAASGRAHPPLGDAKPSEIAADVVLLARAINASDASSPSPSSSPSPSPPRDAFDALLTDLLSAGSPSAGKVAVDAETVAALGAYYRGVLSSPSCAPSTADDALRVTTLLLQEGGAHVTPSEDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW78</accession>
    <name>C1MW78_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_9388</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060169.1">
        <property type="nucleotide sequence ID" value="XM_003060123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW78"/>
    <dbReference type="GeneID" id="9685315"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9388"/>
    <dbReference type="OrthoDB" id="514051at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47426">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASES (NAT) SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47426:SF3">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="62" mass="7022" checksum="6AF473AB16BA9C6C" modified="2009-05-26" version="1" fragment="single">YLANVAVAPEARRQGVASAIIEKSERVAKMWGYDELWLHVNVDNPSAKKLYERAGYAFHSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWB3</accession>
    <name>C1MWB3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_65600</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060185.1">
        <property type="nucleotide sequence ID" value="XM_003060139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWB3"/>
    <dbReference type="GeneID" id="9685334"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65600"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="253" mass="27850" checksum="B44B39AD7D189883" modified="2009-05-26" version="1">MIDTITFKRPPTTARERGVGEPPSFARALLRPAALRPRPPANAIHQPRRRDDDDEILNHGHEPLVFVVLVQRLPPRVRLLRGRPALPLHLRNHPRVHVILRVLPAVRLAVRRGEPLSLLMVLRAHHPGPDVRVRVHPSVSIRDEIIRRRVRARDHAVPEPGLGVLRRVDVGPALVEDAVARRRARGHHTGAEAGGVVLAGVAVRAILREDALARGVLARDEPAADARLGVLVRELPAVLAIVQARGVVLDGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWC0</accession>
    <name>C1MWC0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_59709</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060189.1">
        <property type="nucleotide sequence ID" value="XM_003060143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWC0"/>
    <dbReference type="GeneID" id="9685337"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59709"/>
    <dbReference type="eggNOG" id="KOG0474">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="428525at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051280">
        <property type="entry name" value="Cl-channel/antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689:SF161">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="10 12" id="KW-0868">Chloride</keyword>
    <keyword evidence="7 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="523"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="658"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="683"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="715"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="746"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="807"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="1069"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="283"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="364"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="905"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="973"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="922"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="983"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1022"/>
            <end position="1032"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH56141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1122" mass="117699" checksum="36B82E6D86DF42EF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWG0</accession>
    <name>C1MWG0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Decapping nuclease</fullName>
            <ecNumber evidence="2">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_59753</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the DXO/Dom3Z family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="2"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060209.1">
        <property type="nucleotide sequence ID" value="XM_003060163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWG0"/>
    <dbReference type="STRING" id="564608.C1MWG0"/>
    <dbReference type="GeneID" id="9685357"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59753"/>
    <dbReference type="eggNOG" id="KOG1982">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MAYWGYS"/>
    <dbReference type="OrthoDB" id="5853397at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034353">
        <property type="term" value="F:mRNA 5'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110155">
        <property type="term" value="P:NAD-cap decapping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013961">
        <property type="entry name" value="RAI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039039">
        <property type="entry name" value="RAI1-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395:SF9">
        <property type="entry name" value="DECAPPING AND EXORIBONUCLEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395">
        <property type="entry name" value="DOM-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08652">
        <property type="entry name" value="RAI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RAI1-like" evidence="4">
        <location>
            <begin position="29"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="397"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="571"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="664"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="452"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="470"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="502"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="595"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="691"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="702"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="714" mass="74962" checksum="D02A7A0AF7477FF5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWK2</accession>
    <name>C1MWK2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59800</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059935.1">
        <property type="nucleotide sequence ID" value="XM_003059889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWK2"/>
    <dbReference type="STRING" id="564608.C1MWK2"/>
    <dbReference type="GeneID" id="9685672"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59800"/>
    <dbReference type="eggNOG" id="KOG2273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KHIEYKV"/>
    <dbReference type="OrthoDB" id="5227681at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="46"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="469" mass="49385" checksum="6E32C8E14DFA4964" modified="2009-05-26" version="1">MTSVDPYPAPGGGGSISDAEVGPAPPPSVEPLSAPAGYDGGDDPSVSLQIEITDPHRAGEGLSKHVEYVVTYWTSGLPKFASASGRVARRYSEFEWLWRALSASADGVLVPALPGKTLSAPLSDDPGSVAIERRRRDLGVFVARIARHPLMRASDDVRTFLEEKDRGAWKERVPWHERGVTSDAIRATQEFFGGAANARASSSSSASSFIDVPNAPNVTNDGIVEDARFVEIGEYVGELKQRVDALLEATTAVTKHHAGAAAAATAFAAACADLDDAELRACANFRAMDGASATVPIRWSAASALFAARAAPSDALADAVADAFREPLRAASALCASATHARDRRRQLVDAYNKLCAEISAIDAKIVALGVPELGSPKRMERDALELRASDARIARTHLGGRYSRAVLVSDRELCWFHGALAASMGDALKAYVASHGAAAGRAARALADAREGLRDATAAPPDAFLPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX28</accession>
    <name>C1MX28_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60008</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060326.1">
        <property type="nucleotide sequence ID" value="XM_003060280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX28"/>
    <dbReference type="STRING" id="564608.C1MX28"/>
    <dbReference type="GeneID" id="9685764"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60008"/>
    <dbReference type="eggNOG" id="KOG0620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TYHMPCA"/>
    <dbReference type="OrthoDB" id="2866996at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF101">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="116"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="446" mass="48912" checksum="98321574C668FC6A" modified="2009-05-26" version="1">MSLTAVASLQPTAFRLLRRVAPRSSSASVRSFASLSAKQGAQTAWISRAHPSRRQSFGFVLAAAAASSRDVSHFSSSVAFAGSRVDRLSHARQHRRAFATSTIVMASSETHDARVVTYNVLSSSLCEPTYFTHCAPEDLDPPTRLKKTLVKLEDEMKKGAVIALQEVSQKWTGELHVFFAKRGYHLVSSLYGKPFNGYMGIALAVPIDKYDVVKVDISRCSDTKRLPRAPKPSKMKELLVDKPLGLYYFLTGKRAKQSDWALARNRFNTIMYATLKCKSSGVEFGVANYHMPCMFRDPRVMTIHSQLAAAYAQKMAGSLPVVLMGDFNLKPGDGGYDLITTGDIDAAHEAAPVAPDGETWSTALTYPMRSAYHVATGSEPDFTNFAQIKDDPQFIDTLDYIFISPTVDVAEVMPLPHRSEVKGPFPSAVEPSDHILLAATVRVPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXE6</accession>
    <name>C1MXE6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 25 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_19208</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060381.1">
        <property type="nucleotide sequence ID" value="XM_003060335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXE6"/>
    <dbReference type="GeneID" id="9686118"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_19208"/>
    <dbReference type="OrthoDB" id="47375at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912226" evidence="1">
        <location>
            <begin position="25"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 25" evidence="2">
        <location>
            <begin position="61"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="304" mass="34103" checksum="C62C74B2EA22E2F6" modified="2009-05-26" version="1" fragment="single">MARARVISALALLFVLAIATVVAADESCDATRGSCAADAAPEESPADVAKLRGLPLVLWLNLDADADRRGHMERMFDRWNVTNHVRVRGHDARRVDVTTLLHGGAAAHPGEIGCTVSHLKALRYFVTRTDEDVALIMEDDADIEQASHWSFAWEEFFDALPVDYDTVQLSLINTQRVHVSLHPRFSNDYGAAAYLVTRHHATKLLRQHVVSDDAVDSDDGVKYRLDNSATGRATSEEILFHAGRGYAVAVFNYRYRGMRTTIHQHEGESLERDHDLIQQRSSKPVREFWEQHGSTTTLSVLMRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXM9</accession>
    <name>C1MXM9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MICPUCDRAFT_47930</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">Belongs to the CDS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060425.1">
        <property type="nucleotide sequence ID" value="XM_003060379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXM9"/>
    <dbReference type="STRING" id="564608.C1MXM9"/>
    <dbReference type="GeneID" id="9686157"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47930"/>
    <dbReference type="eggNOG" id="KOG1440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FRMAQFK"/>
    <dbReference type="OrthoDB" id="10260889at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47101:SF1">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE 4, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47101">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="131"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="291"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEH55194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="435" mass="45101" checksum="B98C7AF3A2A3B66F" modified="2009-05-26" version="1">MATLASLGATSVAPRAAAPRRVANARGVARAPPSRGVARCAKRGESRGDRALARAWDARDGRRARGGERGDAAAARAHAAGARAFEARRHRGSGVAHAAAGAVDGGDASGSTPGVTIVKPKVSAGKLQTRIASALVLGAAGAGVIVAGGVSFALFMSLASFLASKEYFTLASNMSVELPYPPEEWVNTMCVAMCTAFPIILFSCGGKLNVIVQTMMGAYGVTATLLMTKQKDPHFSQFTSVMFGFFYCGFLPSFWVKLRALAWGATASAGAGSTGSAFISAWPAAFGGPGVWTTGLIATIIAVLCIIASDVGAYVVGKTFGKHQLIPLSPNKTIEGAVGGLVSTVGAAFALRWLLGWQAGVVQTTMLGCVIFWSAVAGDLMESVMKRNANMKDSGNIIPGHGGFLDRFDSYLFTGIAVYFFIVTVMPAWFQGVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXP1</accession>
    <name>C1MXP1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60231</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060725.1">
        <property type="nucleotide sequence ID" value="XM_003060679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXP1"/>
    <dbReference type="GeneID" id="9685870"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60231"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="271" mass="30951" checksum="AFA797B0E4A66AF4" modified="2009-05-26" version="1">MGRRREGNENAIIGMWRRLDVSLVYERDSTGPARIMGDPTRNRERAVYTSNVLTFAFPRVIFPSPSPPTLPPRLFSRSHQVYCSPEHKVGHVFSLVARKEQPPSCALTHCLKARFLPCGFCLAINMYNWIAVVAGREHEINNELYELPIGEFAKSNFIRIKFKADFYQCITCPCAWPFVVFNKAVLCKCNPWKHYDHLNYDKPRWSDNDGRVSAGRYITPGNFFKTPSMKAPAKGDDPIEKISALKKLYDADAIDKEEYETAKAALLKQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY53</accession>
    <name>C1MY53_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60405</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060508.1">
        <property type="nucleotide sequence ID" value="XM_003060462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY53"/>
    <dbReference type="GeneID" id="9685946"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60405"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF31">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="334" mass="36105" checksum="FF1F7BFC9E0EE82B" modified="2009-05-26" version="1">MILDPSLPTPSTASVFIRPRAVVVNLGALYTPVPIRPRRRGERRSLRTFPGASLRPALALSPRPPRRLSTPLLTPFNSPPTSLCMERPSEHVKMIVVSTHALLFTSAEPDAHVRRFVALLKRQLAPPGAGGGGEECGSPREGQTPAWTPSGGARRTRSEPAPETLTRPPTRSPSKPTPFAPVPAPQPPPSRTSTPPPLSRMYSLESGMDDILDAAKCAEYDAAAAAAAAAAAAADDDDDLDDSRTFPTTDILGLKHDIAHDLRVLDLPFELRVIEAALHDVCQRLLDETTMLERDASPALERLADHVTRRSLERVRSVKARPPHTGPHTTPSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYC5</accession>
    <name>C1MYC5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="21">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">MICPUCDRAFT_18963</name>
    </gene>
    <organism evidence="23">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 21">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="21"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060259.1">
        <property type="nucleotide sequence ID" value="XM_003060213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYC5"/>
    <dbReference type="STRING" id="564608.C1MYC5"/>
    <dbReference type="GeneID" id="9685990"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18963"/>
    <dbReference type="eggNOG" id="KOG2204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WRMFKNI"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009100">
        <property type="term" value="P:glycoprotein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000017">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF6">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE IA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 20" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="15 21" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 21 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="448"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="534"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="20">
        <location>
            <begin position="372"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EEH55028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="555" mass="62180" checksum="AB95036CB23F7CE5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYC6</accession>
    <name>C1MYC6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GCY</name>
        <name evidence="10" type="ORF">MICPUCDRAFT_59862</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060552.1">
        <property type="nucleotide sequence ID" value="XM_003060506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYC6"/>
    <dbReference type="STRING" id="564608.C1MYC6"/>
    <dbReference type="GeneID" id="9685715"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59862"/>
    <dbReference type="eggNOG" id="KOG1023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAIMPPP"/>
    <dbReference type="OrthoDB" id="532905at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="9">
        <location>
            <begin position="464"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="277"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="391"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="694"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="424"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="700"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="727"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH55321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="752" mass="81478" checksum="6478CEF66C3D5B18" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYN3</accession>
    <name>C1MYN3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_59964</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat EDC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060598.1">
        <property type="nucleotide sequence ID" value="XM_003060552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYN3"/>
    <dbReference type="STRING" id="564608.C1MYN3"/>
    <dbReference type="GeneID" id="9685743"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59964"/>
    <dbReference type="eggNOG" id="KOG1916">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TREHMGT"/>
    <dbReference type="OrthoDB" id="21128at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.100:FF:000001">
        <property type="entry name" value="Enhancer of mRNA-decapping protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.100">
        <property type="entry name" value="conserved c-terminal region of ge- 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045152">
        <property type="entry name" value="EDC4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049404">
        <property type="entry name" value="EDC4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044938">
        <property type="entry name" value="EDC4_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032401">
        <property type="entry name" value="EDC4_WD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598:SF5">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21289">
        <property type="entry name" value="EDC4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16529">
        <property type="entry name" value="Ge1_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Enhancer of mRNA-decapping protein 4 WD40 repeat region" evidence="8">
        <location>
            <begin position="71"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Enhancer of mRNA-decapping protein 4 C-terminal" evidence="9">
        <location>
            <begin position="779"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="423"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="545"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH55367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="912" mass="94482" checksum="4C124C038D73E927" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ49</accession>
    <name>C1MZ49_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_60602</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060895.1">
        <property type="nucleotide sequence ID" value="XM_003060849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ49"/>
    <dbReference type="GeneID" id="9686593"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60602"/>
    <dbReference type="eggNOG" id="KOG1605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1872">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ATSMSWI"/>
    <dbReference type="OrthoDB" id="1711508at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090364">
        <property type="term" value="P:regulation of proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011943">
        <property type="entry name" value="HAD-SF_hydro_IIID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051658">
        <property type="entry name" value="UBLCP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02245">
        <property type="entry name" value="HAD_IIID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="4">
        <location>
            <begin position="134"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="319" mass="36536" checksum="6F393A6E0BA0A9BF" modified="2009-05-26" version="1">MTNASTTIAVKWQGKQFTVTVPEEADVACLKRCIEAETNVQPKRQKLLNVKQGPKPAADDAALASLKMPKVVMCMGSTEASINEVVVAAEQAPEVVDDFDVGVDEKIDVRDKEENVEKLRRRIEKYKVEPLNPPRDGKKLLVLDIDYTLFDHRSTAEAPHELMRPYLHEFLTAAYEHYDIAIWSATGMKWIEVKMKELGVLNNPNYKLLQLVDHGAMITVHTEKYGVFDCKPLGWLWAKFDGRYGEHNTIMFDDLRRNFVMNPKNGLKIRPFRKAHMNMATDVELRELTKYLLAIAPLPDFGVLRHSRWESYIADSTYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZA6</accession>
    <name>C1MZA6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60662</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060925.1">
        <property type="nucleotide sequence ID" value="XM_003060879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZA6"/>
    <dbReference type="GeneID" id="9686364"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60662"/>
    <dbReference type="eggNOG" id="ENOG502QTIQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2017234at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47489">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASES (NAT) SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47489:SF2">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="77"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="287" mass="30426" checksum="C54209579A45548C" modified="2009-05-26" version="1">MAAVARAAPPAARARAGGASRRRRADEDASRLRPRGRPPRLRAFTDAVGSVERRHDLLLAQAAFKRARLPLANDDVATVRPMRAADVRALTEVMSGAFKGTPDERPRARVAKYLLDQLEPNPEEICLVAVLGDDDDDDDARGEEDGDASPRATATPVAIASLSFTARARGDPANGGARSDAGAGSLPVPTDAPYLCNMAVDAAHRRKGLARALLSACDDLVVEMGGADVWLHVRANDAAATALYESAGYDEMKRESAMRRFFSADGGGVVLMRKELVPGGVNAIFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZD8</accession>
    <name>C1MZD8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_41290</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060940.1">
        <property type="nucleotide sequence ID" value="XM_003060894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZD8"/>
    <dbReference type="GeneID" id="9686637"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41290"/>
    <dbReference type="OMA" id="TTVEGWK"/>
    <dbReference type="OrthoDB" id="10481346at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="251" mass="26508" checksum="D6CFB089C095B4A8" modified="2009-05-26" version="1">MVSATLSTKTEIKGFKSPTAKLATFEIESSATVAGWKLVAVAAPSTPALSKSGIAKPSSSEVELNAEASKDGLTIFFDNLQLLPKRQFGPRVKSSTKHALGSGGYKVGVDATFIARGNTSEGKAKTPAPTEVLKLTLKPDSIRGFTPKMDYSTAKNVAALEVKTNVDRFLVTMKGEYDLKSKALGNASASASTTVKLPEDVKAKIEVKSDASGKVELMKGTLTVDVPIKKGFKPPSVDDIALKIKFEQSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZE8</accession>
    <name>C1MZE8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_60706</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dpy-30 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060945.1">
        <property type="nucleotide sequence ID" value="XM_003060899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZE8"/>
    <dbReference type="STRING" id="564608.C1MZE8"/>
    <dbReference type="GeneID" id="9686642"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60706"/>
    <dbReference type="eggNOG" id="KOG4109">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GCDENNA"/>
    <dbReference type="OrthoDB" id="417678at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22965">
        <property type="entry name" value="DD_DPY30_SDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007858">
        <property type="entry name" value="Dpy-30_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049629">
        <property type="entry name" value="DPY30_SDC1_DD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05186">
        <property type="entry name" value="Dpy-30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="123" mass="12806" checksum="E3337AA72268EE48" modified="2009-05-26" version="1">MSEETPPDVPAEEAPPAEEAAPAEEAAPAEEAAPAEEAAPAEEEPPAEEEAPAAEEAPAAAEPAAPVAAAAVPARKGPPVRQYLDETVVPVLRQGLRELVKARPADPFEFLGDYIKKANPNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZU4</accession>
    <name>C1MZU4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_8690</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061013.1">
        <property type="nucleotide sequence ID" value="XM_003060967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZU4"/>
    <dbReference type="STRING" id="564608.C1MZU4"/>
    <dbReference type="GeneID" id="9686720"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8690"/>
    <dbReference type="eggNOG" id="KOG2532">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IDCERRT"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF446">
        <property type="entry name" value="SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="140" mass="14165" checksum="AF05BF8C58DEF329" modified="2009-05-26" version="1" fragment="single">LTAFTCGATGVASDALLKNGAERWKVRRLMMNIATIGPCVALLLLPLAKSATIAVALLGVMLGSQAVAIGGYLAYMQDVAPARAGAFLGVTNTVGVAAGIAANVLTGFLVERTGGFDAVFLVTAGVYASSAMVWNAFLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZV7</accession>
    <name>C1MZV7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyribodipyrimidine photo-lyase</fullName>
            <ecNumber evidence="3">4.1.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DNA photolyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_10493</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA).</text>
            <dbReference type="EC" id="4.1.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-2 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.3" evidence="3"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061022.1">
        <property type="nucleotide sequence ID" value="XM_003060976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZV7"/>
    <dbReference type="STRING" id="564608.C1MZV7"/>
    <dbReference type="GeneID" id="9686461"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_10493"/>
    <dbReference type="eggNOG" id="KOG0133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GMHDRAH"/>
    <dbReference type="OrthoDB" id="494480at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000719">
        <property type="term" value="P:photoreactive repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.579.10:FF:000002">
        <property type="entry name" value="Deoxyribodipyrimidine photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000110">
        <property type="entry name" value="Deoxyribodipyrimidine photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008148">
        <property type="entry name" value="DNA_photolyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032673">
        <property type="entry name" value="DNA_photolyase_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052219">
        <property type="entry name" value="Photolyase_Class-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00591">
        <property type="entry name" value="phr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211:SF0">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTO-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTOLYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01084">
        <property type="entry name" value="DNA_PHOTOLYASES_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="14">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH54672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="457" mass="50978" checksum="6025D9937A50433F" modified="2009-05-26" version="1" fragment="single">WCSRDQRVDDNWALLHALSVAKSRNVPVAIVFVLVPSFASASARQYAFMLRGLREMAKTCEATRLPFHLVRGDANPAAAAAAAATRLDASLVVTDFSPLRAPREWRNDLSDALKRANVTVHEVDAHNVVPVWEASNKREYAARTIRPRITKRLAAFLTSFPTRDAVRDAALAAAASPRATDVPTPERVDWDALIADARGRDGGVVPETLHPTRRKPPGEAAARRALVGGPDAFLPSRLAMYDKRNDPNVPRALSGLSPYLHFGQLSAQRVALETNAARTEATAAAADAFVEEVVVRSELSDNYCFHEPNYDNINGASGWAIESLRLHAEDARDPAYSLEELESGSTRDELWNAAQLEMVHFGAMHGFLRMYWAKKILEWTAEGPEVALERAIYLNDKYQLDGRDSNGYVGCMWAICGVHDNAWKERDVFGKIRYMNYNGCKRKFKIDEYVERIEREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0D1</accession>
    <name>C1N0D1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Thioredoxin peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thioredoxin-dependent peroxiredoxin Q</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_20403</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061613.1">
        <property type="nucleotide sequence ID" value="XM_003061567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0D1"/>
    <dbReference type="STRING" id="564608.C1N0D1"/>
    <dbReference type="GeneID" id="9686814"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20403"/>
    <dbReference type="eggNOG" id="KOG0855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PKKFMGK"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF4">
        <property type="entry name" value="AHPC_TSA FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912292" description="thioredoxin-dependent peroxiredoxin" evidence="12">
        <location>
            <begin position="29"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="13">
        <location>
            <begin position="30"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH54243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="187" mass="19833" checksum="0E955B8479A0B573" modified="2009-05-26" version="1" fragment="single">SRRGALLSAVAVSSAIATFFSSPPDAYALGDVGSAAPKFTLPATGGGTVALEDVLKANKYTVLYFYNQDFSQGCSIEAERFNQALPDFAKKGAEVVGVSMDNMEKHEEFCTAKGLGFKLLSDGDGSVSASYGADLKIPILGKFSDRQTFLIDASGTIKGHWLERDGSMGNVKTPAHTQQILEAIDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1A3</accession>
    <name>C1N1A3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Histone-lysine N-methyltransferase, H3 lysine-79 specific</fullName>
            <ecNumber evidence="1 6">2.1.1.360</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 6">Histone H3-K79 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_51323</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60328"/>
            <dbReference type="Rhea" id="RHEA-COMP:15549"/>
            <dbReference type="Rhea" id="RHEA-COMP:15552"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.360"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.360" evidence="1 6"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061777.1">
        <property type="nucleotide sequence ID" value="XM_003061731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1A3"/>
    <dbReference type="STRING" id="564608.C1N1A3"/>
    <dbReference type="GeneID" id="9686973"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51323"/>
    <dbReference type="eggNOG" id="ENOG502S97D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LTHAAWW"/>
    <dbReference type="OrthoDB" id="443402at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140956">
        <property type="term" value="F:histone H3K79 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025789">
        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030445">
        <property type="entry name" value="H3-K79_meTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451:SF19">
        <property type="entry name" value="ACTIVATED IN BLOCKED UNFOLDED PROTEIN RESPONSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451">
        <property type="entry name" value="HISTONE H3 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08123">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51569">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DOT1" evidence="7">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU271113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="225" mass="24817" checksum="97B72B02A48AEF74" modified="2009-05-26" version="1">MSLPVKDTTNAPREVDAFEDRRALYDTAYENLGRDVGLEIAERSHDGCARVPGDGWFYGELSWEGMWDVVALAEPKPGDIFLDLGSGLGKMVVAQSLTRDFAECWGVEILPELHDAAMDAPGKLRAAMGDDAFDALPEVDLRRGDMLAADVSDADVIYCYATVFAAQVVSRLQAKLAAEMKPGARLVMISKQMESPEFDAFGVGYFSVPQAHSRWNMDAWLYVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1B7</accession>
    <name>C1N1B7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">16S rRNA (uracil(1498)-N(3))-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_20469</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>uridine(1498) in 16S rRNA + S-adenosyl-L-methionine = N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="3"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061784.1">
        <property type="nucleotide sequence ID" value="XM_003061738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1B7"/>
    <dbReference type="STRING" id="564608.C1N1B7"/>
    <dbReference type="GeneID" id="9687223"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_20469"/>
    <dbReference type="eggNOG" id="ENOG502QPPV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ERWQRIS"/>
    <dbReference type="OrthoDB" id="3465at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18084">
        <property type="entry name" value="RsmE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="RsmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046886">
        <property type="entry name" value="RsmE_MTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027:SF3">
        <property type="entry name" value="16S RRNA (URACIL(1498)-N(3))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA small subunit methyltransferase E methyltransferase" evidence="12">
        <location>
            <begin position="3"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="101"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH54414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="184" mass="18848" checksum="503E1F0C8C5B75F6" modified="2009-05-26" version="1" fragment="single">RWEVAVACGGLKGGRADWLVEKLAELGAASLAPTLTARSAVTKRGREGRWVRVAAAASKQCLRTHALVVESPCAFDALLRRVRDAPIALLAAAGAPPLRDALRDADVDDGDDGETASGPGRGATGGLLIVGPEGDFTEDELGALIDAGATPVGLGPLRLRVETAAVALMACVGMMHPRKPPPGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1J1</accession>
    <name>C1N1J1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="11">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">DLDH-GCSL</name>
        <name evidence="14" type="ORF">MICPUCDRAFT_28757</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9 11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="11"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061831.1">
        <property type="nucleotide sequence ID" value="XM_003061785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1J1"/>
    <dbReference type="STRING" id="564608.C1N1J1"/>
    <dbReference type="GeneID" id="9687007"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_28757"/>
    <dbReference type="eggNOG" id="KOG1335">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAQLGMK"/>
    <dbReference type="OrthoDB" id="361797at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050151">
        <property type="entry name" value="Class-I_Pyr_Nuc-Dis_Oxidored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912:SF223">
        <property type="entry name" value="DIHYDROLIPOYL DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912">
        <property type="entry name" value="DISULFIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="2 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9 11" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="13">
        <location>
            <begin position="38"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="12">
        <location>
            <begin position="384"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="482"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="178"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="215"/>
            <end position="222"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="356"/>
            <end position="359"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="10">
        <location>
            <begin position="75"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH54461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="503" mass="52369" checksum="56962B480BA667D7" modified="2009-05-26" version="1">MLPALARRLPALAPLARANANALFLRSFAADAGGDVQDVVVIGGGPGGYVAAIKGAQLGMKVTCVEGRGTLGGTCLNVGCIPSKALLHASHLFHDANHTMAKHGITVGEVSIDVGKMMAQKSKSVEGLTKGIEGLFKKNKVTYVKGWGSLTSKPGEVSVAAADGTTVTINAKNVILATGSEPASLPGVDVDEKQVVTSTGALDLAEVPKRMVVIGGGVIGLELGSVWSRLGSAVTVVEFGKDICPPMDGQVRKTFQRALKKQGFDFKMQKKVTAAKKQKDGSILLTVEPSAGGEAEFLEADVVLVSTGRKPYTTNLGLADAGVEVNGKGQVVVDMHTYKTNKDGVYAIGDIVEGPMLAHKAEEEGISCVEQLAGKSGHVNYDVIPSIVYTHPEVAWCGKTEEELKAAGTEYNVGTFPFAANSRARTNDDSEGLVKFVSCKHTDKILGAHIVGPAAGELLAECVLAMEYGASTEDIARTCHGHPTLSEAVKEAALATGGKAIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1M2</accession>
    <name>C1N1M2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48334</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061582.1">
        <property type="nucleotide sequence ID" value="XM_003061536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1M2"/>
    <dbReference type="GeneID" id="9687286"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48334"/>
    <dbReference type="OMA" id="YERFEAM"/>
    <dbReference type="OrthoDB" id="10651795at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="636"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="659" mass="70556" checksum="7DAD0CC680FA7FCA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1N9</accession>
    <name>C1N1N9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51676</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061947.1">
        <property type="nucleotide sequence ID" value="XM_003061901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1N9"/>
    <dbReference type="GeneID" id="9687590"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51676"/>
    <dbReference type="OMA" id="KIWENAP"/>
    <dbReference type="OrthoDB" id="495453at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="378" mass="38422" checksum="81BF8AE3E7FEF5C2" modified="2009-05-26" version="1">MSAAATASGPRAAAAPRACATSHRGRGATPWTIATARATRVVPRAPRSVEETDRVVVVVVEEAREARETREADDDADDAEAARPASSAADETAVASASASASASADARAWAVGLAAAVGVGVASLAIDPSSFPRAPSSPPSSPPSWSWSSSSSRGARVQATTPTTGHPAGATCGTFSAARTAVARDVLTCNQDNWEAGCLSHYSEDVTYVDGPGLTNVRGKDAMARYLKNQFDFSRQYLTVSDETCVGDTYVARWSLDMDLGTGNLRGMPGISVLKFATETDEDAAGEGGGAEGAEGAEGGGGGSGGGASDAARATAAGAGGATGDRNAVRYHRDYLPDGKIWENAPVVGPLVKFQRATYTACMLSESGCADLLGAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1V1</accession>
    <name>C1N1V1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48421</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061978.1">
        <property type="nucleotide sequence ID" value="XM_003061932.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9687621"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48421"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="572"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="818"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="988"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1052"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1100"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1161"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1198"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1230"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1349"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1919"/>
            <end position="1939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2139"/>
            <end position="2208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2250"/>
            <end position="2273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2294"/>
            <end position="2331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2353"/>
            <end position="2391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="144"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="443"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="713"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1268"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1376"/>
            <end position="1425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1469"/>
            <end position="1543"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1572"/>
            <end position="1599"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1715"/>
            <end position="1874"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1963"/>
            <end position="2060"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2085"/>
            <end position="2112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="352"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="572"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="606"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="630"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="827"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="988"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1063"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1231"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1357"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1923"/>
            <end position="1932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2147"/>
            <end position="2161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2198"/>
            <end position="2207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2255"/>
            <end position="2266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2299"/>
            <end position="2331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="2391" mass="258653" checksum="51BCD7075311D6FF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N238</accession>
    <name>C1N238_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51838</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062225.1">
        <property type="nucleotide sequence ID" value="XM_003062179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N238"/>
    <dbReference type="GeneID" id="9687462"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51838"/>
    <dbReference type="OrthoDB" id="498062at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="150" mass="15928" checksum="E33A9D50E7EFC38C" modified="2009-05-26" version="1">MLATTTTPFASRATRTSSKTAARVVASARRSSTASSPSPSSLPKIVANASPFLPRASGRDETGDPSPSSSQQQRGGEDEPDRDEDGLYIGTYSNFFTDPDQIKGVIIFCAFLASFLSLGNIGAAILLPILYDQPIQTCIQGILFGYYCPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N256</accession>
    <name>C1N256_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51856</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062232.1">
        <property type="nucleotide sequence ID" value="XM_003062186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N256"/>
    <dbReference type="STRING" id="564608.C1N256"/>
    <dbReference type="GeneID" id="9687473"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51856"/>
    <dbReference type="eggNOG" id="ENOG502SBK5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="18"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="265" mass="29314" checksum="6F41C2C31EFB39E9" modified="2009-05-26" version="1">MTTPQTSDLVAVEFAQMYRELREARAALAKRDAELEDSRAKRAKLVSELDATRAEFEVLRALHPTKIDGAIACVIFAHLEDPKDRVALAAVSKVFRDAEQSDASLPGSTEALRELGDKFCKDHYMKASYWFRKAADRGDADAMFKMGSFYAVECGVMTDLSTACEWWERASGCGQLNATFELADCCEAGVGVERNGAKALELYLKGAELGCKTCPMRLGRIYEHGDCGVAVNKTEALKWYRVSVERGDDYAELWVVRLEAELAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2F3</accession>
    <name>C1N2F3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_48349</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061863.1">
        <property type="nucleotide sequence ID" value="XM_003061817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2F3"/>
    <dbReference type="STRING" id="564608.C1N2F3"/>
    <dbReference type="GeneID" id="9687517"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48349"/>
    <dbReference type="eggNOG" id="ENOG502QQ2I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CITTRRV"/>
    <dbReference type="OrthoDB" id="250836at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051767">
        <property type="entry name" value="Nucleoporin_NUP42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527:SF1">
        <property type="entry name" value="NUCLEOPORIN NUP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527">
        <property type="entry name" value="NUCLEOPORIN-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="267"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="297"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="369"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="379" mass="36277" checksum="4ECD0CEC8B34755E" modified="2009-05-26" version="1">MGGNRRGGGGRGRGRGGGGGGGNGNNNYGGGGNSFAALSDHRGGGGGFHDHGARGGGGGGFGGGGGFGGGGGGGGGRGGGGGGRGGGGRGGGGRGGGGRGGGGRGGGGRGDDPSLNALRDDLQTDRAMMWPLSCYGKGDERCLLGGDTSFEELRWVVGAVALARGDANAVHARAREFARGKEDDVNAILGFPPRQLKTVLENAAAGRMAPAGASRVIDCSMLLGMATTPAGMATPGPGMMGPGMPTPPGGIMTPGTVPGGFVGGGIPPTPAPPSPATPGGFGFLQQQQPQQQPQPHMGGGVGGQRLGQLGGFPDAPAPGGGGFGGGGGFAPTPTPPTPGGAGSQTSPPGADAGNNPWAMRRWAVGEIPDAPPPQQYIQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2Q7</accession>
    <name>C1N2Q7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_41868</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062128.1">
        <property type="nucleotide sequence ID" value="XM_003062082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2Q7"/>
    <dbReference type="STRING" id="564608.C1N2Q7"/>
    <dbReference type="GeneID" id="9687567"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41868"/>
    <dbReference type="eggNOG" id="KOG0235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="354304at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF44">
        <property type="entry name" value="PHOSPHATASE C1620.13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="103"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="16"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="274" mass="29060" checksum="9CC46C2F542AE387" modified="2009-05-26" version="1">MRAREGHDVVEFVIVRHGQTTWNASGTIQGQADAPLDELGIAQARVTAAEIARGVRWGHVDSVDSSDLRRAADTASVIAASSSSASSSSSAVRAHAALRERHAGSLQGIRRADAPARDPKAWKALRGGDDATRVPGGGESYDDVLDRVVPWFEDEARARARARAAAAGEGGGRGGGRGVVVTHGGVIHVLSDRCEADDEWFDDDDDRDDVRRGRGRVVVKNCAVGVLRLHVPREDDAAGERRVRWRIGETWGDASHLEEGGLRSSAWGGGAAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1N357</accession>
    <name>C1N357_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein arginine methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_42120</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062551.1">
        <property type="nucleotide sequence ID" value="XM_003062505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N357"/>
    <dbReference type="STRING" id="564608.C1N357"/>
    <dbReference type="GeneID" id="9687762"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42120"/>
    <dbReference type="eggNOG" id="KOG1501">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YRWHPQA"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF4">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="6">
        <location>
            <begin position="735"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="347"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="414"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="914" mass="100607" checksum="1F47121DE95161AE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3I3</accession>
    <name>C1N3I3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cilia- and flagella-associated protein 300</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_52185</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CFAP300 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062617.1">
        <property type="nucleotide sequence ID" value="XM_003062571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3I3"/>
    <dbReference type="STRING" id="564608.C1N3I3"/>
    <dbReference type="GeneID" id="9688057"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52185"/>
    <dbReference type="OMA" id="FYHCYGV"/>
    <dbReference type="OrthoDB" id="567861at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029416">
        <property type="entry name" value="CFAP300"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31078">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31078:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14926">
        <property type="entry name" value="CFAP300"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH53436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="351" mass="38977" checksum="836F17FA4461D07D" modified="2009-05-26" version="1">MANDDDDGVADATVFAKLPDLAAGAFAEDPSRSRLVKWNLAPNTHVVRFRYTKPFHKMDPQGFLRDFFSSERVREHFVVIDASGARRTLAELGLDRARGGRCVDVKFAPTPCAATSMAHFDALESQDAPNPIVRAGTEYIHKCIDDVVRGFPVCDLLRDFLLRGDESENASLWSDAQRDEFIARVFRRVLFSSHWTFAFVSLRPPLAFNTRLRYLSTPPLTPFDAAPTLFAFSRGRSTLRHLVIGGSMCQYEDTLGAYLETTKAVYKTLVRARKDASSGGNGGEGEPAAVVATDVYEVTGASFASDVGAEAGEGTSLALFPRISEQNWCYLCVDARRRHATVWYHAFVPYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3M2</accession>
    <name>C1N3M2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_52226</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062640.1">
        <property type="nucleotide sequence ID" value="XM_003062594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3M2"/>
    <dbReference type="GeneID" id="9687838"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52226"/>
    <dbReference type="OrthoDB" id="66964at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="131" mass="14254" checksum="B2BB5317DD7596C1" modified="2009-05-26" version="1">MPPRPLGCLPQEIVLEVFGCAGVSRLVEVEARPRVGAVGAAFAKPGRWSRVLKFAMKDAEISRLAVAKNLTPMTSYTFRCRAGVTTADLGPEWSGEAGRLVPEIYGPWSDEVRSSIHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3P5</accession>
    <name>C1N3P5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_52252</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062410.1">
        <property type="nucleotide sequence ID" value="XM_003062364.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N3P5"/>
    <dbReference type="GeneID" id="9688091"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52252"/>
    <dbReference type="eggNOG" id="KOG1124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AWAVMES"/>
    <dbReference type="OrthoDB" id="427950at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21262:SF12">
        <property type="entry name" value="GTP DIPHOSPHOKINASE CRSH, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21262">
        <property type="entry name" value="GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13328">
        <property type="entry name" value="HD_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="679"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="733"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="1245"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="186"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="523"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1003"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1390"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1461"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="95"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="194"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="549"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="580"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1009"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1023"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1476"/>
            <end position="1516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH53229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1570" mass="164673" checksum="C7D14F98BD4B02C1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3Y3</accession>
    <name>C1N3Y3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_52340</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062454.1">
        <property type="nucleotide sequence ID" value="XM_003062408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3Y3"/>
    <dbReference type="GeneID" id="9688135"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52340"/>
    <dbReference type="eggNOG" id="KOG4332">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MNTWPEN"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17487">
        <property type="entry name" value="MFS_MFSD5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="357"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH53273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="453" mass="49952" checksum="832942EDFA015D7B" modified="2009-05-26" version="1">MEGYYWLQFGILAIACAGLEMQKAGNKERVAMPDTFISFRNLYLFVYSLMMAGDWLQGPYVYALYQHYGYSTGDIGKLFIAGFGSSMIFGTVVGSMADKYGRKNAALTYCVTYIASCVTKHWSDYNVLMLGRFFGGIATSLLFTSFESWLVAEHFKRGYEAEWLDKTFAKAIFLGNGLVSIVSGLLANFLVTDMNMGPVAPFDAAACFLAIGGVVILFTWSENKGDASESTTVQQGMQQAYAAIASDKRVFYLGAMQSLFEASMYSFVFLWTPALGPNGEDIPHGMIFATMMVACMVGSSVASRIMSRPDTRPEKYMQTVFLASAASLSIPVLTRSLGMESDGYKGGPITFEGKVQMLGFLVFEAMVGIFWPSMMKMRSQYVPEEVRSTVMNFFRIPLNLFVCVILYNVAMFPLAAMFAMCTLFLLIAAALQKKLEQLTEGPVYKKAAGMGPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N444</accession>
    <name>C1N444_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_52404</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062480.1">
        <property type="nucleotide sequence ID" value="XM_003062434.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N444"/>
    <dbReference type="GeneID" id="9688170"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52404"/>
    <dbReference type="eggNOG" id="ENOG502SE28">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SKEECAN"/>
    <dbReference type="OrthoDB" id="10379006at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013253">
        <property type="entry name" value="Spc7_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08317">
        <property type="entry name" value="Spc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spc7 kinetochore protein" evidence="3">
        <location>
            <begin position="1052"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="669"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="729"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="797"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="955"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1251"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="955"/>
            <end position="964"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1676" mass="170538" checksum="4D6E7A6F0B42C82F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4D4</accession>
    <name>C1N4D4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_36043</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062770.1">
        <property type="nucleotide sequence ID" value="XM_003062724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4D4"/>
    <dbReference type="GeneID" id="9688210"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36043"/>
    <dbReference type="eggNOG" id="KOG1581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KIMTQHY"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF13">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="327"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="365" mass="39180" checksum="85073AA8DFA6213E" modified="2009-05-26" version="1">MSGVAQGAPAYDAAMILKVVGCVVGVVGSLLVYGILQERIMTKPYDDGGSEESFTFSVFLVMNNRIVSMAVAVATLAWMRGAVQPVAPMYKYAAVSASNVVATTCQYEALKYVSFPVQTLGKCAKMIPVMIWGYAINGKSYKLQDYAIAVGVMLGCAVFATYGPTTSKKHGKTAAETGAYGVALMLGYLGFDGFTSTFQDKLFRGYQMETYNQMLWVNACSAAVSCLWLFGDASMGAAIAFIQRHPAALVDCFTLSLASTCGQLCILYTIREFGALLFATIMTTRQFLSILLSCLIFMHPLTWQQWLGTALVFASLYYQAFNKGARGGKSGEVGGGGGDGGDAKDPLAKEMHAEQRERFAGSNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4G6</accession>
    <name>C1N4G6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52549</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062996.1">
        <property type="nucleotide sequence ID" value="XM_003062950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4G6"/>
    <dbReference type="GeneID" id="9688226"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52549"/>
    <dbReference type="OMA" id="AMRITSH"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="469"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="797" mass="82296" checksum="8BF9204D9DBD3280" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5A7</accession>
    <name>C1N5A7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">AMT1.1</name>
        <name evidence="10" type="ORF">MICPUCDRAFT_29536</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062934.1">
        <property type="nucleotide sequence ID" value="XM_003062888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5A7"/>
    <dbReference type="STRING" id="564608.C1N5A7"/>
    <dbReference type="GeneID" id="9688374"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_29536"/>
    <dbReference type="eggNOG" id="KOG0682">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAGSDVM"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097272">
        <property type="term" value="P:ammonium homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000008">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730:SF6">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="56"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="477" mass="49920" checksum="891F8A9CF59D648F" modified="2009-05-26" version="1">MASWCTAADKAALAASGLAEAAVSVICAGDARRRLDSDTEDDYTKMGIANATTTIFLLFATALVFFMQSGFAMLCAGSIRAKNVKNILLKNVLDAAVGAIFWYLFGYGIAFGVPGDGNSNRFMGEADFALGISAVGPSGGNDWIWFLFQWSFAAAAATITSGAMAERTQFAAYLGYSALLTGFVYPTVVHWAWGGGWLSSVPWKKEDGDKSLAYHDFAGSGVVHMVGGFSGLMGAIMVGPRTGRFDAQGRPIAMPGHNAALVVLGTFILWVGWYGFNCGSQGSATSAADAVAIGRVGITTTLAASAGGVTSLFLNYALYKVWDLIAVCNGVLGGLVSITAGCAVLDIYMALFAGFIGAFVLFGSSKLLLKLRIDDPLEAFPVHGACGMWGVLAVGLFAKEKYLGDEDNDRYGALMGGNGRLFGVQLLGCVAIILWTCGILGPFFFVLKQAGLLRTSAEEEAAGLDESKHGGSAYNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5J4</accession>
    <name>C1N5J4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52944</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063374.1">
        <property type="nucleotide sequence ID" value="XM_003063328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5J4"/>
    <dbReference type="GeneID" id="9688813"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52944"/>
    <dbReference type="OMA" id="PEREQPD"/>
    <dbReference type="OrthoDB" id="552969at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1100.10">
        <property type="entry name" value="Transcription factor, SBP-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004333">
        <property type="entry name" value="SBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036893">
        <property type="entry name" value="SBP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03110">
        <property type="entry name" value="SBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103612">
        <property type="entry name" value="SBT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51141">
        <property type="entry name" value="ZF_SBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP-type" evidence="2">
        <location>
            <begin position="170"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="476" mass="47048" checksum="95F5ADAF1CBC0D91" modified="2009-05-26" version="1">MTRNEPAEDAGAIATTTARGIASDTQRVGLTANAANASEAPISAEDLATAAELFGLRHAQEAPTGEGEREAASGVAHARADATIETDTPPSTEANAPAPKATTTRETSGKEGGELAATSASLGHSSGATTASLATTSEATGITNATNATTTTGGTARRGGHGRAHPVKFKGCCLVDNCENPRKQMLQRARMYLTCAEHARAKMVMFKDEECRECQACRTFHPLSEFDGLNKTCETRLSRKKVRYRARTQSGAVSGGTVGSGGMPPLSGAGSVGAGGGGNAAKRPRVGGYNDGDHTATTPGAALAESPLYWPPYGGAPGGLGTFPGSGPPVSSDAAWIIAEASAEAFRAAVQRSVANAMGAGAGGAGAAPGSVGGGNGLPGGAHAMGALPGGVHGLPCILGGAPATDALAGIPGGAHGSAVMNLEWMRVNQLLGMAQQFQAQQGAEGSNGVFPPAPPGPDVGSGGNGSAGAPGCCVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5N6</accession>
    <name>C1N5N6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63722</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063188.1">
        <property type="nucleotide sequence ID" value="XM_003063142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5N6"/>
    <dbReference type="GeneID" id="9688835"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63722"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="682"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="727"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="836" mass="86291" checksum="0BC2934B52CE18A9" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5V1</accession>
    <name>C1N5V1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_11887</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the histone H2A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063220.1">
        <property type="nucleotide sequence ID" value="XM_003063174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5V1"/>
    <dbReference type="STRING" id="564608.C1N5V1"/>
    <dbReference type="GeneID" id="9688868"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11887"/>
    <dbReference type="eggNOG" id="KOG1756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NYCERIG"/>
    <dbReference type="OrthoDB" id="496320at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000009">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="11">
        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="12">
        <location>
            <begin position="90"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH52356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="124" mass="13018" checksum="5B80D962027B8E05" modified="2009-05-26" version="1" fragment="single">MSGRGKGKSGKKAVSRSAKAGLQFPVGRIARYLKIGKYATRVGAGAPVYLAAVLEYLAAEVLELAGNASRDNKKSRIVPRHIQLAIRNDEELSKLLGTVTIASGGVLPNIHSVLLPKKGKGKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N611</accession>
    <name>C1N611_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_53118</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063252.1">
        <property type="nucleotide sequence ID" value="XM_003063206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N611"/>
    <dbReference type="GeneID" id="9688692"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53118"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="102" mass="11224" checksum="7888DC4744D742E8" modified="2009-05-26" version="1">MWDDLIAVCVETPGATRKLLDAIGRGDARGADPRRVVERLPAGAVVAGARAALAEVLGARRVEAEAWRRRREEMEGIARRALREREEVGRRAYDPAKVSFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6L0</accession>
    <name>C1N6L0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_11321</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063566.1">
        <property type="nucleotide sequence ID" value="XM_003063520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6L0"/>
    <dbReference type="STRING" id="564608.C1N6L0"/>
    <dbReference type="GeneID" id="9689007"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11321"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="514228at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="3">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="264" mass="26731" checksum="D274556EC91C261F" modified="2009-05-26" version="1" fragment="single">EAMHLDPRQRVLVADVSAAWTAAATTTAKQRTNDVAVFTGVAGKDYALLLKSCGVQIGTFTGTGNEASVTCGRVMFSLGFTGASAAIDTACSSSLVAASFALDAVRRSFDGLGRVDRAPRTAHAFAAGASLMLTPDMHLTLGGAGMLSHFGRCMTLDASADGYGRGEACACVLIACGDANEREEDEDTIKGDAVVAFAGSAVNQDGRSSSLTAPNGPSQRAVVREAAFGFGSGSGSGSGAVTEERVGGTRLLQMHGTGTPLGDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6W3</accession>
    <name>C1N6W3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53463</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063802.1">
        <property type="nucleotide sequence ID" value="XM_003063756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6W3"/>
    <dbReference type="GeneID" id="9689064"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53463"/>
    <dbReference type="eggNOG" id="ENOG502RZQ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10480983at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="612"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="644"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="488"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="722" mass="77133" checksum="68437E9980C0E5FB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6Z1</accession>
    <name>C1N6Z1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53492</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063638.1">
        <property type="nucleotide sequence ID" value="XM_003063592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6Z1"/>
    <dbReference type="GeneID" id="9689079"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53492"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="106" mass="10515" checksum="E62CF7FA0C80CDB3" modified="2009-05-26" version="1">MPRTSVEDAVVALSVALPSIPWVKAWTSARAKRTTRGRRGKGERDADAGAGAGAGAGAGVAAVVAAFASVPGRLHLGSHAVAIAACGTVLARGGMGKRGRARAKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7B2</accession>
    <name>C1N7B2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_11037</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063867.1">
        <property type="nucleotide sequence ID" value="XM_003063821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7B2"/>
    <dbReference type="STRING" id="564608.C1N7B2"/>
    <dbReference type="GeneID" id="9689148"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11037"/>
    <dbReference type="eggNOG" id="KOG2920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FQSESVW"/>
    <dbReference type="OrthoDB" id="1723750at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018064">
        <property type="term" value="F:protein-L-histidine N-tele-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH52240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="197" mass="20813" checksum="64190B87BCB2F806" modified="2009-05-26" version="1" fragment="single">DVVKGKYEGGFKLWECAVDLVRFIMTLPEEEEEDDASASAVLELGCGHGLPAIAAATRGAKRVVFADYNPEVLSSLTIPNVRANFAQLYDAANAAAAPPPSTSFVGGDWSDLPRFVPRASADVVLAAETIYAPESYDAHPPDGVALIAAKSHYFGVGGGTALFKTACEKTGVFAVRTAREFSDGASNVREILVVTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7F9</accession>
    <name>C1N7F9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_43093</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063891.1">
        <property type="nucleotide sequence ID" value="XM_003063845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7F9"/>
    <dbReference type="GeneID" id="9689332"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43093"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="127" mass="13617" checksum="18D8A0C1CD56AD59" modified="2009-05-26" version="1">MTPRSSRRARFRGVLACVLALVVVVATAAAFARSGGAARFFSYPPSSSSSSSSSSSSSIKRPLIVMITPTYARASAASPPQANALLRLRSAMCAGRRHRFVWVLVSSEVRSIHWFPYDRVGVVNAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7T1</accession>
    <name>C1N7T1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_23001</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Consists of at least two heavy chains and a number of intermediate and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the dynein light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063963.1">
        <property type="nucleotide sequence ID" value="XM_003063917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7T1"/>
    <dbReference type="STRING" id="564608.C1N7T1"/>
    <dbReference type="GeneID" id="9689587"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23001"/>
    <dbReference type="eggNOG" id="KOG3430">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KEPEGPC"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21453">
        <property type="entry name" value="DLC-like_DNAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000002">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF2">
        <property type="entry name" value="DYNEIN AXONEMAL LIGHT CHAIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 11" id="KW-0243">Dynein</keyword>
    <keyword evidence="4 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00057688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH51585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="113" mass="12520" checksum="073BC3005846E7DA" modified="2009-05-26" version="1">MTTEGGLAEIPADREAFLKLAQYPLIKHTDMESEMRQEAVEICAGAVEKYCQPGVEDAEKASQLIKESMDKKFGAPWNVVTGSYYSFEITAEVKHLLYVFIGGATAVVVWKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7T8</accession>
    <name>C1N7T8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_49067</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the RING-type zinc finger family. LOG2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063967.1">
        <property type="nucleotide sequence ID" value="XM_003063921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7T8"/>
    <dbReference type="STRING" id="564608.C1N7T8"/>
    <dbReference type="GeneID" id="9689408"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49067"/>
    <dbReference type="eggNOG" id="KOG4265">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MKENIQP"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16789">
        <property type="entry name" value="mRING-HC-C3HC5_MGRN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000115">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase LOG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045195">
        <property type="entry name" value="LOG2-like_mRING_C3HC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045194">
        <property type="entry name" value="MGRN1/RNF157-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058981">
        <property type="entry name" value="MGRN1/RNF157-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22996">
        <property type="entry name" value="MAHOGUNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22996:SF0">
        <property type="entry name" value="RE60872P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26192">
        <property type="entry name" value="RNF157-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0519">Myristate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="225"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH51589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="285" mass="29987" checksum="A4DD8B92BB386C2F" modified="2009-05-26" version="1">MPPPQPPPPPPAVERTTKTATIRNHVNVKKTSVSCSAANPFSPNKLKISFKFDANLPCHSSVFVLAIEDRSAPGNALSQKVNAPGSAPRRVAHEKGLGQTYETAFTVDVSPYSLAELTSDNPDGPYAIVIRLECVTGGASAVEDVGTAPVGAPGCAQPSWVQHQTTFCKLRKRDDGSWGVIATKQKISVDGKSYELQEIFGIENCATGNPMGGGGGGGGDEGKECVVCLSEPRDTTVLPCRHMCMCGGCARELRHQSNKCPVCRSPVESLLEIKIADRDGGAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8A9</accession>
    <name>C1N8A9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_66335</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064049.1">
        <property type="nucleotide sequence ID" value="XM_003064003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8A9"/>
    <dbReference type="GeneID" id="9689490"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66335"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="111" mass="11882" checksum="EED5692C750DD951" modified="2009-05-26" version="1">MHGPRVARLVHAAASGSGLGVGRGGGLFRVDIVREPDAEVDGVVALAVGRRARDGETELADFLALVRDGHADRFGVNVKRYRVGAREGVERAFDDEARAEGIEDVETPSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8E8</accession>
    <name>C1N8E8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54055</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064255.1">
        <property type="nucleotide sequence ID" value="XM_003064209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8E8"/>
    <dbReference type="GeneID" id="9689696"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54055"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="73" mass="8497" checksum="7DC28D9A61900322" modified="2009-05-26" version="1">MPNTTETDYFIGTTQGKTKDGKLTHRIIVSQVIRLVDEEGFEEDWKQEDIEIDCERLWKLVEVVDDLVVKKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8N1</accession>
    <name>C1N8N1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_3244</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064112.1">
        <property type="nucleotide sequence ID" value="XM_003064066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8N1"/>
    <dbReference type="GeneID" id="9689738"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3244"/>
    <dbReference type="eggNOG" id="ENOG502QU5X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TIAPAHY"/>
    <dbReference type="OrthoDB" id="421671at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF2">
        <property type="entry name" value="LYSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="318" mass="34519" checksum="89F56CE8CF7B45DC" modified="2009-05-26" version="1" fragment="single">RRTVTRPIVDGIIWSLEQEQALDVLAMNVRTTVVKLAADGSLVVFSPQAPTGEFFRAIDALGPVSHVVLPTYALEHKVYLPAFCRRYPNARVWVADGIWSVPIDLPLPLLGIDPSSGGVLKRAEDRGADDVAPPWADEIDYKVLRVDSAGANPYVEAVFLHAASKTLIVTDLVLSIPATPPEVISRERLLNLAPNDPADAPAADTEENLKIGWAKASLVVSFLGPSRQSQIKGGAYDGKLKWEPGFEASFEKISDRLIPSPILRTLVFSKGKGPTRRFVNEVCDDWGGQFETIAPAHYDAPVPGDCASLRAAFAFIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8Y9</accession>
    <name>C1N8Y9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54293</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064364.1">
        <property type="nucleotide sequence ID" value="XM_003064318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8Y9"/>
    <dbReference type="STRING" id="564608.C1N8Y9"/>
    <dbReference type="GeneID" id="9689805"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54293"/>
    <dbReference type="eggNOG" id="KOG2992">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5599646at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039191">
        <property type="entry name" value="Nopp140-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007718">
        <property type="entry name" value="Srp40_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216:SF1">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05022">
        <property type="entry name" value="SRP40_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Srp40 C-terminal" evidence="1">
        <location>
            <begin position="15"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="90" mass="10430" checksum="70EDBDBA3D50DCAF" modified="2009-05-26" version="1">MIQSILDRSIYSVNVEEWMGKKGSWDNTYEGTFGEDGVGWKAQAVLGQVKGDRFRHEKNKRKRSTYRGGLIDDQKVNSIKFEHSDDELFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRC2</accession>
    <name>C1KRC2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS8c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps8</name>
        <name evidence="6" type="ORF">MicpuC_chl21</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="6"/>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRC2"/>
    <dbReference type="STRING" id="564608.C1KRC2"/>
    <dbReference type="OMA" id="NSAYHDT"/>
    <dbReference type="OrthoDB" id="409928at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_uS8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001109">
        <property type="entry name" value="PRK00136.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACO50754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="122" mass="13532" checksum="B1F18FA0971D472C" modified="2009-05-26" version="1">MINDTIADMLTRLRNAHLANKPSVVLRATRVTRNIAQLLFQEGFLSNIEPEANGMFEVSLKSSVKTFQRVSTPGVRMYVNHKELPRVLNGMGVAIISTSQGIMTEKKARALGIGGEVLCYLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRD3</accession>
    <name>C1KRD3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12 13">Photosystem II reaction center protein Z</fullName>
            <shortName evidence="12">PSII-Z</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">psbZ</name>
        <name evidence="16" type="ORF">MicpuC_chl36</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="16"/>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna, regulates electron flow through the 2 photosystem reaction centers. PSII is a light-driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating a proton gradient subsequently used for ATP formation.</text>
    </comment>
    <comment type="function">
        <text evidence="12">May control the interaction of photosystem II (PSII) cores with the light-harvesting antenna, regulates electron flow through the 2 photosystem reaction centers. PSII is a light-driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating a proton gradient subsequently used for ATP formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 12">PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbY, PsbZ, Psb30/Ycf12, at least 3 peripheral proteins of the oxygen-evolving complex and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Plastid</location>
            <location evidence="12">Chloroplast thylakoid membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12 13">Belongs to the PsbZ family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRD3"/>
    <dbReference type="STRING" id="564608.C1KRD3"/>
    <dbReference type="OMA" id="MSIVFQI"/>
    <dbReference type="OrthoDB" id="1161947at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042549">
        <property type="term" value="P:photosystem II stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.740">
        <property type="entry name" value="Photosystem II PsbZ, reaction centre"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00644">
        <property type="entry name" value="PSII_PsbZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002644">
        <property type="entry name" value="PSII_PsbZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036512">
        <property type="entry name" value="PSII_PsbZ_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03043">
        <property type="entry name" value="PS_II_psbZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34971">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER PROTEIN Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34971:SF2">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER PROTEIN Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01737">
        <property type="entry name" value="Ycf9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161055">
        <property type="entry name" value="PsbZ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9 12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 12 13" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="10 12 13" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="16" id="KW-0934">Plastid</keyword>
    <keyword evidence="4 12 13" id="KW-0674">Reaction center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="8 12 13" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="6 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002911314" description="Photosystem II reaction center protein Z" evidence="15">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACO50765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="62" mass="6433" checksum="3D7F89681EA9B990" modified="2009-05-26" version="1">MLFIFQLTLLAFIGLSLALVVGVPVLLASPDGWASSKGLVLSGSALWILLVFVVGALNSFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGK9</accession>
    <name>C1MGK9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_49852</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054793.1">
        <property type="nucleotide sequence ID" value="XM_003054747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGK9"/>
    <dbReference type="GeneID" id="9681050"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49852"/>
    <dbReference type="OMA" id="CAMERPR"/>
    <dbReference type="OrthoDB" id="2020984at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005923">
        <property type="term" value="C:bicellular tight junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349">
        <property type="entry name" value="CINGULIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349:SF6">
        <property type="entry name" value="MYOSIN-6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3" id="KW-0518">Myosin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="172"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="253"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="329"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="550"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="329"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="464"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="495"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="699" mass="78338" checksum="79BFB9B0D638FF98" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH88</accession>
    <name>C1MH88_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50091</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055449.1">
        <property type="nucleotide sequence ID" value="XM_003055403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH88"/>
    <dbReference type="GeneID" id="9680485"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50091"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="99" mass="10641" checksum="5920BE8C67F96BC3" modified="2009-05-26" version="1">MSEAPPAAARRRAGATASAADDDDDDATTTTKATMNRRRGYARNRVPVIGGRPVKTRTSGMRKLHEPAGAGVWVAIFGSVLLFAGIQAFIRWKWADELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHE5</accession>
    <name>C1MHE5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_61314</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054943.1">
        <property type="nucleotide sequence ID" value="XM_003054897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHE5"/>
    <dbReference type="GeneID" id="9680323"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61314"/>
    <dbReference type="OMA" id="FGHLLMR"/>
    <dbReference type="OrthoDB" id="10678829at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="524"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="302"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="438"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="657" mass="67850" checksum="665A94FB80E50AA1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI14</accession>
    <name>C1MI14_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Uncharacterized protein ycf33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_50397</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ycf33 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055587.1">
        <property type="nucleotide sequence ID" value="XM_003055541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI14"/>
    <dbReference type="GeneID" id="9681154"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50397"/>
    <dbReference type="eggNOG" id="ENOG502SF85">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1900844at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008470">
        <property type="entry name" value="Uncharacterised_Ycf33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05421">
        <property type="entry name" value="DUF751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="73"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="109"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="251" mass="26057" checksum="91322D82349D3A68" modified="2009-05-26" version="1">MTPSTLAHARCALVTTTSSTSYAPRGACRRAAAPRVVVVARLYGGAHRAATTSSRKARSSGERRGVDALLRREENVAASRTSDAAATRSTDAAEEDAAVVADPDDDGAGARPTIRASSSSSSSSSALFSSSEIAAAALFSAFAFAFFTAAEPSSAAENATAAFADASDASDALFQIAGGEVPFWANMVKYARFAISVMVGFAFMFGRPIVGLLKKPQTAVLVIGGGVAGYKFFRFTIETMLGMNDDMTLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJA6</accession>
    <name>C1MJA6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50870</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055279.1">
        <property type="nucleotide sequence ID" value="XM_003055233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJA6"/>
    <dbReference type="GeneID" id="9680471"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50870"/>
    <dbReference type="OrthoDB" id="567850at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="167" mass="17055" checksum="3D79DB4FD5703605" modified="2009-05-26" version="1">MRAVAVAVAGRPPTHVASPRALTRARGSIARPPRATEKDADADAPLSARVAAPDVKKKKDVDDDDDASIAASMAAARACEASGMSPGAGLSSAEDQAEAAFADMINTTVDVTGEALDADARARLAEGGRMDGASTSRKSGGMWSDVRDLFGALGKGAHIVRQKNGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJC7</accession>
    <name>C1MJC7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_38281</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055291.1">
        <property type="nucleotide sequence ID" value="XM_003055245.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MJC7"/>
    <dbReference type="GeneID" id="9680491"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38281"/>
    <dbReference type="eggNOG" id="ENOG502QPYZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DYAFQMM"/>
    <dbReference type="OrthoDB" id="2161379at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052640">
        <property type="entry name" value="Gemin-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056421">
        <property type="entry name" value="TPR_GEMI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362:SF1">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23774">
        <property type="entry name" value="TPR_GEMI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="92"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Gem-associated protein 5 TPR" evidence="5">
        <location>
            <begin position="1099"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="862"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="874"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="893"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1297" mass="133407" checksum="27164DCF3C1BA46C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJN5</accession>
    <name>C1MJN5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="11">PPIase</shortName>
            <ecNumber evidence="11">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_64038</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.</text>
    </comment>
    <comment type="function">
        <text evidence="11">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="11"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055851.1">
        <property type="nucleotide sequence ID" value="XM_003055805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJN5"/>
    <dbReference type="STRING" id="564608.C1MJN5"/>
    <dbReference type="GeneID" id="9681418"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64038"/>
    <dbReference type="eggNOG" id="KOG0883">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000014">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase cyp65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF1">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="12">
        <location>
            <begin position="83"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH59227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="244" mass="26557" checksum="D1963AC53E44104A" modified="2009-05-26" version="1">MGNDPHQAEKRREAEMLERFKVVGDHVKISTKTNAMRTTGAGSTSFTSTVMGNGTQGVNTRCEEIVYRNPKKKGYVRLNTTHGNVNVELHCDVAPRACENFITLCLAGYYDGVGFHRSIKNFMIQGGDPSGTGTGGQCMWGGKFKDEITHLGHSGRGVLSMANAGPHTNGSQFFILYKSARHLDGKHTVFGNVVGGMETLAAFEAEPTEDDDRPRNAISILSTEARSPSHWSPYDPVRVVNAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK50</accession>
    <name>C1MK50_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55210</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056329.1">
        <property type="nucleotide sequence ID" value="XM_003056283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK50"/>
    <dbReference type="GeneID" id="9681307"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55210"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="78" mass="8201" checksum="AE34846099180E33" modified="2009-05-26" version="1">MGHISVALVSDLGNRIAGAPISYALRTARDSENFHAGAAAQILFMESDTACDFHAAPAPCARDAHTGLRDHIVELLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK74</accession>
    <name>C1MK74_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sister chromatid cohesion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_55223</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the SCC2/Nipped-B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056333.1">
        <property type="nucleotide sequence ID" value="XM_003056287.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MK74"/>
    <dbReference type="GeneID" id="9681316"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55223"/>
    <dbReference type="eggNOG" id="KOG1020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GSTDWPA"/>
    <dbReference type="OrthoDB" id="418242at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090694">
        <property type="term" value="C:Scc2-Scc4 cohesin loading complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061775">
        <property type="term" value="F:cohesin loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140588">
        <property type="term" value="P:chromatin looping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034087">
        <property type="term" value="P:establishment of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071169">
        <property type="term" value="P:establishment of protein localization to chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23958">
        <property type="entry name" value="SCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026003">
        <property type="entry name" value="Cohesin_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024986">
        <property type="entry name" value="Nipped-B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033031">
        <property type="entry name" value="Scc2/Nipped-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704:SF18">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12765">
        <property type="entry name" value="Cohesin_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12830">
        <property type="entry name" value="Nipped-B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Sister chromatid cohesion C-terminal" evidence="7">
        <location>
            <begin position="1246"/>
            <end position="1438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1565" mass="175635" checksum="599228A7F874C0E5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKF4</accession>
    <name>C1MKF4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_55318</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055987.1">
        <property type="nucleotide sequence ID" value="XM_003055941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKF4"/>
    <dbReference type="STRING" id="564608.C1MKF4"/>
    <dbReference type="GeneID" id="9681946"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55318"/>
    <dbReference type="eggNOG" id="KOG0270">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TPESTIW"/>
    <dbReference type="OrthoDB" id="270624at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044285">
        <property type="entry name" value="PWP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="303"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="435"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="546" mass="59111" checksum="739A2456B020F3FF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKN8</accession>
    <name>C1MKN8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64519</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056026.1">
        <property type="nucleotide sequence ID" value="XM_003055980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKN8"/>
    <dbReference type="GeneID" id="9681516"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64519"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="774"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="867"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="586"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="928" mass="96196" checksum="09CE8D2A0E1C15F7" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKP0</accession>
    <name>C1MKP0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_38460</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056028.1">
        <property type="nucleotide sequence ID" value="XM_003055982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKP0"/>
    <dbReference type="STRING" id="564608.C1MKP0"/>
    <dbReference type="GeneID" id="9681517"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38460"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="259" mass="28894" checksum="C801B72165F3231B" modified="2009-05-26" version="1">MSNERKRRRADPPAREAPSVDVDDDVSPGDVLRLVSARFDELEEKLERVREEHVETRAELTATRRTPAELIDIVKSVNPTFDVNEQLASVVFSHVTDVCTRVALSLVNSVWRKASKVASSQPLTLRFNIEMLEWYKKGALHGNTECEMIVGCVYYHGVLVKKDIDTASQYFEKVAAKGDAVAQNSVGCCLFEKGRYDESFKWFTKAAAQGIISADCNLGIAYEHGCGVTKDIPKALEMYTKAAEKGDDLAAKFLRKLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLG2</accession>
    <name>C1MLG2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">40S ribosomal protein S10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPS10</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_55703</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056162.1">
        <property type="nucleotide sequence ID" value="XM_003056116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLG2"/>
    <dbReference type="STRING" id="564608.C1MLG2"/>
    <dbReference type="GeneID" id="9682033"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55703"/>
    <dbReference type="eggNOG" id="KOG3344">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NWQHLYF"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000025">
        <property type="entry name" value="40S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="144" mass="16672" checksum="B523D89D2974F5F4" modified="2009-05-26" version="1">MLIPKKNRKEVYKYLFREGVIYAKKDFNLPSHPEIKDVPNLQVIKLMQSFTSKELVKQIFSWRYFYWYLTNEGIEYLREYLNLSADVVPNTLKKSTRPPTRPMADERAPRRDAPPGRGGGGREGYRAERPGGFGRGGGDKPQYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLJ9</accession>
    <name>C1MLJ9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL53</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">39S ribosomal protein L53, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_55740</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL53 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056180.1">
        <property type="nucleotide sequence ID" value="XM_003056134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLJ9"/>
    <dbReference type="STRING" id="564608.C1MLJ9"/>
    <dbReference type="GeneID" id="9681846"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55740"/>
    <dbReference type="eggNOG" id="ENOG502SBKM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DQNAHPP"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052473">
        <property type="entry name" value="mtLSU_mL53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019716">
        <property type="entry name" value="Ribosomal_mL53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33618">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L53, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33618:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10780">
        <property type="entry name" value="MRP_L53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="111" mass="12553" checksum="57EBB6AC39FFD622" modified="2009-05-26" version="1">MSLRQLVSIQFSATDPRSAAVREFLQRCLAPKARESNPDCIVFHNVRSDDCPPVVSVEFVNGFKDQFNCHKLTVSDIMSRICDISDTMNSEELLEKSGLKTSELNLRSFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLX5</accession>
    <name>C1MLX5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56301</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057296.1">
        <property type="nucleotide sequence ID" value="XM_003057250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLX5"/>
    <dbReference type="GeneID" id="9682279"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56301"/>
    <dbReference type="OMA" id="TETICWK"/>
    <dbReference type="OrthoDB" id="10528852at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="226" mass="23950" checksum="D75C9FA8F71AFD83" modified="2009-05-26" version="1">MATVALARGANVSALAPSSCSRRRCRRRVDARWTTPGRATVASSASADDRAGESSGEIRPKRATGGRVGRAASTPGGGAAGTSPARRVVRRKPTVDRGKARTDEEKAAAMRELKAKAIAPRIDALVAVVVDACGRDEYKRANVAYAELKNDCADGSIPAEVFTAMLELCARLRMPSSAEGIFVDSVAAGHAPTETICWKLVEIFEQAGEKTRAEKVLAYMETRGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMG7</accession>
    <name>C1MMG7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56523</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057402.1">
        <property type="nucleotide sequence ID" value="XM_003057356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMG7"/>
    <dbReference type="GeneID" id="9682365"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56523"/>
    <dbReference type="eggNOG" id="ENOG502SAKF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GWIATFH"/>
    <dbReference type="OrthoDB" id="10058237at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="331" mass="35631" checksum="B87D71917BE1FADA" modified="2009-05-26" version="1">MAGQRRAREDAVAVVDVLKGSTTADDSGDDELDAVVVNPATVARLARYAEWGDGGVKGFFEPGLCALYASLDAFHVRNGVKGSLAEIGVYHGKSFAPLALMRRDDERCVAVDCFDAQEHNVDDSGAGDRAAFERNVARAMRACREDDDDDEDEDGDGSDGSDGTDPAWLRVVEADSATTPPETLTRAADGQTFRIFSIDGCHTESHTAADVETASRTLHDLGVVVVDDAFNPDWPGVVAGLFRWTERNRNRNRNGGGASTAPPLVPFAIGYNKVLMCRPDAHDALLTHVKTSRETRASVRKTAEFLGGEVVVLPHGWISTFHGNERLSSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMS4</accession>
    <name>C1MMS4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_32552</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Nucleoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the exportin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057455.1">
        <property type="nucleotide sequence ID" value="XM_003057409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMS4"/>
    <dbReference type="STRING" id="564608.C1MMS4"/>
    <dbReference type="GeneID" id="9682419"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32552"/>
    <dbReference type="eggNOG" id="KOG2020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WAFKHNN"/>
    <dbReference type="OrthoDB" id="27218at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000022">
        <property type="entry name" value="protein EXPORTIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041123">
        <property type="entry name" value="CRM1_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041235">
        <property type="entry name" value="Exp1_repeat_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014877">
        <property type="entry name" value="XPO1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040485">
        <property type="entry name" value="XPO1_repeat_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF2">
        <property type="entry name" value="EXPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08767">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18777">
        <property type="entry name" value="CRM1_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18784">
        <property type="entry name" value="CRM1_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18787">
        <property type="entry name" value="CRM1_repeat_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01102">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="6">
        <location>
            <begin position="41"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1072" mass="121546" checksum="1ABD03B9AF62D942" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMT4</accession>
    <name>C1MMT4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_56648</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057459.1">
        <property type="nucleotide sequence ID" value="XM_003057413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMT4"/>
    <dbReference type="STRING" id="564608.C1MMT4"/>
    <dbReference type="GeneID" id="9682898"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56648"/>
    <dbReference type="eggNOG" id="KOG4649">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YVGTMEG"/>
    <dbReference type="OrthoDB" id="536707at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052091">
        <property type="entry name" value="Beta-ala_Activ/Resist"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44394">
        <property type="entry name" value="BETA-ALANINE-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44394:SF1">
        <property type="entry name" value="BETA-ALANINE-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002911988" evidence="2">
        <location>
            <begin position="35"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrrolo-quinoline quinone repeat" evidence="3">
        <location>
            <begin position="161"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrrolo-quinoline quinone repeat" evidence="3">
        <location>
            <begin position="301"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="604" mass="63604" checksum="BCE05C1BABFD7EC3" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN54</accession>
    <name>C1MN54_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_62683</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057520.1">
        <property type="nucleotide sequence ID" value="XM_003057474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN54"/>
    <dbReference type="GeneID" id="9682959"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_62683"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="269" mass="30613" checksum="B922989D714F5DFF" modified="2009-05-26" version="1">MNRAGLLLDFSFSSVILLFRFDIYCTLLQLLSAAPLSRDVSVVSALVPADALDVAADRSRRVVPHPTVPAPAGGVRLATPRQPRRVPLDDARAHPASFPRAERVPVRYPPHRAVVVHDDRAEILEGDSLAEPNAPPRAAAAAVVVVADASRLEDGDPARGVVRAVGRRRRRWRRRRRDDDARRRRDERQREEEEERKEERRRRRRLGAPRRPRRSRSRGSVLAPRPARRRRHRVTTTTTTTRAVPSTARAVAPRRRRRRRDAPRGVRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNG1</accession>
    <name>C1MNG1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_55883</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057099.1">
        <property type="nucleotide sequence ID" value="XM_003057053.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MNG1"/>
    <dbReference type="GeneID" id="9682103"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55883"/>
    <dbReference type="eggNOG" id="KOG0724">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RDECERG"/>
    <dbReference type="OrthoDB" id="77564at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033053">
        <property type="entry name" value="Hir3/CABIN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502:SF7">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="384"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="385"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="7">
        <location>
            <begin position="386"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="247"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="565"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="612"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="875"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1549"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1748"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1921"/>
            <end position="2044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2971"/>
            <end position="3028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="350"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="571"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="668"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="707"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="728"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="783"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="876"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="887"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="902"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1561"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1587"/>
            <end position="1600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1753"/>
            <end position="1775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1952"/>
            <end position="1961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1976"/>
            <end position="1996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="2971"/>
            <end position="2982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2983"/>
            <end position="2993"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="3028" mass="316228" checksum="95E4FB99CAE539F5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNI0</accession>
    <name>C1MNI0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46576</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056655.1">
        <property type="nucleotide sequence ID" value="XM_003056609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNI0"/>
    <dbReference type="GeneID" id="9682547"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46576"/>
    <dbReference type="OMA" id="CEVRCEM"/>
    <dbReference type="OrthoDB" id="495933at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="193" mass="20713" checksum="BD6B18039DA6E222" modified="2009-05-26" version="1">MATTAARAGLAPPVASVAPRRSFDRVAVRKSSRGLANSSRVVVVVVDRRRRRAAATTTTRAGINTDADYNCVVRNDGVIISSDIPSGVYEVSSWWHGSGDDGDPARAPRCDSERQRGCEVRCEMTAEGELVCEGLTSGRYRVINAEDADAECSVEDGAFECTTSFDDDGPPTQDTGDVDLQESEENKSFRMGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNS0</accession>
    <name>C1MNS0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_38587</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057158.1">
        <property type="nucleotide sequence ID" value="XM_003057112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNS0"/>
    <dbReference type="STRING" id="564608.C1MNS0"/>
    <dbReference type="GeneID" id="9682085"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38587"/>
    <dbReference type="OMA" id="SEVWHIL"/>
    <dbReference type="OrthoDB" id="545599at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="480" mass="49670" checksum="430077700C5C8980" modified="2009-05-26" version="1">MTADDAVVCEVLVDDDERAGGDSLRKLEALVDDLTVSSSASHRGGADADDAAASARRRANLILLCRRVASDARAAVFARAHGAEPVLLCALNRAIRDGDDALAELVGDAVAASARCDGGDDGGATIELLAVGGSQVGGAAATRAPGVERVRLRRAGVDVDVHESSWNDAGLAWRIWGAARVLAHAVDASSGDGVEEEGEEDADGGLVDARGRRVLELGAGCGLCGLAAAACGAREVVLTEGAPGALKALERSAAAFEAAAEEAQTETSEKTSEKKTVRVAFLDWRDDMARLDADDDGAASTTASSTNFVHKRVGGDDAWLSSLPRLADDDVFDCVLGSDLLYDASHAAPLAACIARRLSTAPRAAAHVALAVRRGELAAELCERAGERGLVAEARALDVFAGEASALETHQGGHVTREEHPEAEAWRAAGGEAFARGDGLVVRAGTDEGTMTEAVRGLEGRVALFTFRRRASPARPRTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPS4</accession>
    <name>C1MPS4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_67138</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057635.1">
        <property type="nucleotide sequence ID" value="XM_003057589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPS4"/>
    <dbReference type="GeneID" id="9683041"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_67138"/>
    <dbReference type="OMA" id="GHMESAV"/>
    <dbReference type="OrthoDB" id="5794653at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="201" mass="21476" checksum="E3FAE61170B20259" modified="2009-05-26" version="1">MTSNPRLRAPSAAGISSAVLSSAGNPPCGGSGGGDYYRNAPPPRRDDSIWGWLTGESDDDGGAAGYSSNYAGNPNDDTLTWLANSANYYAAEMARNVKSVTDAIAEELLGPAEDEEGEEIEEEDASVRGTGEVVAGGAVGNKGRRKKKKEEPKPKPKPKKKTLEEEEDDEDDVIGGVLNLLGLEDDEEDEPYVRRDCKKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPV3</accession>
    <name>C1MPV3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_39199</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058013.1">
        <property type="nucleotide sequence ID" value="XM_003057967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPV3"/>
    <dbReference type="STRING" id="564608.C1MPV3"/>
    <dbReference type="GeneID" id="9683044"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_39199"/>
    <dbReference type="OMA" id="DEWWDEM"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024738">
        <property type="entry name" value="Hfi1/Tada1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12767">
        <property type="entry name" value="SAGA-Tad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="97"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="166"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="331"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="433"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="522"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="707"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="284"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="533"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="724"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="796" mass="84720" checksum="E1F6B9677C768312" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ75</accession>
    <name>C1MQ75_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_57186</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057709.1">
        <property type="nucleotide sequence ID" value="XM_003057663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ75"/>
    <dbReference type="STRING" id="564608.C1MQ75"/>
    <dbReference type="GeneID" id="9683516"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57186"/>
    <dbReference type="eggNOG" id="ENOG502RUZ6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DWGLCPA"/>
    <dbReference type="OrthoDB" id="548857at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1740.10">
        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="AlgH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46065">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46065:SF3">
        <property type="entry name" value="FI20425P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143456">
        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="11">
        <location>
            <begin position="9"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="178"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="202"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH57660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="483" mass="51784" checksum="97A23993976CB5DE" modified="2009-05-26" version="1">MATTRTPRVSEGSIPSCRFCFDGGSDDEPLVTPCRCTGTSAHVHARCLLKWQTWRILTTASSGGGTEERAKSLSCSVCKATYATAPPSMSELLTHVRGEGGASLAALLVPGTLLVRNVSQFDESSLANAPQWLRWVFNRKRAHWNKAVYLITKVVPGRGVGGTDVLVGVNLTARLEKATRNSRGDDDDDEEKPLEAEGLSTSDDDDEEEDDDDGEIEVNEEEKEEEEEEENDDDEARGRPRRRLADAAAADDDEDATTSSASDGRDGEIADPALAAALSETEEVHASMSNDAAALLELEDDDETFGDLSLEMMPHVRRYVGGPVRRDKRVVLLVSSAAESTLSAPTIALPLDADVEGAGASAERAYVYHQRGSDAAEYVEEVLAEAVGDALNAAGDDDDDDAAGDGGGGGDDDDDEIVVPKVHVFNGHARWSRSQLMNEVARGDWGLCPATRRDLGAGWRVAGNAFWSTLFDSGRPIFAKVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQQ8</accession>
    <name>C1MQQ8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Magnesium-protoporphyrin IX methyltransferase chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CHLM</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_57377</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058168.1">
        <property type="nucleotide sequence ID" value="XM_003058122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQQ8"/>
    <dbReference type="STRING" id="564608.C1MQQ8"/>
    <dbReference type="GeneID" id="9683240"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57377"/>
    <dbReference type="eggNOG" id="KOG1270">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WNRIYSE"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046406">
        <property type="term" value="F:magnesium protoporphyrin IX methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010251">
        <property type="entry name" value="Mg_prot_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010940">
        <property type="entry name" value="Mg_prot_MeTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02021">
        <property type="entry name" value="BchM-ChlM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43464">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43464:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07109">
        <property type="entry name" value="Mg-por_mtran_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51556">
        <property type="entry name" value="SAM_MT_MG_PIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Magnesium-protoporphyrin IX methyltransferase C-terminal" evidence="5">
        <location>
            <begin position="233"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="330" mass="34436" checksum="18766037BEF40A73" modified="2009-05-26" version="1">MPAVTSCTARAVVAPRASADKANKKPAAVPSAKPASLAAASFAAASLAPSAAFAATEAISQTASGVGLAVGGAAAVAGVAGLLVVTDPNRRRESMMSETGGDEAESVRNYFNTVGADRWKKIYGETDEVNKVQLDIRQGHQKTVDKVIGWMAGKDMNGVTVCDAGCGTGSLAIPLALSGAAVSASDISSAMVGEAEVRFNNEIAAGKKAPSVAPKFEALGLEECSGKYDVVTCIDVMIHYPTDRVNGMINHLASLSEDKLIVSFAPKTLAYSILKRVGELFPGPSKATRAYLHAEEDVESALKAAGFKVTRREMTATQFYFSRLLECERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQV9</accession>
    <name>C1MQV9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ADP-ribosylation factor-like protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_45465</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057823.1">
        <property type="nucleotide sequence ID" value="XM_003057777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQV9"/>
    <dbReference type="STRING" id="564608.C1MQV9"/>
    <dbReference type="GeneID" id="9683636"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45465"/>
    <dbReference type="eggNOG" id="KOG0074">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EGMEWVC"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04155">
        <property type="entry name" value="Arl3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000281">
        <property type="entry name" value="ADP-ribosylation factor-like protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044612">
        <property type="entry name" value="ARL2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45697">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="23"/>
            <end position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH57774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="177" mass="19720" checksum="B0FF577693D7BAE9" modified="2009-05-26" version="1">MGLLSLLRRLKKSGGEARILILGLDNAGKTTILRKLSEEDITTTTPTQGFNIKSILHNGFKLNVWDIGGQKTIRPYWRNYYENTEALIYVVDAADRKRVDEAGFELAEILGEDKLATVPLLVFANKSDLITALSADDVAESLSLFNIKDRPWQIQACSAKKGDGLEEGLQWVVKQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>C1MR14</accession>
    <name>C1MR14_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor G, chloroplastic</fullName>
            <shortName evidence="6">cEF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_26499</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Plastid</location>
            <location evidence="6">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057849.1">
        <property type="nucleotide sequence ID" value="XM_003057803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MR14"/>
    <dbReference type="STRING" id="564608.C1MR14"/>
    <dbReference type="GeneID" id="9683287"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26499"/>
    <dbReference type="eggNOG" id="KOG0465">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MDDMVGG"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04088">
        <property type="entry name" value="EFG_mtEFG_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000006">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000003">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000029">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03063">
        <property type="entry name" value="EF_G_plantC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030848">
        <property type="entry name" value="EF_G_plantC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047872">
        <property type="entry name" value="EFG_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009381">
        <property type="entry name" value="PRK12740.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="56"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="129"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="183"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="748" mass="81750" checksum="5609A13BD53E3164" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRB7</accession>
    <name>C1MRB7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57597</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057902.1">
        <property type="nucleotide sequence ID" value="XM_003057856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRB7"/>
    <dbReference type="GeneID" id="9683715"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57597"/>
    <dbReference type="OMA" id="VANTFCV"/>
    <dbReference type="OrthoDB" id="10550589at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912089" evidence="2">
        <location>
            <begin position="29"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="441" mass="47194" checksum="5E5511440056DC8D" modified="2009-05-26" version="1">MRLLKFRRSFVLAAIAVLATLSLPSVRALEPLPFVEIPLYVGESKQTLGIYEGDNVNEAVDAFGATHDLSPDELKTLKEEVTKRFVAIADVVRAGASPGASFDGKEPLFQFPVGVGDGKVVPLKLYEGDNLLRAVQKFAKKNGVPEDIVPSLFQQIQLKVYGENFDDPTITPLGGGAPGDASADPEAPPQLLYEFPVDVDGSGDKDNLTPLKLYRGDVLGERVKAFAEEHALDDEASDKLVAAVAERIAATQQAEKAAEEIRAKREAEALAAGEEGGEPPEPLYEIPINVDDDTYPLKLYEGDILRTAVEAFVIEHGFEITSVPIIVDAVSKQFNKDDADADAADDDGSPKPLVSFAVSMDGGDGKPLPPIALYDNEDADVVANEYCEKHGLDVKVTAPQLADALRNSLKEKTPAEKAEAPAAAATEEEKGDATTGEDKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRK7</accession>
    <name>C1MRK7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome b5 reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CB5F</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_15771</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome b5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057945.1">
        <property type="nucleotide sequence ID" value="XM_003057899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRK7"/>
    <dbReference type="STRING" id="564608.C1MRK7"/>
    <dbReference type="GeneID" id="9683762"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15771"/>
    <dbReference type="eggNOG" id="KOG0537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THPGFNN"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF25">
        <property type="entry name" value="CYTOCHROME B5 HEME-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="41"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="181"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="262" mass="28671" checksum="38E039A61C400E2F" modified="2009-05-26" version="1">MSSSTAAEATALPPPGKDLASDARVVSELKSLPSETSRAPWRKLSMREVSSHRTLRDGWIAVNGRVYDISAFATTHPGFNNAGQVSTALAIARMLGKDATAEFEEIHSDKAWRQLRDFQVGVLARDDEEDDEEDARRDASATRTPAPPVPSWLAADRDFWIAYANGVSADVLRYLTASGYPQRDDDDDDDDDDDAAAAAAAAKDDKPKSSPSSWTDRRRRRSFRGAAALAAVLALRACVRTRTARGRDHARRATRRRSISVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRL3</accession>
    <name>C1MRL3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_33561</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058894.1">
        <property type="nucleotide sequence ID" value="XM_003058848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRL3"/>
    <dbReference type="STRING" id="564608.C1MRL3"/>
    <dbReference type="GeneID" id="9683968"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33561"/>
    <dbReference type="eggNOG" id="KOG1614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YRFGPKD"/>
    <dbReference type="OrthoDB" id="10264038at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11368">
        <property type="entry name" value="RNase_PH_RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033100">
        <property type="entry name" value="Rrp45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF14">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="38"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="196"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="292" mass="31794" checksum="D5D8C46352D45FC7" modified="2009-05-26" version="1" fragment="single">MAPKDPDVLLCINNRQFILEALKEEDIRIDLRGPFDAREVAYRFGPKDGVCEVSLGKTRVLAVTSAKLEPPGGGRSNEGSVTINVEFSPMASPNFEPGRPGEEASELAVVLERAIRETGAVDVESLCVLAGRRVWNIRVDVHVLDACGNIAGAASLAANASLLSFRRPEATVDPSTQLVTVHPADAREPIPLALHHLPIAVKFGFFAEHEGLLIVDPLVDEEAVMASSLIVVLNAHGELCAVQKGGGVGVPANEIMRCVRIADKMTKELTTQLREEHKKWEGERDKRRVRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRV8</accession>
    <name>C1MRV8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_5065</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058940.1">
        <property type="nucleotide sequence ID" value="XM_003058894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRV8"/>
    <dbReference type="STRING" id="564608.C1MRV8"/>
    <dbReference type="GeneID" id="9684017"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5065"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HEQTIMC"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF963">
        <property type="entry name" value="AT08303P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="9"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="282" mass="31480" checksum="742BB1399630F0F9" modified="2009-05-26" version="1" fragment="single">LQVVPSAELELVNRLGGGAFGEVHLALWRGSEVAVKGDKRASAAASREMESFLREAHTMAALQHPNVVFIYGVVNDGERLGIVEEFMSSGSLRRLLNLHQRDRPSKNVLGAKLRARCALDVARGMAYLHSKRFVHFDLKCDNVLTARRGAKLQCKVCDFGLSKRRRSHASFVSGVNSHRGTLPWTAPELLNAPTRASEKVDVYSFAVLMWELWTGAYPYAGMHEQTIMCGIMMRSLRPDVADGENPAGSPVNGWKSLMFEAWRDKPEERPSFEEIVKRLEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS11</accession>
    <name>C1MS11_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_16944</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
            <location evidence="2">Mitochondrion nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058968.1">
        <property type="nucleotide sequence ID" value="XM_003058922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS11"/>
    <dbReference type="STRING" id="564608.C1MS11"/>
    <dbReference type="GeneID" id="9684042"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_16944"/>
    <dbReference type="eggNOG" id="KOG0742">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HKSITGG"/>
    <dbReference type="OrthoDB" id="199596at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021911">
        <property type="entry name" value="ATAD3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23075:SF0">
        <property type="entry name" value="ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23075">
        <property type="entry name" value="PUTATIVE ATP-ASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12037">
        <property type="entry name" value="ATAD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="359"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="99"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="133"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH57423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="626" mass="67089" checksum="6B020F0E29EBAB38" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS33</accession>
    <name>C1MS33_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58328</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058616.1">
        <property type="nucleotide sequence ID" value="XM_003058570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS33"/>
    <dbReference type="GeneID" id="9684416"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58328"/>
    <dbReference type="OrthoDB" id="546617at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="499" mass="55349" checksum="C55FD50E5A2CA022" modified="2009-05-26" version="1">MPSPPAKKAKPTPEAAPSPSPFELFLEADAFSAKFALVSKCDAHAREMLKRVSRGARKSVEDAEYAARVDVHRARLKAKACVDAVERLRWAAANGCPLNDARLCALVARRGCLEALKWAREQGCPWDASTPAAAARGGHLEVLKWANEQGCPMNDKVFKQAAKGGHLDVIKYLVPPAAVLVKVAPNGDELEDPDFFVDAEEDHDDEETIEEEIVVAASEGYDALADLAEELKTPVDELLRRYRDMEASSPGDEEDAETNDEDSDVDGEKKLELGLEVIVDENDFFVPFRHVVAGAACGGHVHIFNWLRFEKKWIPPGREHDDERMFRYAARGGQLEIIKWLYARDKTPDAWAAAFAARGGHLDVLKFLRMMLAPMDSTVGTGAVMSGNIDVVRWVYALGDRYVDKFWQYAFAARHGKAFVNAVSEVCNQHGYYSIKFSSISITAEEARLRSAVFAVAYGNFDLLKTLRSMSTRITDYYTTEGEEMKLITDAALGMHNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSY5</accession>
    <name>C1MSY5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57871</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058763.1">
        <property type="nucleotide sequence ID" value="XM_003058717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSY5"/>
    <dbReference type="STRING" id="564608.C1MSY5"/>
    <dbReference type="GeneID" id="9683852"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57871"/>
    <dbReference type="eggNOG" id="KOG4409">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DTTIRWC"/>
    <dbReference type="OrthoDB" id="7457040at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042171">
        <property type="term" value="F:lysophosphatidic acid acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF29">
        <property type="entry name" value="PUMMELIG, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="71"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="365" mass="40037" checksum="9343B6390FE7C973" modified="2009-05-26" version="1">MGRVLGLAERLWAGFSYSRKQCLANESALFDHLLKDRGLKWVAHDTPVTSKPDDVVHSVTVNGDATGGVDFVLVHGFANGGGCFFKNIAALGDMKLGRTHLVDWRGAGMSGRPRGEFPPTNEDEAIEYFVDGLEAWRRARLGADGAFVLLGHSMGGLIAAHYADRHPDRVRGLVLAGPAGVKAADPARIAAFKRRSLRHRFFWAVATVLWNAGATPQAFARALPFRWSPSAVRGYATRRWRALEFLDGDANAFDALVEYAAGVIMMRGVSERSMSLLLKPLGQARTEIGPVVERTPADLPVTFLYGAHDWMSPASGAEVVERMRANGRANVRCAILDDAGHYAFVDQPEKSHEVIEHALRKARWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT39</accession>
    <name>C1MT39_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_57927</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058793.1">
        <property type="nucleotide sequence ID" value="XM_003058747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT39"/>
    <dbReference type="STRING" id="564608.C1MT39"/>
    <dbReference type="GeneID" id="9683776"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57927"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="76"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="299"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="30"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="224"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="224"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH57248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="464" mass="48388" checksum="5BC633E71AD108D2" modified="2009-05-26" version="1">MCIGSFFETRGLAPLSSTDADGVASFRGFPAKRGSRSPSVADDYLSSGADATTRMSRKSTKRLRGDDADDADAPTSALRVANLSRYVTEPDVKKLFALFSPNEGGVRRVTMPREDDLVDGAHRGFAVVELENEAAARSATQMDGLLIADKYARAIFRRRRRGARALVLLVFFEVFFFFSNPELTGRLPSPPPSRHIKVCRFPLPSDADAALLGDDTPKRLLASTETATSTASARRGAANAATCDRAAAASRSLARRVPAPPPPPPPPPKAEAPDAGSPTPPKPKPNPKPRPVERDDGAKRVWVGNVRPDATAQELSALFSSFGPIARCELSSDASPTDASRDGDGARAGCRARRRPAIVKSGQHAGHGAVYFRDASAAAAAVAAAADGALRLDGASLEAWLFRDGDADAPHSSDAARAAASTSKSRGSSGAAGVASVHDVARAAMNAMIVPGKSSALAALAAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT81</accession>
    <name>C1MT81_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57968</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058819.1">
        <property type="nucleotide sequence ID" value="XM_003058773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT81"/>
    <dbReference type="GeneID" id="9683880"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57968"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="167" mass="17670" checksum="189491FA16290750" modified="2009-05-26" version="1">MTGPRVIPARAPCARASPTRPRRAARTSRGVATRALPPANEVAGFVIGVRRVAIPIPIPTPTPTPTPIPTRSLVREPPSRRVLRPSPSLTSRSRSVHDHRPQGGLVALVLSINKLDAVIARAQVRGFEESSGKKGTTRSPSGGGGGNIFVVPDDDDDDDDDDDARTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTB1</accession>
    <name>C1MTB1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CALK protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ALK1</name>
        <name evidence="11" type="ORF">MICPUCDRAFT_58004</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058835.1">
        <property type="nucleotide sequence ID" value="XM_003058789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTB1"/>
    <dbReference type="STRING" id="564608.C1MTB1"/>
    <dbReference type="GeneID" id="9684274"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58004"/>
    <dbReference type="eggNOG" id="KOG0580">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HMEVIWN"/>
    <dbReference type="OrthoDB" id="377346at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="221"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="125"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="497"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="705"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="591"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="637"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="664"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="705"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="299"/>
            <end position="301"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="350"/>
            <end position="351"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH57290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="743" mass="79211" checksum="61B162B4FA145249" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTU5</accession>
    <name>C1MTU5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58555</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059381.1">
        <property type="nucleotide sequence ID" value="XM_003059335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTU5"/>
    <dbReference type="STRING" id="564608.C1MTU5"/>
    <dbReference type="GeneID" id="9684545"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58555"/>
    <dbReference type="eggNOG" id="ENOG502QRQT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IMQAHIR"/>
    <dbReference type="OrthoDB" id="10265862at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037695">
        <property type="entry name" value="IQUB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057887">
        <property type="entry name" value="IQUB_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21074">
        <property type="entry name" value="IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21074:SF0">
        <property type="entry name" value="IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25805">
        <property type="entry name" value="IQUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IQ motif and ubiquitin-like" evidence="2">
        <location>
            <begin position="347"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="250"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="499" mass="56492" checksum="12866E54F09CB939" modified="2009-05-26" version="1">MSFHVLAAAIDIKRAIAAELPIPIETMALKAAGAVEGAGAVEGEGEDAAAAAAAAATMRDATTLFDVGVRPGDEAELELVVEYAKPSEEEAEAVDVDPNAPKVLPERIDVVVAPKERGGQPRVVSVVIDASNCEKPRYKGGYRHKHTGTRYHHAEIQTMRKPREWPKDAKFTRDTQTTEARTRTIMTKKEAATQMKRKDLLINENRDAFVSAGRYVDSDEWHAIRVAATTVLQRYARGWFARKLRDVKRVERDERARARAKAATEKLDAEERRRRKEIERRMRPRTHEDFDILRHELEKWRKSEHAKIESDASADDAAKARNKQLLLRRETKLLATIDRLKVTAAAENKDARVARALDDMSTAKRWECDDGSVVEVHTPFTTRAKELQQLYNGVRLPLVTADERLDVLLHVKWTVKEFDCNLTREIVELIDREADLIDRGRDVKTMGGLRRRLSNLFLQFIETPEFNPEAARYSVAAAAAALQEQEKELARSKRTARVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUH7</accession>
    <name>C1MUH7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaphase-promoting complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MICPUCDRAFT_33905</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the APC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059200.1">
        <property type="nucleotide sequence ID" value="XM_003059154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUH7"/>
    <dbReference type="STRING" id="564608.C1MUH7"/>
    <dbReference type="GeneID" id="9684936"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_33905"/>
    <dbReference type="eggNOG" id="KOG1858">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26401at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000211">
        <property type="entry name" value="Anaphase-promoting complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046794">
        <property type="entry name" value="Apc1_MidN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20518">
        <property type="entry name" value="Apc1_MidN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="799"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="831"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="855"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 middle" evidence="13">
        <location>
            <begin position="93"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="192"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="708"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH56332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="910" mass="92735" checksum="81815C4A0D250511" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUM6</accession>
    <name>C1MUM6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_18196</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059223.1">
        <property type="nucleotide sequence ID" value="XM_003059177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUM6"/>
    <dbReference type="STRING" id="564608.C1MUM6"/>
    <dbReference type="GeneID" id="9684663"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18196"/>
    <dbReference type="eggNOG" id="KOG2112">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LEHWFAP"/>
    <dbReference type="OrthoDB" id="2418081at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF17">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="3">
        <location>
            <begin position="17"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="224" mass="23642" checksum="71D9710AC98974C8" modified="2009-05-26" version="1">MSAKYPKPIVVDAPEGGNATAACIFLHGLGDTGHGWADVASQMPFEGVKWIFPTAPTIPITLNGGVRMTGWYDINDLSVEGIVDDREETLASAKYIDSIVDGVVAEGIDPSRIIVGGFSQGGVVALTAALRSDKKLAGCAALSTYLAMRDDYPAALGPHAKSLPVFLAHGTADQVLRYEYGTLTNEKLGALGVSVDFKTYRGMGHSACQEEFQALATFIASCLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV36</accession>
    <name>C1MV36_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_4565</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059303.1">
        <property type="nucleotide sequence ID" value="XM_003059257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV36"/>
    <dbReference type="STRING" id="564608.C1MV36"/>
    <dbReference type="GeneID" id="9684743"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4565"/>
    <dbReference type="eggNOG" id="KOG3689">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WDILVSL"/>
    <dbReference type="OrthoDB" id="541199at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="58"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="288" mass="32505" checksum="C037D18E9AC0FA7C" modified="2009-05-26" version="1" fragment="single">WEYDVLAAAESGGYGLKGIAFEIFHGEGLVDAFAIPHARFKSLLARIELLYSVENPYHCALHAADVLSATHCLRKALPDVFSAVETLALYLAALGHDAGHFRLNNAFLKNSKHTLAKKYPESVLENFHLGLVFELLEDPDVGIVPFLPATDLARFRALLSALILATDMSKHMGLFKELQRWPWVRPALERASEKDRLVVMQLLLKCADLANVVRPLEIADAWGKRIMEEFYQQGEKELSLGLPLTTFPNRRNFDYVFARHQLGFLVNVVRPLFEVFTRLTSFDAREAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVZ5</accession>
    <name>C1MVZ5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plastid-encoded RNA polymerase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_18521</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060124.1">
        <property type="nucleotide sequence ID" value="XM_003060078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVZ5"/>
    <dbReference type="STRING" id="564608.C1MVZ5"/>
    <dbReference type="GeneID" id="9685277"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18521"/>
    <dbReference type="eggNOG" id="KOG1522">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DETKFHF"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="5">
        <location>
            <begin position="23"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH56076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="333" mass="36930" checksum="AB24D0D49BC88C6C" modified="2009-05-26" version="1">MAPTTEPKQRSPSIVVQELTHEKIRFALLHTDTSVANALRRVIIAEVPTLAIDLVDVIENTSCLCDEFIAHRLGLIPLLSEKAVEMEFPYDYAGDDESVTDVHFELNTGICASAETVDVTSNDLVCYDPRVAPVNYHPGESIKGKGGAMEFEAQAAARGPDDGPDIPGVVIVKLRRGQQINMRCVARKGVGRDHAKWQPVATATYRFEPEITINEELMATLTEEEKMAFVESSPTALFRYDEATRRVVVDAPDQARSYGYDGECLKKAEELGKPGLVDIRAKEDAFHFTVESTGALRPEEIVVNALKVLERKMEVTRGELDILEREQDEQVAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW16</accession>
    <name>C1MW16_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_11973</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060136.1">
        <property type="nucleotide sequence ID" value="XM_003060090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW16"/>
    <dbReference type="STRING" id="564608.C1MW16"/>
    <dbReference type="GeneID" id="9685574"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11973"/>
    <dbReference type="eggNOG" id="KOG0242">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FNAMETL"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="4">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH56088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="96" mass="10222" checksum="DFAAECEF3C8352CB" modified="2009-05-26" version="1" fragment="single">LYVVDLAGSERADAHAVRTARADAIKKEGGSINQSLLTLRLCTRAPPPPPTHVPYRDSKLTRILQPALAGPGRTAVVAAINPAPSQMNETHSTLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW36</accession>
    <name>C1MW36_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_59611</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060147.1">
        <property type="nucleotide sequence ID" value="XM_003060101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW36"/>
    <dbReference type="GeneID" id="9685295"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59611"/>
    <dbReference type="eggNOG" id="ENOG502STJ3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DPCVAEN"/>
    <dbReference type="OrthoDB" id="5587706at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11723">
        <property type="entry name" value="YabN_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035013">
        <property type="entry name" value="YabN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="2">
        <location>
            <begin position="59"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH56099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="478" mass="49123" checksum="38DD68B4778DFF1A" modified="2009-05-26" version="1">MATASAAVHGVAPRARARWRRDASRDPVAGHHRASIARASPPTTPSSASMSRPMNKGEIIVVGLGPGNPAQITLEAWSALTADGALVHVRTAKHPTLSGLPAHVALRTFAHVYERTKKLEDVYPTIVKELIDRAVERASEVDEEAADAADASSSSSSSSSSRAIVYAVPGDPCVAENSVNILRAAAPARGVSVRLIPGVSFLEPTLAAVQADLLPSLAVVDAIDAAVSGYAIGISGDAPVLLCQLYSNALASDVKLTLMNQYPEETPVTLVHAAGCDDEIVETLQLCDLDRSEHIDILTSAYIPAIGGVNGVNGAGMESLLDVIVKKRTGGGGGGVGVDGGWLADSAAADGADAGDDPDLEDPDDVSSSSGSFDEAFDSFDFDECIDLECVWSVPDHAEDVAVDALRSAAMNAVAAAASDAPAEVRVDALGKLLAQVGLHVALAVEVGEFAMRDVVAAAIESVRREGTGGDDGEARGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXC2</accession>
    <name>C1MXC2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_69057</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060667.1">
        <property type="nucleotide sequence ID" value="XM_003060621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXC2"/>
    <dbReference type="STRING" id="564608.C1MXC2"/>
    <dbReference type="GeneID" id="9685809"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69057"/>
    <dbReference type="eggNOG" id="KOG1426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QIVEICI"/>
    <dbReference type="OrthoDB" id="496144at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF360">
        <property type="entry name" value="ULTRAVIOLET-B RECEPTOR UVR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="42"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="101"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="159"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="233" mass="24262" checksum="3F74178815784D2B" modified="2009-05-26" version="1">MERPSDEAETTPRLVRSLADDNVRAVSVHAGDAHSACVDEDGTLYVWGSNRYNQLGLGGKENHPRGGDAFVTTPTTVPRLPRVGSFACGGSFSVAANRHGAGLKSWGANGSGELGEGHDAGNESRAAPRAVDTSSVKGSADFVRVSAGWRHAAAIATDGGVYTWGWGGSAGQHHDDAFSTGGQLCLGVDNDFWEPFPVPDFTRRGDGGRRLLAAKDVSCGFNHTVVLVDDGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXI6</accession>
    <name>C1MXI6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60173</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060402.1">
        <property type="nucleotide sequence ID" value="XM_003060356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXI6"/>
    <dbReference type="GeneID" id="9686137"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60173"/>
    <dbReference type="OMA" id="HRRHAHI"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="253" mass="29461" checksum="75639D4CE94BFE78" modified="2009-05-26" version="1">MATLTPQLAKNGGALGGVKMTLAWGKRSIIAKYEEEVAERKRKEAARRERKERRKRRRSGGGGSRERRRTRRRSRSRSRRRSRSRSRSRTRSRSRGRSRSRSRGRSRSRSRGGERDGGKDGDGDGGGDGGGGRRRSRSRSESRSRGRSRRKRKSKRRREKRRKRRRRRRSRSSSSSSSSSGSSESSSSGSSESSSRRRRKKRRRRRSRSRSRERKREKSDEKARSRSRSRSRERKREKSDEKAEDAAAARPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXU0</accession>
    <name>C1MXU0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-uridine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_60288</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a uridine in tRNA + S-adenosyl-L-methionine = a 3-[(3S)-3-amino-3-carboxypropyl]uridine in tRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:62432"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:16092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:82930"/>
            <dbReference type="EC" id="2.5.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TDD superfamily. DTWD2 family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.25" evidence="1"/>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060753.1">
        <property type="nucleotide sequence ID" value="XM_003060707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXU0"/>
    <dbReference type="GeneID" id="9686190"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60288"/>
    <dbReference type="OMA" id="WGNARRM"/>
    <dbReference type="OrthoDB" id="544179at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016432">
        <property type="term" value="F:tRNA-uridine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005636">
        <property type="entry name" value="DTW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039262">
        <property type="entry name" value="DTWD2/TAPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21392">
        <property type="entry name" value="TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21392:SF0">
        <property type="entry name" value="TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03942">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01144">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DTW" evidence="8">
        <location>
            <begin position="136"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH55522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="459" mass="48641" checksum="36B1FCD28BB6F59F" modified="2009-05-26" version="1">MGGASEGGDAPPLPPHSRSARDPDRHTRHVSRAEWRARHPAPPSRSRDRDAPLGKNGGPARGRVVSGVHRTQAELERASPPNLRRMGLNSVEEYFAMEERRIRAKAALDAIVRDPTVPAEEKHHAAATYHVTAGRHIHNCRDCWLMRGLCVCDLLCKVPSARLEPHGVVAYLHHFEWGRGSSTGNLIRACLGGELFVTGERTHERALREMFEGNDGGKNVAILWPGEGSVDVRDVVREASRRSAEALGAGEGNAGEGSVGVGVGGGGGVTFVAVDATWNSARKMMRRIPKHITRARIPPEAFDADYDASKHVASPPPPPPSDAATTKTGSTKTTSLLAPVRKYKNAPDGRCSTFEAVIALMRVLGHDRETCDGLLRAVKTKVDAVLVQKSVPGAYGTFSVEEDVYEAAAAARRAREAMAVGPARGDGGGGGGGEGGDPGVEGGVEGGCWMTAAMAGLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXV5</accession>
    <name>C1MXV5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60304</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060762.1">
        <property type="nucleotide sequence ID" value="XM_003060716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXV5"/>
    <dbReference type="GeneID" id="9685897"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60304"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="103" mass="12310" checksum="DCF3AD426E12A9A4" modified="2009-05-26" version="1">MTYRMRQTCQELVGILPEEEWYEAYVVNGDANGDARTAVCDRKGQACERYPTQKFIDEAWDKEEEEEEEAPRTLFTSMREPEKKKKRKRKRSMPKERAEDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY50</accession>
    <name>C1MY50_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_60402</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060506.1">
        <property type="nucleotide sequence ID" value="XM_003060460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY50"/>
    <dbReference type="STRING" id="564608.C1MY50"/>
    <dbReference type="GeneID" id="9686247"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60402"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH55275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="218" mass="24271" checksum="D2735E0F8464836A" modified="2009-05-26" version="1">MHATLEADGSIACVIFSNLGPNPRDRIALAAVSRVFRDAEKADASLPCGGGLSALKKLGDEFHHSEHKDAEAVYWWRKGADRGDADCMYAIGRCYRHGDHGVEKDRRKSCEWLIKASELGHADSTYFLAVCYQLGEGVDIDEAKAFELNVKAAHSFNLGNLYRHGLCGVAEDKKEALKWFRVAFDIGYDRNYFGSIGFQYLRGICRMLEAELAATRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYA8</accession>
    <name>C1MYA8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59839</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060249.1">
        <property type="nucleotide sequence ID" value="XM_003060203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYA8"/>
    <dbReference type="STRING" id="564608.C1MYA8"/>
    <dbReference type="GeneID" id="9685983"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59839"/>
    <dbReference type="eggNOG" id="ENOG502QVZR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="508259at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33344">
        <property type="entry name" value="OS02G0761600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33344:SF1">
        <property type="entry name" value="OS06G0214100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="375" mass="39172" checksum="796F15625E49107D" modified="2009-05-26" version="1">MALRPVQRIKNRPVTTKLCLCVLLSIFSFTLYRHETSRARAIADAGVGVAAARAAATTAGSARGGASARARAIAALVKAHGVERVEETIAATRASGDGDDAGADDDDAKTTTAKTATPTNATRRVPAAVAVEKTETPSIERAPLAGRTRFVDPLNAVSTPSPARIRACGSPASDAYSSVNASCLLSSPTATSFDATPSARRALIAWIEPRASYDGLAVRWGLGHTVQSAEACAEACREHEPGKAGAEVASLPCNAFAYCPMETPRAQNLNDTMKPKGGGKGDHGGCFEPDAHEHAPGDCWLKFTEAPEAVEVNQARRRGANAGRGFERKRPGGGGGVSYRERHPASPKLVDWTSGVLLPEGWVPSNGTLGPRATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYF5</accession>
    <name>C1MYF5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_68886</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060276.1">
        <property type="nucleotide sequence ID" value="XM_003060230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYF5"/>
    <dbReference type="GeneID" id="9686003"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68886"/>
    <dbReference type="OMA" id="IVEACQC"/>
    <dbReference type="OrthoDB" id="497832at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002128">
        <property type="term" value="P:tRNA nucleoside ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18098">
        <property type="entry name" value="SpoU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="TRNA/RRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786:SF6">
        <property type="entry name" value="TRNA_RRNA METHYLTRANSFERASE SPOU TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="6">
        <location>
            <begin position="313"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="492" mass="52086" checksum="AFD36B3A323C8741" modified="2009-05-26" version="1">MASHAALRASFVGVASASSASRRDPRTPTLRRRRSSPPPPTTTTTTRASSSDASSSPSQHQKVSPSVRRPPPPPGHAEIAIRYAYPGVRFAQGNVVVVSVPNPLDDDDDDDDDDDGAATERVKSKSLDVPASTVTTALASDGVDVVRWRPRVALSLPRGGHGGGGEDADAGWRRLRDDDVISFAHSTGEDAVADGLLVRLEDDLIAATAAPAAANRYAFRSDPTRYTRLEGSKGKVLRGGDEGDDDDKVSGQIKNARESGVTRRAASARGFWKLSDEGVGRVGAGNNPYAGASSDGTSVEPSSDLGAGYFGIGIVKPKHDANVGTLWRSAWQLGAAFIFTVAARYKHKYEASDTTQSHKQLPLHKHDDWGDFAKSSPHGAVLVAIEMGGTPLQDFAHPPRAVYVLGSEDNGLNRPIVEACQCHVALPKWFGRSASYNVAMAGTLVMYDRMIKQLWAGDAKAPSDGDVADAVDDAERADLLFAAAEAAEAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYN1</accession>
    <name>C1MYN1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59962</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060597.1">
        <property type="nucleotide sequence ID" value="XM_003060551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYN1"/>
    <dbReference type="GeneID" id="9686034"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59962"/>
    <dbReference type="OMA" id="NKRNEGS"/>
    <dbReference type="OrthoDB" id="511222at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="117" mass="12590" checksum="676B8DB28F89CB70" modified="2009-05-26" version="1">MPQKALGKGKKIPRLGKKAPAMNRHGKLAKQKKGKFDKKAIVRGANATTDYLNSKTLSAQLNAKNETEAARRATQTGGKMHVVRPPPGTTSEPRGPKSKKQGPVVKMKTKKACGSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYU3</accession>
    <name>C1MYU3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60485</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM228 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061100.1">
        <property type="nucleotide sequence ID" value="XM_003061054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYU3"/>
    <dbReference type="STRING" id="564608.C1MYU3"/>
    <dbReference type="GeneID" id="9686282"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60485"/>
    <dbReference type="eggNOG" id="ENOG502SG3R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="547133at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040046">
        <property type="entry name" value="FAM228"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28584">
        <property type="entry name" value="FAMILY WITH SEQUENCE SIMILARITY 228 MEMBER A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28584:SF1">
        <property type="entry name" value="PROTEIN FAM228B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="553"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="553"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="597"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="612" mass="69868" checksum="3716A3E0272716DD" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZD5</accession>
    <name>C1MZD5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretory pathway family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_4504</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060939.1">
        <property type="nucleotide sequence ID" value="XM_003060893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZD5"/>
    <dbReference type="STRING" id="564608.C1MZD5"/>
    <dbReference type="GeneID" id="9686635"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4504"/>
    <dbReference type="eggNOG" id="KOG0780">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GISDQFQ"/>
    <dbReference type="OrthoDB" id="1727884at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17874">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000053">
        <property type="entry name" value="Signal recognition particle receptor FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="CELL DIVISION PROTEIN FTSY HOMOLOG, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="7">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="340" mass="36451" checksum="128FCAEDBD28E89A" modified="2009-05-26" version="1" fragment="single">RRGGRASRLVVRADGFSIGKLASVLAKKTQADFDRVFKGTSKTREKLSYMDEMLSLWRLEDVEETLDELEEVLISVDFGPTTAMDVIEVVRERVEKGEISTGPQVKQALKTAIVDILQRPNGGEPGCAPLALSEEAPTVIMVVGVNGAGKTTTLGKLSNRFALESGAKVMLVPGDTFRAAAAEQLATWAERSDGVMATYKEGMKPGAVCYQAVQEAIKMGDVDIVLADTSGRLHTNCDLMDELAGVRRSITKSLASAPHETLLVLDGTSGLNMLNQARAFSEAVDVTGLILTKLDGTARGGAVVSVVNEMNIPVKFVGVGEKMEDLQTFEPESFVDAIFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZK9</accession>
    <name>C1MZK9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Carbohydrate-binding module family 45 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">GWD2</name>
        <name evidence="15" type="ORF">MICPUCDRAFT_48104</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061237.1">
        <property type="nucleotide sequence ID" value="XM_003061191.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MZK9"/>
    <dbReference type="GeneID" id="9686411"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48104"/>
    <dbReference type="eggNOG" id="ENOG502QQ6R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LCERRAN"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056301">
        <property type="entry name" value="GWD-like_N_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054481">
        <property type="entry name" value="GWD1_pHisD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46999:SF1">
        <property type="entry name" value="ALPHA-GLUCAN WATER DIKINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46999">
        <property type="entry name" value="ALPHA-GLUCAN WATER DIKINASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22973">
        <property type="entry name" value="GWD1_pHisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23166">
        <property type="entry name" value="Ig_N_CWD1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha-glucan water dikinase-like N-terminal Ig-like" evidence="14">
        <location>
            <begin position="80"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-glucan water dikinase-like N-terminal Ig-like" evidence="14">
        <location>
            <begin position="420"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-glucan water dikinase phosphohistidine-like" evidence="13">
        <location>
            <begin position="1072"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="12">
        <location>
            <begin position="1360"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="18"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="217"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="333"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="455"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="547"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="243"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="345"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="465"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="547"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="563"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH54887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1562" mass="165893" checksum="55FFBD2C034FC96D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZU8</accession>
    <name>C1MZU8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_7941</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061015.1">
        <property type="nucleotide sequence ID" value="XM_003060969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZU8"/>
    <dbReference type="STRING" id="564608.C1MZU8"/>
    <dbReference type="GeneID" id="9686722"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7941"/>
    <dbReference type="eggNOG" id="KOG1454">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6431331at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="7"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="113" mass="12240" checksum="DDC5D2896CF1A8A4" modified="2009-05-26" version="1" fragment="single">EVKPNKVLLVHGAGMCAYTYQKLMRELQKIGYECIAPDLPGHGGTSKPSPSAFKYDSKAYADALEAFIAETDVVINGPCDLVVSGFYTSQHALLLAAKTPELFRRVVVLNAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZX3</accession>
    <name>C1MZX3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_63551</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061294.1">
        <property type="nucleotide sequence ID" value="XM_003061248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZX3"/>
    <dbReference type="STRING" id="564608.C1MZX3"/>
    <dbReference type="GeneID" id="9686468"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63551"/>
    <dbReference type="eggNOG" id="ENOG502QQSA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="APEYACE"/>
    <dbReference type="OrthoDB" id="512200at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058032">
        <property type="entry name" value="CDP1-like_a_solenoid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057137">
        <property type="entry name" value="CDP1-like_a_solenoid_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025344">
        <property type="entry name" value="CDP1-like_IMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044685">
        <property type="entry name" value="CPD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33925">
        <property type="entry name" value="PLASTID DIVISION PROTEIN CDP1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33925:SF1">
        <property type="entry name" value="PROTEIN ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23468">
        <property type="entry name" value="ARC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13355">
        <property type="entry name" value="ARC6-like_IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25515">
        <property type="entry name" value="Arm_PDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid division protein CDP1-like 1st alpha solenoid" evidence="4">
        <location>
            <begin position="172"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Plastid division protein CDP1-like 2nd alpha solenoid" evidence="3">
        <location>
            <begin position="324"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Plastid division protein CDP1-like IMS" evidence="2">
        <location>
            <begin position="666"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH54944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="703" mass="73409" checksum="45FF834C93478C02" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0Q4</accession>
    <name>C1N0Q4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_48241</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061680.1">
        <property type="nucleotide sequence ID" value="XM_003061634.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9686871"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48241"/>
    <dbReference type="eggNOG" id="ENOG502SYZ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1898167at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35830">
        <property type="entry name" value="OS05G0299200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35830:SF1">
        <property type="entry name" value="OS05G0299200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1252"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="864"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1252"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1281"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1310"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1335"/>
            <end position="1349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1349" mass="142548" checksum="FEAEFEEC40650F47" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0V3</accession>
    <name>C1N0V3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51163</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061702.1">
        <property type="nucleotide sequence ID" value="XM_003061656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0V3"/>
    <dbReference type="GeneID" id="9686898"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51163"/>
    <dbReference type="OMA" id="ASIHEYC"/>
    <dbReference type="OrthoDB" id="189770at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007914">
        <property type="entry name" value="UPF0193"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28348">
        <property type="entry name" value="UPF0193 PROTEIN EVG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28348:SF1">
        <property type="entry name" value="UPF0193 PROTEIN EVG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05250">
        <property type="entry name" value="UPF0193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="289" mass="32697" checksum="793FB86DDFF334E9" modified="2009-05-26" version="1">MPRRDDDDDDDAETMWDVLGRGTAAGRAVFNLYAPGDVTGKRYGRLMSDYNVAKLQVRHASDPSKRRAPPHVEETLKREARVASSKRANQRVNVPTPTGRRAMTEEEEEAFKFEAAKRATVCRKTEAEIRAKMEKDKPWERPPPRPSRRLIGEEGKLRHQRMVEFDGRPPEEEGERRGYVPPPGLEKADAAAAAAAAAAARAPPPPPPRRRTGETETEVQQIETLRAMFDDVANEIEEREVFMNEMRAAGAGRKHEHSVKAEIAERVSQLRRIDAMIRDLEASIHEYCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>C1N144</accession>
    <name>C1N144_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_51256</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061505.1">
        <property type="nucleotide sequence ID" value="XM_003061459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N144"/>
    <dbReference type="STRING" id="564608.C1N144"/>
    <dbReference type="GeneID" id="9687185"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51256"/>
    <dbReference type="eggNOG" id="KOG0554">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PRFPGQC"/>
    <dbReference type="OrthoDB" id="1931232at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04318">
        <property type="entry name" value="EcAsnRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000016">
        <property type="entry name" value="Asparagine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000738">
        <property type="entry name" value="WHEP-TRS_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003037">
        <property type="entry name" value="PRK03932.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF54">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, CYTOPLASMIC 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51185">
        <property type="entry name" value="WHEP_TRS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WHEP-TRS" evidence="10">
        <location>
            <begin position="252"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="350"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH54135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="592" mass="64956" checksum="22F056346116D076" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1A5</accession>
    <name>C1N1A5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_51325</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061778.1">
        <property type="nucleotide sequence ID" value="XM_003061732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1A5"/>
    <dbReference type="STRING" id="564608.C1N1A5"/>
    <dbReference type="GeneID" id="9686974"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51325"/>
    <dbReference type="eggNOG" id="ENOG502QPTI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TVCEREM"/>
    <dbReference type="OrthoDB" id="498485at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="entry name" value="Ribosomal protein L25, beta domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_bL25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_bL25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_bL25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_bL25_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_uL5_bac-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33284">
        <property type="entry name" value="RIBOSOMAL PROTEIN L25/GLN-TRNA SYNTHETASE, ANTI-CODON-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33284:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L25_GLN-TRNA SYNTHETASE, ANTI-CODON-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910582" evidence="5">
        <location>
            <begin position="24"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL25 L25" evidence="6">
        <location>
            <begin position="65"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL25 beta" evidence="7">
        <location>
            <begin position="165"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="254" mass="27578" checksum="0BA287C62C6E5EA1" modified="2009-05-26" version="1">MQRHVARAVARWGLALNAAPTLAGDLALRQPATTTAVVGGFASTFVRRAGTFGKDTSKDKGDVIDVRLRDASGRIAAKKLRKEGRVPAILFRSGSRAGEHISLALKDIERLVTKHGHVGVGTRVLKMRFEGTDRAEDVIAKQVHLTMGTGVVENATFMPVEPTTEVNVDVPVTFIGEDVCPGVKQGGFPWVMRRSVPVKCQVKDIPRVFNIDVSNFSVGKVVFLKDLHVPESVKLRLDNMMTPVFSMSRPGRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1B2</accession>
    <name>C1N1B2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flagellar radial spoke protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RSP6</name>
        <name evidence="6" type="ORF">MICPUCDRAFT_63054</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ropporin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061537.1">
        <property type="nucleotide sequence ID" value="XM_003061491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1B2"/>
    <dbReference type="STRING" id="564608.C1N1B2"/>
    <dbReference type="GeneID" id="9687221"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63054"/>
    <dbReference type="eggNOG" id="ENOG502QTNR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MQERIYC"/>
    <dbReference type="OrthoDB" id="10067602at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22985">
        <property type="entry name" value="DD_CrRSP11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003117">
        <property type="entry name" value="cAMP_dep_PK_reg_su_I/II_a/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14952:SF9">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14952">
        <property type="entry name" value="ROPPORIN-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02197">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00394">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2 6" id="KW-0969">Cilium</keyword>
    <keyword evidence="2 6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIIa" evidence="5">
        <location>
            <begin position="18"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="211" mass="22259" checksum="C2CA6EF7B6299282" modified="2009-05-26" version="1">MPLDLDPIYCAEQIAVPPDLADVLKAYTKEVVRRQPADVYAFSADYFANLADVTAVPPEDTSAPTVHQLADAYSAVKGKGELSAADFESVCVGAGVPRATVQRAFRLGEFGSTAPVKPSEPLTLLLTMTDASFVGICASLFDVFGEDGKLTGVEFLALFAYLTAKDPSVTQESLDALETALGDKVNEKLSFGEANARVADVLAAIMDEGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1F3</accession>
    <name>C1N1F3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_63086</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061807.1">
        <property type="nucleotide sequence ID" value="XM_003061761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1F3"/>
    <dbReference type="STRING" id="564608.C1N1F3"/>
    <dbReference type="GeneID" id="9686993"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63086"/>
    <dbReference type="eggNOG" id="KOG0998">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NANGDEH"/>
    <dbReference type="OrthoDB" id="524326at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="2">
        <location>
            <begin position="95"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="128"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="654" mass="69050" checksum="5C5C1D1673C58B37" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1T6</accession>
    <name>C1N1T6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein translocase subunit SecA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_45843</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O + chloroplast-proteinSide 1 = ADP + phosphate + chloroplast-proteinSide 2.</text>
            <dbReference type="EC" id="7.4.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061969.1">
        <property type="nucleotide sequence ID" value="XM_003061923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1T6"/>
    <dbReference type="STRING" id="564608.C1N1T6"/>
    <dbReference type="GeneID" id="9687615"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45843"/>
    <dbReference type="eggNOG" id="ENOG502QS62">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VQPNRRW"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016464">
        <property type="term" value="F:chloroplast protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17928">
        <property type="entry name" value="DEXDc_SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1440.10:FF:000003">
        <property type="entry name" value="Preprotein translocase SecA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000429">
        <property type="entry name" value="Preprotein translocase subunit SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3060.10">
        <property type="entry name" value="Helical scaffold and wing domains of SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1440.10">
        <property type="entry name" value="SecA, preprotein cross-linking domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612:SF11">
        <property type="entry name" value="PROTEIN TRANSLOCASE SUBUNIT SECA2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21090">
        <property type="entry name" value="P-loop_SecA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="Helical scaffold and wing domains of SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="Pre-protein crosslinking domain of SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="9 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SecA family profile" evidence="15">
        <location>
            <begin position="1"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="63"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="396"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH53681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="893" mass="99931" checksum="C7A7D5ED1831CB79" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1U2</accession>
    <name>C1N1U2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_70009</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061972.1">
        <property type="nucleotide sequence ID" value="XM_003061926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1U2"/>
    <dbReference type="STRING" id="564608.C1N1U2"/>
    <dbReference type="GeneID" id="9687412"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70009"/>
    <dbReference type="eggNOG" id="KOG1808">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5186at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103:SF2">
        <property type="entry name" value="MIDASIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103">
        <property type="entry name" value="MIDASIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="87"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="391"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="657"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="701"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="669"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="707"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="731"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="741"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="888" mass="93184" checksum="B2907F2E47DD15A4" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1N243</accession>
    <name>C1N243_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor SYF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_7978</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">May be part of a spliceosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SYF2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062025.1">
        <property type="nucleotide sequence ID" value="XM_003061979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N243"/>
    <dbReference type="STRING" id="564608.C1N243"/>
    <dbReference type="GeneID" id="9687465"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7978"/>
    <dbReference type="eggNOG" id="KOG2609">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DHECREY"/>
    <dbReference type="OrthoDB" id="199717at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013260">
        <property type="entry name" value="mRNA_splic_SYF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264">
        <property type="entry name" value="GCIP-INTERACTING PROTEIN P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08231">
        <property type="entry name" value="SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH53737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="186" mass="21730" checksum="3C475EB96BD8ADCE" modified="2009-05-26" version="1" fragment="single">EAPEEYEKMQKKKSYDAAAKRRDEERVKQGIDPSKKHLMMTAEEAAVSYKKKQKKYKTAVGGEIHSKHNLYQAYDKRTKNIQVNEQEYETMKNTVGERAFYADPEVAAYGGEGKVAPDAVDRMVAELEEQKRKRLDFSRRRKYYEERDVSHINDRNAHFNKKIERAFGEHTKEIKANLERGTALPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N297</accession>
    <name>C1N297_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">formate C-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_44800</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>formate + acetyl-CoA = pyruvate + CoA</text>
            <dbReference type="Rhea" id="RHEA:11844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.54"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.54" evidence="3"/>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062051.1">
        <property type="nucleotide sequence ID" value="XM_003062005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N297"/>
    <dbReference type="STRING" id="564608.C1N297"/>
    <dbReference type="GeneID" id="9687694"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_44800"/>
    <dbReference type="eggNOG" id="ENOG502QSG9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CAKVSIE"/>
    <dbReference type="OrthoDB" id="10256780at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008861">
        <property type="term" value="F:formate C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050244">
        <property type="entry name" value="Auton_GlycylRad_Cofactor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30191">
        <property type="entry name" value="FORMATE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30191:SF0">
        <property type="entry name" value="FORMATE ACETYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000379">
        <property type="entry name" value="For_Ac_trans_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51998">
        <property type="entry name" value="PFL-like glycyl radical enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0556">Organic radical</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFL" evidence="11">
        <location>
            <begin position="1"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="10">
        <location>
            <begin position="653"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="9">
        <location>
            <position position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH53763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="776" mass="83613" checksum="B9BE94BE835252F7" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2D4</accession>
    <name>C1N2D4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_51487</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061855.1">
        <property type="nucleotide sequence ID" value="XM_003061809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2D4"/>
    <dbReference type="STRING" id="564608.C1N2D4"/>
    <dbReference type="GeneID" id="9687301"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51487"/>
    <dbReference type="eggNOG" id="KOG0740">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MVQLRTH"/>
    <dbReference type="OrthoDB" id="3046016at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052267">
        <property type="entry name" value="N-DRC_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14690">
        <property type="entry name" value="IQ MOTIF CONTAINING WITH AAA DOMAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14690:SF0">
        <property type="entry name" value="IQ MOTIF CONTAINING WITH AAA DOMAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="3">
        <location>
            <begin position="777"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="442"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="608"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="658"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="382"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="473"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="613"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1036" mass="114490" checksum="8E6AA6CFFA692513" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2H4</accession>
    <name>C1N2H4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51529</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061872.1">
        <property type="nucleotide sequence ID" value="XM_003061826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2H4"/>
    <dbReference type="STRING" id="564608.C1N2H4"/>
    <dbReference type="GeneID" id="9687529"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51529"/>
    <dbReference type="OrthoDB" id="419768at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052981">
        <property type="entry name" value="Ingression_C2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052">
        <property type="entry name" value="CONSERVED SERINE PROLINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_2G01790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052:SF3">
        <property type="entry name" value="INGRESSION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="91" mass="10249" checksum="F2E32AE20DD2F326" modified="2009-05-26" version="1">MANSRGKLEVNVLRAWGLKDTQTFGTQDPYCVVRVNDQRARTRVSVDGGTSPAFHERLTMDVFGHPPHVFVEVRSIHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2R3</accession>
    <name>C1N2R3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_48386</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061921.1">
        <property type="nucleotide sequence ID" value="XM_003061875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2R3"/>
    <dbReference type="STRING" id="564608.C1N2R3"/>
    <dbReference type="GeneID" id="9687569"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48386"/>
    <dbReference type="eggNOG" id="ENOG502R392">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10260961at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42103:SF2">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42103">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="123"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="359" mass="37463" checksum="F0E46ECEC41C4FAD" modified="2009-05-26" version="1">MGQCQSVCTSKTAPGSPREKDDRGLEPSSSGAGGGKNPASVLNLGKEAEMYFAKGGKVWYQKCPTTPADAADETAVEEEKLNIKSSDGVVLRAILARPATPSSPNASLDGVAVVMCHPHPFIGGGMHNPLMVNVSRRLAAAGTTTLRFDFRGVGASTGKRTWMRQGEQDDVLACARYLTRLQGVDPTRVYVAGYSFGASVALGALDQERSDHVAGFVGISYPFGVKAMLIPGGGKCRSEKPKLFLVASGDVMCKDGEKGAEAEIATLPKPTETVRVDTGHGWSGRHAAVARIILEWLESVRGGGGGGGKGSNEGSSSEGSTPGGSRNNSAKSLKLRAGGSGNLRSESKRSQPQRFGRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1N384</accession>
    <name>C1N384_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_48530</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062565.1">
        <property type="nucleotide sequence ID" value="XM_003062519.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N384"/>
    <dbReference type="GeneID" id="9688005"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48530"/>
    <dbReference type="eggNOG" id="KOG0029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GWHWANL"/>
    <dbReference type="OrthoDB" id="496653at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141052">
        <property type="term" value="F:histone H3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF410">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIRM" evidence="8">
        <location>
            <begin position="39"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="9">
        <location>
            <begin position="162"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="409"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="603"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="690"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="812"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1209"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1130"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="421"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="616"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="817"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="840"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="857"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1209"/>
            <end position="1218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH53384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1375" mass="146331" checksum="34DCAB1291BB416E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>C1N491</accession>
    <name>C1N491_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P-type Ca(2+) transporter</fullName>
            <ecNumber evidence="2">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_36018</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="2"/>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062749.1">
        <property type="nucleotide sequence ID" value="XM_003062703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N491"/>
    <dbReference type="STRING" id="564608.C1N491"/>
    <dbReference type="GeneID" id="9688398"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_36018"/>
    <dbReference type="eggNOG" id="KOG0202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VCCGQFD"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000014">
        <property type="entry name" value="Calcium-transporting ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000077">
        <property type="entry name" value="ECA1 (ER-TYPE CA2+-ATPASE 1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000065">
        <property type="entry name" value="Sarcoplasmic/endoplasmic reticulum calcium ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="331"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="869"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="994"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="15">
        <location>
            <begin position="27"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH52688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1079" mass="114222" checksum="25313DA1EA72C12C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4C6</accession>
    <name>C1N4C6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">riboflavin kinase</fullName>
            <ecNumber evidence="2">2.7.1.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_8520</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="2"/>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062977.1">
        <property type="nucleotide sequence ID" value="XM_003062931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4C6"/>
    <dbReference type="STRING" id="564608.C1N4C6"/>
    <dbReference type="GeneID" id="9688205"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8520"/>
    <dbReference type="eggNOG" id="KOG3110">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NGEVHKM"/>
    <dbReference type="OrthoDB" id="276388at2759"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749:SF6">
        <property type="entry name" value="RIBOFLAVIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Riboflavin kinase" evidence="8">
        <location>
            <begin position="2"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH52916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="138" mass="15237" checksum="59D44959B2C8562C" modified="2009-05-26" version="1" fragment="single">RAPVVYGFGRGSKKMGVPTANLDPDVLEEELGSMRKGVYFGYARLPADEKHAAWTKCVVNVGSRPTFADGDGVTVETHALRDYGRDFYGEDMEVVVVGYLRPEMKFDGMAALVNRIMTDIGLARNALDDPGHRRRADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4H6</accession>
    <name>C1N4H6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_21836</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="9">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062792.1">
        <property type="nucleotide sequence ID" value="XM_003062746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4H6"/>
    <dbReference type="STRING" id="564608.C1N4H6"/>
    <dbReference type="GeneID" id="9688440"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21836"/>
    <dbReference type="eggNOG" id="KOG3196">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IMSIYPE"/>
    <dbReference type="OrthoDB" id="10254187at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902494">
        <property type="term" value="C:catalytic complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098796">
        <property type="term" value="C:membrane protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000022">
        <property type="entry name" value="NADH dehydrogenase flavoprotein 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1590:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01958">
        <property type="entry name" value="nuoE_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371:SF3">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01257">
        <property type="entry name" value="2Fe-2S_thioredx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="185"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH52731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="245" mass="26892" checksum="A8BA75E4EE5B99F0" modified="2009-05-26" version="1" fragment="single">SQHRDTPTNNDALKWDFTEANAPLVREILERYPPNYKRSAMIPLLDVAQQQNGGYLSVQVMNRVAEILEVAPIRVFEVATFYSMFNRQPVGKYHVMVCGTTPCMLRGSREVNAALEQHLGIKKFENTPDGMFTLGEMECMGSCVNAPMIAVADYTNGVEGYTYNYYEDLTPADAVAVVKALKAGQKPRVGSQHRDKAEPMGGQQTLTSEPPGPYCRDLNKARADLEAAAKAAAEAAAAAEKEKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N594</accession>
    <name>C1N594_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_52857</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062928.1">
        <property type="nucleotide sequence ID" value="XM_003062882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N594"/>
    <dbReference type="GeneID" id="9688572"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52857"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912382" evidence="1">
        <location>
            <begin position="24"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="184" mass="19553" checksum="26A0B33F8E7D6251" modified="2009-05-26" version="1">MRATALVLAALVAAAACVSGANAAPDDASTRWGNTHHDSKLFDKDGDVASARIAYADAARGYARAKHDAAMSRVDAAHEHFKSAMTAALAALGDAAAAWHAHATETREALAEHARDSVEKTKAHVDDAREKMRSHVDDAHDAHRARAAKVADAASEHVAKWTGKDDADNRRVLYTGPHTTAFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5B0</accession>
    <name>C1N5B0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_52876</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062936.1">
        <property type="nucleotide sequence ID" value="XM_003062890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5B0"/>
    <dbReference type="GeneID" id="9688580"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52876"/>
    <dbReference type="eggNOG" id="ENOG502S80E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ACWAREC"/>
    <dbReference type="OrthoDB" id="41867at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="426" mass="46913" checksum="65F1705AD1D75853" modified="2009-05-26" version="1">MLRRTPTTSTSNVGQSGPGHNVSTREARPTGRMRPRRRARAARPTPTPTPTPTPTPSSRDDDRPPPAASSSSFASLPTSLARRFVALAAWKRFALITLVVAGPYALYVSYLWIRLQSGLLRAPVRVATPRAVLIVGTQSSGTTQMSAELGKIGLEVAHETSDAQWEFARDGTISWLHALRFMPGRADLAFTTAFCSRFRRSMGFHPAMFGPPELGCSYRKTWDDCWRTQCGVIARREWGCARSGSCETPFETSLLQLRHPLRTMESLAAKFCGRAVMVGSGLSAPNHLARPNPEFIEIVAALWPERDDWHSLACADAMGWYVALYTRDMLNARDEGVIAEAYRVEDTPPCAVAKMSGLLQRSERAAARCDAYWASVAASGEEGAPTRKGRNRRNRDGIVRLSMRDVESEELRALVTDVANRSGYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5F2</accession>
    <name>C1N5F2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_42869</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063544.1">
        <property type="nucleotide sequence ID" value="XM_003063498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5F2"/>
    <dbReference type="STRING" id="564608.C1N5F2"/>
    <dbReference type="GeneID" id="9688791"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42869"/>
    <dbReference type="OrthoDB" id="2422440at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011124">
        <property type="entry name" value="Znf_CW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46245">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN OS07G0563300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46245:SF2">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION REPRESSOR VAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07496">
        <property type="entry name" value="zf-CW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51050">
        <property type="entry name" value="ZF_CW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CW-type" evidence="4">
        <location>
            <begin position="16"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="149" mass="16653" checksum="4B3615B6F670ED7D" modified="2009-05-26" version="1">MAPSTYSDALRALLSPLTSDQWVQCDSCEIWRRVPKRIADALGDDEQWFCNLNPYDYFNRCDAPQEIEDDEIDVVLQAQAAAEEYKLAAVERAAAEKAEKAAAAAAAAAREHVSYNMSVTDGNQTRRQFQARSIHWSPYDRVGVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5N5</accession>
    <name>C1N5N5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_22347</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063395.1">
        <property type="nucleotide sequence ID" value="XM_003063349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5N5"/>
    <dbReference type="GeneID" id="9688834"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22347"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="62" mass="6339" checksum="F37AEE60641EAA7C" modified="2009-05-26" version="1" fragment="single">MLAPVGAANQHPKCVDDSGLCGPDFGGRVCDAGRYCVGGMCRADDKCGPDHGNTICPGNRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5S4</accession>
    <name>C1N5S4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53020</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063415.1">
        <property type="nucleotide sequence ID" value="XM_003063369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5S4"/>
    <dbReference type="GeneID" id="9688647"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53020"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="140" mass="15216" checksum="184212AA1D933C3E" modified="2009-05-26" version="1">MSSFARTATPANALKAIDSKQKHLRMLLCDRLETNAETYGDGAAMPGRRVLAATTEGGRESDEQDDATTTTEADARDDDDDDDDDDASLDPKYWFPPYAKRGALARDLSTAVSRGRTPTGDFVETINPALHPPPGNGFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5X9</accession>
    <name>C1N5X9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_45929</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063235.1">
        <property type="nucleotide sequence ID" value="XM_003063189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5X9"/>
    <dbReference type="STRING" id="564608.C1N5X9"/>
    <dbReference type="GeneID" id="9688881"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_45929"/>
    <dbReference type="eggNOG" id="KOG1475">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DYLEFEN"/>
    <dbReference type="OrthoDB" id="10259785at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025755">
        <property type="entry name" value="Ribos_uL4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013000">
        <property type="entry name" value="Ribosomal_uL4_euk/arc_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_uL4_euk/arch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14374">
        <property type="entry name" value="Ribos_L4_asso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00939">
        <property type="entry name" value="RIBOSOMAL_L1E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL4 C-terminal" evidence="4">
        <location>
            <begin position="271"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="396" mass="42754" checksum="A17AB1143A38CF73" modified="2009-05-26" version="1">MPAALPTVTVQNGNGATCQLPEVFLSPIRPDIVNAVHTGLNKNNRQAYAVFNKAGHQTAAESWGTGRAVSRIPRVPGGGTHRAGQGAFGNMCRGGRMFAPTKTWRRWHRRVNLKQKRYAVCSALAASAVPALLMARGHAVETVPEVPLVVGDDVESIAKTAKAVALLKSIGAYADVEKVKESRNIRSGKGKMRNRRYVQRRGPLVVYADDDGITKAFRNIPGVELCSVDRLGLLTLAPGGHVGRFIIWTKKAFEKLDAVFGTAAAASSAKKGWKPPRSIMTVPDLSRVINSDEIQSAVNAPKAGKTRAHAPLKRNPLKNKAAMERLNPYAKVAAQMAAAAEKERSAAKAKKVAGARSKVGEAFYQGMKSDSAYEGELFDNFAEWLHGKPEEEEEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5Z2</accession>
    <name>C1N5Z2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_63808</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPPP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063447.1">
        <property type="nucleotide sequence ID" value="XM_003063401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5Z2"/>
    <dbReference type="GeneID" id="9688683"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63808"/>
    <dbReference type="OMA" id="YEAFATH"/>
    <dbReference type="OrthoDB" id="10645960at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001578">
        <property type="term" value="P:microtubule bundle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032273">
        <property type="term" value="P:positive regulation of protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008907">
        <property type="entry name" value="TPP/p25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932">
        <property type="entry name" value="P25 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932:SF9">
        <property type="entry name" value="TUBULIN POLYMERIZATION-PROMOTING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05517">
        <property type="entry name" value="p25-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="31"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="644"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="654"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="696" mass="72941" checksum="47692350FBD579C4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6D2</accession>
    <name>C1N6D2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_53244</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063318.1">
        <property type="nucleotide sequence ID" value="XM_003063272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6D2"/>
    <dbReference type="STRING" id="564608.C1N6D2"/>
    <dbReference type="GeneID" id="9688951"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53244"/>
    <dbReference type="eggNOG" id="ENOG502QT9C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ACDALWG"/>
    <dbReference type="OrthoDB" id="3191556at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000045">
        <property type="entry name" value="4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527">
        <property type="entry name" value="4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="6">
        <location>
            <begin position="150"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="23"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH52454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="382" mass="40514" checksum="C2402557147672F8" modified="2009-05-26" version="1">MSRVLPAAVPRATARDVSRARRAPSSPSVRGGRNVRSSHLAASASRASSTVSMTTTTTRRRAVNGAGVVAAAASASSLDAAPSDATSFFSPSKINLFLRVVRRRDDGYHDLASLFHVIDLGDDMKFALSSSTTRDTLVCDDDTIPLDDSNLVIKALNLWREKTGSEQRFWVELKKNVPHGAGLGGGSGNAATAMWAANDLCGKPASEADLLLWSGDIGSDISVFFSTGAAYCTGRGEIVEDVDPPLPLDTPILLVKPNVGLSTPAIFKALDLDGRSAEDPLGLLEKIKAEGPKDSICVNDLEAPAFSKLPELLELKKRLKADGGDGVKSVFMSGSGSTIVQIGDDDVPGFVADDDALFRAKTRLITRKKGEWYAPSPFLEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6E0</accession>
    <name>C1N6E0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53252</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063320.1">
        <property type="nucleotide sequence ID" value="XM_003063274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6E0"/>
    <dbReference type="GeneID" id="9688957"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53252"/>
    <dbReference type="OrthoDB" id="10690614at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTF2" evidence="2">
        <location>
            <begin position="13"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH52456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="65" mass="7195" checksum="C044374E93C2B5C5" modified="2009-05-26" version="1">MAPPSSNRALRVVARAFVGAYYRDLNDAPDRVARYYTEDSVFALEDGTTPRKERRKRAAGASSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6K9</accession>
    <name>C1N6K9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_6775</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063565.1">
        <property type="nucleotide sequence ID" value="XM_003063519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6K9"/>
    <dbReference type="STRING" id="564608.C1N6K9"/>
    <dbReference type="GeneID" id="9689006"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_6775"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CENAGMS"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="3">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="227" mass="23208" checksum="358CD1BC8F160300" modified="2009-05-26" version="1" fragment="single">AHAMDPQQRRLLTWTSRALSDAKLETPQRSTEEPLVGVYVGAATTDYGKLASDADATPSATAATGSAFLSVTAGRCAFTLNTRGPAIAIDTACSSGLVATHAARAAIDRREDDRGDARRRQLQVVAGVNFLLHRSTTAMFHAAGMLAPDGRCKSLDASADGYVRGEACCRAVSLKGTSASASANASFDGPGDAVVVVGGAGVNQDGRSSSLTAPNGPSQQAVIRAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1N751</accession>
    <name>C1N751_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_53557</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063673.1">
        <property type="nucleotide sequence ID" value="XM_003063627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N751"/>
    <dbReference type="STRING" id="564608.C1N751"/>
    <dbReference type="GeneID" id="9689114"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53557"/>
    <dbReference type="OrthoDB" id="550206at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="27"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH52046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="68" mass="7586" checksum="4E02116136AAD97D" modified="2009-05-26" version="1">MFSFQDAGENEKNANADAKTGAKVRTCGRCDARDVSWRACGGCRKTYYCGKECQRADWPSHKETCKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N787</accession>
    <name>C1N787_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53594</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063694.1">
        <property type="nucleotide sequence ID" value="XM_003063648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N787"/>
    <dbReference type="GeneID" id="9689296"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53594"/>
    <dbReference type="OrthoDB" id="10594019at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912345" evidence="1">
        <location>
            <begin position="25"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="129" mass="13548" checksum="E7704AB1CF74E524" modified="2009-05-26" version="1">MPRLLLAAAAVACVLFATPPTALAAELECPTIDVDTQNSVAVACLGDDEGLCGEQCFSAIRDAALARSDDVEIACGDGLDDVLEQVKGCMKREAGLDWVDCDGRNVQRIVDYADKIKCEGGGTLADKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7E4</accession>
    <name>C1N7E4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49020</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063885.1">
        <property type="nucleotide sequence ID" value="XM_003063839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7E4"/>
    <dbReference type="GeneID" id="9689162"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49020"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="414" mass="44760" checksum="39409DC11E32DB18" modified="2009-05-26" version="1">MELKLEEADEDAAEMLRGVENVGGKSPARRRAPVVSGGLTSGAGGPGATGGMGRRRSVNMNMTSRRLSVNANAAHGSPARRRLSTTHHGRRDSDGTRRLSVTSVASDDFGDARGRRRDSVNSAHRGGGTRRLSTSSALSVETAGLPPAAALEPEFHWQPLHRVTVARDLPLELFESDDDDDALDPKVIEMETKLRNEGVIELSSVADAAAPVGAEVSAHKDMYSGHGAFTGGVRSGGPSRRVSVASAHGGGGDACIAEEEMSDEIAMEIALKRRRDAAELARRYDFDVATARKASDVAETRALRPFFHGPSPPEVVKPPPKDASLRKHRYGDWFLPSATRAKKAYEAALERYLEKIGGPLATEARLTRLRKEKIARTIAPLYATTQYRAYLRENPGTGVPHYMREKKTKKTKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7P3</accession>
    <name>C1N7P3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_49052</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064129.1">
        <property type="nucleotide sequence ID" value="XM_003064083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7P3"/>
    <dbReference type="STRING" id="564608.C1N7P3"/>
    <dbReference type="GeneID" id="9689383"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49052"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NTIGYMY"/>
    <dbReference type="OrthoDB" id="509488at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="458"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH51751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="529" mass="58838" checksum="CC671FCBF10F2EAE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Z3</accession>
    <name>C1N7Z3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_53885</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064179.1">
        <property type="nucleotide sequence ID" value="XM_003064133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Z3"/>
    <dbReference type="STRING" id="564608.C1N7Z3"/>
    <dbReference type="GeneID" id="9689433"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53885"/>
    <dbReference type="OMA" id="LVINMET"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH51801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="243" mass="24819" checksum="7D85D7165849486B" modified="2009-05-26" version="1">MEPPAVGGGGGSHYYVALPDPRAKPRALADLVVNVALAAARQTSSDRSIARGETNRKPAVVAVVVVRDARDGVDDAVEDIARAGKDVARVDDRADVVVASLRADQPPGDRADALERFRAARRREDGETFSTTFARGGVFALVTSEACLPSPGAGEGALGASLVINMETPKSREAYARRTRAGLGGGGRAGGGGGGGVVVLNVIAPHQLSALRAVLPDGVALDAMPIDLIDTLAADVAAGGRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N805</accession>
    <name>C1N805_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_66259</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064186.1">
        <property type="nucleotide sequence ID" value="XM_003064140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N805"/>
    <dbReference type="STRING" id="564608.C1N805"/>
    <dbReference type="GeneID" id="9689438"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66259"/>
    <dbReference type="eggNOG" id="KOG0937">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DYGYIQN"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09253">
        <property type="entry name" value="AP-4_Mu4_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14838">
        <property type="entry name" value="AP4_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="6">
        <location>
            <begin position="221"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH51808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="508" mass="54470" checksum="D286BA87734302F1" modified="2009-05-26" version="1">MISQLFILSPRGDVIIKKEYRHDVPKTSPETFFRAVRFWKDAERAPAVFAEDGVHYLHVKANGLFLATTTRKNVSPSHVLELLHRVAKVIKDYCGVMNEDALRKNSVLAYELLDEMIDRGYAQSTSTEALKRHVFNEPSTPASSATTGAGAAAARASAAVKRASTPYGVFKGVVKAGIEYGKEAAAAKAAPTHTPGGTARRDATQRSVLATARDKARGGSRNEIFVDVVEKISVCFAASGATLTSEVDGCVQIRNFLHGSPEIKLALPEDLAIGGRDFATAVGGDYGFGSGGASGMATLLDDCNFHESADLSNFDVDRTIALTPPEGEFSLMNYRASCDFDPPFKVRVTVDETTPYKITAVITIKATYPSKCACTGMVVKFPTPQRAINANPTLEPGATPGTQHAAFSSQDKAVTWQFKKFTGGAEHTLRVNVSIPEERLPNARKELGPVSMHFTIPMFNVSRVGVRYLQIGGGSSGGGAGAGAQGKGKGPHRWVRYVTKSSSYVCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1N837</accession>
    <name>C1N837_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53934</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064012.1">
        <property type="nucleotide sequence ID" value="XM_003063966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N837"/>
    <dbReference type="GeneID" id="9689453"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53934"/>
    <dbReference type="eggNOG" id="KOG1134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DTHAMWL"/>
    <dbReference type="OrthoDB" id="1689567at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF114">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="490"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="563" mass="60031" checksum="101BD8E4678FB997" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N846</accession>
    <name>C1N846_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_66277</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064206.1">
        <property type="nucleotide sequence ID" value="XM_003064160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N846"/>
    <dbReference type="STRING" id="564608.C1N846"/>
    <dbReference type="GeneID" id="9689459"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66277"/>
    <dbReference type="eggNOG" id="ENOG502SBEM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910680" evidence="2">
        <location>
            <begin position="31"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="424" mass="45202" checksum="448F88062B4F90F6" modified="2009-05-26" version="1">MAGGRRRAAAVAALGAAAVLSLCAYGASKAYTKGFWAGVDWCADETARRMRDAARATSSSDGGDDDDDDDDDDARTRERRQRRARRDAAPSAETPGSVSDAVEIASPATASPSPSPSRASASKMKKKTAATSTAPPPPLPTPPPPRARPTPPAPPPAPARRSPVDIAAGYVAVYDDMRAAFDASGFDAIAATTSRRWFRFDPPPAVGVWPPPYVSLHLPKDCARLVAFTLEESPAVAAAAAAAAREVFSVLGKAGIPAFNVSRSSFHVSVFFLSLPEEPIDDPFTARIAGAAGSGTSSSFDLNSFEPDHEREEKTLEKTLRGVVDGGAIELEVDRVQMASRRQTHIAHSTLLRAFPSAPEEDGEREGSDGRRERVRDAAARGVSAACERWSARIEGVKVRVNEAWFVREERFSSLDGARCSFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1N855</accession>
    <name>C1N855_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_8342</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064023.1">
        <property type="nucleotide sequence ID" value="XM_003063977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N855"/>
    <dbReference type="STRING" id="564608.C1N855"/>
    <dbReference type="GeneID" id="9689651"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8342"/>
    <dbReference type="eggNOG" id="KOG3100">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TWVEELM"/>
    <dbReference type="OrthoDB" id="427886at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="3">
        <location>
            <begin position="7"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH51645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="103" mass="11972" checksum="953D0EFC5D193D37" modified="2009-05-26" version="1" fragment="single">KKLGRGDAGRGWFNMPAVEYTPELRRDLRLLKLRGAYDPKRFYKTEDTTKLPKHFQVGTVIEGAQDFYSARLTKRARKNTLTEEIAADAEIKTVRKKRFAKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1N956</accession>
    <name>C1N956_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_54370</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NSE2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064559.1">
        <property type="nucleotide sequence ID" value="XM_003064513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N956"/>
    <dbReference type="STRING" id="564608.C1N956"/>
    <dbReference type="GeneID" id="9689837"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54370"/>
    <dbReference type="eggNOG" id="KOG2979">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="THEIKTH"/>
    <dbReference type="OrthoDB" id="26899at2759"/>
    <dbReference type="UniPathway" id="UPA00886"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16651">
        <property type="entry name" value="SPL-RING_NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026846">
        <property type="entry name" value="Nse2(Mms21)"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330:SF1">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="256"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH51464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="294" mass="31049" checksum="B191DC0F595FDFB2" modified="2009-05-26" version="1">MAAATEPPLALDAAGVKHAIGAAANAPLPEYEAFDDDFDETLDLFAEVAEACETNGRSSDAVRARSLVVVVVVARVLANAKKLVAMHREHASHRKALAHLRENYACSLDATDFAAVLDATAKSLLESDAPYREKIADLERKIAAARRKAKAGGAANRDGGDGSDGSDEDVDVVVTQAGRPGDFDCPNLKCPLTQLLIKDIATPVVDQKGYVYEKDAVMDYIARYKNPRTGRAECPQAGTNHEIRSEDLKPARAIERARKRAKALADGGGGGGGGGRKRGSMGGGRSDAEDLISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9A8</accession>
    <name>C1N9A8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_54429</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064421.1">
        <property type="nucleotide sequence ID" value="XM_003064375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9A8"/>
    <dbReference type="STRING" id="564608.C1N9A8"/>
    <dbReference type="GeneID" id="9689862"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54429"/>
    <dbReference type="eggNOG" id="ENOG502S3RX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CANRAAT"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34123">
        <property type="entry name" value="OS04G0578200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34123:SF1">
        <property type="entry name" value="OS04G0578200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="299" mass="31468" checksum="C6A91EC9C8B852AE" modified="2009-05-26" version="1">MAASLVTAAAAARVARCDGASASAGATRTTTLRGGRSRFGASSSAHRFRRVRLSPIVAASSSSADDDEDTAARTATATATAAERSKYEETSGAVKALVSGLTAIVNAVGSVTSSSSSGSNDGAKLTRKERRDARPFPSSPRDATALRDDIAREFTEAKYLWTGDINPEMYDLFCTFTDPTLSFAGLQTFETNLKNLQPVLRRLVRNSNVELYSCEIVDDGSGGSGGGSGGGGGGSVRASWRMTGDLNLPWRPRIDLTGQTTFGFKDAGVERGCLIVSYLEEWGISALDAVAQLVAPFKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9X3</accession>
    <name>C1N9X3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_49302</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064809.1">
        <property type="nucleotide sequence ID" value="XM_003064763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9X3"/>
    <dbReference type="STRING" id="564608.C1N9X3"/>
    <dbReference type="GeneID" id="9690131"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49302"/>
    <dbReference type="eggNOG" id="KOG2017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MQDPSFF"/>
    <dbReference type="OrthoDB" id="498241at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052204">
        <property type="entry name" value="PpiC/parvulin_rotamase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43629">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43629:SF2">
        <property type="entry name" value="RHODANESE-LIKE_PPIC DOMAIN-CONTAINING PROTEIN 12, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13616">
        <property type="entry name" value="Rotamase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="4">
        <location>
            <begin position="73"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="5">
        <location>
            <begin position="189"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="31"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH51143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="280" mass="30229" checksum="0F1F473434A2CA3F" modified="2009-05-26" version="1">MMLLRSSTPRVVARAVGATFSSSATTASRASSSAIPAMIPRRRQRHRRVSPWVTRTFASSSSSSSSSSAPPHEGQIKIAHILMDASDEAQLDELYERVVAGADDLATLAAEYSKCPSGKANGGLIGWIGRGQTVKPFEDAAFATPIGGVTRAKTTFGVHVVQVLDQREAPAAVVNVSVEDLAEVLEVGDLDGVNLVDVREEDEWRATRIDAFTLMPLSKVMQMTEAEWDEKLAGVDKSKPTYMLCKAGVRSAHAGKEFASRGFKEVYNVMGGMDAWGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAF9</accession>
    <name>C1NAF9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54886</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064901.1">
        <property type="nucleotide sequence ID" value="XM_003064855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAF9"/>
    <dbReference type="GeneID" id="9690341"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54886"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH50881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="91" mass="10066" checksum="F51BD2492BE4B62B" modified="2009-05-26" version="1">MVTRLKHLLIFPSPRTVYLFMNLKLPTRPNARHSLVTTLIIKQIPGLEHATISGDWSIKDNANGTIVAPHHVCAYVNACTDVDGNGPEFNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGI5</accession>
    <name>C1MGI5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_23938</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054780.1">
        <property type="nucleotide sequence ID" value="XM_003054734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGI5"/>
    <dbReference type="STRING" id="564608.C1MGI5"/>
    <dbReference type="GeneID" id="9680319"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23938"/>
    <dbReference type="eggNOG" id="KOG0896">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NWSREST"/>
    <dbReference type="OrthoDB" id="6508832at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23807">
        <property type="entry name" value="UEV_UBE2V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000026">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="11"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="150" mass="16639" checksum="EF8CC071EB9672D0" modified="2009-05-26" version="1">MAAAGDTVVVPRNFRLLEELEKGEKAQGASPHLSYGLADPEEDAMMINWNGTIIGPNGTPFEGRIYSLQIECGESYPELPPIVKFRTRVNLPCVSGDHGRVNPAAVPVMAQWRRSYTIEDVLNSLWNLMKSPQCRKLGQPPETAPDYPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGN0</accession>
    <name>C1MGN0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_12326</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054805.1">
        <property type="nucleotide sequence ID" value="XM_003054759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGN0"/>
    <dbReference type="STRING" id="564608.C1MGN0"/>
    <dbReference type="GeneID" id="9680308"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_12326"/>
    <dbReference type="eggNOG" id="KOG1691">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MAIRGIF"/>
    <dbReference type="OrthoDB" id="1929172at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="9">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="182" mass="20170" checksum="5AE6109E3E745B7F" modified="2009-05-26" version="1" fragment="single">RCVDEELGANVLVLMSYESADGAAVDVRVTDPDGRDVYVAKNKARGKAGFTTKIAGDHSACFTRSRPPGGGDDFSSNDGDGVAHRVKLDWKKGVAVNDWNKIAKRGDVADVATDLRRVEADLRGVHQEMMWLRRREEEMRTINEKTNARVAWLCAMSLCACVASGATQYAYLKYHFRAKKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MH22</accession>
    <name>C1MH22_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LHCA5</name>
        <name evidence="8" type="ORF">MICPUCDRAFT_50023</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055418.1">
        <property type="nucleotide sequence ID" value="XM_003055372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MH22"/>
    <dbReference type="STRING" id="564608.C1MH22"/>
    <dbReference type="GeneID" id="9680476"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50023"/>
    <dbReference type="eggNOG" id="ENOG502S0ZD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EFRPIPW"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH60670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="254" mass="27367" checksum="E29D0A35397A021C" modified="2009-05-26" version="1">MAAMLRAPLGVNTVRAVAPKVAQKRSVRSFAVVNGDRIGVMGHWLPGTEPPSYLDGTMPADYGFDPLRLGANPETLPYLQEAELMNGRWAMHATAGILFTDAVGLPKFWEAGEAALGDWDLKTLVAIQVVVMGFLEAARIRGFMATGESGVVGNFPFDPTGQDSPAMKVKEVKNGRLAMMSFLGMVSQYAVTGTSPLEGLKAHMANPTGVNIFTSSVGGEFTAFVCALSLMPVYFLFQKEVSDGEDEEFRPIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHT9</accession>
    <name>C1MHT9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Polyadenylate-binding protein</fullName>
            <shortName evidence="8">PABP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_46263</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds the poly(A) tail of mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the polyadenylate-binding protein type-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055549.1">
        <property type="nucleotide sequence ID" value="XM_003055503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHT9"/>
    <dbReference type="STRING" id="564608.C1MHT9"/>
    <dbReference type="GeneID" id="9681098"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46263"/>
    <dbReference type="eggNOG" id="KOG0123">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DHMNGKE"/>
    <dbReference type="OrthoDB" id="19742at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12378">
        <property type="entry name" value="RRM1_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12379">
        <property type="entry name" value="RRM2_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12380">
        <property type="entry name" value="RRM3_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12381">
        <property type="entry name" value="RRM4_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000003">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000217">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000648">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006515">
        <property type="entry name" value="PABP_1234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002004">
        <property type="entry name" value="PABP_HYD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034364">
        <property type="entry name" value="PABP_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045305">
        <property type="entry name" value="RRM2_I_PABPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01628">
        <property type="entry name" value="PABP-1234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00658">
        <property type="entry name" value="MLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00517">
        <property type="entry name" value="PolyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51309">
        <property type="entry name" value="PABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="32"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="120"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="209"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="313"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="11">
        <location>
            <begin position="525"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="431"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH60801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="606" mass="64962" checksum="C1229FD8616A191E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHU5</accession>
    <name>C1MHU5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U3 snornp-associated-like WD40 repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_50325</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055016.1">
        <property type="nucleotide sequence ID" value="XM_003054970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHU5"/>
    <dbReference type="STRING" id="564608.C1MHU5"/>
    <dbReference type="GeneID" id="9681120"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50325"/>
    <dbReference type="eggNOG" id="KOG0299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CSLRIWK"/>
    <dbReference type="OrthoDB" id="189968at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039241">
        <property type="entry name" value="Rrp9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="190"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="294"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="572" mass="60984" checksum="169E7D1E1F7FD766" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI30</accession>
    <name>C1MI30_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_50415</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055594.1">
        <property type="nucleotide sequence ID" value="XM_003055548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI30"/>
    <dbReference type="STRING" id="564608.C1MI30"/>
    <dbReference type="GeneID" id="9680785"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50415"/>
    <dbReference type="eggNOG" id="KOG4813">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NDYEDFM"/>
    <dbReference type="OrthoDB" id="498076at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.60">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023194">
        <property type="entry name" value="eIF3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013906">
        <property type="entry name" value="eIF3j"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08597">
        <property type="entry name" value="eIF3_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="176"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH60846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="224" mass="24450" checksum="EBABF696523482C6" modified="2009-05-26" version="1">MSDLDWDDDEFEVPDLAKDEPPKKANVFDEEEEEDEAPVIKKPSAKPAPAKKKAAEYVDETLADPVAEKLRRQKLVEEADLEAAKELFGTDGEEIDLGTYAPKSEKEFVKFGTLVATKYLTPFKTSAFYKEAIKSFVKSATKTMSAAEVKEVEAAIVAIRNDKVKSEKAESAAAAKAASASATTTGSGKKKKFLNQGGKGGDSGLEDYKYDTKGGNYDDDYDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI88</accession>
    <name>C1MI88_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50479</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055084.1">
        <property type="nucleotide sequence ID" value="XM_003055038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI88"/>
    <dbReference type="STRING" id="564608.C1MI88"/>
    <dbReference type="GeneID" id="9681023"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50479"/>
    <dbReference type="eggNOG" id="KOG3146">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VEATLNW"/>
    <dbReference type="OrthoDB" id="302705at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047874">
        <property type="term" value="F:dolichyldiphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF40">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE EPSILON 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="262" mass="26661" checksum="FB3ABC9ACFD02755" modified="2009-05-26" version="1">MSSSSSSSSSATTRGAPRARAAAAAPSAGDPPASICEVSAGGGDVQSDGAKARGGGVLAALNESTKFVVSALALVALLRYPNVSTCWCILGSVVNSINGKLLKKLLNHERPTGAVKADPGMPSSHATSLSYLSVYAAAAMLTHGDKMSPVLPAWAVAPTACGVVGCGVFLTWLRVHLGFHTTPQVVVGYALGASTAVGWLCAMERVVGPALRASPKLVGGLRVALAVAVGVFALSAIRWVDEARAYLTREKSLGDKADSSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIF5</accession>
    <name>C1MIF5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_50548</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055120.1">
        <property type="nucleotide sequence ID" value="XM_003055074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIF5"/>
    <dbReference type="GeneID" id="9681214"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50548"/>
    <dbReference type="eggNOG" id="ENOG502SBD7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WPSKRAP"/>
    <dbReference type="OrthoDB" id="276276at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03671">
        <property type="entry name" value="NUDIX_Ap4A_hydrolase_plant_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022927">
        <property type="entry name" value="RppH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43046">
        <property type="entry name" value="GDP-MANNOSE MANNOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43046:SF14">
        <property type="entry name" value="MUTT_NUDIX FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="31"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="195" mass="20899" checksum="48A73229CD3B0CE8" modified="2009-05-26" version="1">MATASEGAGSASAKTERVYPEECRVEMNGKQYRRCAAALVFNKNGDVLVGERSDRPGSWGMPQGGIEVTETAEAAATRELYEEIGVRVGDAATGLRFVASIPPSDEYCYLAGGWLAKKGLAGQRLEFSLFHLPTTEDPAAFCDLRGLDGEPAEFSRVKWARFAEVIDSVWESKRGPYLAASEAAAPIIAACLSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIL5</accession>
    <name>C1MIL5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_13041</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055687.1">
        <property type="nucleotide sequence ID" value="XM_003055641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIL5"/>
    <dbReference type="STRING" id="564608.C1MIL5"/>
    <dbReference type="GeneID" id="9681187"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13041"/>
    <dbReference type="eggNOG" id="ENOG502QR65">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WTGIVST"/>
    <dbReference type="OrthoDB" id="191568at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090415">
        <property type="term" value="F:7-hydroxymethyl chlorophyll a reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033354">
        <property type="term" value="P:chlorophyll cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007516">
        <property type="entry name" value="Co_F420_Hydgase/DH_bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045220">
        <property type="entry name" value="FRHB/FDHB/HCAR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007525">
        <property type="entry name" value="FrhB_FdhB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31332">
        <property type="entry name" value="7-HYDROXYMETHYL CHLOROPHYLL A REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31332:SF0">
        <property type="entry name" value="7-HYDROXYMETHYL CHLOROPHYLL A REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04432">
        <property type="entry name" value="FrhB_FdhB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04422">
        <property type="entry name" value="FrhB_FdhB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal" evidence="2">
        <location>
            <begin position="126"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal" evidence="3">
        <location>
            <begin position="210"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH60939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="524" mass="55392" checksum="D26E1C4E08D10DD5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIP2</accession>
    <name>C1MIP2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50641</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055165.1">
        <property type="nucleotide sequence ID" value="XM_003055119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIP2"/>
    <dbReference type="GeneID" id="9680723"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50641"/>
    <dbReference type="OMA" id="TWYARVR"/>
    <dbReference type="OrthoDB" id="498805at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="277" mass="29001" checksum="01125E172EC04A3F" modified="2009-05-26" version="1">MMMRISTTKCILMTRIVDASNLAPPSSRAAPLRTARVADDFAREKHASEPRIASHRASMAAPDRGPKLPPDARGGKGDASGKKHKSTKSGGGVKTKKRTSSSDGAMKPLVLLAAGMALVPVIKKLKDLLESRGGGEKGEKSEKGSAFSFGKGKRGGKAKGKGGDGGGDAGIKKPPGAGAKGVERVGNVPRNKASNNKKNRARKAERKASRAEEEDRANPKHKAGQLPNGGHAVVKEGNNVPKDDDIIGGEAGKTFTTTSSVKVPTWYARVREERGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIU6</accession>
    <name>C1MIU6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50699</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055725.1">
        <property type="nucleotide sequence ID" value="XM_003055679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIU6"/>
    <dbReference type="STRING" id="564608.C1MIU6"/>
    <dbReference type="GeneID" id="9680512"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50699"/>
    <dbReference type="eggNOG" id="ENOG502SSKU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AHPANIT"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="226"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="120"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="296" mass="30273" checksum="ADBB755664764BDF" modified="2009-05-26" version="1">MRAHAGPRARCAPSARTITPSARAGPRAAATRDRGGGRGDGSTLGAAATRRRGKITIGDVDDAIRARDDASSRGAPERIARDVEAEDDAIGTLRAATRAGVVSVLAAALMSSACPGRALADASEPSTSSSSLASSSSAASSTPPPGDDAASTATAPPPEAAAGPSDAARLPNPPPPLSASAPLPSEVKKQAKAMADDAARDGVAAGGDAGRKESSKEKRANRLEELNVLRVELDTKELELREAAQELLRREQTTAVLTEELELSRRLNDVLSAELNRVREEGKLSVGLCAQGLGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJ07</accession>
    <name>C1MJ07_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61775</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055752.1">
        <property type="nucleotide sequence ID" value="XM_003055706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJ07"/>
    <dbReference type="GeneID" id="9680374"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61775"/>
    <dbReference type="OMA" id="RINCRYA"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH61004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="314" mass="34111" checksum="C89931B9F6B61DB8" modified="2009-05-26" version="1">MIILRRRGSILFSLLISGLFVPVGPAVRYFTASNFSPFASRINRWSSFGFAIFPATPISSPGSPPSFGMTQSGHASVYPSQNAAGFVTSASPGCSDTRRPGSTRRSSRTPSPPCRGSPSACCSSRTRTRRTDARPRLSGTWRPRSPPRWTRSRRRKGCTRPRPPCSDLPRPRGDRASAFAATTVARTRRRAHRVASRHRRRAGRGGGGGGGGGAVRGGGGDDDRGRSRSHLRRECDERSRGRRDGGGLRRLGARGRRAIDARGRGVDGERERHASVQNSRVGGAARVRCAVGMYRINCRYARSEIQPAQRKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJB9</accession>
    <name>C1MJB9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_50883</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH61057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055805.1">
        <property type="nucleotide sequence ID" value="XM_003055759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJB9"/>
    <dbReference type="STRING" id="564608.C1MJB9"/>
    <dbReference type="GeneID" id="9680750"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50883"/>
    <dbReference type="eggNOG" id="KOG1091">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF337">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="1"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="465"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="507"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH61057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="542" mass="56746" checksum="D21CCE26BF7FED87" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJK5</accession>
    <name>C1MJK5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46461</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056228.1">
        <property type="nucleotide sequence ID" value="XM_003056182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJK5"/>
    <dbReference type="GeneID" id="9681621"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46461"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="481"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="385"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="481"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="510" mass="52660" checksum="42F981A450ACC36F" modified="2009-05-26" version="1">MPIHPAQKPWDASPGTRDRAERAIAVGRDRASANEALRASVAALRARGDEVPRRASPRASIAPPARSPRTPRASSSSSSSRHRDRYRALGPGATEKLRALRAVLSSSSPRDGDGDDDDDDDDDDDDRFRFPSSSTPPPPSSRPRASAGGSVFRPPDASRVERLERLERAGAGAGPTPPLATARRRAAAAPRASAPAPAAAGGRAPAGGSTRRAAAVTAERALEEVLIDATRVAREAADARARIRALERALGIARDAVARDRDGGVRGGGGAAADVFSSRVQGGSGRARGSGSGSGSGPGSARVDDATARELATAIAHARAREREMFRVVEDAAKALSDAERDRRVLVTLVPIRPRRRGERRLSTPLLTRPRTPPRRRFACANALRAAAANRATESERRARDAERRCEEEAARAAALERELATRVARGGGGGGGGGRDEDGVRGGRGLAFAASSGAGAGAAAVGRRPPPTPSAAYATLARKLAASGGGSSSSSAAAAPGLVRALDRGRWPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJZ1</accession>
    <name>C1MJZ1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_46507</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056297.1">
        <property type="nucleotide sequence ID" value="XM_003056251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJZ1"/>
    <dbReference type="STRING" id="564608.C1MJZ1"/>
    <dbReference type="GeneID" id="9681905"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46507"/>
    <dbReference type="eggNOG" id="ENOG502RYX4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PSMEFIA"/>
    <dbReference type="OrthoDB" id="2014244at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040703">
        <property type="entry name" value="LCIB/C_CA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38016:SF1">
        <property type="entry name" value="LIMITING CO2-INDUCIBLE PROTEIN B_C BETA CARBONYIC ANHYDRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38016">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18599">
        <property type="entry name" value="LCIB_C_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Limiting CO2-inducible protein B/C beta carbonyic anhydrase" evidence="1">
        <location>
            <begin position="95"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="378" mass="41239" checksum="BD2A6A1B2702AEFC" modified="2009-05-26" version="1">MAISMSAAFGSVASLRADVKTRRGARTSVVVVRASGRTAGFKNNARTKHDSYNEHHGPEYMKHAGLDTLPDERARRHAYYDKRTANVQHHFRGSIGMDDWLFRVENKLAQFGFTGDNTIAHTNFCRDEITAPLKNGIHEMFGYAMDVDGLAGFTAAGLTGLGAGMSHSPTEWQTGKERYVFFAMPHIAVDSAGNPGDCIRAGRAGCSHACGALIKLQPKFTELRAGGMQIRPVGSCDAMDPEYSLLESRMLRAVQPSEVPAEGFDLVQVTKLADSVIQQDMEALVRASVDPGKADFAVVTGVQIHSYGHTLDEWHPNMEYICPTSMYVVVNGQRHDINLLEDCPPPAPRQLFALRGGDVVLETPESMPPAVGTYHAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKS5</accession>
    <name>C1MKS5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dymeclin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_55441</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dymeclin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056438.1">
        <property type="nucleotide sequence ID" value="XM_003056392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKS5"/>
    <dbReference type="STRING" id="564608.C1MKS5"/>
    <dbReference type="GeneID" id="9681727"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55441"/>
    <dbReference type="eggNOG" id="KOG2225">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MATIWLA"/>
    <dbReference type="OrthoDB" id="10253409at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019142">
        <property type="entry name" value="Dymeclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12895">
        <property type="entry name" value="DYMECLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12895:SF9">
        <property type="entry name" value="DYMECLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09742">
        <property type="entry name" value="Dymeclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0519">Myristate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH59814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="453" mass="49598" checksum="A0412C808B22FC47" modified="2009-05-26" version="1">MVPSSFDRFTRRAQPAVSYASVLEACCAHLDGETAPRTTPFARRASFLKDFSRRHSSPSLSFQRGSPSPAVLLLYALLHGNDAFRAYVLGDAARLSKVLTPTLRGLYDASKRESYKEKTVSDGDGVGAAGKKSSHDVTYVLLVIVLILTQDDAFGDALSNALIPVGPNWYEERMLRRTPLGSLLVLVLVRTVHRHLAGSEPLRDVYLHTNCLAAMANVAPRLRGLTAFASRRLVTLFETLSRKRARALARELENSSDLVSGNASNAAFSDAEDDEIELYADFMRIVLEIINSVLTYALPDNPELVYALLHRAELFDAHTEHPRFADLVGNVRGVLNHFSDGIHRGVGGECAKGEGEGEGAAAGQNANAAARGEGMPMTTKEVMCVVNTLAKKFRADSHVHVFQELRFAYEEEADPAAFFSPFLWRLVVEDVGRARSATRWGESFTKMVVDGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKX0</accession>
    <name>C1MKX0_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor, chloroplastic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosome-releasing factor, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RRF</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_70809</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for the release of ribosomes from messenger RNA at the termination of chloroplastic protein biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056070.1">
        <property type="nucleotide sequence ID" value="XM_003056024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKX0"/>
    <dbReference type="STRING" id="564608.C1MKX0"/>
    <dbReference type="GeneID" id="9681738"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70809"/>
    <dbReference type="eggNOG" id="KOG4759">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PNNDQQL"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000001">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome recycling factor" evidence="6">
        <location>
            <begin position="84"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="245" mass="27374" checksum="5376291DC5E66BC4" modified="2009-05-26" version="1">MTTSIADAVSRFQCSPAFKALDYTRVGASIRCIAARKQCAVFHAKRSFIRNSRAVTCAVQENKTPFDIEQSADDRMEKSVDSIRNNLNTVRTGRANAAILDRIEVEYYGSVTPLKSLANITTPDAQTIIIQPFDKNIIDDVEKAIMSSDLDLMPGNDGNCIRLNIPPLTAERRRDLAKLVSKLGEDGKVALRNVRRDTLRSIGKLKGYSEDEIKSLENNVEKMTLKHTTDVDEVVRKKEDEISKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML22</accession>
    <name>C1ML22_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ll-diaminopimelate aminotransferase chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_55549</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056098.1">
        <property type="nucleotide sequence ID" value="XM_003056052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML22"/>
    <dbReference type="STRING" id="564608.C1ML22"/>
    <dbReference type="GeneID" id="9681752"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55549"/>
    <dbReference type="eggNOG" id="KOG0257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SKTFNMT"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009862">
        <property type="term" value="P:systemic acquired resistance, salicylic acid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000099">
        <property type="entry name" value="LL-diaminopimelate aminotransferase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01642">
        <property type="entry name" value="DapL_aminotrans_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019942">
        <property type="entry name" value="DapL/ALD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03542">
        <property type="entry name" value="DAPAT_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43144">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="113"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH59474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="450" mass="48574" checksum="B8ECCACE0305FA57" modified="2009-05-26" version="1">MFTAVSRIDTPAPFFGGNRLVARRAASYTTGRRVVQVHAVTNVSRNPNMGKLKAGYLFPEINRIKNAHLEKKPDAAIISLGIGDTTEPIPAPIIDGMISSVSGLGTPAGYAKYGGYGPGEGQAELREKIASRFYPGGEVSADEIFVSDGSKCDISRLQMLFGPNRNVAVQDPSYPAYVDSSVMNGHATSFDASTKQYGNITYLSCNSNNNFFPNLAHANDSEIIFFCSPNNPTGAAATREQLTDLVAHAKENGSIIIYDAAYASYIENPDCPKSIFEIPGADECAIETCSFSKYAGFTGLRLGWTVVPENLKFADGFSVKADWNRLMNTTFNGASNVAQAGGLACLSDEGWNAMTELVGFYKENASILKRTFEDMGYTTYGGTNAPYVWVSFDGQDSWEVFTEILEKCDIVVTPGSGFGPAGDGFIRASAFGHRDSILEATERLKKAFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML39</accession>
    <name>C1ML39_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_49464</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056107.1">
        <property type="nucleotide sequence ID" value="XM_003056061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML39"/>
    <dbReference type="STRING" id="564608.C1ML39"/>
    <dbReference type="GeneID" id="9681556"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49464"/>
    <dbReference type="eggNOG" id="ENOG502S2ND">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MWTRNAK"/>
    <dbReference type="OrthoDB" id="271080at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033558">
        <property type="entry name" value="IFT25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33906">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33906:SF1">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="134" mass="14693" checksum="646905586957F198" modified="2009-05-26" version="1">MTDISAGASIVMASCADERHLPEDALDPSEQKYWVTDGCYPAELVIKLARPSKVSKLRTSTRGVRKFSLHVCADERLDAGGEFKPVFEVELADKPADAAQVESHKVSVKRALFLKIRVESGWGDFSSVHAVSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1ML43</accession>
    <name>C1ML43_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome b5 domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_64806</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Radial spoke stalk protein that binds heme under oxidizing conditions. Required for the coordinated beating of multiple cilia maybe by functioning in a redox signaling pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056492.1">
        <property type="nucleotide sequence ID" value="XM_003056446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1ML43"/>
    <dbReference type="STRING" id="564608.C1ML43"/>
    <dbReference type="GeneID" id="9681557"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64806"/>
    <dbReference type="eggNOG" id="KOG0537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DLTHFFH"/>
    <dbReference type="OrthoDB" id="260091at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052320">
        <property type="entry name" value="Cytochrome_b5_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21281">
        <property type="entry name" value="CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21281:SF0">
        <property type="entry name" value="CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="10">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH59868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="230" mass="26385" checksum="79912813F8D5806A" modified="2009-05-26" version="1">MFSQVATHSFPDDCWVSIHGNVFNVTNVVLDSLGSWSHLLRKEAGTDISRWFVNCSAGNLDHMTANLDLSVKVNVDPVMNIHHPYFIDSSVLIDAPSTNVDTDAIVPIPWWEDESLIIGRLTSLARKVRLRNVLTGQEHILEVPKEEKVSGIRERYLEYNWHARSYTWKVLRKTCVVGKVHVDFIELDMNKTLDENDVLDDSEIFDELSVPSDFFTPVIHLYYNDDLSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLB9</accession>
    <name>C1MLB9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histone RNA hairpin-binding protein RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_55661</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SLBP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056536.1">
        <property type="nucleotide sequence ID" value="XM_003056490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLB9"/>
    <dbReference type="STRING" id="564608.C1MLB9"/>
    <dbReference type="GeneID" id="9682022"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55661"/>
    <dbReference type="eggNOG" id="KOG3934">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="265795at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071204">
        <property type="term" value="C:histone pre-mRNA 3'end processing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071207">
        <property type="term" value="F:histone pre-mRNA stem-loop binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1120:FF:000001">
        <property type="entry name" value="Histone RNA hairpin-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1120">
        <property type="entry name" value="Histone RNA hairpin-binding protein RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026502">
        <property type="entry name" value="SLBP1/SLBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029344">
        <property type="entry name" value="SLBP_RNA_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038294">
        <property type="entry name" value="SLBP_RNA_bind_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17408">
        <property type="entry name" value="HISTONE RNA HAIRPIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17408:SF0">
        <property type="entry name" value="HISTONE RNA HAIRPIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15247">
        <property type="entry name" value="SLBP_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Histone RNA hairpin-binding protein RNA-binding" evidence="3">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="165" mass="19092" checksum="83DEF67B7F7F5FF1" modified="2009-05-26" version="1">MDRSRLVLRRKQLDLGYNTIGYARYVQLVPRGRRSTNLRRHPRTPDPLRDCSKRSFDGQIRRWRRLLHQYDNICSDEKGVEEITALQAESRPLYAGSLSTELSTFPHQLLVTEKTARRSYYATSCMYNVSEANSNKLTYCLILGNSLAVARKTQKFTNQSCVTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLD9</accession>
    <name>C1MLD9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TGS</name>
        <name evidence="9" type="ORF">MICPUCDRAFT_55679</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056548.1">
        <property type="nucleotide sequence ID" value="XM_003056502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLD9"/>
    <dbReference type="STRING" id="564608.C1MLD9"/>
    <dbReference type="GeneID" id="9681582"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55679"/>
    <dbReference type="eggNOG" id="KOG2730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CSTEGHY"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="8">
        <location>
            <begin position="4"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS01159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="322" mass="36132" checksum="B2AC700D15C8E32C" modified="2009-05-26" version="1">MTHWHQAYDFCYLQFYYYCRCTQISTWLPPAEGFAPLTYSDMCLRFSTTCAAMDSCHMHNRVRFSSSCGKYWVQRRRILSLYDFGVNLDPEAPEIIANHQASRCLHSLHRQSSHRLSPASDGSGMADSQSRSKSSTEFVVLDLFCGAGGNTIAFARCAGARVLACDINETRLDMADKVSLIYGVQHSINFVCNDANAFLNCLRLFSREGAGCYDDVENVEKVDMIFLSPPWGGPGYSIVDSFDIRNIHASGIDVIALIKLSFCLTTNIALYLPKNTDLLPFYCSRALFVNQAPCSFEVEKNYLNGKLKAITLYFGELNMLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLJ7</accession>
    <name>C1MLJ7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL35</name>
        <name evidence="4" type="ORF">MICPUCDRAFT_49485</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056178.1">
        <property type="nucleotide sequence ID" value="XM_003056132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLJ7"/>
    <dbReference type="STRING" id="564608.C1MLJ7"/>
    <dbReference type="GeneID" id="9682042"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49485"/>
    <dbReference type="eggNOG" id="KOG3436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VMNQKAR"/>
    <dbReference type="OrthoDB" id="528635at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00427">
        <property type="entry name" value="Ribosomal_L29_HIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.310:FF:000002">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3450:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_uL29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045059">
        <property type="entry name" value="Ribosomal_uL29_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH59554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="123" mass="14083" checksum="313044F946173904" modified="2009-05-26" version="1">MVGFKVHELRTRSKGDLLNQLKELKTELAALRVAKVTGGAPNKLSKIKVVRLSIAQVLTVIRQNQLQNLREAYAGKKYVPLDLRTKKTRAIRRRLLSADKNVKTSKEAKKYAYFPERKYAMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLS7</accession>
    <name>C1MLS7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_15619</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057274.1">
        <property type="nucleotide sequence ID" value="XM_003057228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLS7"/>
    <dbReference type="STRING" id="564608.C1MLS7"/>
    <dbReference type="GeneID" id="9682253"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_15619"/>
    <dbReference type="eggNOG" id="KOG4280">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QFFRTCG"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000080">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF29">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="6">
        <location>
            <begin position="23"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="111"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="394" mass="43324" checksum="06A3037BD8984E4F" modified="2009-05-26" version="1" fragment="single">MVHPHGGQPRAGGGEAAIGGSSAVKVVVRVRPLNQNELARGEQNSVEVTEDQRALRVHYPDSNGHFQMREFAFNACLATDATQADVMTKCGVPRLLDSALKGYSSTIFAYGQTGSGKTFSMSGREEVISEREYRGASPDTDGIISRSLAHIYQTINRIPGVTHVVKCDYLEIYNEQIYDLLAGNDVQLHERWEPQRGFHVPGLQTIECERLDDAREIIRQGMLNRAVGSHELNKDSSRSHSIFTVHIESIAEVGGQELVKHGKIAFVDLAGSERLKDSKSEGGMVKETANINRSLFMLGKVIATLAEGKAGTTHVPYRDSKLTKLLMDSLGGSSLALMVACCSPSPLHVEETMSTLHYATRARNIINRPTVAQDPQQQLISRLKDECETLRKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLV1</accession>
    <name>C1MLV1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">15-cis-phytoene synthase</fullName>
            <ecNumber evidence="3">2.5.1.32</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PSY1</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_32317</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 (2E,6E,10E)-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34475"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="EC" id="2.5.1.32"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.32" evidence="3"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057282.1">
        <property type="nucleotide sequence ID" value="XM_003057236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLV1"/>
    <dbReference type="STRING" id="564608.C1MLV1"/>
    <dbReference type="GeneID" id="9682269"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32317"/>
    <dbReference type="eggNOG" id="KOG1459">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KLYCYRV"/>
    <dbReference type="OrthoDB" id="6600518at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046905">
        <property type="term" value="F:15-cis-phytoene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:geranylgeranyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000004">
        <property type="entry name" value="Phytoene synthase chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31480">
        <property type="entry name" value="BIFUNCTIONAL LYCOPENE CYCLASE/PHYTOENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="433" mass="48470" checksum="53527764530156E4" modified="2009-05-26" version="1">MASTSVASAQSARVSGVCSVSGRGDIAVARAASRASRRAPSPVSVSGAALRGHKSNRGASANDRHRASRAPSSRVVTRSIMEPETTSASTTFERSPEQVVASNGREVEQFALECCVKRQTSGERVPRPRVPEKMLDDAYERCNEVTSEYAKTFYLGTKLMTPEKQRAIWAIYVWCRRTDELVDGPNASHITPEALNQWEARLEAVFDGRPADVIDAALCDTVSRFPVDIQPFRDMVDGMRMDLVKPRYETFDELYEYCYRVAGTVGLMSMPIMGCDENFEGDLRKVYKAALSLGLANQLTNILRDVGEDVITRNRIYIPLEELRRFGIEESEVIKCSLVDAETGAVDPRWKEFMKFQIARAREVFAEAEAGVNCLHKDARWPVWSALDVYRNILDAIEANDYDNFTQRAYVPKLQKFLMLPAAYSKAQPAMTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMK6</accession>
    <name>C1MMK6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_14767</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056945.1">
        <property type="nucleotide sequence ID" value="XM_003056899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMK6"/>
    <dbReference type="STRING" id="564608.C1MMK6"/>
    <dbReference type="GeneID" id="9682861"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_14767"/>
    <dbReference type="eggNOG" id="KOG0418">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HWTFVYA"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000037">
        <property type="entry name" value="ubiquitin-conjugating enzyme E2 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="8">
        <location>
            <begin position="151"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH58590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="191" mass="20900" checksum="79E8B68B5D1CDA1F" modified="2009-05-26" version="1">MDTNRLAKELKEIQADTTSGVTVRVLGDNMAHMQGTILGPEESPYQGGKFVVDIQLTNAYPFEPPKMRFITKVWHPNVSSANGAICLDILKEQWSPALSIKTAMLSLQALLSSPEPSDPQDAVVARQYLDDIALFNATAKAWTEEHAKDGAKDEKMEKFKEMGFPEVDIVNALARAAGDEAQALELLLTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN22</accession>
    <name>C1MN22_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_7818</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057505.1">
        <property type="nucleotide sequence ID" value="XM_003057459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN22"/>
    <dbReference type="STRING" id="564608.C1MN22"/>
    <dbReference type="GeneID" id="9682944"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_7818"/>
    <dbReference type="eggNOG" id="KOG0589">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WMEIHAN"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH59150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="178" mass="19319" checksum="35BCC31F77CCCF0B" modified="2009-05-26" version="1" fragment="single">MSHCEGGDLASLMRSVNARGEALPEEVVMRWVVQLLLALQHVHALGIIHRDVKPANVFLSRNLKVVKLGDFGVAKRLSHVNDLANTVVGTPLYMSPELCAGKPYTYAADVWALGCVVLELALGGKKAFESRGYGELLVKISRNDYAPVPSRYSRPFAALVGSMLAPDPRERPAAEALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MN29</accession>
    <name>C1MN29_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_32645</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057509.1">
        <property type="nucleotide sequence ID" value="XM_003057463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MN29"/>
    <dbReference type="STRING" id="564608.C1MN29"/>
    <dbReference type="GeneID" id="9682470"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32645"/>
    <dbReference type="eggNOG" id="ENOG502QW3V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SDTPYCC"/>
    <dbReference type="OrthoDB" id="998115at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31152">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31152:SF1">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="311" mass="33527" checksum="8FDCA74D1FD3F5F5" modified="2009-05-26" version="1">MGRHQPPPGVGAVAMPGSKKDKQEGRKAYTNTWAAGDIHKACCANPGFCCVALFCPCCVAYSQRKTLMFGDLTNYTCCNGDMCISGKVGEKNCPEFCLCCEVTCCFASAVATSRFMIQDEMRVENTKCDNCIIGFMICLQQLACIFRIAACITQNEQIERCADILDCVADSVYCSVCACMQTQQHEQIKLRDPAARAPGEIQGAMQPPPPPQQQQQPPPQPGYGQPAYGQPAYGQPVQPGYGQPAPAYGQPAYGQPVQPQYQQPPPRRPRGEPSGAPPAPSSPSSSSSRSPRPSRARPTRARPSAPRSRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNF6</accession>
    <name>C1MNF6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_61934</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057096.1">
        <property type="nucleotide sequence ID" value="XM_003057050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNF6"/>
    <dbReference type="GeneID" id="9682100"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_61934"/>
    <dbReference type="OMA" id="NARCREV"/>
    <dbReference type="OrthoDB" id="2124888at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="380" mass="43450" checksum="D1DB4369CD521B97" modified="2009-05-26" version="1">MHSRAWDYVHLDPFGSVAPHLGASHTLVPIRPRSRGERRFLRTFAGASLRPPLAFNPRPRRLSTPSDAFQLHPDVRSYGTTLRRRRRESAARGDRERVRDGRVVPLRRVPGRRQAAIRRGSGSSRRTERRRFKQLRLSWPPPRVVQRARRSRSDRRRRARGGAARARDRGSPLVRPEGGALRVGRRSRASRRRRRGRGGGADRDDVALRRVRGVRSRRRRRRRRRERARVDVRVRTRGRGRGRTNRIRNRAETDEARTGVVGRARVGGVRVEDAGARRRGRRRVSRGARDDVALAATREGSVGRRGRRVVSLRGRVRRPSHGGAPERGRARGRAAARGSRRVEDALRRARGEDGRERGGVEVRSIHWSPYDRVGVVDADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNR9</accession>
    <name>C1MNR9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_8217</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056694.1">
        <property type="nucleotide sequence ID" value="XM_003056648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNR9"/>
    <dbReference type="STRING" id="564608.C1MNR9"/>
    <dbReference type="GeneID" id="9682597"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8217"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="407558at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000025">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase CYP19-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH58339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="154" mass="16646" checksum="673B57C55CCF84E8" modified="2009-05-26" version="1" fragment="single">NPRARLRVEIDGVDVGALVLELFASDAPRTCENFLRLCEGRDRSTRADSNAALDYVGSVFHRIIPGFMAQGGDFERGDGTGGESVFGPTFADESFSRRHDARGALAMANSGRHTNASQFYVTFAPAPRLDGKHVVFGRVTSGFHVLDALERVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP72</accession>
    <name>C1MP72_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46667</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057234.1">
        <property type="nucleotide sequence ID" value="XM_003057188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP72"/>
    <dbReference type="STRING" id="564608.C1MP72"/>
    <dbReference type="GeneID" id="9682210"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46667"/>
    <dbReference type="eggNOG" id="KOG2048">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="STYITEW"/>
    <dbReference type="OrthoDB" id="8883818at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035266">
        <property type="term" value="P:meristem growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010073">
        <property type="term" value="P:meristem maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044622">
        <property type="entry name" value="PCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45086">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN PCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45086:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN PCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="610"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="793"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="871" mass="90673" checksum="C80799F28712E2E0" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1MP80</accession>
    <name>C1MP80_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56177</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056774.1">
        <property type="nucleotide sequence ID" value="XM_003056728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MP80"/>
    <dbReference type="GeneID" id="9682678"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56177"/>
    <dbReference type="OMA" id="IMADEFW"/>
    <dbReference type="OrthoDB" id="10610039at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="192" mass="22070" checksum="F18185BB9FB358C7" modified="2009-05-26" version="1">MNANFPLSRGGAREAGAMQRRAYHEAGGGPRKHRGKARAPNRVAEVRAQATGGASRYDDGDDSDDESDDDGRDDALVAIMADEFWVLLFAIVYAFGFVFFVLGCTFKWYGSRHPFWTRVIWGFAGWVVLTTMYILDPRLEHWKRRLTPSLKAANRAWRWAVDTWREKKIGDAIAEWWRWRTTYKPPPVAEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPA0</accession>
    <name>C1MPA0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_38692</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057248.1">
        <property type="nucleotide sequence ID" value="XM_003057202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPA0"/>
    <dbReference type="STRING" id="564608.C1MPA0"/>
    <dbReference type="GeneID" id="9682224"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38692"/>
    <dbReference type="eggNOG" id="KOG3969">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HVHINPI"/>
    <dbReference type="OrthoDB" id="10264956at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008594">
        <property type="entry name" value="DcpS/DCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12978">
        <property type="entry name" value="HISTIDINE TRIAD HIT PROTEIN MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12978:SF0">
        <property type="entry name" value="M7GPPPX DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="336" mass="37623" checksum="1E72666F30E44F1D" modified="2009-05-26" version="1">MASSLHDAMPDRLPSLRGFKTSRVLNDGKESGVVALLGTFPGCDTESVVKLSRPPIPLGDLDGLATAVTLSERAPYSGMEYGYYHGVVASEFAPGLSVDVLYPGCLANESEEARAKLLAKHVSRNASQAPVVFRENPRAYAAAHLPYIDAIPSSAIGWVYKILNKEKELERLLFDDDDANDGFLVNTDPKWVTHPDPKATPKEQWMNHPGTRELYCLGLCHRKDVRSLRDLRAAHLPMLRAMARKGREVIKNTYGLADESLRIFVHYPPQFYHFHVHFTNVSVDHGVSAERAHLLDDVIENIERDSEHYAKCSITCRMGENDELWRRFKELDKAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPU3</accession>
    <name>C1MPU3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_26188</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PRP38 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057645.1">
        <property type="nucleotide sequence ID" value="XM_003057599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPU3"/>
    <dbReference type="STRING" id="564608.C1MPU3"/>
    <dbReference type="GeneID" id="9683448"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26188"/>
    <dbReference type="eggNOG" id="KOG2888">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IYNEVDH"/>
    <dbReference type="OrthoDB" id="3881at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="238"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="257"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="326"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="361" mass="41392" checksum="98026FBB9D781AB6" modified="2009-05-26" version="1">MSRASIRIHGDATAMALLGGQALDNGKSYNMEKVLRTNILASDYFSQLVKMNDFYELVDEIYNEVDHVEPWMSGNARGPSTAFCLLYRLFTMEIEDNEVKHLINHGDSPYIRALGFLYVRYARDPKEFGRWFDEFLRDEEEFSPSPHGKSVTMGAFVRDLILDQYYFETIFPRIPEVSRRALVERIKKFGFSDKAAGCGGAGGQRRGGGPSSGGARPMSVKAALSVNMGQRAPHVQAAMERGRGVDPTTTVAAGAASKDRDRDRDRDRDRDRGRDRDRERDRDRDRDRRRERDRSRERDRSRDRDPGRYGKLYGKDSGKNGGGGGGRDRSRDRGKPYDRPRDRSRDRYRGDRSRSRSRDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ61</accession>
    <name>C1MQ61_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="22">Flagellar outer arm dynein alpha chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">ODA-DHCA</name>
        <name evidence="22" type="ORF">MICPUCDRAFT_70194</name>
    </gene>
    <organism evidence="23">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057702.1">
        <property type="nucleotide sequence ID" value="XM_003057656.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1MQ61"/>
    <dbReference type="GeneID" id="9683509"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70194"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WAYLVND"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000007">
        <property type="entry name" value="Dynein axonemal heavy chain 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000001">
        <property type="entry name" value="dynein heavy chain 17, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000009">
        <property type="entry name" value="Dynein heavy chain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000738">
        <property type="entry name" value="Dynein heavy chain axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001275">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000049">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000007">
        <property type="entry name" value="Putative dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017868">
        <property type="entry name" value="Filamin/ABP280_repeat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001298">
        <property type="entry name" value="Filamin/ABP280_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF8">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00630">
        <property type="entry name" value="Filamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00557">
        <property type="entry name" value="IG_FLMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00429">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50194">
        <property type="entry name" value="FILAMIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="12 18" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0243">Dynein</keyword>
    <keyword evidence="10 22" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="14" id="KW-0505">Motor protein</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="IPT/TIG" evidence="21">
        <location>
            <begin position="288"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="17">
        <location>
            <begin position="378"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="1673"/>
            <end position="1842"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="2332"/>
            <end position="2477"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="2679"/>
            <end position="2838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="592"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="3621"/>
            <end position="3640"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="1370"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="3145"/>
            <end position="3207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="627"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="678"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EEH57653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="4441" mass="496849" checksum="D0202DE1C8ABD22C" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQN2</accession>
    <name>C1MQN2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug/Metabolite transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_57352</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057789.1">
        <property type="nucleotide sequence ID" value="XM_003057743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQN2"/>
    <dbReference type="GeneID" id="9683593"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57352"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CATEETF"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="15"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="337" mass="36290" checksum="09760EAA0D9B8231" modified="2009-05-26" version="1">MPPVVKSALAYYVRAVAYVSLWAAASVTLVMANSYAIRVDEFEFPMTISMCGPLLTFLVALVAVLSGHTKLTRRMTAGEYARTMLPVGVCTAFSLAIGNALYLYFEVSSVQLLKAFSPVVTGGMLVALGMDVVTAPKLCGVVMMTGGTALACSGMTEFSVVGFCIVLGGELVEGSRMVLWQHVLKTKKMPMIEGLLYYAPAAFVFLATGVAIFERDAFSESENSRKLSRKPHLYLGIGVLGALVSVGTVGAIQICGSLTFKALAQVRNAVIIFGAVLFYGDDLTIREVCGYVVTLSGFTLYQYYRTQEDMREIRATGYDAIGEGEKEGLLAKQKRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQQ2</accession>
    <name>C1MQQ2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57371</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057799.1">
        <property type="nucleotide sequence ID" value="XM_003057753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQQ2"/>
    <dbReference type="STRING" id="564608.C1MQQ2"/>
    <dbReference type="GeneID" id="9683603"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57371"/>
    <dbReference type="OMA" id="ERICKYI"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="471" mass="50117" checksum="4D4533A358C8EC64" modified="2009-05-26" version="1">MVKTAGPATPATETEAAPADATETPVAAETEAPAEAEAVAEEEAPAAEEPAAPEEAEAADAEAPASDEAPAVEATEEDAVEPAPAEEEEAVEPADADADADANPPRPDSVADSAKAESVAGSVASSAQLYGKDMGATPSYSNFFADGTPRDTPMGSSADLVADLAAAAEPTPETAAAPEPTPEPTPEPAPEPTEPEKPKPAAAAAARGARPPSKAFVPNRPPRPAPVAVPDTPEASPASPNRASVPRTPKHTKQDVRDAVDVVYAYAKKDPCDALAEMAELMCVKHRSEYPNVHVLFRRTLQKMKEDAEAEAKRKAHPPSSSSADEDKRTRRGRDSATSLASTARSSDGGVKSPIKKKTRLGSTLPPSGGRQRPSDTMRSAPDEMHRSAKLSVKEICKPNQSTRKWMQEKQMKENERARMKEQMHAKELKWMEEITMKQNIRNKANAKLKAQEEERAKMASREAREKLASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRV1</accession>
    <name>C1MRV1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58241</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058936.1">
        <property type="nucleotide sequence ID" value="XM_003058890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRV1"/>
    <dbReference type="GeneID" id="9684014"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58241"/>
    <dbReference type="OrthoDB" id="10484170at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="176" mass="19711" checksum="7F350D2C18E77F0D" modified="2009-05-26" version="1">MTDAIARAHDIAAIASNSSSHDVVRWHSPFGPELQYLAAHPTQTAIVAAMLACVGVFVHVARERVNALKAEFLSDGVDLTRVEDRIDTLQYLKKMHERGMLPLGLEVCAMKQAENEVLFLGPVGVEKWRAYYRERGIDIDGAEDMKRVQKYVRDLHYLEGCLLEVDVESLMLSDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS21</accession>
    <name>C1MS21_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Squalene monooxygenase</fullName>
            <ecNumber evidence="5 12">1.14.14.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUCDRAFT_49604</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>squalene + reduced [NADPH--hemoprotein reductase] + O2 = (S)-2,3-epoxysqualene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25282"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:15441"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the squalene monooxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.17" evidence="5 12"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058610.1">
        <property type="nucleotide sequence ID" value="XM_003058564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS21"/>
    <dbReference type="STRING" id="564608.C1MS21"/>
    <dbReference type="GeneID" id="9684410"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49604"/>
    <dbReference type="eggNOG" id="KOG1298">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AKRTFYW"/>
    <dbReference type="OrthoDB" id="1678617at2759"/>
    <dbReference type="UniPathway" id="UPA00767">
        <property type="reaction ID" value="UER00752"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004506">
        <property type="term" value="F:squalene monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013698">
        <property type="entry name" value="Squalene_epoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040125">
        <property type="entry name" value="Squalene_monox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835:SF0">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08491">
        <property type="entry name" value="SE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="13">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Squalene epoxidase" evidence="14">
        <location>
            <begin position="178"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEH57065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="493" mass="52689" checksum="34F13504D84EABF3" modified="2009-05-26" version="1">MGRGGEATVSGGSGFEWDVIVVGAGVAGASLAYTLGNEGRRVLLLERDLSEPVRIVGELLQPGGYLKLKELGLAHCVDKIDAQKVYGYAMYKDDGEALVGYPLEGRGDDVAGRSFHNGRFVMRLREAARGCDRVDLRQATVKKLLAQDGAEWTAESGGVIGGVRAAVKDGGEERSFMAPLTVVCDGYFSSFRKKLTPAASPVSPSTFVGIIMEGKPDDLLPRPGHGHVILGDPSPVLFYPISSKEVRCLVDIPAHVKMPSVASGAMAAYVLEKIVPQVPEKLRAPLTKAVNEGSFKSMMNKTMPAQPSRTPGAVLLGDAFNMRHPLTGGGMTVAFSDVVTMKSMLAPLPSFEDDAAVGERVDAFYAHRTRPALTINTLANALYKVFCSSGDASMEEMRRACFEYLRLGGSMSSGPIALLGGLETNPLKLVAHFFSVALFGVGRLMVPLPTPGRIWKGCNLLAGAVKIIAPIAWGEGIVRMFVPSGMRERWGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS87</accession>
    <name>C1MS87_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58390</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059006.1">
        <property type="nucleotide sequence ID" value="XM_003058960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS87"/>
    <dbReference type="GeneID" id="9684080"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58390"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="130" mass="13739" checksum="6FAB37DC8FE55269" modified="2009-05-26" version="1">MVSHRAAPSPENIVVAVFVGLSLGIAASFVFLCACVLGARAYHHQIQISEARASVANASRIEARANRDRKDDDDDVDDVDVVLRTMRGVVVEHPGGETDFATSRSPVADVVERPIVVARSRRGASGGSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSC7</accession>
    <name>C1MSC7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_17015</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059029.1">
        <property type="nucleotide sequence ID" value="XM_003058983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSC7"/>
    <dbReference type="STRING" id="564608.C1MSC7"/>
    <dbReference type="GeneID" id="9684097"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17015"/>
    <dbReference type="eggNOG" id="ENOG502QTEG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ETCTDYT"/>
    <dbReference type="OrthoDB" id="286233at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044243">
        <property type="entry name" value="FLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47310">
        <property type="entry name" value="PROTEIN FLUORESCENT IN BLUE LIGHT, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47310:SF2">
        <property type="entry name" value="PROTEIN FLUORESCENT IN BLUE LIGHT, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="185" mass="19781" checksum="DDC3864775A69AD2" modified="2009-05-26" version="1" fragment="single">VALVGAIGAGLSSNARKAEIAELNEKLRAVNVALRQQIRNPSPNAAPGATAGALSKDFDSASLDELKKALREGRALLKVETPAAYAEAEKVFNKALMLSRMQGDQVQIRRATRGLAASKRGLGDTKGSIVFLKEVLDISRQLGDRTGDTDALGNIADLYTEIGDLENAGKYYDEYLDALNDEMST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSH4</accession>
    <name>C1MSH4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_40021</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059053.1">
        <property type="nucleotide sequence ID" value="XM_003059007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSH4"/>
    <dbReference type="STRING" id="564608.C1MSH4"/>
    <dbReference type="GeneID" id="9684120"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40021"/>
    <dbReference type="eggNOG" id="KOG3082">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10268103at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138:SF5">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="FMT C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase C-terminal" evidence="3">
        <location>
            <begin position="68"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH57508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="199" mass="20979" checksum="78837119FFD8D17A" modified="2009-05-26" version="1">MDAGPVLRRIERPLLGDEKHPELLEELFGLGARALVDALPDVWSGAAAFDAGTTPQESYGEASHAAKVSVEESELDFCDGELSARRLHDKVRGFAGWPGTKATFAVRKETEAAADAKEVSLKIVTTRVGGEGEGEGDDAAARAAGTVVIRKDCMRVPCAGGGWLEITELQPPGKKAMSARDYVNGLKGSVVAVKKTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSM1</accession>
    <name>C1MSM1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_47198</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058348.1">
        <property type="nucleotide sequence ID" value="XM_003058302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSM1"/>
    <dbReference type="GeneID" id="9684142"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47198"/>
    <dbReference type="eggNOG" id="KOG1330">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="YPWIVFA"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF79">
        <property type="entry name" value="PROTEIN SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="24"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="472" mass="48248" checksum="38EE1BB49CA88B53" modified="2009-05-26" version="1" fragment="single">MPSPSPSPPPPIPTSATWFTPERLLALFCAMSMLIYLDRGVISSAAVSGAPGTRSAPLGSGLQGEFDIGYAEYGLLQAAFMTGLLIGCPIFSSLSKRRNPFKLIGGGLACWTVATFLCGVAPNYASLFVARAVVGVGEASFCALAAPFIDDYAPPSRKTTWLATFYLCIPLGIAFGFMYGGVVGSALGWRWAFILESVAMAPVVAFCADAAPVPMRGVNGGCRTHSGDGGSDGEEEELGADGSRGGREGAEDRVSLLAAAEAAAAAAEAATLEGGARGDADDGDVDLAVDIDDADAGTGANEMTASATLRRRAARDATRAAAATKTMRLDFLRDASQLAKIPVYVLTVAAYVAYTAVVGVYAVWGPKAGYAIYGSALKTRGDADFALGGITVVAGVVGTLLGGRAVDAFGASRRAAITVCAVSSVAAFALLEASFQAPTFAIFACVFLIGETLAFVVQAPVNAVILWSVPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSQ2</accession>
    <name>C1MSQ2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS15c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_57777</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058717.1">
        <property type="nucleotide sequence ID" value="XM_003058671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSQ2"/>
    <dbReference type="STRING" id="564608.C1MSQ2"/>
    <dbReference type="GeneID" id="9684156"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57777"/>
    <dbReference type="eggNOG" id="KOG0009">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2815">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FTTMASW"/>
    <dbReference type="OrthoDB" id="3446at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_uS15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006846">
        <property type="entry name" value="Ribosomal_eS30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_uS15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47546:SF3">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S15, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47546">
        <property type="entry name" value="S15/NS1, RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04758">
        <property type="entry name" value="Ribosomal_S30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="270" mass="30383" checksum="E3548D44B4166CB5" modified="2009-05-26" version="1">MGKVHGSLARAGKVRGQTPKVAKQDKKKLPKGRAIKRLKYNRRFVNVVVGLGKKRSPNSNAHISSNTTRRVGHGVFDAPRSVFVSAVGRGDADDDEKEGGAAVGEAARVRSVELGGDLEDDADVYAERRSSRDPSEMKPELVRRYVSSEHFNARERAKAERAEIRAGFQLHPHDVGGSEVQIAQLSHKISHLTEHFKARRKDVHSRMGLQRMLERRKKLMRYLRRTNGDSYGDVIFRLGLKDPKTNDPAGGKYAYRDEQIRARLRKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSV4</accession>
    <name>C1MSV4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_17492</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058746.1">
        <property type="nucleotide sequence ID" value="XM_003058700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSV4"/>
    <dbReference type="GeneID" id="9683795"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17492"/>
    <dbReference type="eggNOG" id="ENOG502RXAI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PTDNMEL"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052736">
        <property type="entry name" value="Stf3_sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36451:SF1">
        <property type="entry name" value="OMEGA-HYDROXY-BETA-DIHYDROMENAQUINONE-9 SULFOTRANSFERASE STF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36451">
        <property type="entry name" value="PAPS-DEPENDENT SULFOTRANSFERASE STF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13469">
        <property type="entry name" value="Sulfotransfer_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="350" mass="40210" checksum="D4756DD548FBEC8B" modified="2009-05-26" version="1">MRDHGSHVEIATYFPRLIFLTIMSLVNTIGAIADSVLYGRAIASQELNDEPVFILGHPRTGTTHLHNLLSRDPSFAFATTFSVGFPSGFLSCRWLAPFMGAIMDDTRPMDNMALSHDTPQEDEVATNQLSGGASPYMPLMFPKREALFRRWYSMRDGASSAEIARWKESFLYFLRKTQYAAGGKRKRLLLKSPVHTARVDVLREMFPKAQFVFIHRNPYEVFQSAVHMADAYYWQCYFQVPSAEDVQEFILYQGEYLHDAYERDIRKVKKGNKHEVRFDELNKDPLGTLRALYDALGWSANFASIRPAIESYAGSLRDFKMNAHARLSEEAKEVVRARWGNWFKDLGYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTW6</accession>
    <name>C1MTW6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_11360</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059391.1">
        <property type="nucleotide sequence ID" value="XM_003059345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTW6"/>
    <dbReference type="STRING" id="564608.C1MTW6"/>
    <dbReference type="GeneID" id="9684831"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_11360"/>
    <dbReference type="eggNOG" id="KOG3240">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ASHWTHA"/>
    <dbReference type="OrthoDB" id="10251079at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003881">
        <property type="term" value="F:CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362:SF4">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="188" mass="20788" checksum="D71D439FA70E466C" modified="2009-05-26" version="1" fragment="single">RNVFLYVPNLIGYARVALTIASLLTAFSRVEFSLAAYFLSFVCDELDGRFARMFDQCSEYGATLDMVTDRLSTTGLLMVVAAEVPTLFYPCVGLVMLDIASHWVHVHASSLRPGGKKSHKDVADSRYFLLRLYYSNRAFMGVCCVSCEVFLGAFDTVAKQLCVAALPGFAMKQFANWCQLMGSSRALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU86</accession>
    <name>C1MU86_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_58708</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059152.1">
        <property type="nucleotide sequence ID" value="XM_003059106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU86"/>
    <dbReference type="STRING" id="564608.C1MU86"/>
    <dbReference type="GeneID" id="9684893"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58708"/>
    <dbReference type="eggNOG" id="KOG0144">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TERAIHF"/>
    <dbReference type="OrthoDB" id="410044at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="SAP" evidence="6">
        <location>
            <begin position="11"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="497"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="48"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="455"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="670"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="670"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="686"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH56284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="704" mass="72195" checksum="EB593D3BB2CBA84E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUG5</accession>
    <name>C1MUG5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58798</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059490.1">
        <property type="nucleotide sequence ID" value="XM_003059444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUG5"/>
    <dbReference type="GeneID" id="9684634"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58798"/>
    <dbReference type="eggNOG" id="ENOG502S8PR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FHTIRAH"/>
    <dbReference type="OrthoDB" id="10260017at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="352" mass="37737" checksum="F216A6482CCDF901" modified="2009-05-26" version="1">MGRGADAAGGDPVAAAVAAEKAAAEAATSPPSPPSSSSRDWHFLPYPVGHRKRASFVRHYETLLAARADAAARHAYVPSVRAALDGDGFASLRRLNVLTFDPAAHPVLRAFRALIGVADDADLSRAHLSFRDFSRRSSHLDDKASLLAPLARDSPARDAFVDAYDALVLAVVAPAVAAAMGPELEDAILYAAFPCVRVQQPCEFHTIRAHVDSMYNHPEGSVNCWLPLTSAFGANTLQLESAPGAEDFRPLELDHGAVAMFHGHSVAHFTVANTTDETRVSLDFRVVPRSVHDPSAECTARKGPGDASARQCYNVSGYYSAARRGDDGIWRKVVSGRPSARHGFPHRNDEMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVE3</accession>
    <name>C1MVE3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="2">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_59342</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059736.1">
        <property type="nucleotide sequence ID" value="XM_003059690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVE3"/>
    <dbReference type="STRING" id="564608.C1MVE3"/>
    <dbReference type="GeneID" id="9685462"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59342"/>
    <dbReference type="eggNOG" id="ENOG502QQ0A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="37244at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:proton-translocating NAD(P)+ transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160">
        <property type="entry name" value="NAD(P) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160:SF19">
        <property type="entry name" value="PROTON-TRANSLOCATING NAD(P)(+) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="NADP transhydrogenase beta-like" evidence="10">
        <location>
            <begin position="33"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH55688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="233" mass="25340" checksum="ACFC9976BF45F288" modified="2009-05-26" version="1">MSNIQRQKYSISAQQQDDWCIFCKCFVQKNATVAGAILSQIMCVAMNRSIVGVLLGIKGTLNKTKTVDVDPNMLCDVERGECVVSDAGTAAQDLADAKKVLIVPGYGLAVSKAQYAMADLIELLRESGKDVVVAVHPVAGRMPGQLNVLLAEAGVPYDVVKEMEEVENDVDKYDVSLVVGANDTVNPSAVEDPNSELAGMPVIQVWRGSTPFPVSSFVFVTYHGLRVRFRRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVI5</accession>
    <name>C1MVI5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_59391</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060044.1">
        <property type="nucleotide sequence ID" value="XM_003059998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVI5"/>
    <dbReference type="STRING" id="564608.C1MVI5"/>
    <dbReference type="GeneID" id="9685482"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59391"/>
    <dbReference type="eggNOG" id="KOG4166">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10006023at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF86">
        <property type="entry name" value="ACETOLACTATE SYNTHASE LARGE SUBUNIT ILVX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="THIAMINE PYROPHOSPHATE ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="3">
        <location>
            <begin position="24"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="272"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="326" mass="34482" checksum="6BCDCA5973321978" modified="2009-05-26" version="1">MPRFAPSAAKQPVEKRVERPKAPTGAESMMKALADRGVEACFANPGTTEMWLVGALDAEPRVRPVLGLHETVCAGAVDGYARMARKPACTILHLGPGLANALANLHNARRANVPVLNIVGDMSTWHRGADALLEMDVEARSISHWPFAGASLRPPLDFNPRPRCLTTPTDAFELHPDVASYGLALNVEALAAAVSSHVHTSTVPGAMRSDAIDALKATDRSETNADGRGRVATLIVPHDRTWERTGSLLASIMDSDDEDDVDDAKRAAPASYVPPTPAPHPAPSSVINAGDDATAFVTAAVHDAVRGALALRCVLYTGPHTTPSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MW26</accession>
    <name>C1MW26_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_47749</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059851.1">
        <property type="nucleotide sequence ID" value="XM_003059805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MW26"/>
    <dbReference type="GeneID" id="9685580"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47749"/>
    <dbReference type="eggNOG" id="ENOG502RA6R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2020089at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005134">
        <property type="entry name" value="UPF0114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31721">
        <property type="entry name" value="OS06G0710300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31721:SF4">
        <property type="entry name" value="OS06G0710300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03350">
        <property type="entry name" value="UPF0114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="216" mass="23155" checksum="8DA321F5E6F6407F" modified="2009-05-26" version="1">MDEGSVDESNDSGDDDPRDDDAPRRAAVRKTYSSFEYAFVRLTLFLTGGFVLTGVVASLTLSALLFTMGMREVAGDAVTAWATNNPVELVTAAVGALDRFLLGMVCLVFGLGSYELFLARSNREGEIRDKRLKKLSWLRVTSIDDLEQKVGEIIVAVMVVNLLEMSLHMKYAVPLDLVWAALAALASAGALALLHWSSGHDKHKGPGGEGSGAGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWC7</accession>
    <name>C1MWC7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_71063</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059902.1">
        <property type="nucleotide sequence ID" value="XM_003059856.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWC7"/>
    <dbReference type="GeneID" id="9685630"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_71063"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="584"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="641" mass="64398" checksum="D672E089C9108285" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWM9</accession>
    <name>C1MWM9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_47624</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059953.1">
        <property type="nucleotide sequence ID" value="XM_003059907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWM9"/>
    <dbReference type="GeneID" id="9685392"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47624"/>
    <dbReference type="eggNOG" id="KOG2132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DIREPPY"/>
    <dbReference type="OrthoDB" id="47172at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF105">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="196"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="346" mass="37432" checksum="1DA766E5CD7B2A7C" modified="2009-05-26" version="1">MDSPRDERKARIAVERATALAELATTHGCESGAIGDVRWVGDAYVAASDAFDAATTTSDLTSPTGSGRPPPPLARLPTAGVPTGVPTPSGRPGANGVPTYDASSFRAPAFVNAHLSPRRSPCVIRGLMRHQKWSAAETFPDLEWLRSHHGDALVPVEIGVASADGKRAVPRIELTRLATFLNDHFADATTPRDDVAYVSQHSLLHQRPELQRHFAVPEYCVGRLAAANAWIGTAGTITHLHTDAADNILTQVAGIKSVRLYSPDVGEAHLYPERRGGNGAVNAFSPIDPDDANSPELLSRYPKFGEIPEEEIMDVELGPDDSLFIPKGWWHRVVARTPSFSLNFWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWS6</accession>
    <name>C1MWS6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_71054</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059976.1">
        <property type="nucleotide sequence ID" value="XM_003059930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWS6"/>
    <dbReference type="GeneID" id="9685113"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_71054"/>
    <dbReference type="eggNOG" id="ENOG502SCXR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QNKNCAR"/>
    <dbReference type="OrthoDB" id="2019425at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="193" mass="19756" checksum="1EBA736101D21E37" modified="2009-05-26" version="1">MSVAPPCSAPSRALARPRAPSRGRAAVVVAAASPPERRAPDDPRASRLGRRHHLASSVALASLLASPLAARAVEPPTTPDASSSPYIRSLLAKSEANRELRELELQNKNCLRQSDMGIGDCAGLSRDDLKAAMDESVRRLEKRKTAEAAEAAEEERLLAAGAAAEARSAEAAAASENESGGGGGGGGGGGETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXF3</accession>
    <name>C1MXF3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_69078</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060385.1">
        <property type="nucleotide sequence ID" value="XM_003060339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXF3"/>
    <dbReference type="GeneID" id="9685823"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69078"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028941">
        <property type="entry name" value="WHIM2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15613">
        <property type="entry name" value="WSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WHIM2" evidence="4">
        <location>
            <begin position="71"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="117"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="197"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="424"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="491" mass="50632" checksum="16F1655C7683FC78" modified="2009-05-26" version="1">MDGAKVGGDKDGKGIGGGPGSGPAMKSYAVRMAGIAAANDANPVIPEAEGRARWQAKWHELEGNLRANDLRLDHLGVDRDDAAYWLIGNWGLVGRQPSGAGGGEGFSIGGLGGVATSSAAKKKKRKSTDGVDDSFDDGGDVDVTMEDDDDVADANADAKTPGPSSGGGGGGEYADKPPDESMWGVYGDAEKVATLAASLNEKGEREGSLWSELQRRFGAPRVEGPKPPSVESGDEDAANPGEGDATATATPPADGDLGRTADEGHPGATKKKTKPLAPPLPPIDAVVAVPPPPPDDGAWKPPRPVGAENSEPTGPGAAIAAARTELLAIDAALPDDAMCPARGSQTRRASWRRMTTSATDPATLAMSSVLLEASLAKNWLSPAWLPWSNPAPALRAASRANVSVAAAGVLMRAHALRRAVVWGGGAKVEKPPPPPPPPRETREERAARRAREAIGEWERPPEGMDADAAAALAVAAAADAEESERKRRRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXH2</accession>
    <name>C1MXH2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_60158</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060693.1">
        <property type="nucleotide sequence ID" value="XM_003060647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXH2"/>
    <dbReference type="STRING" id="564608.C1MXH2"/>
    <dbReference type="GeneID" id="9685833"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60158"/>
    <dbReference type="eggNOG" id="KOG0374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SHWMRGL"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546:SF4">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="85"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH55462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="402" mass="42171" checksum="ADC5758E742D783E" modified="2009-05-26" version="1">MLCAARTWVRATMRTAPRLSSRVPGGNATSSLTRGGDRASAHVASLRRRVAPMCASSAAPGASSTSPPAAGAGPYPPLRVTAKGRVVALGDVHGDIGQARRALTIAGVLGEDGDAVNPTWIGGDTVVVQVGDVLDRGDDEIAILILLQKLHKAAQADGGAVYILNGNHEVLNVSGDFRYVTQGAFQESTRFGEHLVNLFGDAFRDAFGGNEEDPRKKQVKARVGLFSPGGPLAQQLAMNSTVLIVNDTVFAHGGLMPRHVEFGLEKLNNAVADWMRGAEISSEEDRTALGMAIGSVKDSVVWNRTFGQENFMSQGDRDRACETLGKTLDAIDGAKRLVVGHTPQLGGCNAECDGRIWRIDVGMSFGVVGADPEVIEIVGDEVRVLTSRVPAGAGSAGAVSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXI4</accession>
    <name>C1MXI4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_27983</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060698.1">
        <property type="nucleotide sequence ID" value="XM_003060652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXI4"/>
    <dbReference type="STRING" id="564608.C1MXI4"/>
    <dbReference type="GeneID" id="9685840"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_27983"/>
    <dbReference type="eggNOG" id="KOG4300">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FEYFICK"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF96">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01184">
        <property type="entry name" value="UBIE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="14"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="173" mass="18379" checksum="6AB29C1D4DFC4C72" modified="2009-05-26" version="1" fragment="single">MRASILSRASGDVLELGVGTGLNLPRYDAANITTLTAVDISDGMLELAVERAMTNLGDAFRALPFDDASFDCVVDTFSLCVFEDPSRAMREVRRVLRPDGVALLVEHSRAPGALGWYQDLTAAPVKSLAKGCAWNQDVRKICEDAGLIVTSSAPSLFGTLLTVEATPGPPPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXV1</accession>
    <name>C1MXV1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_60299</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060457.1">
        <property type="nucleotide sequence ID" value="XM_003060411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXV1"/>
    <dbReference type="STRING" id="564608.C1MXV1"/>
    <dbReference type="GeneID" id="9685895"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60299"/>
    <dbReference type="eggNOG" id="KOG4210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IRMDWQA"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF11">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="97"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="204"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="287" mass="31417" checksum="FE040B79E7360DC0" modified="2009-05-26" version="1">MGEKKEKKEKKEKKEKKEKKEKKRDRDDDDAIAAAAAEKRSKFDDDANDGDDDDDAGIVFKSAKDGGKSASTKPPGGGGERYGAAPPAPGTFPLASTKVYMGNLAWTIDEDALKEAFKDCGDVLSVNWFEEKETKKFLGAGVVEFDSADAAKRAVAAAGRLVHDRETKIRHWEQRGNTGEEKKAAKAAAGRDVKPMGPKPPGCYTLFMGNLNFAIDDDAMFKFFKEGAGVEIAALRWLTNKETGEFRGVGFADFNSDEDIDKAAKLHGTPCMGRPIRMDWQAPKSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MXX5</accession>
    <name>C1MXX5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_60323</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060774.1">
        <property type="nucleotide sequence ID" value="XM_003060728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MXX5"/>
    <dbReference type="GeneID" id="9685905"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60323"/>
    <dbReference type="eggNOG" id="ENOG502S2M6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FAFREMG"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH55543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="484" mass="51055" checksum="15A2257E86B856B2" modified="2009-05-26" version="1">MASSAPTPTPTLDDLWASDRARVSVVVAATPKPGVDFATARDALLAVRWDERSLEWHSTRRGPRDSAAAAAPDDDDAFVVEAVGSCLASGGDESSVAPRVAALAAARFDDAELVVSAPCHVPFLEVRDGVDDPRVRVAAAALLEKEESQGDDARARAVAAFAELGLAASRRRCVASEDLARLTRAATRRMAAAERAMATRHGSVRFGEDAFAFREMGSRGGQRFDLLFPREGEEEEEGGGEGAGEGGGESPQGTAFTTRTGSYGNQSGLERDERDGGDGGEGDAAFVRAFARRAPWVRALVDPILSPPPLSSSSSSSANSASPRRTWWCDVSIVYSKPGARAQDWHCDGRHLAGAARANHAGVGASPPYAICVFVPLVDLNGEVGFTQFWAGSHKADALIGFGSAAEVLRGGVDGKGASYFHTVDAGGFAAYDYRLMHRGMGNFSESTTRPVLQFLYAKSTYKETKNYGSASLFEGGTEGPATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MY54</accession>
    <name>C1MY54_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CorA metal ion transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_41108</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060509.1">
        <property type="nucleotide sequence ID" value="XM_003060463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MY54"/>
    <dbReference type="GeneID" id="9685947"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41108"/>
    <dbReference type="eggNOG" id="KOG2662">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF31">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH55278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="267" mass="28521" checksum="F63047E4A117BDF3" modified="2009-05-26" version="1">MTDMCLTRKEALEAEEAARHGTHAPPSRSPRPRSDGDGDGDGDGDGDGDGTDEKNLSMTWTTNASFDQRDCDADGASASIGGGGGGGDEPRSDATPASASAPRRRRERRRGRDRSSRSPSSSSSASSLSSSSSSSSSSKSSTRSSDPDDEAHEGVEALLEAYYMHVDYSHKRLCELRDAIEDTEDLAEISLDSQRNQLIRIDLLLSNGMLAVGMFSMVAGVFGMNLRTGWESDQQAFRDVCFVSGAASVLVFASVVMYLRAKKLLSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYI3</accession>
    <name>C1MYI3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MutS 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MSH5</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_70184</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060571.1">
        <property type="nucleotide sequence ID" value="XM_003060525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYI3"/>
    <dbReference type="STRING" id="564608.C1MYI3"/>
    <dbReference type="GeneID" id="9685729"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70184"/>
    <dbReference type="eggNOG" id="KOG0221">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CMESEDD"/>
    <dbReference type="OrthoDB" id="547493at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051026">
        <property type="term" value="P:chiasma assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="6">
        <location>
            <begin position="649"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="135"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH55340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="830" mass="89160" checksum="446F40CF6BDF88EA" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYU1</accession>
    <name>C1MYU1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL4c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">50S ribosomal protein L4, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_48008</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061099.1">
        <property type="nucleotide sequence ID" value="XM_003061053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYU1"/>
    <dbReference type="STRING" id="564608.C1MYU1"/>
    <dbReference type="GeneID" id="9686538"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_48008"/>
    <dbReference type="eggNOG" id="KOG1624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SMFFMTE"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_uL4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF17">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="85"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="254" mass="26578" checksum="DF26236A24B222F8" modified="2009-05-26" version="1">MSSVSLSLSARSAVAGAKVPVRRARAAAAKATGPVDVLAAAVEKVSFDGATKSTADLTLKTARADVAKGLVHKYVVMVRQNARRGTASTLTKSEVRGGGRKPFNQKGTGNARAGSIRSPLKPGGGVSFGPKPKDWSIKMNKKERRLAMATAIQSAAGSMIVVDDLGANVSVAKTKTMANALKAWGVEEGEKAYVITKDASDAVKLSTRNMAKVVQSDISHLNVYDVLNADKVVVEESALKYINDFYGAEGGAWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MYW2</accession>
    <name>C1MYW2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_41166</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061109.1">
        <property type="nucleotide sequence ID" value="XM_003061063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MYW2"/>
    <dbReference type="STRING" id="564608.C1MYW2"/>
    <dbReference type="GeneID" id="9686292"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_41166"/>
    <dbReference type="eggNOG" id="KOG0406">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CERCLEI"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="128"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH54759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="367" mass="38955" checksum="199BFDA3C720ED8E" modified="2009-05-26" version="1">MALALASWTTRAAIHIRAARGARRGGARTPHRARTRTTTRADGAAHVGIVSEDLVDGSSLVATRLAPERGGASSASSSSTASSAAASILSADDVDGSSLVATRLAPQSQSRSRPPRDPSRPLLYVSPTCPFAQRAWIALLEKDVEHDIVFEDLANKSEDMKAAYALAGGAGDAKGKTMIESAPVANYVAAAFDGGHELLPTTASEEYDGTMFVDAFGGVGPAFFKSLRATNEKEVEDGLRAVRDALKKAEASRRSTRNVSSPSTALALRSKENADGPFALGSRYSVYDVVASTIAPRVSIVLRHYRGFSLGAELEAMGLTKVKAWAEACAERPSMRRTLEELERVTGKDVATAFVDHFDKFVSWKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZ60</accession>
    <name>C1MZ60_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_34898</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060901.1">
        <property type="nucleotide sequence ID" value="XM_003060855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZ60"/>
    <dbReference type="STRING" id="564608.C1MZ60"/>
    <dbReference type="GeneID" id="9686340"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_34898"/>
    <dbReference type="eggNOG" id="KOG0585">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FCKELME"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF77">
        <property type="entry name" value="SERINE THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="163"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="106"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH54551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="458" mass="50145" checksum="78154DDB3210581E" modified="2009-05-26" version="1" fragment="single">MGPCLSSSRGAHGDSDESSSRKSQDPHDTAIRSDDGVRKRPSSDAAMMMAAQQTHQPELSKPQKDVGDARSRELTEANVAAVSEGNVSGTTARSHQNATTTTKAGLARDLERSSNADRSEDAASDVSETSSSSRRDMPTITTDKVTRYSVRVGEMEYSQFNQYIIVKDLGVGVHAKVALGLHIQENLLYAIKVSHRNAAVAETAVRKEIAILKKLNHKNVLKLYEVIDDQKTNELLLVLEYASSGPIFTRYDKRPLREPLIHRYIRDVLQGLDYLHHAAGIAHMDLKPENLLLMADGSVKIADFGVSFIGQSKAVNSNKKIVGTPAFIAPEMLGEDGYDPYIADIWSLGVCIFHMATAELPFIGRTIFQIVAMAQRQGLRFPPEAVVLSPELKNLLTVILVVDPTKRATLSRIMTHPWVTARGEQPLPPSLADQPLQIDVTEEEIAAAVRADPLATLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZH3</accession>
    <name>C1MZH3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_63395</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061219.1">
        <property type="nucleotide sequence ID" value="XM_003061173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZH3"/>
    <dbReference type="STRING" id="564608.C1MZH3"/>
    <dbReference type="GeneID" id="9686393"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63395"/>
    <dbReference type="eggNOG" id="KOG0537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="EDLWVVV"/>
    <dbReference type="OrthoDB" id="10254877at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000009">
        <property type="entry name" value="Cytochrome b2, mitochondrial, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF1">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="9">
        <location>
            <begin position="568"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="543"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH54869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="645" mass="67365" checksum="8B58063651832CD1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZR7</accession>
    <name>C1MZR7_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_35032</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061001.1">
        <property type="nucleotide sequence ID" value="XM_003060955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZR7"/>
    <dbReference type="STRING" id="564608.C1MZR7"/>
    <dbReference type="GeneID" id="9686440"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35032"/>
    <dbReference type="eggNOG" id="KOG0939">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MQMGRHQ"/>
    <dbReference type="OrthoDB" id="497007at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000079">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000010">
        <property type="entry name" value="E3 ubiquitin-protein ligase UPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF67">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HUWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="11"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH54651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="348" mass="39366" checksum="B276B947E58BF53C" modified="2009-05-26" version="1">MDSFTQLQHLKPAEMRGRLTIQFSGEEGIDAGGLTREWYILLAREMFNPGNALFELSPSGDQSYQPFSNSSVNDHHLAYFKFIGRIVGKAVYDGHLMDAHFTRPFYKHMLGIPLNYEDMEAFDPDYHRNLAYMLEHPLAESGLDHLTMTATTMWFDVEETVDLVPDGANVPVTDENKLEYVNLVTAHKMTNAIKDQIGAFTEGFNDIVPHDVLAILNPSELELLISGTPEIDIEDLRAQTEYTGYTPASPQVRWFWDVVRDLNDEDRARLLMFCTGTSKVPLDGFKALQGISGPQRFQIHRAYGGGQRLCSAHTCFNQLDLPEYANKEELQERLLFAIREGSEGFGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZR8</accession>
    <name>C1MZR8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">T-complex protein 1 subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_35033</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061266.1">
        <property type="nucleotide sequence ID" value="XM_003061220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZR8"/>
    <dbReference type="STRING" id="564608.C1MZR8"/>
    <dbReference type="GeneID" id="9686441"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_35033"/>
    <dbReference type="eggNOG" id="KOG0364">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CGGSTIR"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03337">
        <property type="entry name" value="TCP1_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000073">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000085">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000005">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012719">
        <property type="entry name" value="Chap_CCT_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02344">
        <property type="entry name" value="chap_CCT_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="538"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH54916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="567" mass="61737" checksum="03DE71604BB77E7F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MZY4</accession>
    <name>C1MZY4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription initiation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_60901</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663743">
        <property type="protein sequence ID" value="EEH54950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061300.1">
        <property type="nucleotide sequence ID" value="XM_003061254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MZY4"/>
    <dbReference type="STRING" id="564608.C1MZY4"/>
    <dbReference type="GeneID" id="9686473"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_60901"/>
    <dbReference type="eggNOG" id="KOG1597">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RWQNRNS"/>
    <dbReference type="OrthoDB" id="25790at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20551">
        <property type="entry name" value="CYCLIN_TFIIB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.170:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF78">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="Zn_Ribbon_TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="5">
        <location>
            <begin position="15"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH54950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="370" mass="39520" checksum="A8CD303B9F44AFC8" modified="2009-05-26" version="1">MATAPAPAQQEITKFSQICKNCNVPTAIIEDHQQGDLVCTECGLVLEQGVIDETSEWRTFSDSDKGGADPSRTAGPTNRMLAHGGLGTSIGRNPDGTYNQTLTRLHNRGANPDKALIAAFGKINELADHLGVTSVVKDGACDVYRMVVKPGVSIAGKSQNAMFAACLYISCRQEGTNRTFKEICGGAVNTTVKEIGKCYKFIVKTIDGLNTTMMEQMITPEKLTNRFCGNLGLANLEFLKLATTVIGTFNNLRLSEGHKSEKQPASVAAAAIWLCVQIMDKQHEITLRKISEVSGMAETTITTSYVDMYPYATRMLPRAYVERAARLQAPDLGKDEKAAIAAGLANRDQLELLLGDVPGAGGDGGGGGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N0V6</accession>
    <name>C1N0V6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_9031</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061459.1">
        <property type="nucleotide sequence ID" value="XM_003061413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N0V6"/>
    <dbReference type="STRING" id="564608.C1N0V6"/>
    <dbReference type="GeneID" id="9687143"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9031"/>
    <dbReference type="eggNOG" id="KOG0716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CIYWVKR"/>
    <dbReference type="OrthoDB" id="566614at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45295">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ C76, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45295:SF1">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ C76, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13370">
        <property type="entry name" value="Fer4_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH54089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="63" mass="7114" checksum="626FAEBBA97F6132" modified="2009-05-26" version="1" fragment="single">CIGCKSCVLHAPDTFAMVEDFNAGRARCHTQWGDDEETTQVAIELCPVECIYWVKRSQLPVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1A7</accession>
    <name>C1N1A7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_49693</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061535.1">
        <property type="nucleotide sequence ID" value="XM_003061489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1A7"/>
    <dbReference type="STRING" id="564608.C1N1A7"/>
    <dbReference type="GeneID" id="9686975"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49693"/>
    <dbReference type="eggNOG" id="KOG3411">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WAPFVKT"/>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000118">
        <property type="entry name" value="40S ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001266">
        <property type="entry name" value="Ribosomal_eS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01090">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01413">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH54165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="144" mass="15756" checksum="0924197C1F5F4332" modified="2009-05-26" version="1">MPNAPRTVKDVPAQEFVVALAQYFRSTGKMEVPTWVDIVKTASYKELAPYDPDWFYIRAASMARKLYVSGNMGVGAFRKNYSGAKNDGVCRHHYAIGSGSVARSILKQLEAVGVVEKGPKGRRITPSGQRDLDRIAGRVAVPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1H5</accession>
    <name>C1N1H5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_63099</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061562.1">
        <property type="nucleotide sequence ID" value="XM_003061516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1H5"/>
    <dbReference type="GeneID" id="9687002"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_63099"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="90" mass="10640" checksum="E648C6206FE19E48" modified="2009-05-26" version="1">MRSLVYFIHAPPPPPPPRTATEPSSRLAPSSLQTPRRSSSWRARRGRHLRRDIVVDLRGLRRRLLLLLRVLLPRRVVVRVRVVFRHRENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1H9</accession>
    <name>C1N1H9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51409</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061823.1">
        <property type="nucleotide sequence ID" value="XM_003061777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1H9"/>
    <dbReference type="GeneID" id="9687262"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51409"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH54453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="393" mass="42535" checksum="EB9A54335AB3012D" modified="2009-05-26" version="1">MGSGPNDTMTSKGGAGSGSGGGMNASRRGASGGALNASRGSSSGLPTNRAALLRAAEKKRANEAGYHGRENPAKTSDLPPFWSTSKHGVPYNEGDPMEIAKGGARPGGANAGVFSKSLVRASVSAGLSVSASLGPAQMKLNDLRKALESPHSHMGHEERVRAIAKLPPYEHIVALVKGLGAFYTLVPIRPRWRGERRSLRTLPGASLRPPLGFNPRPRRLSTPLLTPFNSTPTFARMEWPLDRDPYDTTKGPWTGDKPEVWKKDPERCVRRAVVALEARMRESLARVVAAENKKALSPCYTEKDFLMRVFQRVDKNRHGRFTGDCDLAMFLQAWGSAPPEPDDADDDENENEKNEFAGPASVASIASTPKPTEARSISHWSPYDRVRVVHADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1I9</accession>
    <name>C1N1I9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Choline monooxygenase, chloroplastic</fullName>
            <ecNumber evidence="5">1.14.15.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">TIC55-1</name>
        <name evidence="14" type="ORF">MICPUCDRAFT_3322</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the first step of the osmoprotectant glycine betaine synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>choline + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = betaine aldehyde hydrate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:17769"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15870"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.14.15.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (monooxygenase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the choline monooxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.7" evidence="5"/>
    <dbReference type="EMBL" id="GG663744">
        <property type="protein sequence ID" value="EEH54460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061830.1">
        <property type="nucleotide sequence ID" value="XM_003061784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1I9"/>
    <dbReference type="STRING" id="564608.C1N1I9"/>
    <dbReference type="GeneID" id="9687269"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_3322"/>
    <dbReference type="eggNOG" id="ENOG502QQJW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RYNVANY"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="UniPathway" id="UPA00529">
        <property type="reaction ID" value="UER00430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019133">
        <property type="term" value="F:choline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019285">
        <property type="term" value="P:glycine betaine biosynthetic process from choline"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.380.10">
        <property type="entry name" value="Naphthalene 1,2-dioxygenase Alpha Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015879">
        <property type="entry name" value="Ring_hydroxy_dOase_asu_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001663">
        <property type="entry name" value="Rng_hydr_dOase-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756">
        <property type="entry name" value="CHOLINE MONOOXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756:SF5">
        <property type="entry name" value="CHOLINE MONOOXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00848">
        <property type="entry name" value="Ring_hydroxyl_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="14" id="KW-0946">Virion</keyword>
    <feature type="domain" description="Rieske" evidence="13">
        <location>
            <begin position="28"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEH54460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="338" mass="37234" checksum="3AA4F3F14BF2CD7C" modified="2009-05-26" version="1" fragment="single">ASTPPSSWYTDAAIIPAIEARAVFAEGWQAVGRVDQVSDVGDYFTGAVGNFLVVRGDDGDVRAFHNVCRHHAMEATCFRCPYHGWTYDDKGALTKATRLTGIEGFDVSDNGLKPLRVDTWGPFVFVNLGGDDASAPPPVNEWLGEAGERMRSAGVAEMTHVARREYELNCNWKVFCDNYLDGGYHVPFAHPELASGVSMKSYETTIRGLHSLQTVTAAAAAATDRVRDRDDRLGDAALYAFIHPNFMVNRYGKWLDTNWVIPTGAETCKVVFEYYLEKGVEGATEAFIEKSLAASDRIQREDTTLCEKVQEGVRSPGYGVGRYAPAVEAAMYHFHALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N1Z5</accession>
    <name>C1N1Z5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51789</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062000.1">
        <property type="nucleotide sequence ID" value="XM_003061954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N1Z5"/>
    <dbReference type="GeneID" id="9687440"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51789"/>
    <dbReference type="eggNOG" id="ENOG502S883">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="196633at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019634">
        <property type="entry name" value="Uncharacterised_Ycf49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33833">
        <property type="entry name" value="NUCLEOLAR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33833:SF3">
        <property type="entry name" value="YCF49-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10693">
        <property type="entry name" value="DUF2499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="281" mass="29575" checksum="9E51D05539123948" modified="2009-05-26" version="1">MERPSGNREWRSLSYAMTPFLASAFSACAFHLFYNAPAINALVPLQALATFGGNVGCAVAAYRISNFNGAVDSASARASDDGESTANRRQKPSWAPTPNVFFPVKLGVSSVLAACVVKYGSLAAPAHAFLSTPTYPKALACIFIPTLAWSAVVFGGDAIASGGNEKKDSDSFWSELSMEKVKTYGKSGTIAYVVVELAFWAIAFPAAVAWYRVADGQWLDLSDPADKAKLVGAGAVFINGVRALVPLRLASAIALAPYVEEVLGGGGGEDEEEEEDSNTNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>C1N298</accession>
    <name>C1N298_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_51903</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062255.1">
        <property type="nucleotide sequence ID" value="XM_003062209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N298"/>
    <dbReference type="GeneID" id="9687492"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51903"/>
    <dbReference type="eggNOG" id="ENOG502SYQH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="501164at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025487">
        <property type="entry name" value="DUF4379"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14311">
        <property type="entry name" value="DUF4379"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="30"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Treble clef zinc finger" evidence="1">
        <location>
            <begin position="108"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="174" mass="20378" checksum="F80D3999BEA4DB3D" modified="2009-05-26" version="1">MVKKRESKQRTRGKAFFQWCKENGERGERLANEFKDPDKLPTEVTKGSWYKALWKCQKCKHAWKATVKNRTKSDKPTGCPKCVHLAPLSKTNNFLVWCEKNGERGKKLLKEYVDPDKKPTELTKWSRHKAMWKCQKCTHAWGAMVCNRTKSDKPTGCLKCHLRARQPEKRNRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2C7</accession>
    <name>C1N2C7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxoprolinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_51932</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxoprolinase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062063.1">
        <property type="nucleotide sequence ID" value="XM_003062017.1"/>
    </dbReference>
    <dbReference type="STRING" id="564608.C1N2C7"/>
    <dbReference type="GeneID" id="9687712"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51932"/>
    <dbReference type="eggNOG" id="KOG1939">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TDCNVML"/>
    <dbReference type="OrthoDB" id="3643at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF2">
        <property type="entry name" value="5-OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="5">
        <location>
            <begin position="66"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="3">
        <location>
            <begin position="310"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase B/oxoprolinase" evidence="4">
        <location>
            <begin position="865"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="824"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1106"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1345"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1396"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="834"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1365"/>
            <end position="1381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH53775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1415" mass="150416" checksum="59DDBEB4970281DE" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2P7</accession>
    <name>C1N2P7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_51613</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663745">
        <property type="protein sequence ID" value="EEH53623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003061911.1">
        <property type="nucleotide sequence ID" value="XM_003061865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2P7"/>
    <dbReference type="GeneID" id="9687351"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51613"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH53623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="51" mass="5830" checksum="323148342DED1501" modified="2009-05-26" version="1">MGRVLGLAERLWAGFSYSRKQCLANESALFDHLLKDRVRSLDLTPHQTATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N2X3</accession>
    <name>C1N2X3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_51953</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062281.1">
        <property type="nucleotide sequence ID" value="XM_003062235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N2X3"/>
    <dbReference type="STRING" id="564608.C1N2X3"/>
    <dbReference type="GeneID" id="9687948"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51953"/>
    <dbReference type="eggNOG" id="ENOG502R77W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF31">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN YCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="47"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="445"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="467"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH53100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="483" mass="50919" checksum="C1AEDE319057DE72" modified="2009-05-26" version="1">MRVPSTDGVVLAVHDHGVVTRAADGASSSSSKSPKETTTKTSDLVTLLLAHANGFHGRVFDPVVDAMTRARNLPFDVRVVAFDFRGHGRSSAPTTTPSAEDSYRWEKFAEDARAVVANLNLRGACVGVGHSLGAHALLRAEAADPGTFSSVHAYEPVFVVSADRVPGPPAPPANLAAAASRRRETFESREDALRAYASKPPLSALRRDALEAYVDHGFVDAEAEAADAKEKKLTKGGRRDGGGDAAAAVDRARGPVTLACPRDVEALVFERGGEERDAIAIVSGGRSAWDGGDKGGDRTGGGSDSASFGRRATVRYFGARCPVTISRGAATDPRDRSKGMYASAIAPVVAGDLGDNARVETHDALGHFGAFYTLVPIRPRSRGERRFLRTFPGASLRLPLAFNPRPRRLSTPTDAFQLHPDIRSYGTTLRPAGGPGDVRGERVEARGVGGGRRGGGGDGGGRRGRTDRRQGAEPDVRGCACRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1N301</accession>
    <name>C1N301_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_51982</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062525.1">
        <property type="nucleotide sequence ID" value="XM_003062479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N301"/>
    <dbReference type="GeneID" id="9687965"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_51982"/>
    <dbReference type="eggNOG" id="ENOG502RZ76">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NDHVMQK"/>
    <dbReference type="OrthoDB" id="10267381at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052164">
        <property type="entry name" value="Anthracycline_SecMetBiosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33993:SF14">
        <property type="entry name" value="GB|AAF24581.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33993">
        <property type="entry name" value="GLYOXALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="4"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="162" mass="16959" checksum="359D55A2C98C7320" modified="2009-05-26" version="1">MSALLRHVLLLQRDVPAAAAFYNKGLGLVVEVCTDAYAELSEPRGAQTGGGDAHTDRSPPSSSSSPSPSPSLPRDGGRVVLALKRVEAEAHLTTGYSPILNFTVTDMQDTVQSLIEAGARMDGGIKYLTQGKVAAFRAPDGHMLGLFEPAEGSILAGKRPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>C1N318</accession>
    <name>C1N318_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_42091</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062532.1">
        <property type="nucleotide sequence ID" value="XM_003062486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N318"/>
    <dbReference type="GeneID" id="9687742"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_42091"/>
    <dbReference type="eggNOG" id="ENOG502RZEE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LNTAYVM"/>
    <dbReference type="OrthoDB" id="497944at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH53351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="413" mass="44062" checksum="40835146A806BF78" modified="2009-05-26" version="1">MDVASLAAATTPLAVALLLAHHAELVATLVAPNARRLFAPRYGRSHRLAGVVYLVVLAIGLCDVAATVVATRAWGPRGAAGVFSTISPFPMGPNARVAHDVALGVAGVILTVTAARDFGRAHASARVKNVASGALDEDDTVTREEMLEHAFYQGLNLAQVLFLRATTSTAMRSCGQTPSALLLLLLVTSAWLLRPLFPVNRFSHNYTRAGRDPRALTSVLYRVKKYQYVFYKHFLLHGLNVTAAVSAAAATSNAATPPSFNPLRPDDVVFRTYWLGLNAAYVMEFFLQTLVKRKYASQSRMLRMNVALMVITTAPAVVVLAGVCLPAAVVSLALNFFSPGRELGNVALATCAAMLSRGGGSWWGDDDRGGAGGGWDARVVAGVFVCGVGPFRWIEAFARGRIAALRARAAKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3B5</accession>
    <name>C1N3B5_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mannosyltransferase</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_52108</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 22 family. PIGZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062350.1">
        <property type="nucleotide sequence ID" value="XM_003062304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3B5"/>
    <dbReference type="STRING" id="564608.C1N3B5"/>
    <dbReference type="GeneID" id="9688021"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_52108"/>
    <dbReference type="eggNOG" id="KOG4123">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="HPDEYHQ"/>
    <dbReference type="OrthoDB" id="10066429at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF3">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="598"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH53169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="772" mass="80095" checksum="94B5F499DADCA629" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3I4</accession>
    <name>C1N3I4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_68654</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062618.1">
        <property type="nucleotide sequence ID" value="XM_003062572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3I4"/>
    <dbReference type="GeneID" id="9688058"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68654"/>
    <dbReference type="OrthoDB" id="503261at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH53437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="169" mass="19236" checksum="34DAF167A9FC7882" modified="2009-05-26" version="1">MARARLSESVVAVVVAVGERLDHRDVDVHVHVSRRVRHRKRKRSRRERFKHRGRRDARGCPRRRQRVGGVERPRRRRSRLAERAPGAPHVVPLGTELGCVLGVMISWRAYVKVIGLMGWWREGRTRSEREEEDWKFFFDALAAAAVVAVAGGVLDFVLAGGGEWGGSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1N3V2</accession>
    <name>C1N3V2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="3">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUCDRAFT_21709</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3"/>
    <dbReference type="EMBL" id="GG663746">
        <property type="protein sequence ID" value="EEH53499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062680.1">
        <property type="nucleotide sequence ID" value="XM_003062634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N3V2"/>
    <dbReference type="STRING" id="564608.C1N3V2"/>
    <dbReference type="GeneID" id="9687878"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_21709"/>
    <dbReference type="eggNOG" id="KOG1528">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WRIQQEW"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01517">
        <property type="entry name" value="PAP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000003">
        <property type="entry name" value="PAP-specific phosphatase HAL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006239">
        <property type="entry name" value="DPNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01330">
        <property type="entry name" value="bisphos_HAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF17">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEH53499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="418" mass="43794" checksum="381CAC7C4BFDB775" modified="2009-05-26" version="1">MALRAILARSSSHPAAPPPSSPTPSPTTVTAIRAASAAKPAPASSPAGGAYALELEVGLDAVRMASTLCEEVQAQLMRQDETADTKDDRSLVTLADYAAQAIIAWRIQQEWPDFTMVGEEDAEALTEGGEGGAQTLEKITALVNKTLAKHKGDAAPTLSSTEIVAAINKGGGKGGKGRHWILDPVDGTLGFVRGDQYAIALALMEDGDLKVGVMGCPNMPKTGEVLEYDSSYTYGFSPSMVTKMLAGESVGWYKGCIFAAVKGRGCTVEPCDARIKAAPTPVTVSDAFDPVSAKFCEPVMKANSSQGFTASVADNLGIASKPLRVYSQVKYGSVARADADVFMKFPKAGYKEKIWDHAAGVIIVEEAGGKVTDAGGAPLDWAGGRYLDTLDRGIVATSAALHERLMDAVSKSWSSSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4C5</accession>
    <name>C1N4C5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_66731</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062764.1">
        <property type="nucleotide sequence ID" value="XM_003062718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4C5"/>
    <dbReference type="GeneID" id="9688417"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66731"/>
    <dbReference type="OMA" id="WRKGAFE"/>
    <dbReference type="OrthoDB" id="425020at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="100" mass="10812" checksum="B9CD72D60622EC94" modified="2009-05-26" version="1">MLISKADEAHPGKFDWTYNVDSVLRATVPNGKGWAIENQAEKPIPGGENALWRKGAFEVLRTDTNELLYSKMAEGSHLVDGKGGPEGKLGSFINDVLANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1N4D7</accession>
    <name>C1N4D7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_22036</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG663747">
        <property type="protein sequence ID" value="EEH52920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003062981.1">
        <property type="nucleotide sequence ID" value="XM_003062935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N4D7"/>
    <dbReference type="STRING" id="564608.C1N4D7"/>
    <dbReference type="GeneID" id="9688212"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22036"/>
    <dbReference type="eggNOG" id="KOG2914">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="AFEDSIW"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07505">
        <property type="entry name" value="HAD_BPGM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051600">
        <property type="entry name" value="Beta-PGM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46193">
        <property type="entry name" value="6-PHOSPHOGLUCONATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46193:SF18">
        <property type="entry name" value="HEXITOL PHOSPHATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH52920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="233" mass="25419" checksum="68A3312BC88B99CB" modified="2009-05-26" version="1" fragment="single">DGTLTDTDPIHHAVFSDMLLKDNKNGGVPIDDAFFRAHIAGRTNEDIFAALWPELSLDARKEMWEEKEAEFRRRAASQLTRLPGLTDLLTWVNMRGVRKVAVTNAPRANAELMLRALRLENYFEARSILHWSPYDPAVICGVECSRAKPHPEPYLEGLKAIGAVTPELVDRCVAFEDSPTGAMAAVRAGIATVGILTAQPAAALYDVGASLCVKDFAAGELLEAISGEDSLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1N5R7</accession>
    <name>C1N5R7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53011</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663748">
        <property type="protein sequence ID" value="EEH52546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063410.1">
        <property type="nucleotide sequence ID" value="XM_003063364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N5R7"/>
    <dbReference type="GeneID" id="9688849"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53011"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="138" mass="14031" checksum="A4C6CE85C0724029" modified="2009-05-26" version="1">MARTYARASVVNVAGDLVVSLAFTTLAVRSMSAMRAEARRVVAEERRRDAVAAAAAAEARADGKDAPPESDPPSLPAIGPEMLRTYAKLVAGHVVRGAAILAGGAVGCGAASAWRFDGGEAAEARPGHTGPHTIASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>C1N6L8</accession>
    <name>C1N6L8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_65710</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH51946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063573.1">
        <property type="nucleotide sequence ID" value="XM_003063527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N6L8"/>
    <dbReference type="GeneID" id="9689014"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_65710"/>
    <dbReference type="eggNOG" id="KOG0059">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="563"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="9">
        <location>
            <begin position="356"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH51946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="656" mass="68006" checksum="5C003110EC8DE1F6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1N719</accession>
    <name>C1N719_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_22820</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063654.1">
        <property type="nucleotide sequence ID" value="XM_003063608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N719"/>
    <dbReference type="GeneID" id="9689095"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_22820"/>
    <dbReference type="eggNOG" id="ENOG502SD5W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LMWKYQQ"/>
    <dbReference type="OrthoDB" id="9981546at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016857">
        <property type="term" value="F:racemase and epimerase activity, acting on carbohydrates and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052996">
        <property type="entry name" value="Carb_Metab_Mutarotase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008000">
        <property type="entry name" value="Rham/fucose_mutarotase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43239">
        <property type="entry name" value="UPF0734 PROTEIN DDB_G0273871/DDB_G0273177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43239:SF1">
        <property type="entry name" value="UPF0734 PROTEIN DDB_G0273871_DDB_G0273177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05336">
        <property type="entry name" value="rhaM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH52027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="125" mass="14361" checksum="148C6FF07B89A2FE" modified="2009-05-26" version="1">MTKHYAQTICLRDGAGVVDEYKAYHAEAWPEVCDALSAVGVEEMRIWLVGRRLFMAMSTSDAFDPEVDFPRHMAMSPRCVEWGARMRAFQTPPPEAMEGDWWTYMECVFDLGARDRSKPGYRNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1N795</accession>
    <name>C1N795_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_53604</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663749">
        <property type="protein sequence ID" value="EEH52071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003063698.1">
        <property type="nucleotide sequence ID" value="XM_003063652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N795"/>
    <dbReference type="GeneID" id="9689300"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53604"/>
    <dbReference type="eggNOG" id="ENOG502RADN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40021at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032723">
        <property type="entry name" value="Deaminase_LmjF365940"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14421">
        <property type="entry name" value="LmjF365940-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH52071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="702" mass="74116" checksum="8707DC898CA857E4" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7M3</accession>
    <name>C1N7M3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_23057</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064122.1">
        <property type="nucleotide sequence ID" value="XM_003064076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7M3"/>
    <dbReference type="STRING" id="564608.C1N7M3"/>
    <dbReference type="GeneID" id="9689370"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_23057"/>
    <dbReference type="eggNOG" id="KOG0591">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NNKDIWA"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF7">
        <property type="entry name" value="NIMA-RELATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="4"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH51744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="257" mass="28933" checksum="96CB667BE5483D36" modified="2009-05-26" version="1" fragment="single">MDDFSVVRKLGRGSFGEVFACVRRDDPSRRLVVVKKITMGAKRSDQEDAMNECRVLAKLDSPYVTKYYDSFVENGGKELCIVMEYAPKGTVHQLVRASPPGRLDESTIWKLTLQSALGLHHIHRLKILHRDIKSENIFLDARGDAKIGDLGVAKVMSHEGSLARTLVGTPYYLSPELCENKPYDHKSDVWSLGCVIYEMLTGTHPFHGDNQGALFMKILRGKYPPVNERAYGEDIRALLDRCLANDVRTRLDARGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1N7Z6</accession>
    <name>C1N7Z6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_53888</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663750">
        <property type="protein sequence ID" value="EEH51803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064181.1">
        <property type="nucleotide sequence ID" value="XM_003064135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N7Z6"/>
    <dbReference type="GeneID" id="9689622"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_53888"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="135" mass="15172" checksum="7A29B34BCACFF0A5" modified="2009-05-26" version="1">MSTPRRRRRDVASSDHSTDADLDELRRRSSEIEGVDRSDAHEAARLSNLIFERTRAYRLAIIRPYANVHRTGLWIAFAAFTAAGWKDVRSGVSLGPVPIRSPLGYLVAYAWALAFLAALVFKVRDVINHHVITTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8P7</accession>
    <name>C1N8P7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_49176</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064312.1">
        <property type="nucleotide sequence ID" value="XM_003064266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8P7"/>
    <dbReference type="STRING" id="564608.C1N8P7"/>
    <dbReference type="GeneID" id="9689925"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49176"/>
    <dbReference type="eggNOG" id="ENOG502QQ68">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MVADSNH"/>
    <dbReference type="OrthoDB" id="507831at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002912443" evidence="1">
        <location>
            <begin position="41"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="285" mass="29367" checksum="11D3B9E9B3CDE738" modified="2009-05-26" version="1">MTAAAAATTTTRRRSTTTISSFLLSLACAVLVVAPSPARAAGIYDPCVAQSAVQIGDTFSIGIAFYPGGAISDWYDSAGKIYHPCDATASAVLQTKLVQTQSFRPKVDHLTFLRGDATEETAVFNTASGTPIIMTMVAYTANGIISDPRIVRVTNSGAIVGGSDLGRVSSLTLVARFDGGNVAHLQWHDIGCSSCKDGDSCINVDAKGDHYACAGSETACSCTGSGCALNLAGTDVLRCQLTTSLGFSGTDKHSVPMKSGAQIERLGQYSIEEAADGAGASAYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8V7</accession>
    <name>C1N8V7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_37010</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064516.1">
        <property type="nucleotide sequence ID" value="XM_003064470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8V7"/>
    <dbReference type="STRING" id="564608.C1N8V7"/>
    <dbReference type="GeneID" id="9689781"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37010"/>
    <dbReference type="eggNOG" id="KOG1427">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GKWKNTG"/>
    <dbReference type="OrthoDB" id="297375at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028641">
        <property type="entry name" value="RCC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46207">
        <property type="entry name" value="PROTEIN RCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46207:SF1">
        <property type="entry name" value="PROTEIN RCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="79"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="136"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="202"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH51421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="361" mass="37947" checksum="0DF57BCDB1EB7C52" modified="2009-05-26" version="1">MKGVPIVAVCGGAAAAHAIAIAEDGRVFAWGRNENGQLGLGDTVDRGIPTVIKELQDKGAKAIDGACGKHHTVILCEGGVTYAFGSNKHGQLGIGTIARKAREDDVRTTPVQTQVANATAVACGGEFTMWIAGENGALYSAGLPQYGQLGHGSDHEYNMKEGSVKLAYQPQPSPRAIAALSDKKIIRVACGHNHTICVDSVGKVYTWGFGGYGRLGHKVQKDEFAPKQVEVQGGDRNLCPPDCVVAAGSVTSWFTALMGQMYCFGKLKTNGDNTMYPIPFLDLQGWNLRSVACGATTFAACGEREAITWGQGGGNGELGYGASGPKSSANPKLVDSLSGKMVHRVRRVLSHTGPRTTASAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1N8V8</accession>
    <name>C1N8V8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_49767</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 14-3-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663751">
        <property type="protein sequence ID" value="EEH51245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064340.1">
        <property type="nucleotide sequence ID" value="XM_003064294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N8V8"/>
    <dbReference type="STRING" id="564608.C1N8V8"/>
    <dbReference type="GeneID" id="9689958"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49767"/>
    <dbReference type="eggNOG" id="KOG0841">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="KGCQLAR"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000001">
        <property type="entry name" value="14-3-3 gamma 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="12"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="264" mass="29850" checksum="F239B69BA525B121" modified="2009-05-26" version="1">MNAPEDLSGLSRPDLVYKAKLAEQAERYDEMMEYMSKVAEQSTSSSPPEELSVEERNLLSVAYKNVIGARRASWRIVSSIEMKEEGKYSKESDTVKLIAKYKEGVEKELGNICDRVLKLLKDHLEETSSAGESKVFYKKMKGDYYRYLAEFKGGEARKNAAEETLLAYKEAENIASNELAPTHPIRLGLALNFSVFYYEILNAPERACDMAKKAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMAEEQPGGEKEEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9Q5</accession>
    <name>C1N9Q5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_54583</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064775.1">
        <property type="nucleotide sequence ID" value="XM_003064729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9Q5"/>
    <dbReference type="GeneID" id="9690097"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54583"/>
    <dbReference type="OMA" id="YLCAHPS"/>
    <dbReference type="OrthoDB" id="10632085at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="123"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH51109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="170" mass="19129" checksum="B2FDA26B62B3EBAE" modified="2009-05-26" version="1">MPRTPPSRGRDYRGDRTTPRRGPRSESEYSEYSEDGPTLFGSLLRTLMAGGAVVAVAILVRDAARLHSFVRVRFDSTRRPVPRTGRFPAYLCAHPSRSIPTHLDAFQRHLTPLNLTPTSSLVWTLDPQEGDCLYRIAVNRGIDPDALERMNPELASRPHYLQPGELVRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1N9W1</accession>
    <name>C1N9W1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_54662</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064801.1">
        <property type="nucleotide sequence ID" value="XM_003064755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1N9W1"/>
    <dbReference type="GeneID" id="9690242"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54662"/>
    <dbReference type="eggNOG" id="ENOG502S6TC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WRMTYLD"/>
    <dbReference type="OrthoDB" id="189024at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="4">
        <location>
            <begin position="72"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH51135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="239" mass="24956" checksum="18CC31CBC02B2AE3" modified="2009-05-26" version="1">MRAAVASLALPAVAPSRSSRSSPSPSSRRRPSPASSRARRRSSAIASSSSSSDATASTQIAALAGRLRAEAGDANGVDRDETQRASIARIIAEIDALNPTRDTAAVDLAGTAWDLVYTDSQGNSSGKIGPFVGAVTQIFDADADPKKPGSGSTYANIVTFGPARLKLRAVAEGVAKKPTTLKVTFEDVTAEVFGRDVFAKPFPKGRAGTWTVTHASEALRVLRTNQGNVFVLAKQRESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1NA64</accession>
    <name>C1NA64_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_43700</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064737.1">
        <property type="nucleotide sequence ID" value="XM_003064691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NA64"/>
    <dbReference type="STRING" id="564608.C1NA64"/>
    <dbReference type="GeneID" id="9690294"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_43700"/>
    <dbReference type="eggNOG" id="KOG0065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WHVQMGH"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF91">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="479"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="516"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="544"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="570"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="613"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="59"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH51071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="642" mass="70795" checksum="DE96F314418E2C95" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAA2</accession>
    <name>C1NAA2_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">sulfate adenylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-sulfurylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Sulfate adenylate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_30508</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="2"/>
    <dbReference type="EMBL" id="GG663752">
        <property type="protein sequence ID" value="EEH51202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064868.1">
        <property type="nucleotide sequence ID" value="XM_003064822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAA2"/>
    <dbReference type="STRING" id="564608.C1NAA2"/>
    <dbReference type="GeneID" id="9690201"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30508"/>
    <dbReference type="eggNOG" id="KOG0636">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IEIYKHH"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00517">
        <property type="entry name" value="ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.10">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002650">
        <property type="entry name" value="Sulphate_adenylyltransferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00339">
        <property type="entry name" value="sopT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43509">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43509:SF1">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-sulfurylase PUA-like" evidence="11">
        <location>
            <begin position="20"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Sulphate adenylyltransferase catalytic" evidence="10">
        <location>
            <begin position="184"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH51202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="398" mass="43516" checksum="A494B0CC5FF58CB7" modified="2009-05-26" version="1">MNHRGFFASSRAASGAGSLIAPHGGSLVNLMVSDAAKAAAIVASATRSLELSHRNACDVELLATGGFSPLRGFMNEDVYAHCVENMRLPGSNLLFGMPIVLDTDCEDTKVGDKVVLKYQGKDVAVVTVESKWKPNKPLEAKMCYGTSSIEHPGVSMISMERRKYYIGGAVEAVSVPERPFPCPSPAEVRAMLPEGKDVVAFQCRNPIHRAHYELFTRALHADNVGEGAVCLVHPTMGPTQDDDISGLVRYHTYEVLAKEVNNPAIRWAYLPYSMHMAGPREAIQHMIIRKNYGCTHFIIGRDMAGSKSSIDGEDFYGAYDAQDLAKANAAELGMKTVPSLNVVYTDEEGYVTADVAEKKGLSVKKLSGTKFRKMLRGGEDIPEWFAFKSVVNVLREHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAD9</accession>
    <name>C1NAD9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_54862</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064946.1">
        <property type="nucleotide sequence ID" value="XM_003064900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAD9"/>
    <dbReference type="GeneID" id="9690329"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_54862"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH50926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="114" mass="12043" checksum="9BCA3926C4221948" modified="2009-05-26" version="1">MEAYMIAIRVKGEALHRESGAGTRAEPRAGSDEGLLHQIQLMLDNLAATPASEGGGGGNASAIESLTQHDHQGHTTQSQQLLVQLLRGVRPAYSYSFVTSTHFFSRAELPAGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1NAJ5</accession>
    <name>C1NAJ5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_66099</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663753">
        <property type="protein sequence ID" value="EEH50950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003064970.1">
        <property type="nucleotide sequence ID" value="XM_003064924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1NAJ5"/>
    <dbReference type="GeneID" id="9690361"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_66099"/>
    <dbReference type="eggNOG" id="ENOG502S980">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="521976at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH50950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="368" mass="41479" checksum="AD378F9EE911B484" modified="2009-05-26" version="1">MGSTRSLVRRGTFLGYSFLAACLICLYVFFRQGTGSKINTPDLRVVVKTTYRPSALEQYIMDGRKTFGYILFNDDYASGCEVWKSPPSEIADILTAFAEELKSYSAWADSFESFDLKTDLRTHRAADRGRVCNRLQPAIGLNQTFQSGALSCTSSGYLEPILPPMRHPEFCFDGNLLMSTKYLVHDFPALCSRLSANSRTVFVDLGASLVFHADGEQPTLSLIKLYQKFGFYFDHIYAYEITPGNATELYESLPAEWLASYHWINAGIETDPTSALNPLRMLIENYEPGDLVVLKIDVDNPEVELSIINQILTNEALHGLIDQLYFEHHVLLEELRVPWGPSVRGSVSDSLILFHELRSQGISAHFWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRB3</accession>
    <name>C1KRB3_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Elongation factor Tu, chloroplastic</fullName>
            <shortName evidence="10">EF-Tu</shortName>
            <ecNumber evidence="10">3.6.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tufA</name>
        <name evidence="13" type="ORF">MicpuC_chl6</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="13"/>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">GTP hydrolase that promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="function">
        <text evidence="1 11">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Plastid</location>
            <location evidence="10">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 11">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="10"/>
    <dbReference type="EMBL" id="FJ858269">
        <property type="protein sequence ID" value="ACO50745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRB3"/>
    <dbReference type="STRING" id="564608.C1KRB3"/>
    <dbReference type="OMA" id="KTHANIG"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03707">
        <property type="entry name" value="EFTU_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000001">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000046">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000003">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF5">
        <property type="entry name" value="ELONGATION FACTOR TU, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 10 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="9 10 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 13" id="KW-0934">Plastid</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="12">
        <location>
            <begin position="10"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACO50745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="409" mass="44226" checksum="25F028C929335A86" modified="2009-05-26" version="1">MAREKFERTKPHVNIGTIGHVDHGKTTLTAAITMAMSAKSGGAAKGYADIDSAPEEKARGITINTAHVEYETEGRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSGADGPMPQTKEHILLAKQVGVPNVVVFLNKEDQVDDDELLELVELEVRDTLSSYEFPGDDIPVVAGSALLALEALTETPAMASGDNKWVDKIFALMEAVDSYIPTPERDTEKTFLMAIEDVFSITGRGTVATGRVERGTVKVGDVVEIVGLGDTREVTVTGLEMFQKTLDESVAGDNVGVLLRGIQKDDIERGMVLAKTGTITPHTKFESQVYVLTKEEGGRHTPFFPGYRPQFYVRTTDVTGKIESFRSDDGDEATMVMPGDRVKMIVELIQPIAIENGMRFAIREGGRTVGAGVVSAILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGM7</accession>
    <name>C1MGM7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Intraflagellar transport protein 57</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IFT57</name>
        <name evidence="7" type="ORF">MICPUCDRAFT_13268</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IFT57 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055347.1">
        <property type="nucleotide sequence ID" value="XM_003055301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGM7"/>
    <dbReference type="STRING" id="564608.C1MGM7"/>
    <dbReference type="GeneID" id="9680539"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_13268"/>
    <dbReference type="eggNOG" id="KOG0972">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VHAHDQD"/>
    <dbReference type="OrthoDB" id="423881at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019530">
        <property type="entry name" value="Intra-flagellar_transport_57"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16011">
        <property type="entry name" value="IFT57/HIPPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16011:SF0">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 57 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10498">
        <property type="entry name" value="IFT57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="151"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="297"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH60599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="399" mass="44051" checksum="EC1F17C71BD74054" modified="2009-05-26" version="1">MELILEKLKLLNYETEFCAKRKPPWPRLTRATFAIAESSSSDRDARFHHYAALAAFLVQLCGRRGHLAPGESDDQKTSAAAILHECAKLGFDPPEFSPSALTRASGKEAVGVLNGLCDLALERAMPRLRRPKHAKEDPPEMATYEAHEGAFESGGEGARLGRGAFADDDAENDDDDASDSDASEEAYIIEDARAIESHVDAAAWKLELERVAPQLRVVAAADAKDWRAHLESAREHRRSIAGTFPDVRVMLDGVVKDVAGALEKIETREAYVNAQLAPLADEYRTRREKLDETQRAYDAASEATSSMTNELARLTEELEKVKGVIEDRGENNADATPLNTMKENMEKMREEIKVFEVRVAVCRSALLKHEVKRQAAIVAGKKAGGKKKRRPGADDDTPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MGR6</accession>
    <name>C1MGR6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_46129</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055366.1">
        <property type="nucleotide sequence ID" value="XM_003055320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MGR6"/>
    <dbReference type="GeneID" id="9680623"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46129"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH60618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="164" mass="16696" checksum="1D3BC0F7CAFE1B62" modified="2009-05-26" version="1">MADNLVPVTRSGDDDEAIDEDLERMDLGGAWWHLGGDDAPNAPMHVVGVDFRDGGWSGVGGGGLVLRFATDGARAADASSSRGVFSASVAGKLAGARAADAAMDVDAYANAAVVPAHHVSSALIKVEPPTVARAAADRVVVDASNNGGISYSDGRIRYHKSAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHC0</accession>
    <name>C1MHC0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_46207</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003054930.1">
        <property type="nucleotide sequence ID" value="XM_003054884.1"/>
    </dbReference>
    <dbReference type="GeneID" id="9680944"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_46207"/>
    <dbReference type="OMA" id="RQMKSKM"/>
    <dbReference type="OrthoDB" id="10692866at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="783"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="871"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1024"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1109"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1224"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1399"/>
            <end position="1418"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="383"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1279"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1334"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1645"/>
            <end position="1722"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1830"/>
            <end position="1857"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1897"/>
            <end position="1947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="783"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="871"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1027"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1047"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1109"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1141"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1240"/>
            <end position="1249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1952" mass="217678" checksum="35148E6DD4DC72B1" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHT0</accession>
    <name>C1MHT0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50309</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055546.1">
        <property type="nucleotide sequence ID" value="XM_003055500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHT0"/>
    <dbReference type="STRING" id="564608.C1MHT0"/>
    <dbReference type="GeneID" id="9681113"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50309"/>
    <dbReference type="eggNOG" id="ENOG502RREG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37473">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37473:SF1">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="213"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="283"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="393"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="580" mass="62696" checksum="742251A9C8920BF9" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHT4</accession>
    <name>C1MHT4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_37953</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055010.1">
        <property type="nucleotide sequence ID" value="XM_003054964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHT4"/>
    <dbReference type="GeneID" id="9680541"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_37953"/>
    <dbReference type="OMA" id="WRSEDSY"/>
    <dbReference type="OrthoDB" id="10688935at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="564"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="697" mass="72811" checksum="29FD2018C789E93E" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MHU8</accession>
    <name>C1MHU8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_30910</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG7 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055554.1">
        <property type="nucleotide sequence ID" value="XM_003055508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MHU8"/>
    <dbReference type="STRING" id="564608.C1MHU8"/>
    <dbReference type="GeneID" id="9681071"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_30910"/>
    <dbReference type="eggNOG" id="KOG4182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LKYYHNC"/>
    <dbReference type="OrthoDB" id="245173at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019335">
        <property type="entry name" value="COG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10191">
        <property type="entry name" value="COG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="530"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH60806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="809" mass="84334" checksum="05BEE5DB88CD7D75" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI01</accession>
    <name>C1MI01_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_50383</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055043.1">
        <property type="nucleotide sequence ID" value="XM_003054997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI01"/>
    <dbReference type="STRING" id="564608.C1MI01"/>
    <dbReference type="GeneID" id="9681149"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50383"/>
    <dbReference type="OrthoDB" id="10688596at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031032">
        <property type="term" value="P:actomyosin structure organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF71">
        <property type="entry name" value="CITRON RHO-INTERACTING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="370"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="474"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="556"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="667"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="758"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="925"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1044"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1097"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1178"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="725"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="126"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="370"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="556"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="627"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="670"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="759"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="769"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="829"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="842"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="925"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="949"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1103"/>
            <end position="1112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH60295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1202" mass="128355" checksum="A57E8EBA94E68BF5" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MI18</accession>
    <name>C1MI18_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50401</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055589.1">
        <property type="nucleotide sequence ID" value="XM_003055543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MI18"/>
    <dbReference type="GeneID" id="9680542"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50401"/>
    <dbReference type="OMA" id="KRCGEIM"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046466">
        <property type="entry name" value="Borealin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10512">
        <property type="entry name" value="Borealin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Borealin C-terminal" evidence="2">
        <location>
            <begin position="185"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="339" mass="33363" checksum="A62670507C0E59F7" modified="2009-05-26" version="1">MTLKQFSEDYRSEISAELLKDVEARLRAATAAAAAAAAAAGKENAPAPAPTRKRGRPTNASIAAAKAAKKEAAEKERERERQIEEAANQELSPNVSTRGGEMPPPPPMFAAPYSGGASDAARKTARTAAAAIAAGTGTLLAATPDRAKRRGAFANAAADGGSSFAVPCTPVDGRGGGAAVAAPQMPRMSVAKTPATLRRARKGEVLYSANGSPLGAADDGEGSDDDGAGAGADASKRALASAVKRVRFSTGGDGGGGGGDGDGGGAGAAHGRKASIVAMRGASEGGERSALVVTTDDGTEIDLGAVDASNGGETVDAAVGALQSLQAQVAAAMARLTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MIP8</accession>
    <name>C1MIP8_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_50648</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055703.1">
        <property type="nucleotide sequence ID" value="XM_003055657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MIP8"/>
    <dbReference type="GeneID" id="9680988"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50648"/>
    <dbReference type="eggNOG" id="ENOG502SB70">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="MWASSIA"/>
    <dbReference type="OrthoDB" id="497571at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH60955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="259" mass="27297" checksum="2A40BF0CD9E0DA34" modified="2009-05-26" version="1">MERATTAAAGCSRTALAARTRGAPATTPRTPTRTPARTRRATRRRAVSSQKGDRGDDDDDRADGNASRDALRALDKLVPGTTADEARREPPPERADGDDASTSRDEGGIGIVRREVVVELDAEDANVAMASFAVRSASARIVQVTIPPPVGIAFEEDDDDGEIVVAEVVEGSNAAAVGGVAVGDVLRATSAMIPEMKYPMGNLFLGGVGRPGFRRVLFTIPVGEAYAPGATFDDAMGAIFSNKKAGDFDVVLVLERRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJE2</accession>
    <name>C1MJE2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_50907</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663735">
        <property type="protein sequence ID" value="EEH60551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055299.1">
        <property type="nucleotide sequence ID" value="XM_003055253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJE2"/>
    <dbReference type="STRING" id="564608.C1MJE2"/>
    <dbReference type="GeneID" id="9680498"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_50907"/>
    <dbReference type="eggNOG" id="KOG3044">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WSKEANC"/>
    <dbReference type="OrthoDB" id="536664at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040233">
        <property type="entry name" value="CCD97-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018613">
        <property type="entry name" value="Ccdc97-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31840">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31840:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09747">
        <property type="entry name" value="CCD97-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCD97-like C-terminal" evidence="2">
        <location>
            <begin position="123"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH60551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="416" mass="44172" checksum="C134E8C2E1F24BEF" modified="2009-05-26" version="1">MAAWGALLEDDDASPTTTASVLTALASASDLRVPASVLRGDGWEDSVACRRRYVEDLYAREPSILLERHGHLVPRSRLLAAFGHLEGSSYECDFHLNRLKEGATTTTGGTGTGTGTTTATARNRRLAHMRSSLEPAGYFHEDALRRREPLLFETFVGAPARADSNSNSNLNLNSTATATATATDGAGASHAVSLAMLEREDERAAAALLSRQRAALRERERVEDIDAEDEPPLEDEPPPAAATDAASRPGVVVEAVGPGGRRGASGRATADQLRRAAVEGWARGNDDDDDADANRRLGGCEPSSCGTGTTREINRSAIASVVADPERDAKLAAFARTMRERYLGAFFTLHTDGMDPGADYAAIDADRSLDDWHAREATQDAEDAYFAEGDGYDEGGAVGGAVEGAVDSEDDSFTRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJR4</accession>
    <name>C1MJR4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="7">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_38354</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 14">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="7"/>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055866.1">
        <property type="nucleotide sequence ID" value="XM_003055820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJR4"/>
    <dbReference type="STRING" id="564608.C1MJR4"/>
    <dbReference type="GeneID" id="9681635"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_38354"/>
    <dbReference type="eggNOG" id="KOG2108">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="550469at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070:SF30">
        <property type="entry name" value="F-BOX DNA HELICASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="10">
        <location>
            <begin position="308"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="11">
        <location>
            <begin position="822"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="640"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="640"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH59242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="936" mass="99934" checksum="942CA956F9FDD70D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1MJS1</accession>
    <name>C1MJS1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PfkB family carbohydrate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_55071</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055869.1">
        <property type="nucleotide sequence ID" value="XM_003055823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MJS1"/>
    <dbReference type="STRING" id="564608.C1MJS1"/>
    <dbReference type="GeneID" id="9681888"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55071"/>
    <dbReference type="eggNOG" id="KOG2947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CIMIERS"/>
    <dbReference type="OrthoDB" id="204058at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052562">
        <property type="entry name" value="Ketohexokinase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774:SF3">
        <property type="entry name" value="KETOHEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774">
        <property type="entry name" value="PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="4">
        <location>
            <begin position="62"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="4">
        <location>
            <begin position="432"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH59245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="567" mass="59580" checksum="667333354FBAFF83" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK04</accession>
    <name>C1MK04_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55170</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056304.1">
        <property type="nucleotide sequence ID" value="XM_003056258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK04"/>
    <dbReference type="GeneID" id="9681299"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55170"/>
    <dbReference type="OMA" id="HSFRQWI"/>
    <dbReference type="OrthoDB" id="567961at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH59680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="472" mass="54234" checksum="956DA0AD8B42961D" modified="2009-05-26" version="1">MSVCGIDMSAVGMSVISGCVEHQECKVVLPLATFDLHFDRPVNVQQGSKLTSAYVPRASSDLLNNLSETFFVWLSHPSESFWVNLNPTESDRVVERNIGHTEVGRIMLEADLSLKKTAARLLHPDHPILYGSIGTRDIQICHSFRQWIVPDIAEVWQSSSGSRGYKSKQGRTDVMHRSKCEKKNVSSFHVLSARLLVKQEALYYTNAKEWEYETRAPDEDVRTLCQSSDVTTQRKADELFKASPDHKHLFYSLLTLLPAQSILLPELQRQVNENPEYLHLRAIFLWRIVSEWYQRNMKNTFDEALESKQVSCYKSRLHVWLRNNSAKSKSNCISDELTKTLNFLEPEHWYRPVSNTWMPAVVFDEYAKSMIEGEFHITRESRSVEGDVFYRTYFHGGIDFRKLFIRSADVQNLEASKKNSDLTLKWYYIYGGRGLAHADTEDTSLVPGSLGITASFSKSMMNFSYTNPNHEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>C1MK21</accession>
    <name>C1MK21_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_55188</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003055915.1">
        <property type="nucleotide sequence ID" value="XM_003055869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MK21"/>
    <dbReference type="GeneID" id="9681456"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55188"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="309" mass="33676" checksum="0B40C6FF7828FEFE" modified="2009-05-26" version="1">MRLLASTTLVIVTCCALCDYAVTLVSLTVKTPAQGLAAQRACFRISQSLLTLDRLGPTRVYDAVVFTIRAVSITSGGITTAVFLTISHLLAAASRRKHMSPEAKKLVRLAGAWLNMASVTWAFISLLRHVPGFCPVCEKNGSPDVNVIGGYSLDKPTTTGGTLSNLGLVKNARRRRELTTLRNITFISCYDGDTCFFTLPEVVEHVPELAPLFGARIAVRIYGIDCPELGGRAKCARERQLAIRARDVADSMLRSAISLQVTDARPDKFFRVLGRLILNNSVELGKELVRGKLAVEYSGKARSGETWCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKI2</accession>
    <name>C1MKI2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_49432</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056390.1">
        <property type="nucleotide sequence ID" value="XM_003056344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKI2"/>
    <dbReference type="STRING" id="564608.C1MKI2"/>
    <dbReference type="GeneID" id="9681954"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49432"/>
    <dbReference type="eggNOG" id="KOG1607">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ESMWKFA"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005225">
        <property type="entry name" value="LAG1_LAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="90"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="321" mass="37145" checksum="88B9545F0FC57116" modified="2009-05-26" version="1">MHKIAGWSTVTAETKWIISAFFHQLRGTVSKAKLRPPIIEGHTDVLVFLLLSFILFLFNWALRIFFVEPVAAQLLGKWSTRAKVQKFAQSSLEMFFYLTFSSFGAIIVPRQDWFWTPSLWFKEFHSGKMIYISDALKAYYVLYAARYGQGLVSLLVEHKRKDFREMALHHFVTVWLIGLSYTYGWTRVGAVVMVLLDPADVPLHIAKQFKYVGDVRGGARKKSCQAAADFFFMVFMFLFAIMRLGLYPYVVWTAHRESAPYWKQQIGGRTCIILLYVLLALQIYWFTLVLRVAIKVITCGSAEDVRSDDDEDDSSEHKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MKW4</accession>
    <name>C1MKW4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_64666</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056456.1">
        <property type="nucleotide sequence ID" value="XM_003056410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MKW4"/>
    <dbReference type="GeneID" id="9681370"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_64666"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2700">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH59832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="635" mass="68751" checksum="40884C5DEC2C6A2D" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLK4</accession>
    <name>C1MLK4_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_55745</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056580.1">
        <property type="nucleotide sequence ID" value="XM_003056534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLK4"/>
    <dbReference type="STRING" id="564608.C1MLK4"/>
    <dbReference type="GeneID" id="9681598"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55745"/>
    <dbReference type="eggNOG" id="KOG2456">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PCIQGQV"/>
    <dbReference type="OrthoDB" id="440325at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="70"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH59956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="547" mass="60062" checksum="9C76A365E7EAAB09" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1MLM0</accession>
    <name>C1MLM0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_31954</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663736">
        <property type="protein sequence ID" value="EEH59965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056589.1">
        <property type="nucleotide sequence ID" value="XM_003056543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MLM0"/>
    <dbReference type="STRING" id="564608.C1MLM0"/>
    <dbReference type="GeneID" id="9682047"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_31954"/>
    <dbReference type="eggNOG" id="KOG3146">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="FLCANCF"/>
    <dbReference type="OrthoDB" id="302705at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042392">
        <property type="term" value="F:sphingosine-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF13">
        <property type="entry name" value="AT30094P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="2">
        <location>
            <begin position="47"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="244" mass="26912" checksum="1C56C7265B80B84D" modified="2009-05-26" version="1">MKPFNLTYVRYPPDDVVGSLMAVASLVPIAGILATSGVFFARRELWDILTLAGTLFCEVVAQILKWWAKDPRPSSCAVVDFCGTYGMPSSHAQLAAFSATINSLHLYRRLRGCRLRGDETSITTLHLQRLDPLVIASVSSSWPVAFVVAVSRVHLGYHSFEQVCVGFAIGFGLGIVWHAASCVIAAAAKEGLECRVVSNKNFCSVLWTKAVEFLNLRDSSLVSNPLEFQRQLFVQYAERRVVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MM15</accession>
    <name>C1MM15_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_56363</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057316.1">
        <property type="nucleotide sequence ID" value="XM_003057270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MM15"/>
    <dbReference type="GeneID" id="9682299"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56363"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1048"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1048"/>
            <end position="1071"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH58961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1079" mass="115777" checksum="AB1B68FF3DBC49A6" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMG1</accession>
    <name>C1MMG1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_49523</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057399.1">
        <property type="nucleotide sequence ID" value="XM_003057353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMG1"/>
    <dbReference type="STRING" id="564608.C1MMG1"/>
    <dbReference type="GeneID" id="9682838"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49523"/>
    <dbReference type="eggNOG" id="KOG1973">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3038">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="QEWIVAT"/>
    <dbReference type="OrthoDB" id="10265994at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17015">
        <property type="entry name" value="ING_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20393">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20394">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037802">
        <property type="entry name" value="SGF29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010750">
        <property type="entry name" value="SGF29_tudor-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047288">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047287">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539:SF0">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07039">
        <property type="entry name" value="SGF29_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51518">
        <property type="entry name" value="SGF29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SGF29 C-terminal" evidence="7">
        <location>
            <begin position="184"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="25"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH59044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="330" mass="35952" checksum="853830AA8C05ECE9" modified="2009-05-26" version="1">MANSIHVMTYLEKYVELSSSLPVELQRVVVTIKDLDERLSALKKETDAKVEKCLAMPSASSRQASAGDMDAINATRREIERAHADINQLSTEKVRLAGIAMEMIQFNIAKLDKELAPFSEEMKRLEGAGFEDEFGVEGMEGMDAVTMAFAMGEGGGFDDGAPGVPAQLHRAPSHKKSHKKKIPVNAPPQPGERVAANIGEVTAGEGAQEWIVAVVVQYIAEERAYEVMDADEDDPEGGGHVYHLPEHLVIPMPRSASARDGQVNLSRGTTVLAVYPATTTFYRAVVVQQAQKINGEFGEFLLEFEDDGDADGLPQRPVPFMHVVRHPSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMK1</accession>
    <name>C1MMK1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Glycylpeptide N-tetradecanoyltransferase</fullName>
            <ecNumber evidence="2 5">2.3.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_32507</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 5">
            <text>N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15521"/>
            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12667"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133050"/>
            <dbReference type="EC" id="2.3.1.97"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NMT family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.97" evidence="2 5"/>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003056942.1">
        <property type="nucleotide sequence ID" value="XM_003056896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMK1"/>
    <dbReference type="STRING" id="564608.C1MMK1"/>
    <dbReference type="GeneID" id="9682859"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_32507"/>
    <dbReference type="eggNOG" id="KOG2779">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="GWKRDWH"/>
    <dbReference type="OrthoDB" id="60315at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.170:FF:000003">
        <property type="entry name" value="Glycylpeptide N-tetradecanoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000042">
        <property type="entry name" value="Glycylpeptide N-tetradecanoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000903">
        <property type="entry name" value="NMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022677">
        <property type="entry name" value="NMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022678">
        <property type="entry name" value="NMT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022676">
        <property type="entry name" value="NMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377:SF5">
        <property type="entry name" value="GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377">
        <property type="entry name" value="N-MYRISTOYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01233">
        <property type="entry name" value="NMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02799">
        <property type="entry name" value="NMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015892">
        <property type="entry name" value="N-myristl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00975">
        <property type="entry name" value="NMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00976">
        <property type="entry name" value="NMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase N-terminal" evidence="7">
        <location>
            <begin position="52"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase C-terminal" evidence="8">
        <location>
            <begin position="225"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH58587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="419" mass="47566" checksum="2F55282FD00ADACF" modified="2009-05-26" version="1">MSDEDERPVPDLTEVQREFGGMNLSVPDHAFWETQPVGQLKPELNKAGEEGPIDDPIAVADVKQEPYKLPDAFEWSSCDLTNDTTKQEVFDLLAANYVEDDDEIFRFKYSPEFIKWATQPPGYHQDWHLGVRVKGTEKLVAFITGVPAKVMVKGKAIDLAEINFLCIHKKLRAKRLAPMLIREITRRVNLRGIWQAAYTAGVVLPRPISTGRYWHRSLNFKKLVEINFTTLHARSTMARSIKLFKLENKTRTPGLREMRDEDVPGVTVILNKYLRKFAVAPVFTEAEVRHHLSPRDGVVYSFVVEDEGKPGAVTDFVSFYSLPSTVIKNTMGHDTLRAAYSYYNVPGKTPLLDLMGDALILAKQRDFDVFNALDLMENEPEAILSALKFGIGDGNLQYYLYNWRLNEELPSSEIGLVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MMW7</accession>
    <name>C1MMW7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_56685</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH59124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057479.1">
        <property type="nucleotide sequence ID" value="XM_003057433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MMW7"/>
    <dbReference type="GeneID" id="9682918"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56685"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910345" evidence="2">
        <location>
            <begin position="27"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH59124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="285" mass="30153" checksum="8252D2D2B6D6A2B9" modified="2009-05-26" version="1">MALPRRAPFALALLLLLLAPREGARASDRGLCFVLPDASSSSSSSSSSRVRPRPNARVDADALAATATRCVTHPRLDLQAAHARLRVVDARDADATRVALRCERAFTSFLCDRALAPRSANDDDDDDDDDAFPAFSCEAIDPAVAVAEEEEEEETAGSGANDASMETCVWPVCETLCVGSPSASRAKTTRDAKSFASTCARCARACDVTRTGATIGILTEPTTPGDRYCAALARQRARGGARSAAPRREARSGVAPDFGGGDDGGEVRSIHWSPYDRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNI9</accession>
    <name>C1MNI9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_55916</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057112.1">
        <property type="nucleotide sequence ID" value="XM_003057066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNI9"/>
    <dbReference type="GeneID" id="9682146"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_55916"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH58757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="165" mass="17368" checksum="8D205E0FF8D45827" modified="2009-05-26" version="1">MAKLAGPGVADAGYFGFASATGGDRADLGVSAGADLAEPIATRNRTFASQFARRCKNAEAAVDASADAMRGRVLNSVIMADADAQSEIPALDRALTATRDAATRAMEVHADRAAQIPALRVRLLEACAEKKLLMERKYLAEDGPAESRMASEVKAIMDGKSKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MNX7</accession>
    <name>C1MNX7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_56069</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPB4 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057189.1">
        <property type="nucleotide sequence ID" value="XM_003057143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MNX7"/>
    <dbReference type="STRING" id="564608.C1MNX7"/>
    <dbReference type="GeneID" id="9682171"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_56069"/>
    <dbReference type="eggNOG" id="KOG2351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PEFKNCK"/>
    <dbReference type="OrthoDB" id="2186918at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030880">
        <property type="term" value="C:RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045222">
        <property type="entry name" value="Rpb4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21297">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="4">
        <location>
            <begin position="23"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH58834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="150" mass="16669" checksum="B882E65FD8AD4C35" modified="2009-05-26" version="1">MSGLACTKKVVEDEDAQELRLGEDFTDAHCLSMDEVNLICAAKLGDDLDKIGEPTSTTQTKVFEMTNAYVRRFAKEAASRQTEAFRNLYAQAGLTDFEGAIMVNLNFGDYEEAIAHLPSLARKGDDGILIHSEEKVSKLIDDMADVRRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPB1</accession>
    <name>C1MPB1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_49507</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP11 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663737">
        <property type="protein sequence ID" value="EEH58899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057254.1">
        <property type="nucleotide sequence ID" value="XM_003057208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPB1"/>
    <dbReference type="STRING" id="564608.C1MPB1"/>
    <dbReference type="GeneID" id="9682229"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49507"/>
    <dbReference type="eggNOG" id="KOG3281">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WREYHEG"/>
    <dbReference type="OrthoDB" id="16535at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010591">
        <property type="entry name" value="ATP11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126:SF0">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126">
        <property type="entry name" value="CHAPERONE ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06644">
        <property type="entry name" value="ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH58899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="250" mass="27795" checksum="D7F757E88E50EF5B" modified="2009-05-26" version="1">MAAMRGTSRALRAIRINRGATVFGSAPPPATAPRWSAVPTPERRSGMSTLIPPGKTLGEVTHVDLLEKENADVVVKIWREYHEGKSGKTGAIVEPRVYDALSDRSKVCPMFVMPLHKSMSQYLTLVVQSKMPYVSFTAIEDFRKLQDAATPMLVASHYPELAASKGLALVQAVHVDKTTAGAAEHLTTQEAVRLVRLCHTFYAEDDLYEKFVKPFNHNQKDFDFDAMVLKVRDLTWSDEHLNAGWGQDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPK4</accession>
    <name>C1MPK4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_49536</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the large ribosomal subunit (LSU).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057595.1">
        <property type="nucleotide sequence ID" value="XM_003057549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPK4"/>
    <dbReference type="STRING" id="564608.C1MPK4"/>
    <dbReference type="GeneID" id="9683092"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_49536"/>
    <dbReference type="eggNOG" id="KOG0875">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CQIASAH"/>
    <dbReference type="OrthoDB" id="1618453at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009955">
        <property type="term" value="P:adaxial/abaxial pattern specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009965">
        <property type="term" value="P:leaf morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.100:FF:000002">
        <property type="entry name" value="60S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_uL18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_uL18_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025607">
        <property type="entry name" value="Ribosomal_uL18_C_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="RIBOSOMAL PROTEIN L5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14204">
        <property type="entry name" value="Ribosomal_L18_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL18 C-terminal eukaryotes" evidence="8">
        <location>
            <begin position="243"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="299" mass="33918" checksum="BF42B8A824F5171B" modified="2009-05-26" version="1">MGKRKTKRRSNSALGVTSYFKRFQVKFARRRAGKTDYYARKRLTCQDQNKYNSPKYRLSVRFTNRDVICQVIYATLAGDVTVCAAYSHELPKYGMKAGLTNYAAAYATGLLCARRLLTKYDLAETYEGNEENLGEDYNVEAVDGERRPFKCFLDTGLVRTSTGARVFAALKGAVDGGLDIPHNDKRYAGYDLQDKSLDTDTLERYIKGGVVAEYAEEMQEEEPEKFEAHFSKYLAEDFDPTELEDNMDAVLEAIRENPVHEKKARSKPADAKSWKPKKLTYDERKAALKKKLEAIVASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>C1MPZ2</accession>
    <name>C1MPZ2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_4568</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057670.1">
        <property type="nucleotide sequence ID" value="XM_003057624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MPZ2"/>
    <dbReference type="STRING" id="564608.C1MPZ2"/>
    <dbReference type="GeneID" id="9683126"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_4568"/>
    <dbReference type="eggNOG" id="ENOG502QPYQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DTPTMGG"/>
    <dbReference type="OrthoDB" id="2020675at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044038">
        <property type="term" value="P:cell wall macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926:SF5">
        <property type="entry name" value="PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="297" mass="29730" checksum="91B290C5C07C8FAD" modified="2009-05-26" version="1" fragment="single">QPVREEGPRGHLTGAKSTTPTLGGLAFVPAGCVTAMAFTTFADPVVVATCLTTLGFLSIGAFDDVQKLLSKNNARGLSPYAKLGLQSAVATSFVAWLSSGVAAPPPSTAVALGPWMGAWSVVDLGSLFWALSAFAMVSESNAVNITDGLDGLAAATAAIALVGTGIALVASGQSELAAFSISLGGAAAGFLVVNRHPADMFMGDAGSLALGGALGAVAAAAGGAATLPLVVTTAVFIAETVSVIAQVSWFKWTKKKTGQGERLLRMAPLHHHLELGGWGELKVVATLTACAGACAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQ23</accession>
    <name>C1MQ23_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_26239</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057685.1">
        <property type="nucleotide sequence ID" value="XM_003057639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQ23"/>
    <dbReference type="STRING" id="564608.C1MQ23"/>
    <dbReference type="GeneID" id="9683136"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_26239"/>
    <dbReference type="eggNOG" id="KOG3181">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NKKKWMI"/>
    <dbReference type="OrthoDB" id="10248446at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02413">
        <property type="entry name" value="KH-II_40S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.32:FF:000004">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000006">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_uS3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005703">
        <property type="entry name" value="Ribosomal_uS3_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003219">
        <property type="entry name" value="PRK04191.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01008">
        <property type="entry name" value="uS3_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF32">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="9">
        <location>
            <begin position="21"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH57636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="232" mass="25825" checksum="85A962349AD953E6" modified="2009-05-26" version="1">MSAQISKKRKFVADGVFYAELNEMLVRELAEDGYSGVEVRVTPMRTEIIIRATRTQNVLGEKGRRIRELTSLVQKRFGFAEGSVELYAEKVANRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMENGAKGCEVVVSGKLRGQRGKAMKFKDGYMISSGNPVREYIESSVRHVLLRQGCVGIKVKIMLDWDPKGRTGPKTPVPDVVTIHNPKDEDESGLAKPYVGKELEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQE8</accession>
    <name>C1MQE8_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL23c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Large ribosomal subunit protein uL23m</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUCDRAFT_57265</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH57695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003057744.1">
        <property type="nucleotide sequence ID" value="XM_003057698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQE8"/>
    <dbReference type="STRING" id="564608.C1MQE8"/>
    <dbReference type="GeneID" id="9683182"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57265"/>
    <dbReference type="eggNOG" id="ENOG502RI4W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RERWYPP"/>
    <dbReference type="OrthoDB" id="275582at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12059:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12059">
        <property type="entry name" value="RIBOSOMAL PROTEIN L23-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEH57695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="163" mass="18635" checksum="D7EA80ECB46E5347" modified="2009-05-26" version="1">MSGPAFWESLMRAGRTIYFPNIPLRLVAPNPTAAKEGLNVVTFITTEVKGYLKAVYDVEAKRVHTVNYEGKKKRSSNGKNNYFYRRADYKKVYVQLHEKWYPPTGFASSPAGADGDAEKRREPLGKNAVKDGEKRYWLESRIAQDETGEVEMDSRGRGRARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MQR0</accession>
    <name>C1MQR0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_57379</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663738">
        <property type="protein sequence ID" value="EEH58120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058169.1">
        <property type="nucleotide sequence ID" value="XM_003058123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MQR0"/>
    <dbReference type="GeneID" id="9683241"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57379"/>
    <dbReference type="eggNOG" id="ENOG502SZDZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6344460at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053233">
        <property type="entry name" value="ABRA-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21715">
        <property type="entry name" value="RH04127P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21715:SF0">
        <property type="entry name" value="RH04127P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="394"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH58120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="446" mass="47491" checksum="B295D453A6027678" modified="2009-05-26" version="1">MPVATSAPSKKKRLAKTTKTKDARAPTRPRVSPKVRRARVLASTPILDLAPIVAFGDVGLVLRASSRRRRPLRSHHRSHSRRRQRAMSGLRSAAATSPALTALSSTIERKRDAFRAMEIRCAAQNANAPPPGTTLTGAPRPGGRSVPSSSSPRAPPSPMIRGTKSMPIPAGCSSSAYRASLLPKRSTRAAAAAGTRAGRGKNARRGGGGKRATLAPPGRARAREEEGGAGGAETPAAAAAADYDAQLAAAAEALAANVVAAAAAACAMESRVVTEESPRAIEAAAEVRVRARESSDETEKEEEMEEEEEDADADADADADAGCASDGASRDAWPRPSTPPPRASMTLHEREALLRCVSDTPPDREDVELYALYLGMDLERDEDLLFVAEWALLAPPPPGWSEHVDGSGREFYHHAATGRSSYEHPMDDTYREHYAWVKARRARGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRN1</accession>
    <name>C1MRN1_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_47336</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058903.1">
        <property type="nucleotide sequence ID" value="XM_003058857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRN1"/>
    <dbReference type="GeneID" id="9683977"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47336"/>
    <dbReference type="OMA" id="VDRCVAN"/>
    <dbReference type="OrthoDB" id="618331at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="598"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="620" mass="64667" checksum="56E3AA8B7AD6BF71" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRY0</accession>
    <name>C1MRY0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_70246</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058953.1">
        <property type="nucleotide sequence ID" value="XM_003058907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRY0"/>
    <dbReference type="STRING" id="564608.C1MRY0"/>
    <dbReference type="GeneID" id="9684392"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_70246"/>
    <dbReference type="eggNOG" id="KOG2210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="669"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="669"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="731" mass="79511" checksum="D014BC3C09294903" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>C1MRZ4</accession>
    <name>C1MRZ4_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-Ig-H3/Fasciclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUCDRAFT_58286</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058593.1">
        <property type="nucleotide sequence ID" value="XM_003058547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MRZ4"/>
    <dbReference type="STRING" id="564608.C1MRZ4"/>
    <dbReference type="GeneID" id="9684032"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58286"/>
    <dbReference type="eggNOG" id="KOG1437">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="PININGM"/>
    <dbReference type="OrthoDB" id="566721at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002910626" evidence="1">
        <location>
            <begin position="26"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="60"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEH57048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="208" mass="20992" checksum="AD0D6A13BE774FA7" modified="2009-05-26" version="1">MRSLYKLSLAAFAAAALIAPGAAEAGKTWGKHAHTYGETPKTTTGDDSTAVASDEPLANDKPLAEVLAADGDFSTLLAAVAVAKDDASAVIDDLAGEGPFTVFAPTDDAFKARRVTFLDENELTAEDVLADPVALKAILAKHVVAGTAVTAGEALAMDLPVTLESLEGSGLVVDTNDEGGVVVNGNVVVKPDLAASNGVIHGIDGVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2024-07-24" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS50</accession>
    <name>C1MS50_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_68360</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058625.1">
        <property type="nucleotide sequence ID" value="XM_003058579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS50"/>
    <dbReference type="GeneID" id="9684064"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_68360"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH57080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="131" mass="13939" checksum="6DBF81FFFB1EE154" modified="2009-05-26" version="1">MIDLLRRSRENEAAAKIQAVERGRRARGKNEGAKVKAVAQEASVAVAVAETTEAVAQEASEAELTEAVAQEASEAPQRPQQTAASAEGIRPKKRTVAYDRAEANEAKLRAVEDGLAVMGGGKRPEDAEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>C1MS93</accession>
    <name>C1MS93_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine biosynthesis bifunctional protein ArgJ, chloroplastic</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Glutamate N-acetyltransferase</fullName>
                <shortName evidence="8">GAT</shortName>
                <ecNumber evidence="8">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">Ornithine acetyltransferase</fullName>
                <shortName evidence="8">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="8">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">N-acetylglutamate synthase</fullName>
                <shortName evidence="8">AGS</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="8">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="8">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_58397</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Plastid</location>
            <location evidence="8">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the ArgJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="8"/>
    <dbReference type="EC" id="2.3.1.1" evidence="8"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058642.1">
        <property type="nucleotide sequence ID" value="XM_003058596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MS93"/>
    <dbReference type="STRING" id="564608.C1MS93"/>
    <dbReference type="MEROPS" id="T05.002"/>
    <dbReference type="GeneID" id="9684081"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58397"/>
    <dbReference type="eggNOG" id="KOG2786">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="WGRIVMA"/>
    <dbReference type="OrthoDB" id="2017946at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006592">
        <property type="term" value="P:ornithine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.340:FF:000001">
        <property type="entry name" value="Arginine biosynthesis bifunctional protein ArgJ, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="entry name" value="ArgJ beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.70.12">
        <property type="entry name" value="L-amino peptidase D-ALA esterase/amidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100:SF0">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="DmpA/ArgJ-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 8" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="8" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5023214451" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="8">
        <location>
            <begin position="1"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023214449" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="8">
        <location>
            <begin position="240"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="8">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="8">
        <location>
            <begin position="239"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH57097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="458" mass="47129" checksum="B6481BC096225CDD" modified="2009-05-26" version="1">MALRRRITPPRTAALKAGLRATGTRADCALVVADEPALSAGVFTKNMVAAAPVLYCKETMANNARARAVLVNAGQANAATGTKGMEDSVASANAVAAALGIDASEVLLESTGAFYLTLVPIRPRRRGERRSLRTFPGVSLRPHLAFNPRPRRLSTSTDAFQLQGVIGKRIKMPELLAAVPTLAANLSAGADAAAAAATAICTTDLVRKSIAIEVDLGGGRRAKIGGMGKGSGMIHPNMATMLGVITTDANVDAAAWKAMLKRAATNSFNQISVDGDTSTNDTVIGLASAAAGGDVIEEGSKEAATLERAVEAVCVAVAKSIAWDGEGATCLIECVVTGATSDADARRVARSVISSSLVKSAVFGHDPNWGRLAAAAGYAGVDFEQSDLRIALGPHVLMERGQPLDYDAVAASAYLKETTGRHGTVTVDVSVGGGGGAGTAWGCDLTYDYVKINAEYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSB9</accession>
    <name>C1MSB9_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_17417</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059025.1">
        <property type="nucleotide sequence ID" value="XM_003058979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSB9"/>
    <dbReference type="STRING" id="564608.C1MSB9"/>
    <dbReference type="GeneID" id="9684093"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17417"/>
    <dbReference type="eggNOG" id="KOG0939">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF67">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HUWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH57480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="109" mass="11869" checksum="E02E559C30DD27C7" modified="2009-05-26" version="1">MYASSTAAAGGGGGGEGIVEWFWRAVESFTAERRANLLTFWTGAAVLGPNGFHECDFRLTLASHLSPESLPESQTCSRTIKLARYVTYEQLREKLVSAIEYGARGFAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSF6</accession>
    <name>C1MSF6_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUCDRAFT_47426</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058670.1">
        <property type="nucleotide sequence ID" value="XM_003058624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSF6"/>
    <dbReference type="STRING" id="564608.C1MSF6"/>
    <dbReference type="GeneID" id="9684485"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47426"/>
    <dbReference type="eggNOG" id="KOG0589">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="SHPWFNL"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08530">
        <property type="entry name" value="STKc_CNK2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000097">
        <property type="entry name" value="Probable serine/threonine-protein kinase nek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF6">
        <property type="entry name" value="SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="16"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="355"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="426"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="591"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="593"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEH57125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="617" mass="66566" checksum="6BE8E3E78BB5CF44" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSX1</accession>
    <name>C1MSX1_MICPC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="9">1.3.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MICPUCDRAFT_57858</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCMP1545</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.88" evidence="9"/>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058395.1">
        <property type="nucleotide sequence ID" value="XM_003058349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSX1"/>
    <dbReference type="STRING" id="564608.C1MSX1"/>
    <dbReference type="GeneID" id="9684195"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57858"/>
    <dbReference type="eggNOG" id="KOG2335">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="LRFCERY"/>
    <dbReference type="OrthoDB" id="272303at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="DUS-like FMN-binding" evidence="15">
        <location>
            <begin position="51"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEH56850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="440" mass="48889" checksum="233D89ED7B1FD28B" modified="2009-05-26" version="1">MAAVDDAVAVAGDPPTADAADAPAPAIATTPQTKLKGYAFFESMGSPRFHVAPMVDQSELAFRTLCRRYGATLAYTPMIHARLFVEDLKYRAEIFTTVEGIADRPLLVQFCANDPATLLAAAKLVAPHCDGVDINFGCPQRIAKKGRYGAFLMDDWKTVHDLISILDKELSVPVTAKIRVYDDLETSIQYAEMVQNAGAQLVAIHGRTREQKRASDVRANWAFIKAIKERLTVPVIANGDVRTLAEARKCLEATGADGVMSADPLLENPSLFSDPPFAPTRDLANPLPIEGDANCRLLMEYLDITQLPGHHTPLRMIKAHVFKMVGHWLAEFTDLRDWLNREKYEKITIDALRAWTKELTGRVRLIAKKEGRLRPIAKKSERALAREAAEEAERIKTAAIEEQKREDDAIAGARRFGFFWFGFFFSAGGAVRFFFILDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1MSZ2</accession>
    <name>C1MSZ2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fanciful K+ uptake-b family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_9543</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058767.1">
        <property type="nucleotide sequence ID" value="XM_003058721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MSZ2"/>
    <dbReference type="STRING" id="564608.C1MSZ2"/>
    <dbReference type="GeneID" id="9684206"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9543"/>
    <dbReference type="eggNOG" id="ENOG502S21M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DVTPVIW"/>
    <dbReference type="OrthoDB" id="4696at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219:SF14">
        <property type="entry name" value="PROTEIN COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="YLMG HOMOLOG PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="CCB3_YggT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="82" mass="9009" checksum="AE8815483D702678" modified="2009-05-26" version="1" fragment="single">LGPFFALGTVAFIVRIVMTWYPSVPYTKLPWVIAYVPTEPLLKPTRALVPPVGGVDVSPIIWVGMISFMNEILLGKQGLLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>C1MT38</accession>
    <name>C1MT38_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_57926</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058425.1">
        <property type="nucleotide sequence ID" value="XM_003058379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MT38"/>
    <dbReference type="GeneID" id="9684232"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_57926"/>
    <dbReference type="OrthoDB" id="539293at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="225" mass="22692" checksum="4EAFB234F4D41C59" modified="2009-05-26" version="1">MRAGASSSASSPSVAAAFAFARASATTDGVLLGGRHDEIRASTSSSTRHHHLASSLAHARSFARPSRRAPNASAAASSSENALKRPRRPSEHWQPVDDAKTKMRYWWNKSTGETTGLGEPRPTSFKLPPADKWSALTKHVDKNGEPTLGVAIGQMFVFAFGGALGVTAVSVALGVLSGGGGGAAAAGMEGKDDGGATSSGNDAVARGAATRGATVARRVAAAGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTJ9</accession>
    <name>C1MTJ9_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_5130</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH57330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058875.1">
        <property type="nucleotide sequence ID" value="XM_003058829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTJ9"/>
    <dbReference type="STRING" id="564608.C1MTJ9"/>
    <dbReference type="GeneID" id="9683943"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_5130"/>
    <dbReference type="OMA" id="DTEWIVH"/>
    <dbReference type="OrthoDB" id="9985979at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007877">
        <property type="entry name" value="DUF707"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31210">
        <property type="entry name" value="OS06G0731900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31210:SF43">
        <property type="entry name" value="STORAGE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05212">
        <property type="entry name" value="DUF707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH57330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="288" mass="32124" checksum="31CA485DEE0B0A83" modified="2009-05-26" version="1" fragment="single">ARNIPPRIRARTTDLRPRRLEGSPADDAPIARNLLALTVGVKQKDVVDALVRTFLSSASTSDAASSSDPASDAFSVILFHYDGEVDAWRTLPWSDDVVHVSVSKQSKWWYAKRFLHPDVVRPYDHVFLWDEDIDARDSKFDPREYLRIVRENGLHISQPAIVAGNGAWPITRVVRRENETTGGEPLGEFHRLGADWNGNRCVDDDGNPTTRPPCAAYVEIMVPVFTRRAWRCVWEMIQNDLSHGWGLDLTWQLCAADDTKNATAVDGMGVVDAQGITHLGAPTLTEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>C1MTN6</accession>
    <name>C1MTN6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUCDRAFT_58137</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663739">
        <property type="protein sequence ID" value="EEH56979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003058524.1">
        <property type="nucleotide sequence ID" value="XM_003058478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MTN6"/>
    <dbReference type="STRING" id="564608.C1MTN6"/>
    <dbReference type="GeneID" id="9684331"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58137"/>
    <dbReference type="eggNOG" id="KOG4149">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CMVENAS"/>
    <dbReference type="OrthoDB" id="7481291at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045041">
        <property type="term" value="P:protein import into mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039289">
        <property type="entry name" value="CHCHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21622">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21622:SF0">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEH56979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="98" mass="10141" checksum="1E27A12036DDFA21" modified="2009-05-26" version="1">MAAAGEAIAEAIARGDGAAGTTEDAIKAAMECPCVADLKNSACGEAFAGALGCFMSADAEERGSKCVKEFVAMHACMVENSKEFEAFTAELVEAKERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1MU66</accession>
    <name>C1MU66_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Monovalent Cation:Proton antiporter-2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MICPUCDRAFT_40144</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059144.1">
        <property type="nucleotide sequence ID" value="XM_003059098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MU66"/>
    <dbReference type="GeneID" id="9684510"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40144"/>
    <dbReference type="eggNOG" id="KOG1650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="IPFLELW"/>
    <dbReference type="OrthoDB" id="1935933at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562">
        <property type="entry name" value="NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562:SF3">
        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="11">
        <location>
            <begin position="22"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEH56276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="421" mass="42426" checksum="E7E096A193D22BAD" modified="2009-05-26" version="1">MASTLYEIARLWITFIALACGGKLGELVHAPLVGEIVVGLLLGPSGANFIPEPDGVVLLGNLGLCVLVMTGGLSIDVDALAHVGPVAIAIAVTGTLLPIALGCAFMTAAGYSPAVGVAAGTALSSTSIGMATNTMAAANALHTRIGSLVCVAAMIDDVLSLVILAVLGNVGGSSDDAGALTWAIGRPVMVSVAFVVVGAGAARVVPRVFAREWGWATRAGETLTKMKRDDVVVASMLTLTLGLVVACGAAGSTYLLGAFVGGYAFAAAPNAKDAWAKYDLLSARLASIFFLSVGMQIPLADLFDGAGAGLGIGYAVPAVLGKLATGAFVRDVGDAAVVGWAMVGRGELGFVMAREALDEGLFGDTPYVACVWALLIATLVSPVFMRRALERRKAAGGWAAGDVGAAEDGADAVEIGRHDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUB5</accession>
    <name>C1MUB5_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_17947</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059468.1">
        <property type="nucleotide sequence ID" value="XM_003059422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUB5"/>
    <dbReference type="STRING" id="564608.C1MUB5"/>
    <dbReference type="GeneID" id="9684908"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_17947"/>
    <dbReference type="eggNOG" id="KOG0472">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="DEIANCK"/>
    <dbReference type="OrthoDB" id="566279at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="175" mass="18687" checksum="EA8F47BD36F06586" modified="2009-05-26" version="1" fragment="single">SLGAALTTLASEISRLSGLMTLILSDNALTSLPESIGELKRLKVLEAERNALTSVPSSLSDCACLEILRLGHNKLTSVKALAACNELVTLVLDDNELTTLDDLDVASKSRLVTLSAKKNAIERVPGNLGKCALLAELCLGDNAIENLPKSLGELKEKKVRALEFEGNPLRDPKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUG7</accession>
    <name>C1MUG7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_18039</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SDO1/SBDS family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059194.1">
        <property type="nucleotide sequence ID" value="XM_003059148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUG7"/>
    <dbReference type="STRING" id="564608.C1MUG7"/>
    <dbReference type="GeneID" id="9684932"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18039"/>
    <dbReference type="eggNOG" id="KOG2917">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TIISAKC"/>
    <dbReference type="OrthoDB" id="10253092at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1250.10">
        <property type="entry name" value="Ribosome maturation protein SBDS, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.900">
        <property type="entry name" value="SBDS protein C-terminal domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036786">
        <property type="entry name" value="Ribosome_mat_SBDS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002140">
        <property type="entry name" value="Sdo1/SBDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039100">
        <property type="entry name" value="Sdo1/SBDS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018978">
        <property type="entry name" value="SDO1/SBDS_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037188">
        <property type="entry name" value="Sdo1/SBDS_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019783">
        <property type="entry name" value="SDO1/SBDS_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00291">
        <property type="entry name" value="RNA_SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10927">
        <property type="entry name" value="RIBOSOME MATURATION PROTEIN SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10927:SF1">
        <property type="entry name" value="RIBOSOME MATURATION PROTEIN SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09377">
        <property type="entry name" value="SBDS_domain_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01172">
        <property type="entry name" value="SBDS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89895">
        <property type="entry name" value="FYSH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109728">
        <property type="entry name" value="Hypothetical protein AF0491, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS N-terminal" evidence="8">
        <location>
            <begin position="21"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS central" evidence="9">
        <location>
            <begin position="116"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="197" mass="22354" checksum="ACAA07FF571BA450" modified="2009-05-26" version="1">MSGRASITQLALPTGIKKLTNIAVVRLKKHGVRFEIACYKNTVAAWRDKFEKDMDDVVQTTQIYNNVSKGVLAKEEDLMRAFGTTDEKTICRVILDVGEMQVSDKERKLNFDTLFRDVVNVLVDKCVNPETNRPYPPGMIERALRDVHFSVDPMKSAKQQALAALPKLGAVFPIKRAAMRFRRVRIYTGPHTTPFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1MUK6</accession>
    <name>C1MUK6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_58845</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059511.1">
        <property type="nucleotide sequence ID" value="XM_003059465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MUK6"/>
    <dbReference type="GeneID" id="9684654"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_58845"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="266" mass="28521" checksum="A5934753E1BD6622" modified="2009-05-26" version="1">MGNQSEISSEAFSARELPKKRSRSRSVLIVGQGTESWLLIVPAHSTPRDAADAATTTSIPVVTPSLARPRVDARPASSASSAEGGDQRDTCANKRSLPHYSDELNNEFSRSKRSSDASIGMTFASACTASDVVGHRITVDAADVLVIAAADASERDLVARAERASVHLRKLRPNDLVTVVEQPSRPRTFVPPGYGLPLTQEVAAKMGATVHSMTRDASQLASHDGGAKARGCVVPARSLPNRFSPRFFSRIVSTNLSRSEKCTVRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV65</accession>
    <name>C1MV65_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MICPUCDRAFT_59069</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCMP1545</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS72/YL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059321.1">
        <property type="nucleotide sequence ID" value="XM_003059275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV65"/>
    <dbReference type="STRING" id="564608.C1MV65"/>
    <dbReference type="GeneID" id="9685053"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59069"/>
    <dbReference type="eggNOG" id="KOG2897">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="ASFWGQA"/>
    <dbReference type="OrthoDB" id="78296at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046757">
        <property type="entry name" value="YL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05764">
        <property type="entry name" value="YL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="3">
        <location>
            <begin position="312"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEH56453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="426" mass="45601" checksum="8FF854EAF00F7AF5" modified="2009-05-26" version="1">MASTALPKRSTRGLRMNKLLEDEDSADEEFWGQDAFAEESGDEEYSSESEEADVFDKDFDDDESSSDSEEVVVAKERRKPALKAPERKAPPAPRAAATATKERAKKPPRGLDGMSVFSPDGLEWSDGGGARVDNDGGLRKSSRASVKQILSESERSREERRSKAPPKRTAPAEPARPLTQAEILAEAAVTEARPLSDTGLSLPAGVSLRPSPLAFNPDTPRRLSTPPLTPFDSAPTSLRTGNYPQVWNLRDLEYLLNLEEATKKKAERVKTTFTGPTLRVRSVGDKTTIEPRYGASLPEPLGMKAPTPPTPERCVVTGDRARYRDPLTGLAYKDVAAFKELRRRHAATTAAAKKDAVVGVVEVQAGVAAAPAPAKAPAKASAAVAETSQFAVKTFSSGSPVDSPSGGSGGKAKKRKLASLNEISKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MV97</accession>
    <name>C1MV97_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_69774</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059335.1">
        <property type="nucleotide sequence ID" value="XM_003059289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MV97"/>
    <dbReference type="GeneID" id="9684775"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_69774"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="242" mass="26988" checksum="37452E319E7139D2" modified="2009-05-26" version="1">MPFNSTSDAFALHPDIIASYGPSYPQSARGLGHLLSIRWGGRRRVRARPRRRGAAARGPARLPHDPARGRAGRGRDDERVAVRGRGHSPRHALLLGRIRGVRVPAVAVRRGEKRPRRRRDGGAVRRVDARVAAGADARVPRRVLRRRAGADRRRREGREESRRGTAAGVGRLGGGPPKRSRTARAGRAVRGRDRRRRRERRGRAVRRDAADGPADVARGGHAVRGRGREKKRACFRARHHRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1MVB3</accession>
    <name>C1MVB3_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUCDRAFT_59129</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCMP1545</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Accepts the ubiquitin-like protein NEDD8/RUB1 from the ECR1-AXR1 E1 complex and catalyzes its covalent attachment to other proteins.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="GG663740">
        <property type="protein sequence ID" value="EEH56477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059345.1">
        <property type="nucleotide sequence ID" value="XM_003059299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MVB3"/>
    <dbReference type="STRING" id="564608.C1MVB3"/>
    <dbReference type="GeneID" id="9685077"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59129"/>
    <dbReference type="eggNOG" id="KOG0420">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="NIDERGN"/>
    <dbReference type="OrthoDB" id="10249039at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019788">
        <property type="term" value="F:NEDD8 transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000005">
        <property type="entry name" value="NEDD8-conjugating enzyme Ubc12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00058311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEH56477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="153" mass="17188" checksum="D562EE93B5404CBE" modified="2009-05-26" version="1">MRLAKDISELTLSPSISVDFPDGKDKLLDFIVTIRPEDGFYRGGVFRFSFAVPGTYPHEPPKVKCLAKVYHPNLDHDGNVCLNILREDWKPVLSVSSCVYGLTFLFSDPNPDDPLNKEAAKEMTESPRQFEQNVRRSMQGGYVGGTTFSNVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWC6</accession>
    <name>C1MWC6_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_59716</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060191.1">
        <property type="nucleotide sequence ID" value="XM_003060145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWC6"/>
    <dbReference type="GeneID" id="9685341"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_59716"/>
    <dbReference type="OMA" id="ISERHLM"/>
    <dbReference type="OrthoDB" id="2019121at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEH56143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="347" mass="37184" checksum="00C431063D288E4B" modified="2009-05-26" version="1">MFAAIESGTARTPWGFDQTTGAASYLGNNDEQRISERHLMHHLDVMTRGFQVETRTRIPAKKLHVRLTRIDASPSASARATAVLAAWDGFPAVSRASAGHAHVVMNGHVGNAREMRELYALPPAEPTGPHFIAKMDGSIVPPPPSPPPSHEGAALILALYAKRFEDKDGDPSDQPSTALTACEGEFVIRLRSFSFVLIDEEKDVVLVARSAESDTHPMFWGTAPSNGGEDGTSTDASHASDDWDGALLLSNDLAAIDVACGGAAAAFPLGAYYYRDASMDVGVIQARSISNWSPYDRVGVRLAVNCRGVKRRVNPLHRVNSSGQVCGLGFFTESGSDLASLSHKFIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWE2</accession>
    <name>C1MWE2_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_9459</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060200.1">
        <property type="nucleotide sequence ID" value="XM_003060154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWE2"/>
    <dbReference type="STRING" id="564608.C1MWE2"/>
    <dbReference type="GeneID" id="9685638"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_9459"/>
    <dbReference type="OrthoDB" id="498085at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021518">
        <property type="entry name" value="DUF3181"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11378">
        <property type="entry name" value="DUF3181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="92" mass="10342" checksum="BD3D728BB4DDA98A" modified="2009-05-26" version="1" fragment="single">VSELAEKLGKDIYMDVNGWHLFLRDAKYATPLSKIIAARLAADGNRYDEDAALQLLRECPVKIGGGKQSVKLFDLMPRVVVDDYLKIVEEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWF0</accession>
    <name>C1MWF0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUCDRAFT_18243</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH56156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060204.1">
        <property type="nucleotide sequence ID" value="XM_003060158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWF0"/>
    <dbReference type="STRING" id="564608.C1MWF0"/>
    <dbReference type="GeneID" id="9685642"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_18243"/>
    <dbReference type="eggNOG" id="KOG0230">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="158357at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000285">
        <property type="term" value="F:1-phosphatidylinositol-3-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000007">
        <property type="entry name" value="1-phosphatidylinositol 3-phosphate 5-kinase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748:SF7">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEH56156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="249" mass="26445" checksum="21C829877526BFA1" modified="2009-05-26" version="1">MASSRGASRIVLLAGALEYQRGESPAAPRLSSMDALLDQEHEHLRAAVARVCDLAPDVLCVERTVARFAQELLLERGVSVVLRVKTSALRRLARSTGASIAAAVDELTENAVGVCGEFRVESHAETRELGEEGEGEDAGGGGGGVKTLMTFDKCPAVGLGCSVLLKGASARELGVVKTALRDAIVWAHHAEREGAWLAAFATAAADDDDDDATSEWPPPPPQSRAVAIRRVLFSHWSPYDRVRVVNADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWR7</accession>
    <name>C1MWR7_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUCDRAFT_40449</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059971.1">
        <property type="nucleotide sequence ID" value="XM_003059925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWR7"/>
    <dbReference type="STRING" id="564608.C1MWR7"/>
    <dbReference type="GeneID" id="9685142"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_40449"/>
    <dbReference type="eggNOG" id="KOG1657">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="TRTITHF"/>
    <dbReference type="OrthoDB" id="498726at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23645">
        <property type="entry name" value="HFD_Dpb3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF54">
        <property type="entry name" value="CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="6"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="6"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="169"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEH55923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="226" mass="24019" checksum="6CD419624D1E74CD" modified="2009-05-26" version="1">MAGGKQKGKIAPYLVYANEVREDVKRALVDAGAVKPTMGEIAKAVGVRWKTLSDAQKATYKEKADAINAETAATRAADAEGGEAGEDGDDEDGEEEIVTLPLARVKRIMKCDKEVKTAAVDAAKVVSKATELFLESLTEGAFLGMKAGKRKTVKYDDLEGFVMRKPRLEFLHDHDKENKEDGDEDGGPPEAPSGARQVTEFFTKKAATPAAATDAAAADGDDGDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1MWX0</accession>
    <name>C1MWX0_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MICPUCDRAFT_47657</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059704.1">
        <property type="nucleotide sequence ID" value="XM_003059658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MWX0"/>
    <dbReference type="STRING" id="564608.C1MWX0"/>
    <dbReference type="GeneID" id="9685434"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47657"/>
    <dbReference type="eggNOG" id="ENOG502QSRR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="RMDASNH"/>
    <dbReference type="OrthoDB" id="103454at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000972">
        <property type="term" value="P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037624">
        <property type="entry name" value="Nup133-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13405">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13405:SF11">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="405"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEH55656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="1167" mass="118265" checksum="12AC70129704ADFC" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX07</accession>
    <name>C1MX07_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUCDRAFT_47668</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCMP1545</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG663741">
        <property type="protein sequence ID" value="EEH55675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003059723.1">
        <property type="nucleotide sequence ID" value="XM_003059677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX07"/>
    <dbReference type="STRING" id="564608.C1MX07"/>
    <dbReference type="GeneID" id="9685452"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_47668"/>
    <dbReference type="eggNOG" id="KOG0236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="VKCAVMA"/>
    <dbReference type="OrthoDB" id="540766at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="SLC26A/SulP transporter" evidence="7">
        <location>
            <begin position="125"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEH55675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001876"/>
        </source>
    </evidence>
    <sequence length="559" mass="57613" checksum="363719730B42A883" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>C1MX30</accession>
    <name>C1MX30_MICPC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUCDRAFT_8511</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Micromonas pusilla (strain CCMP1545)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="564608"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCMP1545</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG663742">
        <property type="protein sequence ID" value="EEH55388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003060619.1">
        <property type="nucleotide sequence ID" value="XM_003060573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1MX30"/>
    <dbReference type="STRING" id="564608.C1MX30"/>
    <dbReference type="GeneID" id="9686056"/>
    <dbReference type="KEGG" id="mpp:MICPUCDRAFT_8511"/>
    <dbReference type="eggNOG" id="KOG0715">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OMA" id="CHREQVP"/>
    <dbReference type="OrthoDB" id="498825at2759"/>
    <dbReference type="Proteomes" id="UP000001876">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF10">
        <property type="entry name" value="MRJ, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
